Key words: Mycoplasmal pneumonia, Eruption, Pleurisy, Thrombocytopenia, Stevens-Johnson' s syndrome
Table 1 Hospitalized patients with M. pneumoniae infection during November 1975-October 1978
Table 2 Complications of M. pneumoniae infection (November 1975-October 1978) Total number of hospitalized patients: Total number of hospitalized patients with M. pneumoniae infection: 72
Table 3 Hematologic and serologic studies on patient with thrombocytopenia Indirect hemoagglutination test Compliment fixation test
3) Denny, F.W., Cyde, W.A. and Glezen, W.P.: Mycoplasma pneumoniae disease: Clinical spectrum, pathophysiology, epidemiology and control. J. of Infections Diseases. 123: 74-92, 1971. 4) Lerer, R. J. and Kalaysky, S.M.: Central nervous system disease associated with,mycoplasma pneumoniae infection. Pediatrics. 52: 658-668, 1973.
I. Lymphocyte stimulation. Clin. exp. Immunol., 17: 29-41, 1974. 6) Hers, J.F. and Masurel, N.: Infection with Mycoplasma pneumoniae in civilians in the Netherlands. Ann. N.Y. Acad Sci., 143: 447-460, 1967. 15) Lusher, J.M. and Iyes, R.: Idiopathic 8) Cherry, J.D., Hurwitz, E.S. and Welliver, thrombocytopenic purpura in children. R.C. Mycoplasma pneumoniae infections Seminars Thromb. Hemostas., 3: 175-199, and exanthems. J. of Pediat., 87: 369-373, 1975. 1977. 16) Reed, S.E.: Interaction between mycoplasma and respi ratory virus studied in tracheal organ cultures: Pathogenic mycoplasma. A Chiba Fundation Symposium. p. 329. Elsevier Excepta Medica, North-Holland, 1972. 17) Foy, H.M., Kenny, G.E. and Koler, J.: Mycoplasma pneumoniae in Stevens Johnson's syndrome. Lancet, Sept. 3 p. 550-551, 1966. 12) Biberfeld, G., Biberfeld, P. and Sterner, G.: Cell-mediated immune response following Mycoplasma pneumoniae infection in man. Mycoplasmal pneumonia with special regard to its complications Masashi YAMAGUCHI, Keiichi ISOYAMA, Yasuyuki FUJITA, Harumi JYONOUCHI, Hiromichi HANAWA, Naoyoshi YANAGISAWA, Koichiro YAMADA and Akira ISHIKAWA Department of Pediatrics, Showa University Fujigaoka Hospital, Yokohama It is well documented that Mycoplasmal pneumonia breaks out periodically. Recently, we have studied on the complications of this disease in 72 cases (37 male and 35 female) who were hospitalized in the past three years. Of the 72 cases, 40 cases (about 57%) had complications in one form or another. Eruption accounted high incidence with 21 cases (29.2%). Of them, rubella-like eruption showed high incidence, followed by pleurisy 13 cases (18.1%) and epistaxis 10 cases (13.9%). In 6 cases, elevating serum titers against M.pneumonia glomerulonephritis) and high values for ASO (of them, one case shifted to were observed concomitantly, while the M.pneumonia titer was detected in two patients with MCLS and one case with asthmatic attack after M.pneumonia infection. Besides, there were otitis media in four cases, two cases of encephalopathy and one case of meningitis, thrombocytopenia and Stevens_ Johnson's syndrome each. As for the age composition for the cases of complications, those aged 4 to 10 years accounted for the highest incidence with 29 cases (72.5% of total cases). Apparently, this is the age breaked to which at most attention must be paid for further examination and treatment.