3M TM Chlorhexidine Gluconate IV Securement Dressings Tegaderm TM CHG Support CRBSI Prevention
TegadermTM CHG Dressing 2w/w% 60% N. Safdar, Intensive Care Med 2004 30 62-7
Guideline Centers for Disease Control and Prevention CDC Healthcare Infection Control Practice Advisory Committee HICPAC, Guideline for the Prevention of Intravascular Catheter-Related Infections 2011, 33 2012, 111-113,
7 days 5 10mm Mean Log Count log(10)cfu/cm 2 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0.0 31 31 31 30 30 30 30 M.H.BashirAmerican Journal of Infection Control 2012 40 344-348 Zone of Inhibition Beyond Gel Pad(MM) 12.0 10.0 8.0 6.0 4.0 2.0 0.0 1 2 3 4 5 6 7 8 9 10 Days Debra L SchwabInfusion Nurses Society INS 2008 5 in Vitro test w/w% 0% 100% 200% Change
GRAM POSITIVE ZOI GRAM NEGATIVE & YEAST ZOI AVERAGE ZONE GEL DIAMETER 24 MM faecalis Wound Isolate #23 faecalis 19433 faecalis 7080 faecium(mdr)51559 faecium(vre)700221 Corynebacterium diphtheriae 13812 aureus Nasal Isolate #849 aureus (MRSA)USA 800 aureus (MRSA)USA 500 aureus (MRSA)USA 600 epidermidis 1228 60 50 40 30 20 10 epidermidis 13518 epidermidis 49461 epidermidis 49134 epidermidis 14990 epidermidis(mrse) 51625 epidermidis(mrse) nasal isolate #492 aureus 25923 aureus (MRSA/GRSA)33592 aureus (MRSA)USA 100 aureus (MRSA)USA 300 AVERAGE ZONE Acinetobacter baumannii GEL DIAMETER 19606 24 MM Candida albicans 40 58716 Candida albicans 30 10231 20 Proteus mirabilis 7002 10 Proteus mirabilis 12453 Escherichia coli 25922 Klebsiella pneumoniae 23357 Klebsiella pneumoniae 13883 Enterobacter cloacae 35549 Acinetobacter baumannii BAA-747 Acinetobacter baumannii BAA-747 Pseudomonas aeruginosa 10145 Pseudomonas aeruginosa 10662 Pseudomonas aeruginosa 35032 Pseudomonas aeruginosa 9027 Pseudomonas aeruginosa 27853 J. P. Hensler Europian Congress of Clinical Microbiology and Infectious Diseases ECCMID Effective Against Most Common Pathogens Causing CRBSIs
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