* 1 6 ( ) 20 GOT GPT ( ) 59 3 CT F D T3 *

-259 3101 * 1 6 () 20 GOTGPT 3 155169 2 5 () 59 3 CT 129 59 F D T3 * -- 428 -

-259 3101 * 3 5 4 6 () 159 NOS () 158 159 R 4U T3 500ml 2ml 2g 100ml 25mg PL 162 152 152 37 1630 92mg/dl PL 3g/ 3 300mg/ 3 150mg/ 3 157 WBC 12000/mm 3 CRP 8.8g/mlBS 238mg/dl HOE901 166 450 mg/ 3 157 166 R R T3PL 7%PL -- 429 - *

-259 3101 * 5 2 ( ) 4 4 169 ope 204 ope 210 231 2 294 210 231 294 AGML * -- 430 -

-259 3101 * 6 5 NOS () 68 67 PM11 123mg/dl 68 AM2 AM3 20mg/dl ICU diazepam 180mg/dl 69 AM12 71 CT 73 / 86 6/4 300mg/dl 2 77 79 / 1066/5 83 1288/5 108 R 67 23:00 68 A.M2:00 69 71 CT 77 * -- 431 -

-259 3101 * 7 5 () 161 161 170 8 2 NOS () 145 145 146 0 20% Glucose 60ml 400mg/dl 500ml R 10 DIV FPG 277mg/dl R 10 311mg/dl 20%Glucose 60ml 400mg/dl 500ml R 10 DIV FPG277mg/dl R 10 311mg/dl PL SP 20% R * -- 432 -

-259 3101NPH * 9 3 NPH NOS () 135 135 136 140 141 PL T3CEZ 10 5 NPH NOS () 70 70 PL * -- 433 -

-259 3101NPH * 11 3 NPH NOS () 71 66 71 + hcg 200 73 74 coagula D&C 76 76 free space hcg320 SMBG 338mg/dl GI D&C hcg 40 80 Villi R N O R10% * -- 434 -

-259 3101NPH * 12 3 NPH NOS () 87 87 88 8788 ALP 13 6 NPH ( ) 21 20 PM7:00 R 10 21 AM1:002:00 AM3:004:00 AM7:00 R 38 22 36hr 22 R (7/6/7) N (8) 31 / 20 * -- 435 -

-259 3101NPH * 14 6 NPH () 122 122 8 50 9 30 10 43 15 4 NPH ( ) 49 53 49 SR 16 2 NPH NOS () 69 69 R 5% -- 436 -

-259 3101NPH * 17 2 ( ) 43 42 40 (A1 2 clipping Hb 8.5g/dl 40ml/30mg / 40mg/ 36 H1 38 40mg 27 Hb 10.4g/dl 26 50mg2 23 Hb 10.6g/dl R-R-R-N 4 20 6 H2 Hb 13.8g/dl 1 NPH 40 2 Clipping 36 30 RRRN 4 20 PL 5% 0.9% 50% R SP MS T3G G S * -- 437 -

-259 3102 * 1 6 NOS () 32 2 1 GOT 21 IU/LGPT 26 IU/L HOE901 27 GOT:228 IU/LGPT:211 IU/L 32 34 9.4mg/dLGOT 284 IU/LGPT 507 IU/LGTP 2316 IU/L ALP 710 IU/LLDH288IU/L HOE901 35 ( :504 IU/L)HBs HCV () 37 GOT 349 IU/LGPT 682 IU/L 38 IgMHA () 39 MRI 41 GOT 222 IU/LGPT 555 IU/L 227 IU/L 43 GOTGPT 48 GOTGPT PTP 50 57 GOTGPT 77 98 GOT 22 IU/LGPT 18 IU/L 1.3 mg/dl 137 57 77 34137 * -- 438 -

-259 3102 * 2 5 () 44 44 145 38 146 150 161 161 MRSA 161 161 189 193 181 13 224 283 316 190 HOE901 N 150 () 44 * -- 439 -

-259 3102 * 3 5 ( ) 65 65 77 L4/5 84 L5S1 root block 91 93 (25)1T 7793 84 L5S1 root block () () -- 440 -

-259 3102 * 4 5 5 6 ( ) 14 NOS () 155 14 ( A) 90 Ope 97 (90 ) 9097 155 156 11:00 (+)(+) 35.8 157 HOE901 3U 160 (±)(+)(±(+) 158 ( 38.3 () 35.3 159 35.8 ( 160 (+)(+) 161 HOE901 2U ( 162 ( 163 HOE901 167 C 156 167 163 0 HA (AC-17) C () VG A -- 441 - *

