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3 Special Issue 1Lifestyle and prevention of diseases during the middle and advanced ages Special Issue 2Treatment of wound and scar up to date Reviews Originals

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11 Lifestyle modification to prevent cardiovascular diseases Masataka Sata Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima Japan

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17 Lifestyle and osteoporosis ; prevention of fragility fracture Hirokazu Uemura, Mineyoshi Hiyoshi, Hideo Takeda, Atsushi Kitayama, Hidenobu Takami, Fusakazu Sawachika, Miwa Yamaguchi, and Kokichi Arisawa Department of Preventive Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

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23 Periodontal disease, as a lifestyle-related disease, and as a risk factor for several other systemic lifestyle-related diseases Hiro-O Ito Department of Preventive Dentistry, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

31 Actual conditions and prophylaxis for disuse syndrome in elderly residents of Tokushima Prefecture considered from the perspective of habits in daily living Shinjiro Takata, and Natsuo Yasui Division of Rehabilitation, Tokushima University Hospital, and Department of Orthopedics, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

34 in vitro in vivo

37 et al et al Is the common knowledge true in wound healing Ichiro Hashimoto, and Hideki Nakanishi Department of Plastic Surgery, Institute of Health Bioscience, the University of Tokushima Graduate School, Tokushima, Japan

40 et al et al et al

41 Prevention of pressure ulcers in home care patients Kazuya Matsumoto,IchiroHashimoto,ShinjiMatsuo, Hideki Nakanishi, Yoshiaki Kubo Kazutoshi Murao, and Seiji Arase Section of Plastic and Reconstructive Surgery, Kitajima Taoka Hospital, Tokushima, Japan ; Department of Plastic and Reconstructive Surgery, and Department of Dermatology, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

44 １４３糖尿病の足病変 A B 図６運動神経障害による典型的な Hammer toe 変形を示す寺師浩人足の創傷をいかに治すか市岡滋寺師浩人編集克誠堂出版東京２００９より引用する図１自律神経障害である A-V shunt 機能不全による皮膚代謝低下を示す寺師浩人足の創傷をいかに治すか市岡滋寺師浩人編集克誠堂出版東京２００９より引用する A 正常足底皮膚 B 糖尿病による自律神経障害による皮膚循環障害図７ Claw toe 変形を示す寺師浩人足の創傷をいかに治すか市岡滋寺師浩人編集克誠堂出版東京２００９より一部引用する A 側面像を示す母趾 MTP 関節離断直後の状態である B その後に２趾背側に靴擦れから潰瘍形成し関節と骨が露出した A B 図２典型的 Charcot 足の急性期を示す潰瘍は誤った切開創である A A B B 図３図２症例の足底潰瘍を示す A 足底中心部に潰瘍がある B 単純 XP では足根骨の破壊像がある A A B 図９母趾 MTP 関節と骨壊死症例を示す寺師浩人足の創傷をいかに治すか市岡滋寺師浩人編集克誠堂出版東京２００９より引用する A 関節面の壊死を示す B デブリードマン直後の状態で腐骨となっている土踏まずから神経付きの内側足底動脈穿通枝皮弁を挙上した C 腐骨もデブリードマンしその上に皮弁を移動させドナーには植皮を施行した図４足底外側の潰瘍症例を示す A 小趾中足骨遠位端部潰瘍である母趾中足 B 骨遠位端部に皮弁による治癒歴を有す B Charcot 膝のため膝関節内側が破壊され下腿の軸が内側に向い C たため足底外側に潰瘍ができたことがわかる図５足底皮膚の組織像を示す HE 染色自律神経障害によるエクリン汗管とエクリン汗腺の機能不全で上皮化障害と亀裂を起こしやすくなる図８歩行時 toe off 時の踏み返しによる中足骨遠位端部の潰瘍を示す A 第２趾と５趾の踏み返し部に潰瘍がある B 母趾の踏み返し部の潰瘍 black heel 形成と第２趾踏み返し部の水疱を示す A B C D 図１０母趾踏み返し部の潰瘍症例を示す A 潰瘍のすぐ深部に骨を触れた B 保存的加療にて治癒後状態を示す胼胝を削っているが皮膚の直下には骨を触れる C 足底に合わせた足底板を示す D 足底板を足に合わせたところを示す

