1 2006 msv 2 2011 3 CT 2011 10mSv 10 40mSv 4 2012 217mSv 5 (CT) 2012 50 60mSv 6 2012 510mSv BRCA25 310 10mSv3% BRCA60-280% 3 5m Sv 1m Sv 12%
. http://www.rea.or.jp/ire/pdf/report4.pdf
1.10 20 SMR 1.00 0.90 0.80 0.70 1990-94 1995-99 2000-04 2005-09
1.10 15 SMR 1.00 0.90 0.80 0.70 1990-94 1995-99 2000-04 2005-09
1.10 10 SMR 1.00 0.90 0.80 0.70 1990-94 1995-99 2000-04 2005-09
SMR 1.10 1.00 0.90 5 0.80 0.70 1990-94 1995-99 2000-04 2005-09
1.10 SMR 1.00 0.90 0.80 0.70 1990-94 1995-99 2000-04 2005-09
10mSv BRCA Pijpe A, Andrieu N et al. Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE- RAD- RISK). BMJ. 2012 Sep 6;345:e5660 http://www.bmj.com/content/345/bmj.e5660.pdf%2bhtml
Anouk Pijpe BMJ 2012 BRCA30217 1.63.8 3 BRCA
BRCA X0.5mSv 25
X X 5 Andrieu N et al. Effect of chest X- rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO- HEBON, and IBCCS Collaborators' Group. J Clin Oncol. 2006 Jul 20;24(21):3361-6. Epub 2006 Jun 26.
CT 195% PearceLancet 2012
CT 195% PearceLancet 2012
X 1. CT 828615 2. 12020 3. 10mSv3 4. 10mSv3% 40mSv12% CMAJ. 2011 Mar 8;183(4):430-6. Epub 2011 Feb 7. Cancer risk related to low- dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction. Eisenberg et al.
1.200 1.100 1.000 1.000 X (+3%) 1.028 +3%/10mSv (+6%) 1.058 1 (+9%) 1.088 (+12%) 1.119 0.900 0.800 0mSv 10mSv 20mSv 30mSv 40mSv msv 0mSv=1.000;2SD Eisenberg CMAJ. 2011
5m Sv 1m Sv 12 This work was supported by the Department of Health for England and Wales, Scottish Government and CHILDREN with CANCER (UK), Kendall GM. et al. A record- based case- control study of natural background radiation and the incidence of childhood leukemia and other cancers in Great Britain during 1980-2006.. Leukemia. 2012 Jun 5. doi: 10.1038/leu.2012.151.
Kendall GMLeukemia,2012 95% 95% mgy
10mSv3 10mSv 3 351 1001 100mSv101
103 10030 1004.7
1.001.35% 100 () 30% 3%
1. 2.
2013311 office@acsir.org 25
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1995 Thyroid 105 57 5 29
Ito M, Yamashita S, Ashizawa K, Namba H, Hoshi M, Shibata Y, Sekine I, Nagataki S Thyroid5536581995 5FNA 55,04526,406 28,648 1,396197FNA17151120 26171 441712.32 6.418.731.024 30
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010 57 14145 1 12,285 0 8,949 2 12,147 0 10,578 1 11,095 1 55,054 4 33
1838 3 7 20130213 34
http://mainichi.jp/select/news/20130214k0000m040061000c.html : 20130213 2040 35
5 1 5 36
57 1 5 5 55,054 38,114 4 3 7 * 16mm 1015mm Ito M, Yamashita S, Nagataki S Thyroid5 53658 1995 20132 37
* http://onlinelibrary.wiley.com/doi/10.1002/(sici)1097-0215(19960103)65:1%3c29::aid- IJC6%3E3.0.CO;2-3/pdf Int J Cancer. 1996 Jan 3;65(1):29-33. Histopathological characteristics of childhood thyroid cancer in Gomel, Belarus. Ito M, Yamashita S, Ashizawa K, Hara T, Namba H, Hoshi M, Shibata Y, Sekine I, Kotova L, Panasyuk G, Demidchick EP, Nagataki S. http://www.minpo.jp/news/detail/201302146637 38
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57 2 55,054 38,114 40
2 57 2 8,949 38,114 41
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10 1 12 57 http://www.rri.kyoto- u.ac.jp/nsrg/seminar/no91/malko_comments.pdf 2003 3 9 Malko 43
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367 55,054 Our results provide the first epidemiological evidences of cytologically diagnosed childhood thyroid diseases among 55,054 children and suggest a high incidence of thyroid cancer and possibly also of autoimmune thyroid disease around Chernobyl. In radiosensitive children, the thyroid may be affected directly or indirectly, by either immediate exposure to radiation or continuous exposure to low- dose radiation in the contaminated area. To shed light on these possibilities, long- term follow- up studies should be organized through international scientific cooperation. This study will serve as an important data base for further analyses, and suggests that childhood thyroid diseases, including both neoplasms and immunological disorders, are consequences of radioactive fallout. 45
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matsuzak@maple.ocn.ne.jp