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1 (Ko ch ro Matsuno) 1 1) 1.5 $-$

2 2 $-$ 1842 $-$ $-$ $-$ $-$ $-$ $-$ 53

3 54 2,3) ( ) ( ) 1824 ( ) ( ). ATP ATP ADP 5 3 $\mathrm{x}\mathrm{l}\mathrm{o}^{-\rceil}$ ATP 1 $0$ 5 3 $\mathrm{x}\mathrm{l}\mathrm{o}^{-1}$ 1 $0$ $\mathrm{e}$ m $\Delta \mathrm{t}\mathrm{m}(\approx\hslash/\mathrm{e}_{\mathrm{m}}$ ; $\hslash$

4 55 $\mathrm{o}$ $\mathrm{x}\mathrm{l}\mathrm{o}$ 2\mbox{\boldmath $\pi$} ) 1 5 $-\rceil$ 3 $\mathrm{x}\mathrm{l}\mathrm{o}^{-1}$ $\mathrm{e}_{\mathrm{m}}$ $\mathrm{k}$ ) ATP ( ; ) ATP - \yen -

5 $0$ $\mathrm{k}$ 56

6

7 \mathrm{m}_{\text{ }}$ 58 5) 20\sim 1 $00\mathrm{K}$ $\mathrm{k}$ 200 $-\mathrm{c}\mathrm{h}2^{-}$ $\mathrm{c}\mathrm{h}3$ ( 3. $\mu 4 $\mathrm{c}\mathrm{m}^{-1}$ 2955 ) 6-9) - 10,11) 42 $\square$ 4. 2

8 59 12) 13) 4. 3 $\square$ 14) 2000m oC $350^{\mathrm{o}}\mathrm{C}$ 24MPa 00C.\Xi $250^{\mathrm{o}}\mathrm{C}$ ) $-$ 16) $1\eta$ $\square$

9 $\square$ $-\text{ }$ 18-20) 5 60

10 ts Swens, odynami the dge vers ty \mathrm{o}\mathrm{r}$ the ty of the. ces. ve 61 21) $\text{ } \text{ ^{ } _{ }}$ [ ] 1. Matsuno, K., $Protobio/og\mathrm{y}.\cdot$ Phys $ic\mathrm{a}/b\mathrm{a}sis$ of $Bio/og\gamma$, CRC Press (1989) 2. Matsuno, K. $l$ R., Thermodynami cs present progress mode and $\mathrm{i}\mathrm{g}\mathrm{i}\mathrm{n}$ ro le ctext of the or 1 $BioS_{\mathrm{J}}/stems51$, (1999). $\mathrm{b}\mathrm{i}$ $\dagger $\mathrm{e}\mathfrak{n}\epsil$ 3. Matsuno, K., cs rgence of energy csumers, $BioS\gamma stems$ 42, (1997). $\mathrm{i}\mathrm{l}\mathrm{i}$ 4. Matsuno, K., Ce 11mot as an entangl ed quantum coherence. $BioS_{\mathrm{Y}}stems$ 51, (1999). 5. Brack, A. (Ed. ), $\Gamma hemo/ecu/\mathrm{a}r$ Or of $Life:Assemb/ing$ Pieces of the $igir \mathrm{s}$ $Puzz/\mathrm{e}$, Cambr Un Press (1998). $\mathrm{i}\mathrm{a}\mathrm{r}$ $0\dagger \mathrm{i}$ 6. Ch, J. E. \dagger The $igir \mathrm{s}\angle jfe$ nature and evolut nterste 1lar Or $\Xi vo/$. $Bios\rho here27$, (1997).

