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1 * * MRI T 2 * 1 9 CT MRI T 2 * T 2 *WI 1 MRI T1bN0M0 stage I / cm 46.7 kg 204/116 mmhg 113/ SpO l/ 36.7 C manual muscle testing MMT 1 2 National Institute of Health Stroke Scale NIHSS g/dl 2.3 g/dl AST 64 U/l ALT 52 U/l LDH 438 U/l ALP 804 U/l γ-gtp 106 U/l CRP 2.75 mg/dl 516 mg/dl D-dimer 7.5 μg/ml FDP 15 μg/ml 30 CT 1 Fig. 1 2 MRI diffusion weighted image DWI T 2 *WI DWI Fig. 2 MRA CT *Corresponding author:
2 臨床神経学 53 巻 2 号 Fig. 1 Brain computed tomography (CT) after 30 minutes from onset. The brain CT showed multiple air-isodense spots in the right hemisphere and a spot under the skin in the left temporal region. Fig. 2 Brain magnetic resonance (MR) images after 2 hours from onset. (Signa Excite 1.5T, GE Healthcare) Diffusion weighted images (DWI) (Axial, 1.5T; TR 10,000 ms, TE 89.5 ms) showed slightly hyperintense lesions in the right cerebral hemisphere (A), and T2* weighted images (Axial, 1.5T; TR 420 ms, TE 30 ms) showed many hypointense spots in the right cerebral hemisphere (B). Fluid attenuated inversion recovery (FLAIR) MR images (Axial, 1.5T; TR 8,000 ms, TE 130 ms) showed no abnormality (C).
3 脳空気塞栓症の 1 例 Fig. 3 Serial T2* weighted images. Many hypointense spots were shown in the right cerebral hemisphere after 2 hours from onset (Axial, Signa Excite 1.5T, GE Healthcare; TR 420 ms, TE 30 ms) (A). After 7 hours from onset, the hypointense spots spread (Axial, Signa Excite HD 3.0T, GE Healthcare; TR 420 ms, TE 30 ms) (B). These spots disappeared after 53 days (Axial, Signa Excite HD 3.0T, GE Healthcare; TR 420 ms, TE 30 ms) (C). たがう所見をみとめなかった 経過 臨床経過と画像所見より脳空気塞栓症と考え エダ 考 察 ラボンを開始した 診断した直後に胸腔洗浄をおこなった主 科と当科より患者の家族に対して病状説明をおこなった 患 われわれは胸腔洗浄中 咳嗽直後に右への眼球共同偏倚や 者の家族はこの説明に対し十分に納得していた 発症約 3 時 左片麻痺などの神経症候の発現と 頭部 CT での多数の空気 間後に痙攣発作が出現し その後重積状態となったため 気 濃度の陰影から本例を脳空気塞栓症と診断した 発症 2 時間 管内挿管および痙攣のコントロールを目的にバルビツレート 後と 7 時間後の脳 MRI-T2*WI でみられた多発低信号は第 54 とフェニトインを投与した 発症約 7 時間後の頭部 MRI で 病日にはほぼ消失していた 最終的な梗塞巣は主に右側脳室 は T2*WI でみとめた空気はさらに小さくなり拡散していた 周囲の白質にみとめられ 右前頭葉や右頭頂葉 右側頭葉内 Fig. 3 また発症 26 時間後の頭部 CT では空気陰影は消失 側の皮質下と白質はわずかにみとめられるだけであり 発症 しており 右大脳半球の広範囲に浮腫と梗塞巣と考えられる 低信号域がみとめられた 第 3 病日にバルビツレートを中止 時予想された梗塞巣よりも小さい範囲にとどまった 脳空気塞栓症の原因としては 外傷1 やカテーテル操作2 すると再度痙攣重積が出現したため バルビツレートを再開 体外循環を使用した手術 CT ガイド下肺生検3 心肺蘇生 し フェノバールとバルプロ酸ナトリウムを追加し 痙攣の 術4 などの医療行為による合併症が多数報告されている そ コントールをおこなった 痙攣発作の頻度は低下し 徐々に れらの発症機序は 処置にともない肺静脈に空気が流入し 意識障害と左片麻痺は改善した 第 54 病日の頭部 MRI では その空気が体循環に入ったためと報告されている5 本例の 梗塞巣は主に右側脳室周囲の白質にみとめられ 前頭葉や頭 ように膿胸洗浄中に発症した脳空気塞栓症は学会での症例報 頂葉 側頭葉内側の皮質下と白質にはわずかにみとめられる 告が 2 例あるのみで文献的報告はない 本例で空気が肺静脈 のみであった T2*WI では空気を示唆する多数の低信号は一 に入った機序は 胸腔内に抗がん剤を注入中に脳空気塞栓症 部残存しているものの 大部分が消失していた Fig. 3 転 を発症した Yamashita6 らの報告のように 慢性膿胸に随伴 院時 第 127 病日 には MMT で 4 から 4 の軽度左片麻痺 する肺炎のため肺静脈と末梢気管支に小さな瘻孔ができてお と左半側空間無視は残存するものの 歩行器使用下で短距離 り 胸腔洗浄中に咳嗽が出現して胸腔内圧が上昇し その内 歩行は可能であり modified Rankin scale mrs は 3 であった 圧が肺静脈圧よりも上昇し 肺静脈に空気が流入したためと
