Vol.16 No.2 July 2012 報 告 パーキンソン病の歩行障害症状に変化をもたらすリズム刺激の方法および選曲等の嗜好反映の影響 音楽療法実践についての文献レビュー 1) 稲井晴子 抄 録 目的 方法 A B Web Version5.0 PubMed PsycINF

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1 報 告 パーキンソン病の歩行障害症状に変化をもたらすリズム刺激の方法および選曲等の嗜好反映の影響 音楽療法実践についての文献レビュー 1) 稲井晴子 抄 録 目的 方法 AB Web Version5.0PubMedPsycINFOMEDLINECINAHLThe Cochrane Library ABUPDRS 分析 m/ cm/ / UPDRS 結果 109 RCT RCT UPDRS UPDRS p 0.05 結論 キーワード : Ⅰ. はじめに

2 1040 Thaut p 0.05 p Lim 2005 Jiang A C 2011 Davis et al., Ⅲ. 研究方法 1. 文献検索 Web Version5.0 WebPubMed, PsycINFO, MEDLINE, CINAHL, The Cochrane Library /Music TherapyAND /Parkinson Disease Web PubMed, PsycINFO, MEDLINE, CINAHL, The Cochrane Library journal article, book, review, news n 2. 文献の分析 m/ cm/ / Unified Parkinsons Disease Rating Scale UPDRS UP- DRS 14 on Ⅳ. 結果 Ⅱ. 研究目的 1. 文献検索結果 51PubMed PsycINFO - 2 -

3 ス 誌 51 論文 論文 学 論文 17 5 論文 39 リ 図 1 文献検索と抽出 MEDLINE23CINAHL15The Cochrane Library Clinical Trial a2005b a Randomized Control Trial RCT Pacchetti et al., 2000 counterbalanced repeated measure design Brown et al., 2009 RCT 文献の分析結果 1) リズム刺激の方法と歩行障害の変化 1120 / a 2005b32001 Pacchetti et al., 2000Brown et al., UPDRS p 提供されるリズム刺激と歩調の相違からみた歩行速度の変化 RCT a a a - 3 -

4 表 1 音楽療法の対象者, 音楽療法の内容, および歩行症状変化の概要 / / / 2005a % 100 / 100 / 10% 6 10% 100 / 10% 2005b 7 10% 10% / CD 120 / CD CD 120 / * CD Pacchetti et al RCT 10.OT. Brown et al RCT 11 10m, * 2004Brown et al2009 * CD120 / 2005 CD Not Significant - 4 -

5 * UPDRS n Hoehn and Yahr p % UPDRS all n p % UPDRS / p % p % % n / 12.3% 11.8% 11.0% p % 19.1% p % 0.0% 11.4% p % n / p % p % 0.0% p % p % 1.1% n / % % % n / 20.7% 11.7% 7.1% n / vs p vs 9.7% vs 1.7% 11.3% vs 11.5% UPDRS all UPDRS bradykinesia n16 vs vs vs / p % vs % p % vs % n 10 vs vs /!! - 5 -

6 / 120 / SD / a 2 提供されるリズム刺激と歩調の相違からみた歩幅の変化 RCT a a a / 120 / SD / a / b8.9 3 提供されるリズム刺激と歩調の相違からみた歩調の変化 a a a 118SD / a 85SD / 2005a 4リズム刺激による UPDRS 第三部スコアの変化 RCT Pacchetti et al., 2000 UPDRS p UPDRS ) 嗜好反映による歩行障害の数値的変化 a2005bPacchetti et al., 2000Brown et al., 2009 Pacchetti et al., 2000 UPDRS Ⅴ. 考察 1. 歩行障害に変化をもたらすリズム刺激方法 1 提供されるリズム刺激と歩調の相違からみた歩行速度の変化 2 提供されるリズム刺激と歩調の相違からみた歩幅の変化 p Thaut 提供されるリズム刺激と歩調の相違からみた歩調の変化 - 6 -

