13000209ｨｰｨｪｨｨｨｺ 020002 040801. 2006. 01 2 00.01.05030404010601, 01.08.080701010304020008 0308ｨｨ080601ｨｪ0402 0605ｨｨ0006ｨｬ0208ｨｪ0402 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 ｨC 070208090702ｨｺｨｰｨｨ09ｨｪ0402 080200ｨｮ0507ｨｰ060804 ｨｬ02ｨｰｨ ｨ 0605ｨｨ ﾂ0209ｨｺｨｨ01 ｨｪｨ 08ｨｮ0302ｨｪｨｨｨｦ 00 06ｨ 04060802 06ｨ 09ｨｮ0301ｨ 06ｨｰ0907 05ｨｨｨｰ0208ｨ ｨｰｨｮ08ｨｪ0402 ｨｨ 0906ｨ 09ｨｰ0902ｨｪｨｪ0402 01ｨ ｨｪｨｪ0402 0706 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨC 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ0401 070605ｨｨ0002ｨｪ0605ｨｹｨｪ0401 0005ｨ 0906ｨｪ06ｨｨ010609, 0708ｨｨ09ｨｮｨｰ09ｨｰ09ｨｮ06ｨｴｨｨ01 09 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06ｨｬ ｨｺ0605ｨｨ ﾂ0209ｨｰ0902 09 060906ｨｴｨ 01, 07000601ｨ 01, 0008ｨｮｨｺｨｰｨ 01 ｨｨ 06080201ｨ 01. 020906ｨ 060006 09ｨｪｨｨｨｬｨ ｨｪｨｨ07 04ｨ 0905ｨｮ03ｨｨ09ｨ 06ｨｰ 0706050603ｨｨｨｰ0205ｨｹｨｪ0602 0906040102ｨｦ09ｨｰ09ｨｨ02 ｨｪｨ ｨｨｨｬｨｬｨｮｨｪｨｪｨｮ06 ｨｨ 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰｨｮ06 09ｨｨ09ｨｰ02ｨｬ04, 0907060906ｨ ｨｪ0609ｨｰｨｹ 09ｨｪｨｨ03ｨ ｨｰｨｹ ｨｰ06ｨｺ09ｨｨ ﾂ0209ｨｺ0602 0102ｨｦ09ｨｰ09ｨｨ02 ｨ 05ｨｺ0600060507 ｨｪｨ 060800ｨ ｨｪｨｨ04ｨｬ. Oligomeric proanthocyanidin complexes as perspective regulators of metabolic disturbances at alcohol abuse. V.G.SPRYGIN, N.F.KUSHNEROVA (V.I.Il ｯichev Pacific Oceanological Institute, FEB RAS, Vladivostok). Data from publications and own data on biological activity of Olygomeric Proanthocyanidin Complexes, which are complex polyphenol polymers of flavonoid nature, have been discussed in the review. Olygomeric Proanthocyanidins are available in vegetables, berries, fruits and nuts in considerable amounts. OPC possess a broad spectrum of biological activity, and in particular they reduce toxic influence of alcohol on a human organism. 060401ｨ 09ｨｪｨ 09ｨｮｨｴ0209ｨｰ090609ｨ 0506 0708020109ｨｰｨ 090502ｨｪｨｨ02, ﾂｨｰ06 020905ｨｨ 0708ｨｨ080601ｨ 09060401ｨ 05ｨ 0701, ｨｰ06 06ｨｪｨ ｨｨｨｬ0202ｨｰ ｨｺ ｨｪ02ｨｬｨｮ ｨｨ 070806ｨｰｨｨ09060701ｨｨ02, ｨｪｨｮ03ｨｪ06 ｨｰ0605ｨｹｨｺ06 020006 ｨｪｨ ｨｦｨｰｨｨ. 07 ﾂ02ｨｪ0402 06ｨ 08ｨ ｨｰｨｨ05ｨｨ 09ｨｪｨｨｨｬｨ ｨｪｨｨ02, ﾂｨｰ06 09 08ｨ ｨｦ06ｨｪｨ 01 09 070802ｨｨｨｬｨｮｨｴ0209ｨｰ0902ｨｪｨｪ04ｨｬ 0706ｨｰ0802ｨ 0502ｨｪｨｨ02ｨｬ ｨｪｨ ｨｰｨｮ08ｨ 05ｨｹｨｪ0401 0907ｨｨ08ｨｰ090601020803ｨ ｨｴｨｨ01 ｨｪｨ 07ｨｨｨｰｨｺ0609 (0808ｨ ｨｪ02ｨｨ07, 06ｨｰｨ 05ｨｨ07, 060907ｨ ｨｪｨｨ07 ｨｨ ｨｰ.01.), ｨｰｨ ｨｺｨｨ01 ｨｺｨ ｨｺ ｨｪｨ ｨｰｨｮ08ｨ 05ｨｹｨｪ0602 09ｨｨｨｪ060008ｨ 01ｨｪ0602 09ｨｨｨｪ06, 07ｨ 0506 ﾂｨｪ04ｨｦ 09ｨｨ0108, ｨｪｨ 0601ｨｪ060006 ﾂ0205060902ｨｺｨ 09 09080201ｨｪ02ｨｬ 0708ｨｨ010601ｨｨｨｰ0907 ｨ 05ｨｺ0600060507 ｨ 0605ｨｹ0302, ﾂ02ｨｬ 09 08ｨ ｨｦ06ｨｪｨ 01 070802ｨｨｨｬｨｮｨｴ0209ｨｰ0902ｨｪｨｪ060006 0706ｨｰ0802ｨ 0502ｨｪｨｨ07 090601ｨｺｨｨ ｨｨ 0108ｨｮ00ｨｨ01 ｨｺ080207ｨｺｨｨ01 ｨｪｨ 07ｨｨｨｰｨｺ0609, 090601020803ｨ ｨｴｨｨ01 ｨｰ0605ｨｹｨｺ06 01ｨｨ09ｨｰｨｨ0505ｨｨ080609ｨ ｨｪｨｪ04ｨｦ ｨ 05ｨｺ06000605ｨｹ. 0201ｨｪｨ ｨｺ06 0009ｨｨｨｪｨｪ040203 ｨｪｨ 08060104 ｨｬ02ｨｪ0202 0706010902080302ｨｪ04 ｨ 05ｨｺ06000605ｨｨ04ｨｬｨｮ, ﾂ02ｨｬ 0009060106 ﾂｨｪ040203 [1]. 02ｨ ｨｪｨｪ04ｨｦ 0002ｨｪ06ｨｬ02ｨｪ, 0706-09ｨｨ01ｨｨｨｬ06ｨｬｨｮ, 06ｨ ｨｮ090506090502ｨｪ ｨｺ06ｨｬ070502ｨｺ0906ｨｬ 0902ｨｴ0209ｨｰ09, 090601020803ｨ ｨｴｨｨ010907 09 09ｨｨｨｪ060008ｨ 0102 ｨｨ 07ｨ 0506ｨｺｨ 01 ｨｨ 0907060906ｨ ｨｪ0401 0905ｨｨ07ｨｰｨｹ ｨｪｨ 0708060202090904 06ｨ ｨｬ02ｨｪｨ 05ｨｰｨ ｨｪ0605ｨ 09 060800ｨ ｨｪｨｨ04ｨｬ02, 09ｨｬ0700 ﾂｨ 07 020006 09080201ｨｪ0602 0102ｨｦ09ｨｰ09ｨｨ02 ｨｪｨ ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬ ｨｨ ｨｮ09ｨｺ06080707 0505ｨｨｨｬｨｨｨｪｨ 02ｨｨ06 ｨｰ06ｨｺ09ｨｨ ﾂ0209ｨｺｨｨ01 07080601ｨｮｨｺｨｰ0609 ｨｨ04 060800ｨ ｨｪｨｨ04ｨｬｨ. 0206ｨｬｨｨｨｪｨｨ08ｨｮ06ｨｴｨｨｨｬ ｨｺ05ｨ 090906ｨｬ ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ ｨ ｨｺｨｰｨｨ09ｨｪ0401 09060201ｨｨｨｪ02ｨｪｨｨｨｦ 09ｨｨｨｪ060008ｨ 01ｨ ｨｨ 07ｨ 0506ｨｺ, ｨ 090502010609ｨ ｨｰ0205ｨｹｨｪ06, ｨｨ ｨ 05ｨｺ06000605ｨｹｨｪ0401 ｨｪｨ 07ｨｨｨｰｨｺ0609, 070605ｨｮ ﾂｨ 02ｨｬ0401 ｨｪｨ 0609ｨｪ060902 ｨｨ01 0702080208ｨ ｨ 06ｨｰｨｺｨｨ, 0709050706ｨｰ0907 ｨｰｨ ｨｺ ｨｪｨ 040409ｨ 02ｨｬ0402 ｨｺ06ｨｬ070502ｨｺ0904 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, ｨｨ05ｨｨ ｨｺ06ｨｪ0102ｨｪ09ｨｨ080609ｨ ｨｪｨｪ0402 ｨｰｨ ｨｪｨｪｨｨｨｪ04, 0708020109ｨｰｨ 09050706ｨｴｨｨ02 0906ｨ 06ｨｦ 070605ｨｨｨｬ0208ｨｪ0402 000608ｨｬ04 0005ｨ 0906ｨｪ06ｨｨ010609 ｨｨ04 0008ｨｮ070704 ｨｺｨ ｨｰ0201ｨｨｨｪ0609. 0601 090601020803ｨ ｨｪｨｨ02 09 ｨｮｨｺｨ 04ｨ ｨｪｨｪ0401 ｨｪｨ 07ｨｨｨｰｨｺｨ 01 ｨｬ060302ｨｰ 010609ｨｰｨｨ00ｨ ｨｰｨｹ 700 ｨｬ00/05 ｨｨ ｨ 06050202 [37]. 0905ｨ 000601ｨ 0807 060906ｨ 02ｨｪｨｪ0609ｨｰ07ｨｬ 01ｨｨｨｬｨｨ ﾂ0209ｨｺ060006 09ｨｰ080602ｨｪｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0907060906ｨ ｨｪ04 090409ｨｰｨｮ07ｨ ｨｰｨｹ 09 ｨｺｨ ﾂ0209ｨｰ0902 09ｨ ｨｬ0609ｨｰ0607ｨｰ0205ｨｹｨｪ06ｨｦ 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06-09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 09ｨｨ09ｨｰ02ｨｬ04 (01ｨｨｨｪ06ｨｪｨC0902ｨｬｨｨ01ｨｨｨｪ06ｨｪｨC0002ｨｪ0605), 06ｨｺｨ 040409ｨ 07 ｨｪ0207060908020109ｨｰ0902ｨｪｨｪ0602 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ 07020802ｨｪ0609 070806ｨｰ06ｨｪ0609 ｨｨ 050502ｨｺｨｰ0806ｨｪ0609 [11] 09 07080602020909ｨ 01 06ｨ ｨｬ02ｨｪｨ 05ｨｰｨ ｨｪ0605ｨ ｨｨ 020006 ｨｪｨ ｨｨｨ 06050202 ｨｰ06ｨｺ09ｨｨ ﾂｨｪ060006 ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰｨ ｨC ｨｮｨｺ09ｨｮ09ｨｪ060006 ｨ 05ｨｹ010200ｨｨ01ｨ. 05030404010601 0005ｨ 01ｨｨｨｬｨｨ08 0102ｨｪｨｪｨ 01ｨｹ0209ｨｨ ﾂ ｨC ｨｺｨ ｨｪ01ｨｨ01ｨ ｨｰ ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ01 ｨｪｨ ｨｮｨｺ, 080701010304020008 01ｨ ｨｰｨ 05ｨｹ07 08020106080609ｨｪｨ ｨC 0106ｨｺｨｰ0608 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ01 ｨｪｨ ｨｮｨｺ (06ｨｨ010606ｨｺ02ｨ ｨｪ09ｨｺｨｨｨｦ 06ｨｺ02ｨ ｨｪ06050600ｨｨ ﾂ0209ｨｺｨｨｨｦ ｨｨｨｪ09ｨｰｨｨｨｰｨｮｨｰ ｨｨｨｬ. 00.06.0605ｨｹｨｨ ﾂ0209ｨ 020002 040801, 0005ｨ 01ｨｨ090609ｨｰ06ｨｺ). 81
130205ｨｨ0006ｨｬ0208ｨｪ0402 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 ｨC 0601ｨｪｨｨ ｨｨ04 09ｨ ｨｬ0401 ｨｨｨｪｨｰ02080209ｨｪ0401 ｨｨ 09ｨ 03ｨｪ0401 010507 ﾂ0205060902ｨｺｨ 0708020109ｨｰｨ 09ｨｨｨｰ020502ｨｦ 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ0401 070605ｨｨ0002ｨｪ0605ｨｹｨｪ0401 09060201ｨｨｨｪ02ｨｪｨｨｨｦ. 0601 070208090602 04ｨ 080200ｨｨ09ｨｰ08ｨｨ080609ｨ ｨｪｨｪ0602 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨｰ0208ｨ 070209ｨｰｨｨ ﾂ0209ｨｺ060006 0908020109ｨｰ09ｨ 06ｨｰｨｪ0609ｨｨｨｰ0907 ｨｺ 1534 00., ｨｺ060001ｨ ｨｨｨｪ0102ｨｦ0204 0706ｨｺｨ 04ｨ 05ｨｨ ｨ ｨｬ0208ｨｨｨｺｨ ｨｪ09ｨｺｨｨｨｬ 07ｨｮｨｰ02030209ｨｰ0902ｨｪｨｪｨｨｨｺｨ ｨｬ, ｨｺｨ ｨｺ 04ｨ 09ｨ 08ｨｨ09ｨ ｨｰｨｹ ｨｺ0608ｨｮ 090609ｨｪ04, ﾂｨｰ06ｨ 04 070605ｨｮ ﾂｨｨｨｰｨｹ ﾂｨ ｨｦ, 0708020106ｨｰ0908ｨ ｨｴｨ 06ｨｴｨｨｨｦ 08ｨ 0409ｨｨｨｰｨｨ02 02ｨｨｨｪ00ｨｨ [19]. 0105ｨ 09ｨｪ0602 06ｨｰ05ｨｨ ﾂｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 06ｨｰ 0609ｨｰｨ 05ｨｹｨｪ0401 070605ｨｨ0002ｨｪ0605ｨｹｨｪ0401 09060201ｨｨｨｪ02ｨｪｨｨｨｦ 09 ｨｰ06ｨｬ, ﾂｨｰ06 06ｨｪｨｨ 090609ｨｰｨ 09050706ｨｰ 0609ｨｪ0609ｨｪｨｮ06 (0106 80%) ﾂｨ 09ｨｰｨｹ 0706ｨｰ0802ｨ 050702ｨｬ0401 ﾂ0205060902ｨｺ06ｨｬ ｨ ｨｨ060005ｨ 0906ｨｪ06ｨｨ010609. 06ｨｬｨｨ ｨ 0600ｨ ｨｰ04 08ｨ 09ｨｰ02ｨｪｨｨ07, 0008ｨｮｨｺｨｰ04 ｨｨ ｨｪｨ ｨｰｨｮ08ｨ 05ｨｹｨｪ0402 ｨｪｨ 07ｨｨｨｰｨｺｨｨ, ｨｺ06ｨｰ06080402 ｨｨ09070605ｨｹ040609ｨ 05ｨｨ09ｨｹ ﾂ0205060902ｨｺ06ｨｬ 09 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ0401 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 01 09 ｨｪ0204ｨ 07ｨ ｨｬ07ｨｰｨｪ0401 090802ｨｬ02ｨｪ. 070706ｨｰ0802ｨ 0502ｨｪｨｨ02 09ｨｨｨｪｨ, ｨｪｨ 0708ｨｨｨｬ0208, ｨｪｨ 09 ﾂｨｨｨｰ0409ｨ 02ｨｰ ｨｮ0302 ｨ 06050202 6000 0502ｨｰ. 080806ｨｬ02 09ｨｨｨｪｨ 09 0907ｨｨ0906ｨｺ 07080601ｨｮｨｺｨｰ0609 07ｨｨｨｰｨ ｨｪｨｨ07, ｨ 0600ｨ ｨｰ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬｨｨ ｨｨ ｨｬ06ｨｪ06ｨｬ0208ｨｪ04ｨｬｨｨ ｨｺｨ ｨｰ0201ｨｨｨｪｨ ｨｬｨｨ, 0901060107ｨｰ 09ｨｨｨｪ060008ｨ 01, 07ｨ 0506ｨｺｨｨ, ｨ 06ｨ 04, 070302ｨｪｨｨ02ｨ, ｨ ｨｰｨ ｨｺ0302 ｨｺｨ ｨｺｨ 06, ｨｺ060002, 07ｨ 0506 ﾂｨｪ04ｨｦ 09ｨｨ0108, ﾂｨ ｨｦ 09090201 09ｨｨ010609 [37]. 