-259 3102NPH * 7 5 NPH () 124 1 EKG 124 142 203 EKG 245 124 142 30R 124 2 8 8 6 NPH NOS () 149 149 164 CT 179 182 K * -- 442 -

-259 3102NPH * 9 7 NPH () 3 90 112 126 145 MRI 2 C ( ) * -- 443 -

-259 3102NPH * 10 5 NPH NOS () 63 61 ( 63 2T 6T ) () 64 65 3T 2T 66 67 chest X-P 67-89 R OD S * -- 444 -

-259 3102NPH * 11 6 NOS () 1 1 S58 follow 1 followup 23 33 Biopsy malignancy+ Biopsy 1 23 30 42 12 6 B (()) 7 () 12 25 28 33 9 28 33 53 () L * -- 445 -

-259 3102NPH * 13 5 NOS ( ) 1 1 92 ope 93 Ope 95 9295 (93 ope ) 1 size 45 19mm 14 6 NPH ( 92 98 100 105 ( ) 100151 -- 446 -

-259 3103 * 1 * 2 1 4 3101 IDDM 5 5 168 3.8mg 2.5ml 1 1 190 3.8mg 2.5ml 1 1 211 3.8mg 2.5ml 1 1 253 HOE901 344 318 264 ope R HOE901/3103 * 1 * 2 -- 447 -

-259 3103 * 1 * 2 2 3 3101 IDDM NOS 311 311 3839 315 13300/mm 3 CRP 14.27mg/dl X S6 Ceftriaxone 1g 1 2 318 CRP 3.98mg/dl 321 CRP 0.82mg/dl Ceftriaxone 322 Amoxicillin 250mg 1 4 326 R S6 Ceftriaxone 2g/ 3 315 315322 * 1 * 2 -- 448 -

-259 3103 * 1 * 2 3 2 3101 IDDM 221 107 128 4 184 205 226 231 245 248 281 245281 SR Cap R 20% P P T R * 1 * 2 -- 449 -

-259 3103-1 * 1 * 2 4 3 3101 IDDM NOS 392 393 397 394395 396 397 18 393 392 393 R 2 1 * 1 * 2 -- 450 -

-259 3103- / / sick day / / / / / / / / 1. HbA1c 0.5IU/kg 2. 1) 2) / / -- 451 -

-259 3103 * 1 * 2 5 4 3101 (IDDM) 7 245 256 267 245 256 267 R CP P D -T3 C D -P R U40 SP * 1 * 2 -- 452 -

-259 3103 * 1 * 2 6 2 3101 (IDDM) 282 282 284 287 1 288 289 292 1 293 299 327 CT 331 R ETPL S B AM T3 : 287289 292299 327331 * 1 * 2 -- 453 -

-259 3103 * 1 * 2 7 7 3102 (NIDDM) NOS 277 277 295 CT 303 OPE 318 392 OPE 397 HOE901 398 papilloma 412 303318 392 398 G * 1 * 2 -- 454 -

1, 43, 860 (1988) 2, 16, 1631 (2000) 3 The DCCT research group, Diabetes Care 10, 1 (1987) 4 UK prospective diabetes study(ukpds) group, The Lancet 352, 837 (1998) 5,, 195 (1996) 6, 192, 809 (2000) 7 Bradley, C, In Bradley C(ed) Harwood Academic Publishers, 89 (1994) 8,, 12 (2001) 9,,, 153 (1997) 10, 42, 385 (1999) 11,, 38 (1996) 12,,, 18-27 (2002-2003) 13,,, 166-177 (1996) 14,,, 33-65 (2000) 15,,, 276-277 (2002) 16, 84(9), 1672 (1996) 17,,, 230-231 (2002) 18 Hannele Yki-Jarvinen, Diabetes Care 24(4), 758 (2001) 19 Jennal L. Jonhnson, Arch Intern Med.156, 259 (1996) 20,,, 178-206 (1996) 21 Lieberman P, JAMA215, 1106 (1971) 22 Schernthaner G, Diabetes Care 16 (Suppl 3), 155 (1993) 23 Palmer JP, Science 222, 1337 (1983) 24 Fineberg S.E.: Diabetologia 25: 465-469, 1983 -- 455 -