13000806030406080904 010807 ﾁ0102-030408080606 ﾁ0305080207 0802010803040301000606 05 00030402070108040202010400 07 ﾁ080506060300 0008050804020005080603 ﾁ0603010608. 010307040202080608090500020902010608. 030806020902010608 050306 ﾁ0806080603 12ｨC14 06ｨｺｨｰ07ｨ 0807 2011 000601ｨ, 00. 05ｨｮ01ｨ ｨｺ
132011, ｨｰ06ｨｬ 14, 014 ﾂ.2 (56) 0608000406 ﾁ0305080607 000302060802-09060209020106 ﾁ0305080607 00030506010608 070208 617.735-02:616.379-008.64]-085.357:577.175.53 08 03. 08. 0902040102ｨｰｨｺ06, 02. 00. 05ｨ 09060506ｨｺｨ, 06. 01. 02060903ｨｮｨｺ, 2011. 0608050303040600030106080905010203 060505090302020008010603 080804000808020806010306060806 06 090305020308050102050606 0601060408050809030408090501020102 02030302010604020008010608 06040608000006010209020108 080003060201060208 03. 08. 0902040102ｨｰｨｺ06, 02. 00. 05ｨ 09060506ｨｺｨ, 06. 01. 02060903ｨｮｨｺ 09ｨ 08ｨｹｨｺ060909ｨｺｨｨｨｦ ｨｪｨ 02ｨｨ06ｨｪｨ 05ｨｹｨｪ04ｨｦ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺｨｨｨｦ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ EXPERIMENTAL RESEARCH OF PHARMAKOKINETICS AND SAFETY OF INTRAS05LERAL DEPOSITIONG OF TRIAMCINOLONE A05ETONIDE P. A. Bezdetko, T. N. Dovzhuk, O. V. Zavoloka Safety of the inrtascleral deposition of 40 mgs of crystals triamcinolone acetonide was well-proven experimentally as a result of the conducted researcheson 40 crawls for intraocular tissues on such indexes, as ophthalmotonus, degree of cataract and the inflammatory reaction of the eye on the operation. Concentration of triamcinolone acetonide in blood plasma, intraocular liquid, and intraocular tissues (vitreous body, retinochoroid layer) by the method of liquid chromatography was determined to research pharmacokinetics in 3 hour, 1, 3, 7, 14 days and 1, 2, 3, 6, 7 months after an injection. Triamcinolone acetonide in the determined concentration had been in the retinochoroid layer for 6 months, in the vitreous body and intraocular liquid for 3 months, in the blood plasma for 7 days. 03080503030406000301060809050103 0202050905020403010108 080804000808020805010306060806 0608 0903050303 ﾁ0102050605 0501060408050809030408090501020102 0203030201070008010108 06040608000006010209020107 080003060201050207 03. 08. 0902040106ｨｰｨｺ06, 02. 00. 05ｨ 09060506ｨｺｨ, 06. 00. 02060903ｨｮｨｺ 00 080204ｨｮ05ｨｹｨｰｨ ｨｰ06 07080609020102ｨｪｨｨ01 0106090506010302ｨｪｨｹ 02ｨｺ09070208ｨｨｨｬ02ｨｪｨｰｨ 05ｨｹｨｪ06 ｨｪｨ 40 ｨｺ0806050701 ｨ ｨｮ05ｨ 0106ｨｺｨ 04ｨ ｨｪｨ ｨ 02040702 ﾂｨｪ0609ｨｰｨｹ 06ｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 01020706ｨｪｨｮ09ｨ ｨｪｨｪ07 40 ｨｬ00 ｨｺ08ｨｨ09ｨｰｨ 050609 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨｮ ｨ 0202ｨｰ06ｨｪ0601ｨｮ 010507 09ｨｪｨｮｨｰ080603ｨｪｨｹ0606 ﾂｨｪｨｨ01 ｨｰｨｺｨ ｨｪｨｨｨｪ 0706 ｨｰｨ ｨｺｨｨｨｬ 0609ｨｪ0609ｨｪｨｨｨｬ 0706ｨｺｨ 04ｨｪｨｨｨｺｨ ｨｬ, 07ｨｺ 09ｨｪｨｮｨｰ080603ｨｪｨｹ0606 ﾂｨｪｨｨｨｦ ｨｰｨｨ09ｨｺ, 09ｨｰｨｮ0706ｨｪｨｹ 0706ｨｬｨｮｨｰｨｪ06ｨｪｨｪ07 ｨｺ08ｨｨ03ｨｰｨ 05ｨｨｨｺｨ ｨｰｨ 09ｨｨ08ｨ 04ｨｪ0609ｨｰ06 04ｨ 07ｨ 05ｨｹｨｪ0607 0802ｨ ｨｺ020607 06ｨｺｨ ｨｪｨ 06070208ｨ 020606. 020507 0106090506010302ｨｪｨｪ07 00ｨ 08ｨｬｨ ｨｺ06ｨｺ06ｨｪ02ｨｰｨｨｨｺｨｨ 09ｨｨ04ｨｪｨ ﾂｨ 05ｨｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 020606 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨｮ ｨ 0202ｨｰ06ｨｪ0601ｨｮ 09 0705ｨ 04ｨｬ06 ｨｺ08060906, 09ｨｪｨｮｨｰ080603ｨｪｨｹ0606 ﾂｨｪ06ｨｦ 080601ｨｨｨｪ06, ｨ ｨｰｨ ｨｺ0603 ｨｮ 090601 090207ｨ 080609ｨ ｨｪｨｨ01 ｨｰｨｺｨ ｨｪｨｨｨｪｨ 01 (09ｨｺ050609ｨｨ01ｨｪ06ｨｬｨｮ ｨｰ060506, 0802ｨｰｨｨｨｪ06010608ｨｨ060601ｨ 05ｨｹｨｪ06ｨｬｨｮ 03ｨ 0806) ｨｬ02ｨｰ060106ｨｬ 080601ｨｺ0607 010806ｨｬｨ ｨｰ060008ｨ 000607 ﾂ02080204 3 000605ｨｨｨｪｨｨ, 1, 3, 7, 14 01ｨｪ0609 ｨｰｨ 1, 2, 3, 6, 7 ｨｬ060907020609 0706090507 06ｨｪ'02ｨｺ020607. 07 09ｨｨ04ｨｪｨ ﾂｨ 02ｨｬ06ｨｦ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 020607 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪ ｨ 0202ｨｰ06ｨｪ0601 04ｨｪｨ 010601ｨｨ090907 09 0802ｨｰｨｨｨｪ06010608ｨｨ060601ｨ 05ｨｹｨｪ06ｨｬｨｮ 03ｨ 0806 6 ｨｬ060907020609, 09 09ｨｺ05ｨｨ09ｨｰ06ｨｬｨｮ ｨｰ060506 ｨｰｨ 09ｨｪｨｮｨｰ080603ｨｪｨｹ0606 ﾂｨｪ06ｨｦ 080601ｨｨｨｪ06 ｨC 3 ｨｬ0609070206, 09 0705ｨ 04ｨｬ06 ｨｺ08060906 ｨC 7 01ｨｪ0609. 080506 ﾂ02090402 09050609ｨ : ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01, ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ04ｨｦ 0907060906ｨ 0909020102ｨｪｨｨ07, 00ｨ 08ｨｬｨ ｨｺ06-ｨｺｨｨｨｪ02ｨｰｨｨｨｺｨ, 0802ｨｰｨｨｨｪ06010608ｨｨ06ｨｨ01ｨ 05ｨｹｨｪ04ｨｦ 090506ｨｦ, 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ0602 ｨｰ020506, 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪｨ 07 03ｨｨ01ｨｺ0609ｨｰｨｹ, 0705ｨ 04ｨｬｨ ｨｺ080609ｨｨ, 0609050603ｨｪ02ｨｪｨｨ07. 0308ｨｨｨｪｨｨｨｬｨ 07 0906 09ｨｪｨｨｨｬｨ ｨｪｨｨ02, ﾂｨｰ06 0005ｨ 04 04ｨ ｨｪｨｨｨｬｨ 02ｨｰ 0,01 % 070605ｨｪ060006 06ｨ ｨｲ02ｨｬｨ ｨｰ0205ｨ, ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ0906 0600ｨｰｨ 05ｨｹｨｬ060506000609 070802010706 ﾂｨｨｨｰｨ 06ｨｰ 00ｨ 01080209ｨｪｨｮ0603 010609ｨｰｨ 09ｨｺｨｮ 0502ｨｺｨ 0809ｨｰ0902ｨｪｨｪ0401 07080207ｨ 08ｨ ｨｰ0609. 00 05ｨｨｨｰ0208ｨ ｨｰｨｮ0802 070609050201ｨｪｨｨ01 0502ｨｰ 07060709ｨｨ050907 ｨｰ0208ｨｬｨｨｨｪ 0000ｨ 08ｨｬｨ ｨｺ0601ｨｨ08ｨｮ0800ｨｨ0703 [13, 14]. 0608ｨ ｨｪ0909ｨｺ050208ｨ 05ｨｹｨｪ04ｨｦ 07ｨｮｨｰｨｹ 0909020102ｨｪｨｨ07 09 ｨｪｨ 09ｨｰ0607ｨｴ0202 090802ｨｬ07 ｨｨ09070605ｨｹ04ｨｮ02ｨｰ0907 0708ｨｨ 09ｨｮｨ ｨｰ02ｨｪ06ｨｪ06090401 ｨｨｨｪｨｲ02ｨｺ02ｨｨ0701 ｨC ｨ 02040607ｨ 09ｨｪ06ｨｬ ｨｬｨ 0506ｨｨｨｪ09ｨ 04ｨｨ09ｨｪ06ｨｬ ｨｬ02ｨｰ060102, ｨｪ02 ｨｰ0802ｨ ｨｮ06ｨｴ02ｨｬ 070208000608ｨ 02ｨｨｨｨ 0005ｨ 04ｨｪ060006 07ｨ 0506ｨｺｨ. 0201ｨｪｨ ｨｺ06 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 ｨｨｨｪｨｰ08ｨ 09ｨｨｨｰ0802ｨ 05ｨｹｨｪ04ｨｬｨｨ ｨｨｨｪｨｲ02ｨｺ02ｨｨ07ｨｬｨｨ 06ｨｰｨｬ02 ﾂｨ 02ｨｰ0907 ｨｪｨｨ04ｨｺｨ 07 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ 09ｨｮｨ ｨｰ02ｨｪ06ｨｪ0609060006 0909020102ｨｪｨｨ07 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ (0608) [10, 11], ﾂｨｰ06, 0706 ｨｬｨｪ02ｨｪｨｨ06 ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ09ｨ ｨｨ09090502010609ｨ ｨｰ020502ｨｦ, 09090704ｨ ｨｪ06 09 ｨ 0409ｨｰ0806ｨｦ ｨ ｨ 090608ｨ 02ｨｨ02ｨｦ 07080207ｨ 08ｨ ｨｰｨ ｨｺ06ｨｪｨｲ06ｨｪｨｺｨｰｨｨ09ｨ 05ｨｹｨｪ04ｨｬｨｨ 090609ｨｮ01ｨ ｨｬｨｨ [2, 3, 7, 8, 12]. 00 05ｨｨｨｰ0208ｨ ｨｰｨｮ0802 09 070609050201ｨｪ0202 090802ｨｬ07 09ｨｰｨ 05ｨｨ 070607090507ｨｰｨｹ0907 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨ 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ0401 ｨｨｨｬ0705ｨ ｨｪｨｰｨ ｨｰ0609 09 0608 [1]. 05ｨｺ050208ｨ 0709050702ｨｰ0907 ｨ 0204090609ｨｮ01ｨｨ09ｨｰ06ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ0806ｨｦ, 09 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 ﾂ020006 ｨｪｨｨ090205ｨｨ08ｨｮ02ｨｰ0907 05000002ｨｺｨｰ ｨ ｨ 090608ｨ 02ｨｨｨｨ 07080207ｨ 08ｨ ｨｰｨ 05ｨｨｨｬ00ｨ ｨｰｨｨ ﾂ0209ｨｺｨｨｨｬｨｨ ｨｨ ｨｺ08060902ｨｪ0609ｨｪ04ｨｬｨｨ 090609ｨｮ01ｨ ｨｬｨｨ 0608ｨ ｨｨｨｰ04 ｨｨ ｨｺ06ｨｪｨｲ06ｨｪｨｺｨｰｨｨ0904. 080806ｨｬ02 ｨｰ060006 ｨｨ04090209ｨｰｨｪ06, ﾂｨｰ06 ｨｺ06050000ｨｨ02ｨｨ02ｨｪｨｰ 070806ｨｪｨｨ02ｨ 02ｨｬ0609ｨｰｨｨ 09ｨｺ05020804 0706090403ｨ 02ｨｰ0907 09 0005ｨｮｨ ｨｨｨｪ06ｨｦ ｨｨ04-04ｨ 0202 090506ｨｨ09ｨｰ06ｨｦ 09ｨｰ08ｨｮｨｺｨｰｨｮ0804 [9]. 06ｨｰｨｨ ｨ ｨｪｨ ｨｰ06ｨｬｨｨ ﾂ0209ｨｺｨｨ02 070802010706090405ｨｺｨｨ ｨｬ0600ｨｮｨｰ 06070802010205ｨｨｨｰｨｹ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ04ｨｦ 07ｨｮｨｰｨｹ 0909020102ｨｪｨｨ07 0608 ｨ 05ｨｹｨｰ0208ｨｪｨ ｨｰｨｨ0906ｨｦ ｨ 06050202 0607ｨ 09ｨｪ06ｨｬｨｮ 09 0705ｨ ｨｪ02 0609050603ｨｪ02ｨｪｨｨｨｦ ｨｨｨｪｨｰ08ｨ 09ｨｨｨｰ0802ｨ 05ｨｹｨｪ06ｨｬｨｮ 07ｨｮｨｰｨｨ. 0604090209ｨｰｨｪ06, ﾂｨｰ06 ｨｬｨ 050608ｨ 09ｨｰ090608ｨｨｨｬ0402 ｨｺ08ｨｨ09ｨｰｨ 050504 0608 ｨｨｨｬ0206ｨｰ ｨ 06050202 ｨｬ02010502ｨｪｨｪｨｮ06 ｨｪ0608ｨｬｨｮ 0904090906ｨ 06030102ｨｪｨｨ07, ﾂ02ｨｬ 0906010608ｨ 09ｨｰ090608ｨｨｨｬ0402 ｨｺ06ｨｬ0706ｨｪ02ｨｪｨｰ04, ﾂｨｰ06 07080201070605ｨ 00ｨ 02ｨｰ ｨ 06050202 07080601060503ｨｨｨｰ0205ｨｹｨｪ0602 0102ｨｦ09ｨｰ09ｨｨ02 07080207ｨ 08ｨ ｨｰｨ [4, 5]. 030605ｨｰ06ｨｬｨｮ ｨｮ ｨｪｨ 09 090604ｨｪｨｨｨｺ05ｨ ｨｨ010207 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0909020102ｨｪｨｨ07 ｨｺ08ｨｨ09ｨｰｨ 05050609 0608 09 09040906ｨｺ06ｨｦ 01060402 (40 ｨｬ00), ﾂｨｰ06 ｨｬ060302ｨｰ 09ｨｰｨ ｨｰｨｹ ｨ 05ｨｹｨｰ0208ｨｪｨ ｨｰｨｨ09ｨｪ04ｨｬ 07ｨｮｨｰ02ｨｬ 010609ｨｰｨ 09ｨｺｨｨ 07080207ｨ 08ｨ ｨｰｨ ｨｺ 04ｨ 01ｨｪ02ｨｬｨｮ 0706050609ｨｮ 0005ｨ 04ｨ. 000205ｨｹ ｨｨ09090502010609ｨ ｨｪｨｨ07: 070609040302ｨｪｨｨ02 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｨ 010609ｨｰｨ 09ｨｺｨｨ 0608 ｨｺ 04ｨ 01ｨｪ02ｨｬｨｮ 0706050609ｨｮ 0005ｨ 04ｨ 07ｨｮｨｰ02ｨｬ 08ｨ 0408ｨ ｨ 06ｨｰｨｺｨｨ ｨｪ0609060006 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0907060906ｨ ｨ 0909020102ｨｪｨｨ07, ｨ ｨｰｨ ｨｺ0302 ｨ ｨｪｨ 05ｨｨ04ｨ 00ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨｨｺｨｨ ｨｨ ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｨ ｨｨ09-184
