To establish a local therapy of periodontitis by using minocycline HCl, a series of studies has been conducted. The present study was to re-confirm th
|
|
- あきひさ かせ
- 5 years ago
- Views:
Transcription
1 Local Administration of Minocycline for Periodontitis Double Blind Comparative Study of LS-007 Yoji MURAYAMA1), Yoshio NOMURA1), Akira YAMAOKA2), Masatoshi UEDA2), Toshio HORP), Masato MINABE3), Toshio UMEMOTO4), Isao ISHIKAWA5), Ryoji URAGUCHP), Kazue UENO6), Kunitomo WATANABE6) and Nobuya OGAWA7) 1) Department of Periodontology and Endodontology, Okayama University Dental School Chief: Prof. Yoji MURAYAMA) ( 2) Department of Periodontology, Osaka Dental University Chief: Prof. Akira YAMAOKA) ( 3) Department of Periodontology, Kanagawa Dental College Chief: Prof. Toshio HORI) ( 4) Department of Oral Microbiology, Kanagawa Dental College Chief: Prof. Toshio UMEMOTO) ( 5) Department of Periodontology, School of Dentistry, Tokyo Medical and Dental University Chief: Prof. Isao ISHIKAWA) ( 6) Institute of Anaerobic Bacteriology, Gifu University School of Medicine Chief: Prof. Kazue UENO) ( 7) Deptartment of Pharmacology, Ehime University School of Medicine Chief: Prof. Nobuya OGAWA) (
2 To establish a local therapy of periodontitis by using minocycline HCl, a series of studies has been conducted. The present study was to re-confirm the results of the previous investigations, and objectively evaluate the usefulness of minocycline HCl ointment, LS-007. In this double blind study the ointment base of LS-007 (PL) was used as a control. The change of bacteria in periodontal pockets after administration of LS-007 was also examined. Results are stated below. 1. The LS-007 group showed significant superiority to the PL group in clinical effectiveness, overall efficacy, usefulness, improvement rate, and usefulness rate. 2. In the improvement of clinical signs (probing depth and bleeding on probing) and in the antibacterial effect the LS-007 group showed significant superiority to the PL group. 3. The LS-007 was significantly superior to the PL in decreasing isolated bacterial species. Also, the LS-007 group showed a significant reduction in a number of isolated bacteria, number of blackpigmented Bacteroides spp., and the proportion of black-pigmented Bacteroids spp. in the total isolated bacteria. 4. Noted as side effect was subjective irritation at drug injection in one tooth each of the two groups. From the results it was concluded that LS-007 was a useful drug for the local treatment of periodontitis. Key words: Periodontitis, Local antibiotic therapy, Minocycline HCl, LS-00-, LS-007 ointment base
3
4 melaninogenicus, Haemophilus actinomycetemcomitans,
5
6
7
8
9
10
11
12
13
14
15 5) Walter, C. B., Ratliff, D., Muller, D., Mandell, R. and Socransky, S. S.: Medium for selective isolation of Fusobacterium nucleatum from hu- periodontal pockets. man J. Clin. Microbiol., 10: , ) Slots, J.: Selective medium for isolation of Actinobacillus actinomycetemcomitans. J. Clin. Microbiol., 15: , 1982.
16 7) Mishimo, P. A., Yamamoto, Y., Nakamura, M. periodontal disease: Virulence factors in colonization, and Slot, J.: Selective recovery of oral Capnocytophaga survival, and tissue destruction. J. spp. with sheep blood agar containing Dent. Res., 63: , bacitracin and polimyxin B. J. Clin. Microbiol., 18) Slots, J.: Importance of black-pigmented Bacteroides 17: , in human periodontal disease, Genco, R. J. and Mergenhagen, S. E. Eds., Host-Parasite Interactions in Periodontal Diseases, Amer- ican Society for Microbiology, Washington, D. C., 1982, ) Zambon, J. J., Christersson, L. A. and Slots, J.: Actinobacillus actinomycetemcomitans in human periodontal disease. Prevalence in patient groups and distribution of biotypes and serotypes within families. J. Periodontol., 54: , ) Newman, M. G. and Socransky, S. S.: Predominant cultivable microbiota in periodontosis. J. Periodont. Res., 12: , ) Loesche, W. J., Syed, S. A., Laughon, B. G. and Stoll, J.: The bacteriology of acute necrotizing ulcerative gingivitis. J. Periodontol., 53: ) Ciancio, S. G., Slots, J., Reynolds, H. S., Zambon, 230, J. J. and McKenna, J. D.: The effect of shortterm 22) Tanner, A. C. R., Haffer, C., Bratthall, G. T., administration of minocycline HCl on gin- Visconti, R. A. and Socransky, S. S.: A study of gival inflammation and subgingival microflora. the bacteria associated with advancing periodontitis J. Periodontol., 53: , in man. J. Clin. Periodontol., 6: ) Ciancio, S. G., Mather, M. L., and McMullen, 307, J. A.: An evaluation of minocycline in patients 23) Mashimo, P. A., Yamamoto, Y., Slots, J., Park, with periodontal disease. J. Periodontol., 51: B. H. and Genco, R. J.: The periodontal microflora , of juvenile diabetics : Culture, immuno- 14) Listgarten, M. A., Lindhe, J. and Hellden, L.: fluorescence and serum antibody studies. J. Effect of tetracycline and/or scaling on human Periodontol., 54: , periodontal disease. J. Clin. Periodontol., 5: 24) Savit, E. D. and Socransky, S. S.: Distribution , of certain subgingival microbial species in 15) Lindhe, J., Heul, L., Goodson, J. M. and selected periodontal conditions. J. Periodont. Socransky, S. S.: Local tetracycline delivery Res., 19: , using hollow fiber devices in periodntal therapy. J. Clin. Periodontol., 6: , ) Slots, J.: Subgingival microflora and periodontal disease. J. Clin. Periodontol., 6: , 26) Wolff, L. F., Bakdash, M. B. and Bandt, C. L.: Microbial interpretation of plaque relative to 17) Slots, J. and Genco, R. J.: Black-pigmented the diagnosis and treatment of periodontal Bacteroides species, Capnocytophaga species, and disease. J. Periodontol., 56: , Actinobacillus actinomycetemcomitans in human 27) Slots, J.: The predominant cultivable organ-
17 isms in juvenile periodontitis. Scand. J. Dent. Res., 84: 1-10, ) Slots, J.: The predominant cultivable microflora of advanced periodontitis. Scand. J. Dent.
