130002ｨｰ060104 09ｨｨｨｪｨｰ0204ｨ ｨｨ ｨｰ0201ｨｪ06050600ｨｨ07 070806ｨｨ0409060109ｨｰ09ｨ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 0908020109ｨｰ09 08 0806050502ｨｺｨｰｨｨ09 ｨ 09ｨｰ06080609, 2012 02. 07. 080803ｨｨｨｪ0609ｨ, 03. 00. 05ｨ ｨｪｨ 080609ｨ, 08. 00. 09ｨ ｨｪ020609ｨ, 01. 08. 02ｨ 060806ｨｰ0609ｨ 0205020903010102050606 090602080609060508000606 09060302050200080905010409 09030808040506000301010409 03040303080408060200 (0209050204) 0802010208ｨ 05ｨｹｨｪ0602 000609ｨｮ01ｨ 0809ｨｰ0902ｨｪｨｪ0602 ｨ 06010302ｨｰｨｪ0602 ｨｮ ﾂ0802030102ｨｪｨｨ02 ｰ04060909ｨｨｨｦ09ｨｺｨｨｨｦ 06ｨｪｨｺ06050600ｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｪｨ ｨｮ ﾂｨｪ04ｨｦ 0202ｨｪｨｰ08 ｨｨｨｬ. 01. 01. 09050601ｨｨｨｪｨ 04080001 ｱ (08010907 04020100 ｨｨｨｬ. 01. 01. 09050601ｨｨｨｪｨ 04080001), 000609ｨｺ09ｨ, 04060909ｨｨ07 09ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ07 ｪ ｨｬｨｪ06000606ｨ 02ｨｴｨ 06ｨｴｨｨｨｦ ｨｬ02ｨｰ0601, 0706040906050706ｨｴｨｨｨｦ 00ｨ 08ｨ ｨｪｨｰｨｨ080609ｨ ｨｰｨｹ 0105ｨｨｨｰ0205ｨｹｨｪｨｮ06 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0609ｨｰｨｹ 05ｨｨ07060906ｨｬ. 00 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 07080609020102ｨｪｨｪ0401 ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 09 01ｨ ｨｪｨｪ06ｨｦ 06ｨ 05ｨ 09ｨｰｨｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ06, ﾂｨｰ06 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ060804 06ｨ 05ｨ 01ｨ 06ｨｰ 08ｨ 0405ｨｨ ﾂｨｪ04ｨｬｨｨ ｨｬ0201ｨ ｨｪｨｨ04ｨｬｨ ｨｬｨｨ 0102ｨｦ09ｨｰ09ｨｨ07, ｨｰｨ ｨｺｨｨｨｬｨｨ ｨｺｨ ｨｺ 04ｨ ｨｬ02ｨｴ02ｨｪｨｨ02 09060104 ｨｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｬｨ ｨｰ08ｨｨ0204 ｨｨ04 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ. 020609ｨｰｨｨ00ｨｪｨｮｨｰ04 ｨ 0605ｨｹ03ｨｨ02 ｨｮ09070201ｨｨ 09 070605ｨｮ ﾂ02ｨｪｨｨｨｨ ｨｮ09ｨｰ06ｨｦ ﾂｨｨ090401 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬ, ｨｺ06ｨｰ06080402 0609ｨｪ0609ｨ ｨｪ04 ｨｪｨ 0607ｨｰｨｨｨｬｨｨ04ｨ 02ｨｨｨｨ 090609ｨｰｨ 09ｨ 05ｨｨ07060906ｨｬ ｨｨ 07ｨ 08ｨ ｨｬ02ｨｰ080609 07080602020909ｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ. 00 ｨｪｨ 09ｨｰ0607ｨｴ02ｨｬ 06ｨ 04060802 08ｨ 0909ｨｬｨ ｨｰ08ｨｨ09ｨ 06ｨｰ0907 ｨｬ0201ｨ ｨｪｨｨ04ｨｬ04 0102ｨｦ09ｨｰ09ｨｨ07 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609, 07ｨ 08ｨ ｨｬ02ｨｰ0804, 06ｨｺｨ 040409ｨ 06ｨｴｨｨ02 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰｨｨ09ｨｪ04ｨｦ 05000002ｨｺｨｰ ｨｨ ｨｬ02ｨｰ060104, ｨｪｨ ｨｨｨ 06050202 ﾂｨ 09ｨｰ06 0708ｨｨｨｬ02ｨｪ0702ｨｬ0402 09 ｨｨ09090502010609ｨ ｨｪｨｨ0701. 03ｨ 08ｨ ｨｬ02ｨｰ0804 06ｨ 09ｨｮ0301ｨ 06ｨｰ0907 09 2 ｨｰ06 ﾂ02ｨｺ 040802ｨｪｨｨ07: 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪｨ 07 000608ｨｬｨ (0904ｨ 0608 090609ｨｰｨ 09ｨ 05ｨｨ07ｨｨ01ｨｪ060006 ｨ ｨｨ09050607 ｨｨ 08ｨ 04ｨｬ0208ｨ 05ｨｨ07060906ｨｬ, 070601ｨ 0608 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609, ｨｬｨ 090906090602 090606ｨｰｨｪ060302ｨｪｨｨ02 07080207ｨ 08ｨ ｨｰ/05ｨｨ07ｨｨ01, 08ｨ 0907080201020502ｨｪｨｨ02 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ 0706 06ｨ 02 09ｨｰ060806ｨｪ04 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 ｨ ｨｨ09050607) ｨｨ ｨｰ0201ｨｪ06050600ｨｨ ﾂ0209ｨｺｨｨ02 00ｨ ｨｺｨｰ060804 (080203ｨｨｨｬ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 ｨｨ 09ｨｮ03ｨｺｨｨ). 080506 ﾂ02090402 09050609ｨ : 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ07, 05ｨｨ07060906ｨｬ04, ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608, 090609ｨｰｨ 09. 07ｨｪｨｨ09020809ｨ 05ｨｹｨｪ0609ｨｰｨｹ 090906ｨｦ09ｨｰ09 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 ｨｪ0609ｨｨｨｰ020507 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 07080201070605ｨ 00ｨ 02ｨｰ 03ｨｨ0806ｨｺｨｨ02 090604ｨｬ0603ｨｪ0609ｨｰｨｨ 020006 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ07, 060906ｨ 02ｨｪｨｪ06 09 01ｨｨｨｬｨｨ06ｨｰ0208ｨ 07ｨｨｨｨ 06ｨｪｨｺ06050600ｨｨ ﾂ0209ｨｺｨｨ01 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ [1, 2]. 0201ｨｪｨ ｨｺ06 0005ｨ 09ｨｪ04ｨｬ 0708020707ｨｰ09ｨｰ09ｨｨ02ｨｬ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ07 ｨｨ01 09 ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ 0708ｨ ｨｺｨｰｨｨｨｺ02 0709050702ｨｰ0907 ｨｪ02ｨｮ09ｨｰ06ｨｦ ﾂｨｨ090609ｨｰｨｹ 09 0708060202090902 0108ｨ ｨｪ02ｨｪｨｨ07. 08ｨｪｨ 05ｨｨ04 05ｨｨｨｰ0208ｨ ｨｰｨｮ0804 0706ｨｺｨ 040409ｨ 02ｨｰ, ﾂｨｰ06 070208090702ｨｺｨｰｨｨ09ｨｪ04ｨｬ ｨｪｨ 0708ｨ 090502ｨｪｨｨ02ｨｬ 09ｨｰｨ ｨ ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ, 07080201ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨｪ06ｨｦ 010507 09ｨｪｨｮｨｰ08ｨｨ0902ｨｪｨｪ060006 0909020102ｨｪｨｨ07, 0709050702ｨｰ0907 ｨｬ02ｨｰ0601 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ06ｨｪｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ. 09ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ07 ｪ 05ｨｰ06 07080602020909 09ｨｰｨ ｨ ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ, 0708ｨｨ ｨｺ06ｨｰ060806ｨｬ 08ｨ 09ｨｰ090608 07080207ｨ 08ｨ ｨｰｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ 02ｨｰ0907, ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 08ｨ 09ｨｰ090608ｨｨｨｰ020507 (09 ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ0902 0905ｨｮ ﾂｨ 0209 05ｨｰ06 090601ｨ ) ｨｮｨｬ02ｨｪｨｹ03ｨ 02ｨｰ0907 0702080906ｨｪｨ ﾂｨ 05ｨｹｨｪ06 ｨｬ02ｨｰ060106ｨｬ 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨｨｨ (07020809ｨｨ ﾂｨｪｨ 07 09ｨｮ03ｨｺｨ ), ｨ 04ｨ ｨｰ02ｨｬ ｨｬ02ｨｰ060106ｨｬ 0102090608ｨ 02ｨｨｨｨ (09ｨｰ0608ｨｨ ﾂｨｪｨ 07 09ｨｮ03ｨｺｨ ) [3 ｨC 6]. 0308ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 010507 070609040302ｨｪｨｨ07 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0609ｨｰｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 000608ｨｬ (090908) 0609ｨｪ0609ｨ ｨｪ06 ｨｪｨ 0708020106ｨｰ0908ｨ ｨｴ02ｨｪｨｨｨｨ 00ｨｨ01080605ｨｨ04ｨ ｨｺｨ ｨｺ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 000609000605ｨｨ07ｨｨ010609 (0809), ｨｰｨ ｨｺ ｨｨ 05ｨ ｨ ｨｨ05ｨｹｨｪ0401 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 0902ｨｴ0209ｨｰ09, ｨ 0708060202090904 01ｨｨｨｬｨｨ- ﾂ0209ｨｺ06ｨｦ ｨｨ 00ｨｨ04ｨｨ ﾂ0209ｨｺ06ｨｦ 01020008ｨ 01ｨ 02ｨｨｨｨ 0901020803ｨｨ09ｨ 06ｨｰ0907 ｨｪｨｨ04ｨｺ06ｨｦ ｨｬ060502ｨｺｨｮ050708ｨｪ06ｨｦ 07060109ｨｨ03ｨｪ0609ｨｰｨｹ06 05ｨｨ07ｨｨ010609 09 ｨｰ0902080106ｨｦ 00ｨ 0402 [7, 8]. 08 090603ｨ 0502ｨｪｨｨ06, 09ｨ ｨｬｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ07 ｨｬ060302ｨｰ 0708ｨｨ090601ｨｨｨｰｨｹ ｨｺ 08ｨ 0408ｨｮ0302ｨｪｨｨ06 ｨ ｨｨ090506ｨｦｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04 05ｨｨ07060906ｨｬ, 070605ｨｰ06ｨｬｨｮ ｨｪ0206ｨ 010601ｨｨｨｬ06 070806090601ｨｨｨｰｨｹ 0202 09 0607080201020502ｨｪｨｪ06ｨｬ 080203ｨｨｨｬ02 ｨｨ 09 0106ｨ ｨ 090502ｨｪｨｨ02ｨｬ 09090706ｨｬ0600ｨ ｨｰ0205ｨｹｨｪ0401 0902ｨｴ0209ｨｰ09, 06ｨ 02090702 ﾂｨｨ09ｨ 06ｨｴｨｨ01 09060108ｨ ｨｪ02ｨｪｨｨ02 ｨ ｨｨ090506ｨｦｨｪ0401 09ｨｰ08ｨｮｨｺｨｰｨｮ08 [9]. 040605ｨｹ 09090706ｨｬ0600ｨ ｨｰ0205ｨｹｨｪ0401 0902ｨｴ0209ｨｰ09 ｪ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609 09 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ, 070601050203ｨ ｨｴ02ｨｦ 090409ｨｮ03ｨｨ09ｨ ｨｪｨｨ06 09ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ07 05ｨｨ07060906ｨｬ ｨ 0204 09070202ｨｨｨ 05ｨｹｨｪ0401 04ｨ ｨｴｨｨｨｰｨｪ0401 0902ｨｴ0209ｨｰ09 ｪ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609 0708ｨｨ090601ｨｨｨｰ ｨｺ ｨｨ01 0905ｨｨ07ｨｪｨｨ06 ｨｨ ｨ 00080200ｨ 02ｨｨｨｨ, ｨ ｨｰｨ ｨｺ0302 ｨｺ 0904ｨｰ02ｨｺｨ ｨｪｨｨ06 09ｨｺ0506 ﾂ02ｨｪｨｪ060006 0906010608ｨ 09ｨｰ090608ｨｨｨｬ060006 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ060006 0902ｨｴ0209ｨｰ09ｨ (0900) [10]. 