第十四改正日本薬局方第一追補
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- きみお みしま
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1 395
2
3 d 66 dl
4
5
6
7
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9 9
10 10
11 11 5 2
12 12 d dl
13 13
14 14
15 15
16 16
17
18 3
19 5
20 7
21 8 A AλAλ A Aλ A A W V A V W V Aλ A λ λ Aλ A AA A A W V f f A A A A A V W V f
22 9 R α β β
23 10 E x H N N
24 11 H de Micrococcus luteus E
25 12 N N N N N N N N R n
26 13 n E α E
27 14 N N x n α NN N N
28 15 α R E R
29 16 R n R ρ ρ M V ρ M V V M M ρ ρ M M V ρ M M V
30 17 V ρ ρ M V ρ M V M V M ρ ρ M M V ρ M M V κ ρ Ω ρ A l R Ω R ρ l A κ κ 1ρ 1R l A l A R
31 18 G R Ω A l C C α l A α κ ρ Ω κ κ T T κ κ R R G C C Rκ C κ G RΩ G κ G RΩ C κ κ CG κ C R
32 19 O Thr-D-Val-Pro-MeGly-MeVal N O NH 2 O O CH 3 CH Thr-D-Val-Pro-MeGly-MeVal MeGly = N - MeVal = N - R α A A H 2 N W O A O H A CO 2 NH CH 3 W 5 Al 3 (OH) 4 S
33 20 R α Q Q W W Q Q
34 21 AAAA A A AA A A A A A A Bacillus subtilis
35 22 α A A W A A W Q Q
36 23 W Q Q W α N N N N N N Q Q N N N N W Q W Q WN N W N N
37 24 N N N N N N N N N N Q Q W Q Q W α
38 25 Q Q W Q Q W α
39 26 Bacillus subtilis A A W W A A Q Q W Q Q W
40 27 Q Q WS Q Q WS N
41 28 α N N N N N A A W A A W N N
42 29 Q Q W W Q Q Q Q W Q Q W H 3 C H 3 C S N N N N Cl H f a
43 30 N N R α
44 31 t N N N N Staphylococcus aureus Q Q W Q Q W n
45 32
46 33 x
47 34 A A A W W A A A A2 W W α
48 35 A A H 3 C W O O A A OH W H O OH H O HO O CH 3 H H H NH 2 O OH OH HCl S S α arabino α N N N N N N
49 36 Q QQ QQ Q Q Q W W W Q Q W Q Q Q Q Q Q W N N Q Q W Q Q W α
50 37 β β β α β β t t α α β α α β α β A A W A A W
51 38 α Micrococcus luteus H 3 C H CH 3 N H N H H H O HO H OH H H Cl CH 3 O H H HCl S CH 3 OH S R threo α galacto d
52 39 d cis H HO H H H H N O O CH 3 H 3 C H H H 2HCl 5H 2 O HO O H H NH HO O H 3 C R R R S S R S R S H b α Klebsiella pneumoniae
53 40 p p p Q Q Q Q p p p δ δ δ α
54 41 WS AT WT AS W W A A WS AT WT AS W W A A A A AAA
55 42 Q Q WS Q Q WS δ δ α H
56 43 H H WS AT WT AS WS AT WT AS WS ST WT AS WH W W A H A A H ST H H H H Q Q WS Q H 3 C O O OH H O OH H O H O CH 3 H HO H NH 2 Q WS O CH 3 OH HCl S S α lyxo
57 44 α Q Q WS Q Q WS α
58 45 V WS V V V WS OH Cl HO O H H OH O OH O OH H H N H 3 C CH 3 NH 2 HCl S S S S S α
59 46 A A WS A A WS t E
60 47 α t Q Q W W W W A A Q Q
61 48 WS A A WS N N n α
62 49 A A WS A A WS Q Q WS Q Q WS Q Q WS Q Q WS
63 50 α α
64 51 V V WS V V WS A A WS A A WS α
65 52 Bacillus subtilis α
66 53 Q Q WS Q Q WS
67 54 Mycobacterium smegmatis Q Q W Q Q W
68 55
69 56
70 57 Q W Q Q Q W Q Q W Q Q W
