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Japanese Translation of the Cochrane Review Abstracts, and Others 10 th Minds Seminar Development, Distribution and Utilization of the Cochrane Reviews: Role of EACA Part Two: Translation of Cochrane Reviews in East Asian Countries 28 January 2011 (Sat), Tokyo Kiichiro TSUTANI MD, PhD 津谷喜一郎 Chair, Committee of HTA, Minds; Dept. of Drug Policy and Management, Grad. School of Pharm. Sciences, The University of Tokyo 1 7,000 6,000 5,000 4,000 New Protocols this issue Protocols (under reviewing) Updated reviews this Issue New reviews this Issue Total reviews produced to date (sum of new reviews), less new reviews this issue, less updated reviews this issue 3,000 2,000 1,000 0 1995/1 1995/2 1996/1 1996/2 1996/3 1997/1 1997/2 1997/3 1997/4 1998/1 1998/2 1998/3 1998/4 1999/1 1999/2 1999/3 1999/4 2000/1 2000/2 2000/3 2000/4 2001/1 2001/2 2001/3 2001/4 2002/1 2002/2 2002/3 2002/4 2003/1 2003/2 2003/3 2003/4 2004/1 2004/2 2004/3 2004/4 2005/1 2005/2 2005/3 2005/4 2006/1 2006/2 2006/3 2006/4 2007/1 2007/2 2007/3 2007/4 2008/1 2008/2 2008/3 2008/4 2009/1 2009/2 2009/3 2009/4 2010/1 2010/2 2010/3 2010/4 2011/1 2011/2 Japanese trans of CR abstract: ca 1,300 Trans. by JANCOC 481 * JANCOC (Japanese informal Network for the Cochrane Collaboration) Trans. by Minds 28% of CR abstracts is available in Japanese at Minds website 1

Early days of Japanese Translation by voluntary group in JANCOC 3 Translation by JANCOC (1997-1998) JANCOC: Japanese informal Network of The Cochrane Collaboration Translated from 1997 Issue 3 1998 issue 4; 6 issues, i.e., 18 months Draft translation: ca 15 pharmacists Checkers : ca 15 MDs Target: All Cochrane Review abstracts 481 abstract Voluntary base Abandoned in 1999 because of difficulty of management of editing work, not because of translation work. 4 2

JANCOC: 開店休業状態 inactive since 2007 5 7,000 6,000 5,000 4,000 New Protocols this issue Protocols (under reviewing) Updated reviews this Issue New reviews this Issue Total reviews produced to date (sum of new reviews), less new reviews this issue, less updated reviews this issue 3,000 2,000 1,000 0 1995/1 1995/2 1996/1 1996/2 1996/3 1997/1 1997/2 1997/3 1997/4 1998/1 1998/2 1998/3 1998/4 1999/1 1999/2 1999/3 1999/4 2000/1 2000/2 2000/3 2000/4 2001/1 2001/2 2001/3 2001/4 2002/1 2002/2 2002/3 2002/4 2003/1 2003/2 2003/3 2003/4 2004/1 2004/2 2004/3 2004/4 2005/1 2005/2 2005/3 2005/4 2006/1 2006/2 2006/3 2006/4 2007/1 2007/2 2007/3 2007/4 2008/1 2008/2 2008/3 2008/4 2009/1 2009/2 2009/3 2009/4 2010/1 2010/2 2010/3 2010/4 2011/1 2011/2 Japanese trans of CR abstract: ca 1,300 Trans. by JANCOC 481 * JANCOC (Japanese informal Network for the Cochrane Collaboration) Trans. by Minds 28% of CR abstracts is available in Japanese at Minds website 3