7 4リズム刺激による UPDRS 第三部スコアの変化 / steps/min p a2005b 100 / / / b / Pastor et al., p Thaut Jiang 2006 RCTBrown et al, 選曲等に本人の嗜好をとりいれることの歩行障害症状への影響 Pacchetti 2000 Blood et al., 2001 Menon et al., 2005 Ⅵ. 研究の限界 5070Hoehn and Yahr 20 Hoehn and Yahr RCT 謝辞 - 7 -

8 引用文献 2008 CD, : Blood, A. J., Zatorre, R. J.2001 Intensely pleasurable responses to music correlate with activity in brain regions implicated in reward and emotion., The National Academy of Sciences, Brown, L.A., de Bruin N & Doan, J.B., et al.2009 Novel challenges to gait in Parkinsons disease: the effect of concurrent music in single- and dual-task contexts., Archives Of Physical Medicine And Rehabilitation, Davis, W. B., Thaut, M. H., Gfeller, K. E , , Jiang, Y., Norman, K. E.2006Effects of visual and auditory cues on gait initiation in people with Parkinsons disease., Clinical Rehabilitation, 20, : Lim, I., Van,W. E. & Goede, C. et al.2005effects of external rhythmical cueing on gait in patients with Parkinsons disease: a systematic review., Clinical Rehabilitation, 19, , Menon, V., Levitin, D. J.2005The rewards of music listening: response and physiological connectivity of the mesolimbic system., Neuroimage, 28, a b http:// http:// Pacchetti, C., Mancini, F., Aglieri, R. & Fundarò, C. et al.2000active music therapy in Parkinsons disease: an integrative method for motor and emotional rehabilitation., Psychosom Med, Pastor, M. A., Artieda, J., JahanshahiI, M. et al. 1992Time estimation and reproduction is abnormal in Parkinsons disease., Brain, Thaut, M.H., McIntosh, G.C. & Rice, R.R. et al. 1996Rhythmic Auditory Stimulation in Gait Training for Parkinsons Disease Patients., Movement Disorders,

9 英文抄録 Rhythmic Stimulation Reflecting Individual Preference in Generating a Gait Change in Patients with Parkinson s Disease Gait Disorder : Review of the Literature on Music Therapies Haruko Inai 1) National Center of Neurology and Psychiatry ObjectiveTo find, appropriate methods of rhythmic auditory stimulationrsand the advantage of reflecting individual preference, to generate changes in patients with Parkinsons disease gait disorder GDusing music therapies MTapproach. MethodAn electronic literature search used databases: Ichushi Web, PubMed, PsycINFO, MEDLINE, CI- NAHL, and the Cochrane Library from 2000 to Inclusion criteria were: amt programs including RS and bmt results including scores of: velocity, stride length, step cadence or/and Unified Parkinsons Disease Rating Scale Part 3 UPDRS 3measured before and after intervention. 109 articles were extracted and eight met the criteria. AnalysisData were drawn from two RCTs including two case-studiesand six before-after studies BAS including nine case-studies. Analyzed were the relationships between the before usual stepsand after RS changes in scores. Results1Improvement of velocity was found in four BAS cases, which provided RS fasterthan patients usual steps per minutes ROC: Increase of stride length was found in four BAS cases, which provided RS fasterthan usual steps Decrease of cadence was found in one BAS case, which provided RS slowerthan usual steps It was also found in two BAS cases, which provided RS the sameas usual steps Decrease of UPDRS total score was found in one RCT 9.7and one BAS case There was also a gait score decrease of UPDRS in BAS Studies that reported significant change p 0.05on scores reflected patientspreference. Conclusion1Deciding tempos of RS based on patients usual steps is needed to generate changes in GD. In addition, fastertempos tend to increase the velocity and stride length and slowertempos tend to decrease of cadence. Rhythmical music tends to generate changes of motor examination skill including GD. 2MT programs meeting the patientsindividual preference tends to generate changes in GD. Keywords:Parkinsons diseasemusic therapygait disorder - 9 -

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