日本呼吸器学会雑誌第44巻第5号
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2 Table1 Referencesfor(Aex)ofIP researcher term foraex n() age %dead journal Kondoh 3(3) 61.0 Chest1993;103:1808 Akira accelerateddeterioration 17(14) Am JRoentgenol1997;168:79 Stern advancediprequiringmechanical ventilationforacute 23(19) Chest2001;120:213 Saydain IPadmitedtoICU 38(25) AJRCC 2002;166:839 ATS/ERS ConsensusClassification AJRCC 2002;165:277 Ambrosini 5(4) EurRespirJ2003;22:821 Rice terminaldad inip 12(10) 66.0 Am JClinPathol2003;119:709 Al-Hameed 25(23) CanRespirJ2004;11:117 Okamoto 28(20) Thisreport
3 Table2 SummaryofclinicaldataatthediagnosisinpatientswithIP total withoutaex Aexwithin2yrs Aexafter2yrs Aexatdiagnosis number(male) 112(87) 84(67) 13(7) 5(5) 10(8) age 67.9± ± ± ± ±10.2 PaO2 77.4± ± ± ± ±13.0 %VC 77.4± ± ± ± ±27.7 DLco/VA 3.14± ± ± ± ±1.49 BAL-PN 7.5± ± ± ±13.7 BAL-Ly 8.1± ± ± ±4.2 WBC 7,449±2,607 7,214±2,090 6,395±1,475 7,360±2,091 10,820±4,869 CRP 1.54± ± ± ± ±6.80 LDH 243± ±54 306±86 230±73 432±252 IgG 2,007.7± ,005.8± ,168.5± ,735.0± ,976.9±661.1 KL-6 1,504±1,467 1,325±1,434 1,601±923 2,537±1,822 SP-D 383.6± ± ±95.5 1,297.3±1,493.1 ig.1 AnalysisofthecauseofdeathinpatientswithIP.(A,B)56of112patientswithIPdiedduring theobservationperioddueto(aex),lungcancer(lc),chronic (CR),andlowers.(C)Thediferenceofthecausesofdeathbetweenthe earlydeath group and the late-death group,who died within and after1 yearfrom the diagnosis, respectively.themajorcauseofdeathwasaexintheearly-deathgroup,andlcinthelate-deathgroup.
4 Table3 SummaryofcaseswithAexofIP causeof death complications initial symptons trigger foraex treatment survival time (mo) month from diagnosis onsetofaex date sex age candidiasis increasedhypoxia, Jan Apr DIC generalfatigue therapyfor lungcancer Apr candidiasis taperingof corticosteroid 0.4 eb Oct taperingof corticosteroid pulse Jan candidiasis 0.4 eb postbal 1.3 Oct lungcancer CPA Dec cardiac DIC,atrialfluter therapyfor lungcancer Dec lungcancer 20.1 Jan Jan aspergilosis Jan O renal hemosputum Apr alive 16.2 Jun alive CV pyosputum 70.1 Jan CV, pneumothorax pyosputum CPA Jan pneumomediastinum CPA 4.6 Apr CV,DIC, pneumothorax ay O DIC Oct DIC Dec DIC hemosputum 0.6 ay O aspergilosis postbal sivelestat 4.7 Jun DIC, pneumothorax sivelestat 0.9 Jun candidiasis,cv 0.9 eb P.carini,CV Apr P.carini,CV, atrialfluter, sivelestat Jun-03 70, sivelestat 0.4 Jan Abbreviations:CPA;cyclophosphamide,;cyclosporineA,CV;cytomegalovirus,O;multipleorgan,DIC;disseminatedintravascularcoagulation
5 ig.2 Kaplan-eiersurvivalcurvesinpatientswithIP.The5-yrsurvivalrateandmediansurvivial time(st)was38.3% and3.1yr(37.0months),respectivelyintotalippatients.theippatientswith lungcancer(lc)orwith(aex)hadpooroutcomes.ontheotherhand,patientswith neitheraexnorlchadbeterprognosis,inwhichthe5-yearsurvivalrateandst was57.2% and7.3yr (87.1months),respectively. ig.3 AnalysisoflungcancerinpatientswithIP.(A)Coincidenceoflungcancer(LC)wasseen23of112 (20.5%)patientswithIP,and12of23(52.1%)patientswithLCandIPdiedduetoLCduringtheobservationperiod.(B)TheclinicalstageofLCatthediagnosis.Notethatalmost3/4caseswereinitialydiagnosedinanadvancedstage(stage II,IV).
6 ig.4 (A)Therelationbetweentheonsetof(Aex)andthetimeafterthediagnosisof IP.Thirteenof18casesofAex(72.2%)occurredwithin2yearsafterthediagnosisofIP.Tencases withaexatthetimeofdiagnosisofipwereexcludedfrom theanalysis.(b)therewasnosignificant correlationbetweenthetimeofaexand%vcatdiagnosis. ig.5 (A)Triggersof(Aex)weresuggestedtobes(32.1%),bronchoalveolarlavage(7.1%),taperingofcorticosteroid(7.1%),andtherapyoflungcancer(7.1%),andnot specifiedintherestofpatients(46.4%).(b)thest aftertheonsetofaexwas0.9month.thetreatment ofthepatientswithaexwithmethylprednisolone(mpsl)-pulsetherapyincombinationwithcyclophosphamide(cpa)orcyclosporinea ()didnotsignificantlyimprovetheprognosisofaexcompared withsimplempsl-pulsetherapy.
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Table 1 Profiles of 28 patients with Legionella pneumonia in Japan, 1980-1990 a) Y Taguchi, personal communication b) M. Hayase, personal communicatio
Key words: Legionella pneumonia, culture-positive, Japanese patients Legionella (L. pneumophila (L. micdadei, L. bozemanii, Table 1 Profiles of 28 patients with Legionella pneumonia in Japan, 1980-1990
A study of urinary immunoglobulins excretion after forced lordosis MASAKO MIHATA Department of Pediatrics, Hyogo College of Medicine, Hyogo, Japan (Di
A study of urinary immunoglobulins excretion after forced lordosis MASAKO MIHATA Department of Pediatrics, Hyogo College of Medicine, Hyogo, Japan (Director : Prof. Hiroyoshi Wada) Key word : orthostatic
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The Track & Field -- -- 1 10:00 11:30 14:00 15:00 15:00 16:30 jog 10:00 11:00 14:00 10:00 9:00 10:30 11:00 12:00 15:00 17:00 14:00 15:00 20:00 21:00 15:00 16:30 10:00 10:30 km 10:30 11:30 14:00 15:30 16:00
CHEMOT HERAPY
CHEMOT HERAPY CHEMOT HERAPY NOV. 1973 Table 1 Co-laboratory clinics CHEMOT HIRAPY 1537 CHEMOT HERAPY NOV. 1973 CHEMOT HERAPY 1539 Table 3 Distribution by age groups No significant difference in age and