The positive correlation between bad breath and subgigival microflora OTakafumi Department of Periodontics, Tokyo Dental College MORIYAMA, Masatake TS
A study of ultrasonic scaling with regard to the changes of bacterial phase in the periodontal pocket Department of Periodontology, *Preventive Dentistry, **Bacteriology, Osaka Dental University Masatoshi
More informationMicroflora in Patients Treated with Fixed Prosthetic Appliances Supragingival Plaque Formed on the Full Cast Crown - Fabricated with Platinum Gold Cas
Microflora in Patients Treated with Fixed Prosthetic Appliances Supragingival Plaque Formed on the Full Cast Crown - Fabricated with Platinum Gold Cast Alloy- Junichi Mega, Yosizumi Murata, Masatomo Hirasawa*
More informationHisao Takayasu Department of Urology, Faculty of Medicine, University of Tokyo Masaaki Ohkoshi Department of Urology, Tokai University School of Medic
COMPARATIVE CLINICAL EFFECT OF AMIKACIN AND GENTAMICIN ON COMPLICATED URINARY TRACT INFECTIONS BY DOUBLE-BLIND METHOD Tsuneo Nishiura and Yukimichi Kawada Department of Urology, Gifu University School
More informationCHEMOTHERAPY JUNE 1986
VOL. 34 S-3 CHEMOTHERAPY Fig. 1 Structural formula of L-105 CHEMOTHERAPY JUNE 1986 VOL. 34 S-3 CHEMOTHERAPY Table 1 Antibacterial spectra of L-105 against gram negative anaerobic rods Inoculum 106 cells/ml
More informationCHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study
CHEMOTHERAPY JUNE 1993 Table 1. Background of patients in pharmacokinetic study VOL. 41 S 1 Table 2. Levels (Đg/ml or Đg/g) of S-1006 in serum, bile, and tissue (gallbladder) after oral administration
More information1272 CHEMOTHERAPY MAR. 1975
1272 CHEMOTHERAPY MAR. 1975 VOL. 23 NO. 3 CHEMOTHERAPY 1273 Fig. 2 Minimal inhibitory concentration of aminoglycosides against 50 strains of Klebsiella Fig. 1 Minimal inhibitory concentration of aminoglycosides
More informationFig. 1 Chemical structure of DL-8280
Fig. 1 Chemical structure of DL-8280 Fig. 2 Susceptibility of cl in ical isolates to DL4280 Fig. 5 Susceptibility of clinical isolates to DL-8280 Fig. 3 Susceptibility of clinical isolates to DL-8280 Fig.
More informationClostridium difficile ciprofloxacin, ofloxacin, norfloxacin Bifidobacterium Lactobacillus Lactobacillus Bacteroides fragilis B. fragilis C. difficile
Clostridium difficile ciprofloxacin, ofloxacin, norfloxacin Bifidobacterium Lactobacillus Lactobacillus Bacteroides fragilis B. fragilis C. difficile Key words: temafloxacin, TA-167, Bacteroides fragilis,
More informationVOL.42 S-1
CHEMOTHERAPY APR. 1994 VOL.42 S-1 CHEMOTHERAPY APR. 1994 Table 1. Criteria for evaluation of clinical efficacy by the Japanese Society of Oral and Maxillo-Facial Surgeons Grades of symptoms and numerical
More informationCHEMOTHERAPY Silver sulfadiazine (T 107) CHEMOTHERAPY Fig. 1 Item of patients Table 1 Criteria of bacteriological efficacy by the Committee xcellent: E Score of infection becomes to 0% at the end of medication.