05060005ｨ 09ｨｪ06 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｨｨｬ 01ｨ ｨｪｨｪ04ｨｬ, 02030201ｨｪ0209ｨｪ0602 0706ｨｰ0802ｨ 0502ｨｪｨｨ02 ｨ ｨｨ060005ｨ 0906ｨｪ06ｨｨ010609 09 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ06ｨｦ 07ｨｨｨｴ02ｨｦ 09 020908060702ｨｦ09ｨｺｨｨ01 09ｨｰ08ｨ ｨｪｨ 01 010609ｨｰｨｨ00ｨ 02ｨｰ 1,5 00 [24]. 0209ｨｪ0609ｨｪｨｮ06 ﾂｨ 09ｨｰｨｹ 06ｨｰ 05ｨｰ060006 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 090609ｨｰｨ 09050706ｨｰ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 ｨｨ ｨｨ01 ｨｬ06ｨｪ06ｨｬ0208ｨｪ0402 040902ｨｪｨｹ07 ｨC ｨｺｨ ｨｰ0201ｨｨｨｪ04 ｨｨ 0502ｨｦｨｺ06ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04, ｨｰｨ ｨｺ ｨｺｨ ｨｺ ｨｰ0605ｨｹｨｺ06 05ｨｰｨｨ 09060201ｨｨｨｪ02ｨｪｨｨ07 0005ｨ 0906ｨｪ06ｨｨ01ｨｪ06ｨｦ 0708ｨｨ08060104 0907060906ｨ ｨｪ04 06ｨ 08ｨ 0406090409ｨ ｨｰｨｹ 070605ｨｨｨｬ0208ｨｪ0402 09ｨｰ08ｨｮｨｺｨｰｨｮ0804. 00ｨ 03ｨｪ0609ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｺｨ ｨｺ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰｨ 040106080609060006 07ｨｨｨｰｨ ｨｪｨｨ07 06ｨ ｨｮ09050609ｨｨ05ｨ 090401020502ｨｪｨｨ02 06 ﾂｨｨｨｴ02ｨｪｨｪ0401 ｨｺ06ｨｬ070502ｨｺ090609 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ ｨ ｨｺｨｰｨｨ09ｨｪ0401 0106ｨ ｨ 0906ｨｺ ｨｺ 07ｨｨｨｴ02. 00 ｨｪ02ｨｺ06ｨｰ06080401 09ｨｰ08ｨ ｨｪｨ 01 09060401ｨ ｨｪ04 ｨ 01ｨｬｨｨｨｪｨｨ09ｨｰ08ｨ ｨｰｨｨ09ｨｪ0402 060800ｨ ｨｪ04, 080200ｨｮ05ｨｨ08ｨｮ06ｨｴｨｨ02 ｨｨ01 ｨｺｨ ﾂ0209ｨｰ0906 ｨｨ ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ02. 06ｨ ｨｺ, 09 050108 0802010208ｨ 05ｨｹｨｪ04ｨｦ ｨｺ06ｨｬｨｨｨｰ02ｨｰ 080200ｨｮ05ｨｨ08ｨｮ02ｨｰ ｨｺｨ ﾂ0209ｨｰ0906 070609ｨｰｨｮ07ｨ 06ｨｴ020006 ｨｪｨ 0804ｨｪ06ｨｺ 05ｨｺ09ｨｰ08ｨ ｨｺｨｰｨ ｨｨ04 09ｨｨｨｪ060008ｨ 01ｨｪ0401 ｨｺ0609ｨｰ06 ﾂ02ｨｺ. 06ｨｺ09ｨｰ08ｨ ｨｺｨｰ 0708020109ｨｰｨ 09050702ｨｰ 0906ｨ 06ｨｦ ｨｺ06ｨｬ070502ｨｺ09 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, ｨｪｨ ｨｨｨ 06050202 03ｨｨ0806ｨｺ06 0708ｨｨｨｬ02ｨｪ0702ｨｬ04ｨｦ 09 ｨｪｨ 09ｨｰ0607ｨｴ0202 090802ｨｬ07. 05 ｨｰ06 ﾂｨｺｨｨ 040802ｨｪｨｨ07 01ｨｨｨｬｨｨ ﾂ0209ｨｺ060006 09ｨｰ080602ｨｪｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0708020109ｨｰｨ 09050706ｨｰ 0906ｨ 06ｨｦ 070605ｨｨｨｬ0208ｨｪ0402 0005ｨ 09ｨ ｨｪ-3-060504, ｨｺ06ｨｰ06080402 ｨｨｨｬ0206ｨｰ ｨｰｨｨ07ｨｨ ﾂｨｪ04ｨｦ 056-053-056-0005ｨ 0906ｨｪ06ｨｨ01ｨｪ04ｨｦ 09ｨｺ020502ｨｰ. 01ｨ ｨｨｨ 06050202 03ｨｨ0806ｨｺ06 09 07ｨｨｨｴ02090401 07080601ｨｮｨｺｨｰｨ 01 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ060006 070806ｨｨ090106030102ｨｪｨｨ07 08ｨ 0907080609ｨｰ08ｨ ｨｪ02ｨｪ04 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 09 08ｨ 09070605060302ｨｪｨｨ02ｨｬ 00ｨｨ010806ｨｺ09ｨｨ05ｨｹｨｪ0401 0008ｨｮ0707 09 070605060302ｨｪｨｨｨｨ 3',4'- 09 ｨｺ0605ｨｹ0202 00 ｨｨ 070806010205ｨｹ00ｨｨｨｪｨｨ01ｨｨｨｪ04 09 3',4',5'-ｨｰ08ｨｨ00ｨｨ010806ｨｺ09ｨｨ-04ｨ ｨｬ02ｨｴ02ｨｪｨｨ02ｨｬ. 030806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 ﾂｨ 09ｨｰ06 0909ｨｰ0802 ﾂｨ 06ｨｰ0907 09 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ0401 07080601ｨｮｨｺｨｰｨ 01 ｨｨ ｨｪｨ 07ｨｨｨｰｨｺｨ 01 09 09ｨｬ0209ｨｨ 09 070806010205ｨｹ00ｨｨｨｪｨｨ01ｨｨｨｪｨ ｨｬｨｨ [37]. 030806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 09ｨｮｨｴ0209ｨｰ09ｨｮ06ｨｰ 09 09ｨｨ0102 08ｨ 09ｨｰ090608ｨｨｨｬ0401 09 09060102 000605ｨｨ0006ｨｬ0208060903, 090601020803ｨ ｨｴｨｨ01 06ｨｰ 0109ｨｮ01 0106 030209ｨｰｨｨ 00ｨｺｨ ｨｰ0201ｨｨｨｪ0609040103 0201ｨｨｨｪｨｨ02, ｨ ｨｰｨ ｨｺ0302 09 09ｨｨ0102 ｨｪ0208ｨ 09ｨｰ090608ｨｨｨｬ0401 09 09060102 00070605ｨｨｨｬ0208060903 0906 09ｨｰ020702ｨｪｨｹ06 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ 06ｨｰ 7 ｨｨ 09040302, ｨｺ06ｨｰ06080402 0708020109ｨｰｨ 09050706ｨｰ 0906ｨ 06ｨｦ 0609ｨｪ0609ｨｪｨｮ06 (0106 80%) ﾂｨ 09ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ06090401 ｨｺ06ｨｬ070502ｨｺ090609 [23]. 08ｨ ｨｰ0201ｨｨｨｪ06090402 0201ｨｨｨｪｨｨ0204 09 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ 01 09 0609ｨｪ0609ｨｪ06ｨｬ 09090704ｨ ｨｪ04 ﾂ02080204 ｨ ｨｰ06ｨｬ04 ｨｮ000502080601ｨ, ｨｪｨ 01060107ｨｴｨｨ020907 09 4-ｨｬ, 8-ｨｬ ｨｨ05ｨｨ 6-ｨｬ 070605060302ｨｪｨｨ0701 (08ｨｨ09. 1). 06ｨ ｨｺｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 06ｨｰｨｪ060907ｨｰ0907 ｨｺ ｨｰｨｨ07ｨｮ 00 (01ｨｨｨｬ020804) ｨｨ ｨｰｨｨ07ｨｮ 05 (ｨｰ08ｨｨｨｬ020804) (08ｨｨ09. 2). 07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 08 ｨｰｨｨ07ｨ ｨｬ06ｨｪ06ｨｬ0208ｨｪ0402 0201ｨｨｨｪｨｨ0204 09090704ｨ ｨｪ04 0109ｨｮｨｬ07 0909070407ｨｬｨｨ (0601ｨｪ06ｨｦ 05ｨC05 ｨｨ 0601ｨｪ06ｨｦ 05ｨC02) (08ｨｨ09. 2). 08ｨｨ04ｨｨｨｺ06-01ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ02 090906ｨｦ09ｨｰ09ｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, 06ｨ ｨｮ0905060905ｨｨ09ｨ 06ｨｴｨｨ02 ｨｨ01 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 030609ｨｺ0605ｨｹｨｺｨｮ 09 0708ｨｨ08060102 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0909ｨｰ0802 ﾂｨ 06ｨｰ0907 09 09ｨｨ0102 09ｨｬ0209ｨｨ 0605ｨｨ0006ｨｬ02080609 08ｨ 0405ｨｨ ﾂｨｪ06ｨｦ 09ｨｰ020702ｨｪｨｨ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ, ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ0906 08ｨ ｨ 06ｨｰ 0706 ｨｨ04ｨｮ ﾂ02ｨｪｨｨ06 ｨｨ01 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ in vivo ｨｨ in vitro 070806090601ｨｨ050609ｨｹ 09 07080207ｨ 08ｨ ｨｰｨ ｨｬｨｨ, 090601020803ｨ ｨｴｨｨｨｬｨｨ ｨｬ06ｨｪ06ｨｬ0208ｨｪ0402 ｨｺｨ ｨｰ0201ｨｨｨｪ04, 0605ｨｨ0006ｨｬ0208ｨｪ0402 ｨｨ 070605ｨｨｨｬ0208ｨｪ0402 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04. 02ｨ ｨｪｨ 08ｨｮ03ｨｨ09ｨ 02ｨｬ0402 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ02 05000002ｨｺｨｰ04 ｨ 0405ｨｨ 06ｨ ｨｮ090506090502ｨｪ04 0907060906ｨ ｨｪ0609ｨｰｨｹ06 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 090907040409ｨ ｨｰｨｹ ｨ 0205ｨｺｨｨ, ｨ ｨｰｨ ｨｺ0302 ｨｨ01 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ06ｨｦ, ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ06ｨｦ, ｨ ｨｪｨｰｨｨｨ ｨ ｨｺｨｰ0208ｨｨｨ 05ｨｹｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ06 [37]. 02ｨｰ ﾂｨｨ0905ｨ 0002ｨｪ0605ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨ06ｨｪｨ 05ｨｹｨｪ0401 0008ｨｮ0707 09 ｨｬ060502ｨｺｨｮ0502 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ 04ｨ 09ｨｨ0907ｨｰ ｨｰ08ｨｨ 0609ｨｪ0609ｨｪ0401 020006 090906ｨｦ09ｨｰ09ｨ : 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｰｨ ｨｪｨｪｨｨｨｪ-ｨ 0205ｨｺ06090401 ｨｺ06ｨｬ070502ｨｺ090609, 010205ｨ ｨｰｨｪ0401 09060201ｨｨｨｪ02ｨｪｨｨｨｦ 09 ｨｬ02ｨｰｨ 0505ｨ ｨｬｨｨ ｨｨ 09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ04ｨｦ 0706ｨｰ02ｨｪ02ｨｨｨ 05. 82