4 CT Yamashita CT CT MRI-T 2 *WI MRI-T 2 *WI T 2 *WI T 2 *WI MRI T 2 *WI 10 7 T 2 *WI 2 8 MRI-T 2 *WI microbleeds mrs 3 MRI T 2 *WI CT MRI COI 1 Akaishi K, Hongo K, Obinata C, et al. Pneumoangiogram in a patient with severe head injury. Case illustration. J Neurosurg 2000;93: Yang CW, Yang BP. Massive cerebral arterial air embolism following arterial catheterization. Neuroradiology 2005;47: Um SJ, Lee SK, Yang DK, et al. Four cases of cerebral air embolism complicating a percutaneous transthoracic needle biopsy. Korean J Radiol 2009;10: Hashimoto Y, Yamaki T, Sakakibara T, et al. Cerebral air embolism caused by cardiopulmonary resuscitation after cardiopulmonary arrest on arrival. J Trauma 2000;48: CT ;66: Yamashita Y, Mukaida H, Hirabayashi N, et al. Cerebral air embolism after intrathoracic anti-cancer drug administration. Ann Thorac Surg 2006;82: Takizawa S, Tokuoka K, Ohnuki Y, et al. Chronological changes in cerebral air embolism that ocurred during contineuous drainage of infected lung bullae. Cerebrovasc Dis 2000;10: Griese H, Seifert D, Koerfer R. Cortical infarction following cardiosurgical procedures air embolism as a probable cause. Eur Neurol 2009;61: CT ;21: Yip CY, Yoon D, Olafsson V, et al. Spectral-spatial pulse design for through-plane phase precompensatory slice selection in T2*- weighted functional MRI. Magn Reson Med 2009;61:
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Abstract The main theme of this paper is the effect on trade caused by the process of establishing the Chubu Region Scheme as the third broad economic area in Japan followed by the Tokyo Metropolitan Area
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Medical Journal of Aizawa Hospital Medical Journal of Aizawa Hospital Vol. 8 (2010) Key words Neuropsychopharmacology Neuroscientist Curr Opin Neurol Clin Rehabil J Neurol Neurosurg Psychiatry
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第32回 日本頭頸部癌学会ランチョンセミナー6 Pre-Meeting Abstract FDG-PET の頭頸部癌における臨床的有用性 司会 長 放射線治療センター長 講演 1 耳鼻咽喉科 部長 講演 2 PETセンター長 岡村 光英 先生 日時 2008年6月13日 金 12:00 13:00 会場 ハイアットリージェンシー東京 共催 第32回 日本頭頸部癌学会 日本メジフィジックス株式会社 136-0075
1. Paul, L. W. and Juhl, H.: The Essentials of Roentgen Interpretation. Harper & Row, Publishers. pp. 339-355, 1972. 2. Norman, D., Diamond, C. and Boyd, D.: Relative detectability of intracranial calcifications
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Postoperative Assessment by Using a Torque Machine (BIODEX) and MRIs in Patients treated for a Recurrent Anterior Dislocation or Subluxation of the Sh
Postoperative Assessment by Using a Torque Machine (BIODEX) and MRIs in Patients treated for a Recurrent Anterior Dislocation or Subluxation of the Shoulder by HATA Yukihiko MURAKAMI Narumichi Department