1302 04 06 01 06 01 08 09 05 01 04 03 05 06 08 06 05 06 09050201ｨｮ02ｨｬ060006 07080207ｨ 08ｨ ｨｰｨ 0708ｨｨ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨｨｨ 0708020105060302ｨｪｨｪ060006 0907060906ｨ ｨ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02. 000806030406080904 06 000306020204 06ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ ｨ 0405 0904070605ｨｪ02ｨｪ ｨｪｨ 40 ｨｺ0806050701 070608060104 01ｨｨｨｪ03ｨｨ0505ｨ 09020906ｨｬ 2-2,5 ｨｺ00, ｨｺ06ｨｰ060804ｨｬ 09 09060408ｨ 09ｨｰ02 5-6 ｨｬ020907020209 ｨｪｨ 0708ｨ 0906ｨｬ 0005ｨ 04ｨｮ ｨ 0405ｨ 070806ｨｨ0409020102ｨｪｨ 06070208ｨ 02ｨｨ07 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0909020102ｨｪｨｨ07 40 ｨｬ00 ｨｺ08ｨｨ09ｨｰｨ 05050609 0608. 09ｨｨ08ｨｮ0800ｨｨ ﾂ0209ｨｺ0602 0502 ﾂ02ｨｪｨｨ02 070806090601ｨｨ050609ｨｹ 09 09ｨｰ0208ｨｨ05ｨｹｨｪ0401 ｨｮ09050609ｨｨ0701 070601 06ｨ ｨｴ02ｨｦ (09/ｨｬ 0909020102ｨｪｨｨ02 0002ｨｺ0902ｨｪｨ 05ｨ 09 01060402 100 ｨｬ00/ｨｺ00 ｨｬｨ 090904 ｨｰ0205ｨ ｨｪｨ 0601ｨｪｨｮ ｨｨｨｪｨｲ02ｨｺ02ｨｨ06) ｨｨ ｨｬ0209ｨｰｨｪ06ｨｦ ｨ ｨｪ0209ｨｰ0204ｨｨ02ｨｦ (0,1 % 0805ｨｺｨ ｨｨｨｪ). 090601 06070208ｨ 02ｨｨｨｨ: 08ｨ 04080204 ｨｺ06ｨｪｨｲ06ｨｪｨｺｨｰｨｨ0904 09 09020801ｨｪ02-ｨｰ02ｨｬ070608ｨ 05ｨｹｨｪ06ｨｬ ｨｺ09ｨ 0108ｨ ｨｪｨｰ02 070609080201ｨｨｨｪ02 ｨｬ020301ｨｮ 09020801ｨｪ02ｨｦ ｨｨ 05ｨ ｨｰ0208ｨ 05ｨｹｨｪ06ｨｦ 070807ｨｬ06ｨｦ ｨｬ04030202ｨｦ 09 5-6 ｨｬｨｬ 06ｨｰ 05ｨｨｨｬｨ ｨ, 06ｨｰ090207ｨ 080609ｨｺｨ 0202 06ｨｰ 09ｨｺ05020804; 04ｨ ｨｰ02ｨｬ 09 0706ｨｬ06ｨｴｨｹ06 ｨｪ0603ｨ -08ｨ 090905ｨ ｨｨ09ｨ ｨｰ020507 0904070605ｨｪ02ｨｪｨｨ02 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 ｨｺｨ 08ｨｬｨ ｨｪｨ 08ｨ 04ｨｬ020806ｨｬ 3013 ｨｬｨｬ, 09 ｨｺ06ｨｰ060804ｨｦ ｨｨｨｬ0705ｨ ｨｪｨｰｨｨ08ｨｮ06ｨｰ ｨｺ08ｨｨ09ｨｰｨ 050504 0608 (40 ｨｬ00). 0808ｨ 07 09ｨｺ05020804 00ｨｨｨｺ09ｨｨ08ｨｮ06ｨｰ ｨｪｨｨｨｰｨｺ06ｨｦ ｨｪ02ｨｦ0506ｨｪ 9/0 (08ｨｨ09. 1). 1 2 3 04ｨｨ09. 1. 090601 06070208ｨ 02ｨｨｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0909020102ｨｪｨｨ07 ｨｺ08ｨｨ09ｨｰｨ 05050609 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ. 0308ｨｨｨｬ02 ﾂｨ ｨｪｨｨ07: 1-08ｨ 04080204 ｨｺ06ｨｪｨｲ06ｨｪｨｺｨｰｨｨ0904 ｨｨ 000608ｨｬｨｨ080609ｨ ｨｪｨｨ02 09ｨｺ050208ｨ 05ｨｹｨｪ060006 ｨｺｨ 08ｨｬｨ ｨｪｨ ; 2-0909020102ｨｪｨｨ02 ｨｺ08ｨｨ09ｨｰｨ 05050609 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ ; 3-00ｨｨｨｺ09ｨ 02ｨｨ07 09ｨｺ050208ｨ 05ｨｹｨｪ060006 ｨｺｨ 08ｨｬｨ ｨｪｨ ｨｮ0405060904ｨｬ 030906ｨｬ 10/0. 020507 070605ｨｮ ﾂ02ｨｪｨｨ07 ｨｺ08ｨｨ09ｨｰｨ 05050609 0608 070806ｨｨ04090601ｨｨ05ｨｨ ｨｮ01ｨ 0502ｨｪｨｨ02 ｨｺ06ｨｪ09020809ｨ ｨｪｨｰｨ (ｨ 02ｨｪ04ｨｨ050609060006 0907ｨｨ08ｨｰｨ ) 0202ｨｪｨｰ08ｨｨ00ｨｮ00ｨｨ080609ｨ ｨｪｨｨ02ｨｬ 09ｨｮ090702ｨｪ04ｨｨｨｨ 0802ｨｪｨ 050600ｨ -40 0607ｨｨ09ｨ ｨｪｨｪ04ｨｬ 08ｨ ｨｪ0202 ｨｬ02ｨｰ060106ｨｬ, 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｺ06ｨｰ0608060006 0106ｨｺｨ 04ｨ ｨｪｨ 0008ｨｮ070706ｨｦ ｨ 09ｨｰ06080609 [5, 6]. 020507 0607080201020502ｨｪｨｨ07 ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｨ 0608 010507 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 09ｨｰ08ｨｮｨｺｨｰｨｮ08 070806090601ｨｨ05ｨｨ ｨｰ06ｨｪ06ｨｬ02ｨｰ08ｨｨ06 0706 00ｨ ｨｺ05ｨ ｨｺ0609ｨｮ, ｨ ｨｨ06ｨｬｨｨｨｺ080609ｨｺ0607ｨｨ06, ｨｪ02070807ｨｬｨｮ06 ｨｨ 070807ｨｬｨｮ06 0600ｨｰｨ 05ｨｹｨｬ0609ｨｺ0607ｨｨ06 ﾂ02080204 7, 14 01ｨｪ02ｨｦ ｨｨ 1, 2, 3, 6, 7 ｨｬ020907020209 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ. 06ｨ ｨｺ0302 060202ｨｪｨｨ09ｨ 05ｨｨ 06ｨ ｨｴ0202 090609ｨｰ0607ｨｪｨｨ02 ｨｨ 070609020102ｨｪｨｨ02 03ｨｨ0906ｨｰｨｪ0401, ｨｨ01 06ｨｰｨｪ060302ｨｪｨｨ02 ｨｺ 020102, ｨｨ04ｨｬ02080705ｨｨ ｨｰ02ｨｬ070208ｨ ｨｰｨｮ08ｨｮ ｨｰ0205ｨ. 020507 ｨｨ09090502010609ｨ ｨｪｨｨ07 00ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨｨｺｨｨ 0608 060708020102050705ｨｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ06 0902ｨｴ0209ｨｰ09ｨ 0906 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ0701 ｨｬ02ｨｰ060106ｨｬ 03ｨｨ01ｨｺ06ｨｦ 010806ｨｬｨ ｨｰ060008ｨ 00ｨｨｨｨ. ﾁ02080204 3 ﾂｨ 09ｨ, 1, 3, 7, 14 01ｨｪ02ｨｦ ｨｨ 1, 2, 3, 6, 7 ｨｬ020907020209 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ ｨｨ0909050201ｨｮ02ｨｬ060006 07080207ｨ 08ｨ ｨｰｨ 09 0706ｨｬ06ｨｴｨｹ06 07020802010604ｨｨ080609ｨｺｨｨ 0702ｨｪｨｰ06ｨ ｨ 08ｨ ｨｨｨｰｨ 05ｨ ｨｪｨ ｨｰ08ｨｨ07 ｨ 040506 ｨｮｨ ｨｨｨｰ06 0706 4 03ｨｨ0906ｨｰｨｪ0401 09 ｨｺｨ 030106ｨｦ 0008ｨｮ070702. 0806ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ07 0608 060708020102050705ｨ 09ｨｹ 09 0705ｨ 04ｨｬ02 ｨｺ080609ｨｨ ｨｨ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ06ｨｦ 03ｨｨ01ｨｺ0609ｨｰｨｨ, ｨ ｨｰｨ ｨｺ0302 09 06ｨｰ090207ｨ 080609ｨ ｨｪ0401 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ0701: 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ06ｨｬ ｨｰ020502 ｨｨ 0802ｨｰｨｨｨｪ06010608ｨｨ06ｨｨ01ｨ 05ｨｹｨｪ06ｨｬ 09050602. 0308ｨｨ 05ｨｰ06ｨｬ ｨｨ09070605ｨｹ040609ｨ 05ｨｨ ｨｮ05ｨｹｨｰ08ｨ 0904070605ｨｪｨｨｨｬ04ｨｦ 03ｨｨ01ｨｺｨｨｨｦ 010806ｨｬｨ ｨｰ060008ｨ 00 (ultra-performance liquid chromatography) 0706 08ｨ ｨｪ0202 0607ｨｨ09ｨ ｨｪｨｪ06ｨｦ ｨｬ02ｨｰ0601ｨｨｨｺ02 [4]. 05ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｮ06 06ｨ 08ｨ ｨ 06ｨｰｨｺｨｮ ｨｬｨ ｨｰ0208ｨｨｨ 05ｨ 070806090601ｨｨ05ｨｨ ｨｬ02ｨｰ0601ｨ ｨｬｨｨ 09ｨ 08ｨｨｨ 02ｨｨ06ｨｪｨｪ06ｨｦ 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨｨｺｨｨ 09 0706ｨｬ06ｨｴｨｹ06 0708060008ｨ ｨｬｨｬｨｪ060006 ｨｺ06ｨｬ07ｨｹ06ｨｰ0208ｨｪ060006 06ｨ 02090702 ﾂ02ｨｪｨｨ07 Microsoft Excel 2000 09 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02ｨｬ 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺ060006 07ｨ ｨｺ02ｨｰｨ 0708060008ｨ ｨｬｨｬ. 04030507090506080604 06 0609 02090507040203010603 0308ｨｨ ｨ ｨｪｨ 05ｨｨ0402 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ060006 01ｨ 090502ｨｪｨｨ07 0706 0706ｨｺｨ 04ｨ ｨｰ020506 0708060202ｨｪｨｰｨｪ060006 06ｨｰｨｪ060302ｨｪｨｨ07 0005ｨ 04 09 0600ｨｰｨ 05ｨｹｨｬ0600ｨｨ070208ｨｰ02ｨｪ04ｨｨ02ｨｦ (09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ04ｨｬ 01ｨ 090502ｨｪｨｨ02ｨｬ 070802090403ｨ 06ｨｴｨｨｨｬ 25 ｨｬｨｬHg) 09 01ｨｨｨｪｨ ｨｬｨｨｨｺ02 ｨｪｨ ｨ 05060102ｨｪｨｨ07 0706090502 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0909020102ｨｪｨｨ07 0608 06070802010205ｨｨ05ｨｨ, ﾂｨｰ06 ｨｮ 09090201 ｨｺ08060502ｨｦ ﾂ02080204 7 ｨｨ 14 01ｨｪ02ｨｦ, ｨ ｨｰｨ ｨｺ0302 6 ｨｨ 7 ｨｬ020907020209 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ 0706ｨｺｨ 04ｨ ｨｰ0205ｨｨ ｨｪ02 070802090403ｨ 05ｨｨ 25 ｨｬｨｬHg. 0201ｨｪｨ ｨｺ06 ﾂ02080204 1, 2 ｨｨ 3 ｨｬ02090702ｨ 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ 09 ｨｪ02ｨｺ06ｨｰ06080401 0005ｨ 04ｨ 01 (1, 2 ｨｨ 1 0005ｨ 04 090606ｨｰ0902ｨｰ090902ｨｪｨｪ06) ｨ 040506 06ｨｰｨｬ02 ﾂ02ｨｪ06 070609040302ｨｪｨｨ02 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ060006 01ｨ 090502ｨｪｨｨ07 ｨ 0605ｨｹ0302 25 ｨｬｨｬHg, 0708ｨｨ- ﾂ02ｨｬ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ02 ｨ ｨｪｨｰｨｨ0005ｨ ｨｮｨｺ06ｨｬｨ ｨｰ0604ｨｪ0401 ｨｬ0209ｨｰｨｪ0401 07080207ｨ 08ｨ ｨｰ0609 0906 09090201 0905ｨｮ ﾂｨ 0701 0708ｨｨ090601ｨｨ0506 ｨｺ 09ｨｰｨ ｨ ｨｨ05ｨｨ04ｨ 02ｨｨｨｨ 0706ｨｺｨ 04ｨ ｨｰ020507, 0005ｨ ｨｮｨｺ06ｨｬｨ ｨｰ0604ｨｪｨ 07 0607ｨｰｨｨ ﾂ0209ｨｺｨ 07 ｨｪ02ｨｦ080607ｨ ｨｰｨｨ07 ｨｪ02 090407090502ｨｪｨ. 02ｨ ｨｴｨｨｨｦ 0706ｨｺｨ 04ｨ ｨｰ0205ｨｹ 0600ｨｰｨ 05ｨｹｨｬ0600ｨｨ070208ｨｰ02ｨｪ04ｨｨｨｨ 04ｨ 090209ｨｹ 070208ｨｨ0601 ｨｪｨ ｨ 05060102ｨｪｨｨ07 090609ｨｰｨ 09050705 25 % (4 0005ｨ 04ｨ ). 08ｨｪｨ 05ｨｨ04ｨｨ08ｨｮ07 ｨｬ0201ｨｨｨ ｨｪｨｮ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ060006 01ｨ 090502ｨｪｨｨ07 09 01ｨｨｨｪｨ ｨｬｨｨｨｺ02 ｨｪｨ ｨ 05060102ｨｪｨｨ07, 06070802010205ｨｨ05ｨｨ 010609ｨｰ06090208ｨｪ0602 070609040302ｨｪｨｨ02 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ ﾂ02080204 1 ｨｬ02090702 (23,5; 17-35) ｨｪｨ 28 % ｨｨ ﾂ02080204 2 ｨｬ02090702ｨ 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ (23,9; 18-38) ｨｪｨ 31 % 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 ｨｰｨ ｨｺ060904ｨｬｨｨ 0106 0502 ﾂ02ｨｪｨｨ07 (18,3; 15-22) (08<0,05). 05ｨｰ020702ｨｪｨｹ 0706ｨｬｨｮｨｰｨｪ02ｨｪｨｨ07 0706 5-ｨ ｨ 05ｨｹｨｪ06ｨｦ 03ｨｺｨ 0502 0906 09090201 ｨｨ0909050201ｨｮ02ｨｬ0401 0905060701 0108ｨｮ09ｨｰｨ 05ｨｨｨｺｨ (09ｨｮｨ ｨｺｨ 0709ｨｮ050708ｨｪ06ｨｬ, 07010208-185
