Size: px
Start display at page:

Download ""

Transcription

1

2

3

4

5

6

7 1) van Meer, G., Op den Kamp, J. A.: J. Cell. Biochem., 19, ) 2) Gaffet, P., Bettache, N., Bienvenue, A.: Biochemistry, 34, (1995) 3) Sims, P. J., Wiedmer, T.: Thromb. Haemost., 86, (2001) 4) Tang, X., Halleck, M. S., Schlegel, R. A., Williamson, P. : Science, 272, (1996) 5) Pomorski, T. et al. : Mol. Biol. Cell, 14, (2003) 6) Farge, E., Ojcius, D. M., Subtil, A., Dautry-Varsat, A.: Am. J. Physiol., 276, C (1999) 7) Emoto, K. et al.: J. Biol. Chem., 280, (2005) 8) Kato, U. et al.: J. Biol. Chem., 277, (2002) 9) Chen, C. et al.: Cell, 47, (1986) 10) Fojo, A. T. et al.: Proc. Natl. Acad. Sci. USA, 84, (1987) 11) Ueda, K. et al.: J. Biol. Chem., 262, (1987) 12) Smit, J. J. et al.: Cell, 75, (1993) 13) Deleuze, J. F. et al. : Hepatology, 23, (1996) 14) Smith, A. J. et al.: FEBS Lett., 354, (1994) 15) van Helvoort, A. et al.: Cell, 87, (1996) 16) Bosch,1. et al.: Biochemistry, 36, (1997) 17) Kalin, N., Fernandes, J., Hrafnsdottir, S., van Meer, G. : J. Biol. Chem., 279, (2004) 18) Brooks-Wilson, A. et al. : Nature Genet., 22, (1999) 19) Tanaka, A. R. et al.: Biochem. Biophys. Res. Commun., 283, (2001) 20) Wang, N., Silver, D., Costet, P., Tall, A. : J. Biol. Chem., 275, (2000)

8 21) Zhang, W., Asztalos, B., Roheim, P. S., Wong, L.: J. Lipid Res., 39, (1998) 22) Fielding, P. E. et al. : Biochemistry, 39, (2000) 23) Wang, N., Silver, D. L., Thiele, C., Tall, A. R. : J. Biol. Chem., 276, (2001) 24) Hamon, Y. et al.: Nature Cell Biol., 2, (2000) 25) Chambenoit, 0. et al.: J. Biol. Chem., 276, (2001) 26) Alder-Baerens, N. et al.: J. Biol. Chem., 280, (2005) 27) Ikeda, Y. et al. : Biochem. Biophys. Res. Commun., 311, (2003) 28) Toda, Y. et al.: Pathol. Int., 55, (2005) 29) Hayashi, M. et al.: J. Lipid Res., 46, (2005) 30) Wang, N. et al.: J. Biol. Chem., 278, (2003) 31) Shulenin, S. et al.: N. Engl. J. Med., 350, (2004) 32) Yamano, G. et al.: FEBS Lett., 508, (2001) 33) Nagata, K. et al.: Biochem. Biophys. Res. Commun., 324, (2004) 34) Akiyama, M. et al. : J. Clin. Invest., 115, (2005) 35) Wang, N. et al. : Proc. Natl. Acad. Sci. USA, 101, (2004) 36) Kennedy, M. A. et al.: Cell Metab., 1, (2005) 37) Berge, K. E. et al. : Science, 290, (2000) 38) Yu, L. et al.: J. Biol. Chem., 278, (2003)

Various function and toxicity of iron Key words 1) Hentze, M. W. et al: Cell, 117, 285-297 (2004) 2) Ganz, T.: Blood, 102, 783-788 (2003) 3) Nemeth, E. et al.: Science, 306, 2090-2093 (2004) 4) Hentze,

More information

VOL33NO.3/2010 A B A B p-erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 Erk1/2 Time (min) 0 1 2 5 10 15 30 60 90 120 p-vasp VASP C D enos/gapdh x-fold vs sham 2.0 1.5 1.0 0.5 * 0 ANP (-) (+) (-)

More information

2007050781......_.L.O...z.W

2007050781......_.L.O...z.W a s d f g a s d f g h j k l 0 in vitro in vivo in vitro in vivo in vivo in vivo in vitro Metabolism Metabolism Endocr Endocr Endocrinol Ann NYA cad Sci J clin Endocr Metab

More information

Kazuo Emoto, Masato Umeda, E-mail : emoto@rinshoken.or.jp pliakov, 0., De Camilli, P.: Neuron, 24, 143-154 (1999) 8) Takei, K., Haucke, V., Slepnev, V., Farsad, K., Salazar, M., Chen, H., De Camilli,

