36:378 第 38 回日本脳卒中学会講演シンポジウム 原著 36: , 要旨 TIA 2 t-pa Key words: stroke registry, stroke subtype, onset-visi

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1 36:378 第 38 回日本脳卒中学会講演シンポジウム 原著 36: , 要旨 TIA 2 t-pa Key words: stroke registry, stroke subtype, onset-visit time, chronological change はじめに Japan Standard Stroke Registry Study Group JSSRS group 対象と方法 , ± I II III 3 χ 2 SPSS 18.0 結果 TIA

2 36:379 Fig Fig. 1 TIA Fig. 2 I 25 III 28 I 13 II 15 III Fig I 7 II 6 III 5 Fig. 3

3 36:380 脳卒中 36 巻 5 号 (2014:9) Fig. 3 Fig. 4 2 (Fig. 4) 7 (79,707 ) 2 ( 53 ) (52 ) AVM (46 ) (45 ) TIA(44 ) (2 14 ) (Fig. 5) 2 TIA II III 3 NIHSS (Fig. 6) 23 25

4 36:381 Fig. 5 2 Fig TIA TIA TIA I III 4 23 Fig. 7 4 modified Rankin Scale mrs Fig. 8 TIA mrs 2

5 36:382 脳卒中 36 巻 5 号 (2014:9) Fig. 7 Fig. 8 ADL

6 36: mrs mrs 2 40 mrs 5 32 mrs 2 32 mrs 5 38 mrs 2 51 mrs 5 33 TIA mrs 2 I 52 III 57 mrs 5 I 16 III 12 考案 ,000 63, , J-MUSIC Fukuoka Stroke Registry J-MUSIC 5 Fukuoka Stroke Registry BAT 7 AVM TIA t-pa t-pa t-pa t-pa 参考文献

7 36:384 脳卒中 36 巻 5 号 (2014:9) ) ( ): ) ( ): )Kimura K, Kazui S, Minematsu K, et al: Analysis of 16,922 patients with acute ischemic stroke and transient ischemic attack in Japan. A hospital-based prospective registration study. Cerebrovasc Dis 18: 47 56, ) : (Fukuoka Stroke Registry; FSR) 102: , )Toyoda K, Yasaka M, Iwade K, et al: Dual antithrombotic therapy increases severe bleeding events in patients with stroke and cardiovascular disease: a prospective, multicenter, observational study. Stroke 39: , )Adams HP, del Zoppo G, Alberts MJ, et al: Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke 38: , )Johnsen SP, Svendsen ML, Hansen ML, et al: Preadmission oral anticoagulant treatment and clinical outcome among patients hospitalized with acute stroke and atrial fibrillation: a nationwide study. Stroke 45: , 2014 Abstract Epidemiology of acute stroke in Japan: Japan Standard Stroke Registry Study Shuhei Yamaguchi, M.D., Ph.D. 1) and Shotai Kobayashi, M.D., Ph.D. 2) 1) Department of Neurology, Faculty of Medicine, Shimane University 2) Shimane University Background: Stroke is still a heavy burden to our society. We have developed a stroke databank system since 1999 to standardize stroke therapy in acute stage and verify the evidence of treatment in Japanese stroke patients. Methods: We analyzed the data of more than 100,000 patients with acute stroke registered in Japan Standard Stroke Registry from 1999 to We focused on the chronological changes in stroke patient data. Results: Ischemic stroke was divided into three subtypes; 31% of patients had atherosclerotic, 29% had lacunar stroke, and 26% had cardioembolic stroke. Only the prevalence of cardioembolic stroke increased over the years. The incidence of cardioembolic stroke was high in aged people; 30% of stroke patients of more than 80 years had cardioembolic stroke. The time interval between stroke onset and hospital visit did not change chronologically except for transient ischemic attack, which showed increased ratio of early visit within 2 hours after stroke onset. The severity of illness became milder in recent years for ischemic stroke, but not for hemorrhagic stroke. On the other hand, modified Rankin Scale at discharge improved only for atherosclerotic stroke in recent years, while other types of stroke did not show improvement in prognosis at discharge. Conclusion: These data indicate the importance for prevention of cardioembolic stroke in aged people and social education for early detection of stroke symptoms and hospital visit. Key words: stroke registry, stroke subtype, onset-visit time, chronological change (Jpn J Stroke 36: )

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