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1 MHC-II II MHC-II MHC- II CD T T TCR T T MHC-II MHC-II T MHC-II MHC-II MHC-II MHC-II Ii Ii-MHC-II MHC-II antigen processing compartment MIIC Regulation of cell surface expression of MHC-II in dendritic cells Kazuyuki Furuta Department of Immunochemistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima-naka, Kita-ku, Okayama, Japan Ii MHC-II MIIC MHC-II CLIP MHC-II MHC-II Ii MIIC CLIP MHC-II CLIP-MHC-II MIIC MHC-II MIIC MHC-II CLIP MHC-II pmhc-ii pmhc-ii MIIC pmhc-ii MHC-II MHC-II MHC-II Toll TLR MHC-II CDCD MHC-II pp.
2 MHC-II MHC-II Ii Ii-MHC-II MIIC Ii CLIP MHC-II CLIP-MHC-II MIIC MIIC MHC-II pmhc-ii MHC-II MHC-II MHC-II MHC-II LPS MHC-II MHC-II KR MHC-II MHC-II MHC-II MHC-II RING-CH E MARCH-I MARCH-I TLR LPS poly I C mrna TLR MARCH-I MHC-II MHC-II MHC-II MHC-II MHC-II MHC-II
3 MHC-II MHC-II T T MHC-II T MHC-II MHC-II HEL TCR A CD T A CD T MHC-II-HEL CD T MHC-II-HEL MHC-II- HEL A T T T T MHC-II T T T MHC-II A HEL A CD T MHC-II-HEL FACS T CFSE CD T T B MHC-II MHC-II FACS MHC-II MHC-II
4 MHC-II T MHC-II TCR MHC-II TCR MHC-II MHC-II TCR MHC-II MHC-II MHC-II MHC-II MHC-II MHC-II MHC-II TCR MHC-II MHC-II MHC-II MHC-II MHC-II E MARCH-I MHC-II MHC-II KR MHC-II MHC-II MHC-II MHC-II T MHC-II T MHC-II T T T T T T T T MHC-II T T T T NIHPaul Roche Trombetta, E.S. Mellman, I.Annu. Rev. Immunol.,,. Berger, A.C. Roche, P.A.J. Cell Sci.,,. Inaba, K., Turley, S., Iyoda, T., Yamaide, F., Shimoyama, S., Reis e Sousa, C., Germain, R., Mellman, I., Steinman, R.M. J. Exp. Med.,,. Pierre, P., Turley, S.J., Gatti, E., Hull, M., Meltzer, J., Mirza, A., Inaba, K., Steinman, R., Mellman, I.Nature,,. Turley, S.J., Inaba, K., Garrett, W.S., Ebersold, M., Unternaehrer, J., Steinman, R.M., Mellman, I.Science,,. Shin, J.S., Ebersold, M., Pypaert, M., Delamarre, L., Hartley, A., Mellman, I.Nature,,. van Niel, G., Wubbolts, R., Ten Broeke, T., Buschow, S.I., Ossendorp, F.A., Melief, C.J., Raposo, G., van Balkom, B.W., Stoorvogel, W.Immunity,,. Hurley, J.H. Stenmark, H.Annu. Rev. Biophys.,,. Matsuki, Y., Ohmura-Hoshino, M., Goto, E., Aoki, M., Mito- Yoshida, M., Uematsu, M., Hasegawa, T., Koseki, H., Ohara, O., Nakayama, M., Toyooka, K., Matsuoka, K., Hotta, H., Yamamoto, A., Ishido, S.EMBO J,.,. DeGassart,A.,Camosseto,V.,Thibodeau,J.,Ceppi,M.,Catalan, N., Pierre, P., Gatti, E.Proc. Natl. Acad. Sci. USA,,. Walseng, E., Furuta, K., Goldszmid, R.S., Weih, K.A., Sher, A., Roche, P.A.J. Biol. Chem.,,. Walseng, E., Furuta, K., Bosch, B., Weih, K.A., Matsuki, Y., Bakke, O., Ishido, S., Roche, P.A. Proc. Natl. Acad. Sci. USA,,. Furuta, K., Ishido, S., Roche, P.A. Proc. Natl. Acad. Sci. USA,,. Sakaguchi, S., Yamaguchi, T., Nomura, T., Ono, M. Cell,,.
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