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1 NERD Year Note ATLAS MEDIC MEDIA Zollinger-Ellison
2
3 Q&A
4 Barrett ,,,.. 105(1): 54-59, Barrett. 22(1): 83-90, (1): , Kouichirou Furuta, SHuichi Sato, Tishikazu Kinoshita. Abnormal liver function in Crohn's disease related to location of Disease lesions. Inflammatory Bowel Diseases 14(1): , Yuji Amano, Norihisa Ishimura, Kinoshita. The esophagogastric junction can only be assessed by histologic examination.. Gastrointestinal Endoscopy 65(1): , CMV 1. 12(2): 87-91, Miwa H, Nakajima K, Yamaguchi K, Fujimoto K, Veldhuyzen VAN Zanten SJ,Kinoshita Y, Adachi K, Kusunoki H, Haruma K. Generation of dyspeptic symptoms by direct acid infusion into the stomach of healthy Japanese subjects.. Alimentary Pharmacology and Therapeutics 26(2): , 2007
5 8. Chinuki D, Amano Y, Ishihara S, Moriyama N, Ishimura N, Kazumori H, Kadowaki Y, Takasawa S, Okamoto H, Kinoshita Y. REG Ialpha protein expression in Barrett's esophagus. Journal of gastroenterology and hepatology 23(2): , NERD NERD. G.I.Research 15(3): , Ose T, Kadowaki Y, Fukuhara H, Kazumori H, Ishihara S, Udagawa J, Otani H, Takasawa S, Okamoto H, Kinoshita Y. Reg I-knockout mice reveal its role in regulation of cell growth that is required in generation and maintenance of the villous structure of small intestine.. Oncogene 26(3): , Helicobacter pylori. 22(3): , H.pylori. 4(4): 84-88, ,,,. H.pylori Helicobacter pylori. Helicobacter Research 11(4): , (4): , Therapeutic Research 28(4): , (5): , Aziz MM, Ishihara S, Rumi MA, Mishima Y, Oshima N, Kadota C, Moriyama I, Li YY, Rahman FB, Otani A, Oka A, Ishimura N, Kadowaki Y, Amano Y, Kinoshita Y. Prolactin induces MFG-E8 production in macrophages via transcription factor. Apoptosis 13(5): , (NERD). Therapeutic Research 28(5): , GERD NERD. GERD. 65(5): , 2007
6 20.. GERD NERDGERD -NERD. 65(5): , Joh T, Miwa H, Higichi K, Shimatani T, Manabe N, Adachi K, Wada T, Sasaki M, Fujiwara Y, Hongo M, Chiba T, Kinoshita Y. Validity of endoscopic classification for non-erosive reflux disease. Journal of Gastroenterology 42(6): , Amano Y, Kushiyama Y, Yuki T, Takahashi Y, Chinuki D, Ishimura N, Furuta K, Ishihara S, Adachi K, Maruyama R, Kinoshita Y.. Predictors for squamous re-epithelialization of Barrett's esophagus after endoscopic biopsy. Journal of gastroenterology and hepatology 22(6): , GERD. 99(6): , Medical Tribune 40(8): 16-17, Kouichirou Furuta, Shuichi Sato, Yoshikazu Kinoshita et al. Anti-tumor effects of cimetidine on hepatocellular carcinoma in diethylnitrosamine-treated rats. Oncology Report 19(8): , Miyake T, Sato S, Okamoto E, Ishine J, Oshima N, Azumi T, Mishiro T, Furuta K, Ishihara S, Adachi K, Amano Y, Kinoshita Y. Feru-Carbotran expands area treated by radiofrequency ablation in rabbit livers. Journal of gastroenterology and hepatology 23(9): , Gastroenterological Endoscopy 49(9): , (10): , NSAID NSAID. 65(10): , (11): , Furuta K, Adachi K, Arima N, Yagi J, Tanaka S, Miyaoka Y, Miki M, Azumi T, Koshino K, Ishihara S, Amano Y, Kinoshita Y. Study of arteriosclerosis in spatients with hiatal hernia and reflux esophagitis. Journal of gastroenterology and hepatology 22(11): , (11): , 2007
