- PDF 無料ダウンロード

Size: px

Start display at page:

Download ""

みいかかくはり
5 years ago
Views:

4 Sulfonylurea Receptors Pancreatic Type: SUR1 Cardiac Type: SUR2A Smooth Muscle Type: SUR2B Kir Channels uka-rp-1/kir6.1 BIR/Kir6.2

6 1) Ho K, et al : Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature 1993 ; 362 : ) Kubo H, et al : Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 1993 ; 362 : ) Isomoto S, et al : Inwardly rectifying potassium channels : their molecular heterogeneity and function. jpn Physiol 1997 ; 47 : ) Takahashi N, et al : Molecular cloning and functional expression of cdna encoding second class of inward rectifier potassium channels in the mouse brain. J Biol Chem 1994 ; 37 : ) Morishige K, et al : Molecular cloning, functional expression and localization of a novel inward rectifier potassium channel in the brain. FEBS Lett 1994 ; 341 : ) Lesage F, et al : Cloning provides evidence for a family of inward rectifier and G-protein coupled K channels in the brain. FEBS Lett 1994 ; 353 : ) Isomoto S, et al : A novel ubiquitously-dis tributed isoform of GIRK2 (GIRK2 B) enhances GIRK 1-expression of the G-protein-gated K+ current in Xenopus oocytes. Biochem Biophys Res Coinmun 1996 ; 218 : ) Ashford MLJ, et al : Cloning and functional expression of a rat heart KATP channel (Retraction). Nature 1994 ; 370 : ) Krapivinski G, et al : The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+ channel proteins. Nature 1995 ; 374 : ) Kurachi Y : G protein regulation of cardiac muscarinic potassium channel. Am J Physiol 1995 ; 269 : C 821-C ) Reuveny E, et al : Activation of the cloned muscarinic potassium channel by G prptein fly subunits. Nature 1994 ; 370 : ) Huang CL, et al : Evidence that direct binding of GPy to the GIRK1 G protein-gated inwardly rectifing K+ channel is important for channel activation. Neuron 1995 ; 15 : ) Slesinger PA, et al : Identification of structural elements involved is G protein gating of the GIRK1 potassium channel. Neuron 1995 ; 15 : ) Duprat F, et al : Heterologous multimeric assembly is essential for K+ channle activity of neural and cardiac G-protein-activated inward rectifiers. Biochem Bioj5hys Res Com ; 212 : ) Patil N, et al : A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nature Genetic's 1995 ; 11 : ) Terzic A, et al : Cardiac ATP-sensitive K" channels : regulation by intraellular nucleotides and K+ channle - opening drugs. Am J Physiol 1995 ; 269 : C 525-C ) Inagaki N, et al : Reconstitution of '(ATI, An inward rectifier subunit plus the sulfonylurea receptor. Science 1995 ; 270 : ) Aguilar-Bryan L, et al : Cloning of the /3 cell high-affinity sulfonylurea receptor. A regulation of insulin secretion. Science 1995 ; 268 : ) Thomas PM, et al : Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science 1995 ; 268 : ) Inagaki N, et al : A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.

7 Neuron 1996 ; 16 : ) Isomoto, S et al : A novel sulfonylurea receptor forms with BIR (Kir 6.2) a smooth muscle type ATP - sensitive K channel. J Biol Chem 1996 ; 271 : ) Yamada M, et al : Sulfonylurea receptor 2 B and Ki,-6.1 form a sulfonylurea-sensitive but ATP-insensitive K channel. J Physiol 1997 ; : ) Takumi T, et al : A novel ATP-dependent inward rectifier potassium channel expressed predominantly in glial cells. J Biol Chem 1995 ; 270 : ) Hibino I-I, et al : An ATP-dependent inwardly rectifying potassium channel, (Kir4.1), in cochlear stria vascularis of inner ear : its specific subcellular localization and correlation with the formation of enclocochlear potential. J Ncurosci 1997 ; 17(12) : ) Ishii M, et al : Expression and clustered distribution of an inwardly rectifying potassium channel. KA,-2/Kir 4.1, on mammalian retinal Milller cell membrane : their regulation by insulin and laminin signals. Neurosci 1997 ; 17 (20): ) Lesage F, et al : TWIK-1 a ubiquitous human weakly inward rectifying K+ chanel with a novel structure. EMBO ; 15 : ) Dong-Hee Kim, et al : A cloning and functional expression of a novel cardiac two-pore background K+ channel (ctbak-1) Cure Res (in press)

2

2 3 4 5 6 7 8 9 1 2 3 4 5 10 11 12 1 2 1 2 1 2 13 14 3 17 15 1 2 3 D Usefulness of Tc-99m MIBI SPECT in predicting multidrug resistance gene expression level in non-small cell lung cancer a preliminary