08060001ｨ 05ｨｨ07ｨｨ01ｨｪｨ 07 ｨｬ02ｨｬｨ 08ｨ ｨｪｨ 010609ｨｰｨｨ00ｨ 02ｨｰ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 00ｨ 040609060006 07020802010601ｨ (06 00.07. ), ｨｨｨｪｨｺｨ 0709ｨｮ05ｨｨ080609ｨ ｨｪｨｪ0602 0900 050200ｨｺ06 0904090906ｨ 060301ｨ 02ｨｰ0907 ｨｨ04 05ｨｨ07060906ｨｬ 0708ｨｨ 0702080201060102 ｨｨ04 000205020906ｨｦ 00ｨ 0404 09 03ｨｨ01ｨｺ06ｨｺ08ｨｨ09ｨｰｨ 0505ｨｨ ﾂ0209ｨｺｨｮ06. 0808ｨｨ06070806ｨｰ02ｨｺｨｰ0608, 0708020106ｨｰ0908ｨ ｨｴｨ 07 00ｨ 04060904ｨｦ 07020802010601, 04ｨ ｨｴｨｨｨｴｨ 02ｨｰ 05ｨｨ07060906ｨｬ04 06ｨｰ 0706090802030102ｨｪｨｨ07 ｨｺ08ｨｨ09ｨｰｨ 0505ｨ ｨｬｨｨ 05ｨｹ01ｨ 0708ｨｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨｨｨ, ｨ ｨｰｨ ｨｺ0302 ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ02ｨｰ ｨｨ01 0905ｨｨ07ｨｪｨｨ02 ｨｨ ｨ 00080200ｨ 02ｨｨ06. 0206ｨ ｨ 090502ｨｪｨｨ02 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ 09 090601ｨｪｨｮ06 00ｨ 04ｨｮ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ (09ｨｪｨｮｨｰ08ｨｨ ｨｨ 09ｨｪｨ 08ｨｮ03ｨｨ) 0702080201 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02ｨｬ 09 070609050201ｨｮ06ｨｴ02ｨｦ 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ02ｨｦ 0706040906050702ｨｰ 07080201ｨｮ07080201ｨｨｨｰｨｹ 00ｨ 0406090602 08ｨ 0401020502ｨｪｨｨ02 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｺ06ｨｬ070604ｨｨ02ｨｨｨｨ ｨｨ 07080201060108ｨ ｨｪｨｨｨｰｨｹ ｨｨｨｪｨｺｨ 0709ｨｮ05ｨｨ080609ｨ ｨｪｨｪ0602 0900 06ｨｰ 0904ｨｰ02ｨｺｨ ｨｪｨｨ07, ｨ ｨｰｨ ｨｺ0302 09060108ｨ ｨｪｨｨｨｰｨｹ 0907060906ｨ ｨｪ0609ｨｰｨｹ 05ｨｨ07060906ｨｬ ｨｺ 080200ｨｨ0108ｨ ｨｰｨ 02ｨｨｨｨ [11]. 08 05000002ｨｺｨｰｨｨ09ｨｪ04ｨｬ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｬ 06ｨｰｨｪ060907ｨｰ0907 09060201ｨｨｨｪ02ｨｪｨｨ07, 0708ｨｨｨｪｨ 01050203ｨ ｨｴｨｨ02 ｨｺ 08ｨ 04ｨｪ04ｨｬ ｨｺ05ｨ 0909ｨ ｨｬ 01ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ01 0902ｨｴ0209ｨｰ09. 06ｨｰ06 0907ｨｨ08ｨｰ04 (05ｨｰｨｨ0502ｨｪ0005ｨｨｨｺ0605ｨｹ, 1 7-07080607ｨｨ0502ｨｪ0005ｨｨｨｺ0605ｨｹ, 0005ｨｨ020208ｨｨｨｪ), ｨ ｨｬｨｨ0104 (01ｨｨｨｬ02ｨｰｨｨ05ｨ 0202ｨｰｨ ｨｬｨｨ01), 06ｨｺ09ｨｨ0104 (01ｨｨｨｬ02ｨｰｨｨ0509ｨｮ05ｨｹ0006ｨｺ09ｨｨ01), ｨｨ09ｨｺｨｮ0909ｨｰ0902ｨｪｨｪ0402 070605ｨｨｨｬ020804 (070605ｨｨ09ｨｨｨｪｨｨ0507ｨｨ08080605ｨｨ0106ｨｪ, 06ｨｺ09ｨｨ05ｨｰｨｨ05ｨｨ080609ｨ ｨｪｨｪ04ｨｦ ｨｺ08ｨ 01ｨｬｨ 05, 070605ｨｨ05ｨｰｨｨ0502ｨｪ0005ｨｨｨｺ0605ｨｹ), ｨｮ00050209060104 (09ｨ 01ｨ 080604ｨ, ｨｬｨ ｨｪｨｪｨｨｨｰ, 05ｨ ｨｺｨｰ0604ｨ, ｨｰ080200ｨ 050604ｨ ｨｨ 0108.) [12 ｨC 16]. 09ｨｨｨｬｨｨｨｺ06-00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ 03ｨｮ08ｨｪｨ 05. 0606ｨｬ 46, 01 4, 2012 29
130808ｨｨ06070806ｨｰ02ｨｺｨｰ060804 06ｨ 02090702 ﾂｨｨ09ｨ 06ｨｰ 070806ｨｰ02ｨｺｨｰｨｨ09ｨｪ04ｨｦ 05000002ｨｺｨｰ ｨ 05ｨ 000601ｨ 0807 2 ｨｬ0201ｨ ｨｪｨｨ04ｨｬｨ ｨｬ: 0702080904ｨｦ 09090704ｨ ｨｪ 09 04ｨ ｨｬ02ｨｴ02ｨｪｨｨ02ｨｬ 09060104; 09ｨｰ060806ｨｦ ｪ 09 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02ｨｬ ｨｬｨ ｨｰ08ｨｨ0204 [11, 16]. 00070208090402 00ｨｨ0706ｨｰ0204ｨ 04ｨ ｨｬ02ｨｴ02ｨｪｨｨ07 ｨｬ060502ｨｺｨｮ05 09060104 ｨｬ060502ｨｺｨｮ05ｨ ｨｬｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨ 0405ｨ 0708020105060302ｨｪｨ J. H. Crowe, 09 ｨｪ02ｨｦ 0006090608ｨｨ050609ｨｹ 06 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨｨｨ ｨｬ020301ｨｮ ｨｬ060502ｨｺｨｮ05ｨ ｨｬｨｨ 09ｨ 01ｨ 08ｨ ｨｨ 0006050609ｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ 0809, ﾂｨｰ06 0708ｨｨ090601ｨｨｨｰ ｨｺ 09ｨｪｨｨ0302ｨｪｨｨ06 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 00ｨ 040609060006 07020802010601ｨ (06 00.07. ) 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04 04ｨ 09 ﾂ02ｨｰ 0909ｨｰ08ｨ ｨｨ09ｨ ｨｪｨｨ07 ｨｪｨ ｨｬ0209ｨｰ06 ｨｬ060502ｨｺｨｮ05 09060104 ｨｬ060502ｨｺｨｮ05 09ｨ 01ｨ 08ｨ, 0708ｨｨ 05ｨｰ06ｨｬ 09ｨｪｨｨ03ｨ 06ｨｰ0907 00ｨ ｨｪ-010208-00ｨ ｨ 05ｨｹ09060904 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 ｨｬ020301ｨｮ ｨ 02ｨｨ05ｨｹｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｨ 0809 [17, 18]. 01ｨ 070609020801ｨｪ0609ｨｰｨｨ ｨ ｨｨ09050607 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04 000608ｨｬｨｨ08ｨｮ02ｨｰ0907 ｨｬｨｪ06030209ｨｰ0906 09060106080601ｨｪ0401 0909070402ｨｦ ｨｬ020301ｨｮ 09ｨ 01ｨ 0806ｨｬ ｨｨ 0809 [19]. 02ｨ 08ｨ 040609ｨ ｨｪｨｨ02 0302 ｨｬｨ ｨｰ08ｨｨ0204 09090704ｨ ｨｪ06 09 ｨｰ02ｨｬ, ﾂｨｰ06 0708ｨｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨｨｨ 08ｨ 09ｨｰ090608 09ｨ 01ｨ 08ｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨｨ08ｨｮ02ｨｰ0907, ｨ 0906 090802ｨｬ07 09ｨｮ03ｨｺｨｨ 000608ｨｬｨｨ08ｨｮ02ｨｰ0907 09ｨ 01ｨ 08ｨｪｨ 07 ｨｬｨ ｨｰ08ｨｨ02ｨ, ｨｺ06ｨｰ0608ｨ 07 06ｨ 05ｨ 01ｨ 02ｨｰ ｨ 0605ｨｹ0306ｨｦ 090704ｨｺ0609ｨｰｨｹ06 ｨｨ ｨｪｨｨ04ｨｺ06ｨｦ 07060109ｨｨ03ｨｪ0609ｨｰｨｹ06 ｨｨ 07080201060108ｨ ｨｪ0702ｨｰ 090204ｨｨｨｺｨｮ0504 06ｨｰ 0905ｨｨ07ｨｪｨｨ07, ｨ 00080200ｨ 02ｨｨｨｨ, 04ｨ ｨｴｨｨｨｴｨ 02ｨｰ 05ｨｨ07ｨｨ01ｨｪ04ｨｦ 090506ｨｦ 06ｨｰ 0706090802030102ｨｪｨｨ07 ｨｺ08ｨｨ09ｨｰｨ 0505ｨ ｨｬｨｨ 05ｨｹ01ｨ 0708ｨｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨｨｨ. 080806ｨｬ02 ｨｰ060006, 0708ｨｨ09ｨｮｨｰ09ｨｰ09ｨｨ02 ｨｬｨ ｨｰ08ｨｨ0204 ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ02ｨｰ ｨｺ06ｨｪ000608ｨｬｨ 02ｨｨ06ｨｪｨｪ0402 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07, 09090704ｨ ｨｪｨｪ0402 09 00ｨ 04060904ｨｬ 0702080201060106ｨｬ 05ｨｨ07ｨｨ010609, ｨ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 ｨｬ020301ｨｮ 070609020801ｨｪ0609ｨｰｨｹ06 05ｨｨ07060906ｨｬ ｨｨ ｨｬｨ ｨｰ08ｨｨ0202ｨｦ 09ｨｪｨｨ03ｨ 02ｨｰ 070609020801ｨｪ0609ｨｰｨｪ0602 ｨｪｨ ｨｰ070302ｨｪｨｨ02, 09ｨｰｨ ｨ ｨｨ05ｨｨ04ｨｨ08ｨｮ07 090409ｨｮ0302ｨｪｨｪ0402 05ｨｨ07060906ｨｬ04 [9, 20]. 00ｨ 03ｨｪ06, ﾂｨｰ06 0102ｨｦ09ｨｰ09ｨｨ02 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609 0708060709050702ｨｰ0907 0708ｨｨ 090601020803ｨ ｨｪｨｨｨｨ 09060104 ｨｬ02ｨｪ0202 20 % ｨｪｨ 05ｨｰｨ 0702 07020809ｨｨ ﾂｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ [21]. 050601020803ｨ ｨｪｨｨ02 09060104 ｨｰｨ ｨｺ0302 0905ｨｨ0702ｨｰ ｨｪｨ 09ｨｺ0506- ﾂ02ｨｪｨｨ02 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ060006 07080207ｨ 08ｨ ｨｰｨ, ｨ 0609ｨｰｨ ｨｰ06 ﾂｨｪｨ 07 090601ｨ 0709050702ｨｰ0907 0708ｨｨ ﾂｨｨｨｪ06ｨｦ 09ｨｪｨｨ0302ｨｪｨｨ07 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 06ｨ 08ｨ 040609ｨ ｨｪｨｨ07 ｨｬｨ ｨｰ08ｨｨ0204 (06 ｨｬ ). 0604090209ｨｰｨｪ06, ﾂｨｰ06 06 ｨｬ ｨｰ080200ｨ 05060404 090609ｨｰｨ 09050705ｨ ｨC 99,7 ｨｨ ｨC 40,3 紊 0708ｨｨ 0609ｨｰｨ ｨｰ06 ﾂｨｪ06ｨｬ 090601020803ｨ ｨｪｨｨｨｨ 09060104 ｨｬ02ｨｪ0202 0,5 ｨｨ 6,5 % 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06 [22]. 0604ｨｮ ﾂ02ｨｪｨｨ02 0905ｨｨ07ｨｪｨｨ07 ﾂｨｨ0905ｨ 0609ｨｰｨ ｨｰｨｺ0609 000506ｨｺ060404 ｨｪｨ 09ｨｺ0506- ﾂ02ｨｪｨｨ02 0902ｨｴ0209ｨｰ09 09 05ｨｨ07060906ｨｬ04 0706ｨｺｨ 04ｨ 0506, ﾂｨｰ06 ｨｪｨ ｨｨｨ 0605ｨｹ03ｨｨｨｦ 0708060202ｨｪｨｰ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 09060108ｨ ｨｪ07050907 0708ｨｨ ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ 09 2 0609ｨｰｨ ｨｰｨｺｨ ｨｬｨｨ 000506ｨｺ060404 [1]. 0604 09090201 ｨｨ04ｨｮ ﾂ02ｨｪｨｪ0401 09 ｨｪｨ 09ｨｰ0607ｨｴ0202 090802ｨｬ07 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ06080609 ｨｪｨ ｨｨｨ 06050202 05000002ｨｺｨｰｨｨ09ｨｪ04ｨｬｨｨ 010507 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 0709050706ｨｰ0907 01ｨｨ09ｨ 01ｨ 08ｨｨ0104 000506ｨｺ060404 ｪ 09ｨ 01ｨ 080604ｨ (1 7-D-000506ｨｺ0607ｨｨ08ｨ ｨｪ0604ｨｨ01-1 7-D-0008ｨｮｨｺｨｰ0600ｨｮ08ｨ ｨｪ0604ｨｨ01) ｨｨ ｨｰ080200ｨ 050604ｨ (1 7-D-000506ｨｺ0607ｨｨ08ｨ ｨｪ0604ｨｨ01-1 7-D-000506ｨｺ0607ｨｨ08ｨ ｨｪ0604ｨｨ01). 