1304ｨｨ09. 1. 09ｨ 040609ｨ 07 09ｨｰ08ｨｮｨｺｨｰｨｮ08ｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609: R 1, R 2 =H (070806070205ｨ 080006ｨｪｨｨ01ｨｨｨｪ04); R 1 =H, R 2 =OH (07080602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04); R 1, R 2 =OH (070806010205ｨｹ00ｨｨｨｪｨｨ01ｨｨｨｪ04) [37] 0004ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 09 ｨ 0205ｨｺｨ ｨｬｨｨ. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｪｨ ｨｨｨ 06050202 ｨｨ04090209ｨｰｨｪ0401 090906ｨｦ09ｨｰ09 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｺｨ ｨｺ 09060201ｨｨｨｪ02ｨｪｨｨｨｦ, 06ｨｰｨｪ060907ｨｴｨｨ010907 ｨｺ ｨｺ05ｨ 0909ｨｮ ｨｰｨ ｨｪｨｪｨｨｨｪ0609, 0709050702ｨｰ0907 ｨｨ01 0907060906ｨ ｨｪ0609ｨｰｨｹ 090907040409ｨ ｨｰｨｹ0907 09 ｨ 0205ｨｺｨ ｨｬｨｨ. 09020506ｨｺ-070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ06090402 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 01ｨ 08ｨ ｨｺｨｰ0208ｨｨ04ｨｮ06ｨｰ0907 ｨｺｨ ｨｺ 06ｨ 08ｨ ｨｰｨｨｨｬ0402 01ｨｨｨｪｨ ｨｬｨｨ ﾂ0209ｨｺｨｨ02 070609020801ｨｪ0609ｨｰｨｪ0402 07090502ｨｪｨｨ07, 06ｨ ｨｮ090506090502ｨｪｨｪ0402 00ｨｨ0108060006ｨ ｨｪ04ｨｬ 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02ｨｬ ｨｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02ｨｬ 09060106080601ｨｪ0401 0909070402ｨｦ ｨｬ020301ｨｮ 0002ｨｪ0605ｨｹｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｨ ｨｺｨ 08ｨ 06ｨｪｨｨ05ｨｹｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ ｨ 0205ｨｺ0609 [23]. 030806 ﾂｨｪ0609ｨｰｨｹ 06ｨ 08ｨ 04ｨｮ06ｨｴｨｨ010907 0909070402ｨｦ 04ｨ 09ｨｨ09ｨｨｨｰ ｨｺｨ ｨｺ 06ｨｰ 0708ｨｨ08060104 ｨ 0205ｨｺｨ, ｨｰｨ ｨｺ ｨｨ 06ｨｰ 0708ｨｨ08060104 ｨｬ060502ｨｺｨｮ0504 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ, 09 060906ｨ 02ｨｪｨｪ0609ｨｰｨｨ 06ｨｰ 0202 ｨｬ060502ｨｺｨｮ050708ｨｪ060006 090209ｨ, 09ｨｰ020702ｨｪｨｨ 00ｨ 050506ｨｨ04ｨ 02ｨｨｨｨ ｨｨ 00ｨｨ010806ｨｺ09ｨｨ05ｨｨ080609ｨ ｨｪｨｨ07. 05 09060408ｨ 09ｨｰｨ ｨｪｨｨ02ｨｬ 07020802 ﾂｨｨ090502ｨｪｨｪ0401 07ｨ 08ｨ ｨｬ02ｨｰ080609 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 02ｨｰ0907 09ｨｰ020702ｨｪｨｹ 0908060109ｨｰ09ｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｺ ｨ 0205ｨｺｨ ｨｬ ｨｨ, 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06, 070806 ﾂｨｪ0609ｨｰｨｹ ｨ 020506ｨｺ-070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609060006 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ07 [22]. 090205ｨｺｨｨ 09 ｨｺ06ｨｬ07ｨ ｨｺｨｰｨｪ06ｨｦ 000506ｨ ｨｮ050708ｨｪ06ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ0806ｨｦ ｨｨｨｬ0206ｨｰ ｨ 06050202 ｨｪｨｨ04ｨｺ0602 0908060109ｨｰ0906 ｨｺ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬ, ﾂ02ｨｬ ｨ 0205ｨｺｨｨ 09 ｨ 0209070608070106 ﾂｨｪ06ｨｦ 0907ｨｨ08ｨ 05ｨｹｨｪ06ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ0806ｨｦ. 00 ｨｮ09050609ｨｨ0701, ｨｺ060001ｨ ｨｺ06ｨｬ07ｨ ｨｺｨｰｨｪ0402 000506ｨ ｨｮ050708ｨｪ0402 ｨ 0205ｨｺｨｨ ｨｰ02080706ｨｰ 09090606 09ｨｰ0608ｨｨ ﾂｨｪｨｮ06 ｨｨ ｨｰ0802ｨｰｨｨ ﾂｨｪｨｮ06 09ｨｰ08ｨｮｨｺｨｰｨｮ08ｨｮ, 09060408ｨ 09ｨｰｨ 02ｨｰ ｨｨ ｨｨ01 0908060109ｨｰ0906 ｨｺ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬ [22]. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｬｨ ｨｺ0806ｨｬ060502ｨｺｨｮ05ｨ ｨｬｨｨ 09 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ 09ｨｨ09ｨｰ02ｨｬ02 ｨｬ060302ｨｰ 0708ｨｨ090601ｨｨｨｰｨｹ ｨｺ ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ06 0202 00ｨｨ04ｨｨｨｺ06-01ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ01 01ｨ 08ｨ ｨｺｨｰ0208ｨｨ09ｨｰｨｨｨｺ, 06ｨｺｨ 040409ｨ 07 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ 09ｨｨ09ｨｰ02ｨｬｨｮ 09 02020506ｨｬ. 06ｨｬ02ｨｪｨｪ06 0907060906ｨ ｨｪ0609ｨｰｨｹ 06ｨ 08ｨ 0406090409ｨ ｨｰｨｹ ｨｰｨ ｨｪｨｪｨｨｨｪ-ｨ 0205ｨｺ06090402 09090704ｨｨ, ｨｪｨ 080701ｨｮ 09 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06-09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 090906ｨｦ09ｨｰ09ｨ ｨｬｨｨ, 06ｨ ｨｮ0905060905ｨｨ09ｨ 02ｨｰ ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ06ｨｴ0202 0102ｨｦ09ｨｰ09ｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ ｨｺ09ｨ ｨｪｨｰｨｨｨｪ06ｨｺ09ｨｨ01ｨ 04ｨｮ, ｨｺ060505ｨ 0002ｨｪｨ 04ｨｮ, ｨ 02ｨｰｨ -000506ｨｺｨｮ0806ｨｪｨｨ01ｨ 04ｨｮ ｨｨ 00ｨｨｨ 05ｨｮ0806ｨｪｨｨ01ｨ 04ｨｮ [27], ｨｺ06ｨｰ06080402 09 ﾂｨｨｨｰｨ 06ｨｰ0907 ｨｺ0506 ﾂ020904ｨｬｨｨ 000208ｨｬ02ｨｪｨｰｨ ｨｬｨｨ ｨｬ02ｨｰｨ ｨ 0605ｨｨ ﾂ0209ｨｺｨｨ01 ｨｺｨ 09ｨｺｨ 010609 ｨｺｨ 07ｨｨ05050708ｨｪ060006 05ｨｪ0106ｨｰ0205ｨｨ07 [26] ｨｨ 09ｨｪ02090609ｨｮ01ｨｨ09ｨｰ060006 ｨｬｨ ｨｰ08ｨｨｨｺ09ｨ. 03060401ｨｪ0202 ｨｬ02ｨｰ0601ｨ ｨｬｨｨ 000205ｨｹ070806ｨｪｨｨｨｺｨ 06ｨｴ02ｨｦ 010806ｨｬｨ ｨｰ060008ｨ 00ｨｨｨｨ ｨｨ 050502ｨｺｨｰ08060006080204ｨ ｨ 040506 ｨｮ09ｨｰｨ ｨｪ06090502ｨｪ06 ｨｪ0207060908020109ｨｰ0902ｨｪｨｪ0602 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｰｨ ｨｪｨｪｨｨｨｪ-ｨ 0205ｨｺ0609060006 ｨｺ06ｨｬ070502ｨｺ09ｨ 09 ｨｺ09ｨ ｨｪｨｰｨｨｨｪ06ｨｺ09ｨｨ01ｨ 0406ｨｦ [28]. 01ｨｨ0108060006ｨ ｨｪ0602 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 09 01ｨ ｨｪｨｪ06ｨｬ 0905ｨｮ ﾂｨ 02 ｨｨ0008ｨ 0506 0005ｨ 09ｨｪｨｮ06 080605ｨｹ 09 ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ06ｨｴ02ｨｬ 0102ｨｦ09ｨｰ09ｨｨｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609. 08ｨｪｨ 050600ｨｨ ﾂｨｪ04ｨｦ ｨｬ0201ｨ ｨｪｨｨ04ｨｬ ｨｨｨｬ0205 ｨｬ0209ｨｰ06 ｨｨ 09 0905ｨｮ ﾂｨ 02 ｨｨｨｪ00ｨｨｨ ｨｨ080609ｨ ｨｪｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬｨｨ ｨｺｨ ｨｰｨ 05ｨ 0404, ｨｪ06 0708ｨｨ 05ｨｰ06ｨｬ ｨｪ02 04ｨ ｨｰ08ｨ 00ｨｨ09ｨ 05ｨ 09ｨｹ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 09ｨｮ07020806ｨｺ09ｨｨ0101ｨｨ09ｨｬｨｮｨｰｨ 0404 [28]. 02ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｺ06ｨｬ070502ｨｺ090609 09 ｨｬ02ｨｰｨ 0505ｨ ｨｬｨｨ. 08ｨ ｨｺ ｨｨ 0108ｨｮ00ｨｨ02 070605ｨｨ0002ｨｪ0605ｨｹｨｪ0402 09060201ｨｨｨｪ02ｨｪｨｨ07, 06ｨ 05ｨ 01ｨ 06ｨｴｨｨ02 06-0002ｨｪ0605ｨｹｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ, 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0709050706ｨｰ0907 06ｨｰ05ｨｨ ﾂｨｪ04ｨｬｨｨ 010205ｨ ｨｰ0608ｨ ｨｬｨｨ ｨｰ08020109ｨ 0502ｨｪｨｰｨｪ060006 0302050204ｨ. 0308ｨｨ ｨｪ02ｨｦｨｰ08ｨ 05ｨｹｨｪ0401 04ｨｪｨ ﾂ02ｨｪｨｨ0701 0801 ｨｨ 09 0708ｨｨ09ｨｮｨｰ09ｨｰ09ｨｨｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ 002 090902 030205020406 ｨｪｨ 010601ｨｨｨｰ0907 09 09ｨｨ0102 ｨｺ06ｨｬ070502ｨｺ09ｨ 09 ｨｺｨ ｨｰ02010605ｨ ｨｰｨｪ04ｨｬｨｨ 0008ｨｮ0707ｨ ｨｬｨｨ 0109ｨｮ01 05ｨｨ00ｨ ｨｪ010609 [39]. 030806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 ｨｰｨ ｨｺ0302 0907060906ｨ ｨｪ04 06ｨ 08ｨ 0406090409ｨ ｨｰｨｹ ｨｺ06ｨｬ070502ｨｺ0904 09 ｨｰ08020109ｨ 0502ｨｪｨｰｨｪ04ｨｬ 83
1304ｨｨ09. 2. 05ｨｰ08ｨｮｨｺｨｰｨｮ0804 ｨｪ02ｨｺ06ｨｰ06080401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨC 01ｨｨｨｬ02080609 ｨｨ ｨｰ08ｨｨｨｬ02080609 08, 00 ｨｨ 05 ｨｰｨｨ070609 [37]. 1 ｨC 001: R 1 =OH; R 2 =H; R 3 =H; R 4 =OH; 002: R 1 =OH; R 2 =H; R 3 =OH; R 4 =H; 003: R 1 =OH; R 3 =H; R 4 =OH; 004: R 1 =OH; R 3 =OH; R 4 =H; 2 ｨC B5: R 1 =OH; R 2 =H; R 3 =H; R 4 =OH; B6: R 1 =OH; R 3 =OH; R 4 =H; B7: R 1 =OH; R 3 =H; R 4 =OH; B8: R 1 =OH; R 3 =H; R 4 =OH; 3 ｨC C1: R 1 =OH; R 2 =H; C2: R 1 =OH; 4 ｨC A2 ｨ 0506ｨｬｨｨｨｪｨｨ02ｨｬ ｨｨ 0109ｨｮ0109ｨ 0502ｨｪｨｰｨｪ06ｨｦ ｨｬ0201ｨｹ06 [34]. 0806ｨｬ070502ｨｺ0904 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｬ02ｨｰｨ 0505ｨ ｨｬｨｨ 050200ｨｺ06 090407ｨ 01ｨ 06ｨｰ 09 0609ｨ 0106ｨｺ 0708ｨｨ ｨｪ02ｨｦｨｰ08ｨ 05ｨｹｨｪ0401 0801 09 ｨｰ06ｨｬ 0905ｨｮ ﾂｨ 02, 020905ｨｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ07 05ｨｨ00ｨ ｨｪ01ｨ (070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ) ｨｪ02 0905ｨｨ03ｨｺ06ｨｬ 070802090403ｨ 02ｨｰ ｨｰｨ ｨｺ0609ｨｮ06 010507 ｨｨ06ｨｪｨ ｨｬ02ｨｰｨ 0505ｨ. 01ｨ ｨｨｨ 06050202 09ｨ 03ｨｪ04ｨｬ ｨｬ02ｨｰｨ 050506ｨｬ 07020802ｨｬ02ｨｪｨｪ06ｨｦ 09ｨ 0502ｨｪｨｰｨｪ0609ｨｰｨｨ 010507 03ｨｨ04ｨｪ02010207ｨｰ0205ｨｹｨｪ0609ｨｰｨｨ 0709050702ｨｰ0907 030205020406, ｨｺ06ｨｰ06080602 ｨｪ02 ｨｰ0605ｨｹｨｺ06 ｨｮ ﾂｨ 09ｨｰ09ｨｮ02ｨｰ 09 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06-09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ0401 07080602020909ｨ 01, ｨｪ06 ｨｨｨｬ0202ｨｰ 02020504ｨｦ 080701 0108ｨｮ00ｨｨ01 00ｨｮｨｪｨｺ02ｨｨｨｦ, ｨｰｨ ｨｺｨｨ01 ｨｺｨ ｨｺ 0108ｨ ｨｪ02ｨｪｨｨ02 ｨｨ ｨｰ08ｨ ｨｪ09070608ｨｰｨｨ080609ｨｺｨ ｨｺｨｨ090506080601ｨ, 07020802ｨｪ0609 050502ｨｺｨｰ0806ｨｪ0609, 0802ｨ ｨｺ02ｨｨｨｨ 00ｨｨ010806ｨｺ09ｨｨ05ｨｨ080609ｨ ｨｪｨｨ07, ｨｮｨｰｨｨ05ｨｨ04ｨ 02ｨｨ07 07020802ｨｺｨｨ09ｨｨ 09060106080601ｨ, 01ｨｨ09ｨｬｨｮｨｰｨ 02ｨｨ07 09ｨｮ07020806ｨｺ09ｨｨ01-ｨ ｨｪｨｨ06ｨｪｨ. 030605ｨｰ06ｨｬｨｮ 0907060906ｨ ｨｪ0609ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 090907040409ｨ ｨｰｨｹ ｨｨ06ｨｪ04 0302050204ｨ 06ｨ ｨｮ0905060905ｨｨ09ｨ 02ｨｰ 060008ｨ ｨｪｨｨ ﾂ02ｨｪｨｨ02 ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｨ ｨｪ020002ｨｬ0609060006 0302050204ｨ ｨｨ04 030205ｨｮ0106 ﾂｨｪ06-ｨｺｨｨ0302 ﾂｨｪ060006 ｨｰ08ｨ ｨｺｨｰｨ. 