132011, ｨｰ06ｨｬ 14, 014 ﾂ.2 (56) 0608000406 ﾁ0305080607 000302060802-09060209020106 ﾁ0305080607 00030506010608 ｨｪ06ｨｬ, ｨｺ0608ｨｰｨｨｨｺｨ 05ｨｹｨｪ06ｨｬ) ﾂ02080204 7 ｨｬ020907020209 0706090502 0909020102ｨｪｨｨ07 0608 ｨｮ ｨｺ08060502ｨｦ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 ｨｪ02 070802090403ｨ 05ｨ 1 ｨ ｨ 0505ｨ. 05ｨｰ020702ｨｪｨｹ 090408ｨ 0302ｨｪｨｪ0609ｨｰｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0005ｨ 04ｨ ｨｪｨ 06070208ｨ 02ｨｨ06 0706 ｨ ｨ 05ｨｹｨｪ06ｨｦ 09ｨｨ09ｨｰ02ｨｬ02 ﾁ02ｨｪ02060906ｨｦ 03. 00. 0706090502 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0907060906ｨ ｨ 0909020102ｨｪｨｨ07 0608 ｨｰ0605ｨｹｨｺ06 09 0601ｨｪ06ｨｬ 090806ｨｺ02 ｨｪｨ ｨ 05060102ｨｪｨｨ07 ( ﾂ02080204 7 01ｨｪ02ｨｦ 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ) ｨ 0405ｨ 09040302 0 ｨ ｨ 05050609, 0106ｨｰ07 ｨｨ ｨｪ02 070802090403ｨ 05ｨ 1 ｨ ｨ 0505, 090609ｨｰｨ 09050705ｨ 0,39 ﾀ0,5. 00 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 07080609020102ｨｪｨｪ0401 ｨｪｨ ｨｬｨｨ ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰｨ 05ｨｹｨｪ06 ｨ 0405ｨ 0106ｨｺｨ 04ｨ ｨｪｨ ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｹ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ07 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 01020706ｨｪｨｨ080609ｨ ｨｪｨｨ07 0608 010507 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ02ｨｦ ｨｺ08060502ｨｦ 0706 0609ｨｪ0609ｨｪ04ｨｬ 0706ｨｺｨ 04ｨ ｨｰ020507ｨｬ, ｨｰｨ ｨｺｨｨｨｬ ｨｺｨ ｨｺ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0602 01ｨ 090502ｨｪｨｨ02, 09ｨｰ020702ｨｪｨｹ 0706ｨｬｨｮｨｰｨｪ02ｨｪｨｨ07 0108ｨｮ09ｨｰｨ 05ｨｨｨｺｨ ｨｨ 09ｨｰ020702ｨｪｨｹ 090408ｨ 0302ｨｪｨｪ0609ｨｰｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0005ｨ 04ｨ ｨｪｨ 06070208ｨ 02ｨｨ06; ｨｰｨ ｨｺ0302 ｨｪｨｨ 09 0601ｨｪ06ｨｬ 0905ｨｮ ﾂｨ 02 ｨｪ02 ｨ 040506 090407090502ｨｪ06 0607ｨｨ09ｨ ｨｪｨｪ0401 0108ｨｮ00ｨｨｨｬｨｨ ｨ 09ｨｰ0608ｨ ｨｬｨｨ 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｨｨｰ0802ｨ 05ｨｹｨｪ06ｨｬ 0907060906ｨ 02 0909020102ｨｪｨｨ07 0609050603ｨｪ02ｨｪｨｨｨｦ (06ｨｰ090506ｨｦｨｺｨｨ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ, ｨｺ08060906ｨｨ0405ｨｨ07ｨｪｨｨ07 09 0702080201ｨｪ0606 ｨｺｨ ｨｬ0208ｨｮ ｨｨ 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ0602 ｨｰ020506, 05ｨｪ010600ｨｰｨ 05ｨｹｨｬｨｨｨｰｨ, 07090209010605ｨｪ010600ｨｰｨ 05ｨｹｨｬｨｨｨｰｨ ). 03080609060107 ｨ ｨｪｨ 05ｨｨ04 00ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨｨｺｨｨ 0608 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ06ｨｬ 0907060906ｨ 02 0909020102ｨｪｨｨ07 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 ｨｪｨ ｨｬ06010205ｨｨ ｨｺ08060502ｨｦ 06ｨｰｨｬ02ｨｰｨｨ05ｨｨ 09050201ｨｮ06ｨｴｨｨ02 060906ｨ 02ｨｪｨｪ0609ｨｰｨｨ (ｨｰｨ ｨ 05. 1, 08ｨｨ09. 2): 06ｨ ｨ 05ｨｨ02ｨ 1 02ｨｨｨｪｨ ｨｬｨｨｨｺｨ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 0708060202ｨｪｨｰｨｪ060006 06ｨｰｨｪ060302ｨｪｨｨ07 0005ｨ 04 09 0600ｨｰｨ 05ｨｹｨｬ0600ｨｨ070208ｨｰ02ｨｪ04ｨｨ02ｨｦ (> 25 ｨｬｨｬHg) 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ06ｨｬ 0907060906ｨ 02 0909020102ｨｪｨｨ07 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 09ｨｮｨ ｨｰ02ｨｪ06ｨｪ060904ｨｬ ｨｮ ｨｺ08060502ｨｦ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 0308ｨｨｨｬ02 ﾂｨ ｨｪｨｨ02. ｨC n 0908 ｨC 09080201ｨｪ0202 ｨｺ0605ｨｨ ﾂ0209ｨｰ0906 ｨｨ09090502010609ｨ ｨｪｨｪ0401 0005ｨ 04 09 0601ｨｨｨｪ 090806ｨｺ ｨｪｨ ｨ 05060102ｨｪｨｨ07. +J ﾀ ﾀ 06ｨ ｨ 05ｨｨ02ｨ 2 02ｨｨｨｪｨ ｨｬｨｨｨｺｨ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ060006 01ｨ 090502ｨｪｨｨ07 0706090502 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0907060906ｨ ｨ 0909020102ｨｪｨｨ07 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 09ｨｮｨ ｨｰ02ｨｪ06ｨｪ060904ｨｬ 0907060906ｨ 06ｨｬ ｨｮ ｨｺ08060502ｨｦ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 (ｨｬ0201ｨｨｨ ｨｪｨ, 25 ｨｨ 75-0702080202ｨｪｨｰｨｨ05ｨｹ) ﾀ +J +J ﾀ ﾀ ﾀ ﾀ ﾀ 0308ｨｨｨｬ02 ﾂｨ ｨｪｨｨ02. * ｨC 010609ｨｰ06090208ｨｪ0602 08ｨ 0405ｨｨ ﾂｨｨ02 ｨｬ020301ｨｮ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｬ 0106 0502 ﾂ02ｨｪｨｨ07 ｨｨ 09 01ｨｨｨｪｨ ｨｬｨｨｨｺ02 ｨｪｨ ｨ 05060102ｨｪｨｨ07 09 070802010205ｨ 01 0601ｨｪ06ｨｦ 0008ｨｮ070704. 06ｨ ｨ 05ｨｨ02ｨ 3 02ｨｨｨｪｨ ｨｬｨｨｨｺｨ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 09080201ｨｪ02ｨｦ 09ｨｰ020702ｨｪｨｨ 090408ｨ 0302ｨｪｨｪ0609ｨｰｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0706090502 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0907060906ｨ ｨ 0909020102ｨｪｨｨ07 ｨｰ08ｨｨｨ ｨｬ02ｨｨｨｪ060506ｨｪｨ ｨ 0202ｨｰ06ｨｪｨｨ01ｨ 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 09ｨｮｨ ｨｰ02ｨｪ06ｨｪ060904ｨｬ 0907060906ｨ 06ｨｬ ｨｮ ｨｺ08060502ｨｦ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 186
1302 04 06 01 06 01 08 09 05 01 04 03 05 06 08 06 05 06 1) 09 0802ｨｰｨｨｨｪ06010608ｨｨ06ｨｨ01ｨ 05ｨｹｨｪ06ｨｬ 09050602 ｨｨ0909050201ｨｮ02ｨｬ04ｨｦ 07080207ｨ 08ｨ ｨｰ 0607080201020507050907 ｨｪｨ ｨｨｨ 06050202 07080601060503ｨｨｨｰ0205ｨｹｨｪ06 (6 ｨｬ020907020209) 0706 0908ｨ 09ｨｪ02ｨｪｨｨ06 09 0108ｨｮ00ｨｨｨｬｨｨ ｨｨ0909050201ｨｮ02ｨｬ04ｨｬｨｨ ｨｰｨｺｨ ｨｪ07ｨｬｨｨ 09 090407090502ｨｪｨｪ06ｨｦ ｨｬｨｨｨｪｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｨ ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ02ｨｦ ｨC 157 ｨｪ00/ｨｬ05 ｨｨ 17287 ｨｪ00/ｨｬ05; 2) 09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ06ｨｬ ｨｰ020502 ｨｨ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ06ｨｦ 03ｨｨ01ｨｺ0609ｨｰｨｨ 0608 0607080201020507050907 3 ｨｬ02090702ｨ 09 090407090502ｨｪｨｪ06ｨｦ ｨｬｨｨｨｪｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ (18 ｨｪ00/ｨｬ05 ｨｨ 5 ｨｪ00/ｨｬ05) ｨｨ ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ02ｨｦ ｨC 1436 ｨｪ00/ｨｬ05 ｨｨ 1339 ｨｪ00/ｨｬ05 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06; 3) 09 0705ｨ 04ｨｬ02 ｨｺ080609ｨｨ ｨｨ0909050201ｨｮ02ｨｬ04ｨｦ 07080207ｨ 08ｨ ｨｰ 0607080201020507050907 ｨｪｨ ｨｨｨｬ02ｨｪ0202 07080601060503ｨｨｨｰ0205ｨｹｨｪ06 (7 01ｨｪ02ｨｦ) 09 090407090502ｨｪｨｪ06ｨｦ ｨｬｨｨｨｪｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｨ ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪ06ｨｦ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨ02ｨｦ 1 ｨｪ00/ｨｬ05 ｨｨ 2,7 ﾀ0,4 ｨｪ00/ｨｬ05; 4) 0706010603ｨ 07 000608ｨｬｨ ｨｺ08ｨｨ0906ｨｦ 01ｨｨｨｪｨ ｨｬｨｨｨｺｨｨ ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨ 07080207ｨ 08ｨ ｨｰｨ 0906 09090201 ｨｨ0909050201ｨｮ02ｨｬ0401 ｨｰｨｺｨ ｨｪ0701 0005ｨ 04ｨ : ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪｨ 07 ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨ ﾂ02080204 3 ﾂｨ 09ｨ 0706090502 ｨｨｨｪｨｲ02ｨｺ02ｨｨｨｨ, ｨｪｨ 09050201ｨｮ06ｨｴｨｨｨｦ 0102ｨｪｨｹ ｨC 09ｨｪｨｨ0302ｨｪｨｨ02 ｨｺ06ｨｪ0202ｨｪｨｰ08ｨ 02ｨｨｨｨ 0608 09 070609050201ｨｮ06ｨｴｨｨｨｬ 070601ｨｲ02ｨｬ06ｨｬ ｨｪｨ 3 0102ｨｪｨｹ ｨｨ 070609ｨｰ0608ｨｪ04ｨｬ 09ｨｪｨｨ0302ｨｪｨｨ02ｨｬ ｨｪｨ 7 0102ｨｪｨｹ (09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ06ｨｬ ｨｰ020502 ｨｨ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ06ｨｦ 03ｨｨ01ｨｺ0609ｨｰｨｨ) ｨｨ05ｨｨ 14 0102ｨｪｨｹ (09 0802ｨｰｨｨｨｪ06010608ｨｨ06ｨｨ01ｨ 05ｨｹｨｪ06ｨｬ 09050602). 