untitled

13ｦﾐ ﾌ08 ｦﾐ ﾌ6ｾ4 2003 09 6ﾒ26ﾑ80801O6ｾ4 47

13EFPIA ANNUAL MEETINGS ATHENS 2003 096ﾑ806ｦﾐ6ﾑ801O096ﾑ803 ﾞ 096ﾑ806ｦﾐ6ﾑ801O096ﾑ803 ﾞ O06 罍ﾞ03036ﾒ2ｦﾐ ﾒ ﾇ 6ﾑ809ｦﾐ6ﾒ206O09 ﾇ EFPIA ANNUAL MEETINGS.............................................040003.3 096ﾑ806ｦﾐ ﾇ096ﾒ2ｦﾐ ﾒ70 ﾞ03 ﾞ02O0609 6ﾒ20303 6ｾ40803 ﾞ036ﾒ2706ｾ46ﾑ80303 09O08 03 罔ﾐ03 ﾞ03 6ｾ46ﾒ2 ﾞ 09 ﾞ076ｾ4ｦﾐ ﾞ 6ﾒ20303 6ﾑ86ﾒ2 ﾇ6ｾ4070303 6ｾ40803 ﾞ036ﾒ2706ｾ46ﾑ80303 6ﾒ2 ﾇ0ｹ0 EFPIA 6ｾ46ﾒ2 ﾇ03 ﾞ057003 ﾞ (EFPIA ANNUAL MEETINGS)....................040003.4 ﾞ036ﾒ2 ﾞ 縺0303ｦﾐ6ｾ46ﾒ2ｦﾐ ﾒO6ﾒ2 ﾇ6ﾒ2 ﾞ: ﾇ 6ﾑ808060309 ﾞ07 ﾒ ﾇ 02 ﾞ0609 ﾞ ﾒO08ｦﾐO09 ﾇ01 ﾞ03ｦﾐ ﾞ ﾒｦﾐ030408036ﾑ8086ﾑ8ｦﾐ............................040003.6 ﾞ03 ﾞ056ﾑ80306 ﾇ6ｾ4 ﾇ 6ﾒ2 ﾇ6ｾ4 02 ﾞ0609 ﾞ ﾒ6ﾑ8086ﾒ2ｦﾐ ﾒ ﾇ6ｾ4 03O09O056ﾑ86ｾ4ｦﾐ ﾞ6ｾ4..............................................040003.7 6ｾ4080908O08 ｦﾐO 0809O0806 縺0303 08 縺6ﾑ8ｦﾐ ﾞ6ｾ4 2 ｦﾐO0803ｦﾐO08 2003...............................................040003.7 O0907 ｦﾐ6ﾑ80ｹ0 09O08 03 罔ﾐ03 ﾞ03 6ｾ46ﾒ2 ﾞ 09 ﾞ076ｾ4ｦﾐ ﾞ 6ﾒ2O08 6ｾ408036ﾑ8040607O08 ｱ ﾇ 6ﾑ808060309 ﾇ 6ﾒ2 ﾇ6ｾ4 08 縺6ﾑ8ｦﾐ ﾞ6ｾ4: 036ﾑ86ﾑ86ｾ4 6ﾑ8 6ﾑ808056ﾑ806ｦﾐ6ﾑ86ｾ4 罔ﾐ ﾞ 6ﾒ2O086ｾ4 ﾞ6ｾ4056ﾑ8036ﾑ8ｦﾐ6ｾ4 ｱ 01 ﾞｦﾐ066ﾑ86ﾒ2ｦﾐ6ｾ409O0ｹ0 6ﾒ2O08 6ﾑ809ｦﾐ6ﾒ20709O08 0906O030406O08 6ﾒ2O08 6ｾ4026ﾑ86ﾑ8. ﾒ06 ﾞ6ｾ40906 ﾇ......................................040003.9 04ｦﾐ6ﾑ8080608036ｾ4 ﾇ 6ﾒ2 ﾇ6ｾ4 6ﾑ808060309 ﾞ07 ﾒ ﾇ6ｾ4 6ﾑ803036ｾ4 ﾇ6ｾ4 ﾒ ﾞｦﾐ 08 縺6ﾑ8ｦﾐ ﾞ O09ｦﾐ 07 ﾞ 6ﾒ2O08 0809O0806 絨6ｨ8 08 縺6ﾑ807 ﾞ0ｹ0 ﾒ ﾞ05 ﾇ 罍ﾇ6ﾒ2O6ｨ8 ﾒ. 6ｾ46ﾒ26ﾑ802 ﾞ0370..040003.11 ﾇ 6ﾑ803ｦﾐ ﾞｦﾐ ﾞ 6ﾑ808060309 ﾞ07 ﾒ ﾇ ﾞ 絨06 ﾞ 6ｾ46ﾑ8 6ｾ4016ﾑ86ｾ4 ﾇ 096ﾑ8 6ﾒ2ｦﾐ6ｾ4 09 ﾞ06O016ﾑ86ｾ4 08 縺6ﾑ8ｦﾐ ﾞ6ｾ4 ﾒ ﾞｦﾐ 6ﾒ2 ﾇ03 ﾒOｦﾐ030303ｦﾐ ﾒ ﾇ ﾞ6ｾ402 ﾞ ｦﾐ6ｾ4 ﾇ O09ｦﾐ 07 ﾞ 6ﾒ2 ﾇ0ｹ0 6ﾑ809ｦﾐ6ﾒ206O09O08 ﾞ. 04ｦﾐ ﾞ09 ﾞ036ﾒ2O09O6ｨ8 O08.......................040003.13 6ｾ408030408 ﾞ ﾆO036ﾒ2 ﾞ6ｾ4 03026ﾑ8 6ﾑ8ｦﾐ ﾞ 罔ﾐ ﾞ 6ﾒ2O086ｾ4 ﾞ6ｾ4056ﾑ8036ﾑ8ｦﾐ6ｾ4 ﾒ ﾞｦﾐ Oｦﾐ ﾒO03O09ｦﾐ ﾒ ﾇ 6ﾑ80806036ｾ46ﾒ2ｦﾐ ﾞ 罔ﾐ ﾞ 6ﾒ2 ﾇ03 6ﾑ808060309 ﾇ O09ｦﾐ 07 ﾞ 6ﾒ2O08 0906O030406O08 6ﾒ2 ﾇ0ｹ0 EFPIA SIR TOM MCKILLOP.......040003.18 G-10 O09 ﾞ04 ﾞ 0803 ﾇ O08 6ﾑ809ｦﾐ096ﾑ804O08 罔ﾐ ﾞ 6ﾒ2 ﾇ03 ﾒ ﾞｦﾐ03O6ﾒ2O09ｦﾐ ﾞ ﾒ ﾞｦﾐ 6ﾒ2 ﾞ 02 ﾞ0609 ﾞ ﾒ ﾞ O09ｦﾐ 07 ﾞ 6ﾒ2O08 6ﾑ809ｦﾐ6ﾒ206O09O08 E. LIIKANEN.......................................................040003.20 ﾞ03ｦﾐ6ｾ4O6ﾒ2 ﾇ6ﾒ26ﾑ86ｾ4 6ｾ46ﾒ2 ﾇ03 0906O6ｾ408 ﾞ6ｾ4 ﾇ 6ﾒ20303 6ﾑ808060309 ﾞｦﾐ0303 ﾞ6ｾ4056ﾑ8030303 6ｾ46ﾒ2 ﾞ 036ﾑ8 ﾞ 02 ﾞ0609 ﾞ ﾒ ﾞ O09ｦﾐ 07 ﾞ 6ﾒ2O08 ﾞ036ﾒ2ｦﾐ0906O030406O08 6ﾒ2 ﾇ0ｹ0 EFPIA J. FRANCOIS DEHECQ....................................040003.23 02 ﾞ0609 ﾞ ﾒ ﾞ 罔ﾐ ﾞ 6ﾒ2 ﾇ03 ﾞ0305060309O6ﾒ2 ﾇ6ﾒ2 ﾞ ｰMEDICINES FOR MANKIND ｱ..................................040003.24 ﾒ ﾞ 086ﾒ26ﾑ806 ﾞ 02 ﾞ0609 ﾞ ﾒ ﾞ 罔ﾐ ﾞ 6ﾒ2 ﾞ 09 ﾞｦﾐ04ｦﾐ ﾞ........................................................040003.26 6ﾒ2 ﾞ ﾒ ﾞｦﾐ03O6ﾒ2O09 ﾞ 02 ﾞ0609 ﾞ ﾒ ﾞ 0909O06O0803 03 ﾞ 086ﾑ8 6ﾒ2ｦﾐ036ｾ4O0803 6ｾ4 ﾇ09 ﾞ036ﾒ2ｦﾐ ﾒ ﾞ 6ﾒ2 ﾇ03 ｦﾐ ﾞ6ﾒ206O02 ﾞ0609 ﾞ ﾒ6ﾑ8086ﾒ2ｦﾐ ﾒ ﾇ 096ﾑ806ｦﾐ05 ﾞ 03 ﾇ 6ｾ46ﾒ2ｦﾐ6ｾ4 0809O 6ﾑ8036ﾒ2 ﾞ6ｦ1 ﾇ 0103066ﾑ86ｾ4.................................040003.29 09 ﾇ030809 ﾞ ﾞ09O 6ﾒ2O 縺6ﾑ803ｦﾐ ﾒO 04/036ﾒ2 ﾇ 6ﾒ2 ﾇ6ｾ4 EFPIA BRIAN AGER........................................040003.31 0806 ﾞ04ｦﾐ ﾞ 6ｾ4026ﾑ86ﾑ8 ｰNYXTE6ｾ4 ﾞｦﾐ 罍ﾞｦﾐO08 096ﾑ8 ﾞ 絨086ｾ4 ｱ..................................................040003.32 ORGANIZING COMMITTEE...................................................................p.3 ENGLISH ADDENDUM EFPIA ANNUAL MEETINGS ATHENS 2003 - PRESS RELEASES.......................................p.37 6ｾ400 0ｸ702fi 0208 02006ｦ004080ｹ0 040ｸ7070003090704020902 07: 6ｾ4. 09000307 0406000ｸ7036ｦ007020306 6ｾ46ｦ00702 01090ｹ0 09. 09 03020002070209 (ROCHE) 08apple006ｦ0030ｸ70709 6ｨ803090ｹ0 & 0903o0903 0000 02060400o6ｦ0. 08o0906 02ｨB6ｧ80ｹ0 (GlaxoSmithKline) 09 閨03080ｹ0 09. 09 0402o03070209 (Pfizer) 09 閨03080ｹ0 ﾒ. 09 apple 030ｷ30007 (Janssen- Cilag) 09 閨03080ｹ0 ﾆ0ｷ36ｧ8 09 0902030703 6ｾ4020806040006080300046ｧ9 2 6ｾ4f6ﾑ86ﾑ8 02006ｦ004o0ｹ0 47 09 03 03 閨02o0ｸ70000 020907 o030907070ｷ30409 020ｷ307 0ｸ7apple09030004060607 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 0906 0209 06000ｸ702fi030ｸ7070409 00apple0602o06070ｷ3076ｧ9 0ｹ0 020ｷ307 0000030607 00 0ｹ0. 02. 09 0909 03o6ｦ004090ｹ0 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 6ｾ4. 09000307 0406000ｸ7036ｦ007020306 6ﾑ8apple0604020900o0706020607 05000007020ｷ307. 01030ｸ704o04apple0703090ｹ0 03o000602fi0ｹ0 6ｾ46ｦ0006 5o0ｸ703o0ｹ0 ﾆ. 09 0902030703 6ﾑ8apple0602o06070ｷ3076ｧ9 & 040900fi0406000ｹ0 6ｾ404 閨0400060ｹ0 6ﾑ8. 6ｾ4apple 閨0902 6ﾑ806 06026ｧ8 縺03 0000 02006ｧ9 ﾞ. 09o036ｧ90209 縺03 0000 02006ｧ9 縺000706020607 ﾒ 030902fi07020ｷ307 6ﾑ8. 縺03 6 56 5070709 O0602o07o00060207 05 閨00 02 - o090604026ｧ80306o 04. ﾞ030001fi0903o0ｸ7 6ﾒ200040706026ｧ8 08appleo04026ｧ803060109

13EFPIA Annual Meetings ﾌ0309 070ｷ30206026ｧ8 6ﾑ8apple06020308apple6ｧ8/Organizing committee ﾌ0309 070ｷ30206026ｧ8 6ﾑ8apple06020308apple6ｧ8/Organizing Committee co-chair 09 M. C. Pickaert ﾞ07 apple03090306020306 縺000706026ｧ8 04/ 07020306 EFPIA (6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 O00o04appleo07 6ｧ9 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 02 06 6ｾ40ｸ707 閨04000ｷ307) 09. ﾒ03 040703090ｹ0 6ﾑ8apple6ｧ9020600o0ｹ0 0903fi00 03o0ｹ0 6ｾ4026ﾑ86ﾑ8 (6ｾ46ｦ007 000400o0ｹ0 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 6ﾑ8030307 o0ｹ0) Members Members: 09 B. Kressmann LEEM 09 A. Moroni FARMINDUSTRIA 09 J- M Muschart AGIM 09 M. Mees ASTRAZENECA 09 A. Nolan IPHA 09 I. Sanz De Madrid FARMAINDUSTRIA 09 02. 09 0909 03o6ｦ004090ｹ0 6ｾ402EE 09 6ｾ4. 09000307 6ｾ402EE 09 A. Walter EFPIA 09 ﾆ. 09 0902030703 6ｾ402EE ( 罍 03030602fi0ｹ0 6ｾ46ｦ007 000400o0ｹ0) (ｦﾐ02 030602fi0ｹ0 6ｾ46ｦ007 000400o0ｹ0) (080003090602fi0ｹ0 6ｾ46ｦ007 000400o0ｹ0) (ｦﾐ0303 07 0602fi0ｹ0 6ｾ46ｦ007 000400o0ｹ0) (ｦﾐ04apple 070602fi0ｹ0 6ｾ46ｦ007 000400o0ｹ0) 02006ｦ004o0ｹ0 47 6ｾ4f6ﾑ86ﾑ8 3

