130105ｨ 0902ｨｪ 080201ｨ ｨｺｨｰ0608 010602. 01-08 04ｨｮｨｬ07ｨｪｨ 06ｨｲ08ｨｪ060909ｨｺｨ -08ｨｲ01080209ｨ 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 050600ｨｨ07 040201ｨ ｨｺ02ｨｨ06ｨｪ02ｨｪ 09ｨｲ0902ｨｰ: 07080600. 01-08 0005ｨ 0102ｨｪ 0108ｨｨ0006080609 II 00090809, 050600ｨｨ07 07080600. 01-08 06ｨｨ0106ｨｬｨｨ08 02ｨ 09ｨｺｨ 050609 010809, 050600ｨｨ07 010602. 01-08 000208ｨ 05ｨｨ08ｨ ｨｺ0609ｨ 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ, 00ｨ 08ｨｪｨ 07080600. 01-08 050902ｨｰ05ｨ 060608ｨ 0609ｨ 010609, 050600ｨｨ07 010602. 01-08 00ｨ 0800ｨ 08ｨｨｨｰｨ 0006ｨｪ04ｨ 080609ｨ 010809, 050600ｨｨ07 040201ｨ ｨｺ02ｨｨ06ｨｪｨｪｨ ｨｺ06050200ｨｨ07 010602. 01-08 01ｨｨｨｪｨ 0106 ﾂ0209ｨ 010809-050600ｨｨ07 010602. 01-08 0206ｨ 0806ｨｬｨｨ08 0106 ﾂ0209 000008-050600ｨｨ07 010602. 01-08 080902ｨｪ 01ｨｮ010209 00090809 ｰ00ｨ 08ｨｨ02ｨ 0706ｨ ｨｪｨｪｨ ｱ - 050600ｨｨ07 010602. 01-08 05ｨｰ0200ｨ ｨｪ 0202ｨｪ ﾂ0209 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 050600ｨｨ07 010602. 01-08 0705ｨｨ07 02030608000609ｨ -00ｨ ｨｺ020106ｨｪ09ｨｺｨ 0709 ｰ050902ｨｰｨ 03ｨｺｨ ｨｰ0208ｨｨｨｪｨ ｱ - 050600ｨｨ07 07080600. 01-08 08ｨｰｨ ｨｪｨ 09 0203ｨｮ0801030209 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 0305060901ｨｨ09 010602. 01-08 0602ｨｬ02ｨｪｨｮ00ｨ 0206ｨｪ0609ｨ 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 050600ｨｨ07 010602. 01-08 050108ｨ 09ｨｺｨ 08ｨ ｨｬ02ｨｪ0609ｨ 00090809-05ｨｰｨ 08ｨ 05ｨ 000608ｨ 010602. 01-08 02ｨｨｨｬｨｨｨｰｨｲ08 08ｨ 08ｨ 09ｨｰｨ ｨｰ0209 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ ｨC 00ｨ 08ｨｪｨ 07080600. 01-08 0908ｨｨ09ｨｰ06 080603ｨｮ01ｨ 080609 00090809 ｰ00ｨ 08ｨｨ02ｨ 0706ｨ ｨｪｨｪｨ ｱ - 050600ｨｨ07 010602. 01-08 000902ｨｰｨ ｨｪｨ 08ｨｲｨｰ0609ｨ 010809-050600ｨｨ07 07080600. 01-08 0102ｨｪ ﾂ06 01ｨ ﾂ0209 0709 ｰ050902ｨｰｨ 03ｨｺｨ ｨｰ0208ｨｨｨｪｨ ｱ - 050600ｨｨ07 010602. 01-08 08020107 01ｨｨｨｺ06050609 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 0305060901ｨｨ09 010602. 01-08 0609ｨ 03ｨ 09ｨｺｨ 050209ｨ 010809-050600ｨｨ07 010602. 01-08 04ｨ 01ｨｺ06 0302050609 00090809 ｰ00ｨ 08ｨｨ02ｨ 0706ｨ ｨｪｨｪｨ ｱ - 050600ｨｨ07 07080600. 01-08 01ｨｨｨｺ0605ｨ ｨｦ 0302ｨｪｨｺ0609 00090809 ｰ050902ｨｰｨ 00ｨ 08ｨｨｨｪｨ ｱ - 00ｨ 08ｨｪｨ 010602. 01-08 0609ｨ ｨｪ 030208 ﾂ0209 V 00090809-050600ｨｨ07 010602. 01-08 02ｨｨｨｬｨｨｨｰｨｲ08 04ｨ 0209 000004 ｨ 0605ｨｪｨｨ02ｨ 010602. 01-08 0806ｨｪ09ｨｰｨ ｨｪｨｰｨｨｨｪ 04ｨ ｨｬ030209 000008-050600ｨｨ07 010602. 01-08 0906ｨ ｨ 06020804ｨｨ0209ｨ 000201ｨｨ02ｨｨｨｪ09ｨｺｨｨ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ - 050600ｨｨ07 010602. 01-08 090603ｨｨ01ｨ 08 08ｨｨｨｪｨｺ0609 00090809 ｰ050902ｨｰｨ 08ｨｪｨｪｨ ｱ - 050600ｨｨ07 0801080209 04ｨ ｨｺ060802090706ｨｪ0102ｨｪ02ｨｨ07 ｨｨ ｨｺ0607ｨｨ07: 010602. 01-08 04ｨｮｨｬ07ｨｪｨ 06ｨｲ08ｨｪ060909ｨｺｨ -08ｨｲ01080209ｨ 0805ｨｨｨｪｨｨｨｺｨ 0706 ｨｺｨ 0801ｨｨ06050600ｨｨ07, 080009, M07 1431 050600ｨｨ07, 0102060800ｨｨ 050600ｨｨｨｦ09ｨｺｨｨ 1 e-mail: bgcardiology@mail.bg GSM - 0897 926374, ｨｰ0205.: (02) 9320 725 03ｨｺ09070208ｨｰ02ｨｪ ｨｺ06ｨｪ0902ｨｪ09ｨｮ09 04ｨ 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ-ｨｺ06ｨｪ090208ｨｰｨｨ08ｨ ｨｴｨｨ07 02ｨｪ04ｨｨｨｬ 0708ｨｨ 09ｨｲ080102 ﾂｨｪ06-09ｨｲ010609ｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07 04ｨ ｨ 06ｨｰｨｪｨ 0008ｨｮ07ｨ 04ｨ 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 ｨｪｨ 030908060702ｨｦ09ｨｺ06ｨｰ06 0108ｨｮ030209ｨｰ0906 0706 ｨｺｨ 0801ｨｨ06050600ｨｨ07 Expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease The Task Force on ACE-inhibitors of the European Society of Cardiology 09ｨｲ0500ｨ 0809ｨｺｨ ｨｺｨ 0801ｨｨ06050600ｨｨ07 ｨ 08. 2/2006 000601ｨｨｨｪｨ XII ISSN 1310-7488 0200ｨｨ02ｨｨｨ 0502ｨｪ 060800ｨ ｨｪ ｨｪｨ 0208ｨｮ030209ｨｰ0906ｨｰ06 ｨｪｨ ｨｺｨ 0801ｨｨ06050604ｨｨｨｰ02 09 09ｨｲ0500ｨ 08ｨｨ07 0009ｨｨ ﾂｨｺｨｨ 0708ｨ 09ｨ 04ｨ 07ｨ 0402ｨｪｨｨ 030802090601: 01-08 0908ｨｨ09ｨｰ06 0306070609 030802010702 ﾂｨ ｨｰｨｪｨ 0706010006ｨｰ0609ｨｺｨ ｨｨ 0702 ﾂｨ ｨｰ: 24 ｨｺｨ 08ｨ ｨｰｨ 020202 0108ｨ 00ｨｨ ﾂ02ｨｪ 01ｨｨ04ｨ ｨｦｨｪ 01-08 020207ｨｪ 05ｨ 00060809ｨｺｨｨ European Heart Journal (2004) 25, 1454-1470 0507ｨｨ09ｨ ｨｪｨｨ02ｨｰ06 0902 06ｨ 08ｨ ｨ 06ｨｰ09ｨ 09 090309010804050806 00060608060301 0708080508060309 www.bgcardiology.com 1
13European Heart Journal (2004) 25, 1454-1470 Expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease The Task Force on ACE-inhibitors of the European Society of Cardiology Task Force Members, Josｨｦ Lｨｮpez-Sendｨｮn, Chairperson* (Spain), Karl Swedberg (Sweden), John McMurray (UK), Juan Tamargo (Spain), Aldo P. Maggioni (Italy), Henry Dargie (UK), Michal Tendera (Poland), Finn Waagstein (Sweden), Jan Kjekshus (Norway), Philippe Lechat (France), Christian Torp-Pedersen (Denmark) ESC Committee for Practice Guidelines (CPG), Silvia G. Priori (Chairperson) (Italy), Maria Angeles Alonso Garcia (Spain), Jean-Jacques Blanc (France), Andrzej Budaj (Poland), Martin Cowie (UK), Veronica Dean (France), Jaap Deckers (The Netherlands), Enrique Fernandez Burgos (Spain), John Lekakis (Greece), Bertil Lindahl (Sweeden), Gianfranco Mazzotta (Italy), Keith McGregor (France), Jo00o Morais (Portugal), Ali Oto (Turkey), Otto A. Smiseth (Norway) Document Reviewers, Maria Angeles Alonso Garcia (CPG Review Coordinator) (Spain), Diego Ardissino (Italy), Cristina Avendano (Spain), Carina Blomstr02m-Lundqvist (Sweden), Denis Clｨｦment (Belgium), Helmut Drexler (Germany), Roberto Ferrari (Italy), Keith A. Fox (UK), Desmond Julian (UK), Peter Kearney (Ireland), Werner Klein (Austria), Lars K02ber (Denmark), Giuseppe Mancia (Italy), Markku Nieminen (Finland), Witold Ruzyllo (Poland), Maarten Simoons (The Netherlands) Kristian Thygesen (Denmark), Gianni Tognoni (Italy), Isabella Tritto (Italy), Lars Wallentin (Sweden) 05ｨｲ01ｨｲ0803ｨ ｨｪｨｨ02 03080201ｨｨ09050609ｨｨ02 0805ｨ 09060902 070802070608ｨｲｨｺｨｨ 01ｨｨ09ｨ ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ ｨｰｨ 07090601 08ｨ 08ｨｬｨ ｨｺ06050600ｨｨ07 0207080201020502ｨｪｨｨ02 0805ｨ 09ｨｨ00ｨｨｨｺｨ 02ｨｨ07 ｨｪｨ 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 08ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨ ﾂ02ｨｪ 07080600ｨｨ05 000201ｨ ｨｪｨｨ04ｨｲｨｬ ｨｪｨ 0102ｨｦ09ｨｰ09ｨｨ02 030002ｨｺｨｰｨｨ ｨｪｨ 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 0902ｨｬ0601ｨｨｨｪｨ ｨｬｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 0102090806010608ｨｬ06ｨｪｨ 05ｨｪｨｨ 020002ｨｺｨｰｨｨ 08ｨｪｨｰｨｨ07080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪｨｨ 020002ｨｺｨｰｨｨ 09ｨｲｨ 0802 ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 030002ｨｺｨｰｨｨ 09ｨｲ0801ｨｮ 00ｨｨｨ 08ｨｨｨｪ0605ｨｨｨｰｨｨ ﾂｨｪｨｨ07 ｨ ｨ 05ｨ ｨｪ09 05ｨｰ08ｨ ｨｪｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 030806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ07 0902ｨｺｨ 0809ｨｰ0902ｨｪｨｨ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 020604ｨｨ08ｨ ｨｪ02 0805ｨｨｨｪｨｨ ﾂｨｪｨ 0200ｨｨｨｺｨ 09ｨｪ0609ｨｰ ｨｨ 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨ ｨｮ0706ｨｰ0802ｨ ｨ 05ｨｲ080102 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ 0308ｨｨ020205ｨｪｨ 010604ｨ 0508ｨ 09ｨｪ02ｨｪｨｨ02 ｨｬ020301ｨｮ 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 ｨｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ-0802020207ｨｰ0608ｨｪｨｨｨｰ02 ｨ 0506ｨｺ0208ｨｨ 0809ｨｨｨｬ07ｨｰ06ｨｬｨ ｨｰｨｨ ﾂｨｪｨ 05020906ｨｺｨ ｨｬ0208ｨｪｨ 09ｨｨ09ｨｰ0605ｨｪｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07 02ｨｨｨ 09ｨｰ0605ｨｪｨ 09ｨｲ080102 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ 0209ｨｰｨｲ08 ｨｬｨｨ06ｨｺｨ 080102ｨｪ ｨｨｨｪ00ｨ 08ｨｺｨｰ 0808ｨｰ0208ｨｨｨ 05ｨｪｨ 01ｨｨ070208ｨｰ06ｨｪｨｨ07 00ｨｰ0608ｨｨ ﾂｨｪｨ 07080600ｨｨ05ｨ ｨｺｨｰｨｨｨｺｨ 0708ｨｨ 09ｨｨ0906ｨｺ 08ｨｨ09ｨｺ 06ｨｰ 09ｨｲ080102 ﾂｨｪ06-09ｨｲ01060906 04ｨ ｨ 06050709ｨ ｨｪ02 03080600ｨｨ05ｨ ｨｺｨｰｨｨｨｺｨ ｨｪｨ 09ｨｪ0204ｨ 07ｨｪｨ 09ｨｲ080102 ﾂｨｪｨ 09ｨｬｨｲ08ｨｰ 09ｨｨｨ 05ｨｨ060008ｨ 00ｨｨ07 2