02ｨ ｨｴｨ 07 ｨｰ06050208ｨ ｨｪｨｰｨｪ0609ｨｰｨｹ 09ｨｺ05020804 ｨｨ 06ｨｺ08ｨｮ03ｨ 06ｨｴｨｨ01 0202 ｨｰｨｺｨ ｨｪ02ｨｦ ｨｺ ｨｨｨｪ06080601ｨｪ04ｨｬ ｨｰ0205ｨ ｨｬ 0106ｨｺｨ 04ｨ ｨｪｨ 09 ｨｰ02 ﾂ02ｨｪｨｨｨｨ 01060500ｨｨ01 0502ｨｰ 0708ｨｨｨｬ02ｨｪ02ｨｪｨｨ07 09ｨｺ050208ｨ 05ｨｹｨｪ0401 0300ｨｮｨｰ0609 0708ｨｨ 06ｨｰ090506ｨｦｨｺ02 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ, ﾂｨｰ06 010205ｨ 02ｨｰ 0202 07060101060107ｨｴ02ｨｦ 010507 01020706ｨｪｨｨ080609ｨ ｨｪｨｨ07 07080207ｨ 08ｨ ｨｰ0609. 02 ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ060006 0909020102ｨｪｨｨ07 ｨｨｨｬ0705ｨ ｨｪｨｰｨ ｨｰ0609 09 6,4 ｨｬ00 0608 010507 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ02ｨｦ 09 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰ02 ｨｪｨ ｨｺ0806050701 0909ｨｨ0102ｨｰ0205ｨｹ09ｨｰ09ｨｮ06ｨｰ ｨｨ 080204ｨｮ05ｨｹｨｰｨ ｨｰ04 ｨｨ09090502010609ｨ ｨｪｨｨｨｦ Yu-Mi Kim ｨｨ 0906ｨ 09ｨｰ. [1], ｨｺ06ｨｰ06080402 09040709ｨｨ05ｨｨ ｨｨ01 ｨ ｨｨ06050600ｨｨ ﾂ0209ｨｺｨｮ06 090609ｨｬ0209ｨｰｨｨｨｬ0609ｨｰｨｹ ｨｨ 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ02 ｨｰ06ｨｺ09ｨｨ ﾂｨｪ0609ｨｰｨｨ. 0201ｨｪｨ ｨｺ06 09 ｨｮｨｺｨ 04ｨ ｨｪｨｪ06ｨｬ ｨｨ09090502010609ｨ ｨｪｨｨｨｨ 070208ｨｨ0601 ｨｪｨ ｨ 05060102ｨｪｨｨ07 090609ｨｰｨ 09050705 3 ｨｬ02090702ｨ, ﾂｨｰ06 ｨｪ02 01ｨ 09ｨ 0506 090604ｨｬ0603ｨｪ0609ｨｰｨｨ 09040709ｨｨｨｰｨｹ 0607ｨｨ09ｨ ｨｪｨｪ0402 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｨｨｰ0802ｨ 05ｨｹｨｪ06ｨｬ 0909020102ｨｪｨｨｨｨ 07060401ｨｪｨｨ02 0609050603ｨｪ02ｨｪｨｨ07 (0708060008020909ｨｨ080609ｨ ｨｪｨｨ02 ｨｺｨ ｨｰｨ 08ｨ ｨｺｨｰ04). 030605ｨｮ ﾂ02ｨｪｨｪ0402 ｨｪｨ ｨｬｨｨ 01ｨ ｨｪｨｪ0402 06 00ｨ 08ｨｬｨ ｨｺ06ｨｺｨｨｨｪ02ｨｰｨｨｨｺ02 0608 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ06ｨｬ 0909020102ｨｪｨｨｨｨ 09060005ｨ 09ｨｮ06ｨｰ0907 09 080204ｨｮ05ｨｹｨｰｨ ｨｰｨ ｨｬｨｨ Yu-Mi Kim ｨｨ 0906ｨ 09ｨｰ. [1], ｨｺ06ｨｰ06080402 ｨｰｨ ｨｺ0302 06ｨ ｨｪｨ 08ｨｮ03ｨｨ05ｨｨ ｨｨ0909050201ｨｮ02ｨｬ04ｨｦ 07080207ｨ 08ｨ ｨｰ 09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ06ｨｬ ｨｰ020502 09 060708020102050702ｨｬ06ｨｦ 01060402 0706090502 0909020102ｨｪｨｨ07 ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ0401 ｨｨｨｬ0705ｨ ｨｪｨｰｨ ｨｰ0609 09 6,4 ｨｬ00 0608 ｨｪｨ 070806ｨｰ070302ｨｪｨｨｨｨ 3 ｨｬ020907020209. 0201ｨｪｨ ｨｺ06 09050201ｨｮ02ｨｰ 06ｨｰｨｬ02ｨｰｨｨｨｰｨｹ 08ｨ 0405ｨｨ ﾂｨｨ07 09 080204ｨｮ05ｨｹｨｰｨ ｨｰｨ 01 ｨｨ09090502010609ｨ ｨｪｨｨ07 0108ｨｮ00ｨｨ01 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ02ｨｦ. 06ｨ ｨｺ, Yu-Mi Kim ｨｨ 0906ｨ 09ｨｰ. 09 0802ｨｰｨｨｨｪ06010608ｨｨ06ｨｨ010202 060708020102050705ｨｨ 0608 0106 2 ｨｬ020907020209, ｨ 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ06ｨｦ 03ｨｨ01ｨｺ0609ｨｰｨｨ 0106 1 ｨｬ02090702ｨ (09 ｨｪｨ 0302ｨｬ ｨｨ09090502010609ｨ ｨｪｨｨｨｨ ｨC 6 ｨｨ 3 ｨｬ02090702ｨ 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06). 04ｨ 0405ｨｨ ﾂｨｨ02 09 070605ｨｮ ﾂ02ｨｪｨｪ0401 080204ｨｮ05ｨｹｨｰｨ ｨｰｨ 01 ｨｬ0603ｨｪ06 06ｨ ｨｲ0709ｨｪｨｨｨｰｨｹ 08ｨ 04ｨｪ06ｨｦ 01060406ｨｦ (40 ｨｬ00 ｨC 0708ｨｨ ｨｪｨ 0302ｨｬ 0907060906ｨ 02, 6,4 ｨｬ00 ｨC 0708ｨｨ 0607ｨｨ09ｨ ｨｪｨｪ06ｨｬ 08ｨ ｨｪ0202), ｨ ｨｰｨ ｨｺ0302 08ｨ 04ｨｪ06ｨｦ ｨｰ0201ｨｪｨｨｨｺ06ｨｦ 0909020102ｨｪｨｨ07 0608 (09 09ｨｨ0102 ｨｺ08ｨｨ09ｨｰｨ 05050609 ｨC 0708ｨｨ ｨｪｨ 0302ｨｬ 0907060906ｨ 02, 09 09ｨｨ0102 ｨｨｨｬ0705ｨ ｨｪｨｰｨ ｨｰｨ ｨC 0708ｨｨ 08ｨ ｨｪ0202 0607ｨｨ09ｨ ｨｪｨｪ06ｨｬ). 080806ｨｬ02 ｨｰ060006, 07080601060503ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｹ 05ｨｺ09070208ｨｨｨｬ02ｨｪｨｰｨ 05ｨｹｨｪ060006 ｨｨ09090502010609ｨ ｨｪｨｨ07 Yu-Mi Kim ｨｨ 0906ｨ 09ｨｰ. (3 ｨｬ02090702ｨ ) 06ｨｰ05ｨｨ ﾂｨ 05ｨ 09ｨｹ 06ｨｰ ｨｪｨ 03020006 (7 ｨｬ020907020209). 000400020204 01ｨ 0609ｨｪ0609ｨ ｨｪｨｨｨｨ 07080609020102ｨｪｨｪ0401 ｨｨ09090502010609ｨ ｨｪｨｨｨｦ 0106ｨｺｨ 04ｨ ｨｪｨ 05000002ｨｺｨｰｨｨ09ｨｪ0609ｨｰｨｹ ｨｨ ｨ 02040607ｨ 09ｨｪ0609ｨｰｨｹ 010507 09ｨｪｨｮｨｰ08ｨｨ0005ｨ 04ｨｪ0401 ｨｰｨｺｨ ｨｪ02ｨｦ 40 ｨｬ00 ｨｺ08ｨｨ09ｨｰｨ 05050609 0608 0708ｨｨ ｨｨｨｪｨｰ08ｨ 09ｨｺ050208ｨ 05ｨｹｨｪ06ｨｬ 01020706ｨｪｨｨ080609ｨ ｨｪｨｨｨｨ. 09060603040806070408 1. A novel design of one-side coated biodegradable intrascleral implant for the sustained release of triamcinolone acetonide / Y. M. Kim, J. O. Lim, H. K. Kim et al. // European Journal of Pharmaceutics and Biopharmaceutics. ｨC 2008. ｨC Vol. 70. ｨC 04. 179-186. 2. A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide / M. R. Robinson, S. S. Lee, H. Kim et al. // Experimental Eye Research. ｨC 2006. ｨC Vol. 82 (3). ｨC 04. 479-487. 3. Assessment of Subconjunctival and Intrascleral Drug Delivery to the Posterior Segment Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging. Stephanie / H. Kim, C. J. Galbn, R. J. Lutz et al. // Investigative Ophthalmology and Visual Science. ｨC 2007. ｨC Vol. 48. ｨC 04. 808-814. 4. Characterization of a novel intraocular drugdelivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir / L. Cheng, K. Y. Hostetler, J. Lee et al. // Investigative Ophthalmology and Visual Science. ｨC 2004. ｨC Vol. 45. ｨC 04. 4138-4144. 5. Characterisation of systemic and ocular drug level of triamcinolone acetonide following a single sub-tenon injection / K. Nan, S. Sun, Y. Li et al. // British Journal of Ophthalmology. ｨC 2010. ｨC Vol. 94. ｨC 04. 654-658. 6. Comparison of different techniques for purification of triamcinolone acetonide suspension for intravitreal use / J. Garcia-Arumi, A. Boixadera, J. Giralt et al. // British Journal of Ophthalmology. ｨC 2005. ｨC Vol. 89. ｨC 04. 1112-1114. 7. Controlled drug release from an ocular implant: an evaluation using dynamic three-dimensional magnetic resonance imaging / H. Kim, M. R. Robinson, M. J. Lizak et al. // Investigative Ophthalmology and Visual Science. ｨC 2004. ｨC Vol. 45. ｨC 04. 2722-2731. 8. Delivery from episcleral exoplants / R. A. Pontes de Carvalho, M. L. Krausse, A. L. Murphree et al.// Investigative Ophthalmology and Visual Science. ｨC 2006. ｨC Vol. 47. ｨC 04. 4532-4539. 9. Ghosn M. G. Nondestructive uantification of Analyte Diffusion in Cornea and Sclera Using Optical Coherence Tomography / M. G. Ghosn, V. V. Tuchin, K. V. Larin // Investigative Ophthalmology and Visual Science. ｨC 2007. ｨC Vol.48. ｨC P. 2726-2733. 10. Intravitreal Injection Versus Sub-Tenon's Infusion of Triamcinolone Acetonide for Refractory Diabetic Macular Edema: A Randomized Clinical / T. M. A. Bonini-Filho, R. Jorge, J. C. Barbosa et al. // Investigative Ophthalmology and Visual Science. ｨC 2005. ｨC Vol. 46. ｨC 04. 3845-3849. 187
132011, ｨｰ06ｨｬ 14, 014 ﾂ.2 (56) 0608000406 ﾁ0305080607 000302060802-09060209020106 ﾁ0305080607 00030506010608 11. Intravitreal vs. subtenon triamcinolone acetonide for the treatment of diabetic cystoid macular edema / M. Cellini, A. Pazzaglia, E. Zamparini et al. // BMC Ophthalmology. ｨC 2008. ｨC Vol. 8. ｨC 04. 5. 12. Pharmacokinetics of Intraocular Drug Delivery by Periocular Injections Using Ocular Fluorophotometry / D. Ghate, W. Brooks, B. E. McCarey et al. // Investigative Ophthalmology and Visual Science. ｨC 2007. ｨC Vol. 48. ｨC 04. 2230-2237. 13. Sallam A. Intraocular delivery of anti-infective drugs-bacterial, viral, fungal and parasitic / A. Sallam, S. Jayakumar, S. Lightman // Recent Patents on Anti-Infective Drug Discovery. ｨC 2008. ｨC Vol. 3 (1). ｨC 04. 53-63. 14. Short B. G. Safety evaluation of ocular drug delivery formulations: techniques and practical considerations / B. G. Short // Toxicologic Pathology. ｨC 2008. ｨC Vol. 36 (1). ｨC 04. 49-62. 188