7 33.,,,,.. 104(12): , DATA. 56(): , Chan FKL, Gold BD, Kinoshita Y, Chan AOO, Wong MSR, Makmun HD, Ovarlarnporn B, Vivatvakin B, Lin JT, Sheu BS, Chang WH. Introduction:current practice in acid-related disorders in Asian countries, and workshop backgraund, design and goals. Alimentary Pharmacology and Therapeutics sinposium series 3: 1-5, : 4-5, MEDICAMENT NEWS 1914: 20-23, Kinoshita Y. Review article: management issues in acid-velated disorders in the elderly. Alimentary Pharmacology and Therapeutics symposium series3: 21-26, Chan FKL, Kinoshita Y. Review article: building an algorithm for the management of geriatric acid-related disorders in Asia. Alimentary Pharmacology and Therapeutics symposium series3: 27-30, Gold BD, Kinoshita Y, Chang WH, Vivatvakin B, Ovarlarnpont B, Chan FKL. Review article: exploring strategics to improve treatment outcomes and compliance in specific patient groups with acid-related disorders. Alimentary Pharmacology and Therapeutics symposium series3: 31-34, Barrett Prague C, M. Review of Gastroenterology&Clinical Gastroenterology and Hepatology 2: 32-34, : 45-49, Network 8: 52-53, : 53-59, Miwa H, Sasaki M, Furuta T, Koike T, Habu Y, Ito M, Fujiwara Y, Wada T, Nagahara A, Hongo M, Chiba T, Kinoshita Y, ARS Research Group. Efficacy of proton pump inhibitor, rabeprazol, on heartburn symptom resolution in patients with non-erosive and erosive gastro-oesophageal reflux disease- a maiticenter
8 study from Japan. Alimentary Pharmacology and Therapeutics 26: 69-77, PPI (Q&A). 4643: 91-92, Internal Medicine 46: , : , GERD. Frontiers in Gastroenterology 12: , Frontiers in Gastroenterology 12: , Overview. 4: , Current Therapy 25: , G.I.Research 15: , : , : , Functional dyspepsia 2. 41: , Moriyama I, Ishihara S, Rumi MAK, Aziz MM, Mishima Yo, Oshima N, Kadota C, Kadowaki Y, Amano Y, Kinoshita Y. Decoy oligodeoxynucleotide targeting activator protein-1(ap-1) attenuates intestinal inflammation in marine experimental colitis. Laboratory investigation 88: , Hongo M, Kinoshita Y, Shimozuma K, Kumagai Y, Sawada M, Nii M. sychometric validation of the Japanesee translation of the Quality of Life in Reflux and Dyspepsia questionnaire in patients with heartburn. Journal of Gastroenterology 42: , GERD. 65: , 2007
9 60. Furuta K, Adachi K, Arima N, Yagi J, Tanaka S, Miyaoka Y, Miki M, Azumi T, Koshino K, Ishihara S, Amano Y, Kinoshita Y. Study of arteriosclerosis in patients with hiatal hernia and reflux esophagitis. Journal of gastroenterology and hepatology 22: , Chinuki D, Amano Y, Ishihara S, Moriyama N, Ishimura N, Kazumori H, Kadowaki Y, Takasawa S, Okamoto H, Kinoshita Y. REG1-alpha protein expression in Barrette's esophagus. Journal of Gastroenterology and Hepatology 23(2): , Miyake T, Sato S, Okamoto E, Ishine J, Oshima N, Azumi T, Mishiro T, Furuta K, Ishihara S, Adachi K, Amano Y, Kinoshita Y. Ferucarbotran expands area treated by radiofrequency ablation in rabbit livers.. Journal of Gastroenterology and Hepatology 23(7 Pt2): e270-e274, Furuta K, Sato S, Miyake T, Okamoto E, Ishine J, Ishihara S, Amano Y, Adachi K, Kinoshita Y. Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. Oncology Reports 19(2): , Azumi T, Adachi K, Arima N, Tanaka S, Yagi J, Koshino K, Miki M, Furuta K, Kioshita Y. Five-year follow up study of patients with reflux symptoms and reflux esophagitis in annual medical check-up field.. Internal Medicine 47(8): , Shibagaki K, Hujita K, Nakayama S, Takenaka M, Hukuba N, Matsui S, Ozaka M, Yoshinaga H, Masuzawa A, Watanabe A, Hujiwara H, Sugawara A, Hujita T, Mukai H, Kinoshita Y. Complete response of a pancreatic adenosquamouse carcinoma to chemoradiotherapy. International Journal of Clinical Oncology 13: 74-77, Furuta K, Sato S, Miyake T, Okamoto E, Ishine J, Ishihara S, Amano Y, Adachi K, Kinoshita Y.. Abnormal liver function in Crohn's disease related to location of disease lesions.. Inflammatory Bowel Disease 14(1): , Amano Y, Kinoshita Y. Barrett Esophagus: Perspectives on its diagnosis and management in Asian population. Gastroenterology and Hepatology 4: 45-53, Honda C, Adachi K, Arima N, Tanaka S, Yagi J, Morita T, Tanimura T, Furuta Ke, Kinoshita Y. Helicobacter pylori infection dose not accelerate the age-related progression of arteriosclerosis: a 4-year follow-up study. Journal of Gastroenterology and Hepatology 23: e373-e378, Moriyama I, Ishihara S, Rumi MA, Aziz MD, Mishima Yo, Oshima N, Kadota C, Kadowaki Y, Amano Y, Kinoshita Y. Decoy oligodeoxynucleotide targeting
