簡易な嗅覚評価のための「日常のにおいアンケート」

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Olfactory Evaluation Using a SelfAdministered Odor Questionnaire Kenzo Tsuzuki, Keijiro Fukazawa, Hironori Takebayashi, Hideki Oka, Takaki Miwa, Yuichi Kurono, Kenichi Nibu, Shoji Matsune, Jun Uchida, Masayoshi Kobayashi,YasushiOhta, Hideaki Shiga, Tatsu Kobayakawa, Masafumi Sakagami Department of Otolaryngology, Hyogo College of Medicine Fukazawa Ear, Nose and Throat Clinic Department of OtorhinolaryngologyHead and Neck Surgery, Graduate School of Medical Science, Kanazawa University Department of Otolaryngology, Faculty of Medicine, Kagoshima University Department of Otolaryngology, Kobe University Graduate School of Medicine Department of Otorhinolaryngology, Showa University School of Medicine Department of OtorhinolaryngologyHead and Neck Surgery, Mie University Graduate School of Medicine Department of Otorhinolaryngology, Saitama Medical Center, Jichi Medical University National Institute of Advanced Industrial Science and Technology, Institute for Human Science and Biomedical Engineering TEL FAX Emailkenzo@hyomed.ac.jp

We evaluated a 20item selfadministered odor questionnaire for assessing olfactory function, proposed in 2003 by the Japan Rhinologic Society committee on olfaction tests. The 20items selected based on results of olfactory studies in Japan were steamed rice, miso, seaweed, soy sauce, baked bread, butter, curry, garlic, orange, strawberry, green tea, coffee, chocolate, household gas, garbage, timber, stercusshit, sweat,flower,andperfume. Subjects were 302 people 179 men and 123 womenaverage age : 35.7 years having no history of nasal or paranasal disease and tested between December 2004 and December 2007. Subjects were asked to score items as follows : always smelled 2 points; sometimes smelled 1 point; never smelled 0 points; or unknown or no recent experience no score. Scores were calculated and represented using a percentage. Response was 993300/302, with two subjects excluded for reporting more than 10 unexplainable items. The mean score was 95.2n300. Of the 302, 28193.0agreed on the number and 25283.4on the content of items. Scores correlated statistically significantly with those of a visual analogue scale rs0.501, p0.0001, n300. We concluded that the selfadministered odor questionnaire is useful in assessing olfactory function in normal subjects. The next step will be to administer the questionnaire to diseased or otherwise compromised subjects to determine whether it is useful for clinically diagnosing such olfactory dysfunction. Key wordsselfadministered odor questionnaire, olfactory evaluation, questionnaire score olfactory VAS T &TT &T T &T

A B 38% Olfactory VAS 10cm % Visual Analogue ScaleVAS olfactory VAS 10cm VAS VAS Spearman standard deviation ; SD n300 n2

n300 % 100 90 80 70 60 50 40 30 20 (n = 300) 10 0 0 10 20 30 40 50 60 70 n104 n95n61 n32 n6 VAS n300 VAS n2 n104 n95n61 n32 n6 VAS Spearman rs0501p00001n300

25 21 20 15 14 16 16 15 10 5 0 6 8 8 2 4 1 8 2 0 7 2 7 1 0 1 VAS% % olfactory VAS T &T odor stick identification test ; OSIT olfactory VAS T & T T &T olfactory VAS VAS VAS T & T T & T OSITJ

Takagi SF : A standard olfactometer in Japan. A view over ten years. Ann NY Acad Sci 1987 ; 510 : 1138..,,,,, pp 2023.,,,..,,,,.. McCormack HM, Horne DJ, Sheather S : Clinical applications of visual analogue scales : a critical review. Psychol Med 1988 ; 18 : 100719. Hashimoto Y, Fukazawa K, Fujii M, et al : Usefulness of the odor stick identification test for the Japanese patients with olfactory dysfunction. Chem Senses 2004 ; 29 : 56571.,,,.. Kobayashi M, Saito S, Kobayakawa T, et al : Cross cultural comparison of data using the odor stick identification test for Japanese OSITJ. Chem Senses 2006 ; 31 : 33542. Saito S, AyabeKanamura S, Takashima Y, et al : Development of a smell identification test using a novel stick type odor presentation kit. Chem Senses 2006 ; 31 : 37991.