1302 04 06 01 06 01 08 09 05 01 04 03 05 06 08 06 05 06 070208 617.76-002.1:617.731 08 0806050502ｨｺｨｰｨｨ09 ｨ 09ｨｰ06080609, 2011. 0205020903010102050606 030204080403010608 0504060603090501020102 0103040008 07 030800060301060200 05 02050604040006 000205030809060603090501040006 05080902090300080106080006 020409060604 03.08. 0902040102ｨｰｨｺ06, 02.08. 05ｨｮｨ ｨｺ0609ｨ, 02.00. 05ｨ 09060506ｨｺｨ, 00.01. 08ｨｮ02ｨｨｨｪ, 09.07. 090608ｨｨ090609ｨ 09ｨ 08ｨｹｨｺ060909ｨｺｨｨｨｦ ｨｪｨ 02ｨｨ06ｨｪｨ 05ｨｹｨｪ04ｨｦ ｨｬ0201ｨｨ02ｨｨｨｪ09ｨｺｨｨｨｦ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ, ｨｺｨ 00020108ｨ 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨｨｨ, ｨｪｨ ｨｮ ﾂｨｪ04ｨｦ 08ｨｮｨｺ06090601ｨｨｨｰ0205ｨｹ 01.ｨｬ0201.ｨｪ., 07080600. 03. 08. 0902040102ｨｰｨｺ06, 00. 09ｨ 08ｨｹｨｺ0609 PECULIARITIES OF THE OPTIC NERVE LESION AMONG PATIENTS WITH ACUTE INFLAMMATORY DISEASES OF THE ORBIT P.A. Bezditko, D.A. Zubkova, O.V. Zavoloka, V.N. Koutsyn, L.U. Borisova SUMMARY Peculiarities of the optic nerve lesion among patients with acute inflammatory diseases of the orbit were analyzed. There have been carried out computed tomography, helical computed tomography, and magnetic resonance tomography with further analysis of the scanning images with the help of the software 00eFilm Lite 1998-200303, phosphene diagnostics besides ordinary ophthalmological examinations. Optic nerve lesion among mentioned above patients was observed in 16,7 % of cases. This abnormality was characterized by intrabulbar and orbital parts of the optic nerve affection. The damage level was conditioned by the character of the inflammatory process in the orbit and the total volume of the orbital soft tissues. Damage rate of the visual function was conditioned by the degree of diameter extension of the orbital part of the optic nerve and superior ophthalmic vein as well as the change of their diameter ratio. 0205020909060002050605 0704080403010108 0502040200020102 0103040008 07 030800050901060500 05 0102050604060006 05080308090501060006 0508090002040700080101080006 020409050606 03.08. 0902040106ｨｰｨｺ06, 02.02. 05ｨｮｨ ｨｺ0609ｨ, 02.00. 05ｨ 09060506ｨｺｨ, 00.00. 08ｨｮ02ｨｨｨｪ, 09.07. 090608ｨｨ090609ｨ 040305070003 030806ｨ ｨｪｨ 0506040609ｨ ｨｪ06 060906ｨ 05ｨｨ090609ｨｰ06 ｨｮ08ｨ 0302ｨｪｨｪ07 0406080609060006 ｨｪ020809ｨ ｨｮ 84 07ｨ 020602ｨｪｨｰ0609 04 000609ｨｰ08ｨｨｨｬｨｨ 04ｨ 07ｨ 05ｨｹｨｪｨｨｨｬｨｨ 04ｨ 010906080609ｨ ｨｪｨｪ07ｨｬｨｨ 0608ｨ 06ｨｰｨｨ. 080806ｨｬ 09ｨｰｨ ｨｪ01ｨ 08ｨｰｨｪ060006 0600ｨｰｨ 05ｨｹｨｬ0605060006 ﾂｨｪ060006 06ｨ 09ｨｰ020302ｨｪｨｪ07 07080609020102ｨｪ06 ｨｺ06ｨｬ07`06ｨｰ0208ｨｪｨ, 09070608ｨ 05ｨｹｨｪｨ ｨｺ06ｨｬ07`06ｨｰ0208ｨｪｨ, ｨ ｨｰｨ ｨｺ0603 ｨｬｨ 00ｨｪ06ｨｰｨｪ06-08020406ｨｪｨ ｨｪ09ｨｪｨ ｨｰ06ｨｬ060008ｨ 000607 04 ｨｪｨ 09ｨｰｨｮ07ｨｪｨｨｨｬ ｨ ｨｪｨ 05060406ｨｬ 09ｨｺｨ ｨｪ060008ｨ ｨｬ 04ｨ 01060706ｨｬ06000606 0708060008ｨ ｨｬｨｪ060006 04ｨ ｨ 02040702 ﾂ02ｨｪｨｪ07 00eFilm Lite 1998-200303, 0006090002ｨｪ-0106ｨ 00ｨｪ0609ｨｰｨｨｨｺｨ. 0708ｨ 0302ｨｪｨｪ07 0406080609060006 ｨｪ020809ｨ 09070609ｨｰ02080600ｨ 05060907 ｨｮ 16,7 % 09ｨｨ07ｨ 01ｨｺ0609 000609ｨｰ08ｨｨ01 04ｨ 07ｨ 05ｨｹｨｪｨｨ01 04ｨ 010906080609ｨ ｨｪｨｹ 0608ｨ 06ｨｰｨｨ. 020507 ｨｰｨ ｨｺｨｨ01 07ｨ 020602ｨｪｨｰ0609 ｨ ｨｮ05ｨｨ 01ｨ 08ｨ ｨｺｨｰ0208ｨｪ06 0604ｨｪｨ ｨｺｨｨ ｨｮ08ｨ 0302ｨｪｨｪ07 06ｨｪｨｰ08ｨ ｨ ｨｮ05ｨｹｨ ｨ 08ｨｪ0607 ｨｰｨ 0608ｨ 06ｨｰｨ 05ｨｹｨｪ0607 ﾂｨ 09ｨｰｨｨｨｪｨｨ 0406080609060006 ｨｪ020809ｨ. 05ｨｰｨｮ0706ｨｪｨｹ ｨｮ08ｨ 0302ｨｪｨｪ07 0406080609060006 ｨｪ020809ｨ 04ｨ 050203ｨ 05ｨ 090601 01ｨ 08ｨ ｨｺｨｰ0208ｨｮ 04ｨ 07ｨ 05ｨｹｨｪ060006 070806020209ｨｮ 09 06 ﾂｨｪ06ｨｦ 07ｨｬ0206 06 09ｨｮｨｬｨ 08ｨｪ060006 06ｨ '02ｨｬｨｮ ｨｬ'07ｨｺｨｨ01 ｨｰｨｺｨ ｨｪｨｨｨｪ 0608ｨ 06ｨｰｨｨ. 00ｨｨ08ｨ 0302ｨｪ0609ｨｰｨｹ 070608ｨｮ0302ｨｪｨｪ07 0406080609ｨｨ01 00ｨｮｨｪｨｺ0206ｨｦ 04ｨ 050203ｨ 05ｨ 090601 09ｨｰｨｮ0702ｨｪ07 04ｨ 0605ｨｹ0302ｨｪｨｪ07 0106ｨ ｨｬ02ｨｰ08ｨ 0608ｨ 06ｨｰｨ 05ｨｹｨｪ0607 ﾂｨ 09ｨｰｨｨｨｪｨｨ 0406080609060006 ｨｪ020809ｨ ｨｰｨ 09020801ｨｪｨｹ0607 06 ﾂｨｪ0607 0902ｨｪｨｨ, ｨ ｨｰｨ ｨｺ0603 04ｨｬ06ｨｪ02ｨｪｨｪ07 09070609090601ｨｪ060302ｨｪｨｪ07 0701 0106ｨ ｨｬ02ｨｰ080609. 080506 ﾂ02090402 09050609ｨ : 0609ｨｰ080402 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ0402 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 0608ｨ ｨｨｨｰ04, 070608ｨ 0302ｨｪｨｨ02 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ 0209ｨｰ080402 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ0402 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 0608ｨ ｨｨｨｰ04 0709050706ｨｰ0907 ｨｺｨ ｨｰ02000608ｨｨ02ｨｦ ｨｰ070302050401 090609ｨｰ0607ｨｪｨｨｨｦ, ｨｺ06ｨｰ06080402 ｨｬ0600ｨｮｨｰ 0708ｨｨ090209ｨｰｨｨ ｨｪ02 ｨｰ0605ｨｹｨｺ06 ｨｺ ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ06 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ, ｨｪ06 ｨｨ ｨｺ 09ｨｬ0208ｨｰｨｨ ｨ 0605ｨｹｨｪ060006 [2]. 08 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬ 01ｨ ｨｪｨｪ06ｨｦ 0008ｨｮ070704 06ｨｰｨｪ060907ｨｰ: 0609ｨｰ0206070208ｨｨ0609ｨｰｨｨｨｰ, 09ｨｮｨ 070208ｨｨ0609ｨｰｨ 05ｨｹｨｪ04ｨｦ ｨｨ 0802ｨｰ0806ｨ ｨｮ05ｨｹｨ ｨ 08ｨｪ04ｨｦ ｨ ｨ 0902020909, 07080609ｨｰ06ｨｦ 06ｨｰ00ｨｺ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ｨｺ0502ｨｰ ﾂｨ ｨｰｨｺｨｨ ｨｨ 00050200ｨｬ06ｨｪｨｮ 0608ｨ ｨｨｨｰ04, ｨｺ06ｨｰ06080402 ｨｪ02080201ｨｺ06 0709050706ｨｰ0907 09ｨｰｨ 01ｨｨ07ｨｬｨｨ 0601ｨｪ060006 07ｨ ｨｰ06050600ｨｨ ﾂ0209ｨｺ060006 07080602020909ｨ [1-5, 8]. 08 ｨｰ0703020504ｨｬ 07060905020109ｨｰ09ｨｨ07ｨｬ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ0401 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ0401 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ 06ｨｰｨｪ060907ｨｰ0907 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ. 0306 01ｨ ｨｪｨｪ04ｨｬ 09ｨｨ0801-01ｨｨ0803000205ｨｹ01ｨ [3] ｨｮ 16% 07ｨ 02ｨｨ02ｨｪｨｰ0609 08ｨ 0409ｨｨ09ｨ 02ｨｰ0907 0105ｨｨｨｰ0205ｨｹｨｪ04ｨｦ ｨ ｨｬｨ 09080604, 09 12% ｨC 07080201060107ｨｴｨｨ02 ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 040802ｨｪｨｨ07. 0308ｨｨ ﾂｨｨｨｪ06ｨｦ 09ｨｪｨｨ0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ 0709050706ｨｰ0907 070608ｨ 0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ [7], 06ｨｰ02ｨｺ 070208ｨｨｨｪ020908ｨ 05ｨｹｨｪ0401 06ｨ 060506 ﾂ02ｨｺ, ｨｰ0806ｨｬｨ 06000502ｨ ｨｨｨｰ 0902ｨｪ ｨｨ ｨｰ0806ｨｬｨ 0604 ｨ 08ｨｰ0208ｨｨｨｦ [9, 10] 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ, 0200 06ｨｰ090506ｨｦｨｺｨ, 07ｨ ｨｪ0600ｨｰｨ 05ｨｹｨｬｨｨｨｰ ｨｨ 01ｨ 0302 0005ｨ ｨｮｨｺ06ｨｬｨ [1-7]. 0306 ｨｬｨｪ02ｨｪｨｨ06 08. 08. 09080609ｨｺｨｨｨｪ06ｨｦ [2], 0708ｨｨ ﾂｨｨｨｪ06ｨｦ 0905020706ｨｰ04 ｨｬ060302ｨｰ ｨ 04ｨｰｨｹ 0609ｨｰ0804ｨｦ ｨｪ020908ｨｨｨｰ 09 080204ｨｮ05ｨｹｨｰｨ ｨｰ02 05ｨｬｨ 0605ｨ ｨｨ05ｨｨ ｨｰ0806ｨｬｨ 0604ｨ 090609ｨｮ010609 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ, 0902ｨｰ- ﾂｨ ｨｰｨｺｨｨ ｨｨ05ｨｨ 010608ｨｨ06ｨｨ0102ｨｨ. 080806ｨｬ02 ｨｰ060006, 09 ｨｪｨ 08ｨｮ0302ｨｪｨｨｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ ｨｨ0008ｨ 02ｨｰ 080605ｨｹ 080204ｨｺ06 ｨｪｨ 08ｨ 09ｨｰｨ 06ｨｴｨｨｨｦ 05ｨｺ040600ｨｰｨ 05ｨｹｨｬ, 0708ｨｨ09060107ｨｴｨｨｨｦ ｨｺ ｨ 0409ｨｰ0806ｨｬｨｮ ｨｪｨ ｨｰ070302ｨｪｨｨ06 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ, ｨｺ06ｨｪｨｨ ﾂ0209ｨｺ06ｨｬｨｮ 0904ｨｰ0700ｨｨ09ｨ ｨｪｨｨ06 04ｨ 01ｨｪ020006 0706050609ｨ 0005ｨ 04ｨ, ﾂｨｰ06 0708ｨｨ090601ｨｨｨｰ ｨｺ 07ｨ 0102ｨｪｨｨ06 01ｨ 090502ｨｪｨｨ07 09 ｨ 08ｨｰ0208ｨｨ0701, ｨｨ ｨｪｨ 08ｨ 09ｨｰｨ ｨｪｨｨ06 01ｨ 090502ｨｪｨｨ07 09 0902ｨｪｨ 01, ｨｨ, ｨｺｨ ｨｺ 0905020109ｨｰ09ｨｨ02, 08ｨ 0409ｨｨｨｰｨｨ06 ｨｨ0302ｨｬｨｨｨｨ ｨｪｨ 0005ｨ 04ｨｪ06ｨｬ 01ｨｪ02. 000205ｨｹ06 01ｨ ｨｪｨｪ060006 ｨｨ09090502010609ｨ ｨｪｨｨ07 07090507050609ｨｹ ｨｮｨｰ06 ﾂｨｪ02ｨｪｨｨ02 060906ｨ 02ｨｪｨｪ0609ｨｰ02ｨｦ 070608ｨ 0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ ｨｮ 189