06ｨｰｨｨ 09060201ｨｨｨｪ02ｨｪｨｨ07, ｨ 05ｨ 000601ｨ 0807 0607ｨｰｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ 06 ｨｬ ｨｰ080200ｨ 05060404 (ｨC 110 紊) ｨｨ 09ｨ 01ｨ 08060404 (ｨC 65 紊), 06ｨ 02090702 ﾂｨｨ09ｨ 06ｨｰ 09060108ｨ ｨｪ02ｨｪｨｨ02 070806ｨｪｨｨ02ｨ 02ｨｬ0609ｨｰｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04, ｨ ｨｰｨ ｨｺ0302 0708020707ｨｰ09ｨｰ09ｨｮ06ｨｰ 0904ｨｰ02ｨｺｨ ｨｪｨｨ06 090601020803ｨｨｨｬ060006 090204ｨｨｨｺｨｮ05 0708ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ [23 ｨC 25]. 020507 05000002ｨｺｨｰｨｨ09ｨｪ06ｨｦ 04ｨ ｨｴｨｨｨｰ04 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608 0106050302ｨｪ ｨｪｨ 010601ｨｨｨｰｨｹ0907 09ｨｪｨｮｨｰ08ｨｨ ｨｨ 09ｨｪｨ 08ｨｮ03ｨｨ 05ｨｨ07060906ｨｬ, ｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ07 020006 ｨｨ 09ｨｺ0506 ﾂ02ｨｪｨｪ060006 0902ｨｴ0209ｨｰ09ｨ 01060503ｨｪｨ ｨ 04ｨｰｨｹ 07060106ｨ 08ｨ ｨｪｨ ｨｰｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, ﾂｨｰ06ｨ 04 06ｨ 02090702 ﾂｨｨｨｰｨｹ 0609ｨｬ06050708ｨｪ0609ｨｰｨｹ ｨｨｨｪｨｰ08ｨ -/05ｨｺ09ｨｰ08ｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 07080609ｨｰ08ｨ ｨｪ09ｨｰ09ｨ. 00 [15] 0904ｨ 0608 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｨ 020006 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 070806090601ｨｨ05ｨｨ, 060202ｨｪｨｨ09ｨ 07 08ｨ 04ｨｬ0208 070605ｨｮ ﾂｨ 02ｨｬ0401 05ｨｨ07060906ｨｬ, ｨｺｨ ｨｺ 09 0708060202090902 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07-08ｨ 04ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07, ｨｰｨ ｨｺ ｨｨ 0106/0706090502 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ06ｨｪｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ. 0809ｨｰ0608ｨ ｨｬｨｨ 070605ｨｮ ﾂ02ｨｪ04 ｨｬ06ｨｪ0605ｨ ｨｬ0205050708ｨｪ0402 05ｨｨ07060906ｨｬ04 09 08ｨ 04ｨｬ020806ｨｬ 06ｨｺ060506 100 ｨｪｨｬ ｨｪｨ 0609ｨｪ060902 01ｨｨ09ｨｰ02ｨ 0806ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ0505ｨｰｨ ｨｪ0605ｨ ｨｬｨｨｨｪｨ -030601-2000, 05ｨｨ040609ｨｰ02ｨ 0806ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ050005ｨｨ020208ｨｨｨｪｨ ｨｨ 01ｨｨ09ｨｰ02ｨ 0806ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪｨ. 02ｨ ｨｪｨｪ0402 090609ｨｰｨ 0904 0702080906ｨｪｨ ﾂｨ 05ｨｹｨｪ06 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ 05ｨｨ ｨ 0204 0106ｨ ｨ 090502ｨｪｨｨ07 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ, 0708ｨｨ 05ｨｰ06ｨｬ 08ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ ｨｮ090205ｨｨ ﾂｨｨ09ｨ 050907 ｨ 06050202 ﾂ02ｨｬ 09 2 08ｨ 04ｨ (06ｨｺ060506 260 ｨｪｨｬ). 00 0708060202090902 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 09 08ｨ 0405ｨｨ ﾂｨｪ04ｨｬｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｬｨｨ (05ｨ ｨｺｨｰ060406ｨｦ, ｨｰ080200ｨ 05060406ｨｦ, 000506ｨｺ060406ｨｦ ｨｨ ｨｬｨ ｨｪｨｪｨｨｨｰ06ｨｬ) 0708ｨｨ ｨｬ06050708ｨｪ06ｨｬ 090606ｨｰｨｪ060302ｨｪｨｨｨｨ 05ｨｨ07ｨｨ01/ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608 1:5 0906 09090201 0905ｨｮ ﾂｨ 0701 070806ｨｨ09010601ｨｨ0506 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 09080201ｨｪ020006 01ｨｨｨ ｨｬ02ｨｰ08ｨ 090204ｨｨｨｺｨｮ05 (000506ｨｺ0604ｨ ｪ 175 ｨｪｨｬ, 05ｨ ｨｺｨｰ0604ｨ ｪ 160 ｨｪｨｬ, ｨｰ080200ｨ 050604ｨ ｪ 150 ｨｪｨｬ, ｨｬｨ ｨｪｨｪｨｨｨｰ ｪ 160 ｨｪｨｬ), ｨｪ06 ｨｪ02 ｨｰｨ ｨｺ 04ｨ ｨｬ02ｨｰｨｪ06, ｨｺｨ ｨｺ 010507 05ｨｨ07060906ｨｬ ｨ 0204 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ. 09ｨｨ07060906ｨｬ04, 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0402 09 000506ｨｺ060406ｨｦ, ｨｰ080200ｨ 05060406ｨｦ ｨｨ 05ｨ ｨｺｨｰ060406ｨｦ, 0708ｨｨ ｨｬ06050708ｨｪ06ｨｬ 090606ｨｰｨｪ060302ｨｪｨｨｨｨ 05ｨｨ07ｨｨ01/ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608 1:10 09060108ｨ ｨｪ0705ｨｨ 0702080906ｨｪｨ ﾂｨ 05ｨｹｨｪ04ｨｦ 08ｨ 04ｨｬ0208 (1 7 100 ｨｪｨｬ) [15]. 00 08070102 ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 ｨｪｨ ｨｨｨ 06050202 07060101060107ｨｴｨｨｨｬｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｬｨｨ 0709050706ｨｰ0907 05ｨ ｨｺｨｰ0604ｨ ｨｨ 09ｨ 01ｨ - 09ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0402 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0402 07080207ｨ 08ｨ ｨｰ04, 0708ｨｨｨｬ02ｨｪ0702ｨｬ0402 09 ｨｺ05ｨｨｨｪｨｨｨｺ02 03080207ｨ 08ｨ ｨｰ (0102ｨｦ09ｨｰ09ｨｮ06ｨｴ0202 0902ｨｴ0209ｨｰ0906) 06ｨｨ07 ｨｪ0609ｨｨｨｰ020507 (090609ｨｰｨ 09) / ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608* 0306ｨｺｨ 04ｨ ｨｪｨｨ07 ｨｺ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ06 030806ｨｨ04090601ｨｨｨｰ0205ｨｹ AmBisome (ｨ ｨｬ0006ｨｰ0208ｨｨ02ｨｨｨｪ 00) 09ｨｨ07060906ｨｬ04 (00050809, 0106050209ｨｰ0208ｨｨｨｪ) / 09ｨ 01ｨ 080604ｨ 05ｨｨ09ｨｰ02ｨｬｨｪ0402 0008ｨｨｨ ｨｺ06090402 ｨｨｨｪ0002ｨｺ02ｨｨｨｨ NeXstar Pharmaceuticals (050108) Myocet (0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪ) 09ｨｨ07060906ｨｬ04 (080809, 0106050209ｨｰ0208ｨｨｨｪ) / 05ｨ ｨｺｨｰ0604ｨ 0002ｨｰｨ 09ｨｰｨ 0404 08ｨ ｨｺｨ ｨｬ060506 ﾂｨｪ06ｨｦ 030205020404 Elan Corporation (050108) Nyotran (ｨｪｨｨ09ｨｰｨ ｨｰｨｨｨｪ) 09ｨｨ07060906ｨｬ04 (02000809, 02000801) / 0102ｨｺ09ｨｰ080604ｨ 05ｨｨ09ｨｰ02ｨｬｨｪ0402 0008ｨｨｨ ｨｺ06090402 ｨｨｨｪ0002ｨｺ02ｨｨｨｨ Aronex Pharmaceuticals (050108) 09ｨｨ070600020806ｨｪ (ｨｨｨｪｨｰ020800020806ｨｪｨ 05ｨｹ00ｨ 09ｨｨ07060906ｨｬ04 (050202ｨｨｨｰｨｨｨｪ, 0106050209ｨｰ0208ｨｨｨｪ) 0209ｨｰ0804ｨｦ 000207ｨ ｨｰｨｨｨｰ 00, 010806ｨｪｨｨ ﾂ0209ｨｺｨｨｨｦ Jardan (09060809ｨ ｨｰｨｨ07) 2b) / 05ｨ ｨｺｨｰ0604ｨ 000207ｨ ｨｰｨｨｨｰ 05 09ｨｨ07060005ｨ 0906ｨｪ (ｨｺ09020802ｨｨｨｰｨｨｨｪ) 09ｨｨ07060906ｨｬ04 (050202ｨｨｨｰｨｨｨｪ) / 05ｨ ｨｺｨｰ0604ｨ 04ｨ ｨｪ02ｨｪｨｨ07 ｨｨ 070609050206070208ｨ 02ｨｨ06ｨｪｨｪ0402 08ｨ ｨｪ04 0806000609ｨｨ0204, ｨｺ0208ｨ ｨｰｨｨｨｰ04 09ｨｨ060502ｨｺ (07ｨｺ08ｨ ｨｨｨｪｨ ) 00ｨｨ04ｨｮ01ｨｨｨｪ (090208ｨｰ0207060800ｨｨ08ｨｨｨｪ) 09ｨｨ07060906ｨｬ04 (02000809, 0801) / 05ｨ ｨｺｨｰ0604ｨ 020507 0006ｨｰ0601ｨｨｨｪｨ ｨｬｨｨ ﾂ0209ｨｺ06ｨｦ ｨｰ0208ｨ 07ｨｨｨｨ 09 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨｨｨ Novartis Pharma (010902ｨｦ02ｨ 08ｨｨ07) 09ｨｨ07060106ｨｺ09 (0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪ) 09ｨｨ07060906ｨｬ04 (050202ｨｨｨｰｨｨｨｪ) /05ｨ ｨｺｨｰ0604ｨ 05ｨ 08ｨｺ06ｨｬｨ 08ｨ 070603ｨｨ, ｨｬ02ｨｰｨ 09ｨｰｨ 0404 08ｨ ｨｺｨ 07ｨｨ ﾂｨｪｨｨｨｺ0609 09ｨｨ060502ｨｺ (07ｨｺ08ｨ ｨｨｨｪｨ ) 0402ｨ 00020806ｨｪ-0209-05ｨｨ07ｨｨｨｪｨｰ (ｨｨｨｪｨｰ020800020806ｨｪ-ｨ 05ｨｹ00ｨ 09ｨｨ07060906ｨｬ04 (050202ｨｨｨｰｨｨｨｪ, 0106050209ｨｰ0208ｨｨｨｪ) 0209ｨｰ0804ｨｦ 000207ｨ ｨｰｨｨｨｰ 00, 010806ｨｪｨｨ ﾂ0209ｨｺｨｨｨｦ 0002-0002ｨｺｨｰ0608-000201ｨｨｨｺｨ (04060909ｨｨ07) 2b) / 05ｨ ｨｺｨｰ0604ｨ 07ｨ ｨｰｨｨｨｰ 05 * ｪ 00050809 ｪ 00ｨｨ0108060002ｨｪｨｨ04ｨｨ080609ｨ ｨｪｨｪ04ｨｦ 0906020904ｨｦ 00060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪ; 080809 ｪ 07ｨｨ ﾂｨｪ04ｨｦ 00060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪ; 02000809 ｪ 01ｨｨｨｬｨｨ08ｨｨ09ｨｰ06ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪ; 02000801 ｪ 01ｨｨｨｬｨｨ08ｨｨ09ｨｰ06ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ050005ｨｨ020208ｨｨｨｪ; 0801 ｪ 00060900ｨ ｨｰｨｨ01ｨｨ050005ｨｨ020208ｨｨｨｪ. 30 09ｨｨｨｬｨｨｨｺ06-00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ 03ｨｮ08ｨｪｨ 05. 0606ｨｬ 46, 01 4, 2012