13EFPIA ANNUAL MEETINGS ATHENS 2003 EFPIA ANNUAL MEETINGS ATHENS 2003 ﾌ0903fi00 03080ｹ0 02090ｹ0 EFRIA Sir Tom McKilloop ﾇ 0002 03 060703 02090ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 04020ｸ7appleo6ｦ00400 0906 020300060ｹ0 00 閨03000ｹ0 04020907 6ﾑ8030307, 02 03060ｹ0 applefi 26 閨0ｷ30ｹ0 28 09 0ｹ1o0ｸ7 0000 020907 000ｸ702 06036ｧ9 02090ｹ0 6ﾑ80303090706026ｧ80ｹ0 0903o00 036ｧ9 0ｹ0 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 apple03 0900 02oappleo066ｧ803090200 0906 apple03060209 08o0307 04020907 040603 00 0ｹ0 09 apple06o 040900 070206026ｧ8 0002 6ｧ8030ｷ30409 02o0ｸ7 000ｸ7030ｷ3apple 0ｸ802o6ｦ0 08 0300 02000ｸ7020602o6ｦ0 020307 o0ｸ7: 09 00026ｧ80406 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ70409 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 O00o04appleo07 6ｧ9 0ｹ0 6ｾ40ｸ707 閨04000ｷ307 02 06 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 (EFPIA), 09 oappleo6ｧ9 0007020704040002 06 0402o 0900070602fi020003o apple03fi0903 0000 020ｷ307 0002 0903060400-0ｷ307 00EFPIA Annual Meetings 200303 appleo0ｸ7 06o0309 0706030902 07 0400 040ｸ707000309 046ｧ9 0000 02o07 6ｾ46ｦ007 000400o 02 0300 02000ｸ70206020607 6ﾑ8apple06040006-036ｧ804000ｷ307 6ﾑ8030307 o0ｹ0 (6ｾ4.02.6ﾑ8.6ﾑ8.). 6ｾ40ｸ700000002006ｧ904 07 020ｸ7036ｧ90ｷ30ｹ0 0903fi00 03o06, 縺00070602o6ｧ9 0406000ｸ7030ｸ70702 閨0ｹ0 02 06 400 070602 02 04020003 閨0409 020ｷ307 000009 036ｦ00200030ｷ307 08 0300 02000ｸ70206-020607 00apple06040006036ｧ804000ｷ307 02 06 040ｸ707 閨04000ｷ307 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0. 6ﾑ8apple06apple03 鑰07 apple 03 6 503 閨030902 07 070602 02o06 03000602o0ｸ70309o6ｧ9 02o0ｸ7 0900o046ｧ9o0ｸ7 02o00 陦, (02fi04o 0400 0003070602fi fi04o 02 06 00apple6ｧ9apple00 o 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0) 02 0900 0ｸ802o6ｧ9, 0002apple03fi040ｷ3appleo06 040ｸ70303fi- 090ｷ307 040300070607 02 03060ｹ0 02 06 040ｸ70702070202000ｹ0 02o0ｸ7 06000307o6ｦ00ｹ0 026ｦ0appleo0ｸ7. 09 0906 applefi 02060ｹ0 040900 07020602fi020003000ｹ0 0002 0903060400060ｹ0 6ｧ802 07 02o 6ｾ40ｸ707-0306o 0000 03 閨00 00 ﾇ 6ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ0: 03 閨000ｹ0 6ﾑ803000ｸ70300036ｧ9000ｹ0 0906 02o0ｸ70ｹ0 ﾞ04030007006ｧ90ｹ0 02o0ｸ7 6ｾ46ｧ8000003 03 (The Europe of Health ｨC New Freedoms for Today ｯs Patients). ﾇ 閨07 030109 02090ｹ0 0002 6ｧ8030ｷ304090ｹ0 閨09060700 applefi 02o07 08appleo0ｸ70309fi 0809006ｧ9 0ｹ0 K 03090909026ｧ8 ﾒ. 6ｾ4020008 076ｧ8. 6ｾ402oapplefi0ｹ0 02o0ｸ7 6ｾ40ｸ70700 036ｧ9o0ｸ7 6ｧ802 07 09 0707030ｸ70409 020ｷ307 040ｸ7070309020607 appleo0ｸ7 0000appleo 6ｧ9ｨBo0ｸ707 020907 apple03fi046 5 0409 020ｷ307 040300070607 0400 07 閨000ｹ0 030003 apple006ｧ9000ｹ0. 6ｾ40ｸ700000002006ｧ904 07 000002 016ｦ0 0703030ｷ307 o 0903fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02. 縺06060309o0ｹ0 6ｾ40ｸ70206 070702090ｹ0 02 06 o 00apple6ｧ9020600o0ｹ0 0903fi00 03o0ｹ0 0403. 000ｷ3076ｧ9 0ｹ0 ﾒ03 040703090ｹ0. ﾌ0903fi00 03080ｹ0 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02.. 6ｾ40ｸ70206 070702090ｹ0 09 0903 0900 02oappleo066ｧ803090200 040ｸ707070702090409 020ｷ307 Heads of Regulatory Agencies, 0903 6ｧ8 020ｷ307 00apple06020008 036ｧ80ｹ0 020ｷ307 0300fi 060ｷ307 03040607 020ｷ307 ﾒ03 020607-0900030607 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 0906 020907 閨090203060409 08 030007020ｷ307 0000 020907 EFPIA. 6ﾒ2090ｹ0 040ｸ707-07026ｧ804000ｷ30ｹ0 apple03o 陦03000ｸ70400 o 0903fi00 03o0ｹ0 02o0ｸ7 6ﾑ8O02 ﾒ 03090909-026ｧ80ｹ0 01 030703 00appleo0ｹ0 6ｾ4 6 56 50702090ｹ0. 4 6ｾ4f6ﾑ86ﾑ8 02006ｦ004o0ｹ0 47

1309 0002070300 02 0906 020907 ﾞ0703030ｷ3applefi020902 - ﾇ 閨03000ｸ707 046ｧ8000003, 09 030003 apple006ｧ9 6ｦ00306o03 6ｧ802 07 02o 03 閨00 02090ｹ0 閨02030004090ｹ0 appleo0ｸ7 06o0309 070603090200 0000 08o03006ｧ8 020907 2509 00apple 閨020006o applefi 020907 6ｧ9 030ｸ70409 02090ｹ0 EFPIA, 04020907 oappleo6ｧ9 apple03o6 5036ｧ8030902 07 02 00apple0602006ｦ00900 02 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0 04020907 030003 apple006ｧ9 25 0403000700060607 02 06 o06 000ｸ702 06036ｧ9000ｹ0 0906 apple0003 0602-030ｷ3 0707apple020ｸ70109 02090ｹ0 閨03000ｸ707 0ｹ0. 6ﾑ8apple6ｧ904090ｹ0 06o0309 0706030902 07 6ｦ0o 0006 060207 workshops 0000 03 閨00 : 09 0002070300 02 0906 apple 06 0607 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ3040903 0906 02 apple 06 06 0203060207 08070300 02 0000 0402oapplefi 07 0106o03o096ｧ8040006 02o 07o00o0300020602fi appleo0ｸ7 03 0604046ｦ0040006 0402o 00 閨0303o07 0906 02060ｹ0 000902036ｧ90400060ｹ0 apple 06 06 020306020607 08 030007020ｷ307 06040200 07 0702 appleo02036ｧ907o0702 06 0402060ｹ0 07070902000ｹ0 0906 fi04o 02o 0ｸ707 02fi07 02 036ｦ0020003 apple 06 06 0203060207 08070300 02. 6ﾑ802 00 閨03o0ｸ70ｹ0 02090ｹ0 08 03-00 02o6 506o000904 076ｧ9 0ｹ0 0003006ｦ007090ｹ0, o Dr Daniel Vasmant, 0903fi00 03o0ｹ0 02090ｹ0 0006 06026ｧ80ｹ0 o0007 0ｹ0 000309 046ｧ9 0ｹ0 02090ｹ0 EFPIA 0906 02 apple 06 06 0203060207 08070300 02, 02fi07060400 fi0206 006ｧ907 06 00apple0602 020206026ｧ8 09 0707090209 09 ﾒo0607fi020902 07 03076 50006 00 閨0203 apple03o02000600 閨07o0ｸ7: - 03 000703 03036ｦ0070006 020907 閨03000ｸ707 02 06 0707apple020ｸ70109 0006 06020607 apple 06-06 020306020607 08 030007020ｷ307 0906 020907 030003 apple006ｧ9 apple 06 06020607 07fi040ｷ307-03 06 0408 036ｧ9040006 040900 070206026ｧ8 02 06 0ｸ7010900 閨0709 040ｸ7006 5o036ｧ8 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 0402o apple 0902fi040006o 096ｧ90907000403 06 0906 020907 0707- apple020ｸ70109 02 036ｦ00200030ｷ307 apple 06 06 020306020607 08 030007020ｷ307 09 00 ﾇ apple 03o046ｧ8 0ｸ709006ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09 02o 201003 0906 02 03 閨00-02 06006ｦ0030ｸ70704090ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0. 6ﾒ2 閨03o0ｹ0 閨090607 07 040ｸ707 07026ｧ80400060ｹ0 6ｦ0o 00010006 0602000ｸ700 閨070ｷ307 o0007 0ｷ307 02090ｹ0 EFPIA o06 oappleo6ｧ9000ｹ0 0404o03o6ｦ00702 06 0000 02 6ｧ90306 ｨB09026ｧ800 02 appleo0ｸ7 08o03o6ｦ007 02 00006 5fi0306 (EVM European Vaccine Manufacturers) 02 06 02 03 閨00 02 6 506o02000407o03o096ｧ9 0ｹ0 (EBE Emerging Biopharmaceutical Enterprises). 6ｾ402 apple03 6ｧ90406 02o0ｸ7 6ｾ40ｸ70700 036ｧ9o0ｸ7 06o0309 070603090200 040ｸ707 閨0702000ｸ7016ｧ8 026ｦ0appleo0ｸ7 04020907 oappleo6ｧ9 040ｸ700000002006ｧ904 07 o Sir Tom McKillop, 0903fi00 03o0ｹ0 02090ｹ0 EFPIA, o ﾞ070206apple03fi00 03o0ｹ0 02090ｹ0 EFPIA 02. Jean-Francois Dehecq, o 02. 縺0006030906o0ｹ0 6ｾ40ｸ70206 070702090ｹ0, 0903fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02 06 o 02. Brian Ager, 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 02090ｹ0 EFPIA. 00 ﾇ 6ﾑ80ｸ70306apple09 apple03 鐶pple0006 000703 03036ｦ0070006 apple0003060404fi020003o 020907 02 0607o02o006ｧ9, apple03o0ｹ0 fi080003o0ｹ0 020ｷ307 04030007060703 6ｧ8030ｷ30400 o sir Tom McKillop. O 0903fi00 03o0ｹ0 02090ｹ0 EFPIA 閨02 0700 07 0402fiapple090409 020ｷ307 03000007020ｷ307 appleo0ｸ7 appleo020003o6ｦ007 apple03o020003 06fi020902 0906 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9. 6ﾒ2fi07060400 020907 0707090209 07 00apple0602000ｸ70403006ｧ9 09 040ｷ304026ｧ8 0604o0303oapple6ｧ9 000002 016ｦ0 appleo03060206026ｧ80ｹ0 0ｸ709006ｧ9 0ｹ0, 02o06070ｷ30706026ｧ80ｹ0 appleo03060206026ｧ80ｹ0 02 06 08 0300 02000ｸ70206026ｧ80ｹ0 appleo03060206026ｧ80ｹ0: 00O06 04030007006ｧ90ｹ0 04020907 6ﾑ80ｸ70306apple09 046ｧ8000003 apple03o04 o02o6ｦ007 040ｸ7070004060ｹ0 0700fi020003 02 06 02 036ｦ0020003 08070300 02, appleo0ｸ7 03 02o0ｸ70ｹ0 6 5o09036ｧ804o0ｸ707 07 ｨB6ｧ804o0ｸ707 apple0003060404fi- 020003o, 07 appleo02026ｧ804o0ｸ707 000009 036ｦ002000309 apple 03 090ｷ3090602fi020902 02 06 07 閨04o0ｸ707 02 036ｦ002000309 appleo06fi020902 ｨB0ｷ36ｧ80ｹ003. 