放射線ホルミシス太田成男
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- いちえい あみおか
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1 Key words: hormesis horme ( to excite) Radiation hormesis 1978 D 20! T.D. ( ), ( ) : (2011/08) 1,000 msv 3, (Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII-Phase 2 BEIR ( 2005)) adaptive response ionizing irradiation 70% H 2 0 OH H e- OH OH 20
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6 (6) radioadaptive response adaptive response (1) Ristow M, Zarse K: How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp Gerontol 45, , 2010 (2) Qian L, Cao F, Cui J, Wang Y, Huang Y, Chuai Y, Zaho L, Jiang H, Cai J: The potential cardioprotective effects of hydrogen in irradiated mice. J. Radial Res 51, , 2010 (3) Mifune M, Sobue T, Arimoto H, Komoto Y, Kondo S, Tanooka H: Cancer mortality survey in a spa area (Misasa, Japan) with a high radon background. Jpn J Cancer Res 83, 1-5, 1992 (4) Cohen BL: Test of the linear-no threshold theory of radiation carcinogenesis for inhaled radon decay products. Health Phys 68, , 1995 (5) Chen WL, Luan YC, Shieh MC, Chen ST, Kung HT, Soong KL, Yeh YC, Chou TS, Mong SH, Wu JT, Sun CP, Deng WP, Wu MF, Shen ML: Effects of cobalt-60 exposure on health of Taiwan residents suggest new approach needed in radiation protection. Dose Response 5, 63-75, 2006 (6) Hwang SL, Hwang JS, Yang YT, Hsieh WA, Chang TC, Guo HR, Tsai MH, Tang JL, Lin IF, Chang WP: Estimates of relative risks for cancers in a population after prolonged low-dose-rate radiation exposure: a follow-up assessment from 1983 to Radiat Res 170, , 2008 (7) Caratero A, Courtade M, Bonnet L, Planel H, Caratero C: Effect of a continuous gamma irradiation at a very low dose on the life span of mice. Gerontology 44, , 1998 (8) Ina Y, Sakai K: Prolongation of life span associated with immunological modification by chronic low-dose-rate irradiation in MRL-lpr/lpr mice. Radiat Res 161, , 2004
7 (9) Tanaka S, Tanaka IB 3rd, Sasagawa S, Ichinohe K, Takabatake T, Matsushita S, Matsumoto T, Otsu H, Sato F: No lengthening of life span in mice continuously exposed to gamma rays at very low dose rates. Radiat Res 160, , 2003 (10) Moskalev AA, Plyusnina EN, Shaposhnikov MV: Radiation hormesis and radioadaptive response in Drosophila melanogaster flies with different genetic backgrounds: the role of cellular stress-resistance mechanisms. Biogerontology 12, , 2011
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