65 195 21 18% 2525 2% 3121 215 25% 1 2 2 high turnover D low turnover cortical bone 64 No.29 November 24
Technical Reports cancellous bone 1 X CT Quantitative Computed Tomography, QCT 2 2 Sound Of Speed, SOS 1 3 2 2 χ [m] t [s] c 1 K 2 ρ K 2 X Dual energy X-ray Absorption, DXA 2 X 2 SOS BUA 65
Broadband Ultrasound Attenuation, BUA.1 MHz 2 MHz P P 3 a P P Attenuation [db] 3.1 MHz 2 MHz 3 b BUA[dB/MHz] 4 BUA.1 1 SOS BUA 2 5-9 1-14 2863886 4 5 1 mm 2 SOS BUA 3.1 1 BUA 2 SOS22 27 m/s 15 m/s 66 No.29 November 24
Technical Reports BUA 2 12 1 8 6 4 2..2.4.6.8 1. 1 3-1 -2 2 4 6 8 1 2..2.4.6.8 1. 4 1 MHz 9 4 3 2 1 2 1..2.4.6.8 1. 2-1 15-2 2 4 6 8 1 2 1..2.4.6.8 1. 1-1 2 4 6 8 1 5 9 X QCT 6 6 9 BUA BUA 6 a BUA BUA 67
in vivo SOS BUA 15 7 Quality of Life 7 68 No.29 November 24
Technical Reports 1 : 1, 1, 1-4 24. 2 Consensus Development of Conference: Diagnosis, prophylaxis and treatment of osteoporosis, The American Journal of Medicine, 94, 646-65 1993. 3,,, 13, 1995. 4 C. M. Langton, S. B. Palmer and R. W. Porter, The measurement of broadband ultrasonic attenuation in cancellous bone, Engineering in Medicine, 13, 89-91, MEP Ltd. 1984. 5 A. Hosokawa and T. Otani, Ultrasonic wave propagation in bovine cancellous bone, Journal of the Acoustical Society of America, 11, 558-562 1997. 6 A. Hosokawa, T. Otani, T. Suzaki, Y. Kubo and S. Takai, Influence of Trabecular Structure on Ultrasonic Wave Propagation in Bovine Cancellous Bone, Japanese Journal of Applied Physics, 36, Pt. 1, 3233-3237 1997. 7 A. Hosokawa and T. Otani, Acoustical anisotropy in bovine cancellous bone, Journal of the Acoustical Society of America, 13, Pt. 1, 2718-2722 1998. 8,, Osteoporosis Japan, 11, 311-316 23. 9,, US23-95, 24. 1 T. J. Haire and C. M. Langton, Biot Theory: A Review of Its Application to Ultrasound Propagation Through Cancellous Bone, Bone, 24, 291-295, Elsevier Science Inc. 1999. 11 E. R. Hughes, T. G. Leighton, G. W. Petley and P. R. White, Ultrasonic propagation in cancellous bone: A new stratified model, Ultrasound in Medicine and Biology, 25, 811-821, Elsevier Science Inc. 1999. 12 T. Otani, R. Takatsu and S. Tanaka, Modelization of acoustic path of cancellous bone and quantitative estimation of bone density, Proceedings of Ultrasonics World Congress 23, 1165-1168, ISBN 2-952115- -6, Societe Francaise d Acoustique 23. 13 L. Cardoso, A. Meunier and C. Oddou, Theoretical and experimental ultrasonic characterization of anisotropic properties in cancellous bone, Proceedings of Ultrasonics World Congress 23, 1169-1172, ISBN 2-952115--6, Societe Francaise d Acoustique 23. 14 R. Barkmann, W. Timm, R. Scheffzcyk, E-M. Lochmuller and C-C. Gluer, Fast wave propagation in the epiphysis of human finger phalanges-associations between ultrasound variables and structure of trabecular bone, Proceedings of Ultrasonics World Congress 23, 1173-1176, ISBN 2-952115--6, Societe Francaise d Acoustique 23. 15 P. H. F. Nicholson, Quantitative ultrasound of bone: Myth and reality, Proceedings of Ultrasonics World Congress 23, 883-889, ISBN 2-952115--6, Societe Francaise d Acoustique 23. Hiroki Nagaoka Takuji Suzaki Takahiko Otani, DSc. Isao Mano Kaoru Horii 69