11 nterste $\mathrm{g}\mathrm{r}\mathrm{a}\mathrm{i}\mathrm{n}\mathrm{s}$ as of. J. ne J. $\mathrm{l}\mathrm{i}$ spersa de T. $\mathrm{e}\mathrm{n}\mathrm{v}\mathrm{i}$ rments: \mathrm{e}$ step gn ng :Are ple $\mathrm{l}\mathrm{i}\mathrm{p}\mathrm{i}\mathrm{d}$ synthes. ne synthes \mathrm{o}\mathrm{r}\mathrm{m}\mathrm{i}\mathrm{c}$ and ne nterste matter se1\dagger enough? ngs ngs metastab mit of 01\mathrm{i}\mathrm{g}\mathrm{o}\mathrm{p}\mathrm{e}\mathrm{p}\mathrm{t}\dot{ }$ des evolut under chemi gogl ary organ earth a nterstel \mathrm{b}\mathrm{i}$ oorgan ng ne lated hydrotherma hydrotherma \mathrm{r}\mathrm{a}\mathrm{c}\mathrm{t}\mathrm{o}\mathrm{r}\mathrm{y}$ a \dagger s cs 62 $\mathrm{i}\mathrm{s}\mathrm{s}_{l}$ $\mathrm{i}\dagger 7. Pendlet, Y. J., Detect $\mathrm{i}\mathrm{c}$ of organ [ar $\mathrm{g}\mathrm{r}\mathrm{a}\mathrm{i}\mathrm{n}\mathrm{s}$. Origins $Life\Xi vo/$. $Bios\rho here27$, (1997). 8. Greenberg, J. M.,, A., Mendoza-Gomez, C. X., Schutte, W. A., and $\mathrm{i}\mathrm{n}\mathrm{e}\mathrm{s}$ Gerak, P. $\mathrm{g}\mathrm{r}\mathrm{a}\mathrm{i}\mathrm{n}$ A., Approach the 1[ar $\mathrm{i}\mathrm{c}\mathrm{r}\mathrm{e}\dagger compent. Astrophys. J. 455, Ll (1995). 9. Greenberg, J. M., and Krueger, F. R., $0\dagger From the \dagger ormat $\mathrm{o}\mathrm{t}$ $\mathrm{i}\mathrm{z}\mathrm{a}\mathrm{t}\mathrm{i}$ 1lar dust to the thermodynami cs -organ cometary $0\dagger 1\mathrm{i}\dagger \mathrm{e} \mathrm{s}$ $10^{25}\mathrm{c}\mathrm{h}\mathrm{a}\mathrm{n}\mathrm{c}\mathrm{e}\mathrm{s}$ $\mathrm{i}\mathrm{g}\mathrm{i}\mathrm{n}\mathrm{s}$ seeds or Or igins $Life\Xi vo/$. $Bios\rho here26$, (1996). 10. Cor 1 B., et $\mathrm{a}/$, $\mathrm{r}\mathrm{i}\dagger \mathrm{t}$ $\mathrm{s}\mathrm{p}\mathrm{r}\mathrm{i}$ Submar thermal the Ga lapagos. Science 203, (1979) $\mathrm{a}/$ $0\dagger$ 11. Edmd, J. M., et., Chemi stry $\mathrm{i}\uparrow \mathrm{i}\mathrm{c}\mathrm{r}\mathrm{i}$ $\mathrm{s}\mathrm{p}\mathrm{r}\mathrm{i}$ hot the East Pac se $\mathrm{i}\mathrm{r}\mathrm{e}\mathrm{f}\mathrm{f}\mathrm{l}\mathrm{u}\dot{\mathrm{e}}\mathrm{n}\mathrm{t}\mathrm{d}\mathrm{i}$ and the 1. Nature 297, (1982). 12. Toyozawa, $1\mathrm{t}\mathrm{i}$ $\mathrm{i}\mathrm{s}\mathrm{o}\dagger$ Y., Mu photosynthes le compounds the $\mathrm{i}\mathrm{g}\mathrm{i}\mathrm{n}$ or 1 the earth. $d$ Rhys. Soc. $/\rho n66$, (1997). 13. Matsuno, K., $\mathrm{i}\mathrm{v}\mathrm{e}$ $\mathrm{c}\mathrm{s}$ $\mathrm{p}\mathrm{r}\mathrm{i}$ $\mathrm{b}\mathrm{i}11\mathrm{i}$ Boltzmann s dynami the about 3. 