1303080201ｨｨ09050609ｨｨ02 04ｨｲｨｺ0609060109ｨｰ09ｨ ｨｰｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨｨｰ02 ｨｺ06ｨｪ0902ｨｪ09ｨｮ09ｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ ｨｨｨｬｨ ｨｰ 04ｨ 020205 01ｨ 0708020109ｨｰa0907ｨｰ 0909ｨｨ ﾂｨｺｨｨ 04ｨｪｨ ﾂｨｨｨｬｨｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ 0706 01ｨ 0102ｨｪｨ ｨｰ02ｨｬｨ, 04ｨ 01ｨ 0706ｨｬｨ 00ｨ ｨｰ ｨｪｨ 0502ｨｺｨ 08ｨｨｨｰ02 0708ｨｨ 0708020202ｨｪｨｺｨ ｨｪｨ 07060504ｨｨｨｰ02 ｨｨ 08ｨｨ09ｨｺ060902ｨｰ02 06ｨｰ 0607080201020502ｨｪｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ ﾂｨｪｨ ｨｨ05ｨｨ ｨｰ0208ｨ 070209ｨｰｨｨ ﾂｨｪｨ 070806020201ｨｮ08ｨ. 0602 ｨｰ0807ｨ 09ｨ 01ｨ ｨ ｨｲ01ｨ ｨｰ 0706050204ｨｪｨｨ 0708ｨｨ 090402ｨｬｨ ｨｪ02 ｨｪｨ 08020302ｨｪｨｨ07 09 02030201ｨｪ0209ｨｪｨ ｨｰｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨ 0708ｨ ｨｺｨｰｨｨｨｺｨ. 03080204 070609050201ｨｪｨｨｨｰ02 000601ｨｨｨｪｨｨ ｨ 0701ｨ ｨｨ0401ｨ 0102ｨｪｨｨ 00060507ｨｬ ｨ 0806ｨｦ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ 06ｨｰ 030908060702ｨｦ09ｨｺ06ｨｰ06 0108ｨｮ030209ｨｰ0906 0706 ｨｺｨ 0801ｨｨ06050600ｨｨ07 (030208, 03SC) ｨｨ 08ｨ 0405ｨｨ ﾂｨｪｨｨ 0108ｨｮ00ｨｨ 060800ｨ ｨｪｨｨ04ｨ 02ｨｨｨｨ ｨｨ 09080601ｨｪｨｨ 0108ｨｮ030209ｨｰ09ｨ. 060609ｨ ｨｨ0406ｨ ｨｨ05ｨｨ02 06ｨｰ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｬ060302 01ｨ ｨｨ04050603ｨｨ ｨｪｨ 08ｨｨ09ｨｺ ｨｰ0201ｨｪｨｨ07 ｨ 09ｨｰ0608ｨｨｨｰ02ｨｰ ｨｨ 09ｨ 05ｨｨ01ｨｪ0609ｨｰ, ｨ ｨｺ06 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨｨｰ02 ｨｪ02 09ｨ ｨｨ040006ｨｰ0902ｨｪｨｨ ﾂ080204 ｨｪ020609070608ｨｨｨｬ 070806020209 ｨｪｨ 090402ｨｬｨ ｨｪ02 ｨｪｨ 08020302ｨｪｨｨ07. 060609ｨ 02 0201ｨｪｨ 06ｨｰ 0708ｨｨ ﾂｨｨｨｪｨｨｨｰ02, 070608ｨ 01ｨｨ ｨｺ06ｨｨｨｰ06 030208 ｨｨ 0108ｨｮ00ｨｨ 09ｨ 07ｨｮｨ 05ｨｨｨｺｨｮ09ｨ 05ｨｨ 070802070608ｨｲｨｺｨｨ 04ｨ 000608ｨｬｨｮ05ｨｨ08ｨ ｨｪ02 ｨｨ ｨｨ0401ｨ 09ｨ ｨｪ02 ｨｪｨ 070802070608ｨｲｨｺｨｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮ09ｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ. 00ｨｲ070802ｨｺｨｨ 00ｨ ｨｺｨｰｨ, ﾂ02 09ｨｰｨ ｨｪ01ｨ 08ｨｰｨｨｨｰ02 04ｨ ｨｨ0401ｨ 09ｨ ｨｪ02 ｨｪｨ ｨｺｨ ﾂ0209ｨｰ0902ｨｪｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨ ｨｺ06ｨｪ090209ｨｪ09ｨｮ09ｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ 09ｨ 0106ｨ 0802 010200ｨｨｨｪｨｨ08ｨ ｨｪｨｨ, 070609050201ｨｪｨｨｨｰ02 07080200050201ｨｨ ｨｪｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｰｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨｨｰ02 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ, 07ｨｮｨ 05ｨｨｨｺｨｮ09ｨｪｨｨ 09 0802000208ｨｨ08ｨ ｨｪｨｨ 0907ｨｨ09ｨ ｨｪｨｨ07 ｨｬ020301ｨｮ 1985 ｨｨ 1998 00. 0706ｨｺｨ 04ｨ 01ｨ, ﾂ02 09 07080206ｨ 05ｨ 01ｨ 09ｨ ｨｴｨ ｨｰｨ ﾂｨ 09ｨｰ 06ｨｰ 0905ｨｮ ﾂｨ ｨｨｨｰ02 ｨｪ02 09ｨ 0907ｨ 0402ｨｪｨｨ ｨｬ02ｨｰ060106050600ｨｨ ﾂｨｪｨｨｨｰ02 09ｨｰｨ ｨｪ01ｨ 08ｨｰｨｨ. 05ｨ ｨｰ0609ｨ 02 ｨｨ04ｨｺ0506 ﾂｨｨｨｰ0205ｨｪ06 09ｨ 03ｨｪ06 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｰｨ ｨｨ 070802070608ｨｲｨｺｨｨｨｰ02 01ｨ ｨ ｨｲ01ｨ ｨｰ 0708020109ｨｰｨ 0902ｨｪｨｨ 09 05020902ｨｪ 04ｨ ｨｨｨｪｨｰ0208070802ｨｰｨ 02ｨｨ07 000608ｨｬｨ ｨｰ. 0007060905020109ｨｰ09ｨｨ02, 0708060008ｨ ｨｬｨｨｨｰ02 04ｨ ｨｰ0701ｨｪ06ｨｰ06 ｨｨ0407ｨｲ05ｨｪ02ｨｪｨｨ02 ｨｰ0807ｨ 09ｨ 09ｨｲｨｴ06 01ｨ ｨ ｨｲ01ｨ ｨｰ 0106ｨ 0802 07080609020102ｨｪｨｨ. 0806ｨｬｨｨｨｰ02ｨｰｨｲｨｰ 04ｨ 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ (080304) ｨｪｨ 0302K ｨｺ06ｨｪｨｰ080605ｨｨ08ｨ ｨｨ ｨｺ06060801ｨｨｨｪｨｨ08ｨ ｨｨ040006ｨｰ0907ｨｪ02ｨｰ06 ｨｪｨ ｨｪ0609ｨｨ 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｨ 02ｨｺ09070208ｨｰｨｪｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮ09ｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ 06ｨｰ 09ｨｲ06ｨｰ0902ｨｰｨｪｨｨｨｰ02 0202050209ｨｨ, 02ｨｺ09070208ｨｰｨｪｨｨ ｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮ09ｨｪｨｨ 0008ｨｮ07ｨｨ. 02ｨｰ 02ｨｺ09070208ｨｰｨｨｨｰ02, ｨｨ04ｨ 08ｨ ｨｪｨｨ 09 ｨｰ0204ｨｨ 07ｨｨ0302ｨｴｨｨ 02ｨｺｨｨ07ｨｨ, 0902 ｨｨ04ｨｨ09ｨｺ09ｨ 01ｨ 0708020109ｨｰｨ 0907ｨｰ 0600ｨｨ02ｨｨｨ 05ｨｪｨｨ ｨｨ0407090502ｨｪｨｨ07, 08ｨ 04ｨｺ08ｨｨ09ｨ ｨｴｨｨ 0909ｨｨ ﾂｨｺｨｨｨｰ02 ｨｨｨｬ 0904ｨ ｨｨｨｬ0606ｨｰｨｪ060302ｨｪｨｨ07, ｨｺ06ｨｨｨｰ06 ｨ ｨｨ01ｨ ｨｬ060005ｨｨ 01ｨ 0902 09ｨｲ040708ｨｨ02ｨｬｨ ｨｰ ｨｺｨ ｨｰ06 0102ｨｦ09ｨｰ09ｨｨｨｰ0205ｨｪｨｨ ｨｨ05ｨｨ 0706ｨｰ02ｨｪ02ｨｨｨ 05ｨｪｨｨ ｨｺ06ｨｪ0005ｨｨｨｺｨｰｨｨ ｨｪｨ ｨｨｨｪｨｰ02080209ｨｨ. 060204ｨｨ 0600ｨｨ02ｨｨｨ 05ｨｪｨｨ 000608ｨｬｨｮ050708ｨｨ 0902 09ｨｲ0108ｨ ｨｪ0709ｨ ｨｰ 09 ｨ 0801ｨｨ09ｨ ｨｪｨ European Heart House, 0202ｨｪｨｰ08ｨ 05ｨ ｨｰｨ ｨｪｨ 030208. 0806ｨｬｨｨｨｰ02ｨｰｨｲｨｰ 09ｨｲｨｴ06 ｨｰｨ ｨｺｨ 06ｨｰ000609ｨ 0807 04ｨ 060106ｨ 080709ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨｰ0204ｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ, 02ｨｺ09070208ｨｰｨｪｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮ09ｨｪｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰｨｨ ｨｨ ｨｨ0407090502ｨｪｨｨ07. 0002050209ｨ ｨｰｨ 0008ｨｮ07ｨ ｨｺ05ｨ 09ｨｨ00ｨｨ02ｨｨ08ｨ 07060504ｨ ｨｰｨ ｨｨ 0200ｨｨｨｺｨ 09ｨｪ0609ｨｰｨｰｨ 06ｨｰ 070802070608ｨｲ ﾂ09ｨ ｨｪｨｨｨｰ02 070806020201ｨｮ08ｨｨ ｨｨ/ｨｨ05ｨｨ 0502- ﾂ02ｨｪｨｨ07 ｨｨ ｨｺｨ ｨｰ02000608ｨｨ04ｨｨ08ｨ 0106ｨｺｨ 04ｨ ｨｰ0509ｨｰ09ｨ ｨｰｨ ｨｺｨ ｨｺｨｰ06 02 07060906 ﾂ02ｨｪ06 09 0905020109ｨ ｨｴｨｨｨｰ02 ｨｰｨ ｨ 05ｨｨ02ｨｨ: 0805ｨ 09 ｨｪｨ 070802070608ｨｲｨｺｨｨｨｰ02 0805ｨ 09 I 0206ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ ｨｨ/ｨｨ05ｨｨ 06ｨ ｨｴ06 09ｨｲ0005ｨ 09ｨｨ02, ﾂ02 01ｨ 0102ｨｪｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ ﾂｨｪｨ 070806020201ｨｮ08ｨ ｨｨ05ｨｨ 0502 ﾂ02ｨｪｨｨ02 09ｨ 0706050204ｨｪｨｨ ｨｨ 0200ｨｨｨｺｨ 09ｨｪｨｨ 0805ｨ 09 II 0805ｨ 09 IIｨ 0805ｨ 09 IIb 07090601 030806ｨｰｨｨ09060802 ﾂｨｨ09ｨｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ ｨｨ/ｨｨ05ｨｨ 08ｨ 04ｨｬｨｨｨｪｨ 09ｨ ｨｪ02 ｨｪｨ ｨｬｨｪ02ｨｪｨｨ07ｨｰｨ 04ｨ 07060504ｨ ｨｰｨ / 0200ｨｨｨｺｨ 09ｨｪ0609ｨｰｨｰｨ 06ｨｰ 01ｨ 0102ｨｪｨ 070806020201ｨｮ08ｨ / 0502 ﾂ02ｨｪｨｨ02 03080206ｨ 05ｨ 01ｨ 09ｨ ｨｰ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ /ｨｬｨｪ02ｨｪｨｨ07 04ｨ 07060504ｨ /0200ｨｨｨｺｨ 09ｨｪ0609ｨｰ 03060504ｨ ｨｰｨ /0200ｨｨｨｺｨ 09ｨｪ0609ｨｰｨｰｨ 09ｨ 0706-0905ｨ ｨ 06 070601ｨｺ08020702ｨｪｨｨ 06ｨｰ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ /ｨｬｨｪ02ｨｪｨｨ07 0805ｨ 09 III* 0206ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ ｨｨ/ｨｨ05ｨｨ 06ｨ ｨｴ06 09ｨｲ0005ｨ 09ｨｨ02, ﾂ02 0502 ﾂ02ｨｪｨｨ02ｨｰ06 ｨｪ02 02 0706050204ｨｪ06, ｨ 09 ｨｪ07ｨｺ06ｨｨ 0905ｨｮ ﾂｨ ｨｨ ｨｬ060302 01ｨ ｨ ｨｲ0102 ｨｨ 09080201ｨｪ06 *070706ｨｰ0802ｨ ｨ ｨｰｨ ｨｪｨ ｨｺ05ｨ 09 III ｨｪ02 02 060106ｨ 0802ｨｪ06 06ｨｰ 030208 01ｨｨ09ｨ ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ 01ｨｨ0906 ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ 08 02ｨ ｨｪｨｪｨｨ, 070605ｨｮ ﾂ02ｨｪｨｨ 06ｨｰ ｨｬｨｪ060006ｨ 0806ｨｦｨｪｨｨ 08ｨ ｨｪ0106ｨｬｨｨ04ｨｨ08ｨ ｨｪｨｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07 ｨｨ05ｨｨ ｨｬ02ｨｰｨ ｨ ｨｪｨ 05ｨｨ04ｨｨ. 01ｨｨ0906 ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ B 02ｨ ｨｪｨｪｨｨ, 070605ｨｮ ﾂ02ｨｪｨｨ 06ｨｰ 0201ｨｪ06 08ｨ ｨｪ0106ｨｬｨｨ04ｨｨ08ｨ ｨｪ06 ｨｺ05ｨｨｨｪｨｨ ﾂｨｪ06 070806ｨｮ ﾂ09ｨ ｨｪ02 ｨｨ05ｨｨ 06ｨｰ ｨｪ0208ｨ ｨｪ0106ｨｬｨｨ04ｨｨ08ｨ ｨｪｨｨ 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07 01ｨｨ0906 ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ C 0806ｨｪ0902ｨｪ09ｨｮ09ｨｪ06 ｨｬｨｪ02ｨｪｨｨ02 ｨｪｨ 02ｨｺ09070208ｨｰｨｨｨｰ02 ｨｨ/ｨｨ05ｨｨ ｨｬｨ 05ｨｺｨｨ 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07 0402ｨｪｨｨｨｪ-ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ0609ｨ ｨｰｨ 09ｨｨ09ｨｰ02ｨｬｨ (040805) ｨｨ0008ｨ 02 09ｨ 03ｨｪｨ 08060507 09 09ｨｲ080102 ﾂｨｪ06-09ｨｲ010609ｨ ｨｰｨ 07ｨ ｨｰ06050600ｨｨ07. 03080204 070609050201ｨｪ06ｨｰ06 01020902ｨｰｨｨ0502ｨｰｨｨ02 ｨ 020302 ｨｨ0409ｨｲ080302ｨｪｨ 06ｨ 03ｨｨ08ｨｪｨ ｨｨ04090502010609ｨ ｨｰ020509ｨｺｨ 0102ｨｦｨｪ0609ｨｰ 04ｨ ｨｮ09ｨｰｨ ｨｪ06090709ｨ ｨｪ02 ｨｪｨ 09ｨｲ04ｨｬ0603ｨｪｨｨｨｰ02 ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 07060504ｨｨ 06ｨｰ 0708ｨｨ05060302ｨｪｨｨ02ｨｰ06 ｨｪｨ ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 ｨｪｨ ｨ ｨｪ00ｨｨｨｰ02ｨｪ04ｨｨｨｪ-ｨｺ06ｨｪ090208ｨｰｨｨ08ｨ ｨｴｨｨ07 02ｨｪ04ｨｨｨｬ (080503-I) 0708ｨｨ 08ｨ 0405ｨｨ ﾂｨｪｨｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 09ｨｲ09ｨｰ0607ｨｪｨｨ07. 00 080204ｨｮ05ｨｰｨ ｨｰ ｨｪｨ ｨｰ0609ｨ ｨｰ0204ｨｨ ｨｬ0201ｨｨｨｺｨ ｨｬ02ｨｪｨｰｨｨ ｨ 0701ｨ 070802070608ｨｲ ﾂｨ ｨｪｨｨ 04ｨ 0502 ﾂ02ｨｪｨｨ02 ｨｪｨ 09ｨｲ080102 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ (0501), ｨ 08ｨｰ0208ｨｨｨ 05ｨｪｨ 01ｨｨ070208ｨｰ06ｨｪｨｨ07 (0809), 0609ｨｰｨｲ08 ｨｨ 010806ｨｪｨｨ ﾂ02ｨｪ ｨｬｨｨ06ｨｺｨ 080102ｨｪ ｨｨｨｪ00ｨ 08ｨｺｨｰ. 000205ｨｰｨ ｨｪｨ ｨｰ0604ｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰ 02 01ｨ ｨｪｨ 0708ｨ 09ｨｨ 07080200050201 ｨｪｨ 0609ｨｪ0609ｨ ｨｪｨｨ07ｨｰｨ ｨｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨｨｰ02 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ 04ｨ 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ 080503-I 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09ｨｲ09 09ｨｲ080102 ﾂｨｪ06-09ｨｲ010609ｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07. ﾁ0502ｨｪ060902ｨｰ02 ｨｪｨ 08ｨ ｨ 06ｨｰｨｪｨ ｨｰｨ 0008ｨｮ07ｨ 04ｨ 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ ｨｺ06ｨｪ090208ｨｰｨｨ08ｨ ｨｴｨｨ07 02ｨｪ04ｨｨｨｬ 0708ｨｨ 09ｨｲ080102 ﾂｨｪ06-09ｨｲ010609ｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07 ｨ 0701ｨ ｨｪ06ｨｬｨｨｨｪｨｨ08ｨ ｨｪｨｨ 06ｨｰ 0806ｨｬｨｨｨｰ02ｨｰｨ 04ｨ 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｪｨ 030908060702ｨｦ09ｨｺ06ｨｰ06 0108ｨｮ030209ｨｰ0906 0706 ｨｺｨ 0801ｨｨ06050600ｨｨ07 3