132011, ｨｰ06ｨｬ 14, 014 ﾂ.2 (56) 0608000406 ﾁ0305080607 000302060802-09060209020106 ﾁ0305080607 00030506010608 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 0609ｨｰ0804ｨｬｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0608ｨ ｨｨｨｰ04. 000806030406080904 06 000306020204 04ｨ ｨ 06ｨｰｨ 0904070605ｨｪ02ｨｪｨ ｨｪｨ 0609ｨｪ0609ｨ ｨｪｨｨｨｨ 0802ｨｰ0806090702ｨｺｨｰｨｨ09ｨｪ060006 ｨ ｨｪｨ 05ｨｨ04ｨ ｨｨ 0906ｨ 09ｨｰ0902ｨｪｨｪ0401 ｨｪｨ ｨ 05060102ｨｪｨｨｨｦ 84 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 0609ｨｰ0804ｨｬｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0608ｨ ｨｨｨｰ04 09 09060408ｨ 09ｨｰ02 06ｨｰ 14 0106 79 0502ｨｰ. 05080201ｨｨ ｨｪｨｨ01 ｨ 0405ｨｨ 61 (72,6 %) ｨｬｨｮ03 ﾂｨｨｨｪｨ ｨｨ 23 (27,4 %) 0302ｨｪｨｴｨｨｨｪ04. 00 04ｨ 09ｨｨ09ｨｨｨｬ0609ｨｰｨｨ 06ｨｰ 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ 0708ｨｨ 070609ｨｰｨｮ070502ｨｪｨｨｨｨ, ｨ 0605ｨｹｨｪ0402 ｨ 0405ｨｨ 08ｨ 0401020502ｨｪ04 ｨｪｨ 4 0008ｨｮ070704. 03020809ｨｮ06 0008ｨｮ0707ｨｮ 090609ｨｰｨ 09ｨｨ05ｨｨ 4 ﾂ0205060902ｨｺｨ (4,76 %) 09 ｨ ｨｬｨ 0908060406ｨｬ. 0006 2 0008ｨｮ070702 ｨ 040506 5 07ｨ 02ｨｨ02ｨｪｨｰ0609 (5,95 %) 09 07080201ｨｬ02ｨｰｨｪ04ｨｬ 040802ｨｪｨｨ02ｨｬ. 060802ｨｰｨｹ06 0008ｨｮ0707ｨｮ 090609ｨｰｨ 09ｨｨ05ｨｨ 5 ｨ 0605ｨｹｨｪ0401 (5,95 %), 0609ｨｰ0806ｨｰｨ 040802ｨｪｨｨ07 ｨｺ06ｨｰ06080401 09 09080201ｨｪ02ｨｬ ｨ 0405ｨ 0,68 ﾀ2,12. 07 0609ｨｰｨ 05ｨｹｨｪ0401 70 07ｨ 02ｨｨ02ｨｪｨｰ0609 (71,42 %) 0609ｨｰ0806ｨｰｨ 040802ｨｪｨｨ07 090609ｨｰｨ 09ｨｨ05ｨ 0,97 ﾀ0,02 (0609ｨｪ0609ｨｪｨ 07 0008ｨｮ0707ｨ ). 080806ｨｬ02 09ｨｰｨ ｨｪ01ｨ 08ｨｰｨｪ060006 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨ ﾂ0209ｨｺ060006 06ｨ 090502010609ｨ ｨｪｨｨ07, 07ｨ 02ｨｨ02ｨｪｨｰｨ ｨｬ 070806090601ｨｨ05ｨｨ ｨｺ06ｨｬ07ｨｹ06ｨｰ0208ｨｪｨｮ06 ｨｰ06ｨｬ060008ｨ 00ｨｨ06, 0907ｨｨ08ｨ 05ｨｹｨｪ06-ｨｺ06ｨｬ07ｨｹ06ｨｰ0208ｨｪｨｮ06 ｨｰ06ｨｬ060008ｨ 00ｨｨ06, ｨ ｨｰｨ ｨｺ0302 ｨｬｨ 00ｨｪｨｨｨｰｨｪ06-08020406ｨｪｨ ｨｪ09ｨｪｨｮ06 ｨｰ06ｨｬ060008ｨ 00ｨｨ06 09 070609050201ｨｮ06ｨｴｨｨｨｬ ｨ ｨｪｨ 05ｨｨ0406ｨｬ 09ｨｺｨ ｨｪ060008ｨ ｨｬｨｬ 09 0706ｨｬ06ｨｴｨｹ06 0708060008ｨ ｨｬｨｬｨｪ060006 06ｨ 02090702 ﾂ02ｨｪｨｨ07 00eFilm Lite 1998-200303, ｨ ｨｰｨ ｨｺ0302 0006090002ｨｪ-01ｨｨｨ 00ｨｪ0609ｨｰｨｨｨｺｨｮ. 05ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨ 07 06ｨ 08ｨ ｨ 06ｨｰｨｺｨ ｨｨｨｪ000608ｨｬｨ 02ｨｨｨｨ 0609ｨｮｨｴ0209ｨｰ09050705ｨ 09ｨｹ 09 ｨｨ09070605ｨｹ040609ｨ ｨｪｨｨ02ｨｬ ｨｬ02ｨｰ06010609 09ｨ 08ｨｨｨ 02ｨｨ06ｨｪｨｪ06ｨｦ 09ｨｰｨ ｨｰｨｨ09ｨｰｨｨｨｺｨｨ 09 0706ｨｬ06ｨｴｨｹ06 ｨｺ06ｨｬ07ｨｹ06ｨｰ0208ｨｪ06ｨｦ 0708060008ｨ ｨｬｨｬ04 00Excel 200703. 04030507090506080604 06 0609 02090507040203010603 07 09090201 ｨ 0605ｨｹｨｪ0401 09 ｨ ｨｬｨ 0908060406ｨｬ ｨ 0405ｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪｨ 00050200ｨｬ06ｨｪｨ 0608ｨ ｨｨｨｰ04. 05ｨｬ02ｨｴ02ｨｪｨｨ02 0005ｨ 04ｨｪ060006 07ｨ 0506ｨｺｨ ｨｺ0702080201ｨｨ 09 09080201ｨｪ02ｨｬ 090609ｨｰｨ 09ｨｨ0506 28,47 ﾀ0,72 ｨｬｨｬ, ﾂｨｰ06 090607080609060301ｨ 050609ｨｹ 05ｨ 000600ｨｰｨ 05ｨｹｨｬ06ｨｬ ｨｨ ｨｨｨｪ00ｨｨ05ｨｹｨｰ08ｨ ｨｰ06ｨｬ 0806000609ｨｨ0204. 01ｨ ｨ 050601ｨ 050907 ｨｬｨｨ0108ｨｨｨ 04 (5,91 ﾀ0,14 ｨｬｨｬ), 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ02 070807ｨｬ06ｨｦ ｨｨ 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨ02ｨｦ 0408ｨ ﾂｨｺｨ ｨｪｨ 090902ｨｰ, ｨ ｨｰｨ ｨｺ0302 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0408ｨ ﾂｨｺｨ ｨｪｨ ｨ ｨｺｨｺ06ｨｬ0601ｨ 02ｨｨ06 ｨｨ ｨｺ06ｨｪ0902080002ｨｪ02ｨｨ06. 0308ｨｨ 0600ｨｰｨ 05ｨｹｨｬ0609ｨｺ0607ｨｨｨｨ 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪ06 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 020501, 020006 00ｨｨ07020802ｨｬｨｨ07, 08ｨ 04ｨｬ04ｨｰ0609ｨｰｨｹ 0008ｨ ｨｪｨｨ02 0909020006 ｨｺ08ｨ 07, ｨ ｨｰｨ ｨｺ0302 070806ｨｬｨｨｨｪ02ｨｪ02ｨｨ07 09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ0602 ｨｰ020506 09 09080201ｨｪ02ｨｬ ｨｪｨ 3,5 ｨｬｨｬ, ｨｺ0806ｨｬ02 ｨｰ060006 1-2 03ｨｰ08ｨｨ0106090402 ｨｨ 4-5 ｨｰ06 ﾂ02 ﾂｨｪ0402 ｨｺ08060906ｨｨ0405ｨｨ07ｨｪｨｨ07 0706 ｨｺ08ｨ 06 020501, ｨｨ 09 070208ｨｨ07ｨ 07ｨｨ05050708ｨｪ06ｨｦ 0406ｨｪ02, ｨｮｨｬ02ｨｪｨｹ0302ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ ｨ 08ｨｰ0208ｨｨｨｦ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ ｨｨ ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0902ｨｪ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ (ｨ :09=1:4). 0306 01ｨ ｨｪｨｪ04ｨｬ ｨｰ06ｨｬ060008ｨ 00ｨｨｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ04ｨｦ 06ｨ ｨｲ00ｨｬ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ｨｺ0502ｨｰ ﾂｨ ｨｰｨｺｨｨ ｨｨ 05ｨｺ09ｨｰ08ｨ 06ｨｺｨｮ050708ｨｪ0401 ｨｬ040302 ｨ 0405 30,98 ﾀ0,17 09ｨｬ 3, 01ｨｨｨ ｨｬ02ｨｰ08 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ (5,27 ﾀ0,14 ｨｬｨｬ) 070802090403ｨ 05 0706ｨｺｨ 04ｨ ｨｰ0205ｨｹ 0609ｨｪ0609ｨｪ06ｨｦ 0008ｨｮ070704 09 1,5 08ｨ 04ｨ, ｨ 01ｨｨｨ ｨｬ02ｨｰ08 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04 (4,22 ﾀ0,41 ｨｬｨｬ) 09 2,8 08ｨ 04ｨ. 0308ｨｨ 090407ｨｨ09ｨｺ02 ｨｨ04 09ｨｰｨ 02ｨｨ06ｨｪｨ 08ｨ 09060909ｨｰｨ ｨｪ06090502ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ ｨｮ 05ｨｰｨｨ01 07ｨ 02ｨｨ02ｨｪｨｰ0609 ｨｪ02 ｨｪｨ ｨ 050601ｨ 050609ｨｹ, ｨｺ0806ｨｬ02 ｨｰ060006, 090407090502ｨｪ06 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ02 090604ｨｪｨｨｨｺｨｪ060902ｨｪｨｨ07 0006090002ｨｪ0002ｨｪ06ｨｬ02ｨｪｨ. 07 09090201 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 07080201ｨｬ02ｨｰｨｪ04ｨｬ 040802ｨｪｨｨ02ｨｬ ｨｰｨ ｨｺ0302 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪｨ 00050200ｨｬ06ｨｪｨ 0608ｨ ｨｨｨｰ04. 05ｨｬ02ｨｴ02ｨｪｨｨ02 0005ｨ 04ｨｪ060006 07ｨ 0506ｨｺｨ ｨｺ0702080201ｨｨ 09 09080201ｨｪ02ｨｬ 090609ｨｰｨ 09ｨｨ0506 24,71 ﾀ1,02 ｨｬｨｬ. 01ｨ ｨ 050601ｨ 050609ｨｹ 090408ｨ 0302ｨｪｨｪ0602 04ｨ ｨｬ02010502ｨｪｨｨ02 070807ｨｬ06ｨｦ ｨｨ 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨ02ｨｦ 0408ｨ ﾂｨｺｨ ｨｪｨ 090902ｨｰ, ｨ ｨｰｨ ｨｺ0302 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0408ｨ ﾂｨｺｨ ｨｪｨ ｨ ｨｺｨｺ06ｨｬ0601ｨ 02ｨｨ06 ｨｨ ｨｺ06ｨｪ0902080002ｨｪ02ｨｨ06. 0308ｨｨ 0600ｨｰｨ 05ｨｹｨｬ0609ｨｺ0607ｨｨｨｨ 090407090502ｨｪ06 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 020501, 020006 00ｨｨ07020802ｨｬｨｨ07, 08ｨ 04ｨｬ04ｨｰ0609ｨｰｨｹ 0008ｨ ｨｪｨｨ02 0909020006 ｨｺ08ｨ 07, ｨ ｨｰｨ ｨｺ0302 070806ｨｬｨｨｨｪ02ｨｪ02ｨｨ07 09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ0602 ｨｰ020506 09 09080201ｨｪ02ｨｬ ｨｪｨ 2 ｨｬｨｬ, ｨｺ0806ｨｬ02 ｨｰ060006 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0902ｨｪ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ (ｨ :09=2:4). 0306 01ｨ ｨｪｨｪ04ｨｬ ｨｰ06ｨｬ060008ｨ 00ｨｨｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ04ｨｦ 06ｨ ｨｲ00ｨｬ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ｨｺ0502ｨｰ ﾂｨ ｨｰｨｺｨｨ ｨｨ 05ｨｺ09ｨｰ08ｨ 06ｨｺｨｮ050708ｨｪ0401 ｨｬ040302 090609ｨｰｨ 09ｨｨ05 27,6 ﾀ1,79 09ｨｬ 3, 01ｨｨｨ ｨｬ02ｨｰ08 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ (4,32 ﾀ0,12 ｨｬｨｬ) 070802090403ｨ 05 0706ｨｺｨ 04ｨ ｨｰ0205ｨｹ 09 0609ｨｪ0609ｨｪ06ｨｦ 0008ｨｮ070702 09 1,2 08ｨ 04ｨ, ｨ 01ｨｨｨ ｨｬ02ｨｰ08 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04 (2,97 ﾀ0,39 ｨｬｨｬ) 09 1,9 08ｨ 04ｨ. 0308ｨｨ 090407ｨｨ09ｨｺ02 ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 01ｨ ｨｪｨｪ06ｨｦ 0008ｨｮ070704 ｨｪｨ ｨ 050601ｨ 050609ｨｹ 09060909ｨｰｨ ｨｪ06090502ｨｪｨｨ02 0609ｨｰ0806ｨｰ04 040802ｨｪｨｨ07 09 09080201ｨｪ02ｨｬ 0106 0,87 ﾀ0,09, 0601ｨｪｨ ｨｺ06 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪ06 08ｨ 0903ｨｨ0802ｨｪｨｨ02 09050207060006 0707ｨｰｨｪｨ, 0202ｨｪｨｰ08ｨ 05ｨｹｨｪ0402 ｨｨ/ｨｨ05ｨｨ 07ｨ 08ｨ 0202ｨｪｨｰ08ｨ 05ｨｹｨｪ0402 06ｨｰｨｪ0609ｨｨｨｰ0205ｨｹｨｪ0402 ｨｨ/ｨｨ05ｨｨ ｨ ｨ 09060506ｨｰｨｪ0402 09ｨｺ06ｨｰ06ｨｬ04, 0706080600 050502ｨｺｨｰ08ｨｨ ﾂ0209ｨｺ06ｨｦ ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｨ 0706 0006090002ｨｪｨｮ ｨ 0405 127 ﾀ5,87 ｨｬｨｺ08, ｨｺ08ｨｨｨｰｨｨ ﾂ0209ｨｺｨ 07 ﾂｨ 09ｨｰ06ｨｰｨ ｨｨ09 ﾂ0204ｨｪ060902ｨｪｨｨ07 ｨｬ0205ｨｹｨｺｨ ｨｪｨｨｨｦ 0706 0006090002ｨｪｨｮ 37 ﾀ3,79 0102. 07 09090201 ｨ 0605ｨｹｨｪ0401 09 ｨｪ0204ｨｪｨ ﾂｨｨｨｰ0205ｨｹｨｪ04ｨｬ 09ｨｪｨｨ0302ｨｪｨｨ02ｨｬ 0609ｨｰ0806ｨｰ04 040802ｨｪｨｨ07 01ｨｨｨ 00ｨｪ0609ｨｰｨｨ080609ｨ ｨｪ 06ｨｰ00ｨｺ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ｨｺ0502ｨｰ ﾂｨ ｨｰｨｺｨｨ. 