2014 6 1 6 Review Article Proposal for Outcome Verification of Iyakubungyo and Future Directions Miwako Kamei 1, Mitsuko Onda 2, Kazuko Akagi 3, Tomohide Akase 4, Noriko Fukushima 5, Noriko Miyamoto 6 1 School of Pharmacy, Nihon University 2 Osaka University of Pharmaceutical Sciences 3 Hitotsubashi University 4 Japan University of Economics, Guraduate School of Business 5 Faculty of Social Pharmacy, Keio University 6 Tokyo University of Pharmacy and Life Sciences Received: March 11, 2014 Accepted: March 12, 2014 Abstract: The system where patients receive only prescriptions from physicians and go to community pharmacies to receive their medications is called iyakubungyo in Japan. Although the system has been almost established nationwide over the last several decades, criticisms have been occasionally heard since around the year 2000. This article evaluates the kinds of advantages that the development of iyakubungyo gives the population, at the same time summarizing the background to the criticisms against the system and discussing the ideal way of separation to resolve the issues. Key words: Iyakubungyo, community pharmacy, dispensing, medication 1
2014 6 7 12 原 著 S 1, 2 1 1 1 1 2 1 2 2012 6 1 2013 8 26 S S S 148 4 72 49 6 / 60 7 / 12 20 7 / S S OTC 7
2014 6 13 21 原 著 1 2 1 1 1 3 1 1 1 1 1 2 3 2013 8 7 2013 9 10 254 13
2014 6 22 27 原 著 1 1 1 2 2 2 1 1 1 1 2 2013 8 31 2013 9 13 0.6 0.1 0.2 0.1 0.2 0.6 22 Pharmacy Society of Japan
2014 6 28 36 原 著 2013 9 9 2013 10 17 2004 976 138 12.9 15 7 3 9 6 2 p<0.01 28 Pharmacy Society of Japan
2014 6 37 42 原 著 1, 2 3 3 4 1 1 1, 5 6 7 2 1 2 3 4 5 6 7 2013 8 18 2013 11 11 AMD AMD AMD 2 5 AMD DEA AMD / BMI p<0.01 p<0.05 3 DEA / BMI p<0.01 AMD BMI 3 TDM 37
2014 6 43 48 1 1 1 2 1 2 2013 5 31 2013 9 19 PTP HPLC 56 76 3 43
2014 6 49 56 1 1 1 2 2 2 1 1 2 2013 7 22 2013 10 18 1617 5 6 328 2 87.3 93.7 52.9 40.4 63.4 87.8 49
2014 6 57 61 1 1, 2 2 2 2 2 2 1, 2 1 2 2013 8 14 2013 11 7 200 40.5 42.0 13.6 14.8 57
2014 6 62 66 Note Quality Evaluation of Famotidine and Cimetidine for Proper Use of Over-the-counter Medications Aayako Kato, Chika Nakayama, Taeyuki Oshima Kinjo Gakuin University School of Pharmacy Received: June 6, 2013 Accepted: November 26, 2013 Abstract: In 2008, the Pharmaceutical Affairs Law was revised. Under the new law, over-thecounter drugs (OTC) were classified into three categories, Schedule I, II and III, in descending order based on risk of adverse reactions. A new OTC marketing system was introduced, allowing only pharmacists to sell Schedule I drugs. However, there is relatively little information on OTC when compared with ethical drugs. In this study, we compared the quality of two Schedule I drugs (famotidine and cimetidine) with ethical drugs by means of dissolution tests. Although the results confirmed that these drugs meet the appropriate standards, some OTC showed lower dissolution rates while others showed higher rates. These differences are thought to influence absorption, as well as the action and side effects of the drug. Our findings show that more specific information about quality should be provided with each OTC. Key words: over-the-counter drug, Schedule I, famotidine, cimetidine, dissolution test 62 Pharmacy Society of Japan
2014 6 67 75 1 1 2 1 1 2 1 1 2 2013 8 8 2013 12 6 45 89 /198 64 26 QOL 67
2014 6 76 83 1 2 2 1 1 2 2013 9 13 2013 12 24 20 9 76 Pharmacy Society of Japan
2014 6 84 92 TS-1 1 2 1 3 1 1 2 NPO Health Vigilance 3 2013 9 18 2014 1 22 TS-1 TS-1 TS-1 290 190 123 42 51 TS-1 TS-1 84 Pharmacy Society of Japan
2014 6 93 96 1 1 1 2 1 1 2 2013 10 19 2014 1 27 A B C K 1 Kurnik 1 25 μg K 1 1 A 141 ± 40.0 L B 11.3 ± 5.58 L C 2.91 ± 0.370 L n=3 mean±sd K 1 K 1 93
2014 6 97 105 I 1 2 2 1 1 1 2 2013 12 16 2014 2 14 要 旨 : -VG 10 5 3 2 ph キーワード: -VG 97