More information

表1.eps

表1.eps Vol.1 C ontents 1 2 cell-free EMBO J Proc. Natl. Acad. Sci. USA NatureEMBO J 3 RNA NatureEMBO J Nature EMBO J 4 5 HCV HCV HCV HCV RNA HCV in situ 6 7 8 Nat Struct Mol Biol J Biol Chem Nat Commun J Virol

More information

drug development Toshimi Michigami, E-mail : michigami@mch.pref.osaka.jp Keiichi Ozono, E-mail : keioz@ped.med.osaka-u.ac.jp The progress in the research on vitamin D 1) McCollum, E. V. et al.:

More information

Novel chemical mediators in the resolution of inflammation Charles N. Serhan Key words E-mail : marita@nih.go.jp Charles N. Serhan Brigham & Women's Hospital/Harvard Medical School 1) Serhan, C. N.,

More information

Kazumitsu Ueda, [Department of Applied Life Science, Kyoto University Graduate School of Agriculture, Kitashirakawa, Sakyo-ku, Kyoto 606-01, Japan] Molecular Mechanisms for Drug Transport by MDR1/P-glycoprotein

More information

Correlation between molecular evolution of P450s and evolution of plant secondary metabolism Masaharu Mizutani E-mail : mizutani@scl.kyoto-u.ac.jp URL : http://biofun.kuicr.kyoto-u.ac.jp/index-j.html 13)

More information

Review Fumio Imamoto1, Takefumi Sone1, Kazuhide Yahata1, Yukari Sasaki1, Masatoshi Takagi2, Kazuhiro Maeshima2, Naoko 25) Dong, W. K. et al.: Gene, 91, 217-223 (1990) 26) Masatsugu, T. et al.:

More information

10中西_他.indd

10中西_他.indd Streptomyces mobaraensis N N N Sm b Sm N N Sm Sm Sm ' ' Sm Sm ak K k K bk k K Sm Sm a b S. mobaraensis a b a b Sm b b bb b b Sm Sm S. lividans ab Sm ab Sm ab ab ab ab SmSm S. lividansab S. lividans ab

More information

Florigen in rice Key words Shojiro Tamaki, Ko Shimamoto E-mail : s-tamaki@bs.naist.jp, simamoto@bs.naist.jp URL : http://bsw3.naist.jp/simamoto/simaoto.html 1) Thomas, B., Vince-prue, D.: Photoperiodism

More information

tary adenylate cyclase activating polypeptide ; PA-

tary adenylate cyclase activating polypeptide ; PA- Conformation of a peptide ligand bound to its G-protein coupled receptor and its implication for ligand transportation tary adenylate cyclase activating polypeptide ; PA- molecular biology (ed. Rich,

More information

Kazumitsu Ueda, E-mail : uedak@kais.kyoto-u.ac.jp http : //cseika-1, kais.kyoto-u.ac.j p Molecular mechanism of multidrug transporter MDR I : ABC in host-defense machinery 32P-ATP 1) Chen, C., Chin,

More information

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey

The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Database Center for Life Science Online Service Key words Shigey The function and structure of NAD kinase: the key enzyme for biosynthesis of NADP (H) Key words Shigeyuki Kawai, Chikako Fukuda, Kousaku Murata E-mail : kawais@kais.kyoto-u.ac.jp, chikakko@kais.kyotou.ac.jp,

More information

2

2 1999 No. 5 CHAPERONE NEWSLETTER CONTENTS 2 3 4 JEM JEM JEM, SEC, SCJ JEM JEM SCJ jem, scj 5 in vitro S. cerevisiae 6 K 7 in vitro Cell Mol. Cell in vitro 8 9 E. coli E. coli 10 in vitro ssc - b 11 in vivo

More information

Database Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*,

Database Center for Life Science Online Service (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, (http : // taxonomy.zoology.gla.ac.uk/rod/treeview.html) Takaaki Abe, Michiaki Unno*, Tohru Onogawa*, E mail : takaabe@mail.cc.tohoku.ac.jp Taro Tokui, Molecular identification of organic anion transporter

More information

Short Review Hidenori Takagi, Fumio Takaiwa, E-mail : takaiwa@nias.affrc.go.jp 13) Hirahara, K. et al. : J. Allergy Clin. Immunol., 102, 961-967 (1998) 14) Takagi, H. et al.: Proc. Natl. Acad. Sci.