More informationTable 1 Antibacterial spectra of CPM and other antimicrobials against anaerobes Fig. 1 In vitro activity of CPM and other antibiotics against B. fragilis (136 strains) Fig. 2 In vitro activity of CPM and
More information988 CHEMOTHERAPY NOV. 1971
988 CHEMOTHERAPY NOV. 1971 VOL. 19 NO. 8 CHEMOTHERAPY 989 Effect of medium-ph and inoculum size on activity of SB-PC heart infusion agar, mcg/ml Sensitivity distribution of Staphylococci to SB-PC in surgical
More informationTable1MIC of BAY o 9867 against standard strains
Table1MIC of BAY o 9867 against standard strains Fig.2Cumulative and Distribution Curves of MIC (S.aureus 54 strains) 106cfu/ml Fig.3Correlogram of MIC (S.aureus 54 strains) CHEMOTHERAPY 451 Fig.4Cumulative
More informationFig. 1 Chemical structure of KW-1070
Fig. 1 Chemical structure of KW-1070 Fig. 2 Sensitivity distribution of clinical isolates Fig. 4 Sensitivity distribution of clinical isolates Fig. 3 Sensitivity distribution of clinical isolates Fig.
More informationCHEMOTHERAPY Fig. 1 Chemical structure of CXM-AX
Fig. 1 Chemical structure of CXM-AX NOV. 1986 Fig. 2 Sensitivity distribution of clinical isolates organisms (106 cells/ml) a Smurcus 27 strains d) P.m irabilis 15 strains b Ecol i 27 strains 111.morganii
More information1) University Group Diabetes Program: A study of hypoglycemic agents on vascular complica- in patients with adult-onset tions diabetes. I. Design, methods and baseline results. Diabetes 19 (suppl. 2):
More informationCHEMOTHERAPY
CHEMOTHERAPY VOL.41 S-2 Laboratory and clinical evaluation of teicoplanin CHEMOTHERAPY AUG. 1993 VOL.41 S-2 Laboratory and clinical evaluation of teicoplanin Table 1. Comparative in vitro activity of teicoplanin
More informationOsamu NEMOTO, M.D. Clinical and Bacteriological Research of Sucrose/ Povidone-Iodine Ointment (U-PASTA kowa) for Pressure Sores and Skin Ulcers Osamu Nemoto Department of Dermatology,Tonan Hosptal
More information名称未設定-1
Study on Clinical Factors Affecting the Fungal Culture Test - Relevance of Dry Mouth - Yoshiko YAMAMURA, Yukihiro MOMOTA, Hideyuki TAKANO, Koichi KANI, Katsumi MOTEGI, Fumihiro MATSUMOTO, Masayuki AZUMA
More informationThe nursing practices nurses consider important in the tertiary emergency rooms Kanako Honda'', Chizuko Miyake'', Midori Yao", Mikiko Kurushima", Kumiko Toyoda4 "The University of Shiga Prefecture, "Osaka
More informationCHEMOTHERAPY MAY. 1988
CHEMOTHERAPY MAY. 1988 CHEMOTHERAPY Fig. 1 Chemical structure CHEMOTHERAPY MAY. 1988 VOL.36 5-1 CHEMOTHERAPY CHEMOTHERAPY MAY. 1988 VOL.36 S-1 CHEMOTHERAPY CHEMOTHERAPY MAY. 1988 VOL.36 S-1 CHEMOTHERAPY
More informationKey words : R-plasmid, Urinary tract infection, E. coli Fig. 1. MIC distribution against E. coli isolated from urinary tract (366 strains) and isolation - frequencies of drug-resistant strains Table 1.
More informationA Study on Life-Table based on the Death Rate from a Specific Disease by Fumio Nakamura, M. D. Department of Hygiene Okayama University Medical School (Director: Professor Masahiko O. D., M. P. H.) In
More informationFig. 1 Chemical structure of TE-031 Code number: TE-031 Chemical name: (-) (3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-4-[(2, 6-dideoxy-3-C-methyl-3-
Fig. 1 Chemical structure of TE-031 Code number: TE-031 Chemical name: (-) (3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-4-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl) oxy]-14-ethyl-12,
More informationTherapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic c
Therapy for Asthenopia in Cases of Convergence Insufficiency Hiroko TAKASAKI, C.O.J., Nobuko INAGAMI, C.O.J., and Kayoko TAKENAWA, C.O.J.. Orthoptic clinic, Department of Ophthalmology, (Director: Prof
More informationCHEMOTHERAPY DEC Table 1 Antibacterial spectra of T-1982, CTT, CMZ, CTX, CPZ and CEZ 106 CFU/ml Note: P; Peptococcus, S; Streptococcus, G; Gaffk
VOL. 30 S-3 CHEMOTHERAPY imeumoniae, Serratia marcescens, Proteus sp, CHEMOTHERAPY DEC. 1982 Table 1 Antibacterial spectra of T-1982, CTT, CMZ, CTX, CPZ and CEZ 106 CFU/ml Note: P; Peptococcus, S; Streptococcus,
More informationKey words : 7432-S, Oral cephem, Urinary tract infection Fig. 1. Chemical structure of 7432-S.
