明海大学歯学雑誌 37‐2/1.秦泉寺

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1 J Meikai Dent Med 37, , ml /1 min Wong-Baker Face Rating Scale FS g 3 5ml /1 min, FS ml /1 min FS g 3 6ml /1 min, FS 3 Two Cases of Xerostomia that Showed an Improvement after Being Treated with Chinese Herbal Medicine Kazumasa MORI, Hiroyuki ONUKI, Aya YOSHIDA, Nozomi TAMURA, Yuya MAEKAWA, Chie KONNO, Satori IIDA and Jun SHIMADA Division of Oral and Maxillofacial Surgery, Department of Diagnostic & Therapeutic Sciences, Meikai University School of Dentistry Abstract : Case 1 was a 7-year-old male who visited our hospital complaining of oral dryness and difficulty in eating. The oral findings included reddening and tongue coating on the dorsum of the tongue. The patient complained of a strong tingling sensation that made it difficult to ingest meals. The patient had a history of disorders including hypertension and diabetes, and he was also taking hypotensors. The gum test result was 5 ml /1 min. The Wong-Baker Face Rating Scale FSwas 5 points. The patient was diagnosed to have glossitis caused by xerostomia. For the treatment, 9. g a day divided into three doses of Byakkokaninjinto was administered for two months. After two months of administering Chinese herbal medication, the gum test result was 5 ml /1 min and the FS score was 1 points. The findings of glossitis had largely disappeared and the subjective symptoms were found to have decreased. There was no significant change in the amount of saliva, but the clinical findings had improved for the tongue, while the subjective symptoms also showed improvement. Case was a 66-year-old female who visited our hospital complaining of oral dryness. The patient complained that she could not stop coughing when the sensation of oral dryness became strong at night. The oral findings revealed no particular organic changes. There were no specific findings in the patient s medical history. The gum test result was 6 ml /1 min. The FS score was 5 points. The patient was diagnosed to have xerostomia and we therefore administered 9. g a day divided into three doses of Bakumondoto for two months. After two months of administering Chinese herbal medicine, the gum test re-

2 15 37, 8 sult was 6 ml /1 min and the FS score was 3 points. The sensation of oral dryness during the daytime had mostly disappeared and the patient s coughing at night also decreased. In addition, no improvement were observed in the amount of saliva, however, the clinical symptoms did indicate some degree of improvement. The herbal treatment was useful for alleviating thirst and oral dryness in two cases, but cases showed a slower increase in salivary production. Key words : xerostomia, Chinese herbal medicine, Byakkokaninjinto, Bakumondoto QOL Ca Fig 1 SS-A Fig 1 Case 1 : Clinical appearance of intraoral view at the first visit. SS-B RA 5 ml /1 min 1! Wong-Baker Face Rating Scale FS g 3 FS 3 5ml /1 min FS 1

3 155 Fig 1 6g, 6 6ml /1 min Fig Case 1 : Clinical appearance of intraoral view after two months. Fig Fig SS-A SS-B RA 6 ml /1 min FS lingual plicate 5 reddening tingling sensation treatment 3 1 Hachi Azule collutorium Byakkokaninjinto 9. g a day divided into three doses months 6. g a day divided into three doses months amount of saliva ml/1 min first visit weeks 1 month month month 6 month Fig 3 Case 1 : Clinical symptoms and treatment.

4 156 37, 8 1! 1 1 9g 3 FS 5 6ml /1 min FS 3 7ml /1 min Fig FS 6 8 Fig Case : Clinical appearance of intraoral view at the first visit. Fig 5 Case : Clinical appearance of intraoral view after four months. FS edema of hand and foot 5 cough oral dryness treatment 3 1 Hachi Azule collutorium Bakumondoto 9. g a day divided into three doses months amount of saliva ml/1 min first visit weeks 1 month month month 6 month Fig 6 Case : Clinical symptoms and treatment.

5 157 ml /1 min Fig , 3 5 6, 7 8! 1 5ml /1 min Ca 1 mg/dl oxybutynin hydrochloride 1 6 5ml /1 min 6ml / 1 min FS 5 88 mg/dl Fig ml /1 min

6 158 37, 8! 6 ml /1 min Fig , 73 76, 5, 8 5, , 51 55, 7 11, , , 1, , 77 8, 13, , In pp , 7 In pp7 8, 7 Oxybutynin hydrochloride 8, 19 9, 199 Bakumondo-to 7, 895 9,

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