A 10:00-11: :00 A-01 orexin-a orexin 10:12 A-02 allopregnanolone , :24 A-03 neovibsanin core structure (NVC) TrkB

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2 A 10:00-11: :00 A-01 orexin-a orexin 10:12 A-02 allopregnanolone , :24 A-03 neovibsanin core structure (NVC) TrkB :36 A-04 SV2A 1, :48 A-05 de novo POGZ ips 1 1 1,2 1, ,4 5 5,6 4,5 1,4,7, :00 A ,2 1 2,3 1,3,4,

3 A 11:12-12: :12 A-07 D :24 A-08 11:36 A :48 A-10 Higor A. Iha 12:00 A-11 : D NPO J-DO 12:12 A-12 :

4 A 13:55-14: :55 A-13 SphK2/S1P 14:07 A-14 HMGB :19 A-15 HMGB1 IL-1β :31 A-16 HMGB :43 A-17 TRPV4 LPS IL10 15

5 A 15:00-16: :00 A-18 RNF182 mtorc1 15:12 A-19 ips 1 1,2 1,3 1 3,4 1,4,5, :24 A-20 GPR3 15:36 A-21 D2 DP1 1 1, ,4 3 1,2,5, :48 A-22 1,2 1,2, :00 A-23 T Ca 2+ 6-prenylnaringenin CB1 NG Nguyen Huy Du ,5 1,

6 A 16:17-17: :17 A-24 Proflavine K + (Kir) 16:29 A-25 Kir4.1 BDNF 16:41 A-26 16:53 A-27 β milk fat globule EGF factor 8 protein :05 A-28 P2Y :17 A-29 peroxiredoxin SOD1 (G93A) A :29 A-30 Cyclophosphamide H2S/Cav3.2 :NF-κB

7 B 10:00-11:12 10:00 B-01 IgE :12 B-02 (SCIT) Breg :24 B-03 FTY ICT 10:36 B-04 AGEs :48 B-05 TCR formin 11:00 B-06 Lysophosphatidic acid induces Filaggrin expression and promotes skin barrier function in human keratinocyte Ratklao Siriwach, Akiko Sumitomo, Kentaro Ito, Kohei Tanabe, Dean Thumkeo, Shuh Narumiya Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine 18

8 B 11:12-12: :12 B-07 GPR40/FFAR1 11:24 B-08 p62 APP ¹ ² ³ ² ¹ ² ³ 11:36 B :48 B-10 Expression of MHCI in astrocytes leads to impairments in a visual discrimination task in mice Bolati Wulaer, Akira Sobue, Norimichi Itoh, Taku Nagai, Kiyofumi Yamada Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine 12:00 B-11 19

9 B 13:55-15:07 13:55 B-12 CCL6 14:07 B-13 HSP90 MAPK 14:19 B-14 Pumilio Puf Dieter A. Wolf Sanford Burnham Prebys Medical Discovery Institute 14:31 B-15 1,2 EGF :43 B :55 B-17 Kir2.1 20

10 B 15:12-16:12 15:12 B-18 Dad , :24 B , :36 B-20 N- (OGT) GSK-3β O-GlcNAc , 2 15:48 B-21 TMEM16A 16:00 B-22 21

11 B 16:17-17:41 16:17 B-23 herg : II 3 16:29 B-24 ips CRISPRi :41 B ,2 1,3 1 1, :53 B-26 R-spondin , :05 B-27 NCX1 1,2 2 2, :17 B-28 PAR :29 B-29 cgmp 22

12 C 10:00-11:12 10:00 C :12 C , :24 C-03 Non-Competitive LAT1 inhibitors suppress mtorc1 signaling similarity to competitive LAT1 inhibitors Pornparn Kongpracha 1,2, Suguru Okuda 2, Ryuichi Ohgaki 2, Yoshikatsu Kanai 2, Shushi Nagamori 1,2 1 Laboratoy of Biomolecular Dynamics, Department of Collaborative Research, Nara Medical University, 2 Department of Bio-system Pharmacology, Graduate School of Medicine, Osaka University 10:36 C-04 α 1 1,2 1,2 1,2 1,2 1,3 1 1,3 5 1,3 1,2 1, RI 5 10:48 C-05 TRKB is a potential therapeutic target for poorly-differentiated oral squamous cell carcinoma Kazumasa Moriwaki 1, Yusuke Ayani 2, Hiroko Kuwabara 3, Shuji Ohomura 2, Tetsuya Terada 2, Ryo Kawata 2, and Michio Asahi 1 1 Dept. Pharmacology, Med., Osaka Medical College, 2 Dept. Otorhinolaryngology, Med., Osaka Medical College, 3 Dept. Pathology, Med., Osaka Medical College 11:00 C-06 Augmented O-GlcNAcylation Alleviates Inflammation-mediated Colon Carcinogenesis via Suppression of Acute Inflammation

13 C 11:12-12:24 11:12 C , , , :24 C , :36 C-09 galectin-3 11:48 C-10 LAT1 in endothelial cells as a novel target of anti-angiogenic cancer therapy Lili Quan 1 Ryuichi Ohgaki 1 Suguru Okuda 1 Shushi Nagaori 1, Yoshikatsu Kanai :00 C-11 Protein degradation of KCa1.1 K + channel by androgen receptor inhibition in breast cancer cells Anowara Khatun , :12 C-12 Critical moieties of aromatic amino acid for renal accumulation of tumor imaging probes Chunhuan Jin 1, Ling Wei 1, Ryuichi Ohgaki 1, Hideyuki Tominaga 2, Suguru Okuda 1, Shushi Nagamori 1, Yoshikatsu Kanai

14 C 13:55-15:07 13:55 C-13 PGE2-EP2/EP4 Th17 Jinju Lee 1 1 Dean Thumkeo 1,2 1,2 1 Alliance Laboratory for Advanced Medical Research, Kyoto University Graduate School of Medicine, 2 Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine 14:07 C :19 C-15 ( ) :31 C :43 C-17 NOX1/NADPH 14:55 C-18 OASIS ,

15 C 15:12-16:12 15:12 C-19 15:24 C :36 C-21 S- 15:48 C :00 C-23 mtor 26

16 C 16:17-17:41 16:17 C-24 16:29 C-25 Histidine-rich glycoprotein(hrg) :41 C :53 C-27 17:05 C-28 Guan Yu Zhang Yifan 17:17 C-29 1, :29 C-30 sitagliptin

17 28

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