13080604ｨ. 0308ｨｨ 05ｨｰ06ｨｬ 09ｨ 01ｨ 080604ｨ ｨｨ04-04ｨ 05ｨｮ ﾂ0302ｨｦ 08ｨ 09ｨｰ090608ｨｨｨｬ0609ｨｰｨｨ 09 09060102 ｨｪ02 0609050603ｨｪ0702ｨｰ ｨｮ09050609ｨｨ07 070609050201ｨｮ06ｨｴ020006 00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺ060006 ｨ ｨｪｨ 05ｨｨ04ｨ. 0609090502010609ｨ ｨｪｨｨ07 0905ｨｨ07ｨｪｨｨ07 ｨｰｨｨ07ｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｪｨ ｨｺｨ ﾂ0209ｨｰ0906 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 0006ｨｰ0601ｨｨｨｰｨ 04ｨｨｨｪｨ 070806090601ｨｨ05ｨｨ, 060202ｨｪｨｨ09ｨ 07 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0900. 0306ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 0909020102ｨｪｨｨ02 09 090609ｨｰｨ 09 05ｨｨ07060906ｨｬ 09ｨ 01ｨ 08060404 0706040906050702ｨｰ 070806090601ｨｨｨｰｨｹ 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ06ｨｪｨｪｨｮ06 09ｨｮ03ｨｺｨｮ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ ｨ 0204 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 08ｨ 04ｨｬ0208ｨ 090204ｨｨｨｺｨｮ05 ｨｨ 09 09060108ｨ ｨｪ02ｨｪｨｨ02ｨｬ 09040906ｨｺ06ｨｦ 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0900 [26]. 0604ｨｮ ﾂ02ｨｪｨｨ02 0905ｨｨ07ｨｪｨｨ07 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｪｨ 08ｨ 04ｨｬ0208 ｨｨ 09ｨｺ0506 ﾂ02ｨｪｨｨ02 0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪｨ 09 09090203020708ｨｨ0006ｨｰ06090502ｨｪｨｪ0402, 04ｨ ｨｬ0608060302ｨｪｨｪ0402 ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0402 ｨｰ0208ｨｬ06 ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｹｨｪ0402 05ｨｨ07060906ｨｬ04 070604090605ｨｨ0506 0609ｨｰｨ ｨｪ0609ｨｨｨｰｨｹ0907 ｨｪｨ ｨｪｨ ｨｨｨ 06050202 0708ｨｨ02ｨｬ0502ｨｬ06ｨｬ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ060802 010507 01ｨ ｨｪｨｪ06ｨｦ 0908 ｪ 4 % 08ｨ 09ｨｰ09060802 09ｨ 01ｨ 08060404 (01ｨｨｨ ｨｬ02ｨｰ08 090204ｨｨｨｺｨｮ05 0706090502 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 165 ｨC 175 ｨｪｨｬ; 09ｨｺ0506 ﾂ02ｨｪｨｨ02 0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪｨ 09 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0402 ｨｰ0208ｨｬ0605ｨｨ07060906ｨｬ04 090609ｨｰｨ 09ｨｨ0506 74 %) [27]. 00 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 060202ｨｪｨｺｨｨ 0609ｨｪ0609ｨｪ0401 ｨ ｨｨ0600ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨ01 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ, ｨｰｨ ｨｺｨｨ01 ｨｺｨ ｨｺ 09080201ｨｪｨｨｨｦ 01ｨｨｨ ｨｬ02ｨｰ08 05ｨｨ07060906ｨｬ 09 0006ｨｰ060902ｨｪ0906ｨｬ, 0601ｨｪ06080601ｨｪ0609ｨｰｨｹ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ, ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 0900, 09ｨｺ0506 ﾂ02ｨｪｨｪ060006 09 090204ｨｨｨｺｨｮ0504, 09ｨｰ08ｨｮｨｺｨｰｨｮ08ｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ ｨｰｨ ｨｨ 090604ｨｬ0603ｨｪ0609ｨｰｨｹ 020006 080200ｨｨ0108ｨ ｨｰｨ 02ｨｨｨｨ, 09020502ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｪｨ ｨｺ06070502ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰｨ 09 0607ｨｮ010605ｨｨ ｨｨ 020006 070806ｨｰｨｨ09060607ｨｮ0106050209ｨ 07 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 070605ｨｮ ﾂ02ｨｪ 07080207ｨ 08ｨ ｨｰ 000806ｨｰ060406ｨｬ, 05ｨｨ0600ｨｨ05ｨｨ04ｨ ｨｰ 010507 0708ｨｨ0006ｨｰ06090502ｨｪｨｨ07 08ｨ 09ｨｰ090608ｨ 010507 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｦ 12 ｨｬ0003 09 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ060806ｨｬ 09ｨ 01ｨ 08060406ｨｦ [28, 29]. 0308ｨｨ 0904ｨ 060802 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ 010507 090908 05ｨｨ0406ｨｬｨｮ09ｨｰｨｨｨｪｨ ｨｮ09ｨｰｨ ｨｪ06090502ｨｪ06, ﾂｨｰ06 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02 05ｨ ｨｺｨｰ060404 0706040906050702ｨｰ 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｰｨｹ 090601ｨｪｨｮ06 01ｨｨ0907020809ｨｨ06 ｨ 0204 ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 0202050609ｨｰｨｪ0609ｨｰｨｨ, 0601ｨｪ06080601ｨｪ0609ｨｰｨｨ ｨｨ 08ｨ 04ｨｬ0208ｨ 05ｨｨ07060906ｨｬ [30, 31]. 00 01ｨ 05ｨｹｨｪ02ｨｦ03ｨｨ01 ｨｨ09090502010609ｨ ｨｪｨｨ0701 05ｨ ｨｺｨｰ0604ｨｮ 04ｨ ｨｬ02ｨｪｨｨ05ｨｨ ｨｪｨ 09ｨ 01ｨ 080604ｨｮ, ｨｺ06ｨｰ0608ｨ 07 ｨｪ02 ｨｬ0203ｨ 02ｨｰ 090702ｨｺｨｰ08060006ｨｰ06ｨｬ02ｨｰ08ｨｨ- ﾂ0209ｨｺ06ｨｬｨｮ 0607080201020502ｨｪｨｨ06 09ｨｺ0506 ﾂ02ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰｨ. 040605ｨｹ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰ0609 ｨ ｨｨ090506ｨｦｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04 05ｨｨ07060906ｨｬ 080806ｨｬ02 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｪｨ ｨｺｨ ﾂ0209ｨｰ0906 090908 0708ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 0905ｨｨ0706ｨｰ: ｨｰｨｨ07 0809, ｨｪｨ 05ｨｨ ﾂｨｨ02 0106050209ｨｰ0208ｨｨｨｪｨ ｨｨ 070609020801ｨｪ0609ｨｰｨｪ06 ｨｬ0601ｨｨ00ｨｨ02ｨｨ08ｨｮ06ｨｴｨｨ01 0902ｨｴ0209ｨｰ09 09 090609ｨｰｨ 0902 ｨ ｨｨ09050607. 06ｨｨ07 000609000605ｨｨ07ｨｨ01ｨ 0308ｨｨ 000608ｨｬｨｨ080609ｨ ｨｪｨｨｨｨ 0607ｨｰｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｺ06ｨｬ070604ｨｨ02ｨｨｨｨ 010507 05ｨｨ07060906ｨｬ ｨｺ06ｨｪｨｺ0802ｨｰｨｪ060006 0202050209060006 ｨｪｨ 04ｨｪｨ ﾂ02ｨｪｨｨ07 ｨｨ09070605ｨｹ04ｨｮ06ｨｰ0907 08ｨ 0405ｨｨ ﾂｨｪ0402 09ｨｨｨｪｨｰ02ｨｰｨｨ ﾂ0209ｨｺｨｨ02 ｨｨ 0708ｨｨ080601ｨｪ0402 000609000605ｨｨ07ｨｨ0104 (0809). 0602ｨｬ070208ｨ ｨｰｨｮ08ｨ 00ｨ 040609060006 07020802010601ｨ 0809 06ｨ 04 ﾂｨｪ06 060708020102050702ｨｰ0907 0105ｨｨｨｪ06ｨｦ ｨｨ 09ｨｰ020702ｨｪｨｹ06 ｨｪｨ 0904ｨｴ02ｨｪｨｪ0609ｨｰｨｨ ｨ 02ｨｨ05ｨｹｨｪ0401 02020702ｨｦ, ｨｺ06ｨｰ06080402 0901060107ｨｰ 09 020006 090609ｨｰｨ 09. 0205ｨｨｨｪｨｪ0602020706 ﾂ02 ﾂｨｪ0402 ｨｨ ｨｪｨ 0904ｨｴ02ｨｪｨｪ0402 ｨ 02ｨｨ05ｨｹｨｪ0402 020207ｨｨ ｨｨｨｬ0206ｨｰ 0809 09 09040906ｨｺ06ｨｦ 06 00.07. [32]. 0308ｨｨ080601ｨｪ0402 0809, ｨｰｨ ｨｺｨｨ02 ｨｺｨ ｨｺ 07ｨｨ ﾂｨｪ04ｨｦ 0006090006ｨｰｨｨ01ｨｨ05010605ｨｨｨｪ (080809), ｨｪ02 06ｨ 05ｨ 01ｨ 06ｨｰ 070609ｨｰ0607ｨｪｨｪ06ｨｦ 06 00.07., 06ｨｪｨ ｨｬ060302ｨｰ ｨｨ04ｨｬ02ｨｪ07ｨｰｨｹ0907 09 04ｨ 09ｨｨ09ｨｨｨｬ0609ｨｰｨｨ 06ｨｰ 09ｨｰ080602ｨｪｨｨ07 ｨ 02ｨｨ05ｨｹｨｪ0401 02020702ｨｦ ｨｨ 090601020803ｨ ｨｪｨｨ07 09060104. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｪｨ ｨｨｨ 06050202 ﾂｨ 09ｨｰ06 0708ｨｨｨｬ02ｨｪ0702ｨｬ0401 09ｨｨｨｪｨｰ02ｨｰｨｨ ﾂ0209ｨｺｨｨ01 0809 0709050702ｨｰ0907 01ｨｨ07ｨ 05ｨｹｨｬｨｨｨｰ06ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪ (02030809), ｨｨｨｬ0206ｨｴｨｨｨｦ 09040906ｨｺｨｮ06 06 00.07. (ｨC 41 縺05) [33, 34]. 0905ｨ 000601ｨ 0807 05ｨｰ06ｨｬｨｮ 05ｨｨ07060906ｨｬ04 ｨｨ04 02030809 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ04 0708ｨｨ 0108ｨ ｨｪ02ｨｪｨｨｨｨ 09 03ｨｨ0806ｨｺ06ｨｬ 01ｨｨｨ 07ｨ 0406ｨｪ02 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08. 050609ｨｰｨ 09 ｨ 02ｨｨ05ｨｹｨｪ0401 02020702ｨｦ 0809 ｨｰｨ ｨｺ0302 ｨｬ060302ｨｰ 06ｨｺｨ 040409ｨ ｨｰｨｹ 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ0602 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ 09ｨｺ0506 ﾂ02ｨｪｨｨ02 0900 0708ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ, ｨｪｨ 0708ｨｨｨｬ0208, 09 ｨｬｨ 05ｨｹｨｰ060406ｨｦ [35]. 04070106ｨｬ ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 090407090502ｨｪ06, ﾂｨｰ06 05ｨｨ07060906ｨｬ04 09 02030809 ｨｨｨｬ0206ｨｰ ｨ 06050202 09040906ｨｺ0602 09ｨｺ0506 ﾂ02ｨｪｨｨ02 ｨｬｨ 05ｨｹｨｰ060404, ﾂ02ｨｬ 05ｨｨ07060906ｨｬ04 ｨｪｨ 0609ｨｪ060902 01ｨｨ06050206ｨｨ0500060900ｨ ｨｰｨｨ01ｨｨ05010605ｨｨｨｪｨ (02020809) [36]. 06ｨｰ06 06ｨ ｨｲ0709ｨｪ0702ｨｰ0907 0905ｨ ｨ 04ｨｬ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02ｨｬ ｨｬ020301ｨｮ ｨｬｨ 05ｨｹｨｰ060406ｨｦ ｨｨ 2 ｨｪ02ｨｪｨ 0904ｨｴ02ｨｪｨｪ04ｨｬｨｨ 03ｨｨ08ｨｪ04ｨｬｨｨ 02020707ｨｬｨｨ 02020809 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 0906 09090704ｨｹ06 ｨｬ020301ｨｮ ｨｬｨ 05ｨｹｨｰ060406ｨｦ ｨｨ ｨｪｨ 0904ｨｴ02ｨｪｨｪ04ｨｬｨｨ 02030809 ｨｨ 09ｨｬ0203ｨ ｨｪｨｪ04ｨｬｨｨ 02020707ｨｬｨｨ 080809. 