好酸球性副鼻腔炎:診断ガイドライン（JESREC Study）
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1 : : JESREC Study Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis Study : JESREC Study CT NSAIDs CT : JESREC Study
2 JESREC Study ph CTMRI Caldwell Luc Caldwell Luc Kennedy Stammberer Functional endoscopic sinus surgery endoscopic sinus surgery : ESS Caldwell Luc ESS ESS
3 JESREC Study CT CT 1 CT /ml ESS CT CT
4 JESREC Study : Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis Study JESREC Study ESS IgE CT 2 Kaplan Meier ESS Kaplan Meier Cox NSAIDs Cox Cox Cox Kaplan Meier
5 JESREC Study Cox p NSAIDs 3 Cox p 4 JESREC Study 3 Kaplan Meier : : : p 0 01 ESS step wise Receiver operating characteristic AUC
6 JESREC Study Kaplan Meier p 0 01
7 JESREC Study 2015 Churg Strauss CT NSAIDs : : : : p 0 01 : : : : p 0 01 ESS JESREC Study 5 ESS endotype Th2 IL 5 IgE allergic fungal sinusitis IL 32 JESREC Study IL 5 IL 13 IgE L plastin IL 17 IL 22 IL 31 IL 33 Yamanaka N, Iino Y, Uno Y, et al : Practical guideline for management of acute rhinosinusitis in Japan. Auris Nasus Larynx 2015 ; 42 : 1 7. Fokkens WJ, Lund VJ, Mullol J, et al : European Position Paper on Rhinosinusitis and Nasal Polyps Rhinol Suppl 2012 ; 23 : 3 p preceding table of contents, Akdis CA, Bachert C, Cingi C, et al : Endotypes and phenotypes of chronic rhinosinusitis : a PRACTALL document of the European Academy of Allergy and Clinical
8 JESREC Study Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 2013 ; 131 : ,,, : JESREC Study. ; :. Caldwell GW : Diseases of the accessory sinuses of the nose, and an improved method of treatment for suppuration of the maxillary antrum. New York Med J 1893 ; 58 : Luc H : Une nouvelle methode operatoire pour la cure radicale et rapide de I empyeme chronique du sinus maxillaire. Arch inernat de laryngol otol rhinol et broncho oesophagoscopie, Kennedy DW, Zinreich SJ, Rosenbaum AE, et al : Functional endoscopic sinus surgery : Theory and diagnostic evaluation. Arch Otolaryngol 1985 ; 111 : Stammberger H : Endoscopic endonasal surgery ; concepts in treatment of recurring rhinosinusitis. Part I. Anatomic and pathophysiologic considerations. Otolaryngol Head Neck Surg 1986 ; 94 : :. JOHNS 2004 ; 20 : ,,, :. ; :. Hashiba M, Baba S : Efficacy of long term administration of clarithromycin in the treatment of intractable chronic sinusitis. Acta Otolaryngol Suppl 1996 ; 525 : ,,, :. ; :. Ishitoya J, Sakuma Y, Tsukuda M : Eosinophilic chronic rhinosinusitis in Japan. Allergol Int 2010 ; 59 : Makino S, Miyamoto T, Nakajima S, et al : Survey of recognition and utilization of guidelines for the diagnosis and management of bronchial asthma in Japan. Allergy 2000 ; 55 : :. ;.,,, : : JESREC Study. ; :. Tokunaga T, Sakashita M, Haruna T, et al : Novel Scoring system and algorithm for classifying chronic rhinosinusitis ; The JESREC Study. Allergy 2015 May 6 Epub ahead of print. Matsuwaki Y, Ookushi T, Asaka D, et al : Chronic rhinosinusitis : risk factors for the recurrence of chronic rhinosinusitis based on 5 year follow up after endoscopic sinus surgery. Int Arch Allergy Immunol 2008 ; 146 : Haruna S, Shimada C, Ozawa M, et al : A study of poor responders for long term, low dose macrolide administration for chronic sinusitis. Rhinology 2009 ; 47 : Nakayama T, Yoshikawa M, Asaka D, et al : Mucosal eosinophilia and recurrence of nasal polyps new classification of chronic rhinosinusitis. Rhinology 2011 ; 49 : :. JOHNS 2011 ; 27 :
JJIAO 34 4 : , 2016 総 説 1 1 chronic rhinosinusitis with nasal polyp: CRSwNP chronic rhinosinusitis without nasal polyp: CRSsNP CRSwNP C
JJIAO 34 4 : 203 209, 2016 総 説 1 1 chronic rhinosinusitis with nasal polyp: CRSwNP chronic rhinosinusitis without nasal polyp: CRSsNP 2016 14 CRSwNP CRSsNP osteomeatal complex: OMC 2001 1) 15 2016 9 25
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耳展 長 32:6 舩 宏 隆,他 表2 症状 の改 善率 と臨床 病型 表3 レ線 的改 善率 と臨床 病 型 M.N. 14歳 臨 床 症型:浮 腫茸 状 型 手 術 法:両 前篩 骨 洞 開放 術 両 下鼻 道 開 窓術 治療 効 果:両 側著 明改 善 2年 術 前 術 後 症 例1 40 (550) 上 顎 洞 開 窓 術(小 児) 耳展 32:6 M.H. 13歳 臨床 病 型1浮 腫
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