13(030208, 03SC). 09020302 ｨｨ0409ｨｲ080302ｨｪ06 ｨｰｨｲ080902ｨｪ02 ｨｪｨ 09070202ｨｨ00ｨｨ ﾂｨｪｨ 05ｨｨｨｰ0208ｨ ｨｰｨｮ08ｨ 0608ｨｨ00ｨｨｨｪｨ 05ｨｪｨｨ 09ｨｰｨ ｨｰｨｨｨｨ 06ｨｰ 080201ｨ ｨｺｨｰｨｨ08ｨ ｨｪｨｨ 0907ｨｨ09ｨ ｨｪｨｨ07, 09ｨｺ0506 ﾂ02ｨｪｨｨ 09 Medline. 02090902ｨｪ ｨｰ0609ｨ ｨ 0701ｨ 07080200050201ｨ ｨｪｨｨ 09ｨｪｨｨｨｬｨ ｨｰ0205ｨｪ06 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｰｨ ｨｪｨ 030208 ｨｨ ｨｪｨ 08ｨｬ0208ｨｨｨｺｨ ｨｪ09ｨｺｨ ｨｰｨ 09ｨｲ080102 ﾂｨｪｨ ｨ 090602ｨｨｨ 02ｨｨ07 / 08ｨｬ0208ｨｨｨｺｨ ｨｪ09ｨｺｨｨ07 ｨｺ06050203 0706 ｨｺｨ 0801ｨｨ06050600ｨｨ07, 09ｨｺ0506 ﾂ09ｨ ｨｴｨｨ 070802070608ｨｲｨｺｨｨ 04ｨ 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ ACE-I. 03060902 ﾂ02ｨｰ06 06ｨｰ 07080201ｨｨ03ｨｪｨｨｨｰ02 070802070608ｨｲｨｺｨｨ ｨ 0701ｨ 04ｨ 07ｨ 0402ｨｪｨｨ, ｨｪ07ｨｺ06ｨｨ ｨ 0701ｨ 0609ｨｲ090802ｨｬ02ｨｪ02ｨｪｨｨ ｨｨ ｨｪ07ｨｺ0605ｨｺ06 09ｨ ｨｪ0609ｨｨ 09 09ｨｲ06ｨｰ0902ｨｰ09ｨｰ09ｨｨ02 09 070609050201ｨｪｨｨｨｰ02 05ｨｨｨｰ0208ｨ ｨｰｨｮ08ｨｪｨｨ 01ｨ ｨｪｨｪｨｨ. 06040706050409ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨｺｨ ｨｰ0200o08ｨｨ04ｨｨ08ｨ ｨｪｨｨ 070802070608ｨｲｨｺｨｨ 0609ｨｨ00ｨｮ080709ｨ 07080609ｨｰ ｨｬ02ｨｰ0601 04ｨ ｨｮ07ｨｲｨｰ09ｨ ｨｪ02. 0805ｨ 09060902ｨｰ02 070802070608ｨｲｨｺｨｨ 09ｨ ｨｨ04090502 ﾂ02ｨｪｨｨ 06ｨｰ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07, 07080609020102ｨｪｨｨ 0708ｨｨ 070601ｨ 08ｨ ｨｪｨｨ 0008ｨｮ07ｨｨ 06ｨｰ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ, ｨｺ06ｨｨｨｰ06 ｨｬ060302 01ｨ ｨｪ02 09ｨ 0708020109ｨｰｨ 09ｨｨｨｰ0205ｨｪｨｨ 04ｨ 0706-03ｨｨ0806ｨｺｨｨ 070607ｨｮ05ｨ 02ｨｨｨｨ; 0909ｨｲｨｴｨｪ0609ｨｰ 07ｨ 02ｨｨ02ｨｪｨｰｨｨｨｰ02 09 070806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ07 0902 ｨｨ04ｨｺ0506 ﾂ09ｨ ｨｰ 06ｨｰ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨｨｰ02 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07. 02090902ｨｪ ｨｰ0609ｨ 0201ｨｪｨ ｨｨ 09ｨｲｨｴｨ 09ｨｨ05ｨ ｨｪｨ 0106ｨｺｨ 04ｨ ｨｰ020509ｨｰ09ｨ ｨｰｨ ｨｬ060302 01ｨ 06ｨｰ08ｨ 040709ｨ 08ｨ 0405ｨｨ ﾂｨｪｨｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 07060504ｨｨ: 09ｨｬｨｲ08ｨｰｨｪ0609ｨｰ, ｨ 06050209ｨｰｨｪ0609ｨｰ, ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 09ｨｨｨｬ07ｨｰ06ｨｬｨｨ ｨｨ05ｨｨ ｨｺ06ｨｬｨ ｨｨｨｪｨｨ08ｨ ｨｪｨｨ ｨｺ08ｨ ｨｦｨｪｨｨ 0706ｨｺｨ 04ｨ ｨｰ0205ｨｨ; 00060502ｨｬｨｨ ｨｨ05ｨｨ ｨｬｨ 05ｨｺｨｨ 07060504ｨｨ, ｨｬｨ ｨｺｨ 08 ｨｨ 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｨ 04ｨｪｨ ﾂｨｨｨｬｨｨ; 050209ｨｪ06 070609ｨｰｨｨ00ｨ ｨｴｨｨ 0902 ｨｨ05ｨｨ 09ｨ ｨｬ06 ｨｪｨ ｨ 050601ｨ 09ｨ ｨｪｨｨ 07060504ｨｨ, ｨｨ05ｨｨ ｨｺ08ｨ ｨｰｨｺ06ｨｰ08ｨ ｨｦｨｪｨｨ 020002ｨｺｨｰｨｨ, ｨｺ06ｨｨｨｰ06 0902 00ｨｮｨ 07ｨｰ 09050201 ｨｪ07ｨｺ0605ｨｺ06 000601ｨｨｨｪｨｨ 0502 ﾂ02ｨｪｨｨ02. 01ｨ 070609050201ｨｪ06 ｨｬ0709ｨｰ06, 09 06ｨｰ010205ｨｪｨｨ 0905ｨｮ- ﾂｨ ｨｨ 070802070608ｨｲ ﾂ09ｨ ｨｪｨ ｨｰｨ ｨｰ0208ｨ 07ｨｨ07 ｨｬ060302 01ｨ 02 09ｨ ｨｬ06 0201ｨｪｨ 06ｨ ｨ 05ｨｨ02ｨ 1. 030002ｨｺｨｰｨｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 05ｨｲ01060902 05ｨｲ080202 01ｨ 01ｨ ｨｲｨ 0802 ﾂｨｪｨ 03050204ｨ 000604ｨｲｨｺ 09ｨｲｨ 0802ｨｺ 060806ｨｬｨ 0602ｨｨｨｰｨｨ 03ｨｪ0106ｨｰ0205ｨｪｨｨ ｨｺ0502ｨｰｨｺｨｨ 05ｨｨｨｬ07ｨ ｨｰｨｨｨｺｨｮ090609 ｨｰ06ｨｪｨｮ09 00ｨ 0406ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺ02ｨｨ07 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 06090906ｨ 060301ｨ 09ｨ ｨｪ02ｨｰ06 ｨｪｨ noradrenalin, aldosteron, vasopressin ｨｨ endoth02lin-1 06ｨｪ06ｨｰ08060702ｨｪ ｨｨ 010806ｨｪ06ｨｰ08060702ｨｪ 020002ｨｺｨｰ 08060806ｨｪｨ 08ｨｪｨ 09ｨ 0406ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺ02ｨｨ07 02090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ ｨ 05010609ｨｰ020806ｨｪ ｨｨ ｨ 010802ｨｪｨ 05ｨｨｨｪ 02090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ 09ｨ 040607080209ｨｨｨｪ 02090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ 09ｨｮｨ 09ｨｰｨ ｨｪ02ｨｨ07 P, LHRH ｨｨ ACTH 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 0202ｨｪｨｰｨｲ08ｨ ｨｪｨ 03ｨ 0301ｨ ｨｰｨ 030609ｨｨ0302ｨｪ06 09ｨｨｨｬ07ｨ ｨｰｨｨｨｺｨｮ09060906 ｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 00ｨ 0406ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺ02ｨｨ07 (0200020802ｨｪｨｰｨｪｨ > ｨ 00020802ｨｪｨｰｨｪｨ ｨ 08ｨｰ0208ｨｨ0605ｨ ) 0806ｨｪｨｰ08ｨ 01ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨｬ0204aｨｪ00ｨｨｨ 05ｨｪｨｨｨｰ02 ｨｺ0502ｨｰｨｺｨｨ 030609ｨｨ0302ｨｪｨ 0802ｨ ｨ 09060802ｨｨ07 ｨｪｨ Na 09 070806ｨｺ09ｨｨｨｬｨ 05ｨｪｨｨ07 ｨｰｨｮｨ ｨｮ05 030609ｨｨ0302ｨｪｨ 02ｨｺ09ｨｺ080202ｨｨ07 ｨｪｨ 08 09 01ｨｨ09ｨｰｨ 05ｨｪｨｨ07 ｨｪ02000806ｨｪ 01ｨ ｨｬｨ 0502ｨｪ06 06090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ 0802ｨｪｨｨｨｪ 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ ｨｰ0806ｨｬｨ 0602ｨｨｨｰｨｪｨ ｨｰｨ ｨ 01010204ｨｨ07 ｨｨ ｨ 00080200ｨ 02ｨｨ07 06ｨｪｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 ｨｪｨ NO (ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ 09ｨｨｨｪｨｰ02ｨｰｨ 04ｨ ｨｰｨ ｨｪｨ ｨ 0406ｨｰ02ｨｪ 06ｨｺｨｨ09 09 02ｨｪ0106ｨｰ0205ｨ ) 03ｨｺ0907080209ｨｨ07 ｨｪｨ 02ｨｪ0106ｨｰ0205ｨｪｨｨ07 0802020207ｨｰ0608 04ｨ oxldl (LOX-1) 0709ｨｨ0509ｨ ｨｪ02 ｨｪｨ 070208ｨｨ000208ｨｪｨ ｨｰｨ ｨｪ0608ｨ 010802ｨｪ020800ｨｨ ﾂｨｪｨ ｨｪ02090806ｨｰ08ｨ ｨｪ09ｨｬｨｨ09ｨｨ07 02090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ ｨｺｨ ｨｰ02010605ｨ ｨｬｨｨｨｪｨｨ 06ｨｰ ｨｪｨ 01ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ ｨｬ0201ｨｮ05ｨ 08ｨｨｨ 08ｨｨｨｪ0605ｨｨ04ｨ 030609ｨｨ0302ｨｪｨ 02ｨｺ0907080209ｨｨ07 ｨｪｨ PAI-1 ｨｨ 2 00ｨｲ0407ｨ 0502ｨｪｨｨ02 06080600ｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 08ｨｰ02080609ｨｺ0502080604ｨ 08ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 ｨｨ ｨｬｨｨ0008ｨ 02ｨｨ07 ｨｪｨ ｨｬｨ ｨｺ080600ｨ 00ｨｨｨｰ02 030609ｨｨ0302ｨｪｨ 02ｨｺ0907080209ｨｨ07 ｨｪｨ ｨ 01010204ｨｨ06ｨｪｨｪｨｨ ｨｬ060502ｨｺｨｮ05ｨｨ (VCAM-1, ICAM-1, P-selectin), 0102ｨｬ06ｨｰｨ ｨｺ09ｨｨ09ｨｪｨｨ 070806ｨｰ02ｨｨｨｪｨｨ (MCP-1) ｨｨ 02ｨｨｨｰ06ｨｺｨｨｨｪｨｨ (IL-6) 09ｨｨ070208ｨｰ080600ｨｨ07 ｨｪｨ ｨｺｨ 0801ｨｨ06ｨｬｨｨ0602ｨｨｨｰｨｨｨｰ02 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 0005ｨ 01ｨｺ06ｨｬｨｮ09ｨｺｨｮ05ｨｪｨ ｨｰｨ ｨｬｨｨ0008ｨ 02ｨｨ07, 07080605ｨｨ000208ｨ 02ｨｨ07 ｨｨ 01ｨｨ070208ｨｰ080600ｨｨ07 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 070806ｨｰ06-06ｨｪｨｺ060002ｨｪｨｨｨｰ02 (fos, myc, jun) ｨｨ MAPKs (ERKs ｨｨ JNK) 030609ｨｨ0302ｨｪ06 070806ｨｨ0409060109ｨｰ0906 ｨｪｨ 08ｨ 09ｨｰ0203ｨｪｨｨ 00ｨ ｨｺｨｰ0608ｨｨ (PDGF, bfgf, IGF-1, TGFｦﾂ1 ｨｨ ｦﾂ2) 030609ｨｨ0302ｨｪ 09ｨｨｨｪｨｰ0204 ｨｪｨ 02ｨｺ09ｨｰ08ｨ 020205ｨｮ05ｨ 08ｨｪｨｨ ｨｬｨ ｨｰ08ｨｨｨｺ09ｨｪｨｨ 070806ｨｰ02ｨｨｨｪｨｨ (00ｨｨｨ 0806ｨｪ02ｨｺｨｰｨｨｨｪ, ｨｺ0605ｨ 0002ｨｪ ｨｰｨｨ07-I ｨｨ III, 05ｨ ｨｬｨｨｨｪｨｨｨｪ-ｦﾂ1 ｨｨ ｦﾂ2) ｨｨ ｨｬ02ｨｰｨ 0506070806ｨｰ02ｨｨｨｪｨ 04ｨｨ 05ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ NADH/NADPH-06ｨｺ09ｨｨ01ｨ 04ｨｪｨ ｨｰｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰ ｨｨ 070806ｨｨ0409060109ｨｰ0906ｨｰ06 ｨｪｨ 09ｨｮ07020806ｨｺ09ｨｨ0102ｨｪ ｨ ｨｪｨｨ06ｨｪ, 05ｨｨ07ｨｨ01ｨｪｨ ｨｰｨ 07020806ｨｺ09ｨｨ01ｨ 02ｨｨ07 ACTH=ｨ 010802ｨｪ06ｨｺ0608ｨｰｨｨｨｺ06ｨｰ08060702ｨｪ 010608ｨｬ06ｨｪ; bfgf=ｨ ｨ 04ｨｨ0902ｨｪ 00ｨｨｨ 0806ｨ 05ｨ 09ｨｰ02ｨｪ 08ｨ 09ｨｰ020302ｨｪ 00ｨ ｨｺｨｰ0608; ERKs=02ｨｺ09ｨｰ08ｨ 020205ｨｮ05ｨ 08ｨｪｨｨ 09ｨｨ00ｨｪｨ 05-080200ｨｮ05ｨｨ08ｨ ｨｪｨｨ 070806ｨｰ02ｨｨｨｪｨｺｨｨｨｪｨ 04ｨｨ; JNK=Jun N-ｨｰ0208ｨｬｨｨｨｪｨ 05ｨｪｨｨ ｨｺｨｨｨｪｨ 04ｨｨ; LHRH=06090906ｨ 060301ｨ 09ｨ ｨｴ 010608ｨｬ06ｨｪ ｨｪｨ 05ｨｮｨｰ02ｨｨｨｪｨｨ04ｨｨ08ｨ ｨｴｨｨ07 010608ｨｬ06ｨｪ; ICAM=09ｨｲｨｰ0802ｨｺ0502ｨｰｨｲ ﾂｨｪｨ ｨ 01010204ｨｨ06ｨｪｨｪｨ ｨｬ060502ｨｺｨｮ05ｨ ; IGF-1= ｨｨｨｪ09ｨｮ05ｨｨｨｪ0607060106ｨ 02ｨｪ 08ｨ 09ｨｰ020302ｨｪ 00ｨ ｨｺｨｰ0608; IL-6=ｨｨｨｪｨｰ0208050209ｨｺｨｨｨｪ 6; LOX-1=05ｨｨ070606ｨｺ09ｨｨ0002ｨｪｨ 04ｨ -1; MCP-1=ｨｬ06ｨｪ0602ｨｨｨｰ02ｨｪ 0102ｨｬ06ｨ ｨｰ08ｨ ｨｺｨｰｨ ｨｪｨｰ02ｨｪ 070806ｨｰ02ｨｨｨｪ 1;MAPKs=ｨｬｨｨｨｰ060002ｨｪ-ｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪｨｨ 070806ｨｰ02ｨｨｨｪｨｺｨｨｨｪｨ 04ｨｨ; PDGF=ｨｰ0806ｨｬｨ 0602ｨｨｨｰ02ｨｪ 08ｨ 09ｨｰ020302ｨｪ 00ｨ ｨｺｨｰ0608;NADP/NADPH=ｨｪｨｨｨｺ06ｨｰｨｨｨｪｨ ｨｬｨｨ01 ｨ 0102ｨｪｨｨｨｪ 01ｨｨｨｪｨｮｨｺ050206ｨｰｨｨ01 / ｨｪｨｨｨｺ06ｨｰｨｨｨｪｨ ｨｬｨｨ01 ｨ 0102ｨｪｨｨｨｪ 01ｨｨｨｪｨｮｨｺ050206ｨｰｨｨ01 00060900ｨ ｨｰ; NO=ｨ 0406ｨｰ02ｨｪ 06ｨｺｨｨ09; PAI=ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608 ｨｪｨ ｨ ｨｺｨｰｨｨ09ｨ ｨｰ0608ｨ ｨｪｨ 0705ｨ 04ｨｬｨｨｨｪ060002ｨｪｨ ; TGF=ｨｰ08ｨ ｨｪ09000608ｨｬｨｨ08ｨ ｨｴ 08ｨ 09ｨｰ020302ｨｪ 00ｨ ｨｺｨｰ0608; VCAM=09ｨｲ01060906ｨｺ0502ｨｰｨｲ ﾂｨｪｨ ｨ 01010204ｨｨ06ｨｪｨｪｨ ｨｬ060502ｨｺｨｮ05ｨ. 4