Key words : 7432-S, Oral cephem, Urinary tract infection Fig. 1. Chemical structure of 7432-S. Table 1. Clinical summary of acute uncomplicated cystitis patients treated with 7432-S UTI : Criteria by the
More informationA ctino bacillus actinomycetemcomitans, Porphyromonas gingivalis, Fusobacterium nucleatum Influence of Complement and Antibody on Superoxide Productio
A ctino bacillus actinomycetemcomitans, Porphyromonas gingivalis, Fusobacterium nucleatum Influence of Complement and Antibody on Superoxide Production, Actinobacillus actinomycetemcomitans, Porphyromonas
More informationFig.2. Sensitivity distribution of clinical isolates of S. epidermidis (24 strains, 106 CFU/ml) Staphylococcus aureus Staphylococcus epider- midis Ent
Fig.2. Sensitivity distribution of clinical isolates of S. epidermidis (24 strains, 106 CFU/ml) Staphylococcus aureus Staphylococcus epider- midis Enterococcus faecalis Klebsiella pneumoniae, Morganella
More informationModulation of T-cell Subsets by Bacteroides gingivalis Department of Periodontics & Endodontics, Faculty of Dentistry, Kyushu University Yuji KITAMURA
Lymphocyte Subsets in mice treated with the fimbriae from Porphyromonas gingivalis Division of Animal Experimentation, Sapporo Medical College,*Department of Preventive Dentistry, Higashi Nippon Gakuen
More informationVOL.35 S-2 CHEMOTHERAPY Table 1 Sex and age distribution Table 2 Applications of treatment with carumonam Table 3 Concentration of carumonam in human
CHEMOTHERAPY Fig. 1 Chemical structure of carumonam Disodium(+)-(Z)-CCE1-(2-amino-4-thiazoly1)-2-[[(2S, -(carbamoyloxymethyl)-4-oxo-1-sulfonato-3-azetidinyll -2-oxoethylidene] amino] oxy] acetate 3S)-2
More informationTable 1.Distribution and number of cases with acute upper respiratory tract infections classified according to antimicrobial agents administered Table 2. Distribution of cases which were enrolled to set
More informationCHEMOTHERAPY APRIL 1992 Table 2. Concentration of meropenem in human prostatic fluid Table 1. Background of 21 chronic complicated UTI cases * NB + BPH, NB + Kidney tumor, NB + Kidney tuberculosis Table
More informationEVALUATION OF NOCTURNAL PENILE TUMESCENCE (NPT) IN THE DIFFERENTIAL DIAGNOSIS OF IMPOTENCE Masaharu Aoki, Yoshiaki Kumamoto, Kazutomi Mohri and Kazunori Ohno Department of Urology, Sapporo Medical College
More informationTitle 歯性病巣の関連する皮膚疾患におけるビオチンの効用 Author(s) 高橋, 愼一 ; 川島, 淳子 ; 森本, 光明 ; 山根, 源之 Journal, (): - URL Right Posted at the Inst
Title 歯性病巣の関連する皮膚疾患におけるビオチンの効用 Author(s) 高橋, 愼一 ; 川島, 淳子 ; 森本, 光明 ; 山根, 源之 Journal, (): - URL http://hdl.handle.net/10130/526 Right Posted at the Institutional Resources for Unique Colle Available from
More informationCHEMOTHERAPY aureus 0.10, Enterococcus faecalis 3.13, Escherichia coli 0.20, Klebsiella pneumoniae, Enterobacter spp., Serratia marcescens 0.78, Prote
aureus 0.10, Enterococcus faecalis 3.13, Escherichia coli 0.20, Klebsiella pneumoniae, Enterobacter spp., Serratia marcescens 0.78, Proteus mirabilis 3.13, Proteus vulgaris 1.56, Citrobacter freundii 0.39,
More information*...C
J Health Care Dent. 2004; 6: 23-41 Printed in Japan. All rights reserved * Reconsideration of Diagnosis, Treatment and Maintenance of Periodontal Disease Periodontitis is different from other infectious
More informationEffects of Light and Soil Moisture Condition on the Growth of Seedlings for Quercus serrata and Quercus variabilis NISHIMURA, Naoyuki*, OTA, Takeshi**
Effects of Light and Soil Moisture Condition on the Growth of Seedlings for Quercus serrata and Quercus variabilis NISHIMURA, Naoyuki*, OTA, Takeshi**, SAKAMOTO, Keiji*** and CHIBA, Kyozo*** Key words:
More informationCHEMOTHERAPY APRIL 1992 VOL. 40 S- 1 Table 1-1. Comparative in vitro activity of meropenem against clinical isolates CNS: coagulase-negative staphylococci CHEMOTHERAPY APRIL 1992 Table 1-2. Comparative
More informationThe Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursi
The Journal of the Japan Academy of Nursing Administration and Policies Vol 7, No 2, pp 19 _ 30, 2004 Survey on Counseling Services Performed by Nursing Professionals for Diabetic Outpatients Not Using
More informationCHEMOTHERAPY JUN Citrobacter freundii 27, Enterobacter aerogenes 26, Enterobacter cloacae 27, Proteus rettgeri 7, Proteus inconstans 20, Proteus
VOL. 32 S-4 CHEMOTHERAPY Fig. 1 Chemical structure of sodium cefoperazone Fig. 2 Chemical structure of sodium cefoperazone CHEMOTHERAPY JUN. 1984 Citrobacter freundii 27, Enterobacter aerogenes 26, Enterobacter
More informationKey words : candidemia, endotoxin, D-arabinitol, Candida antigen, serological examination
Key words : candidemia, endotoxin, D-arabinitol, Candida antigen, serological examination Fig. 1 The value of fungal index and D- arabinitol/creatinine. Fungal index was mesured by Endotoxin D and Endospecy