Three Committee in Minds 1. June 2003 CPG Selection Committee ( 診療ガイドライン選定部会, 前 診療ガイドライン選定委員会 ) 2. June 2003 Committee for EBM Promotion and Education (EBM 普及啓発部会, 前 医学文献評価選定委員会 ) 3. April 2005 Committee for HTA ( 医療技術評価部会 ) 7 Scope of Japanese Translation of Cochrane review abstract Scope: 1) Cochrane Reviews which is related to CPGs selected and posted in Minds website 2) Areas by two voluntary groups i) Oral health ii) Antismoking 8 4

The number of CPGs on Minds website 14 80 the number of CPGs 12 10 8 6 4 70 60 50 40 30 20 1 st ed. 37 2 nd ed. 24 3 rd ed. 10 4 th ed 0 5th ed 0 6 th ed. 1 total 72 2 0 2004 2005 2006 2007 2008 2009 2010 2011 10 0 Nearly half of CPGs on Mind website is 2 nd edition and more. 9 7,000 6,000 5,000 4,000 New Protocols New protocols this Issue Updated reviews this Issue New reviews this Issue Total reviews produced to date (sum of new reviews), less new reviews this issue, less updated reviews this issue 3,000 2,000 1,000 0 1995/1 1995/2 1996/1 1996/2 1996/3 1997/1 1997/2 1997/3 1997/4 1998/1 1998/2 1998/3 1998/4 1999/1 1999/2 1999/3 1999/4 2000/1 2000/2 2000/3 2000/4 2001/1 2001/2 2001/3 2001/4 2002/1 2002/2 2002/3 2002/4 2003/1 2003/2 2003/3 2003/4 2004/1 2004/2 2004/3 2004/4 2005/1 2005/2 2005/3 2005/4 2006/1 2006/2 2006/3 2006/4 2007/1 2007/2 2007/3 2007/4 2008/1 2008/2 2008/3 2008/4 2009/1 2009/2 2009/3 2009/4 2010/1 2010/2 2010/3 2010/4 2011/1 2011/2 Japanese trans of CR abstract: ca 1,300 Trans by JANCOC 481 * JANCOC (Japanese informal Network for the Cochrane Collaboration) Trans by Minds 28% of CR abstracts is available in Japanese at Minds website 5

Process and quality control of Japanese translation of CPG-related CR Step 1 Draft translation by commercial translation company. Chosen thru bidding including test translation of three abstracts, every year until 2010. Every 5 year since 2011 Translation manual, including Japanese translation of the Glossary of Clinical Evidence 11 Step 2: Checked by 13 health professionals 内科 Internist 4 消化器内科 Gastrologist 2 循環器内科 Cardiologist 1 外科 Surgeon 1 小児科 Pediatrician 1 家庭医学 Family medicine 1 歯科 Dentist 1 助産学 Midwifery 1 老年看護学 Nursing for elderly 1 They are paid for their work by Minds 12 6

Two type of Japanese translation of CR abstract Difference between 翻訳 and Draft 翻訳 例 (e.g. Cerebral Infarction) 全 145 件のうち上位 5 件 ( すべて翻訳 ) 下位 5 件 ( すべて Draft 翻訳 ) 13 14 7

15 翻訳 の box ご注意 : この日本語訳は 臨床医 疫学研究者などによる翻訳のチェックを受けて公開していますが 訳語の間違いなどお気づきの点がございましたら Minds 事務局までご連絡ください なお コクラン ライブラリは年 4 回改定版が発行されます Minds では最新版の日本語訳を掲載するよう努めておりますが 編集作業に伴うタイム ラグが生じている場合もあります ご利用に際しては 最新版 ( 英語版 ) の内容をご確認ください (Caution: This Japanese translation is checked by clinician, epidemiologist and others. If you find problems in translation, please contact Minds office.. Because of time lag of translation, please visit original English version when you use it. ) Draft 翻訳 の box * ご注意 : この日本語訳は 試験的翻訳 (Draft 翻訳 ) 版として公開するものであり 翻訳の正確さや質が保証されたものではありません 訳語の間違いなどお気づきの点がございましたら Minds 事務局までご連絡下さい また この試験的翻訳版はコクラン ライブラリ 2005 年 issue 4 に掲載されたレビュー アブストラクトの翻訳です コクラン ライブラリは年 4 回改定版が発行されていますので ご利用に際しては 最新版 ( 英語版 ) の内容をご確認下さい (Caution: This English translation is draft translation and its correctness and quality is not validated. ) 16 8

