2004.3.2 DI 22-2668 15 10 WHIWomen s Health Initiative 15 8 Million women study HRT :1.24 2 1 :1.45 14 :1.74 59 :2.17 10 :2.31 HRT 1 :1.81 HRT :1.31 HRT 65 :2.05 CKCPK http://www.pharmasys.gr.jp http://www.mhlw.go.jp
5mg 2001 10 2004 1 76 125mg HIV HIV HIV CD4 500/mm 3 1 1,250mg 1 2 1 750mg 1 3 HIV cap 50mg 1 200mg 1 2 1 3 1 3 ph 6.0 0.22 100mg 5mL 15 28 3 1
BUN/ Japan Coma Scale 100 DIC BUN ASTGOTALTGPT LDH CKCPK BUN/ Japan Coma Scale 100
DIC 0.22 3 0.27%5 /1,862 3 1.41%12 /852 (1) (2) cap cap Cmax6.6 AUC4.6 100 1 40mg/kg 20mg/kg 1mg/kg
cap 35mg/m 2 1 1 1 35mg/ m 2 1815 4 48 6 Lyell cap cap 2hr 1hr 2hr Child-Pugh 1 600mg 1 3 P4503A4CYP3A4 CYP3A4 cap 2hr 1hr 2hr 2 600mg8hr 800mg8hr 300mg1 1 150mg1 1 2 AUC 800mg8hr 34% 33% AUC 300mg1 1 173% 55% HIV 2 600mg8hr 800mg8hr 200mg1 1 AUC Cmax 31%16% HIV CYP3A4 BUN
cap B C Cmax AUC 32% 38% HIV 1,200mg/12 600mg/ Cmax33%AUC24% Cmin43% CYP3A4 12 15 15
1.5L 2,162.0 UV 2003.6.16 5mg 10mg 154.0 288.4 Oxycodone HCl 20mg 40mg 540.1 1,011.5 2003.7.7 5mg 10mg 20mg 40mg Cap LPV 133.3mg RTV 33.3mg 262.9 Lopinavir(LPV)Ritonavir(RTV) HIV LPV RTV 2000.12.25 16mg 90.0 Azelnidipine 1 1 24 2003.5.20 PF 2%/5mL 529.8 (5mL) Cromoglicate Na 1 2003.9.24 10mg 155.6 Loratadine H1 2002.9.2 300mg 249.2 Telithromycin 2003.12.15 100mg 150.2 Prulifloxacin ( ) 2002.12.6
40mg 170.5 Sotalol HCl Ca 1999.1.12 HD 98.6g /100g 16.7 10g Barium sulfate X P 2000.8.10 N 300U 02,462.0 /3mL/ 10R 2,462.0 30R 2,462.0 50R 2,462.0 10R50R 2003.7.4 1,500U /V 500mg /100mL / 96,872.0 Human Antithrombin AT 1,500U/ P(500)3111,180 (1,500)1 96,872 2001.10.10 2,112.0 Pazufloxacin mesilate 2002.9.2 10mg 6.4 Pyridoxal phosphate B 6 1963.11.15 V0.6 13.8mg /0.6mL 13,732.8 Hyaluronate Na 2003.2.13 250mg 35.6 Sevelamer HCl CaAl Ca 2003.6.26 PF 2%/5mL 1,262.5 (5mL) Carteolol HCl 1 2% 2003.9.24
200mg /2.5mL/V 400mg /5mL/V MS 20,000U /0.5g 90g/V 180g/V 1,1439.0 2,1783.0 0.5mL/V 2,818.0 Fosfluconazole 3 200 2004.1.15 151.0 Pronase 1995.6.12 15,634.0 Peginterferon--2a 30,587.0 --2a C IFN 180 1 IFN600 U 3 2003.12.12 B B -HB 1988.6.20 15mL 10,794.0 Meglumine gadoterate / MRI Gd 14,059.0 14,068.0 2001.4.20 25mg 02,503.3 Folinate CaLV QOL 2003.9.19 2mg 175.2 Pitavastatin Ca HMG-CoA LDL CYP 2003.9.12 PF 0.1%/5mL 161.5 (5mL) Betamethasone Na Phosphate 1 2003.9.24
20mg/ 1,171.0 Sumatriptan 5-HT 1B/1D 2003.6.9 7,719.5 Desmopressin acetate 500g 10 /5mL/ 2003.6.24 Cap 10mg 183.0 Ciclosporin 2000.5.12 100mg/mL 1,371.1 Ciclosporin (1mL) 2000.5.12 00.2mg/ 285.2 Tacrolimus hydrate (1 ) 2001.7.24 25mg/A 2,377.0 Nicardipine HCl 50mg 2A 10mg 5A 25mg24,754.0 10mg55,325.0 1999.7.5
6,000U 11,625.0 Epoetin / 6,000U/V 2003.4.7 83% 69.7 1g 10,000U / 960 U /V Colestimide 70% 2002.10.8 1805.7 Thrombin 5,000U/V 2003.7.1 11,683.0 Interferon-1b 2003.12.8 Cap 250mg 10.6 Mefenamic acid Cap 1966.7.15
25g 6,000U/V 6,000U/ 70% 83% 5g/50mL/ 200mg/100mL/V 50mg/5mL/V 5,000U/V 10,000U/ T 10%1,000mL/ P 100g HD 56mg/5mL/A 960 U/V CMV 2.5g/V 10R 300U/3mL/V 10R (300U/3mL/) 50R 300U/3mL/V 50R (300U/3mL/) 6mg Cap Metha
P.15 P.21 P.21
P.26 P.30 P.64
P.68
P.79 P.123 P.98
P.123
P.135 P.159 P.151
P.171 P.188
P.251 P.253
P.254 P.273
P.274 P.330 P.329
P.333 P.336 P.360
P.378 P.380
P.383
P.406 P.386 P.396
P.409
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