62 HSI HSI 2010 p.8 1 HSI p Paenibacillus cookii SS Paenibacillu

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1 61 Ohashi Y, Shi W, Takatani N, Aichi M, Maeda S, Watanabe S, Yoshikawa H, Omata T.Regulation of nitrate assimilation in cyanobacteria J Exp Bot. 62(4): Minami M, Aichi M, Ueno K, Terai H, Odawara T, Nasu M, Yokota S, Yonemura S, Suzuki K, Tanaka. A Outline and Use of the Experimental Urban SATOYAMA Forest at Chubu University, Aichi Prefecture, Japan. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p.353. Ajioka Y, Aichi M, Ueno K, Terai H, Minami M, Odawara T, Nasu M, Yokota S, Yonemura. S Evaluation of environmental factors for the conservation of genetic diversity in Gentiana thunbergii, the SATOYAMA indicator species. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p Yokota S, Odawara T, Nasu M, Yonemura S, Minami M, Aichi M, Ueno K, Terai H Evaluation of Species Diversity and Potential Habitats of the SATOYAMA Indicator Species in Toki-Shonai River Basin. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p Part2 in2010 DEVNET p HSI P118

2 62 HSI HSI 2010 p.8 1 HSI p Paenibacillus cookii SS Paenibacillus cookii SS

3 Aspergillus terreus Kumabe K, Sato T, Matsumoto K, Ishida Y, Hasegawa T2010Production of hydrocarbons in Fischer-Tropsch synthesis with Fe-based catalyst: Investigations of primary kerosene yield and carbon mass balance, Fuel, 89; Fischer-Tropsch Koido K, Ishida Y, Kumabe K, Matsumoto K, Hasegawa T Kinetics of ethanol oxidation in subcritical water, Journal of Supercritical fluids, 55(1); / 2011MALDI-MS :, (1): MALDI-MS 2011 : Laboratory Practice, Vol. 39(3): MALDI-MS MALDI-MS

4 /1 (MALDI-MS) (TAG) /

5 GC GC MALDI-MS MS

6 MALDI-MS l Ogimoto K, Hashimoto A, Yokoi T, Ishida Y, Okamoto A, Kawamura K Discrimination of drug resistance bacteria based on structural analysis of lipid and protein components. International Conference on Polymer Analysis and Characterization, Nagoya.

7 67 Siti Baidurah, Takada S, Shimizu K, Ishida Y, Yamane T, Ohtani H Evaluation of biodegradation behavior of poly(butylene succinate-co-butylene adipate) by reactive pyrolysis-gas chromatography in the presence of organic alkali. International Conference on Polymer Analysis and Characterization, Nagoya. (Presentation Award ) μg 1 Tsutsumiuchi K, Mukaino T, Ohno T, Yano T, Ishida Y, Kobayashi T Analysis of 4-Methylcatechol-coated Magnetite Nanoparticles by Reactive Pyrolysis-Gas Chromatography. International Conference on Polymer Analysis and Characterization, Nagoya Minami M, Aichi M, Ueno K, Terai H, Odawara T, Nasu M, Yokota S, Yonemura S, Suzuki K, Tanaka A Outline and Use of the Experimental Urban SATOYAMA Forest at Chubu University, Aichi Prefecture, Japan. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p.353. Ajioka Y, Aichi M, Ueno K, Terai H, Minami M, Odawara T, Nasu M, Yokota S, Yonemura S Evaluation of environmental factors for the conservation of genetic diversity in Gentiana thunbergii, the SATOYAMA indicator species. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p

8 68 Yokota S, Odawara T, Nasu M, Yonemura S, Minami M, Aichi M, Ueno K, Terai H Evaluation of Species Diversity and Potential Habitats of the SATOYAMA Indicator Species in Toki-Shonai River Basin. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p Part1 in2010 DEVNET p HSI P118 HSI p DNA DNA 2010 p.5 DNA rbcl Apodemus 2 DNA 2010

9 69 p p HSI 2010 p.8 1 HSI p A COD/BOD BOD

10 70 Asai M, Kawashima D, Katagiri K, Takeuchi R, Tohnai G, Ohtsuka KProtective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injurylife Sciences, 88: , Hsp70 Hsp70 Hsp70 Hsp70 Takeuchi R, Soga M, Inaguma Y, Ohtsuka K. Characterization of a novel mammalian co-chaperone, DnaJB7, an HSP40 family memberthermal Medicine, 27: 9-23, HSP40 50 DnaJB7 DnaJB7 Hsp70ATPase Hsp Hsp40 DnaJB Hsp40 DnaJB7 cdna HeLa cdna HSP SV40 Large T-antigen HSP HSP Large T-antigen HSF1 sirna HSF1 sirna Takeuchi R, Soga M, Ohtsuka K.Characterization of DnaJB7, a mammalian HSP40 (DnaJ) homolog. The 5th Asian Congress of Hyperthermic OncologyThe 27th Japanese Congress of Thermal Medicine, September 10-11, 2010, Fukuoka, Japan.