01ｨ ｨｰｨｮ08ｨ 05ｨｹｨｪ0402 05ｨｨ07ｨｨ0104 ｨｪ02080201ｨｺ06 ｨｨ09070605ｨｹ04ｨｮ06ｨｰ 010507 070605ｨｮ ﾂ02ｨｪｨｨ07 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬ. 0308060202ｨｪｨｰ 09ｨｺ0506- ﾂ02ｨｪｨｨ07 ｨｮ ｨｰｨ ｨｺｨｨ01 05ｨｨ07060906ｨｬ 0908ｨ 09ｨｪｨｨｨｬ 09 09ｨｺ0506 ﾂ02ｨｪｨｨ02ｨｬ 09 05ｨｨ07060906ｨｬ04 ｨｨ04 02030809, ｨｨ 0906 ｨｬｨｪ060006ｨｬ 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ 090606ｨｰｨｪ060302ｨｪｨｨ07 0706 ｨｬｨ 090902 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608/05ｨｨ07ｨｨ01. 00 ｨｰ0201ｨｪ06050600ｨｨｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 0708ｨｨｨｬ02ｨｪ0702ｨｰ0907 ｨｰｨ ｨｺ0302 00ｨｨ0108060002ｨｪｨｨ04ｨｨ080609ｨ ｨｪｨｪ04ｨｦ 080809 (00080809), ｨｺ06ｨｰ060804ｨｦ ｨ 06050202 ｨｮ09ｨｰ06ｨｦ ﾂｨｨ09 ｨｺ 06ｨｺｨｨ090502ｨｪｨｨ06 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 ｨｪ0200ｨｨ0108060002ｨｪｨｨ04ｨｨ080609ｨ ｨｪｨｪ04ｨｬ 05ｨｨ07ｨｨ0106ｨｬ. 06ｨｺ09070208ｨｨｨｬ02ｨｪｨｰｨ 05ｨｹｨｪ06 0106ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 0708060202ｨｪｨｰ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0900 09 05ｨｨ07060906ｨｬ04 09 00080809 ｨｨ 080809 08ｨ 0902ｨｪ 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06 95 ｨｨ 85 % [37]. 0906050209ｨｰ0208ｨｨｨｪ 0906050209ｨｰ0208ｨｨｨｪ ﾂｨ 09ｨｰ06 09ｨｺ0506 ﾂｨ 06ｨｰ 09 090609ｨｰｨ 09 05ｨｨ07060906ｨｬ, ｨｰｨ ｨｺ ｨｺｨ ｨｺ 05ｨｰ06 0902ｨｴ0209ｨｰ0906 0907060906ｨ ｨｪ06 ｨｬ06010205ｨｨ080609ｨ ｨｰｨｹ 00ｨｨ04ｨｨｨｺ06-01ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ02 090906ｨｦ09ｨｰ09ｨ 05ｨｨ07ｨｨ01ｨｪ060006 ｨ ｨｨ09050607, 08ｨ 04ｨｮ070608070106 ﾂｨｨ09ｨ 07 00020502090602 090609ｨｰ0607ｨｪｨｨ02 05ｨｨ07ｨｨ01ｨｪ060006 ｨ ｨｨ09050607 ｨｨ05ｨｨ ｨｮ070608070106- ﾂｨｨ09ｨ 07 03ｨｨ01ｨｺ0602 090609ｨｰ0607ｨｪｨｨ02 [38, 39]. 06ｨｰ06ｨｰ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰ 05ｨｨ07060906ｨｬ ｨｰｨ ｨｺ0302 0905ｨｨ0702ｨｰ ｨｪｨ 070806ｨｪｨｨ02ｨ 02ｨｬ0609ｨｰｨｹ ｨ ｨｨ09050607 ｨｨ ｨｨ04ｨｬ02ｨｪ0702ｨｰ 06 00.07. 05ｨｨ07ｨｨ01ｨ 0708ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ [40, 41]. 0202ｨｦ09ｨｰ09ｨｨ02 0106050209ｨｰ0208ｨｨｨｪｨ 0609ｨｪ0609ｨ ｨｪ06 ｨｪｨ ｨｰ06ｨｬ, ﾂｨｰ06 ｨｺｨｨ090506080601 020006 00ｨｨ010806ｨｺ09ｨｨ05ｨｹｨｪ06ｨｦ 0008ｨｮ070704 090907040409ｨ 02ｨｰ ｨｬ02ｨｰｨｨ05ｨｹｨｪ0402 0008ｨｮ070704 010605ｨｨｨｪｨ 0809, ｨ 00ｨｨ010806ｨｺ09ｨｨ05ｨｹｨｪｨ 07 0008ｨｮ0707ｨ 0106050209ｨｰ0208ｨｨｨｪｨ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｮ02ｨｰ 09 05=02/04=02 0008ｨｮ0707ｨ ｨｬｨｨ 0809 [42, 43]. 0308ｨｨ ｨｪｨ 05ｨｨ ﾂｨｨｨｨ ｨ 0605ｨｹ03060006 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 0106050209ｨｰ0208ｨｨｨｪｨ 09 09ｨｰ08ｨｮｨｺｨｰｨｮ0802 05ｨｨ07060906ｨｬ 00ｨ 04060904ｨｦ 07020802010601 ｨｬ060302ｨｰ 06ｨｰ09ｨｮｨｰ09ｨｰ090609ｨ ｨｰｨｹ. 0206ｨ ｨ 090502ｨｪｨｨ02 0106050209ｨｰ0208ｨｨｨｪｨ ｨｰｨ ｨｺ0302 09ｨｪｨｨ03ｨ 02ｨｰ 09ｨｺ06080609ｨｰｨｹ 0904ｨｰ02ｨｺｨ ｨｪｨｨ07 0900 ｨｨ04 05ｨｨ07060906ｨｬ ｨｨ ｨｮ090205ｨｨ ﾂｨｨ09ｨ 02ｨｰ 0708060202ｨｪｨｰ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 04ｨ 09 ﾂ02ｨｰ 060905ｨ ｨ 0502ｨｪｨｨ07 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 ｨｬ020301ｨｮ ｨ 02ｨｨ05ｨｹｨｪ04ｨｬｨｨ 02020707ｨｬｨｨ 0809 ｨｨ ｨｮ09ｨｨ05ｨｨ09ｨ 02ｨｰ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 ｨｬ020301ｨｮ 09ｨ 01ｨ 0806ｨｬ ｨｨ 0809 [44, 45]. 09ｨｨ07060906ｨｬ04, ｨｪ02 090601020803ｨ ｨｴｨｨ02 0106050209ｨｰ0208ｨｨｨｪ, ｨ 06050202 0706010902080302ｨｪ04 01020008ｨ 01ｨ 02ｨｨｨｨ 0708ｨｨ 0105ｨｨｨｰ0205ｨｹｨｪ06ｨｬ 0108ｨ ｨｪ02ｨｪｨｨｨｨ 09 06ｨｰ05ｨｨ ﾂｨｨ02 06ｨｰ 05ｨｨ07060906ｨｬ 09 0106050209ｨｰ0208ｨｨｨｪ06ｨｬ [46]. 030609020801ｨｪ0609ｨｰｨｪ06 ｨｬ0601ｨｨ00ｨｨ02ｨｨ08ｨｮ06ｨｴｨｨ02 0902ｨｴ0209ｨｰ09ｨ 030609020801ｨｪ0609ｨｰｨｪ06 ｨｬ0601ｨｨ00ｨｨ02ｨｨ080609ｨ ｨｪｨｪ0402 05ｨｨ07060906ｨｬ04 06ｨ 05ｨ 01ｨ 06ｨｰ ｨｰｨ ｨｺｨｨｨｬｨｨ 0706050204ｨｪ04ｨｬｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｬｨｨ, ｨｺｨ ｨｺ 09040906ｨｺｨ 07 ｨｰ0208ｨ 070209ｨｰｨｨ ﾂ0209ｨｺｨ 07 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ, ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ0602 07080607090502ｨｪｨｨ02 0706ｨ 06 ﾂｨｪ0401 05000002ｨｺｨｰ0609, 07080601060503ｨｨｨｰ0205ｨｹｨｪ0602 ｨｪｨ 0106030102ｨｪｨｨ02 09 060800ｨ ｨｪｨｨ04ｨｬ02 [47, 48]. 00 ｨｺｨ ﾂ0209ｨｰ0902 070609020801ｨｪ0609ｨｰｨｪ06 ｨｬ0601ｨｨ00ｨｨ02ｨｨ08ｨｮ06ｨｴｨｨ01 0902ｨｴ0209ｨｰ09 ﾂｨ 09ｨｰ06 ｨｨ09070605ｨｹ04ｨｮ06ｨｰ 070605ｨｨ05ｨｰｨｨ0502ｨｪ0005ｨｨｨｺ0605ｨｨ (030601) 09 08ｨ 0405ｨｨ ﾂｨｪ06ｨｦ ｨｬ060502ｨｺｨｮ050708ｨｪ06ｨｦ ｨｬｨ 090906ｨｦ (2000, 5000 ｨｨ 0108.) [49]. 050609ｨｬ0209ｨｰｨｨｨｬ0609ｨｰｨｹ ｨｬ020301ｨｮ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ060806ｨｬ ｨｨ 030601 ｨｬ060302ｨｰ 0905ｨｨ07ｨｰｨｹ ｨｪｨ 070806ｨｰ02ｨｺｨｰｨｨ09ｨｪ04ｨｦ 05000002ｨｺｨｰ 09 06ｨｰｨｪ060302ｨｪｨｨｨｨ 05ｨｨ07060906ｨｬ. 00ｨｪ0600ｨｨ02 09ｨ 01ｨ 08ｨ 0709050706ｨｰ0907 05000002ｨｺｨｰｨｨ09ｨｪ04ｨｬｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｬｨｨ 010507 070200ｨｨ05ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬ, ｨｪ06, ｨｪｨ 0708ｨｨｨｬ0208, 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 0102ｨｺ09ｨｰ- 09ｨｨｨｬｨｨｨｺ06-00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ 03ｨｮ08ｨｪｨ 05. 0606ｨｬ 46, 01 4, 2012 31
1308ｨ ｨｪ06ｨｬ, ｨｨｨｪｨｮ05ｨｨｨｪ 05ｨｮ ﾂ0302 04ｨ ｨｴｨｨｨｴｨ 02ｨｰ 070200ｨｨ05ｨｨ080609ｨ ｨｪｨｪ0402 05ｨｨ07060906ｨｬ04. 06ｨｰ06 06ｨ ｨｲ0709ｨｪ0702ｨｰ0907 090609ｨｬ0209ｨｰｨｨｨｬ0609ｨｰｨｹ06 030601 09 ｨｨｨｪｨｮ05ｨｨｨｪ06ｨｬ, ｨｨ ｨｪ02090609ｨｬ0209ｨｰｨｨｨｬ0609ｨｰｨｹ06 020006 09 0102ｨｺ09ｨｰ08ｨ ｨｪ06ｨｬ [50, 51]. 020507 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 09 05ｨｨ0406ｨｬｨｮ09ｨｰｨｨｨｪ06ｨｬ ｨｪｨ 0609ｨｪ060902 050202ｨｨｨｰｨｨｨｪｨ, 0106050209ｨｰ0208ｨｨｨｪｨ, ｨｺｨ 0801ｨｨ0605ｨｨ07ｨｨｨｪｨ ｨｨ09070605ｨｹ040609ｨ 05ｨｨ 09 ｨｺｨ ﾂ0209ｨｰ0902 070609020801ｨｪ0609ｨｰｨｪ06 ｨｬ0601ｨｨ00ｨｨ02ｨｨ08ｨｮ06ｨｴｨｨ01 0902ｨｴ0209ｨｰ09 030601-2000 ｨｨ 030601-5000 09 08ｨ 0405ｨｨ ﾂｨｪ0401 090606ｨｰｨｪ060302ｨｪｨｨ0701. 020507 0904ｨ 0608ｨ 090609ｨｰｨ 09ｨ ｨ 0405ｨｨ 060202ｨｪ02ｨｪ04 09080201ｨｪｨｨｨｦ 01ｨｨｨ ｨｬ02ｨｰ08 090204ｨｨｨｺｨｮ05 ｨｨ 0708060202ｨｪｨｰ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰｨ. 09ｨｨ07060906ｨｬ04 09 030601-5000 ｨｨｨｬ0205ｨｨ 01ｨｨｨ ｨｬ02ｨｰ08 155 1 7 23 ｨｪｨｬ, 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 05ｨｨ0406ｨｬｨｮ09ｨｰｨｨｨｪｨ 090609ｨｰｨ 09ｨｨ05ｨ 90,32 1 7 0,18 %, ｨ 09 030601-2000 08ｨ 04ｨｬ0208 090204ｨｨｨｺｨｮ05 090609ｨｰｨ 09ｨｨ05 105 1 7 30 ｨｪｨｬ, 09ｨｺ0506 ﾂ02ｨｪｨｨ02 ｨ 040506 ｨｪｨ ｨｮ080609ｨｪ02 78,71 1 7 0,15 %. 030605ｨｰ06ｨｬｨｮ 010507 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 09 05ｨｨ0406ｨｬｨｮ09ｨｰｨｨｨｪ06ｨｬ 0904ｨ 08ｨ ｨｪ 090609ｨｰｨ 09, 090601020803ｨ ｨｴｨｨｨｦ 030601-5000, 06ｨ 05ｨ 01ｨ 06ｨｴｨｨｨｦ 0708ｨｨ02ｨｬ0502ｨｬ04ｨｬ 08ｨ 04ｨｬ020806ｨｬ 05ｨｨ07060906ｨｬ ｨｨ 09040906ｨｺｨｨｨｬ 0708060202ｨｪｨｰ06ｨｬ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 [31]. 00 ｨ ｨｨ0600ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨ01 ｨｨ09090502010609ｨ ｨｪｨｨ0701 ｨｪｨ ｨｬ0403ｨ 01 09 0502ｨｦｨｺ060406ｨｬ L-1210 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 05ｨｨ0406ｨｬｨｮ09ｨｰｨｨｨｪ 09 090908, 090601020803ｨ ｨｴ02ｨｦ 030601-5000, 06ｨ 05ｨ 01ｨ 05 ｨ 0605ｨｹ0302ｨｦ 03ｨｨ0806ｨｰ06ｨｦ ｨｰ0208ｨ 070209ｨｰｨｨ ﾂ0209ｨｺ060006 0102ｨｦ09ｨｰ09ｨｨ07 ｨｨ 09 010604ｨ 01 06ｨｰ 126 0106 225 ｨｬ00/ｨｺ00 0904040409ｨ 05 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｨ 04ｨｪｨ ﾂｨｨｨｬ0602 100 % ｨｨ040502 ﾂ02ｨｪｨｨ02 03ｨｨ0906ｨｰｨｪ0401 ｨ 0204 07080607090502ｨｪｨｨ07 ｨｰ06ｨｺ09ｨｨ ﾂｨｪ0609ｨｰｨｨ. 00 ｨｰ06 090802ｨｬ07 ｨｺｨ ｨｺ 0708ｨｨ 0909020102ｨｪｨｨｨｨ 090908 09 030601-2000 ｨｨ040502 ﾂ02ｨｪｨｨ02 100 % 03ｨｨ0906ｨｰｨｪ0401 ｨｪｨ ｨ 050601ｨ 050609ｨｹ 05ｨｨ03ｨｹ 09 01060402 175 ｨｬ00/ｨｺ00, ｨ 06050202 09040906ｨｺｨｨ02 01060404 06ｨｺｨ 04ｨ 05ｨｨ09ｨｹ ｨｰ06ｨｺ09ｨｨ ﾂｨｪ04ｨｬｨｨ [30]. 04ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ 0308ｨｨ 09060401ｨ ｨｪｨｨｨｨ 05ｨｨ07060906ｨｬ 0601ｨｪｨｨｨｬ ｨｨ04 09ｨ 03ｨｪ0401 05ｨｰｨ 070609 ｨｰ0201ｨｪ06050600ｨｨ ﾂ0209ｨｺ060006 07080602020909ｨ 0709050702ｨｰ0907 ｨｨ04ｨｬ0205ｨｹ ﾂ02ｨｪｨｨ02, ｨｺ06ｨｰ06080602 0609ｨｮｨｴ0209ｨｰ09050706ｨｰ 07ｨｮｨｰ02ｨｬ 0006ｨｬ060002ｨｪｨｨ04ｨ 02ｨｨｨｨ, 060409ｨｮ ﾂｨｨ09ｨ ｨｪｨｨ07, 05ｨｺ09ｨｰ08ｨｮ04ｨｨｨｨ ﾂ02080204 070605ｨｨｨｺｨ 08ｨ 06ｨｪｨ ｨｰｨｪ0402 00ｨｨ05ｨｹｨｰ0804 0708ｨｨ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0802 09040302 06 00.07. 05ｨｨ07ｨｨ01ｨ [52, 53]. 04ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ 0706090502 ｨｨ04ｨｬ0205ｨｹ ﾂ02ｨｪｨｨ07 ｨｬ060302ｨｰ 0905ｨｨ07ｨｰｨｹ ｨｪｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰｨｨ09ｨｪ04ｨｦ 05000002ｨｺｨｰ, ｨｰｨ ｨｺ ｨｺｨ ｨｺ 0708ｨｨ 010609ｨｰｨｨ0302ｨｪｨｨｨｨ 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ06ｨｦ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 00ｨ 040609060006 07020802010601ｨ 0906 090802ｨｬ07 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 09ｨｺ06080609ｨｰｨｹ 0904ｨｰ02ｨｺｨ ｨｪｨｨ07 ｨｨｨｪｨｺｨ 0709ｨｮ05ｨｨ080609ｨ ｨｪｨｪ060006 09 05ｨｨ07060906ｨｬ04 0900 ｨｺ0608080205ｨｨ08ｨｮ02ｨｰ 09 08ｨ 04ｨｬ020806ｨｬ 090204ｨｨｨｺｨｮ05. 0808ｨｨ06070806ｨｰ02ｨｺｨｰｨｨ09ｨｪ04ｨｦ 05000002ｨｺｨｰ ｨｬ060302ｨｰ 04ｨ 09ｨｨ0902ｨｰｨｹ 06ｨｰ 08ｨ 04ｨｬ0208ｨ 05ｨｨ07060906ｨｬ, ｨｪｨ 0708ｨｨｨｬ0208, 0708ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 0906 09080201ｨｪｨｨｨｬ 01ｨｨｨ ｨｬ02ｨｰ0806ｨｬ 100 ｨｪｨｬ ｨｰ080200ｨ 050604ｨ ｨｨ 09ｨ 01ｨ 080604ｨ 0706ｨｺｨ 040409ｨ 06ｨｰ 0601ｨｨｨｪｨ ｨｺ0609ｨｮ06 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ, ｨ 0708ｨｨ 09080201ｨｪ02ｨｬ 01ｨｨｨ ｨｬ02ｨｰ0802 090204ｨｨｨｺｨｮ05 25 ｨｪｨｬ ｨｪｨ ｨｨｨ 06050202 05000002ｨｺｨｰｨｨ09ｨｪｨ ｨｰ080200ｨ 050604ｨ 04ｨ 09 ﾂ02ｨｰ 000608ｨｬｨｨ080609ｨ ｨｪｨｨ07 00ｨｨ0108ｨ ｨｰｨｪ0401 000608ｨｬ, ｨｨ040605ｨｨ08ｨｮ06ｨｴｨｨ01 090601ｨｮ ｨｨ ｨｰ02ｨｬ 09ｨ ｨｬ04ｨｬ 06ｨ 02090702 ﾂｨｨ09ｨ 06ｨｴｨｨ01 09060108ｨ ｨｪ02ｨｪｨｨ02 09040906ｨｺ06ｨｦ 06 ｨｬ. 000204ｨｨｨｺｨｮ0504 09 08ｨ 04ｨｬ020806ｨｬ 06ｨｺ060506 100 ｨｪｨｬ 06ｨ 02090702 ﾂｨｨ09ｨ 06ｨｰ ｨｬ02ｨｪｨｹ03ｨｮ06 09ｨｺ06080609ｨｰｨｹ 0904ｨｰ02ｨｺｨ ｨｪｨｨ07, ﾂ02ｨｬ 090204ｨｨｨｺｨｮ0504 09 08ｨ 04ｨｬ020806ｨｬ 20 ｨC 80 ｨｪｨｬ, ﾂｨｰ06 09090704ｨ ｨｪ06 09 09040906ｨｺ06ｨｦ ｨｺ08ｨｨ09ｨｨ04ｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ04 ｨｨ 01020002ｨｺｨｰｨ ｨｬｨｨ ｨ ｨｨ09050607 06 ﾂ02ｨｪｨｹ ｨｬ0205ｨｺｨｨ01 05ｨｨ07060906ｨｬ [32]. 06ｨ ｨｺ0302 04ｨ ｨｬ02 ﾂ02ｨｪ06, ﾂｨｰ06 ｨｬｨｮ05ｨｹｨｰｨｨ05ｨ ｨｬ0205050708ｨｪ0402 090204ｨｨｨｺｨｮ0504 0906 09080201ｨｪｨｨｨｬ 01ｨｨｨ ｨｬ02ｨｰ0806ｨｬ 0106 250 ｨｪｨｬ ｨｨｨｬ0206ｨｰ ｨ 06050202 ｨｪｨｨ04ｨｺｨｮ06 09ｨｺ06080609ｨｰｨｹ 0904ｨｰ02ｨｺｨ ｨｪｨｨ07 09ｨｪｨｮｨｰ0802ｨｪｨｪ020006 090601020803ｨｨｨｬ060006 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 090204ｨｨｨｺｨｮ05ｨ ｨｬｨｨ, ｨｨｨｬ0206ｨｴｨｨｨｬｨｨ 08ｨ 04ｨｬ0208 100 ｨｪｨｬ [54]. 050502010609ｨ ｨｰ0205ｨｹｨｪ06, ｨｬ0603ｨｪ06 09010205ｨ ｨｰｨｹ 0904090601 06 ｨ 0605ｨｹ0302ｨｦ 09ｨｺ0506ｨｪｨｪ0609ｨｰｨｨ ｨｺ 0904ｨｰ02ｨｺｨ ｨｪｨｨ06 0900 ｨｨ04 05ｨｨ07060906ｨｬ 0906 09080201ｨｪｨｨｨｬ 01ｨｨｨ ｨｬ02ｨｰ0806ｨｬ ｨｬ02ｨｪ0202 80 ｨｨ ｨ 06050202 250 ｨｪｨｬ. 080806ｨｬ02 ｨｰ060006, 08ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ 0906 ｨｬｨｪ060006ｨｬ 060708020102050702ｨｰ 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｰ0208ｨ 07ｨｨｨｨ 09 090908. 01ｨ 0708ｨｨｨｬ0208, 09 ｨｨ09090502010609ｨ ｨｪｨｨ0701 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ 00ｨｨ0108060006ｨ ｨｪ060006 0006ｨｰ060902ｨｪ09ｨｨｨ ｨｨ05ｨｨ04ｨ ｨｰ0608ｨ ｨｰｨｨ060902ｨｪ09ｨ ｨｪｨ ｨｺｨ 0802ｨｨｨｪ06ｨｬ02 060805ｨｨ01ｨ ｨ 040506 0607080201020502ｨｪ06, ﾂｨｰ06 ｨｪｨ ｨｨｨ 0605ｨｹ0302ｨｦ 09020502ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ06 ｨｨ ｨｮ080609ｨｪ02ｨｬ ｨｪｨ ｨｺ06070502ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰｨ 09 ｨｺｨ 0802ｨｨｨｪ06ｨｬ02 060805ｨｨ01ｨ 06ｨ 05ｨ 01ｨ 06ｨｰ 05ｨｨ07060906ｨｬ04 09 08ｨ 04ｨｬ020806ｨｬ 06ｨｺ060506 100 ｨｪｨｬ [55]. 030605ｨｰ06ｨｬｨｮ 0708ｨｨ 08ｨ 0408ｨ ｨ 06ｨｰｨｺ02 ｨｰ0201ｨｪ06050600ｨｨｨｨ 070605ｨｮ ﾂ02ｨｪｨｨ07 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 ｨｪ0206ｨ 010601ｨｨｨｬ06 ｨｮ ﾂｨｨｨｰ0409ｨ ｨｰｨｹ, ﾂｨｰ06 09080201ｨｪｨｨｨｦ 01ｨｨｨ ｨｬ02ｨｰ08 05ｨｨ07060906ｨｬ 0706090502 080209ｨｮ090702ｨｪ01ｨｨ080609ｨ ｨｪｨｨ07 05ｨｨ0600ｨｨ04ｨ ｨｰｨ 0106050302ｨｪ ｨ 04ｨｰｨｹ ｨｪｨ ｨｮ080609ｨｪ02 100 ｨC 200 ｨｪｨｬ. 0005ｨｨ07ｨｪｨｨ02 ｨｮ09050609ｨｨｨｦ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 090601ｨｪ06ｨｦ 01ｨｨ0907020809ｨｨｨｨ ｨｪｨ ｨｺｨ ﾂ0209ｨｰ0906 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 07080207ｨ 08ｨ ｨｰｨ 05ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0609ｨｰｨｹ 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬ ｨｰｨ ｨｺ0302 060708020102050702ｨｰ0907 ｨｰｨ ｨｺｨｨｨｬｨｨ ｨｰ0201ｨｪ06050600ｨｨ ﾂ0209ｨｺｨｨｨｬｨｨ 00ｨ ｨｺｨｰ0608ｨ ｨｬｨｨ, ｨｺｨ ｨｺ 080203ｨｨｨｬ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ, ｨｰｨｨ07 0005ｨ ｨｺ06ｨｪ0609 ｨｨ 06ｨ 0608ｨｮ010609ｨ ｨｪｨｨ07 010507 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ [56]. 090608060306 07080601ｨｮｨｬｨ ｨｪｨｪｨ 07 ｨｬ02ｨｰ0601ｨｨｨｺｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 0706090403ｨ 02ｨｰ ｨｪ02 ｨｰ0605ｨｹｨｺ06 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0609ｨｰｨｹ 05ｨｨ07060906ｨｬ, ｨｪ06 ｨｨ 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 070806ｨｨ0409060109ｨｰ0902ｨｪｨｪ060006 07080602020909ｨ. 03080602020909 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬ 06ｨ 04 ﾂｨｪ06 09ｨｺ0506 ﾂｨ 02ｨｰ 3 05ｨｰｨ 07ｨ : 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 08ｨ 09ｨｰ090608ｨ 05ｨｨ07060906ｨｬ, 07020809ｨｨ ﾂｨｪｨｮ06 09ｨｮ03ｨｺｨｮ (09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ06) ｨｨ 09ｨｰ0608ｨｨ ﾂｨｪｨｮ06 09ｨｮ03ｨｺｨｮ (0102090608ｨ 02ｨｨ06). 05ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 0709050702ｨｰ0907 ｨｺ0506 ﾂ020906ｨｦ 09ｨｰｨ 01ｨｨ02ｨｦ 05ｨｰ060006 07080602020909ｨ, 060708020102050706ｨｴ02ｨｦ 000608ｨｬｨｨ080609ｨ ｨｪｨｨ02 ｨｺ08ｨｨ09ｨｰｨ 05050609 05ｨｹ01ｨ ｨｨ ｨｬ06080006050600ｨｨ06 04ｨ ｨｬ0608060302ｨｪｨｪ060006 ｨｬｨ ｨｰ0208ｨｨｨ 05ｨ. 03020809ｨｨ ﾂｨｪｨ 07 09ｨｮ03ｨｺｨ 09 0609ｨｪ0609ｨｪ06ｨｬ 0706040906050702ｨｰ ｨｮ01ｨ 05ｨｨｨｰｨｹ 090906ｨ 0601ｨｪｨｮ06 090601ｨｮ, ｨｰ060001ｨ ｨｺｨ ｨｺ 09ｨｰ0608ｨｨ ﾂｨｪｨ 07 09ｨｮ03ｨｺｨ ｪ 09090704ｨ ｨｪｨｪｨｮ06, ﾂｨｰ06 06ｨ 02090702 ﾂｨｨ09ｨ 02ｨｰ 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ02 0609ｨｰｨ ｨｰ06 ﾂｨｪ06ｨｦ 0905ｨ 00ｨｨ 09 05ｨｨ0600ｨｨ05ｨｨ04ｨ ｨｰ02 [57, 58]. 05ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 01ｨ 08ｨ ｨｺｨｰ0208ｨｨ04ｨｮ02ｨｰ0907 ｨｰｨ ｨｺｨｨｨｬｨｨ 0609ｨｪ0609ｨｪ04ｨｬｨｨ 00ｨ ｨｺｨｰ0608ｨ ｨｬｨｨ ｨｺｨ ｨｺ 09ｨｺ06080609ｨｰｨｹ ｨｨ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07, ｨ ｨｰｨ ｨｺ0302 09ｨｺ06080609ｨｰｨｹ 000608ｨｬｨｨ080609ｨ ｨｪｨｨ07 05ｨｹ01ｨ [59]. 05ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 05ｨｨ07060906ｨｬ ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ ｨ 0409ｨｰ0804ｨｬ ｨｨ ｨｬ02010502ｨｪｨｪ04ｨｬ. 090409ｨｰ080602 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 06ｨ 04 ﾂｨｪ06 0708ｨｨ090601ｨｨｨｰ ｨｺ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ06 ｨｬｨｨｨｺ08060706090802030102ｨｪｨｨｨｦ 05ｨｨ07ｨｨ01ｨｪ060006 ｨ ｨｨ09050607, ｨ 0708ｨｨ ｨｬ02010502ｨｪｨｪ06ｨｦ 09ｨｺ06080609ｨｰｨｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 090604ｨｬ0603ｨｪ06 070605ｨｮ ﾂ02ｨｪｨｨ02 ｨｺｨ ﾂ0209ｨｰ0902ｨｪｨｪ060006 07080601ｨｮｨｺｨｰｨ [56, 60]. 