More information

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap

Database Center for Life Science Online Service Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sap Miho Shimizu, [Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060, Japan] Molecular Basis of Triplet Repeat Diseases : Genetic Instabillity and Unusual DNA

More information

.i...j...[.X8-2

.i...j...[.X8-2 Vol. 8 No.2 Nov. 2007 1 2 4 12 20 37 45 54 56 62 1 2 3 4 5 7 6 8 9 10 11 13 12 15 14 17 16 19 18 21 20 Hatena 23 22 Oidiodendron Oidiodendron 25 24 Monosiga ovata Monosiga 27 26 Toxoplasma gondii 29 28

More information

4) H. Takayama et al.: J. Med. Chem., 45, 1949 (2002). 5) H. Takayama et al.: J. Am. Chem. Soc., 112, 8635 (2000). 6) H. Takayama et al.: Tetrahedron Lett., 42, 2995 (2001). 9) M. Kitajima et al: Chem.

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service Database Center for Life Science Online Service SMN (Survival

More information

日本皮膚科学会雑誌第121巻第11号

日本皮膚科学会雑誌第121巻第11号 β Clin Rheumatol Arthritis Rheum Am J Cardiol J Rheumatol J Rheumatol Arthritis Rheum Arthritis Rheum Arthritis Rheum Rheumatology Oxford Rheumatology Oxford Br J Dermatol Arch Dermatol Ann Rheum Dis

More information

Bio-No.57/3....

Bio-No.57/3.... 2004. MAR. 3No.57 http://www.wako-chem.co.jp C O N T E N T S 2 Wako Bio Window No.57 MAR.2004 l l l l wako wako l l mmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmmm Wako Bio Window No.57 MAR.2004 3 4 Wako Bio Window

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 2) Shin, S. I., Fredman, V. H., Risser, P., Pol lack,r.: Proc. Natl. Acad. Sci. USA, 72, 4435-4439 (1975) 3) Marquardt, H., Todaro, G. J.: J. Biol. Chem., 256, 6859-6865 (1981) 4) Dicker, P., Pohjanpelto,

More information

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal

Database Center for Life Science Online Service Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal Natronobacterium pharaonis Crystal structure of phoborhodopsin : Mechanisms of color tuning and signal transduction Needleman, R., Lanyi, J. K. : Science, 269,73-75 (1995) 3) Bogomolni, R. A., Stoeckenius,

More information

untitled

untitled Fig.1 t O O N,N p n J J J J J t J J J J J J J J J J J t t J J J J J J J J J p Fig.2 p t Fig.3 Fig.4 synanti p Table1 Table2t Table2 synanti antisyn synanti synanti Fig.5 syn anti anti Fig.6 Table3 Table4

More information

肺癌第50巻第4号

肺癌第50巻第4号 1 Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan; 2 Department of Thoracic Surgery, Aichi Cancer Center, Japan;

More information

Database Center for Life Science Online Service Vol.48 No.16 (2003)

Database Center for Life Science Online Service Vol.48 No.16 (2003) Database Center for Life Science Online Service Key words Kikuya Kato, E-mail : kkato@bs.aist-nara. ac.jp http://love2.aist-nara.ac.jp Shin Ishii, E-mail : ishii@is.aist-nara.ac.jp http://hawaii.aist-nara.

More information

Database Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate

Database Center for Life Science Online Service Signal transduction of growth factor mediated by heparin heparan sulfate Signal transduction of growth factor mediated by heparin heparan sulfate 1) Zhu. X.. Komiya, H., Chirino, A.. Faham. S.. Fox, G. M., Arakawa, T., Hsu, B.T., Rees, D. C.: Science. 251, 90-93 (1991)

More information

Database Center for Life Science Online Service Structure and function of nitric oxide synthases

Database Center for Life Science Online Service Structure and function of nitric oxide synthases Structure and function of nitric oxide synthases 3) Furchgott, R. F., Zawadzki, J. V. : Nature, 288,373-376 (1980) 4) Palmer, R. M., Ferrige, A. G., Moncada, S.: Nature, 327,524-5260987) 5) Alderton,

More information

Minamiooya, Machida, Tokyo 194, Japan] RNA World, A Key Step in the Origin of Life : Inspection from the View Point of Biological Evolution 1) Crick, F. H. C.: Sym. Soc. Exp. Biol., 12, 548-555

More information

64) M.L. Gefter, R.L. Russell: J. Mol. Biol., 39, 145 (1969) 65) F. Harada, F. Kimura and S. Nishimura: Biochim. Biophys. Acta., 182, 590 (1969) 65a) F.H.C. Crick: J. Mol, Biol., 19, 548 (1966); M. Nirenberg

More information

Database Center for Life Science Online Service Chiharu Ueguchi, Molecular mechanism and biological function of t

Database Center for Life Science Online Service Chiharu Ueguchi,   Molecular mechanism and biological function of t Chiharu Ueguchi, E-mail : cueguchi@agr.nagoya-u.ac.jp Molecular mechanism and biological function of the cytokinin signal tansduction pathway 1) Miller, C. 0., Skoog, F., von Saltza, M. H., Strong,

More information

Teru Ogura, Tomoko Yamada-Inagawa, E-mail : ogura@gpo.kumamotou.ac.jp AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins 29) Braun, S.,

More information

[Department of Pediatrics, Gifu University School Clinical. Pathological and Biochemical Abnormality in peroxisomal Disorders 1) Goldfischer, S., Moore, C. L., Johnson, A. B., Spiro, A. J., Valsamis,

More information

Review Column 1) Extavour, C. G., Akam, M. : Development, 130, 5869-5884 (2003) 2) Saitou, M. et al.: Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358,1363-1370(2003) 3) Eddy, E. M. : Int. Rev.