1306ｨｰ 09ｨｲ04ｨｬ0603ｨｪ0609ｨｰｨｨｨｰ02 ｨｨ 0108ｨｮ00ｨｨｨｰ02 ｨ 05ｨｰ0208ｨｪｨ ｨｰｨｨ09ｨｨ 01ｨ 09ｨ 0201ｨｪｨ ｨｺ0906 0708ｨｨ02ｨｬ05ｨｨ09ｨｨ, 010608ｨｨ 0706-07060101060107ｨｴｨｨ. 090701ｨ 070605060302ｨｪｨｨ ｨｮ09ｨｨ05ｨｨ07 ｨｰｨ 04ｨｨ ｨｨｨｪ000608ｨｬｨ 02ｨｨ07 01ｨ ｨ ｨｲ0102 09ｨｺ0506- ﾂ02ｨｪｨ 09 06ｨｰｨｪ0609ｨｨｨｰ0205ｨｪ06 ｨｺ08ｨ ｨｰｨｲｨｺ 0106ｨｺｨｮｨｬ02ｨｪｨｰ. 06040006ｨｰ0902ｨｪｨｨ07ｨｰ 06ｨｰ 08ｨ ｨ 06ｨｰｨｪｨ ｨｰｨ 0008ｨｮ07ｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰ ｨ 020302 070802010609ｨｰｨ 0902ｨｪ ｨｪｨ 080201ｨ ｨｺ02ｨｨ06ｨｪｨｪｨ ｨｺ06ｨｬｨｨ09ｨｨ07, ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨ 06ｨｰ 030208 ｨｨ 060106ｨ 0802ｨｪ 06ｨｰ ｨｺ06ｨｬｨｨｨｰ02ｨｰｨ 04ｨ 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨｨ 08ｨｲｨｺ0609060109ｨｰ09ｨ ｨｪｨ 030208. 02ｨｺ06ｨｪ ﾂｨ ｨｰ0205ｨｪｨｨ07ｨｰ 0106ｨｺｨｮｨｬ02ｨｪｨｰ ｨ 020302 ｨｨ040708ｨ ｨｰ02ｨｪ 09 European Heart Journal 04ｨ 0600ｨｨ02ｨｨｨ 05ｨｪｨ 08020202ｨｪ04ｨｨ07. 060604ｨｨ ｨｺ06ｨｪ0902ｨｪ09ｨｮ0902ｨｪ 0106ｨｺｨｮｨｬ02ｨｪｨｰ 0708020109ｨｰｨ 0907 090109ｨ ｨｴｨ ｨｪｨｨ07ｨｰｨ ｨｪｨ 030208 ｨｨ ｨ 020302 ｨｨ040006ｨｰ0902ｨｪ 09050201 09ｨｪｨｨｨｬｨ ｨｰ0205ｨｪ06 08ｨ 040005020301ｨ ｨｪ02 ｨｪｨ ｨｪｨ 05ｨｨ ﾂｨｪｨｨｨｰ02 01ｨ ｨｪｨｪｨｨ. 02ｨｰ 0502ｨｺｨ 08ｨｨｨｰ02 0902 06 ﾂｨ ｨｺ09ｨ 01ｨ 0902 09ｨｲ06ｨ 08ｨ 040709ｨ ｨｰ ｨｪｨ 07ｨｲ05ｨｪ06 09 ｨｪ020006 0708ｨｨ 090402ｨｬｨ ｨｪ02 ｨｪｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 08020302ｨｪｨｨ07. 060604ｨｨ 0106ｨｺｨｮｨｬ02ｨｪｨｰ ｨｪ02 06ｨｰｨｬ02ｨｪ07 ｨｨｨｪ01ｨｨ09ｨｨ01ｨｮｨ 05ｨｪｨ ｨｰｨ 06ｨｰ0006090608ｨｪ0609ｨｰ ｨｪｨ 0502ｨｺｨ 0807 04ｨ 090402ｨｬｨ ｨｪ02 ｨｪｨ 0708ｨ 09ｨｨ05ｨｪｨｨ 08020302ｨｪｨｨ07 090706080201 06ｨ 09ｨｰ0607ｨｰ020509ｨｰ09ｨ ｨｰｨ 0708ｨｨ 090902ｨｺｨｨ 06ｨｰ01020502ｨｪ 07ｨ 02ｨｨ02ｨｪｨｰ, 09050201 06ｨ 09ｨｲ0301ｨ ｨｪ02 09 07ｨ 02ｨｨ02ｨｪｨｰｨ, a ｨｺ0600ｨ ｨｰ06 02 ｨｮｨｬ0209ｨｰｨｪ06 ｨｨ ｨｪｨ 050603ｨｨｨｰ0205ｨｪ06, 09 ｨｪｨ 09ｨｰ06ｨｦｨｪｨｨｨｺｨ ｨｨ05ｨｨ 05ｨｨ0202ｨｰ06, 070605ｨ 00ｨ ｨｴ06 0008ｨｨ03ｨｨ 04ｨ 07ｨ 02ｨｨ02ｨｪｨｰｨ. 08ｨ 08ｨｬｨ ｨｺ06050600ｨｨ07 0207080201020502ｨｪｨｨ02 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨｨｰ02 (ACE-I) ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｰ ｨｺ06ｨｪｨｺｨｮ0802ｨｪｨｰｨｪ06 ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ ｨｺ06ｨｪ090208ｨｰｨｨ08ｨ ｨｴｨｨ07 02ｨｪ04ｨｨｨｬ. 1-3 ACE 02 ｨｪ0209070202ｨｨ00ｨｨ ﾂ02ｨｪ 02ｨｪ04ｨｨｨｬ, ｨｮ ﾂｨ 09ｨｰ09ｨ ｨｴ 09 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬｨ ｨｪｨ ｨｬｨｪ060006 ｨｬｨ 05ｨｺｨｨ 070207ｨｰｨｨ01ｨｨ, 09ｨｺ0506 ﾂｨｨｨｰ0205ｨｪ06 0708020908ｨｲｨｴｨ ｨｪ02ｨｰ06 ｨｪｨ ｨｪ02ｨ ｨｺｨｰｨｨ09ｨｪｨｨ07 06ｨｺｨｰｨ 070207ｨｰｨｨ01 ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ I 09 ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II. ACE-I ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｰ ｨｺ06ｨｪｨｺｨｮ0802ｨｰｨｪ06 ｨｨ 02ｨｪ04ｨｨｨｬｨ ｨｺｨｨｨｪｨｨｨｪｨ 04ｨ, ｨｺ06ｨｦｨｰ06 ｨｺｨ ｨｰｨ 05ｨｨ04ｨｨ08ｨ 08ｨ 040008ｨ 0301ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ ｨｨ 0108ｨｮ00ｨｨ ｨｬ06ｨｴｨｪｨｨ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｪｨｨ 070207ｨｰｨｨ01ｨｨ. 0209ｨｪ0609ｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 09ｨ 06ｨ 06ｨ ｨｴ02ｨｪｨｨ 09 ｨｰｨ ｨ 05. 1. 0805ｨ 09ｨｨ00ｨｨｨｺｨ 02ｨｨ07 ｨｪｨ ACE-I 050706080201 0008ｨｮ07ｨ ｨｰｨ, 0909ｨｲ0804ｨ ｨｪｨ 09 02ｨｨｨｪｨｺ0609ｨｨ07 ｨ ｨｰ06ｨｬ 09 ｨｬ060502ｨｺｨｮ05ｨ ｨｰｨ ｨｨｨｬ, ACE-I 09ｨ ｨｺ05ｨ 09ｨｨ00ｨｨ02ｨｨ08ｨ ｨｪｨｨ 09 ｨｰ08ｨｨ ｨｺｨ ｨｰ02000608ｨｨｨｨ: ｨｪｨ 09ｨｲ01ｨｲ0803ｨ ｨｴｨｨ 09ｨｮ0500ｨｨ0108ｨｨ05ｨｪｨ, ｨｺｨ 08ｨ 06ｨｺ09ｨｨ05ｨｪｨ ｨｨ05ｨｨ 000609000608ｨｨ05ｨｪｨ 0008ｨｮ07ｨ ｨｺｨ ｨｰ06 05ｨｨ00ｨ ｨｪ01 ｨｪｨ 02ｨｨｨｪｨｺｨ (ｨｰｨ ｨ 05. 2). 4 08ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨ ﾂ02ｨｪ 07080600ｨｨ05 08ｨ 090608ｨ 02ｨｨ07ｨｰｨ ｨｪｨ 08ｨ 0405ｨｨ ﾂｨｪｨｨｨｰ02 ACE-I 09ｨ 08ｨｨ08ｨ 04ｨｪｨ - ﾂｨｨｨｰ0205ｨｪ06 (25-75%), ｨｺｨ ｨｰ06 0108ｨ ｨｪｨ ｨｰｨ ｨｨ05ｨｨ ｨｪ02 06ｨｺｨ 0409ｨ 0905ｨｨ07ｨｪｨｨ02 ｨｨ05ｨｨ ｨｪｨ ｨｬｨ 050709ｨ 09ｨｺo080609ｨｰｨｰｨ, ｨｪ06 ｨｪ02 ｨｨ 09ｨｰ020702ｨｪｨｰｨ ｨｪｨ ｨ ｨ 090608ｨ 02ｨｨ07. 0107ｨｺ06ｨｨ ACE-I 09ｨ 070802ｨｺｨｮ08090608ｨｨ (pro-drugs) ｨｨ 0609ｨｰｨ 09ｨ ｨｰ ｨｪ02ｨ ｨｺｨｰｨｨ09ｨｪｨｨ, 0106ｨｺｨ ｨｰ06 ｨｪ02 ｨ ｨｲ01ｨ ｨｰ 07080209ｨｲ08ｨｪｨ ｨｰｨｨ 09 ｨ ｨｺｨｰｨｨ09ｨｪｨｨ ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰｨｨ ﾂ080204 01ｨｨ01080605ｨｨ04ｨ 09 ﾂ0208ｨｪｨｨ07 010806ｨ ｨｨ05ｨｨ ｨｰｨｲｨｺｨ ｨｪｨｨｨｰ02 ｨｪｨ 00ｨ 09ｨｰ0806ｨｨｨｪｨｰ0209ｨｰｨｨｨｪｨ 05ｨｪｨｨ07 ｨｰ08ｨ ｨｺｨｰ. 1-3 00ｨ ｨｺ09ｨｨｨｬｨ 05ｨｪｨｨｨｰ02 0705ｨ 04ｨｬ02ｨｪｨｨ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨ 0902 010609ｨｰｨｨ00ｨ ｨｰ 1-4 ﾂｨ 09ｨ 09050201 0708ｨｨ02ｨｬｨ. 030802ｨｺｨｮ08090608ｨｨｨｰ02 09ｨ 0706-05ｨｨ070600ｨｨ05ｨｪｨｨ ｨｨ ｨｨｨｬｨ ｨｰ 0706-0106ｨ ｨｲ08 010609ｨｰｨｲ07 0106 0708ｨｨ020205ｨｪｨｨｨｰ02 ｨｰｨｲｨｺｨ ｨｪｨｨ, ｨｺｨｲ0102ｨｰ06 0902 0708020908ｨｲｨｴｨ ｨｰ 09 ｨ ｨｺｨｰｨｨ09ｨｪｨｨ 09ｨｲ0201ｨｨｨｪ02ｨｪｨｨ07. 03060902 ﾂ02ｨｰ06 ACE-I ｨｨ ｨｰ0201ｨｪｨｨｨｰ02 ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰｨｨ ｨｨｨｬｨ ｨｰ 07080201ｨｨｨｬｨｪ06 ｨ ｨｲｨ 0802 ﾂｨｪｨ 02ｨｺ09080202ｨｨ07, 0106ｨｺｨ ｨｰ06 Fosinopril, Zofenopril, Trandolapril ｨｨ Spirapril 0902 01ｨ 08ｨ ｨｺｨｰ0208ｨｨ04ｨｨ08ｨ ｨｰ 09 ｨ ｨ 05ｨ ｨｪ09ｨｨ08ｨ ｨｪ06 ﾂ0208ｨｪ06010806ｨ ｨｪ06 ｨｨ ｨ ｨｲｨ 0802 ﾂｨｪ06 0205ｨｨｨｬｨｨｨｪｨｨ08ｨ ｨｪ02. 5 Captopril 0902 0205ｨｨｨｬｨｨｨｪｨｨ08ｨ 0706-ｨ ｨｲ080406 06ｨｰ 060800ｨ ｨｪｨｨ04ｨｬｨ, ｨｺ0602ｨｰ06 e 0708ｨｨ- ﾂｨｨｨｪｨ 04ｨ ｨｪ02000609ｨ ｨｰｨ ｨｺ08ｨ ｨｰｨｺｨ 07080601ｨｲ0503ｨｨｨｰ0205ｨｪ0609ｨｰ ｨｪｨ 0102ｨｦ09ｨｰ09ｨｨ02 (<6 h), 0106ｨｺｨ ｨｰ06 Ramiprilat (ｨ ｨｺｨｰｨｨ09ｨｪｨｨ07ｨｰ ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰ ｨｪｨ Ramipril ｨｨ 060906ｨ 02ｨｪ06 Trandolaprilat 0902 06ｨ ｨ 05ｨｨ02ｨ 2. 08ｨ 08ｨｬｨ ｨｺ06050600ｨｨ ﾂｨｪｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｪｨ 08ｨ 0405ｨｨ ﾂｨｪｨｨｨｰ02 ACE-I 000201ｨｨｨｺｨ ｨｬ02ｨｪｨｰ 030605ｨｮ03ｨｨ0906ｨｰ ｨｪｨ 09ｨｲｨ 0802 ﾂｨｪ06 02ｨｪ0209ｨｪｨ 010604ｨ (mg) 0206040609 080203ｨｨｨｬ (mg) 0205ｨｨｨｬｨｨｨｪｨｨ08ｨ ｨｪ02 0205ｨｨｨｬｨｨｨｪｨｨ08ｨ ｨｪ02 09ｨｰｨ ｨｪ01ｨ 08ｨｰ02ｨｪ 0708ｨｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ (%) 080203ｨｨｨｬ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ CrCl 10-30 ml/min 080503-I, 09ｨｲ01ｨｲ0803ｨ ｨｴｨｨ 09ｨｮ050001ｨｨ0108ｨｨ05ｨｪｨ 0008ｨｮ07ｨ Benazepril* 11 85 2 x 2,5-20 2 x 2,5-10 Captopril 2 95 3 x 25-100 3 x 6,25-12,5 Zofenopril* 4,5 60** 2 x 7,5-30 2 x 7,5-30 080503-I, 09ｨｲ01ｨｲ0803ｨ ｨｴｨｨ ｨｺｨ ｨ 06ｨｺ09ｨｨ05ｨｪｨ 0008ｨｮ07ｨ Cilazapril 10 80 1,25-5 0,5-2,5 Enalapril* 11 88 2 x 2,5-20 2 x 2,5-20 Lisinopril* 12 70 2,5-10 2,5-5 Perindopril* >24 75 4-8 2 Quinapril* 2-4 75 10-40 2,5-5 Rami pril* 8-14 85 2,5-10 1,25-5 Spirapril 1,6 50** 3-6 3-6 Trandolapril 16-24 15** 1-4 0,5-1 080503-I, 09ｨｲ01ｨｲ0803ｨ ｨｴｨｨ 00060900ｨｨｨｪｨｨ05ｨｪｨ 0008ｨｮ07ｨ Fosinopril* 12 50** 10-40 10-40 CrCl =ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪ0609 ｨｺ05ｨｨ08ｨｲｨｪ09* 030802ｨｺｨｮ08090608** 05ｨｪｨ ﾂｨｨｨｰ0205ｨｪ06 ﾂ0208ｨｪ06010806ｨ ｨｪ06 0205ｨｨｨｬｨｨｨｪｨｨ08ｨ ｨｪ02 5