10 activator protein-1(ap-1) attenuates intestinal inflammation in murine experimental colitis. Labolatory investigation 88: , Aziz MM, Ishihara S, Rumi MAK, Mishima Yo, Oshima N, Kadota C, Moriyama I, Li YY, Rahman FB, Otani A, Oka A, Ishimura N, Kadowaki Y, Amano Y, Kinoshita Y. Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPβ-dependent pathway. Apoptosis 13(5): , Mishima Yu, Amano Y, Okita K, Takahashi Y, Moriyama N, Ishimura N, Furuta Ke, Ishihara S, Adachi K, Kinoshita Y. Efficacy of prokinetic agents in improving bowel preparation for colonoscopy. Digestion 77(4): , Azumi T, Adachi K, Furuta Ke, Nakata S, Ohara S, Koshino K, Miki M, Morita T, Tanimura T, Ashizawa N, Kinoshita Y. Esophageal epithelial surface in patients with gastroesophageal reflux disease: An electron microscopic study. World Journal of Gastroenterology 14: , Yuki M, Kazumori H, Yamamoto S, Shizuku T, Kinoshita Y. Prognosis following endoscopic injection sclerotherapy for esophageal varices in adults: 20-year follow-up study. Scandinabian Journal of Gastroenterology 43: , Imaoka H, Amano Y, Moriyama I, Itoh S, Yanagisawa A, Kinoshita Y. Endoscopic ultrasound-guided fine-needle aspiration of a mixed acinar-endocrine carcinoma: a case report. The American Journal of Gastroenterology 103: , Okita K, Amano Y, Takahashi Y, Mishima Y, Moriyama N, Ishimura N, Ishihara S, Kinoshita Y.. Barrett s esophagus in Japanese patients: its prevalence, form and elongation.. Journal of Gastroenterology 43(12): , Kinoshita Y, Ishihara S. Causes and therapeutic approaches for PPI-resistans GERD in Asia. Therapeutic Advances in Gastroenterology 1: , Moriyama N, Amano Y, Mishima Y, Okita K, Takahashi Y, Yuki T, Ishimura N, Ishihara S, Kinoshita Y.. What is the clinical significance of stromal angiogenesis in Barrett s esophagus?. Journal of Gastroenterology and Hepatology 23(S2): , Hongo M, Kinoshita Y, Haruma K. A randomized, double-blind, placebo-controlled clinical study of the histamine H2-receptor antagonist famotidine in Japanese patients with nonerosive reflux disease.. Journal of Gastroenterology 43(6): , Hongo M, Kinoshita Y, Miwa H, Ashisa K. The demopraphic characteristics and health-relatednquality of life in a large cohort of reflux esophagitis patients in Japan with reference to the effect of lansoprazole: the REQUEST study. Journal of Gastroenterology 43: , 2008
11 80. Amano Y, Yamashita H, Koshino K, Ohshima T, Miwa H, Iwakiri R, Fujimoto K, Manabe N, Haruma K, Kinoshita Y. Does magnifying endoscopy improve the diagnosis of erosive esophagitis?. Journal of Gastroenterology and Hepatology 23(7): , Kinoshita Y, Ozawa S.. New knowledge and issues to be solved convening gastroesophageal reflux disease. Esophagus 5: 13-14, Okamoto E, Amano Y, Fukuhara H, Furuta K, Miyake T, Sato S, Ishihara S, Kinoshita Y. Does gastroesophageal reflux have influence on bleeding from esophageal varices?. Journal of Gastroenterology 43(10): , GERD. Osteoporosis Japan 16: 69-71, Barrett Barrett. 10: 81-88, (1): 54-59, update GERD. 23: , : , : , GERD. 90: , : , GERD. 19: , : 24-25, 2008