More information

Spatio-temporal regulation of ERK1/2 MAP kinase 20) Murphy, L. 0., MacKeigan, J. P., Blenis, J.: Mol. Cell. Biol., 24, 144-153 (2004) 21) Harada, T., Morooka, T., Ogawa, S., Nishida, E.: Nature Cell

More information

2007 Vol.56 No.6 総説 丸山浩樹

2007 Vol.56 No.6 総説 丸山浩樹 Reprinted from RADIOISOTOPES, Vol.56,.6 June 2007 Japan Radioisotope Association http : //www.jrias.or.jp/ α β α β ε m z α µ µ α m z m z µ µ Curr. Opin. Biotechnol J. Proteome Res Rapid Commun. Mass

More information

The Heart Healthy Tocotrienol Complex Tocomin SupraBio

The Heart Healthy Tocotrienol Complex Tocomin SupraBio The Heart Healthy Tocotrienol Complex Tocomin SupraBio The Heart Healthy Tocotrienol Complex Tocomin SupraBio 1. Fact Sheet No. 317; World Health Organization (WHO), 2007 2. LLOYD-JONES D. et al. Circulation

More information

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing

Database Center for Life Science Online Service Discovery, analysis and chemical mechanism of protein splicing Discovery, analysis and chemical mechanism of protein splicing VMA1 VMA1 2) Anraku, Y.: Genes to Cells, 2, 359-367 (1997) 3) Perler, F. B.: Cell, 92,1-4 (1998) 4) Perler, F. B.: Trends Biochem.

More information

5200) [Department of Biochemistry, Miyazaki Medical College, Kihara, Kiyotake-cho, Miyazaki 889-16, Japan] Natriuretic Peptide Family: ANP and BNP 1) de Bold, A. J.: Science, 230, 767-770 (1985)

More information

Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo

Generation of neural cells from embryonic stem cells Database Center for Life Science Online Service Takuya Yohei Okada Takahito Hideyuki Shimazaki Yo Generation of neural cells from embryonic stem cells Takuya Yohei Okada Takahito Hideyuki Shimazaki Yoshizaki* Okano McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence

More information

(Sinorhizobium melitoti )

(Sinorhizobium melitoti ) ID ID INDE- TERMINATE (ID) /JST CREST E-mail : masayosicbiol. s.u-tokyo.ac.j p Systemic regulatory system sustaining symbiosis and organ development in legume (Sinorhizobium melitoti ) astray sunn nts

More information

437“ƒ

437“ƒ et al., et al., et al., et al., et al., et al., 2 et al., et al., et al., Lancet Pharmacol Res. et al. Jpn J Cancer Res. et al. Jpn J Cancer Res. et al. Tohoku J Exp Med. et al. Jpn Circ J. et al. Cancer

More information

Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara,

Database Center for Life Science Online Service Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara, Masami Horikoshi, Ryosuke Himukai, Takashi Kuzuhara, E-mail : horikosh@iam.u-tokyo.ac.jp http://www.iam.u-tokyo.ac.jp/homasami/ 1) Jacob, F., Monod, J. : J. Mol. Biol., 3, 318-356 (1961) 2) Ptashne,

More information

第6号-2/8)最前線(大矢)

第6号-2/8)最前線(大矢) 最前線 免疫疾患における創薬標的としてのカリウムチャネル 大矢 進 Susumu OHYA 京都薬科大学薬理学分野教授 異なる経路を辿る 1つは マイトジェンシグナル 1 はじめに を活性化し 細胞増殖が促進されるシグナル伝達経 路 図1A 右 であり もう1つはカスパーゼやエ 神 経 筋 の よ う な 興 奮 性 細 胞 で は カ リ ウ ム ンドヌクレアーゼ活性を上昇させ アポトーシスが K

More information

Biology of spermatogenesis and spermatozoa in mammals. Biophys. Biochem. Cytol. Arch. Biochem. Biophys. Anat. Rec. Biol. Reprod. Mol. Hum. Reprod. Biol. Reprod. Reprod. Biol. Endocrinol. Aust. J. Zool.