01020002ｨｬ06090602 030205020406 0709050702ｨｰ0907 07080608ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ0202ｨｦ, 070605ｨｰ06ｨｬｨｮ 09ｨｪｨｨ0302ｨｪｨｨ02 020006 ｨｮ080609ｨｪ07 060905ｨ ｨ 050702ｨｰ ｨｪｨ 0008ｨｮ04ｨｺｨｮ ｨｪｨ ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪｨｮ06 04ｨ ｨｴｨｨｨｰｨｪｨｮ06 09ｨｨ09ｨｰ02ｨｬｨｮ. 050907040409ｨ ｨｪｨｨ02 ｨｨ06ｨｪ0609 ｨ 0506ｨｬｨｨｨｪｨｨ07 ｨC ｨｰｨ ｨｺ0302 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ0602 07080607090502ｨｪｨｨ02 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609. 0604ｨ 04ｨｰ06ｨｺ ｨ 0506ｨｬｨｨｨｪｨｨ07 0706090403ｨ 02ｨｰ 08ｨｨ09ｨｺ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 ｨ 06050204ｨｪｨｹ06 0805ｨｹ020002ｨｦｨｬ0208ｨ, ｨ ｨｮｨｬ020802ｨｪｨｪ0602 ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ02 ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ 0907060906ｨ ｨｪ06 09ｨｪｨｨ04ｨｨｨｰｨｹ 08ｨｨ09ｨｺ 08ｨ 0409ｨｨｨｰｨｨ07 09ｨｰｨ 08 ﾂ0209ｨｺ060006 0905ｨ ｨ 06ｨｮｨｬｨｨ07 [29]. 84
1300 02020506ｨｬ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｺ06ｨｬ070502ｨｺ090609 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｬ02ｨｰｨ 0505ｨ ｨｬｨｨ, ｨｺｨ ｨｺ ｨｨ 070806ｨｰ02ｨｨｨｪ-070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ06090401 ｨｺ06ｨｬ070502ｨｺ090609, 060008ｨ ｨｪｨｨ ﾂ02ｨｪ06 030205ｨｮ0106 ﾂｨｪ06-ｨｺｨｨ0302 ﾂｨｪ04ｨｬ ｨｰ08ｨ ｨｺｨｰ06ｨｬ. 08ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ0402 ｨｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ0402 090906ｨｦ09ｨｰ09ｨ. 04ｨ ｨ 06ｨｰ, 0706090907ｨｴ02ｨｪｨｪ0401 ｨｨ04ｨｮ ﾂ02ｨｪｨｨ06 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ06ｨｦ ｨｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06 ｨｬ02ｨｪｨｹ0302, ﾂ02ｨｬ 010507 ｨｬ06ｨｪ06ｨｬ0208ｨｪ0401 0005ｨ 0906ｨｪ06ｨｨ010609 ｨｨ ｨｺｨ ｨｰ0201ｨｨｨｪ0609. 09040506 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0907060906ｨ ｨｪ04 05000002ｨｺｨｰｨｨ09ｨｪ06 ｨｨｨｪｨ ｨｺｨｰｨｨ09ｨｨ080609ｨ ｨｰｨｹ 00ｨｨ010806ｨｺ09ｨｨ05-08ｨ 01ｨｨｨｺｨ 05 ｨｨ 09ｨｮ07020806ｨｺ09ｨｨ01-ｨ ｨｪｨｨ06ｨｪ [8], 07080209060901060107 09 05ｨｰ06ｨｬ 09 ｨｪ0209ｨｺ0605ｨｹｨｺ06 08ｨ 04 ｨｪｨｨ04ｨｺ06ｨｬ060502ｨｺｨｮ050708ｨｪ0402 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰ04: 09ｨｨｨｰｨ ｨｬｨｨｨｪ04 05 ｨｨ 03. 0308ｨｨ 05ｨｰ06ｨｬ 0605ｨｨ0006ｨｬ0208ｨｪ0402 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0709050706ｨｰ0907 0008ｨ ｨｺ02ｨｨ02ｨｦ, 09 ｨｺ06ｨｰ060806ｨｦ 09090704ｨ ｨｪ06 0106 80% 06ｨ ｨｴ02ｨｦ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ [4]. 030806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0907060906ｨ ｨｪ04 ｨｮ05ｨ 0905ｨｨ09ｨ ｨｰｨｹ ｨ ｨｺｨｰｨｨ09ｨｪ0402 000608ｨｬ04 ｨｺｨｨ090506080601ｨ ｨｨ ｨ 0406ｨｰｨ ｨ 05ｨ 000601ｨ 0807 090906ｨｨｨｬ 050502ｨｺｨｰ0806ｨｪ06- ｨｨ 070806ｨｰ06ｨｪ06000608ｨｪ04ｨｬ 090906ｨｦ09ｨｰ09ｨ ｨｬ, 06ｨ 08ｨ 04ｨｮ07 0708ｨｨ 05ｨｰ06ｨｬ 0002ｨｪ06ｨｺ09ｨｨ05-08ｨ 01ｨｨｨｺｨ 05, ｨ 06050202 09ｨｰｨ ｨ ｨｨ05ｨｹｨｪ04ｨｦ, ﾂ02ｨｬ ｨ ｨｪｨ 050600ｨｨ ﾂｨｪ0402 08ｨ 01ｨｨｨｺｨ 0504 ｨｨ04 ｨｬ06ｨｪ06ｨｬ0208ｨｪ0401 0005ｨ 0906ｨｪ06ｨｨ010609 [11]. 0004ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 05ｨｰ060006 0002ｨｪ06ｨｺ09ｨｨ05-08ｨ 01ｨｨｨｺｨ 05ｨ 09 0108ｨｮ00ｨｨｨｬｨｨ 090906ｨ 0601ｨｪ04ｨｬｨｨ 08ｨ 01ｨｨｨｺｨ 05ｨ ｨｬｨｨ 0708ｨｨ090601ｨｨｨｰ ｨｺ 06ｨ 080409ｨｮ 020207ｨｨ 090906ｨ 0601ｨｪ0608ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ060006 07080602020909ｨ. 00 09ｨｨ05ｨｮ 070605ｨｨｨｬ0208ｨｪ060006 01ｨ 08ｨ ｨｺｨｰ0208ｨ 01ｨｨｨｬｨｨ ﾂ0209ｨｺ060006 09ｨｰ080602ｨｪｨｨ07, ｨ 090502010609ｨ ｨｰ0205ｨｹｨｪ06, 03ｨｨ0806ｨｺ060006 08ｨ 04ｨｪ0606ｨ 08ｨ 04ｨｨ07 00ｨｨ04ｨｨｨｺ06-01ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ01 090906ｨｦ09ｨｰ09 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, ｨｨ01 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪｨ 07 ｨｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪｨ 07 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ ｨｰｨ ｨｺｨｨ01 00ｨ ｨｺｨｰ06080609, ｨｺｨ ｨｺ 09ｨｰ020702ｨｪｨｹ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ, 00ｨ 050506ｨｨ04ｨ 02ｨｨｨｨ (ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 0609ｨｰｨ ｨｰｨｺ0609 00ｨ 0505060906ｨｦ ｨｺｨｨ090506ｨｰ04 09 ｨｬ060502ｨｺｨｮ0502), 0908060109ｨｰ0906 ｨｺ ｨ 0205ｨｺｨ ｨｬ ｨｨ ｨｺ06050000ｨｨ02ｨｨ02ｨｪｨｰ 08ｨ 0907080201020502ｨｪｨｨ07 ｨｬ020301ｨｮ 05ｨｨ07ｨｨ01ｨｪ06ｨｦ ｨｨ 090601ｨｪ06ｨｦ 00ｨ 04ｨ ｨｬｨｨ. 0308ｨｨ080601ｨ ｨｬ06ｨｪ06ｨｬ0208ｨｪ0401 040902ｨｪｨｹ0209 ｨｨ 070605060302ｨｪｨｨ02 ｨｬ0203ｨｬ06ｨｪ06ｨｬ0208ｨｪ0401 0909070402ｨｦ 06ｨｺｨ 040409ｨ 06ｨｰ 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ0602 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ. 06ｨ ｨｺ, 00ｨ 050506ｨｨ04ｨ 02ｨｨ07 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 02ｨｰ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 090601ｨｪ06ｨｦ 00ｨ 0402, ｨｪ06 09ｨｪｨｨ03ｨ 02ｨｰ 09 05ｨｨ07ｨｨ01ｨｪ06ｨｦ [33]. 02ｨ ｨｪｨｪ0402 0706 0905ｨｨ07ｨｪｨｨ06 09ｨｰ020702ｨｪｨｨ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ ｨｪｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 010609ｨｰｨ ｨｰ06 ﾂｨｪ06 070806ｨｰｨｨ09060802 ﾂｨｨ0904. 09040506 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪｨ 07 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 09 090601ｨｪ06ｨｦ 00ｨ 0402 09060408ｨ 09ｨｰｨ 02ｨｰ 06ｨｰ ｨｬ06ｨｪ06ｨｬ02080609 ｨｺ 01ｨｨｨｬ0208ｨ ｨｬ ｨｨ ｨｰ08ｨｨｨｬ0208ｨ ｨｬ, 04ｨ ｨｰ02ｨｬ 09ｨｪｨｨ03ｨ 02ｨｰ0907 ｨｺ ｨｰ02ｨｰ08ｨ ｨｬ0208ｨ ｨｬ, 09 ｨｰ06 090802ｨｬ07 ｨｺｨ ｨｺ 09 05ｨｨ07ｨｨ01ｨｪ06ｨｦ 00ｨ 0402 09 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02ｨｬ 09ｨｰ020702ｨｪｨｨ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 07ｨ 01ｨ 02ｨｰ [33]. 040204ｨｮ05ｨｹｨｰｨ ｨｰ04 0108ｨｮ00ｨｨ01 ｨ 09ｨｰ06080609 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ06ｨｰ 06ｨ ｨｮ090205ｨｨ ﾂ02ｨｪｨｨｨｨ ｨ ｨｪｨｰｨｨ08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02ｨｬ 0605ｨｨ0006ｨｬ0208ｨｪ06ｨｦ 020207ｨｨ 0708ｨｨ 070806ｨｰ02ｨｺｨ ｨｪｨｨｨｨ 08ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ0401 070806020209090609 09 05ｨｨ07ｨｨ01ｨｪ0401 0106ｨｬ02ｨｪｨ 01 [25]. 02ｨ 08ｨ 040609ｨ ｨｪｨｨ02 ｨｺ06ｨｬ070502ｨｺ090609 09 ｨ 0205ｨｺｨ ｨｬｨｨ ｨｰｨ ｨｺ0302 0905ｨｨ0702ｨｰ ｨｪｨ ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609: ｨｮ ｨ 020506ｨｺ-070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609060006 ｨｺ06ｨｬ070502ｨｺ09ｨ 06ｨｪｨ 09 0109ｨ 08ｨ 04ｨ ｨｪｨｨ0302, ﾂ02ｨｬ ｨｮ 090906ｨ 0601ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, 0708ｨｨ 05ｨｰ06ｨｬ 0202 ｨｮ08060902ｨｪｨｹ ｨｮ 06ｨ 08ｨ 040609ｨ 09030200060907 ｨｺ06ｨｬ070502ｨｺ09ｨ 04ｨ 09ｨｨ09ｨｨｨｰ ｨｺｨ ｨｺ 06ｨｰ ｨｬ060502ｨｺｨｮ050708ｨｪ060006 09ｨｰ080602ｨｪｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ, ｨｰｨ ｨｺ ｨｨ 06ｨｰ ｨｰｨｨ07ｨ ｨ 0205ｨｺｨ [6]. 0306ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 05ｨｰｨ ｨｪ0605 0708020707ｨｰ09ｨｰ09ｨｮ02ｨｰ 090907040409ｨ ｨｪｨｨ06 ｨ 0205ｨｺ0609 ｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, ｨｮ090205ｨｨ ﾂｨｨ09ｨ 07 ｨｰｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｹ ｨｨ ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 070609050201ｨｪｨｨ01 [42]. 