299 資料前田壽登 2 山木範泰東 2 眞 Code No 緒言 single photon emission computed tomography SPECT positron emission computed tomogra

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1 299 資料前田壽登 2 山木範泰東 2 眞 Code No 緒言 single photon emission computed tomogrphy SPECT positron emission computed tomogrphy PET SPECT PET SPECT SPECT 3 γ 1 5 6, 7 SPECT SPECT worksttion; WS SPECT 8, 9 Development of the Softwre Pckge of the Nucler Medicine Dt Processor for Eduction nd Reserch Histo Med, 1 Noriysu Ymki, 2 nd Mkoto Azum 2 1 Fujit Helth University 2 Imging Informtion Technology Center, Nihon Medi-Physics Co., Ltd. Received April 11, 2011; Revision ccepted Decemer 6, 2011 Code No. 390 Summry The ojective of this study ws to develop personl computer-sed nucler medicine dt processor for eduction nd reserch in the field of nucler medicine. We cll this softwre pckge Prominence Processor (PP). Windows of Microsoft Corportion ws used s the operting system of this PP, which hve imge resolution nd vrious 63 pplictions clssified into 6 groups. The ccurcy ws exmined for lot of pplictions of the PP. For exmple, in the FBP reconstruction ppliction, there ws visully no difference in the imge qulity s result of compring two SPECT imges otined from the PP nd GMS- 5500A (Toshi). Moreover, Normlized MSE etween oth imges showed Therefore the high processing ccurcy of the FBP reconstruction ppliction ws proven s well s other pplictions. The PP cn e used in n ritrry plce if the softwre pckge is instlled in note PC. Therefore the PP is used to lecture nd to prctice on n eductionl site nd used for the purpose of the reserch of the rdiologicl technologist on clinicl site etc. widely now. Key words: nucler medicine dt processor, prominence processor *Proceeding uthor Vol. 68 No. 3 Mr 2012

300 Fig. 1 An initil screen imge of the Prominence Processor with 6 min processing uttons (left side) nd menu rs (upper side). SPECT WS personl computer PC 1.

2 300 Fig. 1 An initil screen imge of the Prominence Processor with 6 min processing uttons (left side) nd menu rs (upper side). SPECT WS personl computer PC 1. 方法 1-1 grphic user interfce GUI 1 2 SPECT Operting system OS PC OS Windows 2 PC GUI C Fig. 1 GUI File Util.Imge Disp. File Util. File Utility Imge Disp Fig filtered ck projection FBP SPECT FBP SPECT I-123 IMP SPECT

3 301 Fig. 2 Min processing uttons with 6 groups including vrious ppliction softwre FBP SPECT SPECT Tools triple energy window TEW 3 Chng 2 SPECT PC Fig mm Fig mm FBP SPECT 2. 結果 2-1 FBP SPECT Fig. 4 SPECT Fig. 4 Fig. 4 Fig. 4c WS GMS-5500A 65 PC Intel Core2 Qud Q GHz 4 GB 1.86 Vol. 68 No. 3 Mr 2012

4 302 Fig. 3 Exmples of the numericl phntom. () The exmple of the numericl phntom using circles. () Brin phntom mde possile simulting vrious cererl lood flow t severl segments. Fig. 4 Reconstructed I-123 rin SPECT imges. () trnsxil imge () coronl imge (c) sgittl imge c PC Intel Core2 Duo T GHz 2 GB Fig Fig. 5 FBP SPECT cycles/cm 64 Fig. 6 SPECT Fig. 6 SPECT

5 303 Fig. 5 Screen imges of Genertion of projection dt for the numericl phntom () nd reconstruction of the numericl phntom (). Fig. 6 Reconstructed SPECT imges of numericl phntoms with () nd without () sctter nd ttenution correction Fig Fig. 7 Fig. 7c SPECT Fig. 7d SPECT 2-3 WS WS GMS- 5500A FBP Fig. 8 GMS-5500A SPECT SPECT normlized men squre error Normlized MSE 考察 WS Vol. 68 No. 3 Mr 2012

Lower imges show the reconstructed SPECT imges with (d) nd without sctter nd ttenution correction (c). Fig.

6 304 c d Fig. 7 Exmple of numericl rin phntom with cererl lood flow of 1:3 (white mtter:gry mtter). () nd () shows originl rin phntom nd projection dt of this phntom respectively. Lower imges show the reconstructed SPECT imges with (d) nd without sctter nd ttenution correction (c). Fig. 8 Comprison of SPECT imges reconstructed y the prominence processor nd the WS (TOSHIBA GMS-5500A). It is visully difficult to recognize the difference etween oth imges FBP ordered susets expecttion mximiztion OS-EM WS GMS-5500A

7 305 WS Fig. 3 SPECT FBP OS-EM WS CD PC SPECT 4. 結語 6 63 SPECT WS WS WS GMS- 5500A PC 謝辞 Vol. 68 No. 3 Mr 2012

8 306 参考文献 1 Sorenson JA. Quntittive mesurement of rdioctivity in vivo y whole-ody counting. ACADEMIC PRESS, New York nd London, 1974; Chng LT. A method for ttenution correction in rdionuclide computed tomogrphy. IEEE Trns Nucl Sci 1978; 25(1): Ichihr T, Ogw K, Motomur N, et l. Compton sctter compenstion using the triple-energy window method for single-nd dul-isotope SPECT. J Nucl Med 1993; 34(12): Jszczk RJ, Greer KL, Floyd CE Jr, et l. Improved SPECT quntifiction using compenstion for scttered photons. J Nucl Med 1984; 25(8): Meikle SR, Hutton BF, Biley DL. A trnsmission-dependent method for sctter correction in SPECT. J Nucl Med 1994; 35(2): Yokoi T, Shinohr H, Onishi H. Performnce evlution of OSEM reconstruction lgorithm incorporting three-dimensionl distnce-dependent resolution compenstion for rin SPECT: simultion study. Ann Nucl Med 2002; 16(1): Med H, Ymki N, Ntsume T, et l. Simultneous sptil resolution correction in SPECT reconstruction using OS-EM lgorithm. Igku Butsuri 2004; 24(2): SPECT 1995; 45(Suppl): Q&A2006: : : version : 311. 図表の説明 Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 Fig. 7 Fig. 8 I-123 SPECT c 1 3 c SPECT d TOSHIBA GMS-5500A

Fig mm X X CT 8 Waters Waters 45 9 X Received Sept. 7, 2007; Revision accepted May 26, 2008; Code No. 241 Summary An axial radiogr

Fig mm X X CT 8 Waters Waters 45 9 X Received Sept. 7, 2007; Revision accepted May 26, 2008; Code No. 241 Summary An axial radiogr 948 60 Fig. 1 23mm 15 17 X XCT 8 Wters Wters 45 9 X Received Sept. 7, 2007; Revision ccepted My 26, 2008; Code No. 241 Summry An xil rdiogrph of the zygomtic rch is tken in cses of ptients with fcil trumtic

299 資料 前田壽登 2 山木範泰 東 2 眞 Code No 緒言 single photon emission computed tomography SPECT positron emission computed tomogra

299 資料前田壽登 2 山木範泰東 2 眞 Code No 緒言 single photon emission computed tomography SPECT positron emission computed tomogra