More information

1) Y. Hatefi: Annu. Rev. Biochem., 54, 1015 (1985). 2) H. Weiss, T. Friedrich, G. Hofhaus & D. Preis: Eur. 4) M. Yamaguchi & Y. Hatefi: Biochemistry, 32, 1935 (1993). 5) K. Leonard, H. Haiker & H. Weiss:

More information

Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge

Review Database Center for Life Science Online Service Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge Review Masanori Mishima, p Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge E-mail : m.mishima @gurdon.cam.ac.uk http://www.gurdon.cam.ac.uk/groups/mishima.html Cytokinesis :

More information

色覚(初組4).pm

色覚(初組4).pm 733 3 1 520 1 8 4 0.2500 1 30012 1 AB 3 22 3 1 2 http://www.nig.ac.jp/labs/devgen/mou.html 734 1.1 360nm 830nm 380nm 780nm 540nm 580nm 660nm 540nm 660nm Log relative corneal sensitivity 0 1 2 400 500 600

More information

2009 Aida et al. Caries Res 2006;40 2000 100 % 78.7 88.0 96.6 98.8 98.8 98.8 100.0 100.0 100 75 69.4 50 75.3 74.8 73.3 73.1 73.0 72.4 71.8 71.7 51.7 40.2 69.4 68.8 73.6 25 22.3 32.8 21.9 22.9 22.1

More information

Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati

Database Center for Life Science Online Service School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferati School of Medicine, Seiryo-machi, Sendai 980, Japan] Biological Role of NDP-kinase in Cell Proliferation and Activation Mechanism of GTP Binding Proteins by the Enzyme 3) Nishizuka, Y.: Nature,

More information

あまり関係ないことまで述べられていないか?( 混乱の元になるので良くない ) 引用の仕方は首尾一貫しているか?( 複数入り混じるのは良くないと思う ) 悪い例 : 先行研究においては~という結果が得られた(Tsugame et al., 2014) 一方 Tsugamo らは~という結果も得ている

あまり関係ないことまで述べられていないか?( 混乱の元になるので良くない ) 引用の仕方は首尾一貫しているか?( 複数入り混じるのは良くないと思う ) 悪い例 : 先行研究においては~という結果が得られた(Tsugame et al., 2014) 一方 Tsugamo らは~という結果も得ている 論文についての覚え書き 2016 年 9 月 14 日改訂 津釜大侑 研究を進めていく上で論文を読むのは最も基本的で重要な作業です 論文を読む上で気を 付けると良いと思われることについて以下に挙げます 論文の種類 Research article 実験解析の結果を載せる 論文というと普通これを指す ゼミではこれを扱います Short communication 量は多くないが重要性が高いデータを迅速に公表するためのもの

More information

感 染 症 にお ける 細 胞 貪 食 の 役 割:宿 主と微生物の攻防 食細胞による微生物の取 り込みと殺菌 水上令子 武谷 立 住本英樹 細 菌や真菌が食細胞内 に取 り込 まれ るときに は,ま ず細胞表面 の受 容体 によ って微生 物が認 識 される.こ の食 作用受容体の下流で起 こるシグナル伝達 によ り,微 生物 を内部 に取 り込 んだ 食 胞 が細 胞内に形成される.食 胞は成熟の過程

More information

Juntendo Medical Journal

Juntendo Medical Journal The hair growth effect of minoxidil Susumu OTOMO, Ph. D. Key words : minoxidil, minoxidil sulfate, hair growth, K+-channel opener, male pattern baldness Dept. of Pharmacology, Research Center Taisho Pharmaceutical

More information

宿 主 特 異 性 を決 定 す る た め に非 常 に大 き な 役 割 を も った 割 を 演 じ る こ と に な る.ま 物 質 で あ る こ とは 間 違 い な い.ま た,Nod る菌 体 外 多 糖 の生 成 が菌 の 感 染 に 関与 して い る こ と も知 factorは マ メ科 植 物 根 細 胞 の 根 粒 形成 に 関 す る 遺 伝 子(nodulin gene)を

More information

1) Ogawa, H., Lazarus, G. S., Hopsu-Havu, K.: The Biological Role of Proteinases and their Inhibitors in Skin, Univ. Tokyo Press (1985) 2) Sottrup-Jensen, L., Stepanik, T. M., Kristen sen,t., Wierzbicki,

More information

Vol.53 No. 11 (2008) 1327

Vol.53 No. 11 (2008) 1327 Molecules that regulate morphology of the plasma membrane Shiro Suetsugu, Kazunori Takano E-mail : suetsugu@iam.u-tokyo.ac.jp 1326 Vol.53 No. 11 (2008) Vol.53 No. 11 (2008) 1327 1328 Vol.53 No. 11 (2008)

More information

Database Center for Life Science Online Service [Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome,