Draft 翻訳 17 Open access to Minds website since 2008 Before After non-login system introduced At the end of September 2008 18 9

Rank Top 20 access to disease groups Before (May 2008) After (February 2009) user access Disease group 1 447 oral health 2 79 decubitus 3 60 ulcerative colitis 4 56 breast cancer 5 50 cerebral infarction 6 45 asthma 6 45 lung cancer 8 38 osteoporosis 9 30 diabetes mellitus 9 30 gastric cancer 9 30 pancreatic cancer 12 29 colon cancer 13 27 prostate cancer 14 21 gastric ulcer 15 20 anterior cruciate ligament injury 16 19 Alzheimer-type dementia 17 18 ischemic heart disease 18 17 intracranial hemorrhage 18 17 cataract 18 17 hip fracture/trochanteric fracture 18 17 hepatoma Rank user access Disease group 1 3075 oral health 2 2107 cerebral infarction 3 1704 diabetes mellitus 4 1694 asthma 5 1677 Alzheimer-type dementia 6 1612 low back pain 7 1315 decubitus 8 1213 colon cancer 9 1086 hip fracture/trochanteric fracture 10 1083 breast cancer 11 940 intracranial hemorrhage 12 896 acute myocardial infarction 13 853 lung cancer 14 841 osteoporosis 15 816 ulcerative colitis 16 808 subarachnoid hemorrhage 17 633 acute cholangitis, cholecystitis 18 604 hypertension 19 598 acute otitis media in children 20 521 chronic heart failure Total number of user access: 1,273 Total number of user access: 31,877 19 Top 20 access to the Cochrane Reviews Before (May 2008) Rank user access Disease group Title 1 25 oral health Manual versus powered toothbrushing for oral health. 2 24 oral health Antibiotics to prevent complications following dental implant treatment. 3 19 decubitus Nutritional interventions for preventing and treating pressure ulcers. 4 17 pancreatic cancer Chemotherapy and radiotherapy for inoperable advanced pancreatic cancer. 4 17 oral health Interventions for replacing missing teeth: 1- versus 2-stage implant placement. 4 17 oral health Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate, immediate-delayed and delayed implants). 7 15 gastric cancer Chemotherapy for advanced gastric cancer. 7 15 decubitus Support surfaces for pressure ulcer prevention. 7 15 oral health Fluoride mouthrinses for preventing dental caries in children and adolescents. 10 14 gastric cancer Endoscopic mucosal resection for early gastric cancer. 10 14 decubitus Wound cleansing for pressure ulcers. 12 13 decubitus Topical silver for treating infected wounds. 12 13 oral health Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride for preventing dental caries in children and adolescents. 12 13 oral health Fluoridated milk for preventing dental caries. 15 12 oral health Fluoride gels for preventing dental caries in children and adolescents. 15 12 oral health Recall intervals for oral health in primary care patients. 17 11 colon cancer Colorectal Meta-analysis Collaboration. Palliative chemotherapy for advanced or metastatic colorectal cancer. 18 10 pancreatic cancer Endoscopic retrograde cholangiopancreaticography with or without stenting in patients with pancreaticobiliary malignancy, prior to surgery. 18 10 asthma Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children. 18 10 oral health Interventions for replacing missing teeth: treatment of perimplantitis. 20 10