09 閨040ｷ3 02090ｹ0 000702 0206026ｧ80ｹ0 閨03000ｸ707 0ｹ0, appleo0ｸ7 06000107090006 09 02 0300-02000ｸ70206026ｧ8 0806o000904 076ｧ9 apple03o0408 閨03o0702 06 02000307040206000ｹ0 000ｸ702 06036ｧ9000ｹ0 02 06 00apple0603o09 閨0ｹ0 0402o0ｸ70ｹ0 04030007006ｧ90ｹ0 0906 apple00036ｧ903 036 709 0ｸ76 709036ｧ80ｹ0 appleo06fi020902 0ｹ0 02 06 02 036ｧ8 0ｸ709006ｧ9. 00apple0ｷ30ｹ0 07 09070603060400 09 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 02o 1994, 02o 00 閨0303o07 02090ｹ0 08 0300-02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0 04020907 6ﾑ80ｸ70306apple09 0007 03 apple03 鐶pple0006 07 020003006ｧ9 0400 026ｧ907 0ｸ707o applefi 02o 07 000007fi000007o 0007 06 08 閨03o07 020ｷ307 0300o 6ｧ90ｷ307 03040607 0906 apple000306o03060400fi 020ｷ307 apple 070607 0ｸ709006ｧ9 0ｹ0 0002 020ｷ307 oappleo6ｧ90ｷ307 0ｷ30ｹ0 09070ｷ30402fi 02 08070300 02 appleo020003o6ｦ007 00060203fi 00fi07o appleo04o0402fi. 6ﾒ2 040ｸ704026ｧ800 02 0ｸ7090006o07o0006026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0 0007 閨04o0ｸ707 026ｧ9appleo02 07 020003 6ｧ904o0ｸ707 applefi 020907 0001 0403 閨07060409 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 0303000ｸ707090ｹ0. ﾇ 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9 appleo020003006ｧ9 閨07 07 applefi 02o0ｸ70ｹ0 6 5 040602o6ｦ00ｹ0 040ｸ707020003000402 閨0ｹ0 02090ｹ0 o0602o07o006ｧ9 0ｹ0 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0, 02090ｹ0 00apple0604020900o0706026ｧ80ｹ0 02 06 06 020306026ｧ80ｹ0 apple03ofi o0ｸ7, 02 06 09 00apple06020ｸ7046ｧ9 02090ｹ0 006ｧ907 06 02 03o0306040206026ｧ80ｹ0 040900 046ｧ9 0ｹ0 0906 020907 000ｸ70007030006 02 06 020907 0ｸ709006ｧ9 020ｷ307 appleo0306020607 02090ｹ0 6ﾑ80ｸ70306apple090ｹ003. 02006ｦ004o0ｹ0 47 6ｾ4f6ﾑ86ﾑ8 5

13EFPIA ANNUAL MEETINGS ATHENS 2003 ﾞ0702 090ｷ3070604020602fi020902 : ﾞ0702 090ｷ3070604020602fi020902 : ﾇ 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 08 0300 02o6 506o000904 076ｧ9 020607 0ｸ707006ｦ00006 ﾇ 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 08 0300 02o6 506o000904 076ｧ9 020607 0ｸ707006ｦ00006 6ﾒ2 0402o0604006ｧ9 02o0ｸ7 2002, 00apple066 5006 5 060607o0ｸ707 fi0206 09 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9 006ｧ907 06 閨07 0ｹ0 applefi 02o0ｸ70ｹ0 6 5 040602o6ｦ00ｹ0 02o00006ｧ90ｹ0 0ｸ76 709036ｧ80ｹ0 02000407o03o096ｧ9 0ｹ0 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0. 03040006 0ｸ76 70903 閨0ｹ0 00apple06 fi0400060ｹ0 fi04o07 08o0307 020907 apple 0404fi03090409 (0000 582.500 0006 0602000ｸ700 閨07o0ｸ70ｹ0 0ｸ7apple 03036ｧ803o0ｸ70ｹ0), 020907 apple 03 090ｷ3090602fi020902 ( 016ｧ9 0ｹ0 160 06040002 02o00000ｸ7036ｧ90ｷ307 6ﾑ80ｸ70306, 0400 04o07 030602 閨0ｹ0 020600 閨0ｹ0), 020907 0303000ｸ707 & ﾞ0707apple020ｸ70109 (00apple0007 6ｦ00309-02 07 19,8 06040002 02o00006ｦ00306 6ﾑ80ｸ70306) 02 06 02o apple0300fi07 0400 02o0ｸ7 0000appleo030602o6ｦ0 0604oｨB0ｸ7096ｧ9o0ｸ7 (0000 0300020602fi 0604oｨB6ｦ0-0906o 40 06040002 02o00000ｸ7036ｧ90ｷ307 6ﾑ80ｸ70306). 030402fi04o, applefi 02 0402 02060402060207 0402o0604006ｧ9 apple03o026ｦ0apple020006 fi0206 09 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9 006ｧ907 06 000ｸ707030ｷ30209 02 06 09 0702 090ｷ3070604020602fi02090207 02090ｹ0 0803006ｧ9070006 040ｸ7070004060ｹ0 0400 0404 閨0409 0000 020907 ﾞ0000030602 0706026ｧ8 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9, 09 oappleo6ｧ9 閨040006 0ｸ7016ｧ8040006 020907 020ｸ70306 03046ｧ9 02090ｹ0 appleo020003060702 0ｹ0 applefi03o 閨0301090ｹ0 0906 020907 0303000ｸ707 & ﾞ0707apple020ｸ70109 02 0607o02fi000ｷ307 08 030007020ｷ307. ﾇ 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9, appleo0ｸ7 00apple6ｧ9 0400060307 00020607 6ｧ802 07 apple030ｷ302oapplefi03o0ｹ0 0400 apple 0902fi040006o 00apple6ｧ9apple00 o 04020907 閨03000ｸ707 02 0607o02fi000ｷ307 08 030007020ｷ307, 03fi090ｷ3 o0602o07o0006020607 02 06 06 0602 040206020607 apple06 閨04000ｷ307 閨040006 03046ｧ9040006 07 00000606070006 02060ｹ0 00apple0007 6ｦ00400060ｹ0 04020907 0303000ｸ707 & ﾞ0707apple020ｸ70109 07 閨0ｷ307 08 030007020ｷ307. O06 020ｸ70306fi- 020003o06 03fi09o06 0906 0209 040ｸ70700046ｧ8 6ｦ001090409 02o0ｸ7 02fi0402o0ｸ70ｹ0 0303000ｸ707 0ｹ0 & ﾞ0707apple020ｸ701090ｹ0 閨07o0ｹ0 07 鑰0ｸ7 08 03000702o0ｸ7 o08006ｧ903o0702 06 0402o 090009o07fi0ｹ0 fi0206 00fi07o 閨07 07 鑰 08070300 02o apple03o026ｦ0apple020006 applefi 020907 07 0207030ｸ76 709 10.000 03 040206020607 o0ｸ704060607, 0402o 0ｸ76 70903fi 02fi0402o0ｹ0 0906 0209 060001 090ｷ3096ｧ8 0203060706020607 00000300020607 02 06 0402o 0000090703o 0403o070602fi 060704020900 appleo0ｸ7 apple 0602006ｧ902 06 0906 020907 閨090203060409 020ｷ307 08 030007020ｷ307 applefi 02060ｹ0 0300fi 06000ｹ0 0304 閨0ｹ0. 05 appleo020003o6ｦ00400 0ｸ7apple0003 apple03o6ｦ00402000ｸ70409 000707 appleo 0604o0ｸ70000 0209 00006ｧ90ｷ30409 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 0400 閨07 07 00fi07o apple 030709o0702. ﾇ 6ﾑ80ｸ70306apple09 apple03o040003026ｦ00006 040ｸ707o03060207 030609fi020003000ｹ0 00apple0007 6ｦ00400060ｹ0 0400 0303000ｸ707 & ﾞ0707apple020ｸ70109 0400 0404 閨0409 0000 02060ｹ0 ﾇ09 ﾞ. 6ｾ4 ｯ 0ｸ702fi 040ｸ7006 50703o0ｸ707 o06 o0602o07o000602 閨0ｹ0 040ｸ707036ｧ802000ｹ0 02 06 o06 040ｸ707036ｧ802000ｹ0 0906 00apple0007 6ｦ00400060ｹ0, 02o apple0003066 5070303o07 apple 03o046ｧ80ｹ0 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0, o06 06 0602 046ｧ9000ｹ0 閨0902030604090ｹ0 02 06 0900070602fi020003 o06 02o06070ｷ3070602 閨0ｹ0 070206036ｧ86 700060ｹ0 0906 02060ｹ0 07 閨000ｹ0 02000407o03o096ｧ9000ｹ0. 00O06 04030007006ｧ90ｹ0 0402060ｹ0 ﾇ09 ﾞ 006ｧ907 06 apple03fi030ｸ700o06 07 040209036ｧ901o0ｸ707 020907 02 0607o02o006ｧ9 ｨC03 閨03o0ｸ707 07 0007090000030607o0702 06 02 06 07 appleo03 006 50707o0ｸ707 02 apple0300o070002026ｧ800 02 020ｷ307 07 閨0ｷ307 030003 apple0006060703 02o076ｧ9ｨB0006 o Sir Tom McKillop. 00O06 04030007006ｧ90ｹ0 04020907 6ﾑ80ｸ70306apple09 03 閨03o0ｸ707 07 閨04o0ｸ707 040209 06070300046ｧ8 02o0ｸ70ｹ0 apple0003060404fi020003000ｹ0 apple030903o08o036ｧ9000ｹ0 04040002060207 0000 02060ｹ0 030003 apple000ｸ7020602 閨0ｹ0 090ｷ309 閨0ｹ0. 05 閨03o0ｸ707 00apple6ｧ904090ｹ0 07 閨04o0ｸ707 000009 036ｦ002000309 040ｸ700000002o046ｧ8 0402o 040400 06 0400fi 02090ｹ0 appleo03060206026ｧ80ｹ0 0ｸ709006ｧ9 0ｹ0. 09 03fi03 0ｸ70207 09 6ﾑ80ｸ70306apple09 06040207ｨB0006 07 0ｸ706o0300026ｧ8040006 07 閨000ｹ0 02000407o03o096ｧ9000ｹ0 02 06 0007 006ｧ907 06 02fi0009 閨02o060009 07 0702060000020ｷ3apple6ｧ9040006 02060ｹ0 0203 閨04o0ｸ704000ｹ0 02 06 00000303o07020602 閨0ｹ0 07070902000ｹ0 apple00036ｧ903 036 7090ｹ0 02o0ｸ7 090903070402o0702o0ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ802o6ｦ0 apple0309030ｸ70400o6ｦ003. 6 6ｾ4f6ﾑ86ﾑ8 02006ｦ004o0ｹ0 47