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49 Diabetic foot lesion Hiroto Terashi Department of Plastic and Reconstructive Surgery (Chief : Shinya Tahara), Kobe University Hospital, Hyogo, Japan

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53 et al et al et al Anti-aging cosmetic medicine Kotaro Yoshimura Department of Plastic Surgery, University of Tokyo Graduate School of Medicine, Tokyo, Japan

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55 Effects of rehabilitation makeup (rehabili-make ) on promoting a quality of life of patients with visible disfigurements Reiko Kazuki REIKO KAZKI, and Nippon Medical School, Tokyo, Japan Director : Prof. Hiko Hyakusoku (Nippon Medical School Hospital, Tokyo, Japan)

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63 et al et al Radiation therapy -state of the art and in future- Hitoshi Ikushima Department of Radiation Therapy Technology, Institutes of Health Bioscience, the University of Tokushima Graduate School, Tokushima, Japan

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73 A review of cause of high frequent diabetic mortality in Tokushima Prefecture from existing data and papers Midori Yoshida,andToshikoTada Department of Oral and Maxillofacial Radiology, and Department of Community Nursing, Major in Nursing, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

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77 et al et al et al é et al The establishment of therapy targeting the intestinal transporter genes for chronic kidney disease Hiroko Kikuchi, Hironori Yamamoto, Sarasa Tanaka, Otoki Nakahashi, Shoji Kuwahara, Yoshitaka Nii, Ken-ichi Miyamoto, Yutaka Taketani, and Eiji Takeda Department of Clinical Nutrition, and Department of Molecular Nutrition, Institute of Health Biosciences, the University of Tokushima Graduate School ; and Food Technology Division, Tokushima Prefecture Industrial Technology Center, Tokushima, Japan

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81 et al. Incidence rate of Kawasaki Disease is increasing, still now -surveyforyears in Tokushima Prefecture - Suguru Matsuoka, Kazuhiro Mori, Yasuhito Yuasa, Masahiro Kubo, Tetsuya Yoshida, Tadanori Nakatsu, Takao Ichioka, Tadashi Yamada, Takashi Ueda, Noboru Satou, Miki Inoue, and Yasunobu Hayabuchi Tokushima Meeting for Kawasaki Disease : Tokushima Municipal Hospital ; Tokushima Prefectural Central Hospital ; Tokushima Red Cross Hospital ; Naruto Health Insurance Hospital ; Oe Kyoudou Hospital ; Anan Kyouei Hospital ; Awa Hospital ; and Department of Pediatrics,Tokushima University Hospital, Tokushima, Japan

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87 Clinical study on serum Mg concentration and kidney functions of outpatients to be treated with magnesium oxide Hiroaki Mitani Mitani Clinic, Anan, Tokushima, Japan

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91 et al et al et al et al Adaptiveservo ventilator versus oxygen therapy in patients with heart failure (the effect of adaptiveservo ventilator on right heart failure with pulmonary arterial hypertension) Kana Kondo, Akira Takashima, Shusuke Yagi, Masashi Akaike, Takashi Iwase, Kenya Kusunose, Toshiyuki Niki, Koji Yamaguchi, Kunihiko Koshiba, Yoshio Taketani, Noriko Tomita, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, and Masataka Sata The Postgraduate Education Center, Tokushima University Hospital, and Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan

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118 Special IssueManagement principles in the critically ill - Review Case reports

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120 Special IssueOncology Nutrition Reviews Proceeding

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122 Special Issue 1Lifestyle and prevention of diseases during the middle and advanced ages Special Issue 2Treatment of wound and scar up to date Reviews Originals

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125 Editor-in-Chief Editors Published by Tokushima Medical Association in

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第６２巻５・６号（１２月号）／特集１・巻頭言

第６２巻５・６号（１２月号）／特集１・巻頭言 Special Issue 1Recent advances in radiation diagnosis and radiation therapy Special Issue 2The way and the power for overcoming diabetes mellitus Review Originals Current topics on radiation exposure