Fig.1 Histograms of the sum of glucose concentrations for venous whole blood(vg)during 75 g OGTT in normal control subjects(a)and outpatients(b) Table1 Whole blood capillary-and venous-glucose levels in normal control subjects(group A)and outpatientst(group B) t:subjects who were suspected to be glucose intolerant and in whom GTT was examined in our out patient clinic.they were subdivided into three groups(normal,igt and diabetes). *1:Capillary whole blood was obtained from the ear lobes. *2:Venous whole blood was obtained from the antecubital vein. *3:Difference in glucose concentration between capillary and venous blood samples(capillary minus vein). *:p<0.01 or less vs normal control subjects
Fig.2 Correlation between venous glucose concentrations(vg)and C-V difference(cg-vg)during 75 g OGTT. :normal control subjects(group œ A); :outpatients(group B); r:correlation coefficient
Fig.3 IVG and C-V difference(mean }SE)in subjects subdivided by levels of VG ƒ -:normal control subjects(group A);:suspected glucose intolerant outpatients(group B) Table 2 Number of cases according to results of 75 g OGTT
Fig.4 Relationship between diagnostic criterial concentrations of CG and number of unmatched cases assessed by VG or CG values :total number of unmatched cases:...:number - of cases of IGT by CG who were normal by VG:-:number of cases who were normal by CG and IGT by VG
1) WHO Expert Committee on Diabetes Mellitus (1980) Technical Report Series No.646, W110, Geneva 3) Whichelow M, Wigglesworth A, Cox I3I),Abrams ME (1967) Critical analysis of blood sugar measurements in diabetes detection and diagnosis. Diabetes. 16: 215 226 6) Neese JW, Duncan P, ftlyse I), Robinson Ni, Cooper s, Stewart C (1976) Development and evaluation of a hexokinase/glucose 6 phosphate dehydrogenase procedure for use as a national glucose reference method, I IEW publication No. (CDC) 77 8330, U. S. Department of health, Education and Welfare, Public Health Service, Center for Disease Control, Atlanta, Georgia, U. S. A. 13) National Diabetes Data Group (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28: 1039 1057
Abstract Difference between Capillary and Venous Blood-Glucose Concentrations during 75 g OGTT,Including Diagnostic Criteria for Normal Values Presented by the Committe of the Japan Diabetes Society Mayumi Furuta",Iliromi Toshiko Yoneda",Toshimasa Nakayama', Koji Nakanishi*2 and Tetsuro Kobayashi' *'Department of Clinical Chemistry,Toranomon Hospital,Tokyo *2 Department of Endocrinology and Metabolism,Toranomon Hospital,Tokyo We studied differences in glucose levels between capillary(c)and venous(v)whole blood from 75 normal control subjects(group A)and 141 outpatients suspected to have glucose intolerance (group B)on the basis of 75 g OGTT. Maximum values of the mean C V difference were found at 60 min in group A and 120 min in IGT and in diabetic subjects of group B.A significant inverse relationship was also observed between V glucose concentrations and C V differences after glucose ingestion.these findings suggest that the time required to reach the maximum CV difference is prolonged in the setting of glucose intolerance,and that C V differences under these conditions are smaller than those under healthy conditions. Of 216 subjects,31 ultimately had different diagnoses depending on the measurement of either C or V glucose,i.e, 25 out of the 31 subjects were diagnosed as IGT when evaluated by C glucose,and found to be normal when assessed by V glucose. These findings demonstrate that the criterion recommended by the committee of the Japan Diabetes Society,for judging C blood glucose levels,may be low as compared to that for V glucose. J.Japan Diab.36(8):631-637,1993