11 71 Soga M, Takeuchi R, Kawashima D, Tabuchi Y, Ohtsuka K. Functional restoration of temperature-sensitive mutant of large T-antigen by HSP inducer. The 5th Asian Congress of Hyperthermic OncologyThe 27th Japanese Congress of Thermal Medicine, September 10-11, 2010, Fukuoka, Japan. Ohtsuka K. Protein quality control by molecular chaperones and its medical applications (Educational Lecture). The 5th Asian Congress of Hyperthermic OncologyThe 27th Japanese Congress of Thermal Medicine, September 10-11, 2010, Fukuoka, Japan Hsp40(DnaJ) DnaJB SBMA 5 SBMA HSPs

12 72

13 73 Manohar SL, Kanamasa S, Nishina T, Kato T, Park EY Enhanced gene expression in insect cells and silkworm larva by modified polyhedrin promoter using repeated burst sequence and very late transcriptional factor-1. Biotechnol. Bioeng. 107: Manohar SL, Kanamasa S, Nishina T, Kato T, Park EY Enhanced gene expression in insect cells and silkworm larva by modified polyhedrin promoter using repeated burst sequence and very late transcriptional factor-1. International Conference on Cellular & Molecular Bioengineering (ICCMB2) (Singapore) Paenibacillus cookii SS

14 Paenibacillus cookii SS Aspergillus terreus

15 Penicillium sp Kojima S, Iwasaki M, Imai T, Matsumura Y, Ueno Y, Machida C#27. mutation affects leaf polarity and leaf venation patterns in Arabidopsis thaliana. The 21st International Conference on Arabidopsis Research (ICAR 2010) June, (Yokohama) #27 as2-1 Iwasaki M, Iwakawa H, Takahashi H, Pekker I, Eshed Y, Ueno Y, Kojima S, Machida Y, Machida C Dual regulation of expression of ETT/ARF3 by ASYMMETRIC LEAVES2 (AS2) and AS1 for establishment of the medial-lateral leaf polarity in Arabidopsis thaliana. The 21st International Conference on Arabidopsis Research (ICAR 2010) June, (Yokohama) ETT/ARF3 AS1 AS2 Nakagawa A, Takahashi H, Sato N, Cha BY, Woo JT, Kojima S, Machida Y, Machida CGenomic distribution and functional analyses of putative G-quadruplex-forming sequences in Arabidopsis thaliana. The 21st International Conference on Arabidopsis Research (ICAR 2010) June, (Yokohama) Matsumura Y, Hayashi R, Ohbayashi I, Kojima S, Saez-Vasquez J, Sugiyama M, Machida C, Machida YMutations in ASYMMETRIC LEAVES2 and a DEAD-box RNA helicase required for the rrna processing synergistically impair the establishment of the leaf polarity in Arabidopsis thaliana. The 21st International Conference on Arabidopsis Research (ICAR 2010) June, (Yokohama)

16 76 Nakagawa A, Takahashi H, Sato N, Kojima S, Cha BY, Woo JT, Nagai K, Machida Y, Machida C Genomewide and fuctional analyses of potential G-quadruplex-forming sequences in Arabidopsis thaliana Cold Spring Harbor Asia Symposium. Ooctober, (China) Julio Sáez-VásquezManuel Echeverria ASYMMETRIC LEAVES2AS2 rrna 74 rrna as2 rrna asymmetric leaves asymmetric leaves2 (as2) as1 eal 74 as2 eal eal AS1 AS2 74 AS1, AS2 AS ASYMMETRIC LEAVES1 (AS1),AS2 74 as1, as2