13 ﾞ07 03000603090409 02090ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 03o00o0300046ｧ9 0ｹ0: 09 EFPIA 02 03006ｧ9 02 ﾒ03070209 09 閨0309 07 0806o0300026ｧ804o0ｸ707 閨07 02 07o070604020602fiapple03 6ｧ90406o apple 0902fi040006o0ｸ7 00apple06apple 陦o0ｸ7 0906 02 0607o02fi00 08070300 02 09030607 applefi 02o 6ｾ40ｸ7006 5o6ｦ00306o 08appleo0ｸ703090607 0809006ｧ9 0ｹ0 02090ｹ0 6ﾑ8.6ﾑ8. 09 EFPIA, 0402 apple03 6ｧ90406 02090ｹ0 縺000706026ｧ80ｹ0 02090ｹ0 6ｾ40ｸ707 閨03000ｸ704090ｹ0, o030907070ｷ30400 workshop 0000 03 閨00 020907 ﾞ07 03000603090409 02090ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 03o00o0300046ｧ9 0ｹ0. 00apple0ｷ30ｹ0 02o076ｧ90402090200, o06 026ｦ00306000ｹ0 apple03o020003 06fi020902000ｹ0 0906 020907 EFPIA 006ｧ907 06: 09 ﾇ apple03o0402 046ｧ9 020ｷ307 00 o00 閨070ｷ307: 09 O06 06 0602 046ｧ9000ｹ0 閨0902030604090ｹ0: 09 ﾇ 000ｸ7000306016ｧ9 020ｷ307 00apple06040006036ｧ804000ｷ307: 09 ﾇ 02 0300 02o00apple 09036ｦ0apple07090409: 09 EFPIA 0ｸ7appleo040209036ｧ9ｨB0006 10+1 0403fi0706 apple03o0402 046ｧ9 0ｹ0 020ｷ307 00 o00 閨070ｷ307. ﾞ0ｸ702fi 03 appleo020003 閨040006 006ｧ9 o0ｸ70406 040206026ｧ8 6ｦ007 0009 appleo0ｸ7 03 o 09096ｧ8040006 020907 閨03000ｸ707 04020907 6ﾑ80ｸ70306apple09. 09 EFPIA 0ｸ7appleo040209036ｧ9ｨB0006 6 500030206060400060ｹ0 appleo0ｸ7 03 06 0408 036ｧ904o0ｸ707 閨07 0ｸ707 02fi 02 06 appleo020003000400 020602fi 6ﾑ8096ﾑ8 ﾞ/ ﾒ0007020306026ｧ8 06 0602 046ｧ9, 0400 040ｸ707 0ｸ7 0400fi 6 50003-0206060400060ｹ0 appleo0ｸ7 03 06000ｸ702o036ｦ007o0ｸ707 02060ｹ0 00apple06040006030900 020602 閨0ｹ0 03 0402090306fi020902000ｹ0. 09 EFPIA 0ｸ7appleo040209036ｧ9ｨB0006 0209 07o00o0300046ｧ9 appleo0ｸ7 06000ｸ702o036ｦ0070006 02060ｹ0 00apple06040006030900 0206-02 閨0ｹ0 03 0402090306fi020902000ｹ0. 09 EFPIA 0ｸ7appleo040209036ｧ9ｨB0006 閨0702o07 020907 0007 0ｸ70707000ｷ30409 02090ｹ0 02o0ｸ7 040ｸ704026ｧ800 02o0ｹ0 08 0300 02o00apple 09036ｦ0apple070904090ｹ0. 09 ﾇ apple03o04020603 閨00000709 030003 apple000ｸ70206026ｧ8 016ｧ9 : 09 EFPIA apple060402006ｦ00006 fi0206 09 000604 090ｷ3096ｧ8 02o0ｸ7 fi03o0ｸ7 0ｷ30ｹ0 0203060209036ｧ9o0ｸ7 0906 020907 閨090203060409 0007fi0ｹ0 apple03o0ｸ8fi0702o0ｹ0 03 006ｧ90400 030709020602 閨0ｹ0 040ｸ707 鐶pple0006000ｹ0 040209 0900fi0406 0ｸ709006ｧ9. 09 O06 apple030903o08o036ｧ9000ｹ0 apple03o0ｹ0 02o07 040300076ｧ8: 09 EFPIA 02 030ｷ304o036ｧ9ｨB0006 02 6 56ｧ800 02 appleo0ｸ7 03 00apple060203 閨6 7o0ｸ707 0402o0ｸ70ｹ0 04030007006ｧ90ｹ0 02 06 02o0ｸ70ｹ0 02 02 07 030ｷ302 閨0ｹ0 020907 apple03fi046 5 0409 0400 apple030903o08o036ｧ9000ｹ0 0906 02 08070300 02. 6ｾ40ｸ7006 5o6ｦ00306o 08appleo0ｸ703090607 0809006ｧ9 0ｹ0 2 ｦﾐo0ｸ7076ｧ9o0ｸ7 2003 ﾒ 0207 020907 046ｦ00402006 709 020ｷ307 08appleo0ｸ703090607 0809006ｧ9 0ｹ0 02090ｹ0 6ﾑ8.6ﾑ8. 04020907 oappleo6ｧ9 040ｸ700000002006ｧ904 07 02 06 o06 08appleo0ｸ70309o6ｧ9 020ｷ307 0ｸ7applefi 閨0702 0109 040ｷ3030607, 0402060ｹ0 2 ｦﾐo0ｸ7076ｧ9o0ｸ7 2003 0402o o0ｸ70100006 5o6ｦ00309o 00apple0002006ｦ0040309 00appleo03060206026ｧ8 040ｸ700080ｷ3076ｧ9 03 00apple6ｧ9 020ｷ307 07o00o03000206020607 02000600 閨070ｷ307 02o0ｸ7 00 ﾒ 07o07060400o6ｦ003 02 06 02090ｹ0 00O 09096ｧ9 0ｹ0 0906 02 08070300 02 0906 07030306apple060709 04036ｧ8040903. 6ｾ402060ｹ0 25 ｦﾐ080ｸ7076ｧ9080ｸ7 09 6ﾑ80303090706026ｧ8 09030800 036ｧ9 08030802036ｧ8030ｷ30400 020907 ｰapple0803060206026ｧ8 040ｸ700080ｷ3076ｧ9 ｱ 02 06 04020907 08 09096ｧ9 0906 02 ﾒ02090706 0203060207 08070300 02. O 00apple6ｧ90203oappleo0ｹ0 02. Erkii Liikanen 02 06 o06 08appleo0ｸ70309o6ｧ9 0809006ｧ9 0ｹ0 fi030ｷ307 020ｷ307 040ｷ3030607 040ｸ707000407030904 07 020907 6ﾑ80303090706026ｧ8 0903o00 036ｧ9 02 06 0006 060207 02o07 apple03o00 03006ｦ0o0702 08appleo0ｸ70309fi 02. ﾒ060402 6ｾ4020008 076ｧ8 0906 020907 apple03o04apple07030006 appleo0ｸ7 02 02006 5036ｧ80309 0400 fi03 02 00apple6ｧ9apple00 020ｷ307 000309 04060607 0000 0402oapplefi 020907 090006o0ｸ703096ｧ9 02090ｹ0 o03o020309030ｷ300 閨07090ｹ0 apple03fi02 04090ｹ0 appleo0ｸ7 02 02 02 閨03090200 0906 020907 appleo03060206026ｧ8 040ｸ700080ｷ3076ｧ9. ﾇ apple03o00 036ｧ9 02090ｹ0 o0007 0ｹ0 000309 046ｧ9 0ｹ0 02o0ｸ7 6ｾ40ｸ7006 5o0ｸ7036ｧ9o0ｸ7 閨09060700 applefi 020907 0406000ｸ7036ｦ007020306 040900o046ｧ90ｷ307 6ｾ404 閨04000ｷ307 02o0ｸ7 6ﾑ8O02 02. ﾒ 0200036ｧ907 090ｷ303 0ｹ10209. 02006ｦ004o0ｹ0 47 6ｾ4f6ﾑ86ﾑ8 7

13EFPIA ANNUAL MEETINGS ATHENS 2003 08 04060207 040900006ｧ9 040ｸ700080ｷ3076ｧ9 0ｹ0: 1. 0900 6ｧ9o 0008 0300o096ｧ80ｹ0 ﾒ 07o07060400o6ｦ0 6ﾒ2o 6ｾ40ｸ7006 5o6ｦ00306o 040ｸ700080607090400 0906 020907 00apple 閨0202 0409 02090ｹ0 0ｸ7appleo0403000ｷ30206026ｧ80ｹ0 0200-07020306026ｧ80ｹ0 06 0602 046ｧ9 0ｹ0 閨0902030604090ｹ0 08 030007020ｷ307 (02o0607o0206026ｧ8 07 0006 ) 0906 07030306apple060709 04036ｧ80409, 000202fi0ｹ0 020ｷ307 6 506o02000407o03o0906020607 02 06 0400 0002006ｧ907 02 oappleo6ｧ9 閨04o0ｸ707 閨07 00060109 0906 020907 07020600000206apple060409 020ｷ307 0403000700060607: ﾞｦﾐDS, ﾒ 03026ｧ907o0ｸ7, 03000ｸ703o0002080ｸ70306040206020607 06 02 03 040607 02 06 0406 6 56ｧ80209. 縺06 02 08070300 02 0703030ｷ307 030003 apple000ｸ70206020607 02 020909o03060607 03 apple 03 00006ｧ9070006 09 0ｸ707 02fi020902 00apple0603o096ｧ80ｹ0 000002 016ｦ0 ﾒ0007020306026ｧ80ｹ0 02 06 ﾞappleo02000702030ｷ300 閨07090ｹ0 0406 0602 046ｧ9 0ｹ0. 6ﾑ8apple6ｧ904090ｹ0 閨09060700 02-02 07o0902fi fi0206 02 06 070303000ｹ0 00apple06apple03 鑰07 030003 apple000ｸ7020602 閨0ｹ0 02 020909o036ｧ9000ｹ0 03 apple03o04020003o6ｦ007 00000207 applefi 0106o03fi09090409, 04020907 0ｸ7appleo0403000ｷ30206026ｧ8 ﾒ0007020306026ｧ8 06-0602 046ｧ9 0402o 00 閨0303o07. 2. 0903o0402 046ｧ9 00 o00 閨070ｷ307 09 6ﾒ2o 6ｾ40ｸ7006 5o6ｦ00306o 040ｸ700080607090400 0906 1000026ｧ8 apple03o0402 046ｧ9 00 o00 閨070ｷ307 0906 fi03 02 08070300 02 appleo0ｸ7 000902036ｧ907o0702 06 0000 0ｸ7appleo0403000ｷ30206026ｧ8 020007020306026ｧ8 06-0602 046ｧ9. 09 縺06 fi03 02 070303 08070300 02 0906 02 oappleo6ｧ9 03 0604046ｦ00006 09 apple03o 0603000206026ｧ8 06 0602 046ｧ9 02o 6ｾ40ｸ7006 5o6ｦ00306o 040ｸ700080607090400 0000 020907 0ｸ707 02fi020902 apple03o0402 046ｧ9 0ｹ0 00 o00 閨070ｷ307 0906 10 0403fi0706, 030307 0906 02 090007fi040900 08070300 02 07 00appleo03006ｧ9 07 02 02 026ｧ9030002 06 6ｧ902090409 閨0902030604090ｹ0 00000207 applefi 8 0403fi0706. 6ﾒ2 090007fi040900 08070300 02 fi000ｷ30ｹ0 0007 03 020ｸ70203o08o03o6ｦ007 04020907 09o0307 apple030607 020907 apple 03 閨03000ｸ70409 02090ｹ0 1000026ｧ9 0ｹ0. 