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1 Chuo Sangio Times...Contents Optos Optos California OASIS Vector Vision ESV-3000 Luneau Technology RO8000 Daytona Keratograph 5M AngioVue AngioVue C-Quant

2 H27 Optos Optos 200Tx Daytona Tx Daytona

3 California > % > > 4 AF FA IA 1 > FA IA 227AIBZI IA AF FA

4 > > B1X ESV-3000 > > LED 85cd/m 2 > (Chart 1) (Chart 2) Log > E ETDRS > Chart 1 ETDRS ETDRS E ETDRS ESV B1X

5 2012 Luneau Luneau Technology Briot Weco Visionix Rodenstock President & CEO RO8000 Marc Abitbol, PhD Luneau Technology homepage: RO8000 Rodenstock RO LED RO RO1000 RO , RO5000 RO8000 LED LED RO RO8000

6 RO8000 RO5000 LED RO8000 RO8000 3D RO RO5000 Luneau Technology operations RO ,000 LED Red Green Blue Yellow 1 LED LED LED Yellow

7 Optos Daytona II image eye clinic visual eye clinic CCD visual eye clinic 2007 visual eye clinic OCT Optos Daytona Optos Daytona Optos Daytona 1 80% Optos Daytona Optos Daytona Optos Daytona

8 Keratograph 5M 2012 ESCRS Prof. Stephen Klyce Keratograph 5MK5M NIKBUT TMH 1 TMH NIKBUT (Break-Up Time: BUT) TSAS (Tear Stability Analysis System) (Tear Meniscus Height: TMH) 1 TMH TMH 0.08 mm Keratograph 5M K5M (Meibomian Gland Dysfunction: MGD) K5M 1 TMH 1 NIKBUT Non-Invasive Keratograph Break-Up Time 2 3 TMH NIKBUT NIKBUT Break-up 2 NIKBUT

9 K5M K5M 3 Keratograph 5M TMH NIKBUT NIKBUT K5M Break-up NIKBUT TMH BUT 2 4 K5M K5M Aqueous Deficient Dry Eye: ADDE Evaporative Dry Eye: EDE MGD 4 K5M TMH NIKBUT (Tear Film Oriented Diagnosis: TFOD) (Tear Film Oriented Therapy: TFOT) 1. Koh S et al. Effect of noninvasive tear stability assessment on tear meniscus height. Acta Ophthalmologica. 93:e135- e139, Koh S et al. Upper and lower difference in tear film stability and meibomian glands in dry eye. Eye & Contact Lens. in press

10 OCT angiography OCT angiography OCTA OCT OCTA CNV block CNV CNV OCTA CNV CNV CNV RPE Type 1 Type 2 Type 1 CNV 1 2OCT RPE 2 Choroid Capillary CNV Type 2 CNV CNV RPE CNV 3 Type 2 CNV VEGF CNV 4 3 Outer Retina CNV Type 2 1 Choroid Capillary CNV 4 Outer Retina CNV Type 2

11 SSADA OCT AngioVue 10 OCT Angiography OCT decorrelation Optovue RTVue XR Avanti AngioVue OCT Angiography OCT 1 AngioVue AngioFlow En Face AngioFlow 100 µm OCT Angiography AngioVue Ishibazawa AJO 2015) FAG 3 2 VEGF AngioVue 1967 Henkind IOVS 1967 Radial Peripapillary Capillary AngioVue AngioFlow vessel density index* P= OCT En Face 4 cleavage AngioVue En Face Chihara: JAMA Ophthalmology in press OCT Angiography 3 RPC 2 AngioVue AngioFlow 2 AngioVue 4 cleavage 3 βversion

12 C-Quant Solomon 57% 11% QOV 6% 1 QOV C-Quant C-Quant Cataract Quantifier Pentacam 2 log(s) 0.3 log(s) 2 Q Esd 2 2 log Esd Estimated Standard Deviation log 0.87 Esd 0.06 log 0.87 ±

13 0.9 log(s) log(s) log(s) 2 IOL Cervino log(s) C-Quant LASIK 1.0 TJTP van den Berg, PhD. (Associate Professor at Netherlands Institute for Neuroscience, Royal Academy) Kerry D. Solomon et al. LASIK World Literature Review : Quality of Life and Patient Satisfaction. American Academy of Ophthalmology. Volume 116, Issue 4, April 2009, Pages Van Den Berg et al. History of ocular straylight measurement: A review. Zeitschrift fur Medizinische Physik 2013;23: Van Den Berg et al. Straylight Effects with Aging and Lens Extraction. American Journal of Ophthalmology Sep;144(3): A Cerviño et al. Performance of the compensation comparison method for retinal straylight measurement: effect of patient s age on repeatability. British Journal of Ophthalmology. 2008;92; Franssen L et al. Pupil size and retinal straylight in the normal eye. Investigative Ophthalmology & Visual Science May. Vol. 48, No Van den Berg et al. Straylight measurements as an indication for cataract surgery. Journal of Cataract and Refractive Surgery :

14 Hola! ESCRS ESCRS 20 Optovue Optovue OCT RTVue GCC 2009 ivue OCT AngioVue FAG ICG OCT Angiography RTVue XR Avanti OCT Angiography Optovue 24

15 6824 Washington Ave. S, Eden Prairie, MN phone: homepage: Bayview Dr, Fremont, CA phone: homepage: 2 R ROGET BONNET PONT DE L'ARCHE phone: homepage: Marcus Avenue C105, Lake Success, NY phone: homepage: West Allen Avenue, San Dimas, CA phone: homepage: Livingston Rd. Ste.E, Greenville, Ohio phone: homepage: Münchholzhäuser Str. 29 D Wetzlar phone: homepage: Augustaanlage 32 D Mannheim phone: +49-(0) homepage: Queensferry House Carnegie Campus Enterprise Way Dunfermline Scotland KY11 8GR phone: homepage: Chimney Rock Road Suite 110, Houston, Texas phone: homepage:

16 Tel Fax Tel Fax Tel Fax Tel Fax /8300

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