17 asymmetric leaves1, asymmetricleaves2. 74 as1, as2 Julio Saez-VasquezManuel Echeverria ASYMMETRIC LEAVES2 (AS2) rrna ASYMMETRIC LEAVES2 and a DEAD box RNA helicase that functions in processing of ribosomal RNA are involved in the establishment of leaf polarity in Arabidopsis. 33 DEAD box RNA rrna AS1 AS2 52 as1, as2 AS1, AS AS1 AS2 52 AS1, AS EAL 52 EAL ELONGATA3 AS2 52 ELONGATA3 as2-1 Saez-Vasquez JulioEcheverria Manuel ASYMMETRIC LEAVES2 rrna DEAD box RNA helicase 52 DEAD box RNA rrna

18 May. 10,2010LC/MS, (LC/MS),, LC/MS LC/MS June 21-23,2010LC/Q-ToFMS/MS 19,, LC/MS LC/Q-ToFMS/MS June 21-23,2010LC-MS/MS 19, , June 21-23,2010 (2) 19, , June 21-23, , , June 21-23,2010LC/MS 44 19, , LC/MS LC/MS June 21-23,2010LC/MS 45 19, , LC/MS LC/MS

19 79 June 21-23,2010, LC/MS 46, 19, , LC/MS LC/MS June 21-23,2010LC/MS 47 19, , LC/MS LC/MS Suzuki SOct 1-2,2010Trace environmental analysis by LC/MS, Symposium on Advanced Monitoring and Analysis for Toxic Environmental Pollutants, PKNU., VERITAS Hall Pukyong National University, Busan, Korea, LC/MS Oct. 18,2010LC/MS, (LC/MS),, LC/MS LC/MS Suzuki S, Ando T Nov. 3-5,2010 A Study of Chemical Hair Dyes on Human Intake and Release into the Environment by LC/MS, Sookmyung Women's University Centennial Hall, Seoul, Korea, LC/MS Dec. 2,2010 GC-MS LC-MS,,, GC-MS LC-MS Feb. 5,2011,, 45 L-11 45

20 DNA A.Madzvamuse, P.K.Maini ,p.101 (Amago trout, Oncorhynchus masou ishikawae) (Salmonidae) Red spotted masu trout (8 18 ) GABA Inoue K, Ito Y, Hattori Y, Tsutsumiuchi K, Ito S, Hino T, Oka H2010. Efficient purification of xanthomonasin A and B from Monascus yellow colorant by high-speed countercurrent

21 81 chromatography. Jpn. J. Food Chem. Safety 17 (3): HSCCC A B HSCCC /n- / 4/1/5, V/V 10mg HSCCC A B 1.8 / ESI nm 95% HPLC A2.7mg B0.6mg Inoue K, Ikemura A, Tsuruta Y, Watanabe K, Tsutsumiuchi K, Hino T, Oka H2011. Quantification of N-acetyl-seryl-aspartyl-lysyl-proline in hemodialysis patients administered angiotensin converting enzyme inhibitors by stable isotope dilution liquid chromatography tandem mass spectrometry. J. Pharm. Biomed. Anal. 54 (4): / LC/MS/MS N Ac-SDKP Ac-ADKP Ac-SDKP- 13 C6, 15 N2 Ac-ADKP-d7 Ac-SDKP Tsutsumiuchi K, Watanabe Y, Watanabe M, Hibino M, Kambe M, Okajima N, Negishi H, Miwa J, Taniguchi H2011Formation of acrylamide from glucans and asparagine. New Biotechnol. 28: in press. 180 LC/MS/MS AA - AA AA AA HPLC 99 HPLC 2-2-MBA

22 AA 3- (3-MBA) 3-[(2- ) ] (3-CTBA) (KLH) (3-CTBA-KLH) ELISA AA ( -co- ) 59 ( -co- ) ( -co- ) MRI Synthesis of Carbohydrates-Coated Magnetite Nanoparticles Using Click Chemistry. 25th International Carbohydrate Symposium (ICS2010) (Tokyo, Japan). (MRI) -- (1:0.4:0.8) 1,3- (13)--D- (13)--D- (MNP) 1 (13)- -D (13)--D (13)--D FT-IR MNP (SLP ) (13)--D-

23 EXPO 2010 SHANGHAI CHINA (Shanghai, China) AA AA AA AA A A LC/MS N- A 773 A1-6 m/z MS n NMRIR A1-6 (m/z 729) LC-MS/MS Ac-SDKP 35 Ac-SDKP LC-MS/MS Ac-SDKP D- (13)--D- 59 D- 1,3- -2,4,6- -O- --D- (13)--D ( -co- ) 59 (MRI) (RAFT) ( -co- ) HER-2