Database Center for Life Science Online Service [Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome, [Department of Molecular Physiology, The Tokyo Metropolitan Institute of Medical Science, Honkomagome, Bunkyo-ku, Tokyo 113, Japan] [Graduate School of Agricultral Bioscien- ces, The University of Tokyo,

More information

日本皮膚科学会雑誌第122巻第2号

日本皮膚科学会雑誌第122巻第2号 J Dermatol Sci Vitam Horm NEnglJMed Lancet J Clin Invest Antitoxid Redox Signal Diabetes Metab Res Rev Diabetes Care Diabet Med Diabetes care Diabetes Care J Foot Ankle Surg Wound Repair Regen Lancet Foot

More information

Short Review E-mail : kuwata@cc.gifu-u.ac.jp Structural medicine and structure-based drug design for prion diseases 2) Anfinsen, C. B.: Harvey Lect., 61, 95-116 (1967) 3) Carrel, R. W., Lomas, D. A.

More information

本文/YA9255F

本文/YA9255F pp. ATP ε ATP ATP ATP ε Bacillus PS ATP ATP H H µ H ATP ATP ADP µ H ATP FoF -ATP FoF -ATP µ H H ADP ATP H Na On the regulatory role of the epsilon subunit in ATP synthase Yasuyuki Kato-Yamada Department

More information

E-mail : tmatsumo@house.rbc.kyoto-u.ac.jp htm Spindle checkpoint : Cell cycle regulation by a signal emitted from kinetochores http://www.rbc.kyoto-u.ac.jp/radiation_system/m-index. 19) Yao, X., Abrieu,

More information

Stress-responsive MAP kinases 15) Lu, H. T., Yang, D. D., Wysk, M., Gatti, E., Mellman, I., Davis, R. J., Flavell, R. A. : EMBO J., 18,1845-1857 (1999) 16) Lu, B., Yu, H., Chow, C., Li, B., Zheng,

More information

1) P. Nurse, P. Thuriaux & K. Nasmyth: Mol. Gen. Genet., 145, 167 (1976). 2) R. Ohi, C. McCollum, B. Hirani, G.J. Den Hasse, X. Zhang, J.D. Burke, K. Turner & K.L. Gould: EMBO J., 13, 471 (1994). 3) T.

More information

ü β 93

ü β 93 Amyloid Fibril Formation and Protein Science Yuji GOTO Institute for Protein Research, Osaka University E-mail: ygoto@protein.osaka-u.ac.jp Abstract: Amyloid fibrils have been a critical subject in recent

More information

2) Pytela, R., Pierschbacher, M. D., Ruoslahti, E.: Cell, 40, 191-198 (1985) 3 z Thunberg, L., Backstrom, G., Lindahl, U.: Carbohydr. Res., 100, 393-410 (1982) 4) Petitou, M.: Nelle. Rev. Fr. Hematol.,

More information

Establishment and progress of Sendai virus engineering 2) Schnell, M. J., Mebatsion, T., Conzelmann, K.-K.: EMBO J., 13,4195-4203(1994) 3) Kato, A. et al.: Genes Cells, 1, 569-579 (1996) 4) Nagai,

More information

本文/YA9255C

本文/YA9255C pp. E- -SH X in vitro in vivo -SH Structure-based drug development and medical biological application of cathepsin specific inhibitors Nobuhiko Katunuma Institute for Health Sciences, Tokushima Bunri University,Nishihamabouji,

More information

1) Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., Coyle, J.T.: Neuron, 2, 1547-1558 (1989) 2) Pellegrini-Giampietro, D.E., Cherici, G., Ale siani,m., Carla, V., Moroni, F.: J. Neuro science,10,

More information

Tomohiro Terada, Ken-ichi Inui, Peptide transporter family situ 1) Matthews, D.M. : Physiol. Rev., 55, 537-608(1975) 2) Ganapathy, V.. Leibach, F.H.: Am. J. Physiol. Gastro intest. Liver Physiol.,

More information

Database Center for Life Science Online Service Natuo Komoto, jp Silkworm mutants

Database Center for Life Science Online Service Natuo Komoto,   jp   Silkworm mutants Natuo Komoto, E-mail : natuo@affrc.go. jp http://cse.nias.affrc.go.jp/natuo/index.htm Silkworm mutants whose deficiency of epidermal orate granules causes translucent larval skin phenotypes 図3 カイ コ幼 虫

More information

3) Z. Nambu: in preparation (1971). 4) N. P. Wilkins & J. D. Iles: Comp. Biochem. Physiol., 17, 1141 (1966). 5) V. M. Ingram: Nature, 235, 338 (1972). Bacillus cereus var. mycoides, Bacillus thuringiensis