rank Top 20 access to Cochrane Reviews user access Disease group Title 1 545 low back pain Back schools for non-specific low-back pain. 2 209 low back pain Low level laser therapy for nonspecific low-back pain. 3 180 decubitus Wound cleansing for pressure ulcers. 4 142 decubitus Risk assessment tools for the prevention of pressure ulcers. 5 114 decubitus Nutritional interventions for preventing and treating pressure ulcers. 6 100 decubitus Topical negative pressure for treating chronic wounds. 7 99 hip fracture/ trochanteric fracture Gamma and other cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures in adults. 7 99 Alzheimer-type dementia Galantamine for Alzheimer's disease and mild cognitive impairment. 9 96 gastric cancer Chemotherapy for advanced gastric cancer. 9 96 hip fracture/ trochanteric fracture Conservative versus operative treatment for hip fractures in adults. 11 89 colon cancer Quality of life after rectal resection for cancer, with or without permanent colostomy. 12 88 colon cancer Early enteral nutrition within 24h of colorectal surgery versus later commencement of feeding for postoperative complications. 13 85 acute otitis media in children Pneumococcal vaccines for preventing otitis media. 14 83 lumbar disc herniation Rehabilitation after lumbar disc surgery. 15 81 acute myocardial infarction Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft. 16 80 cervical degenerative disc disease After (February 2009) Single or double-level anterior interbody fusion techniques for cervical degenerative disc disease. 17 79 arrhythmia Electrical cardioversion for atrial fibrillation and flutter. 18 77 decubitus Topical silver for treating infected wounds. 21 Order of Minds in web search of コクラン (Cochrane) September 2008 October 2008 November 2008 December 2010 Google 292 33 28 13 Yahoo 132 81 82 12 MSN 66 51 32 30 non-login system introduced at the end of September 2008 22 11

Minds user survey E-mail survey to 35,000 users in mailing list of Minds from Dec. 2010 to Feb. 2011 2,940 (8.4%) responded 20 歳代以下 30 歳代 40 歳代 50 歳代 60 歳代 70 歳代以上 医療関連職 医療提供者 一般 0 200 400 600 800 1000 1200 1400 23 自分の健康家族や友人 知人の健康学習や知識習得その他 医療関連職 医療提供者 一般 0 500 1000 1500 2000 2500 24 12

Satisfaction on each data source of Minds 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% CPG 医療提供者向け GL Minds アブストラクト 医療提供者医療系学生医療関連職一般 CR abstracts コクラン レビュートピックス CPG レビュー一般向け GL やさしい解説 GL 解説 利用者 医療提供者 医療系学生 医療関連職 一般 ( コンテンツ区分 ) 医療提供者向けGL 92% 88% 91% 83% Mindsアブストラクト 70% 74% 69% 66% コクラン レビュー 72% 62% 74% 76% トピックス 59% 29% 62% 53% CPGレビュー 57% 42% 48% 54% 一般向けGL 72% 76% 71% 80% * やさしい解説 74% a 64% 77% 88% a GL 解説 66% 56% 72% 80% CPG for patients * はコンテンツ区分と利用者種別のクロス集計の独立性の検定 (χ 二乗 ) において有意な差が認められたことを意味する (p < 0.001) 肩付のアルファベットは 同一のアルファベット間に有意な差が認められたことを意味する (p < 0.001) Hatakeyama Y. 2012 25 Others Japanese Hand Search and Electronic Search Project (JHES) 26 13

27 Hand searched journal and identified RCTs 1. 臨床評価 401 (completed 00. 12.1) 2. 薬理と治療 912 (completed 04.8.16) 3. 臨床と研究 752 (completed 04.4.9) 4. 基礎と臨床 807 (completed 07.8.4) 5. Therapeutic Research 270 (completed 10.4.19) 6. 日本看護科学会誌 5 (completed 03.3.6) 7. 麻酔 634 (completed 10.2.26) 8. 臨床医薬 962 (completed 06.5.19) 8. 医学のあゆみ ongoing 9. Other four ongoing 28 14

Summary Infrastructure type of works of translation and hand search was introduced. Those who wishes academic promotion, should not enter into this kind of work, as it is usually not recognized as academic work. 29 Thanks you 30 15