A HE Bar m CD Barm U/l U/l. cm mm
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- ひろじ よしなが
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1 短 報 A 要 約 T A A. A A,,, A, A 症例 kg, / l,, / l FAX daisuke@animal-wellness.co.jp
2 A HE Bar m CD Barm U/l U/l. cm mm
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4 A CD CD HLA DR.... A A,, euthyroid sick T T A,, T T, T, 引用文献 Gross TL Ihrke PJ Walder EJ Affolter VK Mauldin EA, Scott DW, Miller WH Jr, Smith CA : Malassezia dermatitis in the dog: a retrospective histopathological and immunopathological study of cases ( ), Vet Dermatol,, () Rojko JL, Hoover EA, Martin SL : Histologic interpretation of cutaneous biopsies from dogs with dermatologic disorders, Vet Pathol,, () Scott DW, Miller WH : Primary seborrhoea in English springer spaniels: a retrospective study of cases, J Small Anim Pract,, ()
5 Ihrke PJ, Goldschmidt MH : Vitamin A-responsive dermatosis in the dog, J Am Vet Med Assoc,, () Medleau L Hnilica KA Watson TDG : Diet and skin disease in dogs and cats, J Nutr,, S S () Mineshige T, Kamiie J, Sugahara G, Yasuno K, Aihara N, Kawarai S, Yamagishi K, Shirota M, Shirota K : Expression of periostin in normal, atopic, and nonatopic chronically inflamed canine skin, Vet Pathol,, () Yager JA Wilcock BP New LLL Gross TL Ihrke PJ Walder EJ Affolter VK Gross TL Ihrke PJ Walder EJ Affolter VK Jackson HA, Olivry T, Berget F, Dunston SM, Bonnefont C, Chabanne L : Immunopathology of vesicular cutaneous lupus erythematosus in the rough collie and Shetland sheepdog: a canine homologue of subacute cutaneous lupus erythematosus in humans, Vet Dermatol,, () High Efficacy of Vitamin A in an Elderly American Cocker Spaniel Dog with Seborrhea Daisuke KOJIMA, Kyoko KOJIMA, Kazumi OTA and Yoshihiko KOJIMA Kojima Animal Hospital Animal Wellness Center, Akiha, Akiha-ku, Niigata City, , Japan SUMMARY An -year-old, spayed female, buff-colored American cocker spaniel was presented with seborrhea of severe multifocal greasy crusts on the dorsal skin. Histologically, moderate to severe orthokeratotic hyperkeratosis and mild to moderate superficial dermatitis were observed. Malassezia-like organisms were found to be scattered in the keratin of the epidermis and follicular root sheath by using special stains including Periodic acid-schiff stain (PAS) and Grocott s Methenamine Silver stain. Although the moderately inflamed skin lesions were composed of mixed mononuclear cells, T lymphocytes were found to be randomly distributed on the basal layer and the external root sheaths in mildly inflamed skin lesions by using immunohistochemistry and Toluidine blue stain. The dog gradually responded clinically to oral treatment with Vitamin A during the first two months, and was completely cured after five months of treatment. Key words : American cocker spaniel, seborrhea, Vitamin A. Correspondence to : Daisuke KOJIMA (Kojima Animal Hospital Animal Wellness Center) Akiha, Akiha-ku, Niigata City, , Japan TEL FAX daisuke@animal-wellness.co.jp J. Jpn. Vet. Med. Assoc.,, ()
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