More informationsemen quality or those without WBC in semen. In the patients with azoospermia and normal FSH levels (normogonadotropic azzospermia), the antibody (IgG
CLINICAL STUDIES OF UROGENITAL INFECTIONS WITH CHLAMYDIA TRACHOMA TIS Report 2. The Epidemiology of Chlamydial Infections in Okayama District in Japan and Detection of Antibodies to Chlamydiae in the Sera
More informationChanges in Electrodermal Activity Associated with Candies and Chewing Gum Chewing Satoshi Beppu, Takeshi Morita*, Susumu Igarashi **, Kanichi Seto* an
Changes in Electrodermal Activity Associated with Candies and Chewing Gum Chewing Satoshi Beppu, Takeshi Morita*, Susumu Igarashi **, Kanichi Seto* and Yosihiro Amemiya Abstract: This study was designed
More informationClinical Factors which Affect the Shortend Life Span of Abutment Teeth in Removable Partial Denture Mitsuhiro Yoshida Abstract: In order to establish diagnostic parameters for the estimation of prognosis
More informationFig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution of female patients with blad
Key words: Female with bladder irritability, Subjective symptoms, Pyuria, Bacteriuria Fig. 1 Clinical findings and extent of inflammation area in female urethrocystitis Fig. 2 Classification and distribution
More informationTable 1 Survival rates of infected mice given antibiotic doses producing peak serum a) S. aurcus Smith Challenge dose :7 ~10 (5% mucin) CFU/mouse. LD50: 1 ~103 (5% mucin) CFU/mouse. Table 2 Survival rates
More information日本化学療法学会雑誌第53巻第S-3号
moxifloxacin in vitro moxifloxacin in vitro 17 9 6 17 11 21 moxifloxacinmflx in vitro cefdinir CFDNclavulanic acidamoxicillincvaampcclarithromycincamclindamycincldm levofloxacinlvfx 1MFLX Clostridium clostridiiformeclostridium
More informationVOL. 40 S- 1 Table 1. Susceptibility of methicillin-resistant Staphylococcus aureus to meropenem Table 2. Coagulase typing of methicillin-resistant St
CHEMOTHERAPY VOL. 40 S- 1 Table 1. Susceptibility of methicillin-resistant Staphylococcus aureus to meropenem Table 2. Coagulase typing of methicillin-resistant Staphylococcus aureus CHEMOTHERAPY Table
More informationFig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamin
Fig. 1 A: Effects of intramuscular injection of glucagon on the blood glucose levels (changes from basal, ƒ BG) as compared with effects of scopolamine butylbromide during upper gastrointestinal endoscopy.
More informationTable 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates
Table 1. Antibacterial activitiy of grepafloxacin and other antibiotics against clinical isolates Table 2-1. Summary of patients treated with grepafloxacin for respiratory infection 1) Out: outpatient,
More informationVOL. 23 NO. 3 CHEMOTHERAPY 1067 Table 2 Sensitivity of gram positive cocci isolated from various diagnostic materials Table 3 Sensitivity of gram nega
1066 CHEMOTHERAPY MAR. 1975 Table 1 Sensitivity of standard strains VOL. 23 NO. 3 CHEMOTHERAPY 1067 Table 2 Sensitivity of gram positive cocci isolated from various diagnostic materials Table 3 Sensitivity
More informationVOL. 17 NO. 7 CHEMOTHERAPY 1305 1) W. BRumFirr et al. : Clinical and laboratory studies with carbenicillin. Lancet 1: 1289~ 1293, 1967 2) E. T. KNUDSEN et al. : A new semisynthetic penicillin active against
More informationCHEMOTHERAPY AUG. 1982 VOL. 30 NO. 8 CHEMOTHERAPY Fig.1 Relation between various-closis of cefazolin and detection rate of organisms in heart blood of dying mice with E. coli and P. aeruginosa infection
More informationThe Japanese Journal of Health Psychology, 29(S): (2017)
Journal of Health Psychology Research 2017, Vol. 29, Special issue, 139 149Journal of Health Psychology Research 2016, J-STAGE Vol. Advance 29, Special publication issue, 139 149 date : 5 December, 2016
More informationDISTRIBUTION OF NEUROPEPTIDES IN THE INFERIOR NASAL TURBINATE MUCOSA OF PATIENTS WITH ALLERGIC RHINITIS KAZUHIRO YAMAMOTO. M.D. Department of Otolaryngology, School of Medicine, Kitasato University, Sagamihara
More informationA sensory testing of mental nerve by Semmes-Weinstein monofilaments standard value from 19 -A to 29 years old- The objective of the present study was
A sensory testing of mental nerve by Semmes-Weinstein monofilaments standard value from 19 -A to 29 years old- The objective of the present study was to investigate the distribution of static tactile thresholds
More information_念3)医療2009_夏.indd
Evaluation of the Social Benefits of the Regional Medical System Based on Land Price Information -A Hedonic Valuation of the Sense of Relief Provided by Health Care Facilities- Takuma Sugahara Ph.D. Abstract