00 0708060202090902 ｨｪ0608ｨｬｨ 05ｨｹｨｪ060006 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬｨ ｨ 09ｨｺ0608ｨ ｨｨｨｪ060906ｨｦ ｨｺｨｨ090506ｨｰ04 09 060800ｨ ｨｪｨｨ04ｨｬ02 06ｨ 08ｨ 04ｨｮ02ｨｰ0907 ｨ 09ｨｺ0608ｨ ｨ ｨｰ-08ｨ 01ｨｨｨｺｨ 05, ｨｺ06ｨｰ060804ｨｦ 0709050702ｨｰ0907 ｨｨｨｪｨｨ02ｨｨｨ ｨｰ060806ｨｬ 090906ｨ 0601ｨｪ0608ｨ 01ｨｨｨｺｨ 05ｨｹｨｪ0401 070806020209090609. 0201ｨｪｨｨｨｬ ｨｨ04 ｨ 090702ｨｺｨｰ0609 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ060006 0102ｨｦ09ｨｰ09ｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 0709050702ｨｰ0907 ｨｨ01 0907060906ｨ ｨｪ0609ｨｰｨｹ 09060909ｨｰｨ ｨｪｨ 0905ｨｨ09ｨ ｨｰｨｹ ｨ 09ｨｺ0608ｨ ｨ ｨｰ-08ｨ 01ｨｨｨｺｨ 05 [16], 0708020707ｨｰ09ｨｰ09ｨｮ07 ｨｨ09ｨｰ06ｨｴ02ｨｪｨｨ06 07ｨｮ05ｨ ｨ 09ｨｺ0608ｨ ｨｨｨｪ060906ｨｦ ｨｺｨｨ090506ｨｰ04 09 060800ｨ ｨｪｨｨ04ｨｬ02. 0306ｨｬｨｨｨｬ06 05ｨｰ060006, 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 04ｨ ｨｴｨｨｨｴｨ 06ｨｰ 06ｨｰ 06ｨｺ09ｨｨ01ｨ ｨｰｨｨ09ｨｪ06ｨｦ ｨｨｨｪｨ ｨｺｨｰｨｨ09ｨ 02ｨｨｨｨ 05ｨｪ01060002ｨｪｨｪ0402 ｨｪｨｨ04ｨｺ06ｨｬ060502ｨｺｨｮ050708ｨｪ0402 060800ｨ ｨｪｨｨ ﾂ0209ｨｺｨｨ02 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰ04 ｨC ｨ 05ｨｹ00ｨ -ｨｰ06ｨｺ060002080605 [27] ｨｨ 000506ｨｰｨ ｨｰｨｨ06ｨｪ [36], ﾂｨｰ06 0706040906050702ｨｰ ｨｮ090205ｨｨ ﾂｨｨｨｰｨｹ 08020402080904 09ｨｨ09ｨｰ02ｨｬ04 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ06ｨｦ 04ｨ ｨｴｨｨｨｰ04 060800ｨ ｨｪｨｨ04ｨｬｨ. 09ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609. 00ｨ 03ｨｪ02ｨｦ03ｨｨｨｬ ｨ 090702ｨｺｨｰ06ｨｬ 07080607090502ｨｪｨｨ07 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 0506ｨ 060006 07080207ｨ 08ｨ ｨｰｨ 0709050702ｨｰ0907 020006 ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｹ. 08ｨ 090608ｨ 02ｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 030205ｨｮ0106 ﾂｨｪ06-ｨｺｨｨ0302 ﾂｨｪ06ｨｬ ｨｰ08ｨ ｨｺｨｰ02 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ ｨｨ01 ｨｬ060502ｨｺｨｮ050708ｨｪ060006 090209ｨ. In vitro 09 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02ｨｬ ｨｬ06ｨｪ0609050607 ｨｺ0502ｨｰ06ｨｺ ｨｰ06ｨｪｨｺ060006 ｨｺｨｨ0302 ﾂｨｪｨｨｨｺｨ ﾂ0205060902ｨｺｨ ｨｬ06ｨｪ06ｨｬ020804, 01ｨｨｨｬ020804 ｨｨ ｨｰ08ｨｨｨｬ020804 ｨ ｨ 090608ｨ ｨｨ080609ｨ 05ｨｨ09ｨｹ 09 0601ｨｨｨｪｨ ｨｺ060906ｨｦ 09ｨｺ06080609ｨｰｨｹ06 [38]. 0308ｨｨ 05ｨｰ06ｨｬ 0706ｨｰ06ｨｺ ｨ ｨ 090608ｨ 02ｨｨｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 080200ｨｨ09ｨｰ08ｨｨ080609ｨ 050907 ｨｪｨ ｨｮ080609ｨｪ02 ｨｬｨ ｨｪｨｪｨｨｨｰ0605ｨ ｨC 00ｨｨ01080600ｨｨ05ｨｹｨｪ060006 ｨｬｨ 08ｨｺ0208ｨ 09080201ｨｪ02ｨｦ 070806010601ｨｨｨｬ0609ｨｰｨｨ. 030605ｨｰ06ｨｬｨｮ 09070605ｨｪ02 0902080607ｨｰｨｪ06, ﾂｨｰ06 ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｹ 01ｨｨｨｬ02080609 ｨｨ ｨｰ08ｨｨｨｬ02080609 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ﾂ02080204 030205ｨｮ0106 ﾂｨｪ06-ｨｺｨｨ0302 ﾂｨｪ04ｨｦ ｨｰ08ｨ ｨｺｨｰ 0906070609ｨｰｨ 09ｨｨｨｬｨ 09 ｨ ｨ 090608ｨ 02ｨｨ02ｨｦ ｨｺｨ ｨｰ0201ｨｨｨｪ0609. 0205ｨｨ0006ｨｬ020804 0906 09080201ｨｪ02ｨｦ 09ｨｰ020702ｨｪｨｹ06 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ 7 0708ｨ ｨｺｨｰｨｨ ﾂ0209ｨｺｨｨ ｨｪ02 ｨ ｨ 090608ｨ ｨｨ080609ｨ 05ｨｨ09ｨｹ ｨｺ0502ｨｰ06 ﾂｨｪ04ｨｬ ｨｬ06ｨｪ0609050602ｨｬ. 090605ｨｹ03ｨ 07 85
13 ﾂｨ 09ｨｰｨｹ 0008ｨ ｨｺ02ｨｨｨｦ 070605ｨｨｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｨ ﾂｨ 09ｨｰｨｨ ﾂｨｪ06 ｨｰ08ｨｨｨｬ0208ｨ 052 ｨ 0405ｨ 09090704ｨ ｨｪｨ 09 ｨｺ0502ｨｰｨｺｨ ｨｬｨｨ 04ｨ 09 ﾂ02ｨｰ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ07 ｨｺ06ｨｬ070502ｨｺ090609 09 ｨｬ02ｨｬｨ 08ｨ ｨｪｨｪ04ｨｬｨｨ ｨ 0205ｨｺｨ ｨｬｨｨ [38]. 00 ｨｮ09050609ｨｨ0701 in vivo, 0601ｨｪｨ ｨｺ06, ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｹ 070605ｨｨｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｬ060302ｨｰ 09060408ｨ 09ｨｰｨ ｨｰｨｹ 0706 080701ｨｮ 0708ｨｨ ﾂｨｨｨｪ. 09040506 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 09 0908020102 ｨｨ09ｨｺｨｮ0909ｨｰ0902ｨｪｨｪ060006 030205ｨｮ0106 ﾂｨｪ060006 0906ｨｺｨ ｨｪｨ ｨ 050601ｨ 02ｨｰ0907 ｨ 0409ｨｰ08ｨ 07 0102ｨｺ06ｨｬ070604ｨｨ02ｨｨ07 070605ｨｨｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609-0002ｨｺ09ｨ ｨｬ02080609 ｨｪｨ ｨｬ06ｨｪ06ｨｬ020804 ｨｨ 01ｨｨｨｬ020804 [43], ｨｺ06ｨｰ06080402 050200ｨｺ06 ｨ ｨ 090608ｨ ｨｨ08ｨｮ06ｨｰ0907 09ｨｰ02ｨｪｨｺｨ ｨｬｨｨ ｨｺｨｨ0302 ﾂｨｪｨｨｨｺｨ. 05ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ04ｨｦ 09ｨｺ05ｨ 01 09 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 ｨ ｨｨ06010609ｨｰｨｮ07ｨｪ0609ｨｰｨｨ 070605ｨｨｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｬ060302ｨｰ 09ｨｪ0609ｨｨｨｰｨｹ ｨｨ ｨｺｨｨ0302 ﾂｨｪｨ 07 00050608ｨ, ｨｺ06ｨｰ0608ｨ 07 0907060906ｨ ｨｪｨ ｨｺｨ ｨｰｨ ｨ 0605ｨｨ04ｨｨ080609ｨ ｨｰｨｹ 070605ｨｨｨｬ0208ｨｪ0402 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 09 ｨｪｨｨ04ｨｺ06ｨｬ060502ｨｺｨｮ050708ｨｪ0402 0002ｨｪ0605ｨｹｨｪ0402 ｨｺｨｨ090506ｨｰ04 [17]. 0308ｨｨ 0906040102ｨｦ09ｨｰ09ｨｨｨｨ in vitro ﾂ0205060902 ﾂ0209ｨｺ06ｨｦ 0002ｨｺｨ 05ｨｹｨｪ06ｨｦ 0005060804 ｨｪｨ 09ｨｬ0209ｨｹ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 0906 09ｨｰ020702ｨｪｨｹ06 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ 6 ｨｨ 090906ｨ 0601ｨｪ06ｨｦ 06ｨｰ 01ｨｨｨｬ02080609 ｨ 0405ｨ 06ｨ ｨｪｨ 08ｨｮ0302ｨｪｨ ｨｨｨｪｨｰ02ｨｪ09ｨｨ09ｨｪｨ 07 (ｨｪｨ 90%) 01020008ｨ 01ｨ 02ｨｨ07 09ｨｬ0209ｨｨ. 00 ｨｺｨ ﾂ0209ｨｰ0902 0609ｨｪ0609ｨｪ060006 ｨｬ02ｨｰｨ ｨ 0605ｨｨｨｰｨ 090401020502ｨｪｨ 3-(m-00ｨｨ010806ｨｺ09ｨｨ0002ｨｪｨｨ05)-07080607ｨｨ06ｨｪ0609ｨ 07 ｨｺｨｨ090506ｨｰｨ, ｨ 09 ｨｬ02ｨｪｨｹ03ｨｨ01 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ 01 0202 p-00ｨｨ010806ｨｺ09ｨｨ0002ｨｪｨｨ05060904ｨｦ ｨｨ0406ｨｬ0208 ｨｨ 080701 0108ｨｮ00ｨｨ01 0002ｨｪ0605ｨｹｨｪ0401 ｨｺｨｨ090506ｨｰ [40], ｨｺ06ｨｰ06080402 0907060906ｨ ｨｪ04 070806ｨｪｨｨｨｺｨ ｨｰｨｹ ﾂ02080204 0905ｨｨ04ｨｨ09ｨｰｨｮ06 ｨｺｨｨ0302 ﾂｨｪｨｨｨｺｨ. 05ｨｨ09ｨｰ02ｨｬｨｪ0402 05000002ｨｺｨｰ04 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 06ｨｬｨｬｨｮｨｪ06ｨｬ0601ｨｮ05ｨｨ08ｨｮ06ｨｴ0202 0102ｨｦ09ｨｰ09ｨｨ02. 090605ｨｹ03ｨｨｨｪ09ｨｰ0906 ｨｨ04 0609ｨｪ0609ｨｪ0401 070806020209090609 ｨｺ0502ｨｰ06 ﾂｨｪ06ｨｦ 080200ｨｮ050702ｨｨｨｨ ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｹｨｪ04 ｨｺ ｨ ｨ 05ｨ ｨｪ09ｨｮ ｨｬ020301ｨｮ 06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨ ｨｬｨｨ ｨｨ ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨ ｨｬｨｨ. 020708020502050706ｨｴｨｨ02 09ｨｰｨ 01ｨｨｨｨ 09 09ｨｨ00ｨｪｨ 05ｨｹｨｪ06ｨｦ ｨｰ08ｨ ｨｪ0901ｨｮｨｺ02ｨｨｨｨ, ｨｰｨ ｨｺｨｨ02 ｨｺｨ ｨｺ 000609000608ｨｨ05ｨｨ080609ｨ ｨｪｨｨ02 ｨ 0205ｨｺ0609 ｨｨ 090907040409ｨ ｨｪｨｨ02 00ｨ ｨｺｨｰ06080609 ｨｰ08ｨ ｨｪ09ｨｺ08ｨｨ0702ｨｨｨｨ ｨｪｨ 020108, ｨｬ0601ｨｮ05ｨｨ08ｨｮ06ｨｰ0907 09ｨｪｨｮｨｰ08ｨｨｨｺ0502ｨｰ06 ﾂｨｪ04ｨｬ 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06-09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ04ｨｬ 0706ｨｰ02ｨｪ02ｨｨｨ 0506ｨｬ. 06ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ04 09 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬｨｨ 0706ｨｺｨ 04ｨ 05ｨｨ ｨｨ01 0907060906ｨ ｨｪ0609ｨｰｨｹ 01ｨｨ0000020802ｨｪ02ｨｨ080609ｨ ｨｪｨｪ06 0905ｨｨ07ｨｰｨｹ ｨｪｨ 05ｨｺ090708020909ｨｨ06 0002ｨｪ0609 09 ｨｺｨｮ05ｨｹｨｰｨｮ0802 ｨｺ0502ｨｰ06ｨｺ, ｨｬ0601ｨｮ05ｨｨ080609ｨ ｨｰｨｹ ｨｨｨｬｨｬｨｮｨｪｨｪ04ｨｦ 06ｨｰ0902ｨｰ 09 ｨｬｨ ｨｺ080600ｨ 00ｨ 01, 09ｨｰｨｨｨｬｨｮ05ｨｨ08ｨｮ07 090401020502ｨｪｨｨ02 ｨ 05ｨｹ00ｨ -00ｨ ｨｺｨｰ0608ｨ ｨｪ02ｨｺ080604ｨ 0607ｨｮ01060502ｨｦ [32]. 