71 58 H 3 C N CH 3 O S H N H 3 C * NO 2 NH HCl * N N R A A W A A W
72 59 α A A W A A W
73 60 H 2 N H O O H N H N H H S O O CH 3 CH 3 O CH 3 O O HCl S R R R N N α Q Q W Q W Q W W N N N N N N Q Q Q Q Q Q
74 61 W W QQQ QQ W QQQ W QQ W W W N N Q Q W Q Q W
75 62 H 3 C N N F O CH 3 H N O CO 2 H RS H de
76 63 A A AAA
77 64 A A W A A W δ δ α
78 65 W A W A W W A A W A W A W W A A Q Q W Q Q W
79 66 d d d dl dl
80 67 Q Q W W Q Q HO 2 C HO CO 2 H CO 2 H H 2 O
81 68 HO CO 2 H HO 2 C CO 2 H
82 69 A A AAA AAA Q Q W Q Q W n α
83 Bacillus brevis Enterococcus hirae
84 71 N N α N N Q Q Q QQ QQ N N Q Q
85 72 W Q Q W N N α
86 73 α
87 74 A A W A A W Q Q W Q Q W Q Q W Q Q W
88 75 A A W A A O 2 N H OH H H N O O Cl Cl CO 2 Na W O R R α Q Q W Q Q W Q Q W
89 76 n H H W H H W Q Q W Q Q W
90 77 Q Q W W Q Q R V W V W
91 78 α Q Q W Q Q W Q Q W W Q Q
92 79 H 3 C OH H O H O CH 3 H CH 3 CH 3 S S R S S H a mn α Q Q W Q Q W
93 80
94 H R 2 O CH3 OH H CH 3 H OHC H3C H H CH 3 O H O H H N CH 3 H H CH 3 R 1 O O H O H OH H CH3 O OH H O R 1 = -H R 1 = R 1 = R 1 = -H R 1 = R 1 = -H R 1 = R 1 = -H R 1 = -H O O CH3 H C CH 3 O C CH3 O C CH 3 O C CH3 H HO 2C R 2 = R 2 = R 2 = R 2 = R 2 = R 2 = R 2 = R 2 = R 2 = OH CO 2H H O C O C O C O C O C O C O O OH C CH3 C CH 3 R R S R R R E E R O O C α ribo β R R R R S R R R E E R O O C α ribo β R R O C CH 3 CH 3 CH 3 CH3 CH 3 CH3 CH3 CH 3 CH 3 n n
95 82 Bacillus subtilis Q Q W Q Q W
96 83 Bacillus subtilis α
97 84 Bacillus subtilis N N δ δ α NN
98 85 Q Q W Q Q W N N
99 86 δ δ δ α H H H Q Q Q Q m n H H H Q Q W Q Q W n
100 87 δ δ δ α A A W A A W
101 88 δ δ δ α Q Q W Q Q W
102 89 δ δ δ δ α A A A A A A A A
103 90 Q Q W Q Q W H 2 N N S CH 3 O N O O H N N CO 2 Na S H H S S N CO 2 Na CH 3 R R Z δ δ δ α
104 91 Q Q W Q W Q W W Q Q W Q Q W
105 92 δ δ δ α A A W A A W
106 93 δ δ δ δ α H H Q Q Q Q Q Q H Q Q H H W Q W Q W Q W Q W Q W Q W Q W Q W Q W Q W Q W Q WH W W
107 94 l d l l l d l Q Q W Q Q W E α Q Q W Q Q W n
108 95 δ δ δ α Q Q W Q Q W
109 96 n
110 97 n Q Q W Q Q W n δ δ δ
111 98 α H H H W W A A W W H W W A H A A H A H W A A H H H Q Q W Q Q W
112 99 δ δ δ α Q Q W Q Q W n
113 100 H 2 N N S CH 3 O N O H N O H H O H 3 C * O O O N H S O O CH 3 CH 3 CH 3 RS R R Z δ δ δ δ α
114 101 A A AAA Q Q Q Q W QQ QQ W δ δ δ α
115 102 Q Q W Q Q W
116 103 δ δ δ α Q Q W Q W Q W W A A AAA
117 104 Q Q W Q Q W
118 105 S S S S SSS S SSS S SSS N N
119 106 H H W W H H δ δ δ R α Bacillus subtilis
120 107 HO HO OH O OH OH R 1 OH R 2 O O O CH3 NH2 O CH 3 OH O Q Q W W Q Q CH 3 O H O H HO NH2 H A: R 1 =H, R 2 =OH HO B: R 1 =OH, R 2 =H H H β β
121 108 A A W A A W