More informationA Clinical Study on Dental CAD/CAM CEREC(R) System Fitness of CEREC(R) Porcelain Laminate Veneers-- Takashi Nakamura, Yutaka Tanaka*, Hiroyuki Ogawa,
A Clinical Study on Dental CAD/CAM CEREC(R) System Fitness of CEREC(R) Porcelain Laminate Veneers-- Takashi Nakamura, Yutaka Tanaka*, Hiroyuki Ogawa, Takeshi Akao, Aogu Imanishi, Toshizumi Hino and Takao
More informationTable 1.Concentration of gatifloxacin (Middle-ear) Table 2.Concentration of gatifloxacin (Paranasal sinuses) Table 3.Concentration of gatifloxacin (Tonsil) Table 4.No.of patients studied Table 5.Background
More information* * 2
* * Study on Fire Resistance of Reinforced Concrete Columns with Ultra High Strength Material Munehiro UMEMOTO * Shigemi KIKUTA * The reinforced concrete column made with the high-strength concrete has
More informationCHEMOTHERAPY FEB Table 1. Activity of cefpirome and others against clinical isolates
VOL.39 S-1 CHEMOTHERAPY FEB. 1981 Table 1. Activity of cefpirome and others against clinical isolates VOL.39 S-1 CHEMOTHERAPY FEB. 1991 72 M, 55.5 kg 66 F, 53 kg Chronic bronchitis Bronchopneumonia Peak
More informationA Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, Sc
A Nutritional Study of Anemia in Pregnancy Hematologic Characteristics in Pregnancy (Part 1) Keizo Shiraki, Fumiko Hisaoka Department of Nutrition, School of Medicine, Tokushima University, Tokushima Fetal
More informationCHEMOTHERAPY APR Fig. 2 The inactivation of aminoglycoside antibiotics by PC-904 Fig. 3 Serum concentration of PC-904 (1) Fig. 4 Urinary recover
VOL.26 S-2 CHEMOTHERAPY Gentamicin (GM), Dibekacin (DKB), Tobramycin Fig. 1 Protein concentration and protein binding rate Table 2 Protein binding rate of PC-904 in serum of healthy adults, and patients
More informationWeb Stamps 96 KJ Stamps Web Vol 8, No 1, 2004
The Journal of the Japan Academy of Nursing Administration and Policies Vol 8, No 1, pp 43 _ 57, 2004 The Literature Review of the Japanese Nurses Job Satisfaction Research Which the Stamps-Ozaki Scale
More informationJJRM5005/04.短報.責了.indd
Jpn J Rehabil Med 2013 ; : 319.327 1 2 3 4 5 6 Survey of the Electronic Medical Recoding System Used in Kaifukuki Rehabilitation Wards Hidekazu SUGAWARA, 1 Tetsutaro YAHATA, 2 Hideto OKAZAKI, 3 Mitsuhiro
More informationVOL. 21 NO. 2 CHEMOTHERAPY 395
394 CHEMOTHERAPY MAR. 1973 VOL. 21 NO. 2 CHEMOTHERAPY 395 396 CHEMOTHERAPY MAR. 1973 VOL. 21 NO. 2 CHEMOTHERAPY 397 398 CHEMOTHERAPY MAR. 1973 VOL. 2 1 NO. 2 CHEMOTHERAPY 399 400 CHEMOTHERAPY MAR. 1973
More informationVisual Evaluation of Polka-dot Patterns Yoojin LEE and Nobuko NARUSE * Granduate School of Bunka Women's University, and * Faculty of Fashion Science,
Visual Evaluation of Polka-dot Patterns Yoojin LEE and Nobuko NARUSE * Granduate School of Bunka Women's University, and * Faculty of Fashion Science, Bunka Women's University, Shibuya-ku, Tokyo 151-8523
More informationA comparison of abdominal versus vaginal hysterectomy for leiomyoma and adenomyosis Kenji ARAHORI, Hisasi KATAYAMA, Suminori NIOKA Department of Obstetrics and Gnecology, National Maizuru Hospital,Kyoto,
More informationcoccus aureus Corynebacterium sp, Haemophilus parainfluenzae Klebsiella pneumoniae Pseudornonas aeruginosa Pseudomonas sp., Xanthomonas maltophilia, F
VOL.43 S-1 coccus aureus Corynebacterium sp, Haemophilus parainfluenzae Klebsiella pneumoniae Pseudornonas aeruginosa Pseudomonas sp., Xanthomonas maltophilia, Flavobacter- Table 1. Concentration of grepafloxacin
More informationVOL. 34 S-2 CHEMOTH8RAPY 913
VOL. 34 S-2 CHEMOTH8RAPY 913 914 CHEMOTHERAPY APR. 1986 Fig. 1 Chemical structure of T-2588 and T-2525 T- 2588 pivaloyloxymethyl (+ )- (6 R, 7 R)-7-[(Z)-2- (2-amino- 4-thiazolyl)-2-methox yiminoacetamido]-3-[(
More informationStudies of Foot Form for Footwear Design (Part 9) : Characteristics of the Foot Form of Young and Elder Women Based on their Sizes of Ball Joint Girth
Studies of Foot Form for Footwear Design (Part 9) : Characteristics of the Foot Form of Young and Elder Women Based on their Sizes of Ball Joint Girth and Foot Breadth Akiko Yamamoto Fukuoka Women's University,
More informationDo probiotic bacteria improve human oral microbiota? NOBUKO MAEDA, TOMOKO OHSHIMA, KENICHI HOJO and NAOKI TAKETOMO The term eprobiotics f is defined a
Do probiotic bacteria improve human oral microbiota? NOBUKO MAEDA, TOMOKO OHSHIMA, KENICHI HOJO and NAOKI TAKETOMO The term eprobiotics f is defined as eliving microorganisms that exhibit beneficial effects
More informationCHEMOTHERAPY Table 1 Clinical effect of Sultamicillin
CHEMOTHERAPY CHEMOTHERAPY Table 1 Clinical effect of Sultamicillin CHEMOTHERAPY Fig. 1 MICs of sultamicillin against respiratory pathogenic Branhamella catarrhalis 62 strains, inoculum size 106CFU/m1 Fig.