6ﾒ2o 6ｾ40ｸ7006 5o6ｦ00306o 040ｸ700080607090400 07 0ｸ7appleo040209036ｧ9010006 1 00apple06apple03fi04030002o 0403fi07o apple03o0402 046ｧ9 0ｹ0 00 o00 閨070ｷ307, fiapple0ｷ30ｹ0 006ｧ90400 apple03o02 03006ｧ9 applefi 020907 6ﾑ8apple060203oapple6ｧ8, 0906 040900 07020602 閨0ｹ0 07 閨000ｹ0 0007 006ｧ90100060ｹ0, 030307 00fi07o 0906 02 apple03o0ｸ8fi0702 0000 0ｸ7appleo040300-0ｷ30206026ｧ8 020907 ﾒ0007020306026ｧ8 0406 0602 046ｧ9. ﾇ applefi08 0409 02o0ｸ7 6ｾ40ｸ7006 5o0ｸ7036ｧ9o0ｸ7 07 000907 apple03o0408 閨030006 apple 03fi00o06 apple03o0402 046ｧ9 00 o00 閨070ｷ307 0906 040900 07020602 閨0ｹ0 07 閨000ｹ0 0007 006ｧ90100060ｹ0 0400 070303000ｹ0 0403 閨070006000ｹ0 0007 006ｧ907 06 03o0906026ｧ8 02 06 0007 apple 03 閨040006 0ｸ7appleo04026ｧ803060109 0906 apple0003 0602 閨030ｷ3 閨03000ｸ707 04 ｯ 0ｸ702 閨0ｹ0 02060ｹ0 apple000306o04 閨0ｹ0. 6ﾑ807 020ｷ3 000002 016ｦ0, o06 0ｸ7applefi 閨0702 0109 040603000ｹ0 閨04o0ｸ707 03046ｧ9040006 006ｧ9 06 0602 046ｧ9 apple03o02000600 閨07o0ｸ7 07 02 030600030604o0ｸ707 02 6 0403fi0706 0400 fi0309 020907 02o0607fi020902. 6ﾑ8applefi000007 6 56ｧ800 02 6ﾒ2o Priority Action Team (PAT) Future Medicines Legislation (FML) 02090ｹ0 EFPIA 03 apple 03 02o03o0ｸ703006ｧ9 07 030ｸ702060207 02 0300apple02o0000036ｧ8 020003060207 02006ｧ90000-07 02 06 02 040ｸ700apple0003070400 0207 02o0ｸ70ｹ0 appleo0ｸ7 03 appleo0402 03o6ｦ007 0402o 6ｾ40ｸ7006 5o6ｦ00306o 02 06 0402o HAC. 6ｾ400 0ｸ7026ｧ8 0209 08070409 0403000607ｨB0002 06 07 0002o0600 0402o6ｦ00000 0906 0209 006ｦ002000309 070709070ｷ30409 0402o 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi ﾒo0607o6 5o6ｦ00306o 02 06 00000207 0402o 6ｾ40ｸ700-6 5o6ｦ00306o. ﾇ 0707090209 07 apple06 閨04o0ｸ70000 0906 020907 o03o02036ｧ8030ｷ30409 02090ｹ0 ﾞ07 030006-030904090ｹ0 02090ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 03o00o0300046ｧ9 0ｹ0 apple030607 applefi 0209 0406006ｦ0030ｸ7070409 02o0ｸ7 2004, 040ｸ70700046ｧ9ｨB0006 07 006ｧ907 06 appleo036ｦ0 040900 07020602fi 03 閨00. 6ｾ402 040ｸ7o03fi09090409 020ｷ307 0700o02 閨030ｷ307 0402o0604006ｧ90ｷ307 00apple6ｧ9 02o0ｸ7 03 閨00 02o0ｹ0 02. 09. 09 0402o03070209 ﾇead of Regulatory Affairs Pfizer Hellas. 8 6ｾ4f6ﾑ86ﾑ8 02006ｦ004o0ｹ0 47

136ｾ40ｸ707 陦030608 ｰ ﾇ 6ﾑ80ｸ70306apple09 02090ｹ0 080900 6ｾ40ｸ707 陦030608 ｰ ﾇ 6ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ0: 03 閨000ｹ0 6ﾑ803000ｸ70300036ｧ9000ｹ0 0906 02080ｸ70ｹ0 04030007006ｧ90ｹ0 02080ｸ7 046ｧ8000003 ｱ 03 閨000ｹ0 6ﾑ803000ｸ70300036ｧ9000ｹ0 0906 02080ｸ70ｹ0 04 07006ｧ90ｹ0 02080ｸ7 046ｧ8000003 ｱ 01 06030002060400fi0ｹ0 02080ｸ7 6ﾑ8apple06026ｧ900080ｸ7 090308 陦03080ｸ7 02080ｸ7 6ｾ4026ﾑ86ﾑ8 0403.. ﾒ03 04070309 6ﾑ86ｧ907 06 apple03070900 0206 000009070309 0206006ｧ8 07 apple000ｸ7036ｦ007o00 06 0402o0ｸ70ｹ0 02o030ｸ708 6ｧ9o0ｸ70ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02 0300 02o6 506o000904 076ｧ9 0ｹ0. 6ﾑ802 00 閨03o0ｸ70ｹ0 02o0ｸ7 04.6ｾ4. 02 06 020ｷ307 0000030607 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 04 0ｹ0 02 030ｷ304o036ｧ9ｨB0ｷ3 04020907 040603 00 0ｹ0 02 06 04 0ｹ0 006ｦ004o00 06 02 036ｧ8 06 00o076ｧ8. 6ﾑ86ｧ9000003 000ｸ7020ｸ704006ｧ90ｹ0 02 06 0ｸ7apple00036ｧ808 07o06 appleo0ｸ7 080603o010007o6ｦ00000 04020907 040603 00 0ｹ0 020907 00026ｧ80406 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ70409 02 06 0209 040ｸ70700 036ｧ9 0409 02090ｹ0 EFPIA, 02090ｹ0 040ｸ707o00o04appleo07 6ｧ9 0ｹ0 00 0ｹ0 appleo0ｸ7 040ｸ700apple03090306-070006 08 閨02o0ｹ0 25 0403fi0706 applefi 02090ｹ0 090006o0ｸ703096ｧ9 02090ｹ0 02 06 006ｧ9000003 6 5 閨6 5 06o06 fi0206 o06 040ｸ7ｨB09026ｧ80400060ｹ0 02 06 09 0702 0303 096ｧ8 applefi6 7000ｷ307 02 0207 020907 060703020006 020ｷ307 040ｸ70700 03060704000ｷ307 03 o 09096ｧ804o0ｸ707 0400 0300020602 閨0ｹ0 00060409096ｧ80400060ｹ0 appleo0ｸ7 03 040ｸ7006 5070303o0ｸ707 04020907 6ｧ9 030ｸ70409 02090ｹ0 006ﾑ80ｸ70306apple090ｹ0 02090ｹ0 0809006ｧ9 0ｹ003 appleo0ｸ7 apple03 0900 0206ｨBfi000003. O 6ｾ4026ﾑ86ﾑ8 040ｸ700apple03090306070006 00apple6ｧ904090ｹ0 20 0403fi0706 04 07 00 閨03o0ｹ0 02090ｹ0 EFPIA. 6ﾒ2o 1981 0ｸ7apple6ｧ80304 07 04020907 6ﾑ8030307 02 閨04040003060ｹ0 046ｦ007 000400o06 appleo0ｸ7 0002apple03o040ｷ3appleo6ｦ004 07 0000090703o0ｸ70ｹ0 08 0300 02o6 506o006ｧ804 07o0ｸ70ｹ0, 02o0ｸ70ｹ0 00060203o6ｦ00ｹ0 08 0300 02o6 506o006ｧ804 07o0ｸ70ｹ0, 02o0ｸ70ｹ0 070206apple03o0406appleo0ｸ70ｹ0, 02o0ｸ70ｹ0 000604 090ｷ309006ｧ90ｹ0 06 07o00006ｧ90ｹ0. ﾒ 07006ｧ90ｹ0 applefi 0ｸ702o6ｦ00ｹ0 02o0ｸ7 040ｸ707 閨0400o0ｸ70ｹ0 0007 00appleo03o6ｦ00400 07 096ｧ9070006 00 閨03o0ｹ0 02090ｹ0 EFPIA 0906 026ｧ9 0007 0002apple03o040ｷ3appleo6ｦ00400 020907 apple030006o6 709086ｧ9 02090ｹ0 09o03070ｹ0 appleo0ｸ7 6ｧ802 07 apple 03 6ｧ902090209 apple03o00applefi03000409 02 06 02fi0200 00036ｧ8080309 09 applefi08 0409 02090ｹ0 00040ｸ709040607000ｸ704090ｹ003 020ｷ307 000009 036ｦ00200030ｷ307 02fi0200 040ｸ707 閨04000ｷ307 02 06 09 090006o0ｸ703096ｧ9 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 appleo0ｸ7 02o 1983 閨09060700 000202fi0ｹ0 04 07 00 閨03o0ｹ0 02090ｹ0 EFPIA. ﾞ0ｸ7026ｧ8 09 026ｧ907090409 0ｸ7apple6ｧ8030100 02o appleo08 040604020602fi 070300 020ｷ307 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 04020907 6ﾑ8030307. 6ﾒ2 00 閨0309 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02 036ｦ0apple02o0ｸ707 046ｧ8000003 02o 90% 02090ｹ0 08 03-00 02000ｸ70206026ｧ80ｹ0 09o03070ｹ0 000706 o 6ｾ4026ﾑ86ﾑ8 閨040006 02 030600030ｷ303006ｧ9 04 07 040ｸ707o00060309026ｧ80ｹ0 0000 020907 ﾒ0ｸ76 5 閨0307090409. 6ｾ402 22 0403fi0706 03 0402090306fi020902 0ｹ0 02o0ｸ7 030307 020ｸ7036ｧ90ｷ30ｹ0 02 apple 閨070200 020003000ｸ702 6ｧ9, o 6ｾ4026ﾑ86ﾑ8 06 040006036ｧ90403090200 appleo0303 閨0ｹ0 00006ｧ9ｨBo07000ｹ0 02036ｧ90400060ｹ0 04020907 6ﾑ8030307 02 06 02 02fi03030ｷ30400 0000 020907 appleo036ｦ002060009 040ｸ7006 5o036ｧ8 02 06 0ｸ7appleo04026ｧ803060109 02090ｹ0 EFPIA 07 0409000006060400060ｹ0 0000030602 閨0ｹ0 00apple06020ｸ7046ｧ9000ｹ0. 0900 020907 000ｸ702 06036ｧ9 02090ｹ0 apple 03o0ｸ7046ｧ9 0ｹ0 04 0ｹ0 04020907 6ﾑ8030307, 00apple060203 閨6 70200 00o0ｸ7 07 04 0ｹ0 00070900000306040ｷ3 046ｦ00702o00 0906 020907 6ﾑ80303090706026ｧ8 02 0300 02000ｸ70206026ｧ8 ﾞ09o0307. 6ｾ4 07 09o0307 006ｧ907 06 0302000207 0007 06 08 閨03o0ｸ704 0906 0006 000602036ｧ8 040603 020ｷ307 10 0002 02o00000ｸ7036ｧ90ｷ307 02 02o6ｧ9020ｷ307. ﾇ 040ｸ707o0306026ｧ8 09o0307 0400 020600 閨0ｹ0 000309o0402 046ｧ9o0ｸ7 076ｧ8030300 02o 2002 0400 2,6 060ｹ0 6ﾑ80ｸ70306 apple 03o0ｸ7040607ｨBo0702 0ｹ0 6ｦ001090409 02 020003000ｸ702 6ｧ9 apple 閨070200 0403fi0706, 6ｧ802 07 apple00036ｧ9appleo0ｸ7 20%. 00000ｷ30ｹ0 6 503060402fi00 040200 040ｸ7070004060ｹ0 00apple03o040207 0400 0000090703 03 閨00 02 appleo0ｸ7 apple03o04apple 03o6ｦ00000 07 036ｦ004o0ｸ70000. 6ｾ4 ｯ 0ｸ702fi 02o 040900006ｧ9o 03 閨030ｷ3 07 02o076ｧ9040ｷ3 020907 040900 07020602fi02 0209 6 5o6ｧ8030006 appleo0ｸ7 00 0ｹ0 apple 03 閨040006 02o 0903 08006ｧ9o 02090ｹ0 EFPIA 0402060ｹ0 08030ｸ701 閨0303000ｹ0 02 06 07 000ｸ704 030604026ｧ8040ｷ3 020907 o0007 02o0ｸ7 Brian Ager 02 06 06 06 6ｧ9020003 02090ｹ0 Marie-Claire Pickaert, 02o 07o000602fi 02006ｧ800 appleo0ｸ7 06000ｸ7036ｦ0070006 09 Ann Robins 02 06 fi03o 02o apple03o040ｷ3apple0602fi 0906 020907 02 036ｧ8 040ｸ707000309 046ｧ9 02 06 0ｸ7appleo04026ｧ803060109. 02006ｦ004o0ｹ0 47 6ｾ4f6ﾑ86ﾑ8 9