122 109 Q Q Q Q W Q Q W Q Q W W A A A A W A A C W A A C W W C C
123 110 Q Q Q Q W Q Q W Q Q W W Bacillus subtilis Bacillus licheniformis R A A AA Micrococcus luteus
124 111 O 2 N H OH H N O Cl Cl H O O CH 3 R R R α
125 112 A A W A A W R V W V W
126 113 Q Q W W Q Q Q Q W Q Q W
127 114
128 115 H HO CH 3 H NH 2 H H HO 2 C H O O HO H H H H O OH OH H OH H O O H O CH 3 H R S R R E R E E E E R S R S β α
129 116 AAAAA A W A AA A AA W O OH H O O OH H O 3 C H H O CH 3 H H O O H NH 2 O OH S S { O R αlyxo } OH R α
130 117 Q Q W Q Q W Cl H N NO 2 Cl
131 118 Q Q W Q Q W d AA A AA AA A A
132 119 AA H 3 C O * H O O H N H N H H S CO 2 K CH 3 CH 3 S R R RS α α α α A A AA A α α α α α α α α α α α α α V V
133 120 W V V W H 3 C CH 3 H HO OH H H H 3 C CH 3 H 3 CH H H CH 3 CO 2 Na O H O CH 3 O S Z ent α β β β β α β α N CH 3 HO 2 C CO 2 H Staphylococcus aureus H b H
134 121 Q Q Q Q
135 122 Bacillus subtilis
136 123 δ δ δ α H H H Q Q H H W Q Q W H Q Q W Q Q W
137 124 m n α
138 125 Staphylococcus aureus H CO 2H O N CH3 H N S CH3 N H H N 4H2O H H O 2 S R R N N α
139 126 Staphylococcus aureus NN N N
140 127 H H H H N N
141 128 N N A A W A A W NN O O H 3 C O CH 3 H 3 C H 3 C N O H 3 C H 3 C O CO 2 H CO 2 H RS N N N N
142 129 Q Q W W Q Q
143 130 α β W MMMM MMMM W M M α M M β M M α M M β α β α α β
144 131 A A W A A W Q Q W Q Q W n
145 132 H3C H CH3 HO H CH3 CH3 H 3C HO OH O O CH 3 H H O CH3 N H H CH 3 H H CH3 H H H O O OH HO O H CH 3 CH 3 O CH 3 H H CH 3 O H HO H H OH HO CO 2H HO H H OH HO O O H OH H H H R S S R R R R R S R β xylo C O α ribo O β R ph Staphylococcus aureus H HO δ δ α
146 133 ph H H A A AA Q Q W Q Q W m n
147 134
148 135 A A W A A W α ph
149 136 o Bacillus subtilis R α ph Q Q W Q W Q W W
150 137 o Bacillus subtilis
151 138 HN O H R H H NH HN O HO H HN O HN HN H HO HN NH O H O NH HN H 2 N O O H 2 N N : R = OH O : R = H H NH H 2 SO 4 2 R R N S S S S R Z S N S S S S R Z α ph A A AAA Bacillus subtilis
152 139 R α ph Bacillus subtilis
153 140 H 2 N H H OH HO H HO H HO O H H H NH 2 H HO O H H OH H NH 2 O H H HO O H H NH 2 H 2 SO 4 O α O α R α Bacillus subtilis
154 141 R α ph R A R A R A A A A A A A A A A A A A R R R Staphylococcus epidermidis
155 142 R CH3 O R = CH3 R = H N 4 Dbu-Thr-Dbu-Dbu-Dbu-D-Leu-Leu-Dbu-Dbu-Thr H2N Dbu = Dbu = H2N H NH 2 H CO2H CO 2H NH H2SO 4 R R R α ph Escherichia coli
156 143 R R R R α ph Bacillus subtilis
157 144 R α ph Bacillus subtilis R α ph
158 145 R Staphylococcus aureus ph
159 146 Mycobacterium smegmatis
160 147 R α ph Bacillus subtilis α ph
161 148 Mycobacterium smegmatis
162 149 R R α ph A AAA A A A A A A W W Escherichia coli ph