130205ｨｨｨｬｨｨｨｪｨｨ08ｨ ｨｰ 0706-ｨ ｨ 09ｨｪ06 06ｨｰ 0609ｨｰｨ ｨｪｨ 05ｨｨｨｰ02 ACE-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608ｨｨ (ｨｰｨ ｨ 05. 2). 0308ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09ｨｲ09 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501 060008ｨ ｨｪｨｨ ﾂ02ｨｪｨ ｨｰｨ ｨ ｨ 090608ｨ 02ｨｨ07 ｨｨ ｨ ｨｨ06ｨｰ08ｨ ｨｪ09000608ｨｬｨ 02ｨｨ07 ｨｬ060302 01ｨ 04ｨ ｨ ｨ 09ｨｨ ｨｪｨ ﾂｨ 0506ｨｰ06 ｨｪｨ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｨ07 020002ｨｺｨｰ. 030608ｨ 01ｨｨ ｨｪｨ ｨｬｨ 0502ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ 07020800ｨｮ04ｨｨ07, ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ 02ｨｺ09ｨｺ080202ｨｨ07 ｨｬ060302 01ｨ ｨ ｨｲ0102 060008ｨ ｨｪｨｨ ﾂ02ｨｪｨ ｨｨ ｨｰ0609ｨ 01ｨ 010609020102 0106 070609ｨｨ0302ｨｪｨｨ ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｪｨｨ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｨ 0705ｨ 04ｨｬ02ｨｪｨｨ ｨｪｨｨ09ｨ ｨｨ ｨｮ01ｨｲ050302ｨｪ06 0102ｨｦ09ｨｰ09ｨｨ02. 050502010609ｨ ｨｰ0205ｨｪ06 0708ｨｨ ｨｮ0908020102ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ 00ｨｮｨｪｨｺ02ｨｨ07 (ｨｺ0600ｨ ｨｰ06 ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪ0609ｨｨ07ｨｰ ｨｺ05ｨｨ08ｨｲｨｪ09 0907ｨ 01ｨｪ02 05 30 ml/min) 0902 ｨｪｨ 05ｨ 00ｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｪ02 ｨｪｨ 010604ｨｨｨｰ02. 5 Fosinopril, Sprirapril, Trandolapril ｨｨ Zofenopril ｨｨｨｬｨ ｨｰ 010906ｨｦｨｪｨ 02ｨｺ09ｨｺ080202ｨｨ07 09 ｨｮ08ｨｨｨｪｨ ｨｰｨ ｨｨ 0305ｨｲ ﾂｨｺｨ ｨｰｨ, ｨｰｨ ｨｺｨ ﾂ02 ｨｰ0201ｨｪｨｨ07ｨｰ ｨｺ05ｨｨ08ｨｲｨｪ09 ｨｪ02 0902 070806ｨｬ02ｨｪ07 09ｨｲｨｴ0209ｨｰ0902ｨｪ06 0708ｨｨ ｨ ｨｲｨ 0802 ﾂｨｪ06 ｨｮ0908020301ｨ ｨｪ02 (ｨｰｨ ｨ 05. 2). 000201ｨ ｨｪｨｨ04ｨｲｨｬ ｨｪｨ 0102ｨｦ09ｨｰ09ｨｨ02 ACE-I ｨｺ06ｨｪｨｺｨｮ0802ｨｪｨｰｨｪ06 ｨ 0506ｨｺｨｨ08ｨ ｨｰ 0708020908ｨｲｨｴｨ ｨｪ02ｨｰ06 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ I 09 ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II ｨｨ 0706ｨｪｨｨ03ｨ 09ｨ ｨｰ 02ｨｨ08ｨｺｨｮ05ｨｨ08ｨ ｨｴｨｨｨｰ02 ｨｨ 0506ｨｺｨ 05ｨｪｨｨ ｨｪｨｨ09ｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II. ACE-I 060008ｨ ｨｪｨｨ ﾂｨ 09ｨ ｨｰ ｨｨ 0902ｨｺ080202ｨｨ07ｨｰｨ ｨｪｨ ｨ 05010609ｨｰ020806ｨｪ ｨｨ 09ｨ 040607080209ｨｨｨｪ ｨｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 09ｨｨｨｬｨ ｨｰｨｨｨｺｨｮ090609ｨ ｨｰｨ ｨｪ020809ｨｪｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰ, ｨｺｨ ｨｺｨｰ06 ｨｨ ｨｰ080600ｨｨ ﾂｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II. ﾁ080204 ｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 ｨｪｨ 0806 1 ｨｨ 0806 2-0802020207ｨｰ0608ｨｨｨｰ02, ｨｰe ｨｪ02 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｰ 020002ｨｺｨｰｨｨｨｰ02 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II ｨｨ ｨｪ02 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨ ｨｰ 01ｨｨ0802ｨｺｨｰｨｪ06 09 0108ｨｮ00ｨｨ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰｨｨ ｨｪｨ 040805. 1-4,6,2 02090902ｨｪ ｨｰ0609ｨ ACE-I ｨｬ0600ｨ ｨｰ 01ｨ ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｰ ｨｨ ｨｺｨｨｨｪｨｨｨｪｨ 04ｨ II ｨｨ 01ｨ 070609ｨｨ03ｨ 09ｨ ｨｰ ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪｨ, ｨｺ06ｨｦｨｰ06 06ｨｰ 09090607 09ｨｰ08ｨ ｨｪｨ 09ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 00 2-0802020207ｨｰ0608ｨｨｨｰ02 ｨｨ 090601ｨｨ 0106 06090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ NO ｨｨ 09ｨ 0406ｨ ｨｺｨｰｨｨ09ｨｪｨｨ 07080609ｨｰｨ 0005ｨ ｨｪ01ｨｨｨｪｨｨ (07080609ｨｰｨ 02ｨｨｨｺ05ｨｨｨｪｨｨ ｨｨ 07080609ｨｰｨ 0005ｨ ｨｪ01ｨｨｨｪ 03 2 ). 8.9 0308ｨｨ 010806ｨｪｨｨ ﾂｨｪ06 0708ｨｨ05060302ｨｪｨｨ02 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02ｨｰ06 ｨｪｨ 0705ｨ 04ｨｬ02ｨｪｨｨ07 08CE ｨｨ040005020301ｨ ｨｨｨｬｨ 0706-ｨｬｨ 05ｨｺ06 04ｨｪｨ ﾂ02ｨｪｨｨ02, 0106ｨｺｨ ｨｰ06 0706-09ｨ 03ｨｪ06 04ｨ 0607080201020507ｨｪ02 ｨｪｨ 00ｨ 08ｨｬｨ ｨｺ06050600ｨｨ ﾂｨｪｨｨｨｰ02 ｨｨｨｬ 020002ｨｺｨｰｨｨ 0902080607ｨｰｨｪ06 02 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02ｨｰ06 ｨｪｨ 080503 09 08ｨ 0405ｨｨ ﾂｨｪｨｨ ｨｰｨｲｨｺｨ ｨｪｨｨ (ｨ ｨｨｨｬ02ｨｪｨｪ06 09ｨｲ01060902, ｨ ｨｲｨ 0802ｨｺ, 09ｨｲ080202). 10 06ｨｲｨｦ ｨｺｨ ｨｰ06 080503-I ｨｨｨｬｨ ｨｰ 0201ｨｨｨｪ ｨｨ 09ｨｲｨｴ ｨｬ0201ｨ ｨｪｨｨ04ｨｲｨｬ ｨｪｨ 0102ｨｦ09ｨｰ09ｨｨ02, ｨｰ0201ｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ 0902 06ｨｰ01ｨ 09ｨ ｨｰ ｨｪｨ ｨｺ05ｨ 09ｨ ｨｬ0201ｨｨｨｺｨ ｨｬ02ｨｰｨｨ ｨｺｨ ｨｰ06 02070506. 00ｨｲ070802ｨｺｨｨ ｨｰ0609ｨ 09ｨ ｨｪｨ 05ｨｨ0202 09ｨ 03ｨｪｨｨ 08ｨ 0405ｨｨ ﾂｨｨ07 09 ｨ 00ｨｨｨｪｨｨｨｰ02ｨｰｨ ｨｪｨ 0909ｨｲ080409ｨ ｨｪ02 ｨｺｨｲｨｬ ｨｰｨｲｨｺｨ ｨｪｨｪｨｨ07 080503 ｨｨ ｨｨｨｪ01ｨｨ09ｨｨ01ｨｮｨ 05ｨｪｨｨｨｰ02 00ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨ ﾂｨｪｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｪｨ 06ｨｰ010205ｨｪｨｨｨｰ02 07080207ｨ 08ｨ ｨｰｨｨ, ｨｺ0602ｨｰ06 ｨｬ060302 01ｨ 02 0708ｨｨ ﾂｨｨｨｪｨ 04ｨ ｨｨ0408ｨ 0402ｨｪｨｨ 08ｨ 0405ｨｨｨｺｨｨ 09 ｨｰｨｲｨｺｨ ｨｪｨｪｨｨｨｰ02 ｨｨｨｬ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨ ｨｨ 060906ｨ 02ｨｪ0609ｨｰｨｨ 09 ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ. 000902 07ｨ ｨｺ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪoｨｰ06 04ｨｪｨ ﾂ02ｨｪｨｨ02 ｨｪｨ ｨｰｨ ｨｺｨｨ09ｨ 08ｨ 0405ｨｨ- ﾂｨｨ07 ｨｪｨｨｨｺ0600ｨ ｨｪ02 02 ｨ ｨｨ0506 0106ｨｺｨ 04ｨ ｨｪ06. 0009ｨｲｨｴｨｪ0609ｨｰ ｨｬ060302 01ｨ 0902 0708ｨｨ02ｨｬ02, ﾂ02 0909ｨｨ ﾂｨｺｨｨ ｨｪｨ 05ｨｨ ﾂｨｪｨｨ 090200ｨ 080503-I 09ｨ 0201ｨｪｨ ｨｺ0906 020002ｨｺｨｰｨｨ09ｨｪｨｨ 04ｨ 0706ｨｪｨｨ03ｨ 09ｨ ｨｪ02 ｨｪｨ ｨ 08ｨｰ0208ｨｨｨ 05ｨｪ06ｨｰ06 ｨｪｨ 050700ｨ ｨｪ02 (0801). 05ｨ ｨｰ0609ｨ ｨｨ04ｨ 0608ｨｲｨｰ ｨｨ 010604ｨ ｨｰｨ ｨｪｨ 080503-I ｨｰ0807ｨ 09ｨ 01ｨ 0902 0609ｨｪ0609ｨ 09ｨ ｨｪｨ 080204ｨｮ05ｨｰｨ ｨｰｨｨｨｰ02 06ｨｰ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨｨｰ02 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07, 09 ｨｺ06ｨｨｨｰ06 02 ｨｮ09ｨｰｨ ｨｪ060902ｨｪｨ 07060504ｨ ｨｰｨ 06ｨｰ ｨｰ0701ｨｪ06ｨｰ06 0708ｨｨ05060302ｨｪｨｨ02. 030002ｨｺｨｰｨｨ ｨｪｨ 080503-I 0902ｨｬ0601ｨｨｨｪｨ ｨｬｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ ACE-I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 06ｨ ｨｴ06ｨｰ06 070208ｨｨ000208ｨｪ06 09ｨｲ01060906 09ｨｲ070806ｨｰｨｨ090502ｨｪｨｨ02 (030505) ｨｨ 070609ｨｨ03ｨ 09ｨ ｨｰ ｨｪｨ ｨｰ08ｨｨｨｮ080204ｨ ｨｰｨ, ｨｪ06 ｨｪ02 070806ｨｬ02ｨｪ07ｨｰ 09ｨｲｨｴ0209ｨｰ0902ｨｪ06 09ｨｲ080102 ﾂｨｪｨ ｨｰｨ ﾂ0209ｨｰ06ｨｰｨ.1-4 060204ｨｨ 0102ｨｦ09ｨｰ09ｨｨ07 09ｨ 0909ｨｲ0804ｨ ｨｪｨｨ 09 0506ｨｺｨ 05ｨｪ06ｨｰ06 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02 ｨｪｨ 080503 ｨｨ 06ｨ 08ｨ 04ｨｮ09ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 09 09070202ｨｨ00ｨｨ ﾂｨｪｨｨ 0708ｨｨ020205ｨｪｨｨ 060800ｨ ｨｪｨｨ ｨｺｨ ｨｰ06 09ｨｲ010609ｨ ｨｰｨ 09ｨｰ02ｨｪｨ. 0308ｨｨ 05ｨｨ02ｨ 09 ｨｪ0608ｨｬｨ 05ｨｪ06 0801 ｨｨ 0708ｨｨ 01ｨｨ070208ｨｰ06ｨｪｨｨ02ｨｨ ｨ 0204 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501 ACE-I ｨｪ02 0905ｨｨ0707ｨｰ 09ｨｲｨｴ0209ｨｰ0902ｨｪ06 09ｨｲ0801ｨｮ 09ｨｲ080102 ﾂｨｪｨｨ07 0102ｨ ｨｨｨｰ ｨｨ 07ｨｮ05ｨｬ06-ｨｺｨ 07ｨｨ050708ｨｪ06ｨｰ06 ｨｪｨ 050700ｨ ｨｪ02. 05ｨ 08ｨ 0405ｨｨｨｺｨ 06ｨｰ 0108ｨｮ00ｨｨ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｨ, ｨｰ02 ｨｪ02 07080201ｨｨ0409ｨｨｨｺ09ｨ ｨｰ 0802000502ｨｺ09ｨｪｨ ｨｰｨ 01ｨｨｨｺｨ 0801ｨｨ07, 0902080607ｨｰｨｪ06 070608ｨ 01ｨｨ 020002ｨｺｨｰ 09ｨｲ0801ｨｮ ｨ ｨ 08060802020207ｨｰ0608ｨｪｨ ｨｰｨ ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｪ0609ｨｰ, 09ｨ 00ｨｮ090609ｨ ｨｰｨ 09ｨｰｨｨｨｬｨｮ05ｨ 02ｨｨ07 ｨｨ/ｨｨ05ｨｨ ｨｪｨ ｨｬｨ 0502ｨｪ06 09ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ ｨｪ02 ｨｪｨ 09ｨｨｨｬｨ 07ｨｰｨｨｨｺｨｮ090609ｨ ｨｰｨ ｨｪ020809ｨｪｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰ. 0102 07060905ｨｨ0709ｨ ｨｰ 070806ｨｬ02ｨｪｨｨｨｰ02 09 05 ﾁ 0706 090802ｨｬ02 ｨｪｨ 00ｨｨ04ｨｨ- ﾂ0209ｨｺ06 ｨｪｨ ｨｰ0609ｨ 0809ｨ ｨｪ02 ｨｨ05ｨｨ 070609ｨｰｨｮ08ｨ 05ｨｪｨｨｨｰ02 070806ｨｬ02ｨｪｨｨ. 11 ACE-I 09060107ｨｰ 0106 06ｨ 08ｨ ｨｰｨｪ06 08ｨ 0409ｨｨｨｰｨｨ02 ｨｪｨ 09ｨｲ080102 ﾂｨｪｨ ｨｰｨ 01ｨｨ070208ｨｰ080600ｨｨ07 0708ｨｨ 01ｨｨ070208ｨｰ06ｨｪｨｨ02ｨｨ 12 ｨｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 02ｨｪ0106ｨｰ0205ｨｪｨ ｨｰｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07 0708ｨｨ ｨｪ0608ｨｬ06ｨｰ06ｨｪｨｨ02ｨｨ 09 ｨｺ060806ｨｪｨ 08ｨｪｨ ｨ 06050209ｨｰ, 01ｨｨ070208ｨｰ06ｨｪｨｨ07, ｨｪ02ｨｨｨｪ09ｨｮ05ｨｨｨｪ0604ｨ 09ｨｨ09ｨｨｨｬ 04ｨ 01ｨ 0802ｨｪ 01ｨｨｨ ｨ 02ｨｰ ｨｨ 0501. 6,13-15 03060106ｨ 0802ｨｪｨｨ02ｨｰ06 09 02ｨｪ0106ｨｰ0205ｨｪｨ ｨｰｨ 00ｨｮｨｪｨｺ02ｨｨ07 02 0909ｨｲ0804ｨ ｨｪ06 09 06ｨｰ0905ｨ ｨ 09ｨ ｨｪ02 ｨｪｨ 09ｨ 0406ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺ02ｨｨ07ｨｰｨ ｨｨ ｨｨｨｪ01ｨｮ02ｨｨ08ｨ ｨｪ06 06ｨｰ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪｨ 070609ｨｨ0302ｨｪ06 070806ｨｨ0409060109ｨｰ0906 ｨｪｨ NO 06ｨｰ 02ｨｪ0106ｨｰ0205ｨ. 14,15 0308ｨｨ ｨ 0605ｨｪｨｨ 09ｨｲ09 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501 ACE-I 07080201ｨｨ0409ｨｨｨｺ09ｨ ｨｰ 0902ｨｪ0604ｨｪｨ ｨｨ ｨ 08ｨｰ0208ｨｨｨ 05ｨｪｨ 09ｨ 040601ｨｨ05ｨ ｨｰｨ 02ｨｨ07. 1-4 0002ｨｪ0604ｨｪｨ ｨｰｨ 09ｨ 040601ｨｨ05ｨ ｨｰｨ 02ｨｨ07 ｨｮ090205ｨｨ ﾂｨ 09ｨ 070208ｨｨ000208ｨｪｨ ｨｰｨ 0902ｨｪ0604ｨｪｨ 09ｨｬ0209ｨｰｨｨｨｬ0609ｨｰ (capacitance), ｨｪｨ ｨｬｨ 050709ｨ 010209ｨｪ060708020109ｨｲ0801ｨｪ06ｨｰ06 ｨｪｨ 050700ｨ ｨｪ02, ｨ 020506010806ｨ ｨｪ06ｨｰ06 ｨ 08ｨｰ0208ｨｨｨ 05ｨｪ06 ｨｪｨ 050700ｨ ｨｪ02, 07ｨｮ05ｨｬ06-ｨｺｨ 07ｨｨ050708ｨｪ06ｨｰ06 ｨｪｨ 050700ｨ ｨｪ02 ｨｨ 05020906ｨｺｨ ｨｬ0208ｨｪｨｨｨｰ02 06ｨ eｨｬｨｨ ｨｨ ｨｪｨ 050700ｨ ｨｪｨｨ07 ｨｪｨ 07ｨｲ05ｨｪ02ｨｪ02, ｨｺ0602ｨｰ06 090601ｨｨ 0106 ｨ ｨｲ080406 ｨｪｨ ｨｬｨ 050709ｨ ｨｪ02 ｨｪｨ ｨ 020506010806ｨ ｨｪｨｨ07 04ｨ 09ｨｰ06ｨｦ. 0808ｨｰ0208ｨｨｨ 05ｨｪｨｨ07ｨｰ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ060802ｨｪ 020002ｨｺｨｰ ｨｪｨ ｨｬｨ 050709ｨ 030505 ｨｨ 070609ｨｨ03ｨ 09ｨ 09ｨｲ080102 ﾂｨｪｨｨ07 0102ｨ ｨｨｨｰ. ACE-I 07060106ｨ 080709ｨ ｨｰ 09ｨｲ080102 ﾂｨｪｨ ｨｰｨ 080205ｨ ｨｺ09ｨ 02ｨｨ07 ｨｨ 08ｨ 04ｨｰ0203ｨｨｨｬ0609ｨｰ 0609ｨｰ0806, ｨ 01ｨｲ050006ｨｰ08ｨ ｨｦｨｪ06ｨｰ06 ｨｨｨｬ 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ ｨｬｨ 050709ｨ 01ｨｨ070208ｨｰ080600ｨｨ07ｨｰｨ ｨｨ 0801 0708ｨｨ 01ｨｨ070208ｨｰ06ｨｪｨｨ07. 