carglumic acid
carglumic acid (rinn)
JueI VC, Massey lr,l. Myasthenia gravis. Orphanet J Rare Dis. 2007 Nov 6i2:44. Leonardi M, Raggi A, Antozzi C, Confalonieri P, Maggi L, et al. The relationship between health, disability and quality of life in Myasthenia Gravis: results from an Italian study. J Neurol. 2010 Jani257:98-102. doi 10. 1007/s00415-009-5279-2. Epub 2009 Aug 8. Matsuda M, Dohi-lijima N, Nakamura A, et al. Increase in incidence of elderly onset patients with myasthenia gravis in Nagano Prefecture, Japan. Intern Medicine. 2005 Jun, 44 (a):stz-1. Murai H, Yamashita N, Watanabe M, Nomura Y, et al. Characteristics of nyasthenia gravis according to onset-age: Japanese nationwide survey. J Neurol Sci. 20tl Jun 15; 305(l-2) i97-102. doi: 10. 1016/j. jns.20lt.03.004.epub2ol1 Nlar 26. Okinaka S, Reese HH, Katsuki S, et al. The prevalence of multiple sclerosis and other neurological diseases in Japan. 1966,47 (Suppl l9):68-76. Romi F, Gilhus NE, AarIi Jn. Myasthenia gravis: clinical, immunological, and therapeutic advances. Acta Neurol Scand. 2005 Feb; 111(2):134-4I.
AUCo-e (ng'tu,/nn-)
I lq!e+ti
87
):, I -, *rjrjn-,
6 2tL7 7
9.7 a?/1r ) 38. 9 r1qlonl
t24 'oe 1- I
Co (nc/ml)
s(+)l+ifvu (mllmrn) X (nglml)
tttto 7) sc/i,!$fij (300rgl E tfl) *5$offiH*o
copies/ml- =too,ooo Sloo,ooo copies/ml-
$mso 54 6mg 75 6mg D--? > = l--/v 36.0mg 2 Omg 27mg Q connoo"orr
028 mg'/ml 7Omg 0.28 mg,/ml 0.20 0.47 ntg,/ ml ng,/ml 50mg /:4 7 tv 047 mg,/ml l4{ 0.14 0.34 mg,/ml mg'/ml 014 0.34 mg'/ml mg,/ml Q comomtrt
177ev >y 4C7Y> 7 -= l-y' 7+tt / t t> )l tv ts-v P e> Q Comornurt
C Codrd.tr{.1
0 { 3 r? 16 10 3r 3 { 5 6 I 3 9lr1rr, 0 a 12 $ an 31 *+t9i:1+t) &+B i=ir a+gsi_t r+ui I l3e_xlzbrrf,9fofit+utel s4iqrri 6e t 1pj (hr) 71.09 {64.46,78 4l) t06.61 (94.73, r l9 98) t 4 l.l9 (132 64, I 50 30) (7.97, t0.0t) t4.m ( r3.4q l5 45) t7.21 (15 46-19.15) l.l + (094, 1.38) 1.53 (1.21,194) 22E u.90-273) 0.62,1.76) t.l6 (1.13, I l9) 190 0 80,200) z,t I u 99, 2.38) t64 0 49, r 8l) 2.12 (2.46,3 0t) G csftd.nffit
AUCuz+r fue'tr,/rl\ C tn. (!s,,/ rj.\ c2451 (rs./ml \ AUCou +n, (ub'tu/nj,\ Crr fus'/nl]. c2g1 (ro./mr \ ll lr (8.8.13.9) 2.4r fl.8.3.4) 142 60 (L16.68. t74.29\ l8.39ll /L5.13.22.35',1 1.90! i 42.2 54\ 202.43 t45.99 (l59.74.2s6.53\ (L3t.t4. 162.52\ 25.96s 17.17r (20.20.33.36\ fi5.80. I8.661 3.62\ 2.41! (2.38. 5.50) (2.13-2.72\ 14826 (93.86.234.18) I 5.88! (L0.2s.24.60\ 3.01{ fl.87. 4.85) Q Cortactrat
Q cornootrr
Q Cornornu*
r: i? y 2 zl tv 0.75%
vt.y ) 7, )v0.75% 7 tv=-)v
*77aiE:fiil 5pg azyv>y *7Aaid:fril 20rrg arrury *A7oEHil 60ug 72rU>Y
I 5ue
t Elffi tt+tvz ito.lb ' il#tr, r\t tv2 No.2o t Elffi r\l.tvz No.2z o ilffi, tt+.tvz t{0.24
t'l ET tv=*tv N.N'-t 7 - =)V,t:, 7 - = V l,/ )7 :. >
x7:a- 1., ztrty]/z- /\1.,7- -79*yV=
-49,999,,\