163 150 R α Bacillus subtilis R α
164 151 Bacillus subtilis α Q Q W Q Q W
165 152 Q Q W Q Q W Q Q W Q Q W
166 153 Q Q W Q Q W Q Q W Q Q W Q Q W Q Q W
167 154 A A A A Q Q W Q Q W Q Q W Q Q W
168 155 n Q Q W W Q Q
169
170 159
171 161 R R R R Aloe ferox Aloe africana Aloe spicata Liliaceae A A W A W A
172 162 R Clematis chinensis Clematis manshurica Clematis hexapetala Ranunculaceae
173 163 R R R R R
174 164 R R R R Polygonum multiflorum Polygonaceae Pueraria lobata Leguminosae R
175 165 A A W A A W R R Gadus macrocephalus Theragra chalcogramma Gadidae Chrysanthemum morifolium Chrysanthemum indicum Compositae
176 166 R R Notopterygium incisum Notopterygium forbesii Umbelliferae
177 167 Evodia rutaecarpa Evodia officinalis Evodia bodinieri Rutaceae Arctium lappa écompositae R
178 168 Gardenia jasminoides Rubiaceae A A W A A W Zizyphus jujuba spinosa Rhamnaceae R
179 169 R R A A W A A W Magnolia salicifolia Magnolia kobus Magnolia biondii Magnolia sprengeri Magnolia denudata Magnoliaceae R
180 170 R Cassia angustifolia Cassia acutifolia Leguminosae R A A A A W W A A A A W W n
181 171 R A A A A W W A A A A W W n R
182 172 R R A A W A A W
183 173 R A A W A A W R Uncaria rhynchophylla Uncaria sinensis Uncaria macrophylla Rubiaceae
184 174 A A A W AA A W Gastrodia elata Orchidaceae R
185 175 Asparagus cochinchinensis Liliaceae R Eucommia ulmoides Eucommiaceae Fritillaria verticillata thunbergii Liliaceae R
186 176 R Eriobotrya japonica Rosaceae R
187 177 R Cannabis sativa écannabidaceae R
188 178 R Q Q W Q Q W Q Q W Q Q W R Alpinia officinarum Zingiberaceae
189 179 R R
190
191
192 183
193
194 185
195 186
196 187
197 188
198 189
199 190
200 191
201 192
202 193
203 194
204 195
205 196
206 197
207 198
208 199
209 200
210 201
211 202
212 203
213 204
214 205
215
216
217 209
218 210
219 211
220 212
221 213
222 214
223 215
224 216
225 217
226 218
227 219
228 220
229 221
230 222
231 223
232 224
233 225
234 226
235 227
236 228
237
238 231
239 232
240 233 Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus Candida albicans Aspergillus niger C. albicans A. niger A. niger A. niger
241 234
242 235 N N N N
243 236
244 237 R M R R M R
245 238 N N N N
246 239 N N N N
247 240
248 241
249 242
250 243
251 244
252 245
253 246
254 247 γ
255 248
256 249
257 250
258 251 R R VT VT R V TV T
259 252
260 253
261 254
262 255
263
264 259
265
266 p p 107
267 264 p 107 p α 9 β p p p p m N n 109 t m
268 α 110 α l
269 N N
270 n 113 H N p
271 n p 116 p
272 n p l 302 l
273 N N p o
274 dl dl 120 dl 383 dl 383 dl p 120 p 120 p n
