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1 2 Vol. 20 No

2 Vol. 20 No

3 ADHD Attention-Deficit/Hyperactivity Disorder Vol. 20 No

4 DSMDiagnostic and Stastical Manual of Mental Disorders,Fourth Edition WHOICD10International Classification of Diseases,Tenth Edition DSM ADHD ICD10 DSM MBDMinimal Brain Dysfunction LDLearning Disabilities MBD Soft Neurological Sign LD Vol. 20 No

5 6 Vol. 20 No

6 ADHD ADHD positive spike WISCRWechsler Inteligent Scale for Child 1025 ITPAIlinois Test of Psycholinguistic Abilities ADHD Vol. 20 No

7 8 Vol. 20 No ADHD carbamazepine haloperidol methylphenidate dextro-amphethaminepemoline 20mg/

8 9 Vol. 20 No ADHD ADHD ADHD 37

9 10 Vol. 20 No ADHD90 ADHD LD FDA 30 40

10 11 Vol. 20 No

11 12 Vol. 20 No Citrobacter Ballerup g/g g/g g/g g/g g/g 20g/g 600g/g

12 13 Vol. 20 No P.zeylanica Peh Mt Fuji

13 Biosphere No.6 14 Vol. 20 No

14 1 QOL QOL QOL coping Vol. 20 No

15 NLP NLPSST NLPFT NLPSSTFT Blankenburg 1982 noncompliant McGhie & Chapman1961 Dawson & Nuechterlin Grossman L & Summers F Vol. 20 No

16 19 Vol. 20 No MOOK 1989 MYW R. P. 1993

17 ICD10F20. X 22 BPRSDIEPSS QOL Johnson DAWObservation no the use of long-acting depot neuroleptic injections in the maintenance therapy of schizophrenia. J. Clin. psychiatry 45 (5) Hogaty GE, Andeson CM, Reiss DJ et al Famity Psychoeducation, Social Skills, and maintenance Chemotherapy in Aftercare Treatment of Schizoprenia. Arch Gen psychiatry p Vol. 20 No

18 ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, T.Theorell 1937 Theorell Vd Kel Theorell Vol. 20 No

19 22 Vol. 20 No Vd Vd t1/2 t1/ Bishoff

20 23 Vol. 20 No HIV mg X tx Xt t

21 t Xt dx/dt Kel dx KelX dt dx/dt dx/dty y=ax X XXe Kelt e Kelt 2,700 Vd XVdC XXe Kelt VdCVdCe Kelt Vd CCe Kelt 1.1 C Ct C 3.0ng/ml X100 e Kelt e Kelt e Kelt e 2.718Kel 24 Vol. 20 No

22 e Kelt CCe Kelt C e Kelt e Kelt C e Kelt e Kelt Fac accumulation factor e Kelt Css.max e Kelt e Kelt e Kelt Css.maxVd Dosee Kel FS S Kel DoseCss.maxVd/FS e Kel F S Css.maxVd FS Css.maxVd/FS Dose DI Dose Css.max Vd F Vol. 20 No

23 Drug Information The 3rd Edition of Michael E. Winters BASIC CLINICAL PHARMACOKINETICS Applied TherapiuticsInc Vol. 20 No

24 ZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ Vol. 20 No

25 2.5 2T T. T 74 1/2T O2 Y. Y 92 L10 1T 25 3T 90100/5060 QOL O. K T 1/2T 1T L20 2T R 2P 3T 100 3P 30 3T 2.5 6T 1T 4T 0.5 1T TTS K. M 70 S T 3T 100 4T T-- 2T Vol. 20 No

26 H. M 83 S 2.0 2P 25 2T 20 2T 2.5 6T 100 3P 100 3T 1.9 K. T MSWPTOT Vol. 20 No

27 32 Vol. 20 No QOL PTOT PT OTMSW QOL ADL QOL

28 Vol. 20 No

29 Zanthoxylum xanthos xylon piperitum Japanease PepperPoivre japonais Zanthoxylum piperitum De Candolle Vol. 20 No

30 Z. piperitum DC. f. inrme Makino 1928 Z. piperitum DC. f. Z. piperitum DC. f. brevispinum Makino Z. armatum DC. var. subtrifoliatum Kitam. Z. alatum Roxb. var. pianispinum Rehd. et E. H. Wils. Z. planispinum Sieb. ex Zucc. m No.1239 Fagara mantchurica Honda Z. schnifolium Sieb. et Zacc. Vol. 20 No

31 g No.1240 Z. bungeanum Maxim. m limonene tt Z. simulans Hance m 10 m Citoronellaldllimonener--Phellandrene GeraniolCitronellol --Sanshoöl --Sanshoöl-- Hydroxy--Sanshoöl-- Hydroxy--Sanshoöl -Sanshoölall-trans-Sanshoöl QuercitrinAfzelinHesperidin 36 Vol. 20 No

32 gg Vol. 20 No

33 27 ADL Vol. 20 No

34 ,80 30, , Vol. 20 No

35 Vol. 20 No

36 NPO 12) 12 non-profit-organizationimidas 98 NPO NPONPO 42 Vol. 20 No

37 PL 1 Clinical Pharmacy Vol. 20 No

38 Vol. 20 No

39 45 Vol. 20 No QOL

40 Vol. 20 No

41 Vol.20, No.5, Vol.31, No.10, Vol.46, No.10, Vol.19, No.9, Vol. 20 No

42 From Kuraya Drug Information Center 48 Vol. 20 No

43 Vol. 20 No

44 50 Vol. 20 No

45 Vol. 20 No

46 52 Vol. 20 No

47 Vol. 20 No

48 ^ 10/ 10/ , FAX /17 11/28 10,000 1 Vol. 20 No

49 56 Vol. 20 No

50 57 Vol. 20 No

51 !! 30 TO SEE IS TO BELIVE 58 Vol. 20 No

52 E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D E F G A B C D Vol. 20 No

53 62 Vol. 20 No NaN3 LDL046mg/kg LDL030mg/kg LDL035mg/kg LD50 18mg/kg LDL012mg/kg mg mg/kg mg 15 NaNa CNKCNNaCN HCNLDL00.57mg/kg 50100mg KCN150200mg NaCN200300mg KCNNaCNHCN 5, % 1530/ Na Na10ml 25Na50ml10 25KGNa

54 63 Vol. 20 No mg/kg 10 Na125ml10 Na 10 As4AsO3AsCl3AsH3 AsO3LD501.43mg/kg 60120mg AsH3TDL00.11mgAs/kg SH Mg30g 200mlP BAL100mg/A 2.5mg/kg10Na10ml g Na5g LDL0 LD50 50 TDL0

55 64 Vol. 20 No mg 30mg

56 65 Vol. 20 No , Q&A flecainidflecainido 14flubiprofenflurbiprofen FU UF methimazolethiamazole

57 Vol. 20 No ADHD ,000 YMCA YMCA JR

ADHD LD ITPA K ABC DSM ADHD LD MBD WISC K ABC ITPA 62

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