More informationⅡ. 用語の操作的定義 Ⅲ. 対象と方法 1. 対象 WAM NET 2. 調査期間 : 3. 調査方法 4. 調査内容 5. 分析方法 FisherMann-Whitney U Kruskal-Wallis SPSS. for Windows 6. 倫理的配慮 Vol. No.
研究報告 The Relation Between the Manager s Administrative Abilities Including Business Activities in Visiting Nursing Stations and the Station s Financial Profits Chisato Fujii Akiko Akama Mariko Ohtake Ikuko
More information明海大学歯学雑誌 37‐2/1.秦泉寺
J Meikai Dent Med 37, 153 158, 8 153 1 7 5ml /1 min Wong-Baker Face Rating Scale FS 5 1 9. g 3 5ml /1 min, FS 1 66 6ml /1 min FS 5 1 9. g 3 6ml /1 min, FS 3 Two Cases of Xerostomia that Showed an Improvement
More informationUnknown
Journal of Breast and Thyroid Sonology Journal of Breast and Thyroid Sonology Vol.2, No.3 July 2013 Report The 30 th Meeting of Japan Association of Breast and Thyroid Sonology... 1 Department of Organ
More informationVOL.30 NO.10 CHEMOTHERAPY 1123 Fig,1 Group B case 6 hepatolithiasis,e.k.66 y.0.,f.45kg Postoperative wound infection Fig.2 Group B case 15 gastric cancer,k.k.60 y.o.,m. Postoperative peritonitis Fig.3
More information2) Goetz, A., Tsuneishi, N.: Application of molecular filter membranes to the bacteriological analysis of water, J. Am. Water Works Assn., 43 (12): 943-969,1951. 3) Clark, H.F. et al.: The membrane filter
More informationCHEMOTHERAPY JAN Fig. 1 Structure of cephradine
VOL. 23 NO. 1 CHEMOTHERAPY 409 CHEMOTHERAPY JAN. 1975 Fig. 1 Structure of cephradine VOL. 23 NO. 1 CHEMOTHERAPY 411 Table 1 Reason for drop-out 412 CHEMOTHERAPY JAN. 1975 VOl. 23 NO. 1 CHEMOTHERAPY 413
More informationFig.1 MICs of penicillins against 24 strains of B. pertussis Fig.2 MICs of cepherns against 24 strains of B. pertussis Fig.3 MICs of macrolides against 24 strains of B. pertussis Fig.4 MICs of nalidixic
More informationTakeji NISHIKAWA, M. D.*, Takashi HARADA, M. D.** and Tatsuya IZUML M. D. Toshiyuki SUGI, M. D. Hiroshi HANYAKU, M. D. Shun-ichi MIYAKAWA, M. D. and Masaru TANAKA, M. D. Nobuko INAMOTO, M. D. and Hironori
More informationTitle 神経因性膀胱にともなう排尿障害に対する塩酸ブナゾシンの臨床効果 - 二重盲検比較試験による検討 - 小柳, 知彦 ; 富樫, 正樹 ; 丸, 彰夫 ; 折笠, 精一 ; 相馬, Author(s) 崎, 淳 ; 安田, 耕作 ; 阿曽, 佳郎 ; 本問, 之夫 ; 三宅, 弘厚生 ; 熊
Title 神経因性膀胱にともなう排尿障害に対する塩酸ブナゾシンの臨床効果 - 二重盲検比較試験による検討 - 小柳, 知彦 ; 富樫, 正樹 ; 丸, 彰夫 ; 折笠, 精一 ; 相馬, Author(s) 崎, 淳 ; 安田, 耕作 ; 阿曽, 佳郎 ; 本問, 之夫 ; 三宅, 弘厚生 ; 熊澤, 淨一 ; 武井, 実根雄 Citation 泌尿器科紀要 (1990), 36(10): 1233-1252
More information日本化学療法学会雑誌第65巻第4号
Mycoplasma pneumoniae M. pneumoniae M. pneumoniae M. pneumoniae M. pneumoniae M. pneumoniae Key words Mycoplasma pneumoniae Mycoplasma pneumoniae M. pneumoniae I M. pneumoniae M. pneumoniae M. pneumoniae
More informationKey words: E. coli O 157: H7, fosfomycin, verotoxin, mouse infection
Key words: E. coli O 157: H7, fosfomycin, verotoxin, mouse infection Table 1. Bacterial cell counts in feces of mice infected with Esclwrichia coli O 157: H7 NK2 before and during oral dosing with fosfomycin
More information国土技術政策総合研究所 研究資料
ISSN TECHNICAL NOTE of National Institute for Land and Infrastructure Management No256 September 2005 Experimental Study on Seismic Behavior of Seawalls for Controlled Waste Disposal Shingo KANO, Katsuya
More informationTitle 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date URL
Title 泌尿器科領域に於ける17-Ketosteroidの研究 17-Ketosteroidの臨床的研究 第 III 篇 : 尿 Author(s) 卜部, 敏入 Citation 泌尿器科紀要 (1958), 4(1): 3-31 Issue Date 1958-01 URL http://hdl.handle.net/2433/111559 Right Type Departmental Bulletin