05ｨｬ02ｨｴ02ｨｪｨｨ02 0005ｨ 04ｨｪ060006 07ｨ 0506ｨｺｨ ｨｺ0702080201ｨｨ 09 09080201ｨｪ02ｨｬ 090609ｨｰｨ 09ｨｨ0506 22,39 ﾀ0,87 ｨｬｨｬ. 01ｨ ｨ 050601ｨ 050609ｨｹ 04ｨ ｨｬ02010502ｨｪｨｨ02 070807ｨｬ06ｨｦ ｨｨ 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨ02ｨｦ 0408ｨ ﾂｨｺｨ ｨｪｨ 090902ｨｰ, ｨ ｨｰｨ ｨｺ0302 09060108ｨｮ030209ｨｰ0902ｨｪｨｪ06ｨｦ 0802ｨ ｨｺ02ｨｨｨｨ 0408ｨ ﾂｨｺｨ ｨｪｨ ｨ ｨｺｨｺ06ｨｬ0601ｨ 02ｨｨ06 ｨｨ ｨｺ06ｨｪ0902080002ｨｪ02ｨｨ06; ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 020501, 020006 00ｨｨ07020802ｨｬｨｨ07, 08ｨ 04ｨｬ04ｨｰ0609ｨｰｨｹ 0008ｨ ｨｪｨｨ02 0909020006 ｨｺ08ｨ 07, ｨ ｨｰｨ ｨｺ0302 070806ｨｬｨｨｨｪ02ｨｪ02ｨｨ07 09 09ｨｰ02ｨｺ050609ｨｨ01ｨｪ0602 ｨｰ020506 09 09080201ｨｪ02ｨｬ ｨｪｨ 1 ｨｬｨｬ; ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0902ｨｪ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ (ｨ :09=2:3,5). 0306 01ｨ ｨｪｨｪ04ｨｬ ｨｰ06ｨｬ060008ｨ 00ｨｨｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ04ｨｦ 06ｨ ｨｲ00ｨｬ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ｨｺ0502ｨｰ ﾂｨ ｨｰｨｺｨｨ ｨｨ 05ｨｺ09ｨｰ08ｨ 06ｨｺｨｮ050708ｨｪ0401 ｨｬ040302 ｨ 0405 25,51 ﾀ0,17 09ｨｬ 3 ; 01ｨｨｨ ｨｬ02ｨｰ08 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ (3,53 ﾀ0,18 ｨｬｨｬ) ｨｨ 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04 (1,53 ﾀ0,12 ｨｬｨｬ) 010609ｨｰ06090208ｨｪ06 ｨｪ02 06ｨｰ05ｨｨ ﾂｨ 05ｨｨ09ｨｹ 06ｨｰ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｦ 0609ｨｪ0609ｨｪ06ｨｦ 0008ｨｮ070704 (3,53 ﾀ0,19 ｨｬｨｬ ｨｨ 1,52 ﾀ0,12 ｨｬｨｬ 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06). 0308ｨｨ 090407ｨｨ09ｨｺ02 ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 01ｨ ｨｪｨｪ06ｨｦ 0008ｨｮ070704 090407090502ｨｪ06 09060909ｨｰｨ ｨｪ06090502ｨｪｨｨ02 0609ｨｰ0806ｨｰ04 040802ｨｪｨｨ07 0106 0,97 ﾀ0,02, 06ｨｰ09ｨｮｨｰ09ｨｰ09ｨｨ02 01020002ｨｺｨｰ0609 07060507 040802ｨｪｨｨ07, 0706080600 050502ｨｺｨｰ08ｨｨ ﾂ0209ｨｺ06ｨｦ ﾂｨｮ0909ｨｰ09ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｨ 0706 0006090002ｨｪｨｮ 63 ﾀ2,87 ｨｬｨｺ08, ｨｺ08ｨｨｨｰｨｨ ﾂ0209ｨｺｨ 07 ﾂｨ 09ｨｰ06ｨｰｨ ｨｨ09 ﾂ0204ｨｪ060902ｨｪｨｨ07 ｨｬ0205ｨｹｨｺｨ ｨｪｨｨｨｦ 0706 0006090002ｨｪｨｮ 47 ﾀ5,63 0102. 06ｨ ｨｺｨｨｨｬ 06ｨ 08ｨ 0406ｨｬ, ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 0609ｨｰ0804ｨｬｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0608ｨ ｨｨｨｰ04 ｨｪｨ ｨ 050601ｨ 06ｨｰ0907 0708ｨｨ04ｨｪｨ ｨｺｨｨ 070608ｨ 0302ｨｪｨｨ07 ｨｺｨ ｨｺ ｨｨｨｪｨｰ08ｨ ｨ ｨｮ05ｨｹｨ ｨ 08ｨｪ06ｨｦ, ｨｰｨ ｨｺ ｨｨ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ. 05ｨｰ020702ｨｪｨｹ 0706090802030102ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ, ｨ 090606ｨｰ0902ｨｰ09ｨｰ0902ｨｪｨｪ06 ｨｨ 090408ｨ 0302ｨｪｨｪ0609ｨｰｨｹ ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ ｨｮ 05ｨｰｨｨ01 ｨ 0605ｨｹｨｪ0401 04ｨ 09ｨｨ0907ｨｰ 06ｨｰ 01ｨ 08ｨ ｨｺｨｰ0208ｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ060006 07080602020909ｨ (ｨｨｨｪ00ｨｨ05ｨｹｨｰ08ｨ ｨｰｨｨ09ｨｪ04ｨｦ ｨｨ05ｨｨ 00ｨｪ06ｨｦｨｪ04ｨｦ) 09 0005ｨ 04ｨｪｨｨ0202, ｨ ｨｰｨ ｨｺ0302 09ｨｮｨｬｨｬｨ 08ｨｪ060006 06ｨ ｨｲ00ｨｬｨ ｨｬ0700ｨｺ06ｨｰｨｺｨ ｨｪ060006 090601020803ｨｨｨｬ060006 0608ｨ ｨｨｨｰ04, ﾂｨｰ06 06ｨｰ08ｨ 0302ｨｪ06 09 ｨｰｨ ｨ 05. 1. 190
1302 04 06 01 06 01 08 09 05 01 04 03 05 06 08 06 05 06 06ｨ ｨ 05ｨｨ02ｨ 1. 05ｨ 09ｨｨ09ｨｨｨｬ0609ｨｰｨｹ 09ｨｰ020702ｨｪｨｨ ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ 06ｨｰ 09ｨｨ01ｨ 0609ｨｰ08060006 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ060006 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 0005ｨ 04ｨｪｨｨ0204 ｨｨ 06ｨ ｨｲ00ｨｬｨ 0200 ｨｬ0700ｨｺ06ｨｰｨｺｨ ｨｪ060006 090601020803ｨｨｨｬ060006 0P 09 080806ｨｬ02 ｨｰ060006, 07080609050203ｨｨ09ｨ 02ｨｰ0907 04ｨ 09ｨｨ09ｨｨｨｬ0609ｨｰｨｹ ｨｬ020301ｨｮ 090408ｨ 0302ｨｪｨｪ0609ｨｰｨｹ06 ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ ｨｨ 09ｨｰ020702ｨｪｨｹ06 ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ07 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ ｨｨ 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04, ｨ ｨｰｨ ｨｺ0302 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ02ｨｬ 090606ｨｰｨｪ060302ｨｪｨｨ07 ｨｨ01 01ｨｨｨ ｨｬ02ｨｰ080609. 06ｨ ｨｺ, ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 ｨ ｨｬｨ 0908060406ｨｬ 090606ｨｰｨｪ060302ｨｪｨｨ02 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ ｨｺ 01ｨｨｨ ｨｬ02ｨｰ08ｨｮ 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04 ｨ 040506 1,2:1, ｨｮ ｨ 0605ｨｹｨｪ0401 09 07080201ｨｬ02ｨｰｨｪ04ｨｬ 040802ｨｪｨｨ02ｨｬ ｨC 1,5:1, ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 ｨｪ02 090408ｨ 0302ｨｪｨｪ04ｨｬ 09ｨｪｨｨ0302ｨｪｨｨ02ｨｬ 0609ｨｰ0806ｨｰ04 040802ｨｪｨｨ07, ｨｺｨ ｨｺ ｨｨ 09 0609ｨｪ0609ｨｪ06ｨｦ 0008ｨｮ070702, 090609ｨｰｨ 09ｨｨ0506 2,3:1. 05ｨｰｨ ｨｰｨｨ09ｨｰｨｨ ﾂ0209ｨｺｨｨｨｦ ｨ ｨｪｨ 05ｨｨ04 080204ｨｮ05ｨｹｨｰｨ ｨｰ0609, 070605ｨｮ ﾂ02ｨｪｨｪ0401 01ｨ ｨｪｨｪ0401, 0706ｨｺｨ 04ｨ 05 ｨｰ0209ｨｪｨｮ06 06ｨ 08ｨ ｨｰｨｪｨｮ06 ｨｺ06080205050702ｨｨ06ｨｪｨｪｨｮ06 09090704ｨｹ ｨｬ020301ｨｮ 0706ｨｺｨ 04ｨ ｨｰ020502ｨｬ 0609ｨｰ0806ｨｰ04 040802ｨｪｨｨ07 ｨｨ 06ｨ ｨｲ00ｨｬ06ｨｬ ｨｬ0700ｨｺ06ｨｰｨｺｨ ｨｪ060006 090601020803ｨｨｨｬ060006 0608ｨ ｨｨｨｰ04 (r=-0,82), 01ｨｨｨ ｨｬ02ｨｰ0806ｨｬ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ (r=-0,85) ｨ ｨｰｨ ｨｺ0302 01ｨｨｨ ｨｬ02ｨｰ0806ｨｬ 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04 (r=-0,76). 000400020204 1. 030608ｨ 0302ｨｪｨｨ02 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ ｨｮ 07ｨ 02ｨｨ02ｨｪｨｰ0609 09 0609ｨｰ0804ｨｬｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0608ｨ ｨｨｨｰ04 ｨｪｨ ｨ 050601ｨ 02ｨｰ0907 09 16,7 % 0905ｨｮ ﾂｨ 0209. 2. 020507 ｨ 0605ｨｹｨｪ0401 09 0609ｨｰ0804ｨｬｨｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ04ｨｬｨｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0608ｨ ｨｨｨｰ04 01ｨ 08ｨ ｨｺｨｰ0208ｨｪ04 0708ｨｨ04ｨｪｨ ｨｺｨｨ 070608ｨ 0302ｨｪｨｨ07 ｨｺｨ ｨｺ ｨｨｨｪｨｰ08ｨ ｨ ｨｮ05ｨｹｨ ｨ 08ｨｪ06ｨｦ, ｨｰｨ ｨｺ ｨｨ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ. 3. 05ｨｰ020702ｨｪｨｹ 0706090802030102ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ 01ｨ 08ｨ ｨｺｨｰ0208ｨ 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ060006 07080602020909ｨ 09 0005ｨ 04ｨｪｨｨ0202 ｨｨ 09ｨｮｨｬｨｬｨ 08ｨｪ060006 06ｨ ｨｲ00ｨｬｨ ｨｬ0700ｨｺｨｨ01 ｨｰｨｺｨ ｨｪ02ｨｦ 0608ｨ ｨｨｨｰ04. 4. 000408ｨ 0302ｨｪｨｪ0609ｨｰｨｹ ｨｪｨ 08ｨｮ0302ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ0401 00ｨｮｨｪｨｺ02ｨｨｨｦ 04ｨ 09ｨｨ09ｨｨｨｰ 06ｨｰ 09ｨｰ020702ｨｪｨｨ ｨｮ090205ｨｨ ﾂ02ｨｪｨｨ07 01ｨｨｨ ｨｬ02ｨｰ08ｨ 0608ｨ ｨｨｨｰｨ 05ｨｹｨｪ06ｨｦ ﾂｨ 09ｨｰｨｨ 0408ｨｨｨｰ0205ｨｹｨｪ060006 ｨｪ020809ｨ ｨｨ 09020801ｨｪ02ｨｦ 0005ｨ 04ｨｪ06ｨｦ 0902ｨｪ04, ｨ ｨｰｨ ｨｺ0302 ｨｨ04ｨｬ02ｨｪ02ｨｪｨｨ07 090606ｨｰｨｪ060302ｨｪｨｨ07 ｨｨ01 01ｨｨｨ ｨｬ02ｨｰ080609. 09060603040806070408 1. 0804ｨｪｨ ｨ ｨ 0209 00.06. 02ｨｨｨ 00ｨｪ0609ｨｰｨｨｨｺｨ ｨｨ 0502 ﾂ02ｨｪｨｨ02 0609ｨｰ080401 09060907ｨ 05ｨｨｨｰ0205ｨｹｨｪ0401 04ｨ ｨ 06050209ｨ ｨｪｨｨｨｦ 0608ｨ ｨｨｨｰ04 ｨｮ 0102ｨｰ02ｨｦ / 00.06. 0804ｨｪｨ ｨ ｨ 0209, 00.08. 05ｨｮ08ｨｺ0609ｨ, 08.04. 04ｨｮｨｬｨ ｨｪｨｨ07040609// 000209ｨｰｨｪｨｨｨｺ 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨｨｨ. ｨC 2005. ｨC 01 2. ｨC 05. 11-14. 2. 09080609ｨｺｨｨｨｪｨ 08.08. 0906050204ｨｪｨｨ 0608ｨ ｨｨｨｰ04 / 08.08. 09080609ｨｺｨｨｨｪｨ - 00.: 000608, 2008. ｨC 05. 132-137. 3. 0206ｨ 0806ｨｬ0405ｨｹ09ｨｺｨｨｨｦ 08.06. 0308ｨｨ01ｨ ｨｰ06 ﾂｨｪ0402 07ｨ 04ｨｮ01ｨｨ ｨｪ0609ｨ ｨｨ ｨｨ01 09090704ｨｹ 09 04ｨ ｨ 06050209ｨ ｨｪｨｨ07ｨｬｨｨ 0005ｨ 04ｨｪｨｨ0204 ｨｨ 090502040606ｨｰ09060107ｨｴｨｨ01 07ｨｮｨｰ02ｨｦ /08.06. 0206ｨ 0806ｨｬ0405ｨｹ09ｨｺｨｨｨｦ, 06.06. 020208ｨ ｨ ｨｰ0609. - 00.: 00020100ｨｨ04, 1961. ｨC 288 09. 4. 05060506ｨｰｨ 080209ｨ 00.00. 0105ｨ 04ｨｪ0402 ｨ 06050204ｨｪｨｨ /00.00. 05060506ｨｰｨ 080209ｨ. ｨC 00ｨｨｨｪ09ｨｺ: 090205ｨ 08ｨｮ09ｨｹ, 1961. ｨC 05. 497-504. 5. 000208ｨｺｨｮ050609 06.06. 0805ｨｨｨｪｨｨ ﾂ0209ｨｺｨ 07 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨ07 / 06.06. 000208ｨｺｨｮ050609. ｨC 09ｨ 08ｨｹｨｺ0609: 09ｨ 08ｨｹｨｺ060909ｨｺｨｨｨｦ ｨｮｨｪｨｨ09020809ｨｨｨｰ02ｨｰ, 1966. ｨC 05. 265 ｨC 295. ｨC (ｨｺｨｪ. 1). 6. 06ｨ 08ｨ 090609ｨ 09.01. 08050200ｨｬ06ｨｪｨ 0608ｨ ｨｨｨｰ04: ｨｺ05ｨｨｨｪｨｨｨｺｨ, 01ｨｨｨ 00ｨｪ0609ｨｰｨｨｨｺｨ /09.01. 06ｨ 08ｨ 090609ｨ, 01.00. 09ｨ ｨｺｨｨｨｬ0609ｨ, 05.00. ﾁ0208ｨｪ0609//000209ｨｰｨｪｨｨｨｺ 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨｨｨ. ｨC 2008. ｨC 01 6. ｨC 05. 33 ｨC 36. 7. 060806ｨｪ 03.04. 05ｨ ｨ 06050209ｨ ｨｪｨｨ07 0408ｨｨｨｰ0205ｨｹｨｪ060006 07ｨｮｨｰｨｨ / 03.04. 060806ｨｪ. ｨC 09.:000302010605, 1955. ｨC 387 09. 8. 09ｨ ｨｺｨｨｨｬ0609ｨ 01.00. 05ｨｮｨ 070208ｨｨ0609ｨｰｨ 05ｨｹｨｪ04ｨｦ ｨ ｨ 0902020909 0608ｨ ｨｨｨｰ04 /01.00. 09ｨ ｨｺｨｨｨｬ0609ｨ // 000209ｨｰｨｪｨｨｨｺ 0600ｨｰｨ 05ｨｹｨｬ06050600ｨｨｨｨ. ｨC 2008. ｨC 05. 57 ｨC 59. 9. Das J.K. Orbital Abscess and Hemi-Occlusion of the Central Retinal Vein in a Child /J.K. Das, B.D. Choudhury, J.Medhi// Orbit. ｨC 2007. ｨC Vol. 26. ｨC P. 295-297. 10. Kiratli H.L. Acute ophthalmic artery obstruction secondary to subperiosteal abscess with retrobulbar phlegmonous infection /H.L. Kiratli, T.S. Kansu, U.L. Beden// Neuro-ophthalmology. ｨC 1998. ｨC Vol. 20 (3). ｨC P. 149-153. 191
