-1-
-2 -
2000 1 1 5-3 -
21 10 2-4 -
5-5 -
-6 -
-7-
-8 -
21 2000 21-9-
IT in silico 10-10 -
-11 -
20 21 1993 ICH - 12 -
2007 4 1 NIHThe National Institutes of Health2004 NIH NIH 2006 UK Clinical Research Collaboration UKCRC2004 National Institute of Health ResearchNIHR2005 1-13 -
2006 Office for Strategic Coordination of Health ResearchOSCHRMRCNIHR Translational Medicine Funding Board 21 1996 2000 2 2001 2005 2006 2010 2 2007 20072007 6 19 2025 2007 6 1 2007 4 2007 6 3 2-14 -
10 4 4-15-
2000 M&A 10 20 M&A 1994 1996 1999 2001 2002 5 2007 6 M&A M&A M&A 2007-16 -
2007 M&A M&A - 17 -
7 DDSDrug-Delivery System CRO - 18 -
IT IT MR MR MR CSO MR MR CSO MR - 19 -
2001 9 2003 3 2008 2005 17 18 2005 10 12 2006 6 9 ( ) - 20 -
- 21 -
QOL 2000 21 2003 10 EBMEvidence-based Medicine - 22 -
11-23 -
7.6 (2005 ) 9 10% 2 2006 19901991 30 20 5 5 17% 1 6 2 3 1 75-24 -
10 6 10 16.816-25 -
2005 1,660 7 477 72 387 108 259 429 13 5 35.5 10 49.8% 30 74.9 5 38.4 10 53.7% 30 79.6 14 23.8 18.9 4.9 0.4 12 16 2000 2006 6200 19902000 2000 2005 30 4 7 100 3 7-26 -
1990 2000 16 2001 15 20 20 22 23 25 11 2001 20 17 2001 31 19 2001 30 30 12 43.4 2 14.9% 2 13.0%9.6% 5 7.8% - 27 -
. 20 9 17 15,622 10.006% 500 1 6 1 7 1 10 4,800 2005-28 -
8 2005 1996 2005 10 1,300 2002 6,000 22 SPring-8 15-29 -
2000 19911999 2002 04 1990 1997 10 2000 10 RNAi 2004-30 -
2003 Clinical Research Coordinator - 31 -
- 32 -
- 33 -
- 34 -
18 2015 44 2025 56 2015 2025 2005 1.3 1.7-35 -
OTC - 36 -
- 37 -
2002 2007-38 -
3,349 2005 2,378 70 972 128 2006 64 2007 1 11 M&A 166 128 2006 22-39 -
2006 9 Marketing Specialist - 40 -
- 41 -
18 2005 3 51,000 11,000 13,000 10,000 86,000 2000 2,000 2005 54.1% 2001 18 1999 3 15 2004 7 371-42 -
- 43 -
- 44 -
21 5-45 -
1 2.5-46 -