3,4,6 0102090806010608ｨｬ06ｨｪｨ 05ｨｪｨｨ 020002ｨｺｨｰｨｨ 0808ｨ ｨｰｨｺ06ｨｰ08ｨ ｨｦｨｪ06ｨｰ06 0502 ﾂ02ｨｪｨｨ02 09 ACE-I 0902 09ｨｲ07ｨｲｨｰ09ｨｰ09ｨ 06ｨｰ 0706ｨｪｨｨ0302ｨｪｨｨ02 09 ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II ｨｨ ｨ 05010609ｨｰ020806ｨｪ, 070609ｨｨ0302ｨｪ06 06090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ 0802ｨｪｨｨｨｪ ｨｨ 070609ｨｨ0302ｨｪｨｨ ｨｪｨｨ09ｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ I. 16,17,18 06ｨｲｨｦ ｨｺｨ ｨｰ06 ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 07060905ｨｨ0709ｨ 070208ｨｨ000208ｨｪｨｨ07 ｨｨ 0202ｨｪｨｰ08ｨ 0502ｨｪ 09ｨｨｨｬ07ｨ ｨｰｨｨｨｺｨｮ090609 ｨｰ06ｨｪｨｮ09 ｨｨ 09ｨｰｨｨｨｬｨｮ05ｨｨ08ｨ 06090906ｨ 060301ｨ 09ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨｺｨ ｨｰ02010605ｨ ｨｬｨｨｨｪｨｨ 06ｨｰ ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ ｨｬ0201ｨｮ05ｨ, 7 080503- I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 0705ｨ 04ｨｬ02ｨｪｨｨｨｰ02 ｨｪｨｨ09ｨ ｨｪｨ ｨ 010802ｨｪｨ 05ｨｨｨｪｨ, ｨｪ0608ｨ 010802ｨｪｨ 05ｨｨｨｪｨ ｨｨ 09ｨ 040607080209ｨｨｨｪｨ. 02090902ｨｪ ｨｰ0609ｨ 070609ｨｨ0302ｨｪｨｨｨｰ02 ｨｪｨｨ09ｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ I ｨｬ0600ｨ ｨｰ 01ｨ 0106090201ｨ ｨｰ 0106 070609ｨｨ0302ｨｪｨ 07080601ｨｮｨｺ02ｨｨ07 ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ, 1-7 ｨｺ06ｨｦｨｰ06 0708ｨｨｨｰ0203ｨ 09ｨ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｪｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｨ 0106 09ｨｨｨｪｨｰ0204 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 0706 07ｨｲｨｰｨｨｨｴｨ, ｨｪ02ｨｬ0201ｨｨｨｨ08ｨ ｨｪｨｨ 06ｨｰ 080503 ( ﾂ080204 02ｨｪ04ｨｨｨｬｨ 01ｨｨｨｬｨ 04ｨ ). 19 0308ｨｨ 010806ｨｪｨｨ ﾂｨｪｨ 080503-ｨｨｨｪ01ｨｨｨ ｨｨ02ｨｨ07 ｨｨｨｬｨ ｨｰ02ｨｪ0102ｨｪｨｨ0207 04ｨ 0908ｨｲｨｴｨ ｨｪ02 ｨｪｨ ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II ｨｨ ｨ 05010609ｨｰ020806ｨｪ ｨｺｨｲｨｬ 09ｨｰ06ｨｦｨｪ0609ｨｰｨｨｨｰ02 07080201ｨｨ 04ｨ 0706 ﾂ09ｨ ｨｪ02 ｨｪｨ 0502 ﾂ02ｨｪｨｨ02ｨｰ06 090905020109ｨｰ09ｨｨ02 ｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨ 05ｨｰ0208ｨｪｨ ｨｰｨｨ09ｨｪｨｨ 07ｨｲｨｰｨｨｨｴｨ (0002ｨｪ06ｨｬ02ｨｪ ｨｪｨ 6 7ｨ 070009ｨｰ0906 ｱ ｨｪｨ ｨ 05010609ｨｰ020806ｨｪｨ ). 0502ｨｺ080202ｨｨ07ｨｰｨ ｨｪｨ ｨ 05010609ｨｰ020806ｨｪ 0902 07060101ｨｲ0803ｨ 06ｨｰ 0108ｨｮ00ｨｨ 09ｨｰ020806ｨｨ01060002ｨｪｨｪｨｨ 09ｨｰｨｨｨｬｨｮ05ｨｨ ｨｺｨ ｨｰ06 01ｨｨ- 6
13070208ｨｺｨ 05ｨｨ02ｨｬｨｨ07, 01ｨｨ070208ｨｬｨ 00ｨｪ0204ｨｨ02ｨｬｨｨ07 ｨｨ ｨ 010802ｨｪ06ｨｺ0608ｨｰｨｨｨｺ06ｨｰ08060702ｨｪ 010608ｨｬ06ｨｪ. 21,22 02ｨｰ 0108ｨｮ00ｨ 09ｨｰ08ｨ ｨｪｨ 080503-I 070609ｨｨ03ｨ 09ｨ ｨｰ ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨｺｨｨｨｪｨｨｨｪｨｨｨｰ02, 07080609ｨｰｨ 02ｨｨｨｺ05ｨｨｨｪｨ ｨｨ NO, ｨｺ0602ｨｰ06 06ｨｰ ﾂｨ 09ｨｰｨｨ ｨｬ060302 01ｨ 06ｨ 0709ｨｪｨｨ ｨｰ0201ｨｪｨｨｨｰ02 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｪｨｨ, ｨ ｨｪｨｰｨｨｨｰ0806ｨｬｨ 06ｨｰｨｨ ﾂｨｪｨｨ ｨｨ ｨ ｨｪｨｰｨｨ07080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪｨｨ 020002ｨｺｨｰｨｨ. 08ｨｪｨｰｨｨ07080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪｨｨ 020002ｨｺｨｰｨｨ 080503-I 0708ｨｨｨｰ0203ｨ 09ｨ ｨｰ ｨｨ ｨ ｨｪｨｰｨｨ07080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪｨｨ 020002ｨｺｨｰｨｨ (ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 01ｨｨ070208ｨｰ080600ｨｨ07ｨｰｨ ｨｪｨ 09ｨｲ01060902ｨｰ02, 09ｨｲ080202ｨｰ06 ｨｨ 07080605ｨｨ000208ｨ 02ｨｨ07ｨｰｨ ｨｪｨ 02ｨｺ09ｨｰ08ｨ 020205ｨｮ05ｨ 08ｨｪｨｨ07 ｨｬｨ ｨｰ08ｨｨｨｺ09) ｨｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｰ ｨｺｨ ｨｬ0208ｨｪ06ｨｰ06 0802ｨｬ06010205ｨｨ08ｨ ｨｪ02 09050201 ｨｬｨｨ06ｨｺｨ 080102ｨｪ ｨｨｨｪ00ｨ 08ｨｺｨｰ. 0602 09060107ｨｰ 0106 06ｨ 08ｨ ｨｰｨｪ06 08ｨ 0409ｨｨｨｰｨｨ02 ｨｪｨ ｨｺｨ ｨｬ0208ｨｪ06ｨｰ06 0802ｨｬ06010205ｨｨ08ｨ ｨｪ02 ﾂ080204 ｨｪｨ ｨｬｨ 050709ｨ ｨｪ02 ｨｪｨ 0708020109ｨ 08ｨｨｨｰ0205ｨｪｨｨ07 ｨｨ ｨｪｨ 090802ｨｴｨｪｨｨ07 ｨｰ0609ｨ 08 ｨｪｨ ｨｺｨ ｨｬ0208ｨ ｨｰｨ, 0708020106ｨｰ0908ｨ ｨｰ0709ｨ ｨｪ02 ｨｪｨ 07080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II ｨｨ 09ｨｨｨｬ07ｨ ｨｰｨｨｨｺｨｮ090609ｨ ｨｰｨ ｨｪ020809ｨｪｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰ, ｨｨ ﾂ080204 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨｨｨｪ01ｨｮ02ｨｨ08ｨ ｨｪｨ ｨｰｨ 06ｨｰ ｨ 05010609ｨｰ020806ｨｪｨ 09ｨｲ080102 ﾂｨｪｨ 01ｨｨ070208ｨｰ080600ｨｨ07, ｨｨｨｪｨｰ020809ｨｰｨｨ02ｨｨｨ 05ｨｪｨ ｨｨ 070208ｨｨ09ｨ 09ｨｺｨｮ05ｨ 08ｨｪｨ 00ｨｨｨ 080604ｨ. 11,12 080503-I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 01ｨｨ070208ｨｰ080600ｨｨ07ｨｰｨ ｨｨ 07060106ｨ 080709ｨ ｨｰ 01ｨｨｨ 09ｨｰ0605ｨｪｨ ｨｰｨ 00ｨｮｨｪ02ｨｨ07 ｨｪｨ 01ｨｨ070208ｨｰ080600ｨｨ08ｨ 0506ｨｰ06 09ｨｲ080202. 080503-I 0708020106ｨｰ0908ｨ ｨｰ0709ｨ ｨｰ ｨｨ ｨ 070607ｨｰ0604ｨ ｨｰｨ ｨｪｨ ｨｺｨ 0801ｨｨ06ｨｬｨｨ0602ｨｨｨｰｨｨｨｰ02 0708ｨｨ 06ｨ 02ｨｬｨｪ06 06ｨ 0802ｨｬ02ｨｪ02ｨｪｨｨ 09ｨｲ0802ｨ. 09ｨｲｨ 0802 ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 080503-I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ ｨ ｨｲｨ 0802 ﾂｨｪ06ｨｰ06 09ｨｲ01060906 09ｨｲ070806ｨｰｨｨ090502ｨｪｨｨ02 ｨｨ ｨｮ090205ｨｨ ﾂｨ 09ｨ ｨｰ ｨ ｨｲｨ 0802 ﾂｨｪｨｨ07 ｨｺ08ｨｲ0906ｨｰ06ｨｺ, ｨｪｨ ｨｰ08ｨｨｨｮ080204ｨ ｨｰｨ ｨｨ 090601ｨｪｨ ｨｰｨ 02ｨｺ09ｨｺ080202ｨｨ07. 00ｨｲ070802ｨｺｨｨ ｨｰ0609ｨ 09ｨｺ06080609ｨｰｨｰｨ ｨｪｨ 000506ｨｬ0208ｨｮ05ｨｪｨ 00ｨｨ05ｨｰ08ｨ 02ｨｨ07 (050108) 0609ｨｰｨ 09ｨ ｨｪ02070806ｨｬ02ｨｪ02ｨｪｨ ｨｨ05ｨｨ 0907ｨ 01ｨ 0502ｨｺ06, ｨ 00ｨｨ05ｨｰ0802ｨｨ06ｨｪｨｪｨ ｨｰｨ 0008ｨ ｨｺ02ｨｨ07 ｨｪｨ ｨｬｨ 050709ｨ. 060609ｨ 0902 01ｨｲ0503ｨｨ ｨｪｨ 06ｨｰｨｪ0609ｨｨｨｰ0205ｨｪ06 070609ｨｨ05ｨｪｨｨ07 01ｨｨ05ｨ ｨｰｨｨ08ｨ ｨｴ 020002ｨｺｨｰ 09ｨｲ0801ｨｮ 070609ｨｰ000506ｨｬ0208ｨｮ05ｨｪｨｨｨｰ02 0200020802ｨｪｨｰｨｪｨｨ ｨ 08ｨｰ0208ｨｨ0605ｨｨ 09 0908ｨ 09ｨｪ02ｨｪｨｨ02 09 020002ｨｺｨｰｨ 09ｨｲ0801ｨｮ ｨ 00020802ｨｪｨｰｨｪｨｨｨｰ02 ｨ 08ｨｰ0208ｨｨ0605ｨｨ, ｨｺ0602ｨｰ06 090601ｨｨ 0106 ｨｪｨ ｨｬｨ 050709ｨ ｨｪ02 ｨｪｨ 000506ｨｬ0208ｨｮ05ｨｪ06ｨｰ06 01ｨｨ01080609ｨｰｨ ｨｰｨｨ ﾂｨｪ06 ｨｪｨ 050700ｨ ｨｪ02 ｨｨ 050108. 25 01ｨ ｨｰ08ｨｨｨｮ080204ｨ ｨｰｨ 02 0905020109ｨｰ09ｨｨ02 06ｨｰ 07060106ｨ 0802ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ 0102ｨｬ0601ｨｨｨｪｨ ｨｬｨｨｨｺｨ, 0706ｨｪｨｨ0302ｨｪ06 06090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ ｨ 05010609ｨｰ020806ｨｪ ｨｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ, ｨｺ06ｨｨｨｰ06 06ｨｺｨ 0409ｨ ｨｰ 01ｨｨ0802ｨｺｨｰｨｪｨｨ 020002ｨｺｨｰｨｨ 09ｨｲ0801ｨｮ ｨｰｨｮｨ ｨｮ05ｨｨｨｰ02 ｨｨ ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02 ｨｪｨ 01ｨｨ0802ｨｺｨｰｨｪｨｨｨｰ02 ｨ ｨｲｨ 0802 ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II. A05E-I 0708020106ｨｰ0908ｨ ｨｰ0709ｨ ｨｰ 07080600080209ｨｨ07ｨｰｨ ｨｪｨ ｨｬｨｨｨｺ0806ｨ 05ｨ ｨｮｨｬｨｨｨｪｨｮ08ｨｨ07ｨｰｨ 0106 ｨｨ04070902ｨｪｨ 070806ｨｰ02ｨｨｨｪｨｮ08ｨｨ07, 26 04ｨ ｨ ｨ 0907ｨｰ 07080600080209ｨｨ07ｨｰｨ ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 08ｨ 0405ｨｨ ﾂｨｪｨｨ ｨｪ0201ｨｨｨ ｨ 02ｨｰｨｪｨｨ ｨｪ0200080607ｨ ｨｰｨｨｨｨ 27 ｨｨ 0708020106ｨｰ0908ｨ ｨｰ0709ｨ ｨｰ ｨｨ 04ｨ ｨ ｨ 0907ｨｰ 07080600080209ｨｨ07ｨｰｨ ｨｪｨ ｨｪ0200080607ｨ ｨｰｨｨ07ｨｰｨ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 ｨｨｨｪ09ｨｮ05ｨｨｨｪ0604ｨ 09ｨｨ09ｨｨｨｬ 04ｨ 01ｨ 0802ｨｪ 01ｨｨｨ ｨ 02ｨｰ. 28 0208ｨｮ00ｨｨ 020002ｨｺｨｰｨｨ 040805 ｨｨ0008ｨ 02 09ｨ 03ｨｪｨ 08060507 09 07ｨ ｨｰ060002ｨｪ0204ｨ ｨｰｨ ｨｨ 07080600080209ｨｨ07ｨｰｨ ｨｪｨ ｨ ｨｰ02080609ｨｺ0502080604ｨ ｨｰｨ. 6 0308ｨｨ 03ｨｨ0906ｨｰｨｨｨｪ09ｨｺｨｨ ｨｬ06010205ｨｨ 080503-I ｨｬ0600ｨ ｨｰ 01ｨ 04ｨ ｨ ｨ 0907ｨｰ 08ｨ 0409ｨｨｨｰｨｨ02ｨｰ06 ｨｪｨ ｨ ｨｰ02080609ｨｺ0502080604ｨ ｨｰｨ. 29,30 060204ｨｨ ｨ ｨｪｨｰｨｨｨ ｨｰ0208060002ｨｪｨｪｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｬ0600ｨ ｨｰ 01ｨ ｨ ｨｲ01ｨ ｨｰ 06ｨ 0709ｨｪ02ｨｪｨｨ 09 ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｴ06ｨｰ06 0102ｨｦ09ｨｰ09ｨｨ02 09ｨｲ0801ｨｮ 06ｨ 08ｨ 04ｨｮ09ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II, 0706ｨｰ02ｨｪ02ｨｨ08ｨ ｨｪ02ｨｰ06 ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪｨ ｨｨ 070609ｨｨ0302ｨｪ06 06090906ｨ 060301ｨ 09ｨ ｨｪ02 ｨｪｨ NO, 09060102ｨｴｨｨ 0106 ｨｪｨ ｨｬｨ 0502ｨｪｨ ｨｬｨｨ0008ｨ 02ｨｨ07 ｨｨ 07080605ｨｨ000208ｨ 02ｨｨ07 ｨｪｨ 09ｨｲ010609ｨｨ 0005ｨ 01ｨｺ06ｨｬｨｮ09ｨｺｨｮ05ｨｪｨｨ ｨｺ0502ｨｰｨｺｨｨ, ｨｪｨ ｨｬｨ 0502ｨｪ06 ｨｪｨ ｨｰ08ｨｮ0709ｨ ｨｪ02 ｨｨ ｨ ｨｺｨｰｨｨ09ｨｨ08ｨ ｨｪ02 ｨｪｨ 09ｨｲ0407ｨ 05ｨｨｨｰ0205ｨｪｨｨ ｨｺ0502ｨｰｨｺｨｨ, ｨｪｨ ｨｬｨ 0502ｨｪ 06ｨｺ09ｨｨ01ｨ ｨｰｨｨ0902ｨｪ 09ｨｰ080209 ｨｨ 07060106ｨ 0802ｨｪｨ 02ｨｪ0106ｨｰ0205ｨｪｨ 00ｨｮｨｪｨｺ02ｨｨ07. 