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1 4 1 13 1 4 6 7 2012

7 27 12 50 13 40 1 7 27 13 40 14 30 1 7 28 13 20 14 10 1 Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode Charles L. Bowden University of Texas Health Science Center, School of Medicine, San Antonio, Texas 7 28 11 10 12 00 1 CNS 7 28 11 10 12 00 2 B The 9th Congress of the Japanese Society of Mood Disorders 21

7 28 11 10 12 00 3 C 7 28 13 20 14 10 4 A 22 The 9th Congress of the Japanese Society of Mood Disorders

7 27 9 30 11 30 1 S1-1 S1-2 S1-3 S1-4 7 27 9 30 11 30 2 B 4 S2-1 S2-2 The 9th Congress of the Japanese Society of Mood Disorders 23

S2-3 S2-4 7 27 9 30 11 30 3 C S3-1 JFE S3-2 S3-3 S3-4 24 The 9th Congress of the Japanese Society of Mood Disorders

BPD 7 27 9 30 11 30 4 A BPD BPD BPD DSM5 Dialectical Behavior Therapy Transference Focused Psychotherapy BPD S4-1 BPD S4-2 BPD DBT S4-3 BPD S4-4 7 27 14 40 16 40 1 S5-1 S5-2 The 9th Congress of the Japanese Society of Mood Disorders 25

S5-3 S5-4 S5-5 7 27 14 40 16 40 2 B 1 2 S6-1 S6-2 S6-3 S6-4 26 The 9th Congress of the Japanese Society of Mood Disorders

7 27 14 40 16 40 3 C S7-1 S7-2 ADHD S7-3 S7-4 7 28 9 00 11 00 1 75comorbidity SSRI S8-1 The 9th Congress of the Japanese Society of Mood Disorders 27

S8-2 S8-3 S8-4 7 28 9 00 11 00 2 B NTT NTT S9-1 S9-2 S9-3 S9-4 NPO S9-5 PIPC Psychiatry in Primary Care in 2010 2012 28 The 9th Congress of the Japanese Society of Mood Disorders

7 28 9 00 11 00 3 C S10-1 S10-2 S10-3 S10-4 Lewy 7 28 9 00 11 00 4 A 4 S11-1 S11-2 S11-3 The 9th Congress of the Japanese Society of Mood Disorders 29

S11-4 7 28 14 20 16 20 1 S12-1 S12-2 S12-3 S12-4 7 28 14 20 16 20 2 B 5 10 20 S13-1 30 The 9th Congress of the Japanese Society of Mood Disorders

S13-2 S13-3 12 S13-4 S13-5 The 9th Congress of the Japanese Society of Mood Disorders 31

7 27 17 50 19 20 1 heterogeneous mrna WS1-1 WS1-2 WS1-3 WS1-4 mrna 7 27 17 50 19 20 2 B " " WS2-1 WS2-2 WS2-3 32 The 9th Congress of the Japanese Society of Mood Disorders

7 27 17 50 19 20 3 C 1 - - WS3-1 WS3-2 WS3-3 7 27 17 50 19 20 4 A WS4-1 WS4-2 WS4-3 The 9th Congress of the Japanese Society of Mood Disorders 33

7 28 14 50 16 20 5 C 7 28 14 20 16 20 3 C 30% 10 J Clin Psychiatry 64,2 p161-74,2003 7.8 Bipolar Disord. 2003 5: 169-79 BS-1 BS-2 BS-3 BS-4 34 The 9th Congress of the Japanese Society of Mood Disorders

7 27 14 40 16 40 4 A CS-1 CS-2 CS-3 7 28 14 20 16 20 4 A 2006 2007 2012 The 9th Congress of the Japanese Society of Mood Disorders 35

JS-1 JS-2 JS-3 JS-4 JS-5 J-MISP Group 7 28 9 00 14 00 5 C 5 30 + 10 15 3 30 12,000 6 3 36 The 9th Congress of the Japanese Society of Mood Disorders

1 30 50 / 2 3 25 7 28 11 10 12 00 4 A 7 28 11 10 12 00 4 A Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins The 9th Congress of the Japanese Society of Mood Disorders 37

1 3 1 8 1 3

7 27 8 30 9 20 2 B / 7 27 8 30 9 20 3 C MSD 7 27 8 30 9 20 4 A 7 27 11 40 12 40 1 Treatment strategies to prevent mood episodes and optimize outcomes in bipolar disorder Charles L. Bowden The University of Texas Health Science Center, School of Medicine, San Antonio, Texas The 9th Congress of the Japanese Society of Mood Disorders 41

7 27 11 40 12 40 2 B Meiji Seika 7 27 11 40 12 40 3 C 7 27 11 40 12 40 4 A Heterogeneous!? / / 7 28 12 10 13 10 1 7 28 12 10 13 10 2 B 42 The 9th Congress of the Japanese Society of Mood Disorders

7 28 12 10 13 10 3 C / 7 28 12 10 13 10 4 A 7 27 16 50 17 40 2 B 7 27 16 50 17 40 3 C 7 27 16 50 17 40 4 A The 9th Congress of the Japanese Society of Mood Disorders 43