09040506 06ｨｰｨｬ02 ﾂ02ｨｪ06 ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ06ｨｴ0202 0905ｨｨ07ｨｪｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, 090401020502ｨｪｨｪ0401 ｨｨ04 ｨｺ060804 ｨｬ060809ｨｺ06ｨｦ 090609ｨｪ04 Pinus maritima, ｨｪｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 06ｨｺ09ｨｨ01ｨ ｨ 0406ｨｰｨ (NO) 09 ｨｬｨ ｨｺ080600ｨ 00ｨ 01 [45], ﾂｨｰ06 ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ 06ｨ ｨｮ090506090502ｨｪ06 ｨｺｨ ｨｺ ｨｪ0207060908020109ｨｰ0902ｨｪｨｪ04ｨｬ 0905ｨｨ07ｨｪｨｨ02ｨｬ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ 070806ｨｰ02ｨｺｨ ｨｪｨｨ02 09ｨｪｨｮｨｰ08ｨｨｨｺ0502ｨｰ06 ﾂｨｪ0401 070806020209090609, ｨｰｨ ｨｺ ｨｨ 060706090802010609ｨ ｨｪｨｪ04ｨｬ ｨC ﾂ02080204 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 09 05ｨｨ0706070605ｨｨ09ｨ 01ｨ 08ｨｨ01ｨ ｨｬｨｨ [7]. 05ｨｰ020702ｨｪｨｹ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｰｨ ｨｺ0302 ｨｨ0008ｨ 05ｨ 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪｨｮ06 080605ｨｹ 09 ｨｪｨ 0708ｨ 090502ｨｪｨｪ0609ｨｰｨｨ 05000002ｨｺｨｰｨ. 030905ｨｨ 01ｨｨｨｬ020804 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 001 ｨｨ 002 0708060709050705ｨｨ 09080201ｨｪ0606 ｨｨｨｪ00ｨｨｨ ｨｨ08ｨｮ06ｨｴｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 0708ｨｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨｨｨ NO, ｨｰ06 ｨｰ08ｨｨｨｬ0208 052 ｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ04ｨｦ 05ｨｺ09ｨｰ08ｨ ｨｺｨｰ 0003ｨｨｨｺｨｪ060002ｨｪ060503, ｨｨｨｬ0206ｨｴｨｨｨｦ 09 09080201ｨｪ02ｨｬ ｨ 06050202 09040906ｨｺｨｮ06, ﾂ02ｨｬ 2, 09ｨｰ020702ｨｪｨｹ 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ, 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ06 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 05ｨｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ02 NO, ｨｨｨｪｨｨ02ｨｨｨｨ08ｨｮ02ｨｬ0602 ｦﾃ-ｨｨｨｪｨｰ020800020806ｨｪ06ｨｬ [32]. 00 08070102 08ｨ ｨ 06ｨｰ 0706ｨｺｨ 04ｨ ｨｪ06 0905ｨｨ07ｨｪｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ 05ｨｺ090708020909ｨｨ06 ｨｨ 0902ｨｺ080202ｨｨ06 ｨｨｨｪｨｰ02080502ｨｦｨｺｨｨｨｪｨ -1ｦﾂ 09 ｨｬ06ｨｪ0607010208ｨｪ0401 ｨｺ0502ｨｰｨｺｨ 01 070208ｨｨ000208ｨｨ ﾂ0209ｨｺ06ｨｦ ｨｺ080609ｨｨ [15]. 0205ｨｨ0006ｨｬ020804 0906 09ｨｰ020702ｨｪｨｹ06 070605ｨｨｨｬ0208ｨｨ04ｨ 02ｨｨｨｨ 0106 4 09ｨｪｨｨ03ｨ 05ｨｨ 05ｨｺ090708020909ｨｨ06 0002ｨｪｨ ｨｨｨｪｨｰ02080502ｨｦｨｺｨｨｨｪｨ -1ｦﾂ, ｨ 0906 09ｨｰ020702ｨｪｨｹ06 5ｨC10 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 05ｨｨ 0202. 030806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04, 090401020502ｨｪｨｪ0402 ｨｨ04 ｨｺｨ ｨｺｨ 06, 0708020707ｨｰ09ｨｰ090609ｨ 05ｨｨ 07080605ｨｨ000208ｨ 02ｨｨｨｨ 05ｨｨｨｬ000602ｨｨｨｰ0609 ｨｨ 06ｨ 08ｨ 040609ｨ ｨｪｨｨ06 IGG 09 06ｨｰ0902ｨｰ ｨｪｨ ｨｬｨｨｨｰ060002ｨｪ 00ｨｨｨｰ060002ｨｬｨ 00000506ｨｰｨｨｨｪｨｨｨｪ. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｬ0201ｨ ｨｪｨｨ04ｨｬ0609 ｨ ｨｪｨｰｨｨ09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ060006 0102ｨｦ09ｨｰ09ｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ ｨｨｨｪ00ｨｨｨ ｨｨ080609ｨ ｨｪｨｨ02 ｨ 01000204ｨｨｨｨ 05ｨｨｨｬ000602ｨｨｨｰ0609 ｨｺ ｨｺｨ 0806ｨｰｨｨｨｪ0602ｨｨｨｰｨ ｨｬ, ｨｨｨｪ01ｨｮ02ｨｨ080609ｨ ｨｪｨｪ0602 IGG [10]. 00 ｨｮ09050609ｨｨ0701 ｨｨｨｬｨｬｨｮｨｪｨｪ060006 010200ｨｨ02ｨｨｨｰｨ ｨｮ ｨｬ040302ｨｦ, 09040409ｨ ｨｪｨｪ060006 070608ｨ 0302ｨｪｨｨ02ｨｬ 0802ｨｰ080609ｨｨ08ｨｮ0906ｨｬ LP-BM5, 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 09ｨｪｨｨ03ｨ 05ｨｨ 0106 ｨｪ0608ｨｬ04 070609040302ｨｪｨｪ04ｨｦ ｨｮ08060902ｨｪｨｹ ｨｨｨｪｨｰ02080502ｨｦｨｺｨｨｨｪｨ -6, ｨ 0708ｨｨ 010806ｨｪｨｨ ﾂ0209ｨｺ06ｨｬ ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨｨｨ 05ｨｰｨ ｨｪ0605ｨ ｨC ｨｨｨｪｨｰ02080502ｨｦｨｺｨｨｨｪｨ -10. 080806ｨｬ02 ｨｰ060006, 06ｨｪｨｨ ｨｮ090205ｨｨ ﾂｨｨ09ｨ 05ｨｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｺ0502ｨｰ06ｨｺ-ｨｺｨｨ050502080609 [14]. 0005ｨｨ07ｨｪｨｨ02 ｨｪｨ 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰｨｮ06 09ｨｨ09ｨｰ02ｨｬｨｮ. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｪｨ ｨｨｨ 06050202 ｨｨ04ｨｮ ﾂ02ｨｪｨｪ0401 ｨ 090702ｨｺｨｰ0609 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 0709050702ｨｰ0907 ｨｨ01 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ 08ｨ 0405ｨｨ ﾂｨｪ0402 ｨｮ ﾂｨ 09ｨｰｨｺｨｨ 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰ06ｨｦ 09ｨｨ09ｨｰ02ｨｬ04. 0607ｨｨ0102ｨｬｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ02 ｨｨ09090502010609ｨ ｨｪｨｨ07, 07080609020102ｨｪｨｪ0402 09 09ｨｰ08ｨ ｨｪｨ 01, ｨｪｨ 09020502ｨｪｨｨ02 ｨｺ06ｨｰ06080401 ｨｰ08ｨ 01ｨｨ02ｨｨ06ｨｪｨｪ06 ｨｮ0706ｨｰ0802ｨ 050702ｨｰ ｨ 0605ｨｹ030602 ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ, 0706ｨｺｨ 04ｨ 05ｨｨ 09ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ06 09ｨｪｨｨ0302ｨｪｨｪ04ｨｦ ｨｮ08060902ｨｪｨｹ 09ｨｬ0208ｨｰｨｪ0609ｨｰｨｨ 06ｨｰ 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰ0401 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ, ｨｪ0209ｨｬ06ｨｰ0807 ｨｪｨ 01ｨｨ02ｨｰｨｮ 09 09040906ｨｺｨｨｨｬ 090601020803ｨ ｨｪｨｨ02ｨｬ ｨｪｨ 0904ｨｴ02ｨｪｨｪ0401 03ｨｨ080609. 02ｨ ｨｪｨｪ0602 07090502ｨｪｨｨ02 070605ｨｮ ﾂｨｨ0506 86
13ｨｪｨ 0409ｨ ｨｪｨｨ02 000008ｨ ｨｪ02ｨｮ0409ｨｺ060006 07ｨ 08ｨ 0106ｨｺ09ｨ 03. 070706ｨｰ0802ｨ 0502ｨｪｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｨ 09ｨｨｨｪ, ｨ 0600ｨ ｨｰ0401 070605ｨｨ0002ｨｪ0605ｨ ｨｬｨｨ, 09090704ｨ ｨｪ06 0906 09ｨｪｨｨ0302ｨｪｨｨ02ｨｬ 080701ｨ 00ｨ ｨｺｨｰ06080609 08ｨｨ09ｨｺｨ 08ｨ 0409ｨｨｨｰｨｨ07 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰ0401 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ, ｨｰｨ ｨｺｨｨ01 ｨｺｨ ｨｺ 070609040302ｨｪｨｪ0602 ｨｺ08060907ｨｪ0602 01ｨ 090502ｨｪｨｨ02 ｨｨ ｨｮ090205ｨｨ ﾂ02ｨｪｨｪ04ｨｦ ｨｮ08060902ｨｪｨｹ 0106050209ｨｰ0208ｨｨｨｪｨ 09 ｨｺ080609ｨｨ [35]. 0209ｨｪ0609ｨｪ0402 ｨｬ0201ｨ ｨｪｨｨ04ｨｬ04, 06ｨ ｨｮ0905060905ｨｨ09ｨ 06ｨｴｨｨ02 04ｨ ｨｴｨｨｨｰｨｪ0602 0102ｨｦ09ｨｰ09ｨｨ02 070605ｨｨ0002ｨｪ0605ｨｹｨｪ060006 ｨｺ06ｨｬ070502ｨｺ09ｨ ｨｺ08ｨ 09ｨｪ0401 09ｨｨｨｪ, 09ｨｺ0506 ﾂｨ 06ｨｰ 09 0902ｨ 07 04ｨ ｨｴｨｨｨｰｨｮ 06ｨｰ 06ｨｺ09ｨｨ01ｨ ｨｰｨｨ09ｨｪ06ｨｦ ｨｬ0601ｨｨ00ｨｨｨｺｨ 02ｨｨｨｨ 05ｨｨ0706070806ｨｰ02ｨｨｨｪ0609 ｨｪｨｨ04ｨｺ06ｨｦ 070506ｨｰｨｪ0609ｨｰｨｨ (09030103) [30], ｨｨｨｪ00ｨｨｨ ｨｨ080609ｨ ｨｪｨｨ02 ｨ 00080200ｨ 02ｨｨｨｨ ｨｰ0806ｨｬｨ 0602ｨｨｨｰ0609 [13] ｨｨ 09ｨｰｨｨｨｬｨｮ050702ｨｨ06 0902ｨｺ080202ｨｨｨｨ 05ｨｪ0106ｨｰ0205ｨｨｨ 05ｨｹｨｪ060006 06ｨｺ09ｨｨ01ｨ ｨ 0406ｨｰｨ [9]. 070706ｨｰ0802ｨ 0502ｨｪｨｨ02 ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ [18], 070605ｨｨ0002ｨｪ0605ｨｹｨｪ060006 ｨｺ06ｨｬ070502ｨｺ09ｨ ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ [12] ｨｨ05ｨｨ 0102ｨ 05ｨｺ06000605ｨｨ04ｨｨ080609ｨ ｨｪｨｪ060006 ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ [41] ｨｮ090205ｨｨ ﾂｨｨ09ｨ 0506 ｨ ｨｪｨｰｨｨ06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 0705ｨ 04ｨｬ04 ｨｺ080609ｨｨ ｨｪ0207060908020109ｨｰ0902ｨｪｨｪ06 0706090502 0708ｨｨ02ｨｬｨ, ｨ ｨ ｨ 04ｨ 05ｨｹｨｪｨｮ06 ｨ ｨｪｨｰｨｨ06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪｨｮ06 ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 0705ｨ 04ｨｬ04 ｨC 0706090502 080200ｨｮ050708ｨｪ060006 0706ｨｰ0802ｨ 0502ｨｪｨｨ07 0106 ﾂ02ｨｰ04080201 ｨｪ02010205ｨｹ. 030609040302ｨｪｨｨ07 ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 0705ｨ 04ｨｬ04 ｨｪ02 ｨｪｨ ｨ 050601ｨ 050609ｨｹ 070601 0905ｨｨ07ｨｪｨｨ02ｨｬ ｨ 0205060006 09ｨｨｨｪｨ [41] ｨｨ05ｨｨ 090601ｨｺｨｨ [48], ｨｺ06ｨｰ06080402 05ｨｨｨ 06 ｨｪ02 090601020803ｨ ｨｰ, 05ｨｨｨ 06 090601020803ｨ ｨｰ ｨｪ02ｨ 0605ｨｹ030602 ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 070605ｨｨ0002ｨｪ06050609. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｬ0201ｨ ｨｪｨｨ04ｨｬ0609 04ｨ ｨｴｨｨｨｰ04 09030103 06ｨｰ 06ｨｺ09ｨｨ01ｨ ｨｰｨｨ09ｨｪ06ｨｦ ｨｬ0601ｨｨ00ｨｨｨｺｨ 02ｨｨｨｨ ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ ｨｨｨｪｨｰ020008ｨ 02ｨｨ07 ｨｬ060502ｨｺｨｮ05 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 09030103 ｨｨ 04ｨ ｨｴｨｨｨｰｨ ｨｪ02ｨｪｨ 0904ｨｴ02ｨｪｨｪ06ｨｦ 03ｨｨ08ｨｪ06ｨｺｨｨ090506ｨｰｨｪ06ｨｦ 090609ｨｰｨ 09050706ｨｴ02ｨｦ ｨｰ08ｨｨ0005ｨｨ020208ｨｨ010609 09 ｨｨ01 090609ｨｰｨ 0902 [21]. 