SAS Enterprise Guideによるデータ解析入門

1 / 83.. SAS Enterprise Guide.... Kengo NAGASHIMA Laboratory of Biostatistics, Department of Parmaceutical Technochemistry, Josai University 2011 11 15

2 / 83 (SAS / SAS Enterprise Guide )

SAS SAS (Statistical Analysis System), 127, 50,000,,,,,... 3 / 83

4 / 83 SAS

5 / 83 SAS...,, ( ), ( ),

6 / 83 SAS Enterprise Guide, Windows SAS, SAS,,,,

7 / 83 SAS SAS Enterprise Guide SAS: SAS Enterprise Guide:, SAS SAS Enterprise Guide...

8 / 83. SAS Enterprise Guide.....

9 / 83 SAS Enterprise Guide PC SAS Enterprise Guide 4.2

10 / 83,,,, : : :

11 / 83 :, :,, :,,

12 / 83 [ ],,

13 / 83 [ ] [ ] [ ]

14 / 83 [ ] ( tamo.xls (Excel ) )

15 / 83 [ ]

16 / 83 : [ ],, [ ]

17 / 83, [ ]

[ SAS ] 18 / 83

19 / 83,, Excel

20 / 83 (.xls) [ ]

21 / 83 Excel, SAS (SAS ) OK

22 / 83.. 2008 4.. 1982 1990 9. 4901,, 1996... :,,.

23 / 83,,,

24 / 83 (1) [ ] [ ] [ ] [ ] [ ] ( & )

25 / 83 (2) [ ], [ ] OK

[ ], [ ] [ ] 464/2549=18.2%, 424/2352=18.0% 26 / 83

27 / 83 [ 1] [ 1 ] ] [ ] [ ] [χ 2 ] [ ] [ ]

28 / 83, (α = 0.05 ) H 0 : H 1 : P-value=0.873, α = 0.05

29 / 83 [ 1] [ 1 ] [ ] [ ] [ ] [2 2 ] [ ] [ ]

30 / 83 =0.0018, 95% 0,

31 / 83,,,

32 / 83 (1) [ ] [ ] [ ] [ ] [ ], [ ] ( & ) [ ]

33 / 83 (2) [ ], [ ] [ ], [ ] [ ]

34 / 83 368/1215=30.3%, 253/760=33.3% 96/1334=7.2%, 171/1592=10.7%

35 / 83 (1) [ ] [ ] [ ] [ ], [ ] [ ] ( & ) [ ] [ ]

36 / 83 (2) [ ] [ ], [ ] [ ] [ ] [ ] [Wald ] [ ]

37 / 83 (1) logit(p ) =β + β x 1 + β x 2,,

38 / 83 (2) 0.25, P-value=0.0017, α = 0.05 0.781, 95% [0.669, 0.912],

39 / 83 1. 464 (18.2%) 2085 2549 424 (18.0%) 1928 2352 888 4013 4901 0.2% [-0.02, 0.02] 2. 368 (30.3%) 847 1215 96 ( 7.2%) 1238 1334 253 (33.3%) 507 760 171 (10.7%) 1421 1592 621 1354 1975 267 2659 2926 3% 3.5% =0.781 [0.669, 0.912]

2..., 1215:1334 ( ), 760:1592 ( ),,,,,..... 40 / 83.

41 / 83 / [ ] [ ] [ ] [ ] [ ]

42 / 83 [ ] [ ] [ ]

43 / 83 2007 10 [4] [5] [ ], 10,, 2, [byouin.xls] 13

44 / 83 (1) [ ] [ ] [ ] [ ]

(2) [ 10 ] [ ], [ ] [ ] & [ ] [ ], [ ], [ ] [ ], 45 / 83

46 / 83 (3) [ ]

47 / 83 10 : 6.3, 1.75 : 10.1, 3.24 10 : 50.4, 8.79 : 45.6, 4.81 10 : 74.9, 12.9 : 81.7, 11.2

48 / 83 10 10, 10,

49 / 83 10 10, 10,

50 / 83 t (1) [ ] [ ] [t ] [2 t ] [ ]

51 / 83 t (2) [ 10, (Log)] [ ], [ ] [ ] & [ ] [ ] [ Q Q ] [ ]