7 28 17 30 19 30 1 5 9 / 13 JCPTD 9 550 9 9 7 27 7:30 100 100 44 The 9th Congress of the Japanese Society of Mood Disorders

1. P1-1 1 2 1,2 1 2 P1-2 P1-3 1 2 2 1 2 P1-4 1 1 1 1,2 1 1 3 1 1 1 2 3 P1-5 Duloxetine OlanzapineMADRS 2 6.9 31 P1-6 P1-7 22 P1-8 1 2 1 1 2 P1-9 2 The 9th Congress of the Japanese Society of Mood Disorders 47

P1-10 1 2 3 1 2 3 P1-11 SSRI P1-12 escitalopram 1,2 3 2 2 1 2 3 P1-13 The Bcl1 polymorphism of glucocorticoid receptor gene and response to milnacipran and fluvoxamine in depressed patients 1 2 3 4 5 1 12 3 45 P1-14 P1-15 1 P1-16 Lamotrigine Stevens-Johnson P1-17 1 1 1 1,2 1 1 2 48 The 9th Congress of the Japanese Society of Mood Disorders

2. P2-1 1,2 3 1 2 3 P2-2 1 P2-3 1 2 3,4 3,4 1 2 3 4 P2-4 ; 118 1 1 1 2 1 1 2 FK P2-5 1,2 1,2 2 1 2 P2-6 P2-7 1 2 3 1 2 3 P2-8 1 1 1 1 2 12 P2-9 The 9th Congress of the Japanese Society of Mood Disorders 49

P2-10 P2-11 1,2 1 1 1 1 1 1 2 P2-12 1 1,2 1 1 1 1 1 1 1 1 1 1 2 P2-13 1,2 3 3,4 5,6 7 7 8 1 2 3 4 5 6 7 8 P2-14 1 2 3 1 2 3 P2-15 1 2 2,3 5 6 2,4 1 2 NPO 3 45 6 P2-16 2 2 1 2 50 The 9th Congress of the Japanese Society of Mood Disorders

3. P3-1 1,3 2 3 4 1 2 34 P3-2 HPA 1 1 1 1 1 2 1 1 2 P3-3 P3-4 1 2 1 2 P3-5 P3-6 1 2,3 1 2 J 3 P3-7 P3-8 fmri 1,2,3 Jeffrey Miller 1 Ramin Parsey 1 1 2 3 The 9th Congress of the Japanese Society of Mood Disorders 51

P3-9 BDNF 1 2 2 2 3 2 2 1 2 1 12 3 P3-10 HAM-D 1 2 2 2 1 3 2 2 2 1 12 3 P3-11 P3-12 NIRS P3-13 NIRS 1 P3-14 NIRS 2 P3-15 1 2 3 3 12 3 P3-16 CogStateQOL 1,2 2 1 3 1 1 1 1 1 1 1 1 1 1 2 1 2 3 P3-17 TEMPS-A/MPT 1 1 1,2 1 1,3 1 1 2 3 52 The 9th Congress of the Japanese Society of Mood Disorders

P3-18 DSM-4 P3-19 P3-20 P3-21 1,2 2 2 2 2 2 2 2 2 12 P3-22 1 3 1,2 1,2 1,2 1 1,2 1,2 1,2 1,2 1,2 2 1 Juntendo University Mood Disorder Project JUMP 23 P3-23 1 2 1 2 P3-24 P3-25 1 1 1 1 1 1 2 2 1 1 2 P3-26 1 1 1 1 1 1 1 2 2 1 1 2 The 9th Congress of the Japanese Society of Mood Disorders 53

P3-27 NIDS P3-28 1,4,5 1 2 1 3 3 1 2 3 4 5 P3-29 TEMPS-A P3-30 TCI 1 1,2 1,3 1 1 1 2 3 P3-31 1 2 2 3 2 1 2 3 4. P4-1 1 2 3 1 23 P4-2 1 2 2 2 1 1 1,2 1 2 P4-3 CDI 1 2 3 1 4 1 2 3 54 The 9th Congress of the Japanese Society of Mood Disorders

P4-4 BDNF 1 2 3 3 3 3 3 3 4 1 2 34 5. P5-1 P5-2 1 1 1 1 1 2 2 1 1 2 P5-3 1 1,2 1 1 1 1 2 P5-4 1 2 1 1 2 P5-5 P5-6 1 1 1 1 2 1 2 P5-7 1 1 1 2 1 2 The 9th Congress of the Japanese Society of Mood Disorders 55

6. P6-1 P6-2 QOL P6-3 P6-4 P6-5 1 Aleksic Branko 1 2 1 1 2 P6-6 1 2 2 1 1 1 1 2 NPO MDA-JAPAN P6-7 NIRS 1 2 3 4 1 2 3 4 P6-8 1,2 1 1 2 1 1 2 P6-9 EAP 2 1,2 3 1 1 2 NPO 3 56 The 9th Congress of the Japanese Society of Mood Disorders

P6-10 1,2 1 3 1 2 3 7. P7-1 EFT P7-2 1 1 2 2 3 3 4 4 5 6 1 2 3 4 5 6 P7-3 social skills training SST 1 1 1 1,2 1 1 1 2 P7-4 The 9th Congress of the Japanese Society of Mood Disorders 57