01ｨ 0708ｨｨｨｬ0208, 05ｨｨ07060906ｨｬ04 ｨｨ04 02030809, 04ｨ ｨｬ0608060302ｨｪｨｪ0402 ｨｬ02010502ｨｪｨｪ04ｨｬ 0907060906ｨ 06ｨｬ, ｨｨｨｬ0206ｨｰ ｨ 06050202 09040906ｨｺ0602 09ｨｺ0506 ﾂ02ｨｪｨｨ02, ﾂ02ｨｬ ｨ 0409ｨｰ0806 04ｨ ｨｬ0608060302ｨｪｨｪ0402, 0601ｨｪｨ ｨｺ06 010507 05ｨｨ07060906ｨｬ ｨｨ04 080809 08ｨ 04ｨｪｨｨ02ｨ ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪｨ. 06ｨｰ06 06ｨ ｨｲ0709ｨｪ0702ｨｰ0907 ｨｰ02ｨｬ, ﾂｨｰ06 05ｨｨ07060906ｨｬ04 ｨｨ04 02030809 ｨｨｨｬ0206ｨｰ ｨ 06050202 030209ｨｰｨｺｨｮ06 09ｨｰ08ｨｮｨｺｨｰｨｮ08ｨｮ, ﾂ02ｨｬ 05ｨｨ07060906ｨｬ04 ｨｪｨ 0609ｨｪ060902 080809 [7]. 090405ｨｨ 09040109ｨｨｨｪｨｮｨｰ04 3 00ｨｨ0706ｨｰ020404, 06ｨ ｨｲ0709ｨｪ0706ｨｴｨｨ02 09040906ｨｺｨｨｨｦ ｨｮ08060902ｨｪｨｹ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0708ｨｨ ｨｬ02010502ｨｪｨｪ06ｨｬ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨｨｨ: 0708ｨｨ 01ｨ ｨｪｨｪ06ｨｬ 09ｨｨ0102 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 ｨｬ02ｨｪｨｹ030202 ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 090204ｨｨｨｺｨｮ05 ｨｺ06ｨｪ0202ｨｪｨｰ08ｨｨ08ｨｮ02ｨｰ0907 ｨｪｨ 0008ｨ ｨｪｨｨ0202 ｨｬｨ ｨｰ08ｨｨ02ｨ ｪ 050201 ｨｨ ｨ 0605ｨｹ030202 ﾂｨｨ090506 ｪ0909ｨ ｨｬ06ｨｦ ｨｬｨ ｨｰ08ｨｨ0202 ｨｨ04 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ; 0708ｨｨ ｨｬ02010502ｨｪｨｪ06ｨｬ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨｨｨ 0102ｨｦ09ｨｰ09ｨｨ02 00ｨ ｨｺｨｰ06080609, 07060908020301ｨ 06ｨｴｨｨ01 ｨ ｨｨ090506ｨｦ, 09ｨｪｨｨ0302ｨｪ06; ｨｬ02010502ｨｪｨｪ0602 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ02 01ｨ 02ｨｰ 090604ｨｬ0603ｨｪ0609ｨｰｨｹ ｨ 01ｨ 07ｨｰｨｨ080609ｨ ｨｰｨｹ0907 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｬ02ｨｬｨ 08ｨ ｨｪ02 ｨｺ ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07ｨｬ 0609ｨｬ06ｨｰｨｨ- ﾂ0209ｨｺ060006 01ｨ 090502ｨｪｨｨ07 ｨｨ ｨｬ0201ｨ ｨｪｨｨ ﾂ0209ｨｺｨｨ01 09ｨｨ05 [35]. 0002010502ｨｪｨｪ0602 060105ｨ 030102ｨｪｨｨ02 (0,5 紊/ｨｬｨｨｨｪ) 09 0708ｨｨ09ｨｮｨｰ09ｨｰ09ｨｨｨｨ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ 06ｨ 02090702 ﾂｨｨ09ｨ 02ｨｰ ｨ 06050202 09040906ｨｺｨｨｨｦ ｨｮ08060902ｨｪｨｹ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0900 (ｨｪｨ 0708ｨｨｨｬ0208, 0906010608ｨ 09ｨｰ090608ｨｨｨｬ060006 ｨｺｨ 08ｨ 06ｨｺ09ｨｨ000506060802090202ｨｨｨｪｨ ) 09 05ｨｨ07060906ｨｬｨ 01 0706090502 05ｨｨ0600ｨｨ05ｨｹｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ ｨｨ 080200ｨｨ0108ｨ ｨｰｨ 02ｨｨｨｨ, ﾂ02ｨｬ 0706090502 ｨ 0409ｨｰ08060006 060105ｨ 030102ｨｪｨｨ07 06ｨ 08ｨ 04020609 07ｨｮｨｰ02ｨｬ 0706ｨｬ02ｨｴ02ｨｪｨｨ07 ｨｨ01 09 03ｨｨ01ｨｺｨｨｨｦ ｨ 0406ｨｰ [7]. 32 09ｨｨｨｬｨｨｨｺ06-00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ 03ｨｮ08ｨｪｨ 05. 0606ｨｬ 46, 01 4, 2012
13030605ｨｰ06ｨｬｨｮ 0708ｨｨ 070806ｨｨ0409060109ｨｰ0902 ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ09ｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 070802ｨｨｨｬｨｮｨｴ0209ｨｰ0902ｨｪｨｪ06 0708ｨｨｨｬ02ｨｪ0706ｨｰ ｨｬ02ｨｰ0601ｨｨｨｺｨｮ ｨｬ02010502ｨｪｨｪ060006 060105ｨ 030102ｨｪｨｨ07, 0706040906050706ｨｴｨｮ06 09060108ｨ ｨｪｨｨｨｰｨｹ 09040906ｨｺｨｨｨｦ ｨｮ08060902ｨｪｨｹ 09ｨｺ0506 ﾂ02ｨｪｨｨ07 0900 ｨｨ 0702080906ｨｪｨ ﾂｨ 05ｨｹｨｪ04ｨｦ 08ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ. 020507 070605ｨｮ ﾂ02ｨｪｨｨ07 05ｨｨ0600ｨｨ05ｨｨ04ｨ ｨｰｨ 09 04ｨ 01ｨ ｨｪｨｪ06ｨｦ 070608ｨｨ09ｨｰ0609ｨｰｨｹ06 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 01060503ｨｪｨ ｨ 04ｨｰｨｹ ｨｪｨｨ0302 06 ｨｬ ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ ｨｪｨ 10 紊. 05ｨｪｨ ﾂ02ｨｪｨｨ07 05ｨｰ06ｨｦ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 09090704ｨ ｨｪ04 09 09ｨｺ0506 ﾂ02ｨｪｨｨ02ｨｬ 0900 09 05ｨｨ07060906ｨｬ04 0706090502 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ. 01ｨ 0708ｨｨｨｬ0208, 09ｨｺ0506 ﾂ02ｨｪｨｨ02 07080207ｨ 08ｨ ｨｰｨ 09 05ｨｨ07060906ｨｬ04 09 02030809 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 02ｨｰ0907 06ｨｰ 0 0106 ｨC 40 紊 ｨｨ ｨｮｨｬ02ｨｪｨｹ03ｨ 02ｨｰ0907 0708ｨｨ 010609ｨｰｨｨ0302ｨｪｨｨｨｨ ｨC 45 紊 [61]. 040203ｨｨｨｬ 05ｨｨ0600ｨｨ05ｨｹｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 00 ｨｪｨ 09ｨｰ0607ｨｴ0202 090802ｨｬ07 ｨｮ0302 09ｨｮｨｴ0209ｨｰ09ｨｮ02ｨｰ ｨｬｨｪ06030209ｨｰ0906 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609, ｨｺ06ｨｰ06080402 0708060305ｨｨ 0106ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨｨ02/ｨｺ05ｨｨｨｪｨｨ ﾂ0209ｨｺｨｨ02 ｨｨ090704ｨｰｨ ｨｪｨｨ07 ｨｨ 0708ｨｨｨｬ02ｨｪ0706ｨｰ0907 09 ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ06ｨｦ 0708ｨ ｨｺｨｰｨｨｨｺ02 (ｨｰｨ ｨ 05ｨｨ02ｨ ). 00 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 ｨ 0605ｨｹ03060006 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 0802ｨｺ06ｨｬ02ｨｪ010609ｨ ｨｪ04 09050201ｨｮ06ｨｴｨｨ02 080203ｨｨｨｬ04 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 000608ｨｬ: 090802ｨｬ07 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨｨｨ ｪ 06ｨｰ 90 ｨC 100 ﾂ; 090802ｨｬ07 0708020109ｨ 08ｨｨｨｰ0205ｨｹｨｪ060006 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 ｪ 06ｨｰ 48 0106 56 ﾂ; ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨ 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 06ｨｰ ｨC 50 0106 ｨC 70 紊; 070208ｨｨ0601 070609ｨｰ0607ｨｪｨｪ06ｨｦ 09ｨｺ06080609ｨｰｨｨ 09 ｨｰ02 ﾂ02ｨｪｨｨ02 40 ｨC 50 ﾂ (070601ｨｲ02ｨｬ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 07080207ｨ 08ｨ ｨｰｨ 06ｨｰ ｨC 45 0106 ｨC 25 紊); 070208ｨｨ0601 07ｨ 01ｨ 06ｨｴ02ｨｦ 09ｨｺ06080609ｨｰｨｨ 09 ｨｰ02 ﾂ02ｨｪｨｨ02 40 ｨC 50 ﾂ (ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨ 07080207ｨ 08ｨ ｨｰｨ ｨｨ04ｨｬ02ｨｪ0702ｨｰ0907 06ｨｰ ｨC 25 0106 20 紊) [62]. 0308ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 06ｨ ｨｴｨｨ01 0708ｨｨｨｪ02ｨｨ070609 0706040906050702ｨｰ 07060106ｨ 08ｨ ｨｰｨｹ ｨｨｨｪ01ｨｨ09ｨｨ01ｨｮｨ 05ｨｹｨｪ04ｨｦ 080203ｨｨｨｬ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 010507 ｨｺｨ 030106ｨｦ 090908 09 090606ｨｰ0902ｨｰ09ｨｰ09ｨｨｨｨ 09 0202 060906ｨ 02ｨｪｨｪ0609ｨｰ07ｨｬｨｨ. 01ｨ 0708ｨｨｨｬ0208, 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨ06 05ｨｨ07060906ｨｬ 0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪｨ 07080609060107ｨｰ 09 4 % 08ｨ 09ｨｰ09060806ｨｬ 09ｨ 01ｨ 08060404, 070609ｨｰ020702ｨｪｨｪ06 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ 07 070605ｨｺｨｨ 09ｨｮｨ 05ｨｨｨｬｨ 02ｨｨ06ｨｪｨｪ06ｨｦ ｨｺｨ ｨｬ020804 06ｨｰ + 20 0106 ｨC 50 紊. 0306090502 010609ｨｰｨｨ0302ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰ06ｨｬ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 ｨC 40 紊 020006 090401020803ｨｨ09ｨ 06ｨｰ 0708ｨｨ 05ｨｰ06ｨｦ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0802 09 ｨｰ02 ﾂ02ｨｪｨｨ02 3 ﾂ. 05ｨ ｨｰ02ｨｬ 070605ｨｺｨｨ 090401020803ｨｨ09ｨ 06ｨｰ 0708ｨｨ ｨC 50 紊 ｨｨ 01ｨ 090502ｨｪｨｨｨｨ 09 ｨｺｨ ｨｬ020802 (4,0 ｨC 6,0) 1 7 10 ｨC2 ｨｬ09ｨ 08 09 ｨｰ02 ﾂ02ｨｪｨｨ02 2 ﾂ ｨｨ ｨｪｨ 00080209ｨ 06ｨｰ 06ｨｰ ｨC 50 0106 + 20 紊 0906 09ｨｺ06080609ｨｰｨｹ06 6 紊/ ﾂ. 0306090502 010609ｨｰｨｨ0302ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰ06ｨｬ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 20 紊 (01ｨ 090502ｨｪｨｨ02 09 ｨｺｨ ｨｬ020802 4,0 1 7 10 ｨC2 ｨｬ09ｨ 08) 020006 090401020803ｨｨ09ｨ 06ｨｰ 0708ｨｨ 05ｨｰ06ｨｦ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0802 09 ｨｰ02 ﾂ02ｨｪｨｨ02 2 ﾂ. 0308ｨｨ ｨｰｨ ｨｺ06ｨｬ 080203ｨｨｨｬ02 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 08ｨ 04ｨｬ0208 05ｨｨ07060906ｨｬ ｨｨ 09ｨｺ0506 ﾂ02ｨｪｨｨ02 0106ｨｺ090608ｨｮｨ ｨｨ02ｨｨｨｪｨ ｨｨ04ｨｬ02ｨｪ0706ｨｰ0907 ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06, ｨ 0609ｨｰｨ ｨｰ06 ﾂｨｪｨ 07 0905ｨ 03ｨｪ0609ｨｰｨｹ ｨｪｨ 010601ｨｨｨｰ0907 ｨｪｨ ｨｮ080609ｨｪ02 1ｨC2%[27]. 