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1911201031 1911 4 4 191111 AAPS Research Achievement in Pharmaceutics and Drug Delivery 1912 8 20 1 1 Thieme Journal Award 2008 20 1 11 19 20 3 25 20 3 25 20 5 21 20 201026 5 17
191126 / 20324 Synthetic Studies on Fluoroalkene Dipeptide Isosteres and their Application to Biologically Active Peptides - Elucidation of modes of membrane permeabilization by antimicrobial peptides in bacterial and mammalian cells and control of their cell selectivity Formation of toxic fibrils of Alzheimer's amyloid -proteins mediated by GM1 ganglioside and its inhibition GM1 Characterization of the Interaction between Peroxin Pex3p and Pex19p involved in Peroxisomal Membrane Protein Translocation peroxin Pex3pPex19p Ca2+ HTLV-1 HBZ c-jun Fgf19 Fgf21 f Functional analysis of BIG1 and BIG2 by RNAi in Membrane traffic GTPase ARF 18
BIG1BIG2 Terminal differentiation of connective tissuetype mast cells Molecular Mechanisms of Prostaglandin E2 Actions in the Preoptic Area E2 Design of artificial 6-zinc finger peptides: linker alteration and DNA binding selectivity 6- DNA N-4-hydroxyphenylretinamide CpG DNA BACE-1 AMPA t Development of novel cancer therapy strategies based on small interfering RNA delivery sirna 20723 NMR structural analysis of G protein activation peptides derived from seven transmembrane G protein-coupled receptors GG NMR 19
2024 E2EP3 K562TPA mirna microrna ESECAT1 ES Zebrafish fibin Zebrafish fgf4 zebrafish fgf19-2 Lumiracoxib D apolipoprotein B Effect of hypoxia on gene expression of the candidate target for treatment of renal cell carcinoma / MATE1/SLC47A1 PEPT1 OAT3 HNK-1 AMPAGluR2 ABCA1 20
TOMA GABRIEL NICOLAE Chemoselective Cross-Coupling Reactions Catalyzed by Iron MG23 GlcAT-I Properties and pathophysiological significance of iron tranporter DMT1 expressed in neurons. DMT1 An epidermal keratinocyte clone with an attenuated interferon- signalling derived from atopic model miceinterferon- Pathological implication of TRPC3 upregulation in reactive astrocytes TRPC3 Involvement of spinal GLT-1, a glial glutamate transporter, in the pathogenesis of inflammatory and neuropathic pain GLT- 1 Period1 Study about the mechanism of synthetic retinoid CD437-induced cell death for development of differentiation therapy of hepatocellular carcinoma CD437 Cytokine induction by CpG free-plasmid DNA/liposome complex in macrophages CpGDNA/ F9 5- fluorouracil SWAP COMBINE PET 2 THP-1 GPR40 Prostaglandin E2 triggers mast cell degranulation via EP3 receptor E2 21
GlcAT-P HNK-1 NMDA 1-methyl-4-phenylpyridinium ion Ca2+ - BMP Brorin-like Neucrin Sensitization of serotonergic neurons to 3,4- methylenedioxymethamphetaminemdma in the rat organotypic mesencephalic slice cultures MDMA CXCR4 Prostaglandin E2-EP4 signaling regulates microtubule cytoskeleton in preoptic neuronsep4 Suppression of hepatic ischemia/reperfusion injury by Kupffer cell targeted delivery of NFB decoy using sugar modified carrier NFB Kupffer The evaluation of transfection characteristics of plasmid DNA and sirna by the mechanical massage to the liver DNA sirna Increased antitumor immunity of heat shock protein 70 by conjugating cell-penetrating peptide. heat shock protein 70 Regulation of transgene expression in interferon gene therapy Factors affecting the expression of antigenes following DNA vaccinationdna Pd Ergot Alkaloid - Lysergol,-Isolysergol 22
, - NMR Prostaglandin EP2 Signaling Sensitizes Cumulus Matrices to Sperm Penetration by Suppressing Chemokine Actions EP2 :-99m MT1-MMP G GPR17b Establishment of gene expression profiles of mouse stomach mast cells Optimization of anticancer drug delivery using PEGylated amino acid dendrimer PEG Basic study on the development of controlled release formulation of troglitazone intended for cancer therapy [C-11]Galanthamine hoct/hmate1 double transfectant 2024 ARONG GAOWA DINH THUY DUONG NFKB LPS 23
24 224DC7 MC124333 general strategy 7 97 2 4 D3 6D21M25M15 44M1 Tito NMRIRMSGCHPLCCD DSC 7 119-209 4
2 DC4MC6 441 1119 9 Thomson Scientific 10 Research Front Award Thieme Chemistry Award 4 4 M1 1. 2. 3. 4. 251 421 12 1 1 2 3 4 25
26 46 DC2 1MC8449 53 1 2 3 4G GPCR 5 NMR GPCR http://www.pharm.kyoto-u.ac.jp/yakkai/ 4 9 3 3DC4MC34 4DC118 X 41X ABC2 3 4X X
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29 MC3425 1950 1 http://www.pharm. kyoto-u.ac.jp/bisei/ DC3 2MC104 2123 2 http: //www.pharm.kyoto-u.ac.jp/channel/ 1
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pharm.kyoto-u.ac.jp/biopharm/ 2007 2007 200711 2 141 411 16 18-22 HPhttp://www.pharm.kyotou.ac.jp/system-biology/ 4 2 2DC2 MC34421 165 3 DC2 MC1 1 2 3 4 Congratulation Party SC 33
34 http:// www.pharm.kyoto-u.ac.jp/sc-molsci/ 1MC342 8 1585 7 Fragment MOFMO FMO 300 20CK2 30M50% 4 6 DC7 MC34013 219 15 21031823 19
35 5 34 18 non coding RNAmicroRNA 1 NEDO 11 1DC6MC7 2120 1G 2 http://www.users.kudpc.kyotou.ac.jp/%7ep51907/negishi/index.html
36 22 742117 1 2 3 4DNA 3F 3 http://www.lif.kyotou.ac.jp/labs/kozutsumi/ DC114MC8 1441 31 41 2 AAPS 2008 Research Achievement Awards in PPDM 1921COE 200971112 2411 2729 http://www.kuhp.kyoto-u.ac.jp/
37 ~yakuzai/main.htm PD1DC3 MC10411 23 1 2DNA 3 JR 1PD1DC8 MC6121 1 2 3 4 5 400MHzNMR
19 PD3 DC2MC2 1DC5MC3 153 KEGG 13 548 121KEGG 8113 61 DNA RNA http://kanehisa. kuicr.kyoto-u.ac.jp/projects_j.html GIW Genome Informatics WorkshopISMB Intelligent Systems for Molecular Biology PSBthe Pacific Symposium on Biocomputing 38
39 20064 20074 3F PD42
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2011 Tel 0757534589 E-mail yakuyu@pharm.kyoto-u.ac.jp Tel 0757214541