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6 4) H. Takayama et al.: J. Med. Chem., 45, 1949 (2002). 5) H. Takayama et al.: J. Am. Chem. Soc., 112, 8635 (2000). 6) H. Takayama et al.: Tetrahedron Lett., 42, 2995 (2001). 9) M. Kitajima et al: Chem. Pharm. Bull., 48, 1410 (2000). 10) N. Aimi et al.: Chem. Pharm. Bull., 34, 3064 (1986). 11) M. Kitajima et al.: Natural Medicines, 55, 308 (2001). 12) M. Kitajima et al.: Tetrahedron, 56, 547 (2000). 13) M. Kitajima et al.: Proc. Jpn. Acad., 74, Ser. B, 159 (1998). by G.A. Cordell, Academic Press, San Diego, p. 1, by G.A. Cordell, Academic Press, San Diego, p. 415, 1998.

7 18) M. Kitajima et al.: Phytochemistry, 48, 107 (1998). 19) M. Kitajima et al.: Tetrahedron Lett., 38, 8997 (1997). 20) M. Kitajima et al.: J. Chem. Soc. Perkin Trans. 1, 389 (1998). 21) a) K. Saito et al.: Plant Cell Rep., 20, 267 (2001). b) H. Sudo et al.: Biotechnol. Lett., 24, 359 (2002). b) A.D. Hanson & J.V. Shanks: Metabo. Eng., 4, 1 (2002). c) E.H. Hughes & J.V. Shanks: Metabo. Eng., 4, 41 (2002). d) F. Sato et al.: Proc. Natl. Acad. Sci. USA, 98, 367 (2001). e) K. Springob & K. Saito: Sci. Cult., 68, 76 (2002).

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