More information

THOMSON REUTERS PRESENTATION TEMPLATE

THOMSON REUTERS  PRESENTATION TEMPLATE JCRW の利用方法について インパクトファクター及びその他の指標について JCRW の利用方法について インパクトファクターとは? 2009 年 10 月 8 日 トムソンロイター 甲斐真佐美 masami.kai@thomsonreuters.com TEL: 03-5218-6507 この講習会の目的 Journal Citation Reports の基本操作を覚える インパクトファクターの作られ方とその意味を正しく理解する

More information

…h…L…–…†…fi…g1

…h…L…–…†…fi…g1 21 1326 1328 2002 22 4375 4377 2003 34 6 848 849 2005 9 10 15 1067 1070 1996 49 133 166 2003 1 2 2 3 4 4 1 3 23 311 313 2004 5 1 118 7604 7607 1996 15 1 33 6627 6629 2000 12 649 155 167 2003 76 23 7007

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 10) Shinagawa, H., Kato, T., Ise, T., Makino, K., Acad. Sci. USA, 82, 4336-4340 (1985) Sci. USA, 85, 1811-1815 (1988) 19 zwoodgate, R., Rajagopalan, M., Lu, C., Echols, H.: Proc. Natl. Acad. Sci. USA,

More information

untitled

untitled 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Int J Radiat Oncol Biol Phys 49 Cancer 101 Int J Radiat Oncol Biol Phys 60 Chest 124 Int J Radiat Oncol Biol Phys 56 Int J Radiat Oncol Biol Phys 49 Chest 124 Int J

More information

432..

432.. et al., et al., et al., år är ön Nature Rep. int. Whal. Commn Mar. Mamm. Sci ICES Journal of Marine Science år år önlobodon carcinophaguscanadian Journal of Fisheries and Aquatic Sciences Rep. int.

More information

日本皮膚科学会雑誌第122巻第7号

日本皮膚科学会雑誌第122巻第7号 Br J Dermatol NEnglJ Med 尋常性白斑診療ガイドライン 図 1 先天性白斑 白皮症の病型分類 図 2 後天性白斑 白皮症の病型分類 の尋常性白斑患者で家系内発症がみられることより 3 5 れらの合併が染色体 17p13 における一塩基多型に起 非分節 因し その候補遺伝子の一つが自然免疫に重要とされ 型に含まれる汎発型には甲状腺に対する抗サイログロ る NALP1 遺伝子であると報告している6

More information

fpj

fpj 特集生体機能の多階層的理解と創薬研究への応用 Folia Pharmacol. Jpn. 147 要約 :Pi 3 CKD CKD FGF Nampt 1. はじめに chronic kidney disease CKD CKD CKD FGF,, CKD 辰巳佐和子, 宮本賢一 2. リントランスポーターとリン恒常性維持機構 Pi ph mm Pi - - E-mail: tatsumi@tokushima-u.ac.jp

More information

Key words: platelet membrane glycoprotein I, platelet adhesion, ristocetin induced platelet agglutination, Bernard- Soulier syndrome, von Willebrand f

Key words: platelet membrane glycoprotein I, platelet adhesion, ristocetin induced platelet agglutination, Bernard- Soulier syndrome, von Willebrand f Key words: platelet membrane glycoprotein I, platelet adhesion, ristocetin induced platelet agglutination, Bernard- Soulier syndrome, von Willebrand factor Blood & Vessel 1984 15: Reduced 図1 常GPIbの 319

More information

YK250 Human GIP (Active) ELISA FOR RESEARCH LABORATORY USE ONLY FAX: TEL: Website: E-mai

YK250 Human GIP (Active) ELISA FOR RESEARCH LABORATORY USE ONLY FAX: TEL: Website:   E-mai YK250 Human GIP (Active) ELISA FOR RESEARCH LABORATORY USE ONLY 418-0011 2480-1 FAX: 0544-22-2770 TEL: 0544-22-2771 Website: www.yanaihara.co.jp E-mail: ask@yanaihara.co.jp . 2. 3. 4. 56. 7. 812. 12. 1213

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 1) Araki, T.: Curr. Opin. Plant Biol., 4, 63-68 (2001) 2) Boss, P. K., Bastow, R. M., Mylne, J. S., Dean, C.: Plant Cell, 16, S18-S31(2004) 3) Simpson, G. G., Dean, C. : Science, 296, 285-289 (2002) 4)

More information

Makoto Onoda, Department of Anatomy and Cell Biology, Georgetown University School of Medicine, 3900 Reservoir Road, N. W., Washington, D. C. 20007, USA Regulation Mechanism of Spermatogenesis : Cell-to-cell

More information

たんぱく3000web.indd

たんぱく3000web.indd 1 2 4 5 3000 6 8 3000 10 10 11 11 12 12 13 13 14 18 19 20 21 Atg 22 23 24 21 X 143000 3000 19 3000 20 25 X 26 27 28 1 20 DNA mrna DNA RNA mrna 3000 DNAmRNARNA SPring-8X Artsimovitch, I. et al., Cell 117,