030806ｨｮ ﾂ09ｨ ｨｪｨｨ07ｨｰｨ SAVE 31 (Survival And Ventricular Enlargement) ｨｨ SOLVD 32 (Studies Of Left Ventricular Dysfunction), ｨｺｨ ｨｺｨｰ06 ｨｨ 00060507ｨｬ ｨｬ02ｨｰｨ ｨ ｨｪｨ 05ｨｨ04 ｨｪｨ ｨｺ05ｨｨｨｪｨｨ ﾂｨｪｨｨ 070806ｨｮ ﾂ09ｨ ｨｪｨｨ07 33 0706ｨｺｨ 04ｨ 01ｨ, ﾂ02 080503-I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 09 20-25% 08ｨｨ09ｨｺｨ 06ｨｰ ｨｪ0209ｨｰｨ ｨ ｨｨ05ｨｪｨ ｨ ｨｪ00ｨｨｨｪｨ ｨｨ 070609ｨｰ060802ｨｪ ｨｬｨｨ06ｨｺｨ 080102ｨｪ ｨｨｨｪ00ｨ 08ｨｺｨｰ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 05020906ｨｺｨ ｨｬ0208ｨｪｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07 ｨｨ05ｨｨ 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501. 030806ｨｮ ﾂ09ｨ ｨｪ02ｨｰ06 HOPE 34 0102ｨｬ06ｨｪ09ｨｰ08ｨｨ08ｨ, ﾂ02 Ramipril ｨｪｨ ｨｬｨ 050709ｨ ｨ 06050209ｨｰｨｪ0609ｨｰｨｰｨ ｨｨ 09ｨｬｨｲ08ｨｰｨｪ0609ｨｰｨｰｨ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 070609ｨｨ0302ｨｪ 08ｨｨ09ｨｺ 06ｨｰ ｨ ｨｰ020806ｨｰ0806ｨｬｨ 06ｨｰｨｨ ﾂｨｪｨｨ 09ｨｲ080102 ﾂｨｪ06-09ｨｲ010609ｨｨ ｨｨｨｪ02ｨｨ0102ｨｪｨｰｨｨ. SECURE (the study to evaluate carotid ultrasound changes in patients treated with rami pril and vitamin E),070601070806ｨｮ ﾂ09ｨ ｨｪ02 ｨｪｨ HOPE, 0706ｨｺｨ 04ｨ, ﾂ02 01ｨｲ050006ｨｰ08ｨ ｨｦｨｪ06ｨｰ06 0502 ﾂ02ｨｪｨｨ02 09 080503-I 04ｨ ｨ ｨ 0907 07080600080209ｨｨ07ｨｰｨ ｨｪｨ ｨｺｨ 0806ｨｰｨｨ01ｨｪｨ ｨｰｨ ｨ ｨｰ02080609ｨｺ050902080604ｨ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09ｨｲ09 09ｨｲ010609ｨ ｨ 06050209ｨｰ ｨｨ05ｨｨ 01ｨｨｨ ｨ 02ｨｰ, ｨｪ06 ｨ 0204 09ｨｲ080102 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ ｨｨ 05020906ｨｺｨ ｨｬ0208ｨｪｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07. 35 030002ｨｺｨｰｨｨ 09ｨｲ0801ｨｮ 00ｨｨｨ 08ｨｨｨｪ0605ｨｨｨｰｨｨ ﾂｨｪｨｨ07 ｨ ｨ 05ｨ ｨｪ09 080503-I ｨｬ0601ｨｮ05ｨｨ08ｨ ｨｰ ｨｨ 09ｨｲ010609ｨｨ07 00ｨｨｨ 08ｨｨｨｪ0605ｨｨｨｰｨｨ ﾂ02ｨｪ ｨ ｨ 05ｨ ｨｪ09 ﾂ080204 ｨｪｨ ｨｬｨ 050709ｨ ｨｪ02 ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II, ｨｬ06ｨｴ02ｨｪ 09ｨｰｨｨｨｬｨｮ05 04ｨ 09ｨｨｨｪｨｰ0204ｨ ｨｪｨ PAI-1 (ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608 ｨｪｨ 0705ｨ 04ｨｬｨｨｨｪ060002ｨｪ0609ｨｨ07 ｨ ｨｺｨｰｨｨ09ｨ ｨｰ0608 ｨｰｨｨ07 1) ｨｨ ﾂ080204 070609ｨｨ03ｨ 09ｨ ｨｪ02 ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ0609ｨｨｨｰ02 ｨｪｨｨ09ｨ - ｨｬ06ｨｴ02ｨｪ 09ｨｰｨｨｨｬｨｮ05 04ｨ ｨｰｨｲｨｺｨ ｨｪｨｪｨｨ07 ｨ ｨｺｨｰｨｨ09ｨ ｨｰ0608 ｨｪｨ 0705ｨ 04ｨｬｨｨｨｪ060002ｨｪｨ. 36 0306 ｨｰｨ ｨｺｨｲ09 ｨｪｨ ﾂｨｨｨｪ 080503-I ｨｪｨ ｨｬｨ 050709ｨ ｨｰ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨｨｰ02 ｨｪｨ PAI- 1 ｨｨ ｨｬ0605ｨ 08ｨｪ06ｨｰ06 09ｨｲ06ｨｰｨｪ060302ｨｪｨｨ02 ｨｪｨ PAI-1 ｨｺｨｲｨｬ ｨｰｨｲｨｺｨ ｨｪｨｪｨｨ07 ｨ ｨｺｨｰｨｨ09ｨ ｨｰ0608 ｨｪｨ 0705ｨ 04ｨｬｨｨｨｪ060002ｨｪｨ. 080503-I 070806ｨｰｨｨ09060102ｨｦ09ｨｰ09ｨ ｨｰ ｨｪｨ ｨｰ0806ｨｬｨ 0602ｨｨｨｰｨｪｨ ｨｰｨ ｨ 00080200ｨ 02ｨｨ07, ｨｨｨｪ01ｨｮ02ｨｨ08ｨ ｨｪｨ 06ｨｰ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II, ｨｰｨｲｨｦ ｨｺｨ ｨｰ06 ｨｰ02 070609ｨｨ03ｨ 09ｨ ｨｰ 070806ｨｨ0409060109ｨｰ0906ｨｰ06 ｨｪｨ NO ｨｨ 07080609ｨｰｨ 02ｨｨｨｺ05ｨｨｨｪ. 05ｨｰ08ｨ ｨｪｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ 080503-I 0902 0706ｨｪｨ 0907ｨｰ 0106ｨ 0802 06ｨｰ 07060902 ﾂ02ｨｰ06 07ｨ 02ｨｨ02ｨｪｨｰｨｨ. 00ｨｲ070802ｨｺｨｨ ｨｰ0609ｨ ｨｬ060302 01ｨ ｨｪｨ 09ｨｰｨｲ0707ｨｰ ｨｪ07ｨｺ06ｨｨ 09ｨｰ08ｨ ｨｪｨｨ ﾂｨｪｨｨ 0802ｨ ｨｺ02ｨｨｨｨ. 1,2,37 09ｨｨ0706ｨｰ06ｨｪｨｨ07. 00060302 01ｨ 0902 07060709ｨｨ 09ｨｨｨｬ07ｨｰ06ｨｬｨ ｨｰｨｨ ﾂｨｪｨ 01ｨｨ0706ｨｰ06ｨｪｨｨ07 070608ｨ 01ｨｨ 06ｨｰ0905ｨ ｨ 09ｨ ｨｪ02 ｨｪｨ ｨｬ0201ｨｨｨｨ08ｨ ｨｪｨｨ07 06ｨｰ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II 09ｨ 0406ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺｨｰ060802ｨｪ ｨｰ06ｨｪｨｮ09, 060906ｨ 02ｨｪ06 09050201 07ｨｲ0809ｨ ｨｰｨ 010604ｨ ｨｪｨ ACE-I, 0706-09070202ｨｨｨ 05ｨｪ06 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 09ｨｨ0906ｨｺｨ 0705ｨ 04ｨｬ02ｨｪｨ 0802ｨｪｨｨｨｪ0609ｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰ (ｨｪｨ 0708ｨｨｨｬ0208 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09ｨｲ09 0906050209ｨｨ 010200ｨｨ02ｨｨｨｰ 070608ｨ 01ｨｨ 09ｨｨ0906ｨｺｨｨ 01ｨｨｨｮ0802ｨｰｨｨ ﾂｨｪｨｨ 010604ｨｨ ｨｨ05ｨｨ 09ｨｲ09 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501). 05ｨｮ01ｨ ｨｺｨ 0305ｨｨ02ｨ 0902 07090709ｨ 0708ｨｨ 5-10% 06ｨｰ 07ｨ 02ｨｨ02ｨｪｨｰｨｨｨｰ02 ｨｨ ｨｪ02 09ｨｨｨｪｨ 00ｨｨ 02 050209ｨｪ06 01ｨ ｨ ｨｲ0102 08ｨ 0405ｨｨ ﾂ02ｨｪｨ 06ｨｰ ｨｺｨ 0305ｨｨ02ｨ ｨｰｨ 09 080204ｨｮ05ｨｰｨ ｨｰ ｨｪｨ ｨ 020506010806ｨ 02ｨｪ 04ｨ 09ｨｰ06ｨｦ ｨｨ05ｨｨ 09ｨｲ07ｨｲｨｰ09ｨｰ09ｨ 03ｨｨ 08020907ｨｨ08ｨ ｨｰ0608ｨｪｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07. 41 03ｨｰｨｨ06050600ｨｨ07ｨｰｨ 02 ｨｪ02ｨｨ04090209ｨｰｨｪｨ, ｨｪ06 ｨｬ060302 01ｨ 02 0909ｨｲ0804ｨ ｨｪｨ 09 070609ｨｨ0302ｨｪｨｨｨｰ02 ｨｪｨｨ09ｨ ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ ｨｨ05ｨｨ 09ｨｮｨ 09ｨｰｨ 02ｨｨ07 P 09 ｨ 0205ｨｨｨｰ02 010806ｨ 060902. 08ｨ 0305ｨｨ02ｨ ｨｰｨ ｨｪ02 02 04ｨ 09ｨｨ09ｨｨｨｬｨ 06ｨｰ 010604ｨ ｨｰｨ, 090802ｨｴｨ 0902 0706- ﾂ0209ｨｰ06 0708ｨｨ 0302ｨｪｨｨ ｨｨ 09080201 ｨ 04ｨｨｨ ｨｰ09ｨｺｨｨｨｰ02 070607ｨｮ05ｨ 02ｨｨｨｨ, 06ｨ ｨｨｨｺｨｪ060902ｨｪ06 0902 07080607090709ｨ 06ｨｰ 0201ｨｪｨ 090201ｨｬｨｨ02ｨ 0106 ｨｪ07ｨｺ0605ｨｺ06 ｨｬ02090202ｨ 09050201 04ｨ 0706 ﾂ09ｨ ｨｪ02 ｨｪｨ 0502 ﾂ02ｨｪｨｨ02ｨｰ06 ｨｨ 0706ｨｪ07ｨｺ0600ｨ ｨｪｨ 05ｨ 00ｨ 070802ｨｺｨｲ0909ｨ ｨｪ02ｨｰ06 ｨｬｨｮ, 09ｨｲ070802ｨｺｨｨ ﾂ02 ｨｪ07ｨｺ06ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ ｨｬ0600ｨ ｨｰ 01ｨ 0706ｨｪ0209ｨ ｨｰ 070609ｨｰ0608ｨｪ06 0708ｨｨ05060302ｨｪｨｨ02 ｨｪｨ 080503-ｨｨｨｪ01ｨｨｨ ｨｨｨｰ0608 09050201 090906ｨ 060102ｨｪ 06ｨｰ 7
13ｨｬ0201ｨｨｨｺｨ ｨｬ02ｨｪｨｰｨ ｨｨｨｪｨｰ020809ｨ 05. 05050201 ｨｺｨ ｨｰ06 090201ｨｪｨｲ03 ｨ ｨｲ0102 070802ｨｺｨｲ09ｨｪｨ ｨｰｨ ｨｰ0208ｨ 07ｨｨ07ｨｰｨ, ｨｺｨ 0305ｨｨ02ｨ ｨｰｨ 06ｨ ｨｨｨｺｨｪ060902ｨｪ06 ｨｨ04 ﾂ020409ｨ 04ｨ ｨｪ02 07060902 ﾂ02 06ｨｰ 3-5 01ｨｪｨｨ. 00020301ｨｮ 06ｨｰ010205ｨｪｨｨｨｰ02 080503- I ｨｪ07ｨｬｨ 08ｨ 0405ｨｨｨｺｨ 09 ｨｰ02ｨｪ0102ｨｪ02ｨｨ07ｨｰｨ 01ｨ 0708ｨｨ ﾂｨｨｨｪ0709ｨ ｨｰ ｨｺｨ 0305ｨｨ02ｨ. 09ｨｨ070208ｨｺｨ 05ｨｨ02ｨｬｨｨ07 070608ｨ 01ｨｨ ｨｪｨ ｨｬｨ 0502ｨｪｨ 0902ｨｺ080202ｨｨ07 ｨｪｨ ｨ 05010609ｨｰ020806ｨｪ 0902 090802ｨｴｨ 080701ｨｺ06 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 ｨｪ0608ｨｬｨ 05ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ 00ｨｮｨｪｨｺ02ｨｨ07, ｨｪ06 02 06ｨｰｨｪ0609ｨｨｨｰ0205ｨｪ06 ﾂ0209ｨｰｨ 0708ｨｨ 09ｨｲ0408ｨ 09ｨｰｨｪｨｨ ｨｨ 0708ｨｨ ｨ 0605ｨｪｨｨ 09ｨｲ09 04ｨ 09ｨｰ06ｨｦｨｪｨ 0501. 0306- ﾂ0209ｨｰ06 0902 07090709ｨ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 ｨ ｨｲｨ 0802 ﾂｨｪ06 ｨｮ0908020301ｨ ｨｪ02, 01ｨｨｨ ｨ 02ｨｰｨｨ02ｨｨ, 070605ｨｮ ﾂｨ 09ｨ ｨｴｨｨ 08 + ｨｨ05ｨｨ ｨｺｨ 05ｨｨｨｦ-09ｨｲ0108ｨ ｨｪ0709ｨ ｨｴｨｨ 01ｨｨｨｮ0802ｨｰｨｨ02ｨｨ, 010207ｨ 08ｨｨｨｪ ｨｨ05ｨｨ ｨｪ0209ｨｰ020806ｨｨ01ｨｪｨｨ 070806ｨｰｨｨ090609ｨｲ0407ｨ 05ｨｨｨｰ0205ｨｪｨｨ 0908020109ｨｰ09ｨ (0105030005). 42,43 0209ｨｰ08ｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ. 080503-I ｨｬ0600ｨ ｨｰ 01ｨ 070609ｨｨ03ｨ ｨｰ ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨｮ0802ｨｦｨｪｨｨ07 ｨ 0406ｨｰ ｨｨ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪｨ. 0308ｨｨ 07060902 ﾂ02ｨｰ06 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 010601ｨ ｨｪｨ 07080601ｨｲ0503ｨｨｨｰ0205ｨｪ06 0502 ﾂ02ｨｪｨｨ02 ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪｨ o09ｨｰｨ 09ｨ ｨｰ 09ｨｰｨ ｨ ｨｨ05ｨｪｨｨ ｨｨ05ｨｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 0106 09ｨｰ06ｨｦｨｪ0609ｨｰｨｨｨｰ02 07080201ｨｨ 04ｨ 0706 ﾂ09ｨ ｨｪ02 ｨｪｨ 0502 ﾂ02ｨｪｨｨ02ｨｰ06. 0209ｨｰ08ｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ 0902 090802ｨｴｨ 0706- ﾂ0209ｨｰ06 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 010201ｨｨ0108ｨ ｨｰｨ 02ｨｨ07 090905020109ｨｰ09ｨｨ02 09ｨｨ0906ｨｺｨｨ 010604ｨｨ 01ｨｨｨｮ0802ｨｰｨｨ02ｨｨ, 01ｨｨ0706ｨｪｨ ｨｰ08ｨｨ02ｨｬｨｨ07, 0109ｨｮ09ｨｰ08ｨ ｨｪｨｪｨ 09ｨｰ02ｨｪ0604ｨ ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨｨｨｰ02 ｨ 08ｨｰ0208ｨｨｨｨ, 09ｨｰ02ｨｪ0604ｨ ｨｪｨ 0106ｨｬｨｨｨｪｨｨ08ｨ ｨｴｨ ｨｰｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨ 08ｨｰ0208ｨｨ07 ｨｨ05ｨｨ 0708ｨｨ 0201ｨｨｨｪ ｨ ｨｲｨ 0802ｨｺ ｨｨ 0708ｨｨ 080202ｨｨ07ｨｨ02ｨｪｨｰｨｨ ｨｪｨ ｨ ｨｲｨ 0802 ﾂ02ｨｪ ｨｰ08ｨ ｨｪ090705ｨ ｨｪｨｰｨ ｨｰ. 0308ｨｨ ｨｰ0204ｨｨ 06ｨ 09ｨｰ0607ｨｰ020509ｨｰ09ｨ 06090906ｨ 060301ｨ 09ｨ ｨｪ02ｨｰ06 ｨｪｨ 0802ｨｪｨｨｨｪ ｨｪｨ 08ｨ 09ｨｰ09ｨ ｨｨ 090601ｨｨ 0106 070609ｨｨ0302ｨｪｨｨ ｨｪｨｨ09ｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II, ｨｺ06ｨｦｨｰ06 07080201ｨｨ0409ｨｨｨｺ09ｨ ｨｨ04ｨ ｨｨ08ｨ ｨｰ0205ｨｪｨ ｨｺ06ｨｪ09ｨｰ08ｨｨｨｺ02ｨｨ07 ｨｪｨ 0200020802ｨｪｨｰｨｪｨｨｨｰ02 ｨ 08ｨｰ0208ｨｨ0605ｨｨ ｨｨ 0706ｨｬｨ 00ｨ 04ｨ 07060101ｨｲ0803ｨ ｨｪ02ｨｰ06 ｨｪｨ 09ｨｺ06080609ｨｰｨｰｨ ｨｪｨ 000506ｨｬ0208ｨｮ05ｨｪｨ 00ｨｨ05ｨｰ08ｨ 02ｨｨ07. 