13EFPIA ANNUAL MEETINGS ATHENS 2003 01070309 0402060ｹ0 040ｸ70702o07060400 閨07000ｹ0 0007 閨03090006000ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02 06 02090ｹ0 EFPIA 02 02o03030604 0000 07 apple006ｧ904o0ｸ70000 020907 02oapple06026ｧ8 06o6ｧ902090409 07 0008 0300fi040006 04020907 6ﾑ8030307 apple03006ｧ90402000ｹ0 o 09096ｧ9000ｹ0 02090ｹ0 6ﾑ8.6ﾑ8, appleo0ｸ7 o036ｧ9ｨbo0ｸ707 02060ｹ0 apple03o030004006ｧ9000ｹ0 0906 020907 閨090203060409 020ｷ307 0206000607 02 06 020907 036ｧ90402. 0900 040ｸ707 陦0306 02 06 090000036ｧ9 000ｹ0 appleo0ｸ7 o0309 070604 0700 04020907 6ﾑ8030307 0402 oappleo6ｧ9 09 Marie Claire Pickaert & o Phillip Elsworth 6ｧ802 07 026ｦ00306o06 o0006030902 閨0ｹ0, 000ｸ7 0604030902oappleo066ｧ804 0000 02o0ｸ70ｹ0 appleo0306020602o6ｦ00ｹ0 00 0ｹ0 0906 020907 0707090209 閨0902 0603090ｹ0 apple03fi046 5 04090ｹ0 020ｷ307 040300070607 0402060ｹ0 07 閨000ｹ0 030003 apple006ｧ9000ｹ0. 0900 0ｸ702fi 02o07 0203fiappleo 060403 07fi00 040200 fi0206 6 5o09036ｧ804 0000 020ｷ307 040603 00 0ｹ0 07 apple03o040ｷ3036ｧ8040006 閨07 6 56ｧ800 apple06o 02o070207 0402060ｹ0 apple03o02036ｧ80400060ｹ0 02o0ｸ7 07 鑰0ｸ7 apple0003066 5070303o0702o0ｹ0 appleo0ｸ7 090006o0ｸ70309006ｧ9 04020907 6ﾑ80ｸ70306apple09, 09 006ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ003. 09 03 ｯ fi03 0ｸ70207, fi0206 閨09060700 0007 006ｧ907 06 03020002fi. ﾇ 02 0300 02o6 506o000904 076ｧ9 0ｸ7appleo040300o6ｦ002 06 02fi00 07 006ｧ907 06 07 0902 040206026ｧ8 04o030909fi0ｹ0 02090ｹ0 6ﾑ80303090706026ｧ80ｹ0 O0602o07o006ｧ9 0ｹ0 0000 00 0203oapple03fi03000400 07070006 6ｦ06 7o0ｸ70ｹ0 500 0002 02. 6ﾑ80ｸ70306, appleo04fi appleo0ｸ7 070206apple03o040ｷ3apple006ｦ00006 02 0403 閨09 020ｷ307 0203 0206020607 07o04o02o00006ｧ90ｷ307 apple03o0ｹ0 020907 6 506o000904 076ｧ9, 000706 o06 0900 閨03000ｹ0 apple6ｧ904020ｷ304090ｹ0 0100apple000307o6ｦ007 02060ｹ0 360. 00apple0ｷ30ｹ0 09070ｷ3036ｧ9ｨB000200 fi03o06 o06 046ｦ00700 03o06, 09 6ﾑ8030307 006ｧ907 06 09 026ｦ00306 apple09096ｧ8 apple 03 03036ｧ8030ｷ307 000604 090ｷ3090607 0402060ｹ0 040603000ｹ0 04 0ｹ0 03fi090ｷ3 02090ｹ0 04 0009036ｧ80ｹ0 0206006ｧ80ｹ0 08 030007020ｷ307 04020907 6ﾑ8030307 appleo0ｸ7 00apple066 5036ｧ803090200 02o 1997 0000 08appleo0ｸ7030906026ｧ8 ﾞapplefi08 0409 appleo0ｸ7 apple03fi0408 02 0700020307apple09 applefi 02o 6ｾ40ｸ7006 5o6ｦ00306o 02090ｹ0 6ﾑ8apple060203 02006ｧ9 0ｹ0 00000207 applefi apple03o04080ｸ7096ｧ8 02o0ｸ7 6ｾ4026ﾑ86ﾑ8. 6ﾒ2o 2001 02o 046ｦ007o03o 020ｷ307 apple 0307030309030ｷ307 0001 090ｷ3090607 applefi 020907 6ﾑ8030307 0ｸ7appleo03o096ｧ9ｨB0002 06 0400 396 0002 02. 6ﾑ80ｸ70306. 6ﾒ2 0402o0604006ｧ9 0906 02o 2002 0007 閨04o0ｸ707 o030604020602oappleo060903006ｧ9 02fi0009 030307 0ｸ7apple070304o0ｸ707 0007 006ｧ90100060ｹ0 fi0206 o06 apple03o04 0300o09 閨0ｹ0 020ｷ307 0206000607 00000306020607 08 030007020ｷ307 appleo0ｸ7 00apple 閨020ｸ70400 o 6ｾ4026ﾑ86ﾑ8 02o07 apple0003 0400 閨07o 0403fi07o 00000207 applefi apple000702 0002 閨0ｹ0 apple07090ｷ300, 00apple0903 陦 04 07 0207apple0ｷ30ｹ0 02060ｹ0 apple 030703030903000ｹ0 0001 090ｷ309 閨0ｹ0. 6ﾑ803apple6ｧ9ｨBo0ｸ70000 apple0ｷ30ｹ0 09 040ｸ707 閨04060409 020ｷ307 apple03o04 0300o090607 020ｷ307 0206000607 03 0207006 70006 0ｸ7026ｧ8 0209 03 0402090306fi020902 appleo0ｸ7 006ｧ907 06 00060ｹ0 6 50703o0ｹ0 020ｷ307 0003036ｧ8070ｷ307 06 02030607 02 06 040300070607 06fi0206: ) o06 04030007006ｧ90ｹ0 04020003o6ｦ00702 06 02 08070300 0207 02o0ｸ70ｹ0 appleo0ｸ7 00apple 0700010709o0702 06 02 06 6 5) 02 07 陦 08070300 02 0007 03 06 020003o6ｦ007 appleo02 04020907 6ﾑ80303090706026ｧ8 09o0307, 0402060ｹ0 00060203 閨0ｹ0 020600 閨0ｹ0 appleo0ｸ7 apple 0602o6ｦ00702 06 0906 07 apple00030603090803o6ｦ007 04020907 036ｧ90402, appleo0ｸ7 03 apple03o02 03 閨040006 02o 08 0607fi- 000007o 02o0ｸ7 0702fi000607o (domino effect) 0402060ｹ0 070303000ｹ0 09o03 閨0ｹ0 06 6ｧ90ｷ30ｹ0 020ｷ307 0ｸ7applefi 閨0702 0109 040ｷ3-030607, 04020907 06000ｸ7030ｸ700 閨0709 6ﾑ80ｸ70306apple09. 6ﾑ86ｧ9000003 060406fi o01o06 fi0206 o06 apple03o02070400060ｹ0 02090ｹ0 o0007 o0ｹ0 G10 03 6 5000302060604o0ｸ707 030907 6ｧ8 09036ｧ809o03 020907 000602fi07 02090ｹ0 09o03070ｹ0 02 06 04020907 6ﾑ8030307. 6ﾑ8apple06 6ｧ90ｷ30109 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 006ｧ907 06 0ｸ702fi 07 096ｧ9070006 09036ｧ809o03 02 06 fi0406 030907. ﾒ6ｦ0030600 08appleo0ｸ70309, 09 6ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ0 o0602o o00006ｧ902 06 02 06 09 6ﾑ8030307 0ｸ7appleo040300o6ｦ002 06 07 0702 appleo02030603006ｧ9 0402060ｹ0 apple03o04 o026ｧ9000ｹ0 020ｷ307 02o0607o0206020607 02090ｹ0 0002 6ｧ9030ｷ307. ﾞ030306060ｹ0 fi03o06 o06 0303030907000ｹ0 03-0307 02 06 fi03o06 o06 6ﾑ80ｸ7030ｷ3apple 6ｧ9o06 appleo0ｸ7 03 00apple0603 閨01o0ｸ707 07 apple00030704o0ｸ707 02060ｹ0 06 02oapple 閨0ｹ0 02o0ｸ7 04020907 6ﾑ8030307 0007 03 6 503o0ｸ707 02o 07 000007fi000007o 00apple6ｧ9apple00 o 030003 apple006ｧ9 0ｹ0 02 06 0ｸ702fi 03 006ｧ907 06 apple 0307 000202o. 縺070ｷ3036ｧ9ｨBo0ｸ70000 fi0206 0004006ｧ90ｹ0 02 06 o06 040ｸ7070003090702000ｹ0 04 0ｹ0 apple 03 02o03o0ｸ703006ｧ90200 applefi 02o070207 02060ｹ0 040ｸ7ｨB09026ｧ8-0400060ｹ0 02090ｹ0 o0007 o0ｹ0 G10 02 06 006ｧ900 040200 6 5 閨6 5 06o06 apple0ｷ30ｹ0 02060ｹ0 apple03o02070400060ｹ0 appleo0ｸ7 03 apple03o026ｦ06 7o0ｸ707 03 02060ｹ0 00000300026ｧ804000200, 03 02060ｹ0 0ｸ706o0300026ｧ804000200 02 06 000ｸ70003apple060402o6ｦ00000 fi0206 03 02060ｹ0 0008 0300fi04000200. 10 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