12 : 95-99, Salvus 2: 7-8, FD. Medical Tribune 39541: 16-17, H. pylori NSAIDs. Clinical Magazine 464: 36-39, PPI. Ulcer Research 35: 20-24, Rome FD FD. 11: , : , Medical Practice 25: , Review of Gastroenterology & Clinical Gastroenterology and Hepatology 3: 30-36, GERD. 1: 18-25, Overview. 5: 329, Barrett. Frontiers in Gastroenterology 13: , Kusano M, Shirai N, Yamaguchi K, Hongo M, Chiba T, Kinoshita Y The Acid-Related Symptom(ARS)Research Group. It is possible to classify non-erosive reflux disease(nerd) patients into endoscopically normal groups and minimal change groups by subjective symptoms and responsiveness to rabeprazole-a report from a study with Japanese patients. Digestive Diseases and Sciences 53: , : ,
13 . H2. 6: , QOL. Progress in Medicine 28: , Barrett GERD SIGIRR TLR MFG-E8 NF- B ph Innate immunity conyrol IBD Milk fat globule-egf factor8 MFG-E8 Toll C
14 9. IPMN AP-1 dsdna decoy ManoScan360TM Barrett REQUEST study: CD5 B Nobuyuki Moriyama, Yuji Amano, Norihisa Ishimura, Shunji Ishihara, Yoshikazu Kinoshita. Clincal significance of fatty acid synthase in Barrett's esophagus.. International Symposium on Gastroenterology. Shimoda,
15 20. Barrett C M IPMN IPMN EUS GERD GERD Barrett Barrett RC sign C RVS AmanoY, Moriyama N, Okita K, Takahashi Y, Mishima Y, Ishimura N, Ishihara S, Kinoshita Y. Does aging extend Barrett's esophagus naturally?.digestive Disease Week Washington DC, Moriyama I, Ishihara S, Rumi MAK, Aziz MD, Kinoshita Y, Mishima Yo, Kadota C, Oshima N, Ishimura N, Kazumori H, Kadowaki Y, Amano Y. Decoy oligodeoxynucleotides targeting AP-1 and Nf-kB attenuate intestinal inflammation in murine experimental colitis.digestive Disease Week Washington DC, Kazumori H, Yuki M, Komazawa Y, Shizuku T, Kinoshita Y. The roles of caudal-related homeobox gene CDx1 and CDx2 in esophageal epithelial cells in Barrett's epithelium.digestive Disease Week Washington DC,
16 30. Azumi T, Adachi K, Arima N, Tanaka S, Yagi J, Koshino K, Miki M, Furuta K,. The natural history of non-erosive gastroesophageal reflux disease (NERD) in Japan: A prospective study.digestive Disease Week Washington DC, Mishima Y, Ishihara S, Rumi MAK, Aziz MD, Moriyama I, Kadota C, Oshima N, Ishimura N, Kazumori H, Kadowaki Y, Amano Y, Kinoshita Y. Toll-like receptor 9-signaling mediates innate response in murine intestinal CD5+B cells.digestive Disease Week Washington DC, Furuta Ko, Sato S, Miyake T, Okamoto E, Isshine J, Ishihara S, Amano Y, Adachi K, Kinoshita Y. Inhibition of the development of hepatocellular carcinoma by cimetidine in diethylnitrosamine-treated rats.digestive Disease Week Washington DC, Kinoshita Y, Miwa H, Ashida K, Hongo M. Dose lifestyle modification improve health-relates quality of life of patients with reflux esophagitis Who receive treatment with a proton pump inhibitor?:data from request study (4).Digestive Disease Week Washington DC, Moriyama I, Ishinara S, Rumi M, Aziz MD, Kinoshita Y, Mishima Y, Kadota C, Oshima N, Ishimura N, Kazumori H, Kadowaki Y, Amano Y. Animal models preclinical therapeutic studies of intestinal inflammation.digestive Disease Week Washington DC, Moriyama Y, Kawaguchi M, Hashimoto Y, Urakawa A, Fujii H, Adachi K. Efficacy of health food supplement fot the patients treated by pallative care team. 10th Congress of the European Assocication for Palliative Care. Budapest, Hungary, EUS-FNA) Auto-Fluorescence
17 Imaging) GERD HCV Suyama Y, Notsu Y, Fukuma E, Kawaguchi M, Hashimoto Y, Itakura M, Iijima K, Omura K, Imaoka R, Hibara C, Adachi K. Efficacy of corrected RTP increment index (CRII) for the early detection of improvement of nutrition status in patinets with low nutrition status. 29Tth ESPEN ( European Society for Parenteral and Enteral Nutrition) cogress. Prague, Czech Republic, Renal medullary fibroma GERD/NERD/FD PPI