0308ｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ060006 07ｨ ｨｺ05ｨｨｨｰｨ ｨｺ090205ｨ (06ｨ ｨｺ090605ｨ ) ｨｨ09070605ｨｹ04ｨｮ06ｨｰ 10,5 % 08ｨ 09ｨｰ090608 ｨｰ080200ｨ 05060404 [49]. 03080601060503ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ 09ｨｮ03ｨｺｨｨ 05ｨｰ060006 07080207ｨ 08ｨ ｨｰｨ 0906 ｨｬｨｪ060006ｨｬ 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨｪ0401 ｨｮ09050609ｨｨｨｦ. 030905ｨｨ ｨｪｨ 05ｨｰｨ 0702 04ｨ ｨｬ0608ｨ 03ｨｨ09ｨ ｨｪｨｨ07 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨ 07060506ｨｺ ｨC 40 紊 (09ｨｺ06080609ｨｰｨｹ ｪ 11 紊/ ﾂ), ｨｰ06 07080602020909 07020809ｨｨ ﾂｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ 04ｨ ｨｪｨｨｨｬｨ 02ｨｰ 95 ﾂ, ｨ 0708ｨｨ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0802 07060506ｨｺ ｨC 50 紊 (09ｨｺ06080609ｨｰｨｹ ｪ 18 紊/ｨｬｨｨｨｪ) 0105ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ 07020809ｨｨ ﾂｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ 09ｨｪｨｨ03ｨ 02ｨｰ0907 0106 87 ﾂ. 07090205ｨｨ ﾂ02ｨｪｨｨ02 ｨｰ02ｨｬ070208ｨ ｨｰｨｮ0804 ｨｪｨ 05ｨｰｨ 0702 07020809ｨｨ ﾂｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ 09 ｨC 16 0106 ｨC 5 紊 0906ｨｺ08ｨ ｨｴｨ 02ｨｰ 090802ｨｬ07 09ｨｮ03ｨｺｨｨ 0106 67 ﾂ, ﾂｨｰ06 ｨｪ02 0905ｨｨ0702ｨｰ ｨｪｨ 08ｨ 04ｨｬ0208 ｨｨ 080209ｨｮ090702ｨｪ01ｨｨ08ｨｮ02ｨｬ0609ｨｰｨｹ 05ｨｨ07060906ｨｬ. 01ｨ 05ｨｰｨ 0702 09ｨｰ0608ｨｨ ﾂｨｪ06ｨｦ 09ｨｮ03ｨｺｨｨ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨｮ 0706090403ｨ 06ｨｰ 0106 + 20 紊. 0708060902ｨｪｨｹ 0609ｨｰｨ ｨｰ06 ﾂｨｪ06ｨｦ 0905ｨ 00ｨｨ 09 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ06ｨｬ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ06ｨｬ 07ｨ ｨｺ05ｨｨｨｰｨ ｨｺ09020502 090609ｨｰｨ 09050702ｨｰ 06ｨｺ060506 1,5 %. 00 0906090802ｨｬ02ｨｪｨｪ06ｨｬ 00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺ06ｨｬ 070806ｨｨ0409060109ｨｰ0902 060906ｨ 0602 ｨｬ0209ｨｰ06 04ｨ ｨｪｨｨｨｬｨ 06ｨｰ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0402 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0402 000608ｨｬ04, ｨｺ06ｨｰ06080402 06ｨ 05ｨ 01ｨ 06ｨｰ 08070106ｨｬ 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ0401 070802ｨｨｨｬｨｮｨｴ0209ｨｰ09, ｨｪ06 ｨｪ02ｨｮ09ｨｰ06ｨｦ ﾂｨｨ0904 0708ｨｨ 0105ｨｨｨｰ0205ｨｹｨｪ06ｨｬ 0108ｨ ｨｪ02ｨｪｨｨｨｨ 09 090601ｨｪ06ｨｬ 08ｨ 09ｨｰ09060802. 020507 070605ｨｮ ﾂ02ｨｪｨｨ07 ｨｺｨ ﾂ0209ｨｰ0902ｨｪｨｪ0401 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 ﾂｨ 09ｨｰ06 ｨｨ09070605ｨｹ04ｨｮ06ｨｰ ｨｬ02ｨｰ0601 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ, 04ｨ 0802ｨｺ06ｨｬ02ｨｪ010609ｨ 0903ｨｨｨｦ 0902ｨ 07 ｨｺｨ ｨｺ ｨｪｨ 010203ｨｪ04ｨｦ 0907060906ｨ 070609040302ｨｪｨｨ07 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0609ｨｰｨｨ 05ｨｨ07060906ｨｬ. 0308ｨｨ 07080609020102ｨｪｨｨｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ ｨｪ0206ｨ 010601ｨｨｨｬ06 ｨｮ ﾂｨｨｨｰ0409ｨ ｨｰｨｹ 09ｨｰ080602ｨｪｨｨ02 ｨ ｨｨ09050607 090204ｨｨｨｺｨｮ05, ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨｮ 00ｨ 040609060006 07020802010601ｨ 05ｨｨ07ｨｨ01ｨ ｨｨ05ｨｨ 09ｨｬ0209ｨｨ 05ｨｨ07ｨｨ010609, 08ｨ 04ｨｬ020804 090204ｨｨｨｺｨｮ05 0706090502 05ｨｺ09ｨｰ08ｨｮ04ｨｨｨｨ ｨｨ 00ｨｨ05ｨｹｨｰ08ｨ 02ｨｨｨｨ, ｨｰｨｨ07 ｨｺ08ｨｨ06070806ｨｰ02ｨｺｨｰ0608ｨ. 0308ｨｨ 070601ｨ 060802 0607ｨｰｨｨｨｬｨ 05ｨｹｨｪ0401 04ｨｪｨ ﾂ02ｨｪｨｨｨｦ 05ｨｰｨｨ01 00ｨ ｨｺｨｰ06080609 ｨｬ0603ｨｪ06 06ｨ 02090702 ﾂｨｨｨｰｨｹ 070605ｨｮ ﾂ02ｨｪｨｨ02 05000002ｨｺｨｰｨｨ09ｨｪ0401 ｨｨ 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ0401 0708ｨｨ 0108ｨ ｨｪ02ｨｪｨｨｨｨ 05ｨｨ0600ｨｨ05ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0401 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 000608ｨｬ. 00 04ｨ ｨｺ0506 ﾂ02ｨｪｨｨ02 ｨｪ0206ｨ 010601ｨｨｨｬ06 06ｨｰｨｬ02ｨｰｨｨｨｰｨｹ, ﾂｨｰ06 08ｨ 0408ｨ ｨ 06ｨｰｨｺｨ, 070806ｨｨ0409060109ｨｰ0906 ｨｨ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺ0602 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 ｨ ｨｮ0102ｨｰ ｨｮ090205ｨｨ ﾂｨｨ09ｨ ｨｰｨｹ0907 09 ｨｺｨ 030104ｨｬ 00060106ｨｬ. 030802ｨｨｨｬｨｮｨｴ0209ｨｰ09ｨ 05ｨｨ07060906ｨｬｨ 05ｨｹｨｪ0401 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 000608ｨｬ ｨｨ ｨｨ01 070208090702ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 010507 ｨｬ0201ｨｨ02ｨｨｨｪ04 ｨｪ02 0904040409ｨ 06ｨｰ 0906ｨｬｨｪ02ｨｪｨｨｨｦ. 020507 070806ｨｨ0409060109ｨｰ09ｨ 05ｨｰ06ｨｦ ｨｪ060906ｨｦ 0008ｨｮ070704 07080207ｨ 08ｨ ｨｰ0609 ｨｰ0802ｨ ｨｮ02ｨｰ0907 0906090802ｨｬ02ｨｪｨｪ0602 09040906ｨｺ06070806ｨｨ04090601ｨｨｨｰ0205ｨｹｨｪ0602 06ｨ 0608ｨｮ010609ｨ ｨｪｨｨ02, 08ｨ 0909 ﾂｨｨｨｰｨ ｨｪｨｪ0602 ｨｪｨ ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02 070208020106090401 ｨｰ0201ｨｪ06050600ｨｨｨｦ. 09060603040806070408 1. 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Pharm., 22, 299 ｨC 310 (1984). 55. 02. 01. 01ｨｮ080209ｨｨ ﾂ, 06. 01. 000202080609ｨｨ ﾂ, 01. 08. 000202080609ｨｨ ﾂ ｨｨ 0108., 040609. ｨ ｨｨ06ｨｰ0208. 03., 2, 45 ｨC 49 (2007). 56. A. Hottot, S. Vessot, and J. Andrieu, Chem. Eng. Proces., 46(7), 666 ｨC 674 (2007). 57. T. Arakawa, S. J. Prestrelski, W. C. Kenney, and J. F. Carpenter, Adv. Drug Deliv., 46, 307 ｨC 326 (2001). 58. S. Zhai, R. Taylor, R. Sanches, and N. K. H. Slater, Chem. Eng. Sci., 58(11), 2313 ｨC 2323 (2003). 59. M. K. Lee, M. Y. Kim, S. Kim, and J. Lee, J. Pharm. Sci., 98(12), 4808 ｨC 4817 (2009). 60. S. A. Velardi and A. A. Barresi, Chem. Eng. Res. Design, 86(1), 9 ｨC 22 (2008). 61. L. F. Siow, T. Rades, and M. H. Lim, Cryobiology, 55, 210 ｨC 221 (2007). 62. 07. 00. 0808ｨ 09ｨｪ06070605ｨｹ09ｨｺｨｨｨｦ, 08. 03. 05ｨｰ0207ｨ ｨｪ0609, 00. 06. 01090202, 09ｨｨ0600ｨ 08ｨｬ. 03., 3, 18 ｨC 29 (2009). 030609ｨｰｨｮ07ｨｨ05ｨ 27.05.11 SPECIFIC FEATURES OF LYOPHILIZATION OF LIPOSOMAL DRUG FORMS (A REVIEW) O. Yu. Arshinova, E. V. Sanarova, A. V. Lantsova, and N. A. Oborotova Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia Lyophilization is a promising approach to ensuring long-term stability of liposomes. After decades of studies in this field, various lyoprotective mechanisms such as water replacement and vitrification models have been proposed. Much progress has been made in obtaining highly stable liposomes after lyophilization based on the optimization of formulation and process parameters. This paper reviews cryoprotective mechanisms, their parameters affecting the cryoprotective effect, and techniques used in a large number of studies. The parameters are discussed with regard to two aspects, namely (i) formulation factors (choice of the lipid bilayer composition, vesicle size, selection of cryoprotectors, dry mass ratio of cryoprotector to lipid, distribution of cryoprotector on both sides of lipid bilayer) and (ii) technological factors (freezing protocols, drying protocols, etc.). Key words: Lyophilization, liposomes, cryoprotector, formulation 34 09ｨｨｨｬｨｨｨｺ06-00ｨ 08ｨｬｨ 020209ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ 03ｨｮ08ｨｪｨ 05. 0606ｨｬ 46, 01 4, 2012