8 years ago. I $\mathrm{n}:chemic\mathrm{a}/\xi vo/uti$ :Phys $ics$ $\mathit{0}r/gi\prime n$ of the and $\Xi vo/uti$ of $\angle ife$ (Chela-Flores, J. &Raul, F. (Eds. )) Kluwer (1996), pp Matsuno, K., $\mathrm{p}\mathrm{r}\mathrm{i}\mathrm{n}\mathrm{c}\mathrm{i}$ $0\uparrow \mathrm{a}$ Ades \dagger low $\mathrm{s}\mathrm{i}\mathrm{m}\mathrm{u}\mathrm{l}\mathrm{a}\mathrm{t}\mathrm{i}$ $\mathrm{i}\mathrm{o}\mathrm{t}\mathrm{i}\mathrm{c}$ reactor preb $\mathrm{u}\mathrm{t}\mathrm{i}$ evol Origino 25, (1997). $V/v\mathrm{a}$ 15. [ma, E., et $\mathrm{a}/$., $\mathrm{i}\mathrm{c}$ Autocatal yt $\mathrm{i}\mathrm{s}$ $\mathrm{o}\mathrm{l}\mathrm{i}$ yc $\mathrm{s}\mathrm{i}\mathrm{m}\mathrm{u}$ lated submar hydrothermal system. Or igin $Li\mathrm{f}e\Xi vo/$. $Biosh\rho ere29$, (1999). $\mathrm{f}\mathrm{i}\mathrm{x}\mathrm{a}\mathrm{t}\mathrm{i}$ $\mathrm{d}\mathrm{i}\mathrm{o}\mathrm{x}\mathrm{i}$ $0\dagger \mathrm{i}\dagger \mathrm{e}$ 16.Russell, M. J., and Hall, A. J., The emergence \dagger rom r $\mathrm{l}\mathrm{p}\mathrm{h}\mathrm{i}$ $\mathrm{p}\mathrm{h}$ mosu bubbles at asubmar hydrotherma 1redox and rt. $d$ $\theta eo/$. Soc. Ld 154, $\mathrm{l}\mathrm{m}\mathrm{a}\mathrm{i}$ 17., E., et $\mathrm{a}/$., $0\mp Elgat $\mathrm{s}\mathrm{i}\mathrm{m}\mathrm{u}$ submar ne hydrothermal system. $Sc/ence283$, (1999). $\mathrm{i}\mathrm{s}_{l}$ 18. Ferr P., $\mathrm{i}\mathrm{o}\mathrm{t}\mathrm{i}\mathrm{c}$ Chemi cal markers of preb stry l systems. $\mathit{0}r/gins\angle ife\xi vo/$. $Bios\rho here22$, (1992). $\mathrm{m}\mathrm{c}\mathrm{c}\mathrm{o}\mathrm{l}\mathrm{l}\mathrm{o}\mathrm{m}_{\mathrm{i}}$ 19. M., et $\mathrm{a}/$. $,$ $\mathrm{i}\mathrm{s}$ $\mathrm{i}\mathrm{t}\mathrm{i}$ hydrotherma 1cd by $\mathrm{i}\mathrm{o}\mathrm{n}\mathrm{s}$ Fi $\mathrm{s}\mathrm{c}\mathrm{h}\mathrm{e}\mathrm{r}-\mathrm{t}\mathrm{r}\mathrm{o}\mathrm{p}\mathrm{s}\mathrm{c}\mathrm{h}$-type react $\mathit{0}r/ginsl/fe\xi vo/$. $Bios\rho here29$, (1999). 20. Terada, R., et $\mathrm{a}/$., of carb de 1 $\mathrm{i}\mathrm{s}\mathrm{o}+\dagger $\mathrm{i}\mathrm{c}\mathrm{a}\mathrm{c}\mathrm{i}\mathrm{d}\mathrm{s}$ synthes acet. $V/v\mathrm{a}$ Or igino 27, (1999). $\mathrm{m}\mathrm{a}\dot{\lrcorner}\mathrm{o}\mathrm{r}$ 21.Matsuno, K., Csumer power as the force. $\iota/$. $\Gamma heor$. $Bio/$. $173_{1}$ (1995).

40 $\mathrm{e}\mathrm{p}\mathrm{r}$ 45

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