More information

TECN

TECN WKO BIO WINDOW lyo in situ wako No.13 UG. 1998 TECN TECN l l l l l l l hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh lyo lyo l J.Clin. Biochem. Nutr., Mebio hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service アデノウイルスベクターの改良と応用 7 ン トネ ガ テ ィ ブ を用 い てRel NF-κBの シグナル の不 活 化 を 試 み た そ の 結 果 IκBの ド ミナ ン トネ ガ テ ィ ブ を ニ ワ ト リ胚 肢 芽 に 接 種 した 群 で は 発 現 率 は低 い もの の 四 肢 の 形 成 阻 害 が 認 め られ この 結 果 は頂 堤 AER)を 除 去 した も の の表

More information

untitled

untitled E-mail: khatano@fms.saitama-u.ac.jp Tel & Fax: 048-858-3535 Toxin Virus Bacterium Glycolipid Glycoprotein Vero toxin (Stx1 and Stx2) Side view Bottom view H H H H N H Grobotriaosyl Ceramide (Gb 3 : Galα1-4Galβ1-4Glcβ-Cer)

More information

Database Center for Life Science Online Service ) [Medical Research Institute, Tokyo Medical and Dental University, Kanda-surugadai, Chiyoda-ku,

Database Center for Life Science Online Service ) [Medical Research Institute, Tokyo Medical and Dental University, Kanda-surugadai, Chiyoda-ku, 2-3-10) [Medical Research Institute, Tokyo Medical and Dental University, Kanda-surugadai, Chiyoda-ku, Tokyo 101, Japan] Regulation of Phosphatidylcholine (Phosphatidylethanolamine) Biosynthesis in Animal

More information

Vol.40 No.5△/△0 目次[三]10.23

Vol.40 No.5△/△0 目次[三]10.23 ! Department of Management, Miyagi University, 2 2 1 Hatatate Taihaku-ku Sendai, Miyagi 982 0215 Industrial Technology Institute, Miyagi Prefectural Government, 2 2 Akedoori Izumi-ku Sendai, Miyagi 981

More information

本文/YA7261E

本文/YA7261E J. Cell Biol.,,. Segev, N.Curr. Opin. Cell Biol.,,. Lafont, F., Lecat, S., Verkade, P., & Simons, K.J. Cell Biol.,,. Mostov, K.E., Verges, M., & Altschuler, Y.Curr. Opin. Cell Biol.,,. Sato, T., Mushiake,

More information

Database Center for Life Science Online Service

Database Center for Life Science Online Service 1) Bittner, J. J.: Science, 84, 162 (1936) 13) Michalides, R., van Ooyen, A., Nusse, R.: Curr. Top. Microbiol. Immunol., 106, 57-74 (1983) 2 z Yamamoto, K. R.: Ann. Rev. Genn., 19, 209-252 (1985) 3) Evans,

More information

D., Nicola, N. A., Hilton, D. J.: Nature, 387, 917-921 (1997) 12) Alexander, W. S. : Nat. Rev. Immunol., 2,410-416 (2002) 13) Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P., Shuai, K. : Science,

More information

1...z04/08/.e2

1...z04/08/.e2 August 2004 29 α α 30 Functional Glycomics News Letter No.4 α α August, 2004 31 β ü β α β α 32 Functional Glycomics News Letter No.4 α β August, 2004 33 34 Functional Glycomics News Letter No.4 α β ü August,

More information

1) Ellis, R. W., PeFeo, D., Shih, T. Y., Gonda, M. A., Young, H. A., Tsuchida, N., Lowry, D. R., Scolnick, E. M.: Nature, 292, 506-511 (1981) 2) Barbacid, M.: Annu. Rev. Biochem., 56, 779-827 (1987) 3)

More information

Microsoft Word _abstract_kasai_ikeya2_tk.docx

Microsoft Word _abstract_kasai_ikeya2_tk.docx 科学研究費補助金新学術領域研究 スパースモデリングの深化と高次元データ駆動科学の創成 最終成果報告会 (207/2/8-20) NMR (NMR) NMR! SpM NMR NMR NMR (MaxEnt) (CS) NMR (SpM) NMR NMR ( ) 2 NMR NMR 2 NMR NMR NMR n n- 2 NMR E-mail: kigawa@riken.jp 2 (non-uniform

More information

et al

et al et al et al Comparative Biochemistry and Physiology. Part B FOOD Style 21 et al et al et al et al J. Cetacean Res. Manage Science Rep. int. Whal. Commn Sci. Rep. Whales Res. Inst Balaenoptera bonaerensis

More information