18 51. Sanchez-Siles AA, Ishimura N, Aziz MD, Mishima Y, Ishihara S, Kinoshita Y. Reduction of copper-dependent oxidative stress by PPAR b/d agonism in HepG2 cell line and its possible implications in clinical practice. The Sixth JSH Single Topic Conference Yuji Amano. Barrett s esophagus in Japan. Asian Pacific Digestive Week Kobe, H. pylori Toll CD5 B Real-time tissue elastography HCV Barrett
19 62. NASH FNA HBs HBs HBV Peutz-Jeghers syndrome PJS FG-E8 NF-κB SIGIRR TLR GERD? Barrett
20 71. H ?? TTR Barrett fatty acid synthase nutrition support team NST ph ph M -ph ph Aziz MM
21 80. F PPI C UDCA600mg/ 900g/ NAFLD Oshima N, Ishihara S, Rumi MAK, Aziz MM, Mishima Yo, Kadota C, Moriyama I, Ohtani A, Oka A, Li YY, Kadowaki Y, AmanoY, Kinoshita Y. A20 is an early responsive negative regulator of Toll-like receptor signaling in intestinal epithelial cells during inflammatio. Digestive Disease Week San Diego, Ihsihara S, Aziz MM, Rumi MAK, Mishima Yo, Oshima N, Moriyama I, Kadota C, Li YY, Ohtani A, Oka A, Farzana RB, Ishimura N, Kadowaki Y, Amano Y, Kinoshita Y. Milk fat globule EGF-8 attenuates intestinal inflammation in murine experimental colitis via inhibition of NF-κB activation. Digestive Disease Week San Diego, Furuta Ko, sato S, Ishine J, Okamoto E, Tobita H, Miyake T, Ishihara S, Amano Y, Adachi K, Maruyama R, Kinoshita Y. Predictive factors for severity of liver histology in patients with non-alcoholic steatohepatitis: usefulness of measurement of arteriosclerosis indicators. Digestive Disease Week San Diego, Amano Y, Takahashi Y, Ishimura N, Okita K, Mishima Yu, Sanchez-Siles AA, Moriyama N, Ishihara S, Kinoshita Y. Fatty acid synthase expression in Barrett's esophagus and its detection in endoscopic surveillance. Digestive Disease Week San Diego, Kazumori H, Yuki M, Komazawa Y, Shizuku T, Kinoshita Y. Autoregulation of Cdx1 and Cdx2 in development of Barrett's epithelium. Digestive Disease Week San Diego, Mishima Yo, Ishihara S, Aziz MM, Rumi MAK, Oshima N, Kadota C, Moriyama I, Li YY, Ohtani A, Oka A, Kadowaki Y, Amano Y, Kinoshita Y. Intestinal Cd5 B cells produce IL-10 and TGF-β via Toll-like receptor-mediated signaling.
22 Digestive Disease Week San Diego, Sanchez-Siiles AA, Ishimura N, Aziz MM, Mishima Yo, Ishihara S, Kinoshita Y. Activation of PPARβ/δ reduces copper-dependant oxidative stress and FasL(Cd85l) mediated apoptosis in HepG2 cells: possible implications in clinical practice. Digestive Disease Week San Diego, Fukudo S, Hongo M, Shimosegawa T, Sasaki D, Matsueda K, Harasawa S, Miura S, Mine T, Kaneko H, Arakawa T, Haruma K, Torii A, Azuma T, Miwa H, Matsumoto T, Fukunaga M, Handa M, Kinoshita Y, Okumura T, Miwa T, IBS Club. Effect of therapeutic duideline on irritable bowel syndrome: a randomized controlled trial. Digestive Disease Week San Diego, GERD H. pylori H. pylori ERCP mixed acinar-endocrine carcinoma SEMS NASH
23 Cronkhite-Canada GERD Barrett GERD EST Inflammatory fibroid polyp IFP Koshino K, Adachi K, Furuta Ke, Kinoshita Y. The effect of nizatidine and itopride hydrochloride on the segments of esophageal body contraction. 11th World Congress of the International Society for Diseases of the Esophagus.
24 Budapest, Hungary, Furuta Ke, Adachi K, Koshino K, Kinoshita Y. The effect of antihypertensive drugs on the segments of esophageal body contraction. 11th World Congress of the International Society for Diseases of the Esophagus. Budapest, Hungary, Adachi K, Morita T, Tanimura T, Ohara S, Koshino K, Furuta Ke, Moriyama Y, Fujii H, Kawaguchi M, Kinoshita Y. Gastro-esophageal reflux events during the feeding of half-solid nutrient in patients with PEG. 30th European Society for Parenteral and Enteral Nutrition congress. Florence, Italy, A Barrett IL-10 TGF-beta B C SVR AFI
25 IPMN EEMR-tube
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