0208ｨｮ00ｨｨｨｬ ｨｬ0201ｨ ｨｪｨｨ04ｨｬ06ｨｬ, 07060908020109ｨｰ0906ｨｬ ｨｺ06ｨｰ0608060006 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ04 0907060906ｨ ｨｪ04 0708020707ｨｰ09ｨｰ090609ｨ ｨｰｨｹ 08ｨ 0409ｨｨｨｰｨｨ06 090208020102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰ0401 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ, 0709050702ｨｰ0907 ｨｨｨｪ00ｨｨｨ ｨｨ080609ｨ ｨｪｨｨ02 ｨ 00080200ｨ 02ｨｨｨｨ ｨｰ0806ｨｬｨ 0602ｨｨｨｰ0609. 06ｨ ｨｺ, ｨｮ ｨｺ080409 ｨｺ08ｨ 09ｨｪ0602 09ｨｨｨｪ06 ｨｨ 0102ｨ 05ｨｺ06000605ｨｨ04ｨｨ080609ｨ ｨｪｨｪ0602 ｨｺ08ｨ 09ｨｪ0602 09ｨｨｨｪ06 ｨｮ090205ｨｨ ﾂｨｨ09ｨ 0506 090802ｨｬ07 09090208ｨｰ0409ｨ ｨｪｨｨ07 ｨｺ080609ｨｨ ｨｨ ｨｮｨｬ02ｨｪｨｹ03ｨ 0506 08ｨ 04ｨｬ0208 ｨｰ0806ｨｬｨ ｨ, ｨ ｨｰｨ ｨｺ0302 ｨ 01000204ｨｨ06 ｨｰ0806ｨｬｨ 0602ｨｨｨｰ0609 ｨｺ ｨｺ060505ｨ 0002ｨｪｨｮ [46]. 0902050602 09ｨｨｨｪ06 ｨｨ 05ｨｰｨｨ05060904ｨｦ 0907ｨｨ08ｨｰ ｨｰｨ ｨｺ060006 0102ｨｦ09ｨｰ09ｨｨ07 ｨｪ02 06ｨｺｨ 040409ｨ 05ｨｨ. 0606ｨｰ 00ｨ ｨｺｨｰ, ﾂｨｰ06 ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ02 06ｨ 0204ｨｹ07ｨｪｨ ｨｬｨｨ ｨ 070205ｨｹ09ｨｨｨｪ0609060006 ｨｨ 000802ｨｦ070008ｨｮｨｺｨｰ0609060006 0906ｨｺ0609, ｨ 0600ｨ ｨｰ0401 ｨ ｨｨ060005ｨ 0906ｨｪ06ｨｨ01ｨ ｨｬｨｨ, ｨｪ02 0907060906ｨ 09ｨｰ090609ｨ 0506 09ｨｪｨｨ0302ｨｪｨｨ06 09ｨｺ06080609ｨｰｨｨ ｨｺ060505ｨ 0002ｨｪ-ｨｨｨｪ01ｨｮ02ｨｨ080609ｨ ｨｪｨｪ06ｨｦ ｨ 00080200ｨ 02ｨｨｨｨ ｨｰ0806ｨｬｨ 0602ｨｨｨｰ0609, 09 06ｨｰ05ｨｨ ﾂｨｨ02 06ｨｰ 09ｨｨｨｪ060008ｨ 01ｨｪ060006 0906ｨｺｨ [31], 070601ｨｰ0902080301ｨ 02ｨｰ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 0005ｨ 0906ｨｪ06ｨｨ010609 ｨｨｨｬ02ｨｪｨｪ06 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ060906ｨｦ 0008ｨｮ070704. 00 070605ｨｹ04ｨｮ 05ｨｰ060006 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ02ｨｰ ｨｨ 0907060906ｨ ｨｪ0609ｨｰｨｹ 09ｨｮｨｬｨｬｨ 08ｨｪ06ｨｦ 070605ｨｨ0002ｨｪ0605ｨｹｨｪ06ｨｦ 0008ｨ ｨｺ02ｨｨｨｨ 09ｨｨｨｪ060008ｨ 01ｨ ｨｨｨｪ00ｨｨｨ ｨｨ080609ｨ ｨｰｨｹ ｨｰ0806ｨｬｨ ｨｨｨｪｨｨｨｪ01ｨｮ02ｨｨ080609ｨ ｨｪｨｪｨｮ06 ｨ 00080200ｨ 02ｨｨ06 ｨｰ0806ｨｬｨ 0602ｨｨｨｰ0609 ｨｮ ｨｺ080409 [47]. 05ｨｮｨｴ0209ｨｰ0902ｨｪｨｪ04ｨｦ 09ｨｺ05ｨ 01 09 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ0602 0102ｨｦ09ｨｰ09ｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ 0902080102 ﾂｨｪ06-090609ｨｮ01ｨｨ09ｨｰｨｮ06 09ｨｨ09ｨｰ02ｨｬｨｮ 09ｨｪ0609ｨｨｨｰ ｨｨ ｨｨ01 0904ｨ ｨｨｨｬ060102ｨｦ09ｨｰ09ｨｨ02 09 090609ｨｮ01ｨｨ09ｨｰ06ｨｦ 09ｨｰ02ｨｪｨｺ06ｨｦ. 00ｨｨｨｪ060008ｨ 01ｨｪ0602 ｨｺ08ｨ 09ｨｪ0602 09ｨｨｨｪ06, 070605ｨｨ0002ｨｪ0605ｨｹｨｪｨ 07 0008ｨ ｨｺ02ｨｨ07 ｨｺ08ｨ 09ｨｪ060006 09ｨｨｨｪｨ, ｨ ｨｰｨ ｨｺ0302 05ｨｺ09ｨｰ08ｨ ｨｺｨｰ ｨｺ060804 090609ｨｪ04 0904040409ｨ 05ｨｨ 05ｨｪ0106ｨｰ0205ｨｨｨｦ-04ｨ 09ｨｨ09ｨｨｨｬｨｮ06 080205ｨ ｨｺ09ｨ 02ｨｨ06 ｨｨ040605ｨｨ080609ｨ ｨｪｨｪ06ｨｦ ｨ 0608ｨｰ04 ｨｺ08040904 in vitro [20]. 0808ｨ ｨｺ02ｨｨ07 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨ 0405ｨ ｨｨ0102ｨｪｨｰｨｨ00ｨｨ02ｨｨ080609ｨ ｨｪｨ ｨｺｨ ｨｺ ｨ ｨｺｨｰｨｨ09ｨｪ04ｨｦ ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰ 05ｨｺ09ｨｰ08ｨ ｨｺｨｰｨ, 06ｨ ｨｮ0905060905ｨｨ09ｨ 06ｨｴｨｨｨｦ ｨｪｨ ｨ 050601ｨ 02ｨｬｨｮ06 05ｨｪ0106ｨｰ0205ｨｨｨ 05ｨｹｨｪｨｮ06 080205ｨ ｨｺ09ｨ 02ｨｨ06. 030609ｨｺ0605ｨｹｨｺｨｮ 0601ｨｪｨｨｨｬ ｨｨ04 05ｨｪ01060002ｨｪｨｪ0401 ｨｬ0201ｨｨｨ ｨｰ06080609 090609ｨｮ01ｨｨ09ｨｰ06ｨｦ 080205ｨ ｨｺ09ｨ 02ｨｨｨｨ 0709050702ｨｰ0907 NO, 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ-06ｨ ｨｮ090506090502ｨｪｨｪ0602 0102ｨｦ09ｨｰ09ｨｨ02 ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ 09040409ｨ ｨｪ06 ｨｺｨ ｨｺ ｨｮ05ｨ 0905ｨｨ09ｨ ｨｪｨｨ02ｨｬ 09ｨｮ07020806ｨｺ09ｨｨ01ｨｪ0401 08ｨ 01ｨｨｨｺｨ 050609, 0904040409ｨ 06ｨｴｨｨ01 ｨｨｨｪｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ06 NO, ｨｰｨ ｨｺ ｨｨ ｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ02ｨｦ 020006 ｨ ｨｨ0609ｨｨｨｪｨｰ0204ｨ. 030208090702ｨｺｨｰｨｨ0904 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ07 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 010507 ｨｺ06080802ｨｺ02ｨｨｨｨ ｨｬ02ｨｰｨ ｨ 0605ｨｨ ﾂ0209ｨｺｨｨ01 ｨｪｨ 08ｨｮ0302ｨｪｨｨｨｦ, 0904040409ｨ 02ｨｬ0401 ｨ 05ｨｺ0600060502ｨｬ 0604090209ｨｰｨｪ06, ﾂｨｰ06 05ｨｰｨ ｨｪ0605 070605ｨｪ0609ｨｰｨｹ06 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｨ08ｨｮ02ｨｰ0907 09 060800ｨ ｨｪｨｨ04ｨｬ02, 0708ｨｨ ﾂ02ｨｬ ｨｪ02 ｨｬ02ｨｪ0202 80% 05ｨｰｨ ｨｪ0605ｨ 06ｨｺｨｨ09050702ｨｰ0907 09 0702 ﾂ02ｨｪｨｨ, 09 ｨｮ ﾂｨ 09ｨｰｨｨ02ｨｬ 0109ｨｮ01 0609ｨｪ0609ｨｪ0401 000208ｨｬ02ｨｪｨｰ0609: ｨ 05ｨｺ06000605ｨｹ010200ｨｨ0108060002ｨｪｨ 0404 (080201) (08.08. 1.1.1.1) ｨｨ ｨ 05ｨｹ010200ｨｨ01010200ｨｨ0108060002ｨｪｨ 0404 (08050201) (08.08. 1.2.1.3). 02ｨ ｨ 000208ｨｬ02ｨｪｨｰｨ 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨ ｨｺ020207ｨｰ0608ｨ 01 + ｨｨ09070605ｨｹ04ｨｮ06ｨｰ 010802 +, 070605ｨｰ06ｨｬｨｮ 06ｨｺｨｨ090502ｨｪｨｨ02 05ｨｰｨ ｨｪ0605ｨ 090607080609060301ｨ 02ｨｰ0907 ｨｪｨ ｨｺ06070502ｨｪｨｨ02ｨｬ 09060909ｨｰｨ ｨｪ06090502ｨｪｨｪ06ｨｦ 020006 000608ｨｬ04 (01080201) ｨｨ 09ｨｪｨｨ0302ｨｪｨｨ02ｨｬ 090601020803ｨ ｨｪｨｨ07 06ｨｺｨｨ090502ｨｪｨｪ06ｨｦ. 06ｨｰ06 06ｨ 09ｨｰ0607ｨｰ0205ｨｹ09ｨｰ0906 ｨｨｨｬ0202ｨｰ 0708ｨｨｨｪ02ｨｨ07ｨｨｨ 05ｨｹｨｪ0602 04ｨｪｨ ﾂ02ｨｪｨｨ02 010507 ｨｰ06ｨｺ09ｨｨｨｺ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ 01ｨ 08ｨ ｨｺｨｰ0208ｨｨ09ｨｰｨｨｨｺｨｨ 05ｨｰｨ ｨｪ0605ｨ, ｨｺ06ｨｰ060804ｨｦ 0907060906ｨ 02ｨｪ ｨ 0506ｨｺｨｨ080609ｨ ｨｰｨｹ 0106 3/4 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06ｨｦ ｨｬ06ｨｴｨｪ0609ｨｰｨｨ 0702 ﾂ02ｨｪｨｨ. 06ｨｰ060006 010609ｨｰｨ ｨｰ06 ﾂｨｪ06, ﾂｨｰ06ｨ 04 060905ｨ ｨ ｨｨｨｰｨｹ 0506ｨ 0402 0108ｨｮ00ｨｨ02 ｨｬ02ｨｰｨ ｨ 0605ｨｨ ﾂ0209ｨｺｨｨ 09ｨ 03ｨｪ0402 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ0402 0708060202090904, 070806ｨｰ02ｨｺｨ 06ｨｴｨｨ02 09 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02ｨｬ 010802 + (ｨ 050806ｨ ｨｪ04ｨｦ 0005ｨｨｨｺ0605ｨｨ04, 02ｨｨｨｺ05 080802ｨ 09ｨ, ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬ ｨｰ08ｨｨ0005ｨｨ020208ｨｨ010609 ｨｨ 03ｨｨ08ｨｪ0401 ｨｺｨｨ090506ｨｰ ｨｨ ｨｰ.01.). 87
13010209ｨｬ06ｨｰ0807 ｨｪｨ 09ｨ 03ｨｪ0609ｨｰｨｹ 090607080609ｨ 07080600ｨｨ05ｨ ｨｺｨｰｨｨｨｺｨｨ ｨｨ 0502 ﾂ02ｨｪｨｨ07 ｨ 05ｨｺ06000605ｨｹｨｪ06ｨｦ ｨ 06050204ｨｪｨｨ ｨｨ ｨ 0600ｨ ｨｰ04ｨｦ ｨｨ09ｨｰ0608ｨｨ ﾂ0209ｨｺｨｨｨｦ 060704ｨｰ, 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ06ｨｴｨｨｨｦ 06 04ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ06 ｨ 0605ｨｹ0302ｨｦ ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｨ ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ07 ｨ 05ｨｺ06000605ｨｹｨｪ0401 ｨｪｨ 07ｨｨｨｰｨｺ0609, 090601020803ｨ ｨｴｨｨ01 0708ｨｨ080601ｨｪ0402 ｨｺ06ｨｬ070502ｨｺ0904 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 (09ｨｨｨｪ060008ｨ 01ｨｪ0602 09ｨｨｨｪ06, 07ｨ 0506 ﾂｨｪ04ｨｦ 09ｨｨ0108), 08ｨ ｨ 06ｨｰ, 06090902ｨｴｨ 06ｨｴｨｨ01 ｨｮ ﾂｨ 09ｨｰｨｨ02 05ｨｰｨｨ01 0902ｨｴ0209ｨｰ09 09 ｨｺ06080802ｨｺｨｰｨｨ080609ｨｺ02 ｨｪｨ 08ｨｮ0302ｨｪｨｨｨｦ, 0904040409ｨ 02ｨｬ0401 ｨ 05ｨｺ0600060502ｨｬ, 0709ｨｪ06 ｨｪ02010609ｨｰｨ ｨｰ06 ﾂｨｪ06. 0201ｨｪｨ ｨｺ06 01ｨ 0302 ｨｨｨｬ0206ｨｴｨｨ020907 00ｨ ｨｺｨｰ04 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ06ｨｰ 06ｨ ｨ ｨｺｨｰｨｨ09ｨｪ06ｨｬ 09ｨｺ0506 ﾂ02ｨｪｨｨｨｨ 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬ ｨ 05ｨｺ0600060507 09 060800ｨ ｨｪｨｨ04ｨｬ02 ﾂ0205060902ｨｺｨ ｨｨ 03ｨｨ0906ｨｰｨｪ0401. 