132011, ｨｰ06ｨｬ 14, 014 ﾂ.2 (56) 0608000406 ﾁ0305080607 000302060802-09060209020106 ﾁ0305080607 00030506010608 070208 612.648-;617.7-053.32+615.849.19.+617.735-053.,32 08 03.07. 09ｨｨ08ｨｺｨｮｨｪ, 06.08. 0902080204060909ｨｺｨ 07, 05.08. 05060806ｨｺｨｨｨｪｨ, 2011. 02030406 0206080101020506060806 0403060601020308060606 010302020102010301010409 00 080407 0002030605080808 0809060106 ﾁ0305080808 090209050106000803 0804 08040400 03.07. 09ｨｨ08ｨｺｨｮｨｪ, 06.08. 0902080204060909ｨｺｨ 07, 05.08. 05060806ｨｺｨｨｨｪｨ 080407 000202ｨｰ09ｨｺｨ 07 ｨｺ05ｨｨｨｪｨｨ ﾂ02ｨｺｨ 07 ｨ 0605ｨｹｨｪｨｨ02ｨ 03, 00. 05ｨｨｨｬ00020806070605ｨｹ, 0804 080804ｨｬ, 07ｨｺ08ｨ ｨｨｨｪｨ THE EXPERIENCE OF DIAGNOSTICS OF A RETINOPATHY PREMATURETY NEWBORNS IN THE CRIMEAN REPUBLICAN ESTABLISHMENT 00CHILDREN'S CLINICAL HOSPITAL03 OF AR CRIMEA E.Birkun, T.Berezovskaya, S.Sorokina SUMMARY It was examinated 522 prematurity newborns. Debut of the active retinopathy of prematurity (ROP) were found in 136 children (26%) in postconception age from 30 to 39 weeks. The terminal stage had 31 patients. The time of the beginning of terminal stage was from 1 to 12 weeks past of foundation of the active ROP. The posterior ROP had 7 newborns. The high variability of the beginning of active ROP and aperients of terminal stage of ROP is important in planning of ophthalmological examinations of prematurity newborns. 020205000502 0205080101020506060806 0403060601020308060504 0103020201020103010609 0205060307 00 080407 0002060608 ﾁ08 0809050105 ﾁ0108 0905080804010803 0804 08040600 02.07. 090608ｨｺｨｮｨｪ, 06.08. 0902080204060909ｨｹｨｺｨ, 05.08. 05060806ｨｺ06ｨｪｨ 040305070003 02ｨ 09ｨｰ020302ｨｪ06 522 ｨｪ020106ｨｪ060302ｨｪｨｨ01 ｨｪ060906ｨｪｨ 0806010302ｨｪｨｨ01. 0202ｨ 06ｨｰ ｨ ｨｺｨｰｨｨ09ｨｪ0607 0802ｨｰｨｨｨｪ0607ｨ ｨｰ0607 ｨｪ020106ｨｪ060302ｨｪｨｨ01 (0401) 09ｨｨ07090502ｨｪ06 ｨｮ 136 0106ｨｰ02ｨｦ (26%) ｨｮ 070609ｨｰｨｺ06ｨｪ02020702ｨｨ06ｨｪｨｪ06ｨｬｨｮ 09060206 090601 30 0106 39 ｨｰｨｨ0301ｨｪ0609. 03060806000609ｨ 09ｨｰｨ 010607 0401 08ｨ 0409ｨｨ05ｨ 0907 ｨｮ 31 ｨｪ02ｨｬ06090507. 060208ｨｬ06ｨｪｨｨ 08060409ｨｨｨｰｨｺｨｮ 070608060006090607 09ｨｰｨ 010607 09ｨ 08ｨｹ0708ｨｮ06ｨｰｨｹ 090601 1 0106 12 ｨｰｨｨ0301ｨｪ0609 0706090507 09ｨｨ07090502ｨｪｨｪ07 ｨ ｨｺｨｰｨｨ09ｨｪ0607 0401. 05ｨ 01ｨｪ07 0401 09ｨｨ07090502ｨｪｨ ｨｮ 7 07ｨ 02ｨｨ02ｨｪｨｰ0609. 00ｨｨ0906ｨｺｨ 09ｨ 0806ｨ ｨ 0205ｨｹｨｪ0609ｨｰｨｹ ｨｰ0208ｨｬ06ｨｪ0609 0706 ﾂｨ ｨｰｨｺｨｮ ｨ ｨｺｨｰｨｨ09ｨｪ0607 0401 ｨｰｨ 0607 070608060006090607 09ｨｰｨ 010607 ｨｬｨ 02 090205ｨｨｨｺ02 04ｨｪｨ ﾂ02ｨｪｨｪ07 0708ｨｨ 0705ｨ ｨｪｨｮ09ｨ ｨｪｨｪ06 0600ｨｰｨ 05ｨｹｨｬ0605060006 ﾂｨｪｨｨ01 06ｨ 09ｨｰ020302ｨｪｨｹ ｨｴ060106 0401. 080506 ﾂ02090402 09050609ｨ : ｨｪ020106ｨｪ060302ｨｪｨｪ0402 ｨｪ0609060806030102ｨｪｨｪ0402, 0802ｨｰｨｨｨｪ0607ｨ ｨｰｨｨ07 ｨｪ020106ｨｪ060302ｨｪｨｪ0401, 070608060006090402 09ｨｰｨ 01ｨｨｨｨ 0802ｨｰｨｨｨｪ0607ｨ ｨｰｨｨｨｨ ｨｪ020106ｨｪ060302ｨｪｨｪ0401, 05ｨ 040208ｨｺ06ｨ 00ｨｮ050702ｨｨ07 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ. 0402ｨｰｨｨｨｪ0607ｨ ｨｰｨｨ07 ｨｪ020106ｨｪ060302ｨｪｨｪ0401 (0401) ｨC ｨｰ070302050602 09ｨ 040607080605ｨｨ000208ｨ ｨｰｨｨ09ｨｪ0602 04ｨ ｨ 06050209ｨ ｨｪｨｨ02, ｨｪ02080201ｨｺ06 0708ｨｨ09060107ｨｴ0202 ｨｺ ｨｨｨｪ09ｨ 05ｨｨ01ｨｪ0609ｨｰｨｨ 0706 040802ｨｪｨｨ06 ｨｨ 0905020706ｨｰ02 ｨｮ 0102ｨｰ02ｨｦ 09ｨ ｨｬ060006 08ｨ ｨｪｨｪ020006 09060408ｨ 09ｨｰｨ [1, 8, 14]. 0308ｨ 09ｨｨ05ｨｹｨｪ04ｨｦ 070601010601 ｨｺ 070806ｨ 0502ｨｬ02 08ｨ ｨｪｨｪ020006 090407090502ｨｪｨｨ07 ｨｨ 09090602090802ｨｬ02ｨｪｨｪ060006 0502- ﾂ02ｨｪｨｨ07 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 0706040906050702ｨｰ 09060108ｨ ｨｪｨｨｨｰｨｹ 040802ｨｪｨｨ02 ｨ 0605ｨｹ03ｨｨｨｪ09ｨｰ09ｨｮ 0102ｨｰ02ｨｦ 09 0401 [2, 4, 9, 12]. 05060005ｨ 09ｨｪ06 05ｨｨｨｰ0208ｨ ｨｰｨｮ08ｨｪ04ｨｬ 01ｨ ｨｪｨｪ04ｨｬ 0401 06ｨｰ05ｨｨ ﾂｨ 02ｨｰ ｨ 0605ｨｹ03ｨ 07 09ｨ 08ｨｨｨ ｨ 0205ｨｹｨｪ0609ｨｰｨｹ 090806ｨｺ0609 090604ｨｪｨｨｨｺｨｪ060902ｨｪｨｨ07, 0105ｨｨｨｰ0205ｨｹｨｪ0609ｨｰｨｨ ｨｰ02 ﾂ02ｨｪｨｨ07 ｨｨ 08ｨ 0409ｨｨｨｰｨｨ07 070608060006090401 000608ｨｬ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 [3, 5, 6, 7, 10]. 000205ｨｹ: 06070802010205ｨｨｨｰｨｹ ﾂｨ 09ｨｰ06ｨｰｨｮ ｨｨ 090806ｨｺｨｨ 090604ｨｪｨｨｨｺｨｪ060902ｨｪｨｨ07 ｨ ｨｺｨｰｨｨ09ｨｪ06ｨｦ 0401 ｨｨ 070608060006090401 000608ｨｬ 0706 01ｨ ｨｪｨｪ04ｨｬ 09ｨｺ08ｨｨｨｪｨｨｨｪ00ｨ ｨｪ020106ｨｪ060302ｨｪｨｪ0401 0102ｨｰ02ｨｦ 09 ｨｮ09050609ｨｨ0701 080407 0002080903 09 0804 080804ｨｬ. 000806030406080904 06 000306020204 030601 01ｨｨｨｪｨ ｨｬｨｨ ﾂ0209ｨｺｨｨｨｬ ｨｪｨ ｨ 05060102ｨｪｨｨ02ｨｬ ｨｪｨ 010601ｨｨ05ｨｨ09ｨｹ 522 ｨｪ020106ｨｪ060302ｨｪｨｪ0401 0802ｨ 02ｨｪｨｺｨ (219 ｨｬｨ 05ｨｹ ﾂｨｨｨｺ0609 ｨｨ 203 01020906 ﾂｨｺｨｨ), 0806030102ｨｪｨｪ0401 09 090806ｨｺｨｨ 06ｨｰ 26 0106 34 ｨｪ02010205ｨｨ 000209ｨｰｨ 02ｨｨｨｨ, 09 09020906ｨｬ 06ｨｰ 847 0106 150000, 070806010601ｨｨ0903ｨｨ01 0502 ﾂ02ｨｪｨｨ02 09 06ｨｰ01020502ｨｪｨｨｨｨ ｨｪ020106ｨｪ060302ｨｪｨｪ0401 ｨｪ0609060806030102ｨｪｨｪ0401 080407 0002080903 00.05ｨｨｨｬ0002080607060507, ｨ ｨｰｨ ｨｺ0302 ｨC ｨ ｨｬｨ ｨｮ05ｨ ｨｰ0608ｨｪ0402 07ｨ 02ｨｨ02ｨｪｨｰ04, 0709050706ｨｴｨｨ020907 0008ｨｮ070706ｨｦ 08ｨｨ09ｨｺｨ 0706 0401 (ｨｮ ﾂｨｨｨｰ0409ｨ 05ｨｨ09ｨｹ 090209 ｨｨ 090806ｨｺｨｨ 000209ｨｰｨ 02ｨｨｨｨ 0708ｨｨ 0806030102ｨｪｨｨｨｨ). 0202ｨｰｨｨ 09 090407090502ｨｪｨｪ06ｨｦ ｨ ｨｺｨｰｨｨ09ｨｪ06ｨｦ 0401 ｨｪｨ 010601ｨｨ05ｨｨ09ｨｹ 070601 01ｨｨｨｪｨ ｨｬｨｨ ﾂ0209ｨｺｨｨｨｬ ｨｪｨ ｨ 05060102ｨｪｨｨ02ｨｬ 0106 070605ｨｪ060006 08020008020909ｨ 04ｨ ｨ 06050209ｨ ｨｪｨｨ07 ｨｨ05ｨｨ 07020802010601ｨ 020006 09 07060806000609ｨｮ06 09ｨｰｨ 01ｨｨ06, ｨ ｨｰｨ ｨｺ0302 09 070609050206070208ｨ 02ｨｨ06ｨｪｨｪ04ｨｦ 070208ｨｨ0601 0706090502 05ｨ 040208ｨｺ06ｨ 00ｨｮ050702ｨｨｨｨ ｨ 09ｨ 09ｨｺｨｮ050708ｨｪ0401 0406ｨｪ 0902ｨｰ ﾂｨ ｨｰｨｺｨｨ. 0209ｨｬ06ｨｰ08 0005ｨ 04ｨｪ060006 01ｨｪｨ 070806090601ｨｨ050907 09 0706ｨｬ06ｨｴｨｹ06 ｨｪ02070807ｨｬ060006 ｨ ｨｨｨｪ06ｨｺｨｮ050708ｨｪ060006 0600ｨｰｨ 05ｨｹｨｬ0609ｨｺ0607ｨ Heine SIGMA 150 ｨｨ ｨ 09000208ｨｨ ﾂ0209ｨｺ06ｨｦ 05ｨｮ0704 28 01ｨｨ0607ｨｰ08ｨｨｨｦ, ｨｪｨ ｨｮ080609ｨｪ02 ｨｬｨ ｨｺ09ｨｨｨｬｨ 05ｨｹｨｪ060006 ｨｬｨｨ0108ｨｨｨ 04ｨ, 010609ｨｰｨｨ00ｨ 02ｨｬ060006 09 0706ｨｬ06ｨｴｨｹ06 0008ｨ ｨｺ02ｨｨ06ｨｪｨｪ0401 ｨｨｨｪ09ｨｰｨｨ05050702ｨｨｨｦ ｨｺ06ｨｬｨ ｨｨｨｪｨ 02ｨｨｨｨ 08ｨ 09ｨｰ0906080609 08ｨｰ080607ｨｨｨｪｨ 0, 1% ｨｨ 06080607ｨｨｨｺｨ ｨｬｨｨ01ｨ 0,5%. 04030507090506080604 06 0609 02090507040203010603 0604 522 0609ｨｬ06ｨｰ0802ｨｪｨｪ0401 0102ｨｰ02ｨｦ 0102ｨ 06ｨｰ ｨ ｨｺｨｰｨｨ09ｨｪ06ｨｦ 0401 090407090502ｨｪ ｨｮ 136 0102ｨｰ02ｨｦ (26%), ｨｨ04 ｨｪｨｨ01 ｨ 040506 52 01020906 ﾂ02ｨｺ ｨｨ 84 ｨｬｨ 05ｨｹ ﾂｨｨｨｺ0609 09 070609ｨｰｨｺ06ｨｪ02020702ｨｨ06ｨｪｨｪ06ｨｬ 09060408ｨ 09ｨｰ02 06ｨｰ 30 0106 39 ｨｪ02010205ｨｹ (09 09080201ｨｪ02ｨｬ 34,3 ｨｪ02010205ｨｨ) ｨｨ05ｨｨ ﾂ02080204 4,67 (06ｨｰ 3 0106 9) ｨｪ02010205ｨｨ 0706090502 0806030102ｨｪｨｨ07 0802ｨ 02ｨｪｨｺｨ. 05080201ｨｨ 0102ｨｰ02ｨｦ 09 ｨ ｨｺｨｰｨｨ09ｨｪ06ｨｦ 0401 ｨ 040506 12 ｨ 05ｨｨ04ｨｪ02020609 ｨｨ 2 ｨｰ0806ｨｦｨｪｨｨ, ﾂｨｰ06 090609ｨｰｨ 09050702ｨｰ 21,3%. 07 09090201 ｨ 0605ｨｹｨｪ0401 ｨｪｨ ｨ 050601ｨ 050609ｨｹ 0109ｨｮ09ｨｰ060806ｨｪｨｪ0202 070608ｨ 0302ｨｪｨｨ02. 0201ｨｪｨ ｨｺ06, 09ｨｰ06ｨｨｨｰ 06ｨｰｨｬ02ｨｰｨｨｨｰｨｹ, ﾂｨｰ06 ｨｮ 11 0102ｨｰ02ｨｦ (9,5% 06ｨｰ 06ｨ ｨｴ020006 ｨｺ0605ｨｨ ﾂ0209ｨｰ09ｨ ) 07080602020909 ｨｪｨ 192