P-value<0.0001,,, 10 (Log) 52 / 83 t ( 10 (Log)) H 0 : H 1 :, 10 (Log), 10 (Log)

53 / 83 t ( 10 ) Q Q,

P-value=0.06,,, 10 54 / 83 t ( 10 ) H 0 : H 1 :, 10, 10

55 / 83 (1) [ ] [ ] [] [ 10 ] [ ], [ ] [ ] & [ ]

56 / 83 (2) [] [Wilcoxon] [ ]

H 0 : H 1 :, 10, 10 P-value=0.04,,, 10 57 / 83

..... 58 / 83 [1] Der G, Everitt BS. Basic statistics using SAS Enterprise Guide : a primer. SAS Publishing, 2007. [2] ( ), SAS Institute Japan ( ). SAS SAS Enterprise Guide., 2008. [3].. 2008 4. [4]. 19 ( ). 2007. http://www.mhlw.go.jp/toukei/list/79-1.html [5]. 19 10 1. 2007. http://www.stat.go.jp/data/jinsui/2007np/index.htm

..... 59 / 83 (, ) :, :, (, ) / :, ( 44), : / : Kaplan-Meier

..... 60 / 83 / (1) [ ] [ ] [], [ ]

..... 61 / 83 / (2) [ ]: [ ]: [Z ]:, []:, [ ]

..... 62 / 83 (1) [ ] [ ] [ ] [2D ]

..... 63 / 83 (2) x, y [ ],, [ ]

..... 64 / 83 (3),, (),,

..... 65 / 83 Kaplan-Meier (1) [ ] [ ] [ ],,

..... 66 / 83 Kaplan-Meier (2) [ ], [ ], [ ] Log-rank Kaplan-Meier

..... 67 / 83, [ ] [ ]

..... 68 / 83 :,

..... 69 / 83

..... [ ] [ ] [ ] [] [RTF] RTF, Word & 70 / 83

..... 71 / 83 [ ] [ ] [RTF] [ ]

..... 72 / 83 ( ) : http://www.josai.ac.jp/~nagasima/contents/ sas/odsstyle/ods_style.html BarrettsBlue Listing Journal

..... 73 / 83 (1) [ ] [] [ ]

..... 74 / 83 (2) [ ] [ ] [OK]

..... 75 / 83 SAS [ ] [ ] [ ] SAS SAS

..... 76 / 83 SAS / SAS Enterprise Guide I.1. SAS (Windows): Windows XP Professional (Service Pack 2 ), Windows Vista Enterprise Edition / Business Edition / Ultimate Edition, Windows XP Professional x64 Edition, Windows Vista Enterprise x64 Edition / Business x64 Edition / Ultimate x64 Edition, Windows 7 Enterprise / Ultimate / Professional / Home Premium Windows XP Home.2. SAS SAS Enterprise Guide SAS Enterprise Guide.3. PC Workgroup PC Workgroup

..... 77 / 83 SAS / SAS Enterprise Guide II.4. (Windows 7): SAS Enterprise Guide SAS Enterprise Guide System.IO.FileNotFoundException Microsoft.Web.Services3, Version=3.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35 1 Web Services Enhancements (WSE) 3.0 for Microsoft.NET http://www.microsoft.com/download/en/details.aspx?id=14089

..... 78 / 83 SAS / SAS Enterprise Guide III.5. http://ftp.sas.com/techsup/download/hotfix/hf2/a20.html http://ftp.sas.com/techsup/download/hotfix/hf2/a32.html http://ftp.sas.com/techsup/download/hotfix/hf2/a53.html

..... 79 / 83 Mantel-Haenszel,, [ 2] [ 2 ] [ ] [ ] [CMH ] [ ] [ ]

..... 80 / 83, Mantel Haenszel (α = 0.05 ) H 0 :, H 1 :, P-value=0.0009, α = 0.05

..... 81 / 83 (1) [ ] [ ] [ ] [WORK] [ ]

..... 82 / 83 (2), [x] [y] [n] [ ],

..... 83 / 83 (3) [ ] [ ] [ ] [x] [y] [n] [ ] 3