More informationArthroscopic Treatment for Painful Bennett Lesions of the Shoulder in Baseball Players by M. Yoneda and K. Hayashida Department of Orthopaedic Surgery
Arthroscopic Treatment for Painful Bennett Lesions of the Shoulder in Baseball Players by M. Yoneda and K. Hayashida Department of Orthopaedic Surgery, Osaka Kosei-Nenkin Hospital K. Izawa and S. Wakitani
More information1) Michaelis L. Biochem Z., 59, 78, 1914. 2) Ferris H. C. Dent. Cosmos Phila., 63, 10, 93, 1921. 3) Bloomfield A. L. Bull Johns Hopk. Hosp. Bait., 31, 118, 1920. 4) Starr H. C. J. Biol. Chem. Bait., 54,
More informationESTIMATION OF THE SALIVARY ANTIBACTERIAL ACTIVITY IN TRYPTICASE SOY AGAR BY CUP PLATE METHOD BY Hajime TAKAHATA, Toshio MORIOKA and Toshiharu MATSUMURA The peroxidase antibacterial action in human saliva
More information1) Kojima H: Culture of ejaculate for Neisseria gonorrhoeae, 1st Serually Transmitted Diseases World Congress, San Juan, 11. 19, 1981. 9) Kojima H, Mori C: Clinical studies on Conococcal and Chlamydial
More informationEndocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Depa
Endocrinological and statistical analysis of ovarian function in hysterectomized patients Masaya HAYAFUJI, Kazuaki KATAYAMA and Matsuto MOCHIZUKI Department of Obstetrics and Gynecology, Kobe University
More informationStudies on the Antigens Expressed on Trophoblasts Related to MLR-blocking Antibodies Shigenori GOTO Department of Obstetrics and Gynecology, Niigata University School of Medicine (Director: Prof. Shoshichi
More informationI Jpn Prosthodont Soc 47: 779-786, 2003 A Study of Masticatory Ability in the Elderly A Comparison between Dentulous Subjects and Denture - Wearers- Nakashima Mihoko, Okimoto Kimie, Matsuo Koichi and Terada
More information106(18) 原 使 用 した 測 定 部 位 は 期 門 穴相 当部 位 の 表 皮 上 及 び 真 皮 下 と し, 表 皮上 で は 艾 柱 の 直 下 に 熱 電 対 先 端 を露 出 し固 定 した 真 皮 下 で は施 灸部 より10mm 下 方 を切 開 剥 離 し, 施 灸 部 直
106(18) 原 使 用 した 測 定 部 位 は 期 門 穴相 当部 位 の 表 皮 上 及 び 真 皮 下 と し, 表 皮上 で は 艾 柱 の 直 下 に 熱 電 対 先 端 を露 出 し固 定 した 真 皮 下 で は施 灸部 より10mm 下 方 を切 開 剥 離 し, 施 灸 部 直 下 に 熱 電 対 先端 が 届 くよ うに挿 入 した 熱 電 対 の 出 力 は 温 度 モ ジュ
More information日本消化器外科学会雑誌第29巻第9号
Table 1 Oligonucleotide primers used for RT-PCR and internal probes used for Southern blot hybridization Cytokine Primer Sequence (5'-3') 5' 3' Internal probe s' 3' Internal probe 5' 3' Internal probe
More information05_藤田先生_責
This report shows innovation of competency of our faculty of social welfare. The aim of evaluation competency is improvement in the Social welfare education effects, by understanding of studentʼs development
More informationI
九州大学学術情報リポジトリ Kyushu University Institutional Repository 熊本県水俣市の限界集落における耕作放棄地の拡大とその要因 寺床, 幸雄九州大学大学院人文科学府 : 博士後期課程 : 農村 農業地理学 Teratoko, Yukio http://hdl.handle.net/2324/20036 出版情報 : 地理学評論. 82 (6), pp.588-603,
More informationStudy on Application of the cos a Method to Neutron Stress Measurement Toshihiko SASAKI*3 and Yukio HIROSE Department of Materials Science and Enginee
Study on Application of the cos a Method to Neutron Stress Measurement Toshihiko SASAKI*3 and Yukio HIROSE Department of Materials Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa-shi,
More informationTable 1 Sensitivity distribution of clinical isolates 1. Escherichia coli Inoculum size: 106cells/ml 2. Klebsiella pneumoniae 3. Enterobacter cloacae 4. Serratia marcescens Inoculum size: 106cells/nil
More information