http://www.ais.cmc.osaka-u.ac.jp/~shimojo www.biogrid.jp High-Performance Distributed Computing Metacomputing[Smarr87] The GRID [Foster98] book picture here GlobusNinf Web computing OGSA IT Peer-to-peer Grobal Forum IBM,HP,SUN
Science Technical challenge of PC HPC/Distributed Computing Meets Internet
: 80-90 - I-Way 1995 feasibility Alliance (NCSA) Virtual Machine Room PACIs (NCSA/SDSC NSF National Technology ) 1998 NASA Information Power 1999~ ASCI DISCOM 1999~ GriPhyN ( Physics Network), PPDG, 2000~ e (European ), (EU/CERN) Data, 2000~ Ap (Asia-Pacific ) 2000~ NCSA-SDSC Distributed Terascale System 2001~, IDVGL (Distributed Virtual Lab) 2001~ US Blue ribbon panel on Cyberinfrastracture 4.3 6.5 (750 ) EU (6th Initiative) 3Euro, R&D 3Euro4 ( 650 /4) NaReGi (National Research Initiative) 5 100TFlops Thanks to Dr. Matsuoka
(2002) Ap 514 17( ) PRAGMA(Pacific Rim and Middleware Assembly ) 711 12( 123,24( ) with APAN, (2003) PRAGMA(Pacific Rim and Middleware Assembly ) 123,24( ) with APAN, C) with Fran Berman GGF7 at Shinjuku (3/4/2003-3/6/2003) Life Science mini workshop (3/5, 6) NaReGi cc (5/2003)
C) IT [2001/10-2005/3] A05: NII SINET [2001/10-2005/3] GRID NECSX5GLOBUS ITBL (IT based Laboratory) IT NaReGi (National Research Initiative) NaReGI: National Research Infrastructure (2003-2007) IT SuperSINET 20034 PL( ) ( ) ( ) ) 7 NII ( GSIC/NII) ( R&D ( ) ( )) ( ) ACT-JST ITBL IT R&D (NII) AIST (SuperSINET)
RPC, MPI F,H,N NII,F,H,N PSE NII,F,H,N / / FTP
(IT),
Si Si Si Si Si MPLS 500M- 622M; VLAN 200M(ITBL), 200M (Internet-SINET), 100M(Bio-) jm20-tao OC-3 su1i-cmc001 134M Si al04-cmc007 al08-handai bd16-cmc002bd16-cmc001 jm20-cmc001, jm20-cmc002 200M jm20-ext 200M GSR12400 100M Super SINET 622M HW MPLS 200M 200M 100M SINET ITBL Super Computer 1 SDSC USA SPring-8 BII Singapore 1) 2) IPv6 (6) XML 3) ASP 4) XML
1), NEC 2) SPring-8 3), 4), 5) SDSC NEC BII QoS (Quality of Service) IPv6/IPSec E-Commerse, E-Business ITBL GRID Everything on IPv6 QoS
in silico Intelligent Intelligent Intelligent
Quantum Mechanics Calculations Molecular Mechanics Calculations by AMOSS (NEC by presto ( 1,100 HOMO K + - ( ( - SPring-8 XML DNA
DB DB DB DB DB DB DB DNA (PDB) (SWISS-PROT)
XML XML-DB DB XML DB XML XML DB XML-DB PRF DB DB XML XML XML XML DB XML (flat file) PDB, PIR XML SWISS-PROT XML XML-DB XML-DB XML-DB (UHVEM) (MEG) Spring-8 (E-Science) Intelligent
R&D of biogrid software Molecular simulation [MD] [Molecular orbital method] Protein structural analysis Genome data analysis [Mutual comparison, reference, and a classification of genome data] Clusters (I) Pentium IV 1.7-2.0GHz R&D of Biogrid core Software (middleware) 16CPU High-speed processing of large-scale data Secure data sharing Pentium III 1.13GHz Dual 76node 152CPU Clusters (II) ODINS High-speed campus network Large-scale bio database Datagrid disk Clusters (III) High-speed network Alpha 1GHz Dual 64GB memory 4node 8CPU High-speed network connection equipment Pentium III 700MHz Quad 16 CPU Intramural 15TB related department etc. Protein solid structure DNA sequence Pragma 3 rd GGF7 Life Science Workshop
Technical Challenge of Coordinated Computing Knowledge Knowledge Knowledge Knowledge Computing Computing Computing Data Data Data Data http://birn.ncrr.nih.gov/
Molecules Synchrotrons Macromolecular Complexes, Organelles, Cells Microscopes Magnetic Resonance Imagers Organs, Organ Systems, Organisms Courtesy of Mark Ellisman THE BIOMEDICAL INFORMATICS RESEARCH NETWORK LAYOUT FOR PHASE 1 Drop the ball in the middle Courtesy of Mark Ellisman
24x7 Operations Monitoring BIRN Network Operations Center (NOC) Logical Description with Standardized Site Rack BIRN NOC Monitoring Internet 2 SDSC Network Network Switch BIRN Statistics BIRN Network Probe Network Attached Storage POP/ SRB, Globus Dual Processor General purpose ( eg., encryption) UPS for Rack NCRR Cisco 4006 DL380 - Network Stats GigE Net Probe N2400 NAS 0.5-4 TB DL380 POP DL380 APC UPS BIRN Site Rack NOC Servers and Testers/Analyzers Si Si GB Switches Gigabit Network Probes BIRN Network Management Courtesy of Mark Ellisman IT
( ) DR 6 1 WG 727 81 820 BERI,BGBC,
, GSI-SFS) (MEG) <hard+soft> XML World-wide Collaborative Research Activity SC2002, PRAGMA GGF Life-Science workshop Web computing