表 E スパイロメーター測定結果 ( 実測値 / 予測値 ) 肺活量 努力性 1 秒量 一秒率 中間 ピークフロー 50% 25% 症例 肺活量 呼気流量 肺活量流量肺活量流量 14 年度 / / / / /
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2 表 E スパイロメーター測定結果 ( 実測値 / 予測値 ) 肺活量 努力性 1 秒量 一秒率 中間 ピークフロー 50% 25% 症例 肺活量 呼気流量 肺活量流量肺活量流量 14 年度 / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / 年度 / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / 年度 / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / 年度 / / / / / / / / / / / / / / / / / / / / / / / /2.84 太字は予測値 ( 身長 年齢 体重からの ) の20% 以上の減少太字 20% には達しないが予測値より低値 -151-
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13 Exposure to Chemicals Physical response Individual Behavioral response Psychological Psychosocial response Stressor 1.Stressor before 2. Factors of 3. Psychosomatic interaction onset of MCS individual after occurrence of MCS differences amongs Understanding of idiopathic multiple chemical hypersensitivity ( as stress ti Subject Characteristics Group Patients Controls Number Sex Male 7 7 Female 8 29 Age Min.~Max. 23y.o.~42y.o. 21y.o.~48y.o. Mean±SD 34.3± ±6.6 Educataion University 9 13 College 2 9 High school 2 8 Student 2 6 Occupation (+) 9 21 (-) 6 15 Marriage (+) 7 20 (-)
14 Stressors before Onset of MCS Patients Controls Main Effect of Group Main Effect of Sex Interaction of Group x Sex Scale Mean SD Mean SD F p F p F p LHQ A. Life events Total stress scores during past one years N.S N.S N.S. Endurable highest stress scores N.S N.S N.S. B. Daily hassles N.S N.S N.S. LHQ; Life Health Questionnaire -163-
15 Factors of Individual Differences Patients Controls Main Effect of Group Main Effect of Sex Interaction of Group & Sex Scales Mean SD Mean SD F p F p F p EPQ-R Psychoticism (P) N.S N.S N.S. Extraversion/Introversion (E) N.S N.S N.S. Neuroticism (N) N.S N.S N.S. Lie scales (L) N.S N.S N.S. TAS-20R1 Difficulty identifying feelings N.S N.S N.S. 2 Difficulty describing feelings N.S N.S N.S. 3 Externally oriented thinking N.S N.S N.S. 4 Total N.S N.S N.S. SSAS Total N.S N.S. TAC-24 1 Getting information N.S N.S N.S. 2 Giving up N.S N.S N.S. 3 Positive interpretation N.S N.S N.S. 4 Plan drafting N.S N.S N.S. 5 Avoidance-like thinking N.S N.S N.S. 6 Distractive recreation N.S N.S N.S. 7 Catharsis N.S N.S. 8 Evading one's reponsibillity N.S N.S N.S. LHQ C. Stress coping skills f1.problem-focused coping N.S N.S f2.waiting-for-time-to-pass coping N.S N.S. f3.emotion-focused coping N.S N.S. D. Social support N.S N.S N.S. EPQ-R; Eysenck Personality Questionnaire Revised, TAS-20R; Toronto Alexithymia Scale, SSAS; Somatosensory Amplitude Scale TAC-24; Tri-Axial Coping Scale, LHQ; Life Health Questionnaire -164-
16 The Number of Subjects Having Smoking or Drinking Habit Category Patients Controls Male(n=7) Female(n=8) TOTAL(n=15) Male(n=6) Female(n=30) TOTAL(n=36) Smoking habits Before onset Drinking habits Before onset
17 Psychosomatic Interaction after Occurrence of MCS Patients Controls Main Effect of Group Main Effect of Sex Interaction of Group & Sex Scales Mean SD Mean SD F p F p F p CMI Physical symptoms A. Eyes and ears N.S N.S N.S. B. Respiratory system N.S N.S. C. Cardiovascular system N.S. D. Digestive tract N.S N.S N.S. E. Musculoskeletal system N.S N.S N.S. F. Skin N.S N.S N.S. G. Nervous system N.S N.S. H. Genitourinary system N.S N.S. I. Fatigability N.S N.S. J. Frequency of illness N.S N.S. K. Miscellaneous diseases N.S. L. Habits N.S N.S N.S. Total N.S N.S. Psychological symptomsm. Inadequacy N.S N.S N.S. N. Depression N.S N.S N.S. O. Anxiety N.S N.S N.S. P. Sensitivity N.S N.S N.S. Q. Anger N.S N.S N.S. R. Tension N.S N.S N.S. Total N.S N.S N.S. POMS Tension-Anxiety N.S N.S N.S. Depression N.S N.S N.S. Anger-Hostility N.S N.S N.S. Vigor N.S N.S. Fatigue N.S N.S N.S. Confusion N.S N.S N.S. LHQ A. Life events Present stress scores N.S N.S. Stress responses E. Behavioral change N.S N.S N.S. H. Psychological symptoms N.S N.S N.S. I. Physical symptoms N.S N.S N.S. CMI; Cornel Medical Index, POMS; Profile of Mood State, LHQ; Life Health Quesionnaire -166-
18 The Number of Subjects Having Psychiatric Diseases Category Patients Controls Male(n=7) Female(n=8)TOTAL(n=15) Male(n=6) Female(n=30)TOTAL(n=36) Anxiety Disorders TOTAL Present Agoraphobia without History of Panic Disorder Limited Symptom Panic Attack Panic Disorder With Agoraphobia Generalized Anxiety Disorder Social Phobia Obsessive-Compulsive Disorder Lifetime Panic Disorder Mood Disorders TOTAL Present Major Depressive Episode Melancholic Features S Dysthymic Disorder Major Depressive Episode Mood Disorder With Psychotic Disorder Lifetime Hypomanic Episode Manic Episode Major Depressive Episode Somatoform Disorders TOTAL Present Somatization Disorder Undifferntiated Somatoform Disorder
19 Heart Rate Variability Patients Controls Main Effect of Group Main Effect of Sex Interaction of Group & Sex Mean SD Mean SD F p F p F p HF/Total N.S N.S N.S. LF/HF N.S N.S. LF; Low frequency power: hz, HF; High frequency power: hz HF/Total;PNS (parasympathetic nervous system) indicator, LF/HF; SNS (sympathetic nervous system) indicator -168-
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