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- おきみち うすい
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6 HBV HBV (1964) HDV (1977) HCV (1988)
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19 Yotsuyanagi H et al. J Med Virol 2005 Yotsuyanagi H et al. J Hepatol 2002
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21 Universal vaccination (UV) 45 HB 2009
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30 Progress Toward the Elimination of Hepatitis B Virus Transmission Among Health Care Workers in the United States Francis J. Mahoney, et al. Arch Intern Med. 1997;157(22): employees (90%) were eligible to receive hepatitis B vaccine, and 66.5% of them (95% confidence interval, 61.9%- 70.9%) had received 3 doses of hepatitis B vaccine. Studies on long-term protection demonstrate that vaccine induced protection persists at least 11 years even when titers of antibody to hepatitis B surface antigen decline below detectable levels.
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37 HBV HBV HIV 1.7RNA 4.3
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45 HBV+HCV 7.3% ( ) 63% 6.3% HBV 19.6% HCV 66.8% HBV:HBsAg(+) HCV:anti-HCV(+) n=842 K. Koike Univ. of Tokyo
46 HCV 1-6 months 20-30% 70-80% Rare 50% 15-30% 5-7%/ HCC F1: 0-1%/year y F2: 1-2%/year F3: 3-5%/year
47 2/3 NS3 protease inhibitors (Telaprevir, etc.) ) NS5B RNA polymerase inhibitors (R1626, R7128, VCH759, etc.) Ursodeoxycholic acid ( ) Glycyrrhizine ( C (iron depletion therapy)
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49 100 (sus stained virologica al respo onse) IFN Peg-IFN IFN IFN IFN Peg-IFN RBV RBV RBV RBV IFN
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51 15/19 44/64 99/168 p< /8 135/ /262 10/35 12/22 35/67 p< /184 65/242 5/28 Cochran-Armitage test
52 SVR. non-svr) (2009: analysis of 1598 cases from 29 institutes)
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1) Garner J. S.: The Hospital Infection Control Practices Advisory Committee, CDC, Guidelines for Isolation Precautions in Hospitals, 1996. http://wonder.cdc.gov/wonder/prevguid/ p0000419/p0000419.asp.
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Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol
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1988 2000 2002 2004 2006 2008 IFN Lamivudine Adefovir Entecavir 1 Total number 560 Sex (male/female) 424/136 Age (years)* 38 (15-68) Duration of treatment (weeks)* 26 (1-592) Follow-up time (years) 75(05-21
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2015 28 1 89 93 CT C3 Tb PCR XP WBC 7 600/mm 3 CRP 4 08mg/dl MRI MRI CT MRI WBC 9 700/mm 3 CRP 6 09mg/dl CT C3 C2 C7 low density area CT 89 28 1 1a 1b 2 MRI T2 3 CT C3 N95 N95 6ml 90 28 1 4 CT C2 C7 low
Establishment and progress of Sendai virus engineering 2) Schnell, M. J., Mebatsion, T., Conzelmann, K.-K.: EMBO J., 13,4195-4203(1994) 3) Kato, A. et al.: Genes Cells, 1, 569-579 (1996) 4) Nagai,
11.修正_プレゼン資料(鹿児島大学_池田先生)0711
従来の薬剤探索法では 見出すことができなかった 新規抗 HCV 剤グアンファシンの同定 鹿児島大学大学院医歯学総合研究科難治ウイルス病態制御研究センターセンター長池田正徳 従来技術とその問題点 C 型肝炎ウイルス (HCV) に感受性のある唯一動物モデルはチンパンジーのみであるが 霊長類であるチンパンジーを使った研究は現在 倫理的経済的問題からなされていない 現在 すべての抗 HCV 剤は 唯一 HCV
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Fig. 1 Trends of TB incidence rates for all forms and smear-positive pulmonary TB in Kawasaki City and Japan. Incidence=newly notified cases of all fo
Kekkaku Vol. 79, No. 1: 17-24, 2004 17 (Received 21 Aug. 2003/Accepted 18 Nov. 2003) Fig. 1 Trends of TB incidence rates for all forms and smear-positive pulmonary TB in Kawasaki City and Japan. Incidence=newly
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Table 1 Characteristics of the study participants in Imari municipal hospital
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第 14 回肝炎治療戦略会議 215.5.18 ゲノタイプ 2 型に対するソホスブビル + リバビリンによる 12 週間の治療 武蔵野赤十字病院消化器科 泉並木 1 C 型肝炎からの発癌と肝線維化 8 武蔵野赤十字病院 n=1746 Stage 4 Cumulative incidence of HCC (%) 6 4 2 26% 19% 57% 42% 23% n=157 n=425 n=533
女子短大生に対する栄養マネジメント教育とその評価
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