130406006ｦ0030ｸ7070409 0406006ｦ0030ｸ7070409 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0 02 06 0809006ｧ9 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0 02 06 0809006ｧ9 O0006036ｧ9 02o0ｸ7 ﾒ 03. ﾒ. 6ｾ4020008 076ｧ8 08appleo0ｸ70309086ｦ0 0809006ｧ9 0ｹ0 02 06 0903fi07o06 0ｹ0 09000207 02060ｹ0 03 00 020602 閨0ｹ0 09000ｷ3appleo0306020602 閨0ｹ0 0303 09 閨0ｹ0 02090ｹ0 0002 00026ｧ9 0ｹ0 02o0ｸ7 ｯ90 0402060ｹ0 040603000ｹ0 02090ｹ0 ﾒ00-07020306026ｧ80ｹ0 02 06 ﾞ07 02o0306026ｧ80ｹ0 6ﾑ80ｸ70306apple090ｹ0 040900000606030902 07 000ｸ703006ｧ9 0ｹ0 02036ｧ900 02 0ｹ0 000002 04040900 02060400o6ｧ9 04020907 02o06070ｷ30706026ｧ8 02 06 o0602o07o0006026ｧ8 ｨB0ｷ36ｧ8. ﾇ 000002076 5 0409 applefi 02060ｹ0 o0602o07o006ｧ9000ｹ0 02000702030602o6ｦ0 040400-06 0400o6ｦ0 0402060ｹ0 o0602o07o006ｧ9000ｹ0 02090ｹ0 09o03070ｹ0 apple03o020703000400 0304060207 apple 030607 03fi00090409 ｨC 0400 0000030602 閨0ｹ0 040603000ｹ0 ｨC 02 06 040209 040ｸ707 閨040006 apple036ｧ80309 07 06o030907070ｷ30409 02o0ｸ7 02o06070ｷ3070602o6ｦ0 02 06 o0602o07o000602o6ｦ0 040ｸ7-04026ｧ800 02o0ｹ0. ﾇ 02 02070402 0409 0ｸ7026ｧ8 00apple 陦03 0400 04020907 0ｸ709006ｧ9, 02o 0ｸ7090006o07o000602fi 046ｦ004020900 02 06 020907 appleo03060206026ｧ8 0ｸ709006ｧ9 0ｹ0. 6ｾ402060ｹ0 040603000ｹ0 CEE apple 03 020903006ｧ902 06 閨07 0ｹ0 040900 07020602fi0ｹ0 03060300fi0ｹ0 apple03o6 503090007020ｷ307 0400 046ｦ0090203060409 0000 02060ｹ0 040603000ｹ0 02090ｹ0 6ﾑ8.6ﾑ8. 02 06 0006 0602fi020003 : 09 0000090703000ｹ0 00060403o 閨0ｹ0 0400 000003060207 000009 閨0309 02o0ｸ7 0ｸ7090006o07o000602o6ｦ0 02o00 陦, 020ｸ7036ｧ90ｷ30ｹ0 0400 07o04o02o000006 02 閨0ｹ0 02036ｧ907000ｹ0 02 06 000ｸ7020003000ｸ7fi07020ｷ30ｹ0 0402o07 03060300fi 020ｷ307 0906 02030607 09 0ｸ7apple0003040ｸ70902 閨0702030ｷ30409 040209 06o6ｧ902090409 02o0ｸ7 040ｸ704026ｧ800 02o0ｹ0 0ｸ709006ｧ9 0ｹ0 09 0ｸ7appleoapple03o0408o0307 02 06 0707060409 02 02 07o006ｧ8 0ｸ76 709036ｧ80ｹ0 02000407o03o096ｧ9 0ｹ0 02 06 08 030007020ｷ307 09 04 0009036ｧ8 0702 appleo020306040600fi020902 0402060ｹ0 apple03o04 o026ｧ9000ｹ0 020ｷ307 04030904020607 09 000602036ｧ8 appleo020003000400 020602fi020902 020ｷ307 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0 縺06 020907 07020600000206apple060409 02 06 036ｦ00409 020ｷ307 apple03o6 503090007020ｷ307 0006 07 陦 040203 02090906026ｧ8 07 040ｸ7090203fi020904090ｹ0 02o0ｸ7 0ｸ7090006o07o000602o6ｦ0 02o00 陦 閨040006 07 apple020ｸ70403006ｧ9 applefi 02060ｹ0 0304 閨0ｹ0 02090ｹ0 0002 00026ｧ9 0ｹ0 02o0ｸ7 ｯ90, 09 oappleo6ｧ9 apple00030603 006 507070006 020ｸ7036ｧ90ｷ30ｹ0: 09 0209 000002076 5 0409 applefi 02o 0203 020602fi 046ｦ004020900 026ｦ0appleo0ｸ7 Semasko 04020907 000604 090ｷ3096ｧ8 02090ｹ0 02o06070ｷ30706026ｧ80ｹ0 040807030604090ｹ0 026ｦ0appleo0ｸ7 Bismark, 0000 060708o03o0ｸ70ｹ0 o0309 070ｷ3020602o6ｦ00ｹ0 026ｦ0appleo0ｸ70ｹ0 09 020907 appleo02 閨0702030ｷ30409 040209 036ｧ86 709 appleo080704000ｷ307 0400 apple0003060800030006 02 閨0ｹ0 02 06 02oapple0602 閨0ｹ0 0304 閨0ｹ0 09 0209 00000306026ｧ8 06 060ｷ3020602oappleo6ｧ9090409 0ｸ7apple09030004060607, 020ｸ7036ｧ90ｷ30ｹ0 04020907 apple030ｷ302o6 507030006 apple00036ｧ903 036 709 (06 0203006ｧ9 ) 02 06 0402 08 0300 02006ｧ9 030307 02 06 0400 00060203fi 00 閨03o0ｹ0 020ｷ307 07o04o02o00006ｧ90ｷ307 09 0209 00006ｧ90ｷ30409 00000306020607 0ｸ7appleo o000607 fiapple0ｷ30ｹ0 020ｷ307 07o04o02o00006ｧ90ｷ307 02 06 020ｷ307 020306070607 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 11

13EFPIA ANNUAL MEETINGS ATHENS 2003 ﾇ 閨0702 0109 04020907 6ﾑ8.6ﾑ8. 040900 6ｧ9070006 02 06 03046ｧ8 appleo o046ｧ8 0200040407030ｷ307 0003000ｸ7030003060607: 09 09 0003006ｦ003000309 06 026ｧ907090409 020ｷ307 00apple 0909000300 02060607 0ｸ709006ｧ9 0ｹ0 09 09 0003006ｦ003000309 06 026ｧ907090409 040300070607 09 09 0003006ｦ003000309 06 026ｧ907090409 09 030607, 0ｸ7apple09030004060607 02 06 020008 03 6ｧ90ｷ307, 0903 6ｧ8 08 030007020ｷ307, 02000407o03o096ｧ9 0ｹ0, 00apple0007 6ｦ004000ｷ307 ﾇ 06006ｦ0030ｸ7070409 02090ｹ0 6ﾑ8.6ﾑ8. 03 閨020006 02o060707 ｨB09026ｧ800 02 02 oappleo6ｧ9 apple03 鐶pple0006 07 0702060000020ｷ3apple060403o6ｦ007 0000 02o0607 閨0ｹ0 appleo0306020602 閨0ｹ0 fiapple0ｷ30ｹ0 o 閨03000904o0ｹ0 020ｷ307 03o06000ｷ3 0607 02 06 000002 06 fi0000070ｷ307 07o04090007020ｷ307, 09 apple03fi03096 709 020ｷ307 020ｸ704090007020ｷ307, 02 6 70ｸ704060207 07o046ｧ800 02, 02 07 03020ｷ302060207, o 閨03000904o0ｹ0 020ｷ307 0203o086ｧ9000ｷ307, 02o apple0003066 5070303o07 02 06 02fi0009 09 6 50003026ｧ90ｷ30409 02090ｹ0 apple03fi046 5 04090ｹ0 02 06 02090ｹ0 appleo06fi020902 0ｹ0 020ｷ307 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0. O06 02o0607 閨0ｹ0 apple03o02036ｧ80400060ｹ0 appleo0ｸ7 0702060000020ｷ3apple6ｧ9ｨBo0ｸ707 o06 040603000ｹ0 02090ｹ0 06006ｦ0030ｸ70704090ｹ0 006ｧ907 06 appleo0303 閨0ｹ0 030307 o06 020ｸ70306fi020003000ｹ0 040ｸ707o6 76ｧ9ｨBo0702 06: 09 04020907 0707090209 06000307o6ｦ00ｹ0, 06 0203 0206026ｧ80ｹ0 02 06 06 040ｸ707o0306 026ｧ80ｹ0 040ｸ707000309 046ｧ9 0ｹ0 09 040209 06 04080703060409 02090ｹ0 0604fi020902 0ｹ0, 02090ｹ0 apple03fi046 5 04090ｹ0 02 06 02090ｹ0 appleo06fi020902 0ｹ0 02090ｹ0 0ｸ709006ｧ9 0ｹ0 09 04020907 0007 0300fi07060409 02090ｹ0 07o00o0300046ｧ9 0ｹ0 02 06 020907 0707apple020ｸ70109 020ｷ307 0602 060ｷ30007020ｷ307 020ｷ307 appleo0306020607 09 04020907 0008 0300o096ｧ8 030ｸ703006ｧ904000ｷ307 0906 02 08070300 02 02 06 020907 apple03o04 0300o096ｧ8 0402060ｹ0 07 閨000ｹ0 02000407o03o096ｧ9000ｹ0 09 04020907 6ｦ001090409 020ｷ307 applefi030ｷ307 0906 020907 0ｸ709006ｧ9 02 06 020907 0707apple020ｸ70109 02090ｹ0 appleo03060206026ｧ80ｹ0 6ﾒ2 02o060707 o08 閨0309 02 oappleo6ｧ9 00appleo03006ｧ9 07 apple03o026ｦ06 7o0ｸ707 applefi 020907 閨0702 0109 02 06 020ｸ7036ｧ90ｷ30ｹ0 applefi 020907 apple03o04apple07030006 0ｸ7020607 020ｷ307 040ｷ3030607 0906 0007 0300fi07060409 02 06 046ｦ0090203060409 006ｧ907 06: 09 09 0003006ｦ003000309 06 026ｧ907090409 040300070607 02 06 00apple 0909000300 02060607 0ｸ709006ｧ9 0ｹ0 09 09 6 50003026ｧ90ｷ30409 02090ｹ0 appleo06fi020902 0ｹ0 0ｸ7apple09030004060607 02 06 0ｸ7appleo o000607 09 09 6 50003026ｧ90ｷ30409 02o0ｸ7 00apple06apple 陦o0ｸ7 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 apple03fi046 5 04090ｹ0 09 09 6 50003026ｧ90ｷ30409 020ｷ307 applefi030ｷ307 0ｸ709006ｧ9 0ｹ0 09 09 0007 0ｸ70707000ｷ30409 02090ｹ0 0900fi0406 0ｹ0 0ｸ709006ｧ9 0ｹ0 09 09 060003076ｧ80ｹ0 040ｸ707000309 046ｧ9 O06 apple03o02036ｧ80400060ｹ0 02 06 02 apple03o04 o0206000007 o08 閨0309 00appleo03006ｧ9 07 apple03o026ｦ06 7o0ｸ707 applefi 0209 060003076ｧ8 040ｸ707000309 046ｧ9 02 06 020907 00apple6ｧ9 03 0409 0402 020306026ｧ80306 02 06 02o07 0203fiappleo 036ｧ86 7090ｹ0 appleo080704000ｷ307. 12 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13H 000706 6ｧ9 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 ﾞ09080307 H 000706 6ｧ9 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 ﾞ09080307 0400 0404 閨0409 0000 02060ｹ0 02060ｹ0 apple 030804 閨0ｹ0 0ｸ709006ｧ9 0ｹ00ｸ709006ｧ9 02 06 020907 020806070ｷ30706026ｧ8 04080703060409 020907 020806070ｷ30706026ｧ8 04080703060409 ﾞapplefi04apple 0400 applefi 020907 080006036ｧ9 02090ｹ0 02 0ｹ0 090707 0ｹ0 0406 00 070208apple086ｦ003080ｸ7* 6ﾑ8apple060203fiapple080ｸ7 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6ﾑ8apple06020308apple6ｧ80ｹ0 0906 020907 ﾞapple 0404fi03090409 02 06 02060ｹ0 020806070ｷ3070602 閨0ｹ0 0ｸ7apple0803 閨0400060ｹ0 6ﾑ86ｧ907 06 04 0307 00o0ｸ7 07 0209036ｦ0010ｷ3 046ｧ8000003 00 ｨB6ｧ9 04 0ｹ0 020907 閨07 030109 020ｷ307 000309 04060607 0ｸ702o6ｦ0 02o0ｸ7 040ｸ700appleo046ｧ9o0ｸ7 0000 03 閨00 020907 6ﾑ80ｸ70306apple09 02090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 02060ｹ0 07 閨000ｹ0 0003000ｸ70300036ｧ9000ｹ0 appleo0ｸ7 apple03o0408 閨030006 0402o0ｸ70ｹ0 040300-07006ｧ90ｹ0.6ｾ46ｧ8000003 006ｧ907 06 0707090209 07 01000206076ｧ8040006 0ｸ7026ｧ8 09 040ｸ7ｨB6ｧ802090409. 