06ｨ ｨｺ, ｨｪｨ ｨ 05ｨｺ06000605ｨｹｨｪ06ｨｦ ｨｬ06010205ｨｨ 070608ｨ 0302ｨｪｨｨ07 0702 ﾂ02ｨｪｨｨ (010806ｨｪｨｨ ﾂ0209ｨｺｨｨｨｦ 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ) ｨ 040506 0706ｨｺｨ 04ｨ ｨｪ06, ﾂｨｰ06 ｨｺ06ｨｬ070502ｨｺ09 070605ｨｨ0002ｨｪ06050609 000802ｨ ｨｪ02ｨｦ (06090209ｨ 07 ﾂｨ 09ｨｰｨｹ 0906020902ｨｰｨｨ07, 06090906ｨ 06030102ｨｪｨｪｨ 07 06ｨｰ 07000601) 09ｨｨｨｪ060008ｨ 01ｨ, 090601020803ｨ ｨｴｨｨｨｦ 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨ ｨｺｨｰｨｨ09ｨｪ060006 ｨｪｨ ﾂｨ 05ｨ ｨｺ06ｨｬ070502ｨｺ09 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, ｨｪ0608ｨｬｨ 05ｨｨ040609ｨ 05 0706ｨｺｨ 04ｨ ｨｰ0205ｨｨ 05ｨｨ07ｨｨ01ｨｪ060006 06ｨ ｨｬ02ｨｪｨ [2]. 02ｨｰｨｬ02 ﾂｨ 05ｨｨ 09060909ｨｰｨ ｨｪ06090502ｨｪｨｨ02 05ｨｨ0706ｨｰ080607ｨｪ06ｨｦ ｨｨ 0500ｨｨ080606ｨ 08ｨ 04ｨｮ06ｨｴ02ｨｦ 00ｨｮｨｪｨｺ02ｨｨｨｨ 0702 ﾂ02ｨｪｨｨ ｨｨ, ｨｺｨ ｨｺ 0905020109ｨｰ09ｨｨ02 05ｨｰ060006, 070806020209090609 ｨｺｨ ｨｰｨ ｨ 0605ｨｨ04ｨｬｨ ｨｨ ｨ ｨｨ0609ｨｨｨｪｨｰ0204ｨ 05ｨｨ0706070806ｨｰ02ｨｨ010609. 030605ｨｨ0002ｨｪ060504 09ｨｨｨｪ060008ｨ 01ｨ 0904040409ｨ 05ｨｨ 09ｨｪｨｨ0302ｨｪｨｨ02 090601020803ｨ ｨｪｨｨ07 ｨｰ08ｨｨｨ 02ｨｨ050005ｨｨ020208ｨｨｨｪ0609 ｨｨ 090906ｨ 0601ｨｪ060006 0106050209ｨｰ0208ｨｨｨｪｨ 09 0702 ﾂ02ｨｪｨｨ ｨｺ080409. 01ｨ ｨ 050601ｨ 05ｨ 09ｨｹ ｨｨ ﾂ02ｨｰｨｺ06 090408ｨ 0302ｨｪｨｪｨ 07 ｨｺ06080802ｨｺ02ｨｨ07 06ｨｺｨｨ0905ｨｨｨｰ0205ｨｹｨｪ06-09060909ｨｰｨ ｨｪ0609ｨｨｨｰ0205ｨｹｨｪ060006 08ｨ 09ｨｪ06090209ｨｨ07, ｨｪｨ 08ｨｮ03ｨ 02ｨｬ060006 09 0708060202090902 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬｨ 05ｨｰｨ ｨｪ0605ｨ. 010608ｨｬｨ 05ｨｨ040609ｨ 050609ｨｹ 090601020803ｨ ｨｪｨｨ02 06ｨｺｨｨ090502ｨｪｨｪ0401 000608ｨｬ ｨｺ06000208ｨｬ02ｨｪｨｰ0609 010802 + ｨｨ 01080208 + ｨｨ ｨｮ090205ｨｨ ﾂｨｨ09ｨ 050609ｨｹ 090606ｨｰｨｪ060302ｨｪｨｨ02 010802+/01080201, 090905020109ｨｰ09ｨｨ02 ﾂ020006 070806ｨｨ09010601ｨｨ05ｨ 0802ｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ07 010200ｨｨ0108060002ｨｪｨ 0404 ｨｨ 09ｨｪ07ｨｰｨｨ02 ｨｰｨｺｨ ｨｪ020906ｨｦ 00ｨｨ0706ｨｺ09ｨｨｨｨ [2]. 03060401ｨｪ0202 09 ｨｪｨ 0302ｨｦ 05ｨ ｨ 0608ｨ ｨｰ0608ｨｨｨｨ ｨ 0405ｨｨ 070605ｨｮ ﾂ02ｨｪ04 07080207ｨ 08ｨ ｨｰ04 ｨｨ04 000802ｨ ｨｪ02ｨｦ 01ｨ 05ｨｹｨｪ02090609ｨｰ06 ﾂｨｪ060006 09ｨｨｨｪ060008ｨ 01ｨ (Vitis amurensis), ｨｺｨ 05ｨｨｨｪ04 (Viburnum opuli), 05ｨｨｨｬ06ｨｪｨｪｨｨｨｺｨ ｨｺｨｨｨｰｨ ｨｦ09ｨｺ060006 (Schizandra chinensis), 090601020803ｨ ｨｴｨｨ02 09 ｨｺｨ ﾂ0209ｨｰ0902 ｨ ｨｺｨｰｨｨ09ｨｪ060006 ｨｪｨ ﾂｨ 05ｨ ｨｺ06ｨｬ070502ｨｺ09 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609, 0506ｨｺｨ 05ｨｨ04ｨｮ06ｨｴｨｨｨｦ 09 0902ｨ 02 0106 80% 06ｨ ｨｴ02ｨｦ ｨ ｨｪｨｰｨｨ06ｨｺ09ｨｨ01ｨ ｨｪｨｰｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ0401 ｨｨ04090502 ﾂ02ｨｪｨｨｨｦ [4]. 00 ｨｮ09050609ｨｨ0701 0609ｨｰ0806ｨｦ ｨ 05ｨｺ06000605ｨｹｨｪ06ｨｦ ｨｨｨｪｨｰ06ｨｺ09ｨｨｨｺｨ 02ｨｨｨｨ ｨ 040506 06ｨ ｨｪｨ 08ｨｮ0302ｨｪ06 0708ｨｺ06 090408ｨ 0302ｨｪｨｪ0602 000207ｨ ｨｰ06070806ｨｰ02ｨｺｨｰ0608ｨｪ0602 0102ｨｦ09ｨｰ09ｨｨ02 09090201 ｨｮ0706ｨｬ07ｨｪｨｮｨｰ0401 07080207ｨ 08ｨ ｨｰ0609, ｨｺ06ｨｰ06080602 090408ｨ 03ｨ 050609ｨｹ 09 ｨｪ0608ｨｬｨ 05ｨｨ04ｨ 02ｨｨｨｨ ｨ ｨｨ0601ｨｨｨｬｨｨ ﾂ0209ｨｺｨｨ01 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 05ｨｨ07ｨｨ01ｨｪ060006 ｨｨ ｨｮ000502090601ｨｪ060006 06ｨ ｨｬ02ｨｪｨ, 09ｨｺ0506 ﾂｨ 07 ｨｮ08060902ｨｪｨｹ ｨｪ02ｨｦｨｰ08ｨ 05ｨｹｨｪ0401 ｨｨ 0706050708ｨｪ0401 05ｨｨ07ｨｨ010609, 000609000605ｨｨ07ｨｨ01ｨｪ0401 0008ｨ ｨｺ02ｨｨｨｦ ｨｨ 03ｨｨ08ｨｪ06ｨｺｨｨ090506ｨｰｨｪ04ｨｦ 090609ｨｰｨ 09 ｨｬ02ｨｬｨ 08ｨ ｨｪ 000207ｨ ｨｰ0602ｨｨｨｰ0609. 02ｨｰｨｬ02 ﾂ02ｨｪ04 09060909ｨｰｨ ｨｪ06090502ｨｪｨｨ02 090601020803ｨ ｨｪｨｨ07 06ｨｺｨｨ090502ｨｪｨｪ0401 000608ｨｬ ｨｺ06000208ｨｬ02ｨｪｨｰ0609 010802 + ｨｨ 01080208 +, ｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ07 070806020209090609 000506ｨｺ06ｨｪ02060002ｨｪ0204ｨ ｨｨ 0005ｨｨｨｺ0605ｨｨ04ｨ [5]. 00 ｨｰ06 0302 090802ｨｬ07 ｨｪ02ｨｺ06ｨｰ06080402 ｨ 09ｨｰ060804 ｨｪ02 06ｨ ｨｪｨ 08ｨｮ03ｨｨ05ｨｨ 0905ｨｨ07ｨｪｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ 0706ｨｺｨ 04ｨ ｨｰ0205ｨｨ 05ｨｨ07ｨｨ01ｨｪ060006 06ｨ ｨｬ02ｨｪｨ 0708ｨｨ 010806ｨｪｨｨ ﾂ0209ｨｺ06ｨｦ ｨ 05ｨｺ06000605ｨｨ04ｨ 02ｨｨｨｨ, 06ｨｰｨｬ02 ﾂｨ 07, ｨｰ02ｨｬ ｨｪ02 ｨｬ02ｨｪ0202, 04ｨ ｨｴｨｨｨｰｨｪ0602 0905ｨｨ07ｨｪｨｨ02 ｨｰｨ ｨｺ06090401 ｨｪｨ ｨｬ06080006050600ｨｨ ﾂ0209ｨｺｨｨ02 0706ｨｺｨ 04ｨ ｨｰ0205ｨｨ 0702 ﾂ02ｨｪｨｨ [44]. 0201ｨｪｨｨｨｬ ｨｨ04 ｨｪｨ ｨｨｨ 06050202 ｨｨｨｪｨｰ02080209ｨｪ0401 00ｨ ｨｺｨｰ0609 090604ｨｬ0603ｨｪ060006 ｨｮ ﾂｨ 09ｨｰｨｨ07 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 0708060202090902 ｨｬ02ｨｰｨ ｨ 0605ｨｨ04ｨｬｨ 05ｨｰｨ ｨｪ0605ｨ 0709050702ｨｰ0907 020006 0905ｨｨ07ｨｪｨｨ02 ｨｪｨ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 05ｨｰｨ ｨｪ060506ｨｺｨｨ09050706ｨｴｨｨ01 000208ｨｬ02ｨｪｨｰ0609. 06ｨ ｨｺ, 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰｨ 01 in vivo 070601 0905ｨｨ07ｨｪｨｨ02ｨｬ 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 ｨｪｨ ｨ 050601ｨ 05ｨ 09ｨｹ ｨ ｨｺｨｰｨｨ09ｨ 02ｨｨ07 080201ｨｮｨｺｨｰｨ 04ｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ ｨ 05ｨｺ06000605ｨｹ010200ｨｨ0108060002ｨｪｨ 0404 ｨｺｨ ｨｺ 0708ｨｨ 0105ｨｨｨｰ0205ｨｹｨｪ06ｨｦ ｨ 05ｨｺ06000605ｨｨ04ｨ 02ｨｨｨｨ 03ｨｨ0906ｨｰｨｪ0401, ｨｰｨ ｨｺ ｨｨ 0708ｨｨ 0601ｨｪ06ｨｺ08ｨ ｨｰｨｪ06ｨｬ 0708ｨｨ02ｨｬ02 ｨ 05ｨｺ0600060507 04010608060904ｨｬｨｨ ｨｨ090704ｨｰｨｮ02ｨｬ04ｨｬｨｨ [3]. 08ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨ 05ｨｹ010200ｨｨ01010200ｨｨ0108060002ｨｪｨ 0404 09 ｨｪｨｨ04ｨｺ06ｨｦ 08 m 09060108ｨ ｨｪ0705ｨ 09ｨｹ ｨｪｨ ｨｮ080609ｨｪ02 ｨｨｨｪｨｰｨ ｨｺｨｰｨｪ060006 ｨｺ06ｨｪｨｰ08060507. 06ｨｰ06 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ02ｨｰ 06 04ｨ ｨｴｨｨｨｰ02 0601ｨｪ06ｨｦ ｨｨ04 09ｨ 03ｨｪ02ｨｦ03ｨｨ01 00ｨｨ04ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ01 00ｨｮｨｪｨｺ02ｨｨｨｦ ｨ 05ｨｺ06000605ｨｹ010200ｨｨ0108060002ｨｪｨ 0404 (09060909ｨｰｨ ｨｪｨ 0905ｨｨ09ｨ ｨｰｨｹ ｨ 0202ｨｰｨ 05ｨｹ010200ｨｨ01 0106 05ｨｰｨ ｨｪ0605ｨ ), 09 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 ﾂ020006 07060101020803ｨｨ09ｨ 02ｨｰ0907 ｨｪｨｨ04ｨｺｨ 07 ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ07 ｨ 0202ｨｰｨ 05ｨｹ010200ｨｨ01ｨ ｨC 0609ｨｪ0609ｨｪ060006 00ｨ ｨｺｨｰ0608ｨ 07ｨ ｨｰ060002ｨｪｨｪ0609ｨｰｨｨ 070608ｨ 03ｨ 06ｨｴ020006 0102ｨｦ09ｨｰ09ｨｨ07 05ｨｰｨ ｨｪ0605ｨ [3]. 02ｨ 040608 ｨｨｨｬ0206ｨｴｨｨ010907 01ｨ ｨｪｨｪ0401 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ02ｨｰ 06 ｨｰ06ｨｬ, ﾂｨｰ06 ｨｺ06ｨｬ070502ｨｺ0904 0605ｨｨ0006ｨｬ0208ｨｪ0401 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 0709050706ｨｰ0907 09040906ｨｺ06ｨ ｨｺｨｰｨｨ09ｨｪ04ｨｬｨｨ 09060201ｨｨｨｪ02ｨｪｨｨ07ｨｬｨｨ, 06ｨ 05ｨ 01ｨ 06ｨｴｨｨｨｬｨｨ 03ｨｨ0806ｨｺｨｨｨｬ 090702ｨｺｨｰ0806ｨｬ ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ, ｨｺ06ｨｰ0608ｨ 07 060708020102050702ｨｰ0907 ｨｨ01 070605ｨｨ0002ｨｪ0605ｨｹｨｪ06ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ0806ｨｦ. 00040906ｨｺ0602 090601020803ｨ ｨｪｨｨ02 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪ0609 09 08ｨ 09ｨｰ02ｨｪｨｨ0701, 0008ｨｮｨｺｨｰｨ 01, 07050601ｨ 01 ｨｨ 07000601ｨ 01, ｨｰ08ｨ 01ｨｨ02ｨｨ06ｨｪｨｪ06 ｨｨ09070605ｨｹ04ｨｮ02ｨｬ0401 09 07ｨｨｨｴｨｮ ﾂ0205060902ｨｺ06ｨｬ, 060708020102050702ｨｰ ｨｨ01 ｨｺｨ ｨｺ ｨｪｨ ｨｨｨ 06050202 ｨｮ0706ｨｰ0802ｨ 050702ｨｬ04ｨｦ 09ｨｨ01 08ｨ 09ｨｰｨｨｨｰ0205ｨｹｨｪ0401 070605ｨｨ0002ｨｪ0605ｨｹｨｪ0401 09060201ｨｨｨｪ02ｨｪｨｨｨｦ. 030605ｨｮ ﾂ02ｨｪｨｪ0402 01ｨ ｨｪｨｪ0402 06 ｨｺ06080802ｨｺ02ｨｨｨｨ 070806ｨ ｨｪｨｰ0602ｨｨｨ ｨｪｨｨ01ｨｨｨｪｨ ｨｬｨｨ ｨｬ02ｨｰｨ ｨ 0605ｨｨ ﾂ0209ｨｺｨｨ01 ｨｪｨ 08ｨｮ0302ｨｪｨｨｨｦ 0708ｨｨ ｨ 05ｨｺ06000605ｨｹｨｪ06ｨｦ ｨｨｨｪｨｰ06ｨｺ09ｨｨｨｺｨ 02ｨｨｨｨ 01ｨ 06ｨｰ 0609ｨｪ0609ｨ ｨｪｨｨ02 08ｨ 0909ｨｬｨ ｨｰ08ｨｨ09ｨ ｨｰｨｹ 090604ｨｬ0603ｨｪ0609ｨｰｨｹ ｨｨ01 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ07 09 09ｨｨ09ｨｰ02ｨｬ02 07080600ｨｨ05ｨ ｨｺｨｰｨｨｨｺｨｨ ｨｨ 0802ｨ ｨ ｨｨ05ｨｨｨｰｨ 02ｨｨｨｨ 07ｨ ｨｰ0600ｨｨ04ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｨ01 090609ｨｰ0607ｨｪｨｨｨｦ, 08ｨ 0409ｨｨ09ｨ 06ｨｴｨｨ010907 09 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 ｨｮ0706ｨｰ0802ｨ 0502ｨｪｨｨ07 ｨ 05ｨｺ0600060507. 88
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