275 n n
276 µ 122 µ 122 µ m n β 834 β
277 d d dl n p 124
278 o n n
279 β m γ p 127 p d p p
280
281 dl α n
282
283 N N 135 N N N N 135 N N N 135 N N N 135 N N N N N 136 N N 136 N N
284 p 137 p m m m aa n 139 t t N 139 N p 139 N 139 N 139 N p 139 N p N N N N p p
285 p p p 139 p 139 p p p p 140 p N N n N N p N N 140 N N n 141 n 141 n 141 n 12 n 141 n N N 142 N N 142
286 283 N N
287
288 p
289
290 ~ µ~ 149 µ~ 149 µ~
291 N N op 151 pp 151 pp 151 pp
292 dl l
293 N N N N N N p dl α
294 H 156 H o o 157 p p 157 p
295 α N 157 α α α 157 p 157 α 157 p dl α p p p p α α o 159 o o p 159 p p
296 α α
297 O
298 α α γ γ 163 δ δ N N p 164 m H 13 N N 164 d cis H 164 d cis p H N 165 p
299 α p 166 p o o
300 o p n o n n 169 t tert
301 N t α α 233 α n
302 N 171 N N 172 N p p p
303 n 173 n p N α 175 N α 175 N α 175 N α p 175 p
304 d
305
306 dl 382 dl H 180 H 14 H N α O N N dl 981 l 982 l
307 N 182 N 182 N 182 N
308 N N 185 N N
309 n p p
310 n n 188
311
第十四改正日本薬局方第二追補
461 3 3 3 5 5 6 6 10 18 19 79 81 101 113 127 133 139 145 147 152 153 156 158 165 3 19 20 21 22 22 23 24 25 26 26 27 28 29 29 30 31 dl 32 dl 33 34 34 36 36 37 38 38 38 39 40 42 42 42 43 44 45 46 46 47 48
第十五改正日本薬局方第一追補
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公開情報 2016 年 1 月 ~12 月年報 院内感染対策サーベイランス集中治療室部門 3. 感染症発生率感染症発生件数の合計は 981 件であった 人工呼吸器関連肺炎の発生率が 1.5 件 / 1,000 患者 日 (499 件 ) と最も多く 次いでカテーテル関連血流感染症が 0.8 件 /
公開情報 2016 年 1 月 ~12 月年報 院内感染対策サーベイランス集中治療室部門 集中治療室(ICU) 部門におけるサーベイランスの概要と目的 本サーベイランスの目的は 集中治療室 (Intensive Care Unit : ICU) における人工呼吸器関連肺炎 尿路感染症 カテーテル関連血流感染症の発生状況 * を明らかにすることである 集計対象医療機関の各感染症発生率を 1,000 患者
４月号 学会特集号 １２２２４７／１６）一般演題目次
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物理化学I-第12回(13).ppt
I- 12-1 11 11.1 2Mg(s) + O 2 (g) 2MgO(s) [Mg 2+ O 2 ] Zn(s) + Cu 2+ (aq) Zn 2+ (aq) + Cu(s) - 2Mg(s) 2Mg 2+ (s) + 4e +) O 2 (g) + 4e 2O 2 (s) 2Mg(s) + O 2 (g) 2MgO(s) Zn(s) Zn 2+ (aq) + 2e +) Cu 2+ (aq)
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物理化学I-第11回(13).ppt
I- 11-1 10 10.5 H 3 O + (aq) + OH (aq) + Na + (aq) + Cl (aq) Na + (aq) + Cl (aq) + 2H 2 O(l) - or - [A] V A = [B] V B 22 mol dm 3 equiv dm 3 - H 2 SO 4 (aq) + 2NaOH(aq) 2Na + (aq) + SO 4 2 (aq) + 2H 2
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119-0912.pdf 1 1 2 日本薬局方収載生薬の学名表記について 日本薬局方の学名表記と分類学的に用いられる学名表記 生薬名アカメガシワアセンヤクアマチャアラビアゴムアロエアンソッコウイレイセンインチンコウインヨウカクウイキョウウイキョウ油 日本薬局方の学名表記 = 分類学的に用いられている学名表記 ( 組合わせ明記 命名者簡略標準化 ) 日本薬局方の学名表記とは異なるが分類学的に同一あるいは同一とみなされる
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第4次酸性雨全国調査報告書(平成16年度) -(Ⅱ)付表編-
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