24 LC-MS/MS Ac-SDKP Ac-ADKP 59 Ac-SDKP ACE ACEI ESA AcSDKP LC-MS/MS Ac-SDKP Ac-ADKP HPLC HPLC AA AA 2-2-MBA NaOH 2-MBA NaOH NaOH 2-MBA AA AA 300 ng/g AA LC/MS GC/MS AA AA a* AA H-D 100 Pt/C Pd/C

25 85 H-D LC-MS/MS Part2 AA AA AA AA AA AA ((S)-AMP (R)-AMP) 2-4 (S)-2-( ) (S)-AMP (R)-AMP ((S)-AMP (R)-AMP) 4 (S)-2-( ) (S)-AMP (R)-AMP Analysis of 4-Methylcatechol-coated Magnetite Nanoparticles by Reactive Pyrolysis-Gas Chromatography. International Conference on Polymer Analysis and Characterization & 15th Symposium on

26 86 Polymer Analysis in Japan. 4- MC-MNPs MC-MNPs Xanthomonasin A B HSCCC Ac-SDKP 131 ACE Ac-SDKP ACE Ac-SDKP Nakagawa H "Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols"SpringerLink, Methods Mol. Biol648, Chapter 9, Ishikawa T, Nakagawa H, Hagiya Y, Nonoguchi N, Miyatake S, Kuroiwa T Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis Advanced in Pharmacological Science, in press Nakagawa H Artesunate und seine Derivate in der Anwendung gegen die HNSCC Zelllinie (UMSCC1) Deutsche Gesellschaft für Hals-Nasen-Ohren -Heilkunde Kopf- und Hals-Chirurgie e.v., Wiesbaden ABCB1 ABCG Selectivity of gefitinib to ABCB1 and ABCG2 with respect to its potential of transport inhibition and restoration of drug resistance in cancer cells 25

27 Genetic polymorphism of human ABCC11 as a determinant of earwax type, axillary osmidrosis, and the risk of breast cancer Detection of the SNP Q141K in the ABCG2 gene by the SmartAmp method: Molecular biological rationale and clinical applications for gout risk prediction ERAD of genetic variants of human ABC transporters ABCG2 and ABCC " ", MOOK, 19, 5, , 7,

28 88 Nakamura R, Nakamura R, Watanabe K, Oka K, Ohta S, Mishima S, Reiko Teshima R Effects of propolis from different areas on mast cell degranulation and identification of the effective

29 89 components in propolis.international Immunopharmacology, 10, (2010) , IV DDS pp pp Minami M, Suzuki M, Hosokawa K, Kondo S, Oka K, Shibata T Preliminary survey of taxonomical problems, pharmacognostical characteristics and chloroplast DNA polymorphisms of the folk medicinal herb Artemisia campestris from the Ryukyu Islands, Japan. Journal of Natural Medicines. 64: Minami M, Aichi M, Ueno K, Terai H, Odawara T, Nasu M, Yokota S, Yonemura S, Suzuki K, Tanaka A Outline and Use of the Experimental Urban SATOYAMA Forest at Chubu University, Aichi Prefecture, Japan. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p.353. Ajioka Y, Aichi M, Ueno K, Terai H, Minami M, Odawara T, Nasu M, Yokota S, Yonemura S Evaluation of environmental factors for the conservation of genetic diversity in Gentiana thunbergii, the SATOYAMA indicator species. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p.343

30 90 15 Yokota S, Odawara T, Nasu M, Yonemura S, Minami M, Aichi M, Ueno K, Terai H Evaluation of Species Diversity and Potential Habitats of the SATOYAMA Indicator Species in Toki-Shonai River Basin. 2nd International Conference of Urban Biodiversity and Design (URBIO2010). p pp Rheum 2010 p Part1 in2010 DEVNET Part2 in2010 DEVNET p.93

31 p D-1pp HSI P118 HSI Watanabe T, Matsunaka T, Nakamura T, Nishimura M, Izutsu Y, Minami M, Watanabe F, Nara, Kakegawa T, Junbo Wang, Liping Zhu Last glacial Holocene geochronology of sediment cores from a high-altitude Tibetan lake based on AMS 14C dating of plant fossils: Implications for paleoenvironmental reconstructionschemical Geology 277:

