30% 20% 24 (quality of life;qol) QOL '79 '89 '02 (Sleep apnea syndrome;sas) 1
SAS 2
5 P 5 P ( 1) (Physical) (Physiological) (Psychological) (Psychiatric) (Pharmacological) SAS 3
( ) 5 ( ) 4
( ) ( ) ( ) SAS 5
Charles Dikens ( 1) Burwell '56 Pickwick '76 Guilleminault SAS 10 30 10 1 5 (,apnea index;ai 5) '90 (ICSD) 2 (Central SAS;CSAS) (Obstructive SAS;OSAS) 6
CSAS OSAS '99 (AASM) 1/2 (Central sleep apnea-hypopnea syndrome) CSAHS (Obstructive sleep apnea-hypopnea syndrome) OSAHS 2 OSAHS 7
OSAHS OSAHS OSAHS 1 2 4 0.5 2 2 8 SAS 8
SAS SAS SAS 3 SAS P22 SAS SAS SAS SAS 3 9
SAS SAS 3 5 Maine California SAS 10
SAS 40 70 20 OSAHS SAS SAS 11
SAS SAS a.ess(epworth sleepiness scale 4) 8 6 SAS 12 b. ( 5) WHO (WWPSH) ESS (Polysomnography;PSG) SAS PSG SAS PSG OSAHS ( 12
;AHI) 5 15 15 30 30 PSG PSG OSAHS a. b. ( ) c. MRI SAS a. (Multiple sleep latency test;mslt) PSG 2 4 5 ( ) 13
10 5 SAS MSLT 10 ICSD b. (Maintenance of wakefulness test;mwt) MSLT 14
15
OSAHS 4 5 SAS OSAHS OSAHS 16
n-cpap(nasal continuous positive airway pressure ) n-cpap n-cpap n-cpap n-cpap OSAHS n-cpap ( ) 17
n-cpap n-cpap 18
n-cpap n-cpap 19
OSAHS n-cpap 10 OSAHS n-cpap MRI MRI 10 20
21
n-cpap OSAHS n-cpap n-cpap 22
SAS 87 George SAS SAS SAS SAS SAS SAS 02 03 4 SAS 616 5 25.5 03 2 26 SAS JR SAS 03 3 14 SAS 14 23
SAS n-cpap BMI 30 SAS 15 SAS SAS PSG PSG SAS PSG SAS 24
n-cpap SAS PSG MSLT SAS QOL 25
S.A.S. S.A.S. S.A.S. 14 S.A.S. CPAP S.A.S. 26
S.A.S. 27
( ) 2 ( )