080503-I 0706ｨｪｨｨ03ｨ 09ｨ ｨｰ ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨ ｨｪ00ｨｨ06ｨｰ02ｨｪ04ｨｨｨｪ II, 07080201ｨｨ0409ｨｨｨｺ09ｨ ｨｰ 09ｨ 040601ｨｨ05ｨ ｨｰｨ 02ｨｨ07 ｨｪｨ 0200020802ｨｪｨｰｨｪｨｨｨｰ02 ｨ 08ｨｰ0208ｨｨ0605ｨｨ ｨｨ ｨｪｨ ｨｬｨ 050709ｨ ｨｰ 000506ｨｬ0208ｨｮ05ｨｪｨ ｨｰｨ 00ｨｨ05ｨｰ08ｨ 02ｨｨ07, 09 080204ｨｮ05ｨｰｨ ｨｰ ｨｪｨ ｨｺ0602ｨｰ06 ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪｨ ｨｪｨ 08ｨ 09ｨｰ09ｨ ｨｰ. 00ｨｲ070802ｨｺｨｨ ｨｰ0609ｨ 0708ｨｨ 0706 ﾂｨｰｨｨ 0909ｨｨ ﾂｨｺｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ ｨｪｨ 09ｨｰｨｲ0709ｨ 09ｨｲ0409ｨｰｨ ｨｪ06090709ｨ ｨｪ02 ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ 00ｨｮｨｪｨｺ02ｨｨ07 09050201 070802ｨｺｨｲ0909ｨ ｨｪ02 ｨｪｨ 080503-I. 44 030806ｨｰ02ｨｨｨｪｨｮ08ｨｨ07. 080503-I ｨｬ0600ｨ ｨｰ 01ｨ 07080201ｨｨ0409ｨｨｨｺｨ ｨｰ 070806ｨｰ02ｨｨｨｪｨｮ08ｨｨ07. 03080201030209ｨｰ09ｨ ｨｴｨ ｨｰｨ 070806ｨｰ02ｨｨｨｪｨｮ08ｨｨ07, 06ｨ ｨ ﾂ02, ｨｪ02 02 070806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ02 04ｨ 0502 ﾂ02ｨｪｨｨ02 09 080503-I, ｨｰｨｲｨｦ ｨｺｨ ｨｰ06 02 ｨｮ09ｨｰｨ ｨｪ060902ｨｪ06, ﾂ02 ｨｰ02 0708ｨｨｨｰ0203ｨ 09ｨ ｨｰ ｨｪ02000806070806ｨｰ02ｨｺｨｰｨｨ09ｨｪｨｨ 020002ｨｺｨｰｨｨ 0708ｨｨ ｨ ｨｲｨ 0802 ﾂｨｪｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07, 070806ｨｰｨｨ ﾂｨ ｨｴｨｨ 09 070806ｨｰ02ｨｨｨｪｨｮ08ｨｨ07 (ｨｪｨ 0708ｨｨｨｬ0208 01ｨｨｨ ｨ 02ｨｰｨｪｨ ｨｪ0200080607ｨ ｨｰｨｨ07). 08ｨｪ00ｨｨ06020102ｨｬｨｲｨｰ 02 080701ｨｲｨｺ, ｨｪ06 0706ｨｰ02ｨｪ02ｨｨｨ 05ｨｪ06 03ｨｨ0906ｨｰ0604ｨ 09ｨｰ08ｨ 03ｨ 09ｨ ｨｴ 09ｨｰ08ｨ ｨｪｨｨ ﾂ02ｨｪ 020002ｨｺｨｰ. 05ｨｨｨｬ07ｨｰ06ｨｬｨｨｨｰ02 09ｨ 08ｨｨ08ｨ ｨｰ 06ｨｰ 0502ｨｺｨｨ 00ｨ 09ｨｰ0806ｨｨｨｪｨｰ0209ｨｰｨｨｨｪｨ 05ｨｪｨｨ ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 (00ｨ 0102ｨｪ02, 07060908ｨｲｨｴｨ ｨｪ02, 01ｨｨｨ 08ｨｨ07, ｨｺ0605ｨｨｨｺｨ ) 0106 ｨｰ0203ｨｺｨ 01ｨｨ0907ｨｪ0207 090905020109ｨｰ09ｨｨ02 06ｨｰ06ｨｺ ｨｪｨ 05ｨ 08ｨｨｨｪｨｺ09ｨ ｨｨ 09ｨｬｨｲ08ｨｰ. 050802ｨｴｨ 0902 0706- ﾂ0209ｨｰ06 07080204 07ｨｲ0809ｨｨ07 ｨｬ02090202 06ｨｰ 0502 ﾂ02ｨｪｨｨ02ｨｰ06 ｨｨ 09080201 ﾂ0208ｨｪ06ｨｺ0603ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ. 0604 ﾂ020409ｨ 09 08ｨ ｨｬｨｺｨｨｨｰ02 ｨｪｨ ﾂｨ 09060902 09050201 0907ｨｨ08ｨ ｨｪ02 ｨｪｨ 080503-I. 41,45 000201ｨ ｨｪｨｨ04ｨｬｨｲｨｰ ｨｨ040005020301ｨ 09ｨｺ0506 ﾂ09ｨ ｨｪｨ ｨｰ08ｨｮ0709ｨ ｨｪ02 ｨｪｨ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ ｨｨ ｨｪ02000609ｨｨ07 ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰ 010204ｨ 0800ｨｨｨｪｨｨｨｪ ｨ 08ｨ 01ｨｨｨｺｨｨｨｪｨｨｨｪ ｨｨ ｨｨｨｪ01ｨｨｨ ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨｺ06ｨｬ070502ｨｬ02ｨｪｨｰ - 1 0209ｨｰ0208ｨ 04ｨｪｨｨ07 ｨｨｨｪｨ ｨｺｨｰｨｨ09ｨ ｨｰ0608. 060208ｨ ｨｰ060002ｨｪｨｪｨｨ 020002ｨｺｨｰｨｨ. 08ｨｺ06 ｨ ｨｲ01ｨ ｨｰ 0708ｨｨ05060302ｨｪｨｨ 0706 090802ｨｬ02 ｨｪｨ 09ｨｰ0608ｨｨ07 ｨｨ05ｨｨ ｨｰ0802ｨｰｨｨ07 ｨｰ08ｨｨｨｬ0209ｨｰｨｲ08 06ｨｰ ｨ 0802ｨｬ02ｨｪｨｪ0609ｨｰｨｰｨ, 080503-I ｨｬ0600ｨ ｨｰ 01ｨ 0708ｨｨ ﾂｨｨｨｪ07ｨｰ 0002ｨｰｨ 05ｨｪｨｨ ｨ ｨｪ06ｨｬｨ 05ｨｨｨｨ (ｨ ｨｨｨｬ02ｨｪｨｪ06 0605ｨｨ000601ｨｨ0108ｨ ｨｬｨｪｨｨ06ｨｪ, ｨ 020506010806ｨ ｨｪｨ 01ｨｨ07060705ｨ 04ｨｨ07, 04ｨ 01ｨｲ0803ｨ ｨｪ02 ｨｪｨ 0002ｨｰｨ 05ｨｪｨｨ07 08ｨ 04ｨｰ0203, ｨ ｨｲｨ 0802 ﾂｨｪｨ 01ｨｨ090002ｨｪ0204ｨｨ07, ｨｪ0206ｨｪｨ ｨｰｨ 05ｨｪｨ ｨ ｨｪｨｮ08ｨｨ07 ｨｨ ｨｪ0206ｨｪｨ ｨｰｨ 05ｨｪｨ 09ｨｬｨｲ08ｨｰ). 46 0208ｨｮ00ｨｨ 09ｨｰ08ｨ ｨｪｨｨ ﾂｨｪｨｨ 020002ｨｺｨｰｨｨ, ｨｪ020909ｨｲ0804ｨ ｨｪｨｨ 09 080503-I, 09ｨｺ0506 ﾂ09ｨ ｨｰ ｨ 0002ｨｮ04ｨｨ07 ｨｨ 0108ｨｮ00ｨｨ ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 09ｨｲ09 09ｨｺｨｮ09ｨ (060906ｨ 02ｨｪ06 0708ｨｨ 09ｨｲ0408ｨ 09ｨｰｨｪｨｨ), ｨｪ02ｨｮｨｰ08060702ｨｪｨｨ07 ｨｨ ｨｬｨ ｨｺｨｮ05ｨｨ07ｨ 07ｨｮ05060402ｨｪ 06ｨ 08ｨｨ09. 0102ｨｮｨｰ08060702ｨｪｨｨ07 0902 07090709ｨ 08ｨ 01ｨｺ06, 0706- ﾂ0209ｨｰ06 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 ｨ ｨｲｨ 0802 ﾂｨｪｨｨ 04ｨ ｨ 06050709ｨ ｨｪｨｨ07 ｨｨ ｨｺ0605ｨ 0002ｨｪ0604ｨｨ. 030806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ07 08ｨ 09060506ｨｰｨｪｨｨ 070806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ07 04ｨ 04ｨ 0706 ﾂ09ｨ ｨｪ02 ｨｪｨ 0502 ﾂ02ｨｪｨｨ02 09 080503-I 09ｨ ｨ ｨｪｨ ｨｬｨｪ0204ｨ 04ｨ ｨ ｨｪ00ｨｨ06ｨｪ02090806ｨｰｨｨ- ﾂ02ｨｪ 020102ｨｬ, ｨ 05020800ｨｨ07 ｨｨ 0109ｨｮ09ｨｰ08ｨ ｨｪｨｪｨ 09ｨｰ02ｨｪ0604ｨ ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨｨｨｰ02 ｨ 08ｨｰ0208ｨｨｨｨ. 00ｨｲ070802ｨｺｨｨ ﾂ02 080503-I ｨｪ02 09ｨ 070806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ 0708ｨｨ 0302ｨｪｨｨ 09 080207080601ｨｮｨｺｨｰｨｨ09ｨｪｨ 09ｨｲ0408ｨ 09ｨｰ, ｨｰ02 ｨｰ0807ｨ 09ｨ 01ｨ ｨ ｨｲ01ｨ ｨｰ 070802ｨｺｨｲ09ｨｪｨ ｨｰｨｨ 090201ｨｪｨ 00ｨ 0708ｨｨ 09ｨｲｨｬｨｪ02ｨｪｨｨ02 04ｨ ｨ 0802ｨｬ02ｨｪｨｪ0609ｨｰ ｨｨ05ｨｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ02ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨｰｨ ｨｺｨ 09ｨ. 4,46-48 01ｨｨ09ｨｺｨｨｨｰ02 09ｨｰ06ｨｦｨｪ0609ｨｰｨｨ ｨｪｨ 0801 (09ｨｨ09ｨｰ0605ｨｪ06 <90 mmhg) 0706 090802ｨｬ02 ｨｪｨ 0502 ﾂ02ｨｪｨｨ02 09 080503-I 09ｨ 0708ｨｨ02ｨｬ05ｨｨ09ｨｨ, ｨ ｨｺ06 07ｨ 02ｨｨ02ｨｪｨｰｨｲｨｰ 02 ｨ 09ｨｨｨｬ07ｨｰ06ｨｬｨ ｨｰｨｨ ﾂ02ｨｪ. 08ｨｺ06 ｨｺｨ 05ｨｨ07ｨｰ 0902 070609ｨｨ03ｨｨ >6,0 mmol/l ｨｨ05ｨｨ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪｨｲｨｰ ｨｪｨ 08ｨ 09ｨｰｨｪ02 09 >50% ｨｨ05ｨｨ ｨｪｨ 01 3 mg/dl (256 08mol/ L) 0708ｨｨ05060302ｨｪｨｨ02ｨｰ06 ｨｪｨ 080503-I ｨｰ0807ｨ 09ｨ 01ｨ ｨ ｨｲ0102 09070807ｨｪ06. 07ｨｬ020802ｨｪｨ ｨｰｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｪ02010609ｨｰｨ ｨｰｨｲ ﾂｨｪ0609ｨｰ (090208ｨｮｨｬ02ｨｪ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪ 3 mg/dl ｨｨ05ｨｨ 0106 256 08mol/L, 0502ｨｺｨ ｨｰｨ 01ｨｨ070208ｨｺｨ 05ｨｨ02ｨｬｨｨ07 (05 6,0 mmol/l) ｨｨ 06ｨｰｨｪ0609ｨｨｨｰ0205ｨｪ06 ｨｪｨｨ09ｨｺ06ｨｰ06 0801 (010608ｨｨ 09ｨｨ09ｨｰ0605ｨｪ06 ｨｪｨ 050700ｨ ｨｪ02 90 mmhg) ｨｪ02 09ｨ 070806ｨｰｨｨ09060706ｨｺｨ 04ｨ ｨｪｨｨ07 04ｨ 0502 ﾂ02ｨｪｨｨ02 09 080503-I, ｨｪ06 ｨｰ0208ｨ 07ｨｨ07ｨｰｨ ｨｰ0807ｨ 09ｨ 01ｨ 07080601ｨｲ0503ｨｨ 0708ｨｨ 09ｨｪｨｨｨｬｨ ｨｰ0205ｨｪ06 ｨｬ06ｨｪｨｨｨｰ0608ｨｨ08ｨ ｨｪ02 ｨｪｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ ｨｰｨ 00ｨｮｨｪｨｺ02ｨｨ07. 04ｨｨ09ｨｺｨｲｨｰ 06ｨｰ 01ｨｨ0706ｨｰ06ｨｪｨｨ07 ｨｨ ｨ ｨｲｨ 0802 ﾂｨｪｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07 ｨｪｨ 08ｨ 09ｨｰ09ｨ 0708ｨｨ 09ｨｨ0906ｨｺｨｨ 010604ｨｨ, 0708ｨｨ 09ｨｲ0408ｨ 09ｨｰｨｪｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ ｨｨ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09ｨｲ09 ｨｰ0203ｨｺｨ 0501, 0708ｨｨ ｨｰ0204ｨｨ, 0502ｨｺｨｮ09ｨ ｨｪｨｨ 09 09ｨｨ0906ｨｺｨｨ 010604ｨｨ 01ｨｨｨｮ0802ｨｰｨｨ02ｨｨ, 09 ｨ ｨｲｨ 0802 ﾂｨｪｨ 01ｨｨ0900ｨｮｨｪｨｺ02ｨｨ07 ｨｨ05ｨｨ 01ｨｨ0706ｨｪｨ ｨｰ08ｨｨ02ｨｬｨｨ07. 080503-I, ｨｺｨ ｨｺｨｰ06 ｨｨ 0108ｨｮ00ｨｨｨｰ02 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｨ, ｨｰ0807ｨ 09ｨ 01ｨ 0902 ｨｨ04ｨ 070009ｨ ｨｰ 0708ｨｨ 07ｨ 02ｨｨ02ｨｪｨｰｨｨ 09 01ｨｨｨｪｨ ｨｬｨｨ ﾂｨｪｨ 06ｨ 09ｨｰ08ｨｮｨｺ02ｨｨ07 ｨｪｨ ｨｨ04010601ｨｪｨｨ07 ｨｰ08ｨ ｨｺｨｰ ｨｪｨ 050709ｨ ｨｰｨ ｨｺｨ ｨｬ0208ｨ. 49 0902ｨｺｨ 0809ｨｰ0902ｨｪｨｨ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 08ｨｪｨｰｨｨｨ 02ｨｨ01ｨｪｨｨｨｰ02 0908020109ｨｰ09ｨ ｨｬ0600ｨ ｨｰ 01ｨ ｨｪｨ ｨｬｨ 0507ｨｰ ｨ ｨｨ06ｨｪｨ 05ｨｨ ﾂｨｪ0609ｨｰｨｰｨ ｨｪｨ 080503-I. 010209ｨｰ020806ｨｨ01ｨｪｨｨｨｰ02 070806ｨｰｨｨ090609ｨｲ0407ｨ 05ｨｨｨｰ0205ｨｪｨｨ 0908020109ｨｰ09ｨ ｨｬ0600ｨ ｨｰ 01ｨ ｨｪｨ ｨｬｨ 0507ｨｰ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ ｨｪｨ 080503-I. 08 + -09ｨｲ0108ｨ ｨｪ0709ｨ 03ｨｨｨｰ02 01ｨｨｨｮ0802ｨｰｨｨ02ｨｨ, ｨｺｨ 05ｨｨ0209ｨｨｨｰ02 0106ｨ ｨ 09ｨｺｨｨ ｨｨ05ｨｨ 04ｨ ｨｬ0209ｨｰｨｨｨｰ0205ｨｨｨｰ02 ｨｪｨ 0006ｨｰ09ｨ 0809ｨｺｨ ｨｰｨ 090605 09 09ｨｨ0906ｨｺ06 09ｨｲ01ｨｲ0803ｨ ｨｪｨｨ02 ｨｪｨ 08 + ｨｬ0600ｨ ｨｰ 01ｨ 06ｨ 0609ｨｰ0807ｨｰ 07080201ｨｨ0409ｨｨｨｺｨ ｨｪｨ ｨｰｨ 06ｨｰ 080503-I 01ｨｨ070208ｨｺｨ 05ｨｨ02ｨｬｨｨ07 ｨｨ 04ｨ ｨｰ0609ｨ ｨｰ0204ｨｨ ｨｺ06ｨｬｨ ｨｨｨｪｨ 02ｨｨｨｨ ｨｰ0807ｨ 09ｨ 01ｨ 0902 ｨｨ04ｨ 070009ｨ ｨｰ. 02ｨｰ 0108ｨｮ00ｨ 09ｨｰ08ｨ ｨｪｨ, 0708ｨｨ 09ｨｪｨｨｨｬｨ ｨｰ0205ｨｪ06 ｨｬ06ｨｪｨｨｨｰ0608ｨｨ08ｨ ｨｪ02, ｨｺ06ｨｬｨ ｨｨｨｪｨ 02ｨｨ07ｨｰｨ 06ｨｰ 080503-I ｨｨ Spironolacton ｨｬ060302 01ｨ ｨ ｨｲ0102 0706050204ｨｪｨ. 08ｨｺ06 ｨｪｨｨ09ｨ ｨｰｨ ｨｪｨ ｨｮ080207ｨｰｨ ｨｨ05ｨｨ ｨｺ0802ｨ ｨｰｨｨｨｪｨｨｨｪｨ ｨｪｨ 08ｨ 09ｨｰｨｪｨ ｨｰ 070802ｨｺｨ 0502ｨｪ06, ｨｰ0807ｨ 09ｨ 01ｨ 0902 06ｨ ｨｬｨｨ0905ｨｨ 070802ｨｺｨｲ0909ｨ ｨｪ02 ｨｪｨ 09ｨｲ07ｨｲｨｰ09ｨｰ09ｨ ｨｴｨｨ ｨｪ02000806ｨｰ06ｨｺ09ｨｨ ﾂｨｪｨｨ ｨｬ0201ｨｨｨｺｨ ｨｬ02ｨｪｨｰｨｨ (ｨｪｨ 0708. 0105030005, Cyclosporin). ACE-I ｨｬ0600ｨ ｨｰ 01ｨ 070609ｨｨ03ｨ ｨｰ 0705ｨ 04ｨｬ02ｨｪｨｨｨｰ02 ｨｪｨｨ09ｨ ｨｪｨ 01ｨｨ0006ｨｺ09ｨｨｨｪｨ ｨｨ 05ｨｨｨｰｨｨ07. 03ｨ 02ｨｨ02ｨｪｨｰｨｨｨｰ02, 0708ｨｨ02ｨｬｨ ｨｴｨｨ 01ｨｨｨｮ0802ｨｰｨｨ02ｨｨ, 09ｨ 060906ｨ 02ｨｪ06 ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｪｨｨ ｨｺｨｲｨｬ 09ｨ 040601ｨｨ05ｨ ｨｰｨ ｨｰ0608ｨｪｨｨｨｰ02 020002ｨｺｨｰｨｨ ｨｪｨ ACE-I. 050706080201 ｨｪ07ｨｺ06ｨｨ 8