32 pp Minami M, Tezuka T, Liping Zhu, Nishimura M Survey of vascular flora around Lake Pumayum Co, an alpine lake located in the southeastern Tibetan plateau in China. Journal of Phytogeography and Taxonomy DNA p5 4 DNA p DNA DNA 2010 p.5 DNA rbcl Apodemus 2 DNA 2010 p

33 p HSI 2010 p.8 1 HSI p HSI GIS Tsutsumiuchi K, Watanabe Y, Watanabe M, Hibino M, Kanbe M, Okajima N, Negishi H, Miwa J, Taniguchi H Formation of acrylamide from glucans and asparagine. New Biotechnol. 28: in press. 180 LC/MS/MS AA - AA AA AA Hasegawa K, Miwa J2010Genetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymes. PLoS ONE, 5:e II 4 xrep-1, -2, -3, -4 xrep-1 keap1 WDR-23 - GST

34 94 : , Recommending Hormetic Foods Taught by the Nematode No. 50: Recommending Diet Taught by the Nematode No. 51: 1-5. C. elegans No. 52: 1-4., Hasegawa K, Nonomura Y, Miwa JJune, 2010Genetic characterization of mutants in xenobiotics response pathways. The 4 th East Asia C. elegans Meeting (National Olympics Memorial Youth Center, Tokyo) GST xrep-1 WDR β- GST GST

35 95 Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa JJune, 2010Nematode biosensors to discover functional food ingredients: allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans. The 4 th East Asia C. elegans Meeting (National Olympics Memorial Youth Center, Tokyo). GST UGT GFP II GST Bursaphelenchus xylophilus 60 megabase 10, xrep-3 18 GST xrep-3 xrep-1 GST Acrylamide confers aldicarb resistance on Caenorhabditis elegans via the XREP-1/SKN-1 system 33 II GST XREP-1/XREP C. elegans 55

36 96 C. elegans C. elegans / Baidurah S, Takada S, Shimizu K, Ishida Y, Yamane T, Ohtani H Evaluation of biodegradation behavior of poly(butylene succinate-co-butylene adipate) by reactive pyrolysis-gas

37 97 chromatography in the presence of organic alkali. International Conference on Polymer Analysis and Characterization, Nagoya. (Presentation Award ) μg IC , , Kodama S, Taga A, Yamamoto A, Ito Y, Honda Y, Suzuki K, Yamashita T, Kemmei T, Aizawa S Enantioseparation of DL-isocitric acid by a chiral ligand exchange capillary electrophoresis with Ni(II)D-quinic acid system. (II)-D- DL- Electrophoresis, 31, UV MS 60, ,

38 98 48, HPLC log P LC

39 HPLC HPLC HPLC 59 HPLC EDTA 59 HPLC EDTA EDTA 4 km Kamichatani W, Inoue Y, Saito M, Kobayashi Y, Yamamoto ACounter-ionic effect on the separation of water-soluble compounds applying hydrophilic stationary phase bonded with zwitter-ionic polymer, 2010 Dec., The 4th Japan-China-Korea joint ion analysis symposium, (Gifu,

40 100 Japan) - HPLC Nakashima Y, Suzuki S, Yamazaki M, Inoue Y, Fukatsu Y, Yamamoto A Simultaneous determination of eight ionic and neutral preservatives by inline dialysis-ic coupled with hydrophobic-ion exchange mixed mode column, 2010 Dec., The 4th Japan-China-Korea joint ion analysis symposium, (Gifu, Japan) IC Kemmei T, Kodama S, Fujishima H, Yamamoto A, Inoue Y, Hayakawa KDetermination of EDTA in sea water by solid-phase extraction and high-performance liquid chromatography, 2010 Dec., The 4th Japan-China-Korea joint ion analysis symposium, (Gifu, Japan) HPLC EDTA Suzuki S, Nakashima Y, Yamazaki M, Yamamoto A, Inoue YIon-chromatographic separation of ionic compounds in waste-water using ion exchange columns with different hydrophobicity, 2010 Dec., The 4th Japan-China-Korea joint ion analysis symposium, (Gifu, Japan) Miwa T, Suzuki S, Yamamoto A, Kamichatani W, Inoue Y, Saito MConductivity determination of clopyralid in straw samples applying solid phase extraction with novel halogenated organics selective adsorbent, 2010 Dec., The 4th Japan-China-Korea joint ion analysis symposium, (Gifu, Japan) TOGO

41 HPLC van t Hoff HPLC-UV 131 UV HPLC UV EDTA km 10 m EDTA EDTA

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