Juntendo Medical Journal

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1 The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical Co. LTD. Saitama, Japan

2 Fig.-1 Minoxidil Fig.-2 Hair growing effect of Minoxidil in C3 H mice

7 26)Galbraith, G. P. et al.: Int. J. Dermatol, 24: 249, )Fiedler-Weiss, V.C. etal.: Brit. J. Dermatol, 117: 756, )Broulik, P.D. et al.: Pharmacolgy, 36: 321, )Nuck, B.A. at al.: Ach. Dermatol, 123 : 59, )McCall, J.M. at al.: J. Med. Chem, 26: 1791, )DeVillez, R.L.: Dermatologic Clinics, 8 : 367, Uno, H et al.: J. Am. Acad. Dermatol, 16 : 657, )Matias, J.R. et al.: Arch. Dermatol. Res., 28 : 247, )Matias, J.R. at al.: Clinics in Dermatol, 6 : 169, )Takeshita at al.: The Molecular and Structual Biology of Hair, (Arlington) p-17, (1991). 6)Kligman, L. H., Clinics in Dermatol, 6 : 163, )Gobe, G.C. at al.: Acta Derm. Venereol, 69 : 190, )Buhl, A.E. at al.: Laboratory Investigation, 62: 104, )Picascia, D.D. at al.: Arch Dermatol, 123 : 1432, )Prost, Y. de, et al.: Lancet, 11: 803, )Mori, O. at al.: J. Dermatol, 17: 276, )Frienkel, R.K. at al.: J. Invest. Dermatol, 92 : 430 (abstract), Philpott, M.P. et al.: J. Cell Science, 97: 463, )Buhl, A.E. at al.: J. Invest. Dermatol, 92: 315, )Philpott, M.P. at al.: J. Cell Sci, 97 : 463, )Katsuoka, K at al.: Arch Dermatol Res.279 : 247, )Baden, H.P. at al.: J. Invest. Dermat, 81: 558, )Kubilus, J. et al.: J. Am. Acad. Dermatol. 16: 648, )Cohen, R.L. at al.: J. Invest. Dermatol. 82 : 90, )Murad, S.I,: J. Biol. Chem. 25: 11973, )Norris, W. D. at al.: Cell, Biol. Int. Rep. 13 : 555, )Wester, R.C. at al.: J. Invest. Dermatol. 82: 515, )Hirkaler, G.M. at al.: J. Pharmacol. Method, 21: 127, )DeBoer, E.M. at al.: Acta Derm, Venereol, 68: 271, )Chambers, D.A. at al.: Brit. J. Dermatol. 111: 114, )Johnson, G.A.: Biochem. Pharm, 31: 2949, )Buhl, A.E. at al.: J. Invest. Dermatol, 95: 553, )Johnson, G.A. et al.: Clinica Chimica Acta, )Johnson, G.A. at al.: Biochem, Pharmacol, 31: 2949, )Dooley, T.P. et al.: J. Invest. Dermatol, 96: 65, )Hamamoto, T. at al.: Res. Commun. Chem. Pathol. Pharm, 66: 33, )Johnson, G.A. at al.: J. Invest. Dermatol, IM,FP 38)Baker, C.A. at al.: J. Invest. Dermatol, 96: 576, )Dooley. T.P. at al.: J. Invest. Dermatol, 96: 65, )Oliver, R.F.: J. Embryol. Exptl. Morph. 1,5: 331, )Diani, A.R. et al.: The molecular and structural biology of hair growth (Arlington) )Zelei, B.V. at al.: Cell Tissue Res, 262: 407, )Meisheri, K.D. at al.: J. Pharmacol. Exptl. Therap, 215: 751, )Leblanc, N. at al.: Circulation Res, 65: 1102, )Winquist, R.J. at al.: J. Pharmacol. Exptl. Therap, 218: 149, )Meisheri, K.O. et al.: J. Pharmacol. Exptl. Therap, 258 : 1091, )Kvedar, J.C. et al.: Biochem. Pharmacol, 37: 867, )Tasijian A.H. at al.: Endocrinology, 123: 969, )Hamphrey, S. J. et al.: J. Cardiovasc. Pharmacol, 6 : 979, )Novak, E. at al.: Internat. J. Dermatol, 24: 82, )Meisheri, J.P. et al.: J. Pharm. Exptl. Ther, 258: 1091, )Newgreen, D.T. at al.: Br. J. Pharmacol, 100: 605, )Groppi, J. at al.: J. Invest. Dermatol, 94: 532, )Godwood, R.C. etal.: Ann. Rep. Med. Chem, 24: 187, )Harmon, J. et al.: J. Invest. Dermatol, 94: 533, 1990

日本皮膚科学会雑誌第122巻第2号

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