Protophormia terraenovae
Ž Ž
Gryllus bimaculatus
Neoditrema ransonnetii
Per
Neoditrema ransonnetii
Per 2AH2AH 2AH 2AH
in situ
in vivo dilp6 dilp6
Marsupenaeus japonicus Oryzias latipes
Per PeriodPer Per Per1b Per3
cyp19a2 cyp19a2 cyp19a2
O. latipes éô
C. elegans daf-2 daf-2 Pichia pastoris in vitro
éô
Hasarius adansoni
Cry3 Cry Cry Cry3Cry3 SgCry3 SgCry3Cry3Cry2 Cry2 in situ
Cry3 Cry Cry Cry3Cry3 SgCry3 SgCry3Cry3Cry2 Cry2 in situ
periodtimeless Clock ClockClk ClkClk mrna Clk Clk Rhodnius prolixus
Gryllus bimaculatus Ehab Hassaneen, Yoshiyuki Moriyama, Kenji Tomioka (Okayama Univ., Grad. Nat. Sci. Tech.) Pigment Dispersing Factor (PDF) is a neuromodulator working in various insect circadian systems. In the cricket, G. bimaculatus, injections of pdf dsrna effectively knocked down the pdf mrna levels. The treated crickets maintained the rhythm both under light-dark cycles and constant darkness. However, they showed rhythms with reduced nocturnal activity with prominent peaks at lights-on and -off. The results suggest that PDF is not essential for the rhythm generation but mediates the nocturnality at the downstream of the circadian clock.
Aplysia kurodai in situ
E Nc E Nc E Nc E Nc
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