Lisa MacGregor Suzie Calne Kathy Day Jane Jones Alison Pugh Jane Walker Printwells, Kent, UK RWS Group, London, UK 2007 Keith Harding Medical Educatio

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1 THIRD CONGRESS OF THE LAUNCHED AT THE WUWHS TORONTO, CANADA 4-8 JUNE 2008

2 Lisa MacGregor Suzie Calne Kathy Day Jane Jones Alison Pugh Jane Walker Printwells, Kent, UK RWS Group, London, UK 2007 Keith Harding Medical Education Partnership (MEP) Ltd Omnibus House, North Road, London N7 9DP, UK Tel: + 44 (0) Fax: +44 (0) info@mepltd.co.uk : MEP Ltd 2008 Smith & Nephew Smith & Nephew 2 Department for Plastic Surgery, Hand and Burn Surgery, University Hospital of RWTH, Aachen 3 Cardiff and Vale NHS Trust Keith Harding Principles of best practice: Wound infection in clinical practice: London: MEP Ltd, Keryln Carville, Silver Chain Nursing Association and Curtin University of Technology, Perth Janet Cuddigan, University of Nebraska Medical Center, Omaha, Nebraska Jacqui Fletcher, University of Hertfordshire, Hatfield Paul Fuchs, University Hospital of RWTH, Aachen Keith Harding, Wound Healing Research Unit, Cardiff University David Keast, University of Western Ontario, London, Ontario David Leaper, Wound Healing Research Unit, Cardiff University Christina Lindholm, Kristianstad University Prashini Moodley, University of KwaZulu Natal, Durban Elia Ricci, St Luca s Clinic, Pecetto Torinese Greg Schultz, University of Florida, Gainesville, Florida Jose Vazquez, Wayne State University, Detroit, Michigan

3 1. Healy B, Freedman A. ABC of wound healing. Infections. BMJ 2006; 332: n n n n n n 1 (critical colonisation 1 1 * *? 2 1

4 2 n n BOX 1 BOX 1 n n n n * * n * n n n 3 bridging bridging ASEPSIS 5 CDC 6 4 2

5 4 2-4 n n 5 7 n 10 BOX 5 n n n n 10 BOX 5 n 10 BOX 5 n 2. Cutting KF, Harding KG. Criteria for identifying wound infection. J Wound Care 1994; 3(4): Gardner SE, Frantz RA, Doebbeling BN. The validity of the clinical signs and symptoms used to identify localized chronic wound infection. Wound Repair Regen 2001; 9(3): European Wound Management Association. Position Document: Identifying criteria for wound infection. London: MEP Ltd, Wilson AP, Treasure T, Sturridge MF, Grüneberg RN. A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis. Lancet 1986; 1(8476): Horan TC, Gaynes RP, Martone WJ, et al. CDC definitions of nosocomial surgical site infections 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 1992; 13(10): Remick DG. Pathophysiology of sepsis. Am J Path 2007; 170(5): Lever A, Mackenzie I. Sepsis: definition, epidemiology and diagnosis. BMJ 2007; 335: Levy MM, Fink MP, Marshall JC, et al SCCM ESICMACCPATSSIS International sepsis definitions conference. Crit Care Med 2003; 31(4): n n 10 BOX 5 n 7 9 i i i n * n 10 BOX 5 * n n n n n n 10 BOX 5 n 2 n bridging 3 n * n n n 10 BOX 5 n n 4 n n * 2 3

Position Document: Identifying criteria for wound infection. London: MEP Ltd, 2005. 5. Wilson AP, Treasure T, Sturridge MF, Grüneberg RN.

6 BOX 2 1cm 2? BOX 2 n * n * 3 4 n n * 4

7 5 n n 5 n n n n n n n 10 n n n n n 10. World Union of Wound Healing Societies (WUWHS). Principles of best practice: Wound exudate and the role of dressings. A consensus document. London: MEP Ltd, n n n n n ESRC CRP 5

8 BOX 5? 7 8 n n 2 6

9 11. Drosou A, Falabella A, Kirsner R. Antiseptics on wounds: an area of controversy. Wounds 2003; 15(5): n n n n BOX 3 n n ] n n n n n 11 7

controversy. Wounds 2003; 15(5): 149-66.

10 12. Leaper DJ. Silver dressings: their role in wound management. Int Wound J 2006; 3: Cooper RA. Iodine revisited. Int Wound J 2007; 4: Molan PC. Honey as a topical antibacterial agent for treatment of infected wounds. Available at: com2001november Molanhoney-as-topicalagent.html. Accessed January Parnés A, Lagan KM. Larval therapy in wound management: a review. Int J Clin Pract 2007; 61(3): BOX n n? 5 5 8

Honey as a topical antibacterial agent for treatment of infected wounds. Available at: www.worldwidewounds.

11 16. Lipsky BA, Berendt AR, Deery HG, et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004; 39(7): Hernandez R. The use of systemic antibiotics in the treatment of chronic wounds. Dermatol Ther 2006; 19: References cited on page 10: 18. Bergstrom N, Allman RM, Carlson CE, et al. Clinical Practice Guideline Number 15: Treatment of Pressure Ulcers. Rockville, Md: US Department of Health and Human Services. Agency for Health Care Policy and Research AHCPR Publication No Arnold TE, Stanley JC, Fellows EP, et al. Prospective, multicenter study of managing lower extremity venous ulcers. Ann Vasc Surg 1994; 8(4): MRSAVRSA Acinetobacter Clostridium difficile BOX 4 BOX 4 n n n n 12 n n n n n 16 n n

Clinical Practice Guideline Number 15: Treatment of Pressure Ulcers. Rockville, Md: US Department of Health and Human Services. Agency for Health Care Policy and Research. 1994.

12 BOX 5 n 5 mm 2 n n 2 30% 19 1 n n n n n PVP-I n n PVP-I n n n n (PHMB) n n n Ag + n n n n 10

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書（案）

特殊病態下感染症における抗菌薬治験の手引き作成委員会報告書（案） VOL.51 NO.6 JUNE 2003 JUNE 2003 9) Niederman MS et al: Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy and prevention.