縺06 026ｧ9 0400 0006 00070ｷ300 閨0709 6ﾑ80ｸ70306apple09, 02 040ｸ704026ｧ800 02 0ｸ709006ｧ9 0ｹ0 0007 appleo020003o6ｦ007 appleo00o070ｷ300 閨07000ｹ0 0709046ｧ9 000ｹ0, apple03 鐶pple0006 07 040ｸ7006 5 6ｧ9ｨBo0ｸ707. ﾇ 000ｸ7030ｷ3apple 0ｸ8026ｧ8 o03o02036ｧ8030ｷ30409 02 03o036ｧ9ｨB0006 0007 00 閨030006 020907 0001 閨0306016ｧ8 02o0ｸ70ｹ0, 02fi0009 02 06 07 0ｸ702fi 00appleo03006ｧ9 07 0002apple036ｧ804040006 6ｧ8 02 06 07 0ｸ704-03000402006ｧ9 fi04o0ｸ70ｹ0 apple060402006ｦ0o0ｸ707 fi0206 02 000307060207 040ｸ704026ｧ800 02 02o06070ｷ30706026ｧ80ｹ0 apple03o0402 046ｧ9 0ｹ0 00appleo03o6ｦ007 02fi0009 07 ｨBo0ｸ707 04 07 07 apple000306o036ｧ9ｨbo0702 07 0402 000307060207 02o0ｸ70ｹ0 046ｦ007o03. ﾇ 06006ｦ0030ｸ7070409 0903 鐶pple0006 07 01000206076ｧ8040006 0ｸ7026ｧ8 09 040ｸ7ｨB6ｧ802090409 0906 026ｧ9 09 06006ｦ0030ｸ7070409 6ｧ8030300, 02 06 09 appleo06020603o00o03086ｧ9 04020907 03070ｷ30409 03 096ｧ9070006 02fi0009 000009 036ｦ002000309 0000 020907 閨0702 0109 040ｷ3030607 0402060ｹ0 oappleo6ｧ9000ｹ0 o06 00apple06 fi0400060ｹ0, 030307 02 06 02o appleo04o0402fi 02o0ｸ7 ﾞ6ﾑ809 appleo0ｸ7 06 026ｧ9030002 06 0906 020907 0ｸ709006ｧ9, apple 03 00 閨07o0ｸ707 0400 0900070602 閨0ｹ0 0903 0000 閨0ｹ0 04 000903fi020003000ｹ0 applefi 0002006ｧ907000ｹ0 appleo0ｸ7 09070ｷ3036ｧ9ｨBo0ｸ70000 04020907 03070ｷ30409 020ｷ307 0002 apple 閨070200. 0900 閨07 apple03o04 fi020600o ｨB0ｷ36ｧ80ｹ0 00060203fi020003o 02 0207 6 0403fi0706 applefi 02o 00 閨04o fi03o 02090ｹ0 03070ｷ304090ｹ0 0906 02o0ｸ70ｹ0 0707 03000ｹ0, 02 06 4 0403fi0706 apple00036ｧ9appleo0ｸ7 0906 02060ｹ0 090ｸ7-07 6ｧ902000ｹ0, 02 02 03 6 5 6ｧ907o0ｸ70000 apple06o 006ｧ907 06 02o 00 閨090003o0ｹ0 02090ｹ0 apple03ofi o0ｸ7 appleo0ｸ7 apple03 鐶pple0006 07 04090000060ｷ303006ｧ9, 02 06 09 oappleo6ｧ9 0007 08o0307 00fi07o 02o 046ｦ004020900 0ｸ709006ｧ9 0ｹ0, 030307 02 06 020907 02o06070ｷ3076ｧ9 090007060207. ﾇ 0ｸ709006ｧ9, 0ｷ30402fi04o, appleo020003006ｧ9 02o apple030602o 040ｸ70402 020602fi 0402o0604006ｧ9o 02o0ｸ7 00 07030306apple0607o0ｸ7 020008 03 6ｧ9o0ｸ703, 02 06 0ｸ702fi 0000 0209 0400060307 02o0ｸ7 02o07 apple030ｷ302 03040602fi apple 030709o0702 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02 06 02090ｹ0 o0602o07o0006026ｧ80ｹ0 0707apple020ｸ701090ｹ0. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 13

13EFPIA ANNUAL MEETINGS ATHENS 2003 O06 02o0607 閨0ｹ0 apple03o02036ｧ80400060ｹ0 O 6 5 040602fi0ｹ0 03fi09o0ｹ0 fi000ｷ30ｹ0 0906 02o07 oappleo6ｧ9o apple03 鐶pple0006 07 01000206076ｧ8040006 09 040ｸ7ｨB6ｧ802090409 0ｸ7026ｧ8 006ｧ907 06 o06 02o0607 閨0ｹ0 apple03o02036ｧ80400060ｹ0. 0003o06 09070ｷ3036ｧ9ｨBo0ｸ70000 fi0206 o06 apple03o02036ｧ80400060ｹ0 0ｸ702 閨0ｹ0 006ｧ907 06 09 040807030006 02090ｹ0 0ｸ709006ｧ9 0ｹ0, 09 02 036ｦ002000309 00070900 閨030ｷ3-0409 020ｷ307 040300070607, o06 0303 09 閨0ｹ0 02090ｹ0 02o06070ｷ3076ｧ9 0ｹ0, 09 02000407o03o0906026ｧ8 apple03fio o0ｹ0. ﾇ 040900 07020602fi02000309 apple ｯ fi03000ｹ0 006ｧ907 06 07 00086ｧ96 5o03 09 0900o0903 0806026ｧ8 096ｧ803 070409, appleo02 閨03000400 02090ｹ0 oappleo6ｧ9 0ｹ0 03 006ｧ907 06 09 6ｦ001090409 02o0ｸ7 appleo04o0402o6ｦ0 020ｷ307 02fi000ｷ307 07070ｷ3 020ｷ307 65 00020607, 02 0207 020907 00applefi00000709 2500026ｧ9, applefi 16% 0400 22% 02o0ｸ7 040ｸ707o030602o6ｦ0 apple0309030ｸ70400o6ｦ0. 05000206026ｧ8 040ｸ707 鐶pple0006 02090ｹ0 02 036ｦ0020003090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 appleo020003000400 020602fi020902 0ｹ0 020ｷ307 040ｸ70402090007020ｷ307 apple00036ｧ903 036 7090ｹ0. 030402fi04o, o06 apple0707000ｹ0 0906 020907 0ｸ709006ｧ9 0ｸ7010707o0702 06 appleo036ｦ0 00000207 020907 090306026ｧ9 020ｷ307 65 00020607 02 06 02fi0009 apple0003060404fi020003o 00000207 020907 090306026ｧ9 020ｷ307 80 00020607. O06 0006 0602o6ｧ9, 0209 0907060009 020ｷ307 oappleo6ｧ90ｷ307 ｨB6ｧ802090400 09 6ﾑ8apple060203oapple6ｧ8, 0002020600o6ｦ007 fi0206 o06 0900fi0406000ｹ0 apple0707000ｹ0 0906 020907 0ｸ709006ｧ9 03 0ｸ7010903o6ｦ007 02 0207 1 閨0ｷ30ｹ0 1,5 appleo04o040206 6ｧ9000ｹ0 00o0707 000ｹ0 02o0ｸ7 ﾞ6ﾑ809 閨0ｷ30ｹ0 02o 2050 03fi090ｷ3 02090ｹ0 096ｧ803 0704090ｹ0. 6ﾑ80202fi0ｹ0 applefi 020907 6ｦ001090409 0ｸ7026ｧ8 apple03 鐶pple0006 07 040ｸ70700020206000903o6ｦ007 02 06 o06 070303000ｹ0 040ｸ707 鐶pple0006000ｹ0 02090ｹ0 096ｧ803 0704090ｹ0, 0402060ｹ0 040ｸ70702070100060ｹ0, 0906 apple 0307 00060900. ﾇ 6ﾑ80ｸ70306apple09 00appleo00 閨070ｷ30ｹ0 apple03 鐶pple0006 07 040ｸ70700046ｧ9040006 02060ｹ0 apple03o04apple07030006 閨0ｹ0 02090ｹ0 06040200 o06 00000303o07020602 閨0ｹ0 09000706 閨0ｹ0 020ｷ307 09030602060ｷ300 閨070ｷ307 07 00appleo03 閨04o0ｸ707 07 ｨB6ｧ804o0ｸ707 apple0003060404fi020003o, 0000 02 036ｦ002000309 0ｸ709006ｧ9. ﾞ0ｸ702fi 03 006ｧ907 06 02 02 ｯ 0304070ｹ0 02o appleo02 閨03000400 020ｷ307 appleo03060206020607 apple03fi03096 7090ｹ0 02 06 090ｷ3096ｧ80ｹ0 0ｸ709006ｧ9 0ｹ0, appleo0ｸ7 6 5036ｧ90402o0702 06 0402o 00apple6ｧ90200070203o 02090ｹ0 02o0607o0206026ｧ80ｹ0 040203 02090906026ｧ80ｹ0 0ｸ709006ｧ9 0ｹ0 0906 02o 2000-2006. ﾞ0ｸ702fi 03 006ｧ907 06 00apple6ｧ904090ｹ0 02 06 02o appleo02 閨03000400 02090ｹ0 閨03000ｸ707 0ｹ0 02 06 02090ｹ0 02 0607o02o006ｧ9 0ｹ0 02090ｹ0 6 506o000904 076ｧ9 0ｹ0 04 0ｹ0, 06 6ｧ90ｷ30ｹ0 0402o07 appleo030307 0ｸ7appleo0404fi- 000007o 02o00 陦 020ｷ307 0403000700060607 appleo0ｸ7 040ｸ707 鑰0702 06 0000 0209 000009070309 090306026ｧ9. O03o02036ｧ8030ｷ30409, 06006ｦ0030ｸ7070409, 02o0607 閨0ｹ0 apple03o02036ｧ80400060ｹ0, 0100020607060702 0ｹ0 applefi 0ｸ7026ｧ8 02090ｹ0 096ｧ803 0704090ｹ0: 6ｧ8030300 09 0603 07 020707o0ｸ70000 02fi0009 020907 000ｸ7030ｷ3apple 0ｸ8026ｧ8 040ｸ707000309 046ｧ9 apple06o 040200076ｧ8 04020907 0ｸ7apple090300046ｧ9 02o0ｸ7 02o0607o6ｦ0 o0307-00 02o0ｹ0 0906 020907 0ｸ709006ｧ9. 0906 040ｸ707000309 046ｧ9 appleo0ｸ7 apple03 鐶pple0006 07 07 09070ｷ3036ｧ9040006 02o07 06 06 6ｧ9020003o 04 03 02026ｧ803 02o0ｸ7 000400o6ｦ0 020ｷ307 040ｸ700appleo0306020607 00 0ｹ0 0000 02o 046ｦ004020900 0ｸ709006ｧ9 0ｹ0 02o0ｸ70ｹ0. O 000400fi0ｹ0 0ｸ702fi0ｹ0 006ｧ907 06 06 06 6ｧ9020003o0ｹ0 0906 026ｧ9 o06 040ｸ700appleo036ｧ902000ｹ0 00 0ｹ0 09070ｷ3036ｧ9ｨBo0ｸ707 fi0206 09 6ﾑ80ｸ70306apple09 006ｧ907 06 09 apple000306o046ｧ8 02o0ｸ7 02fi0400o0ｸ7 appleo0ｸ7 apple 03 閨040006 020907 02 036ｦ002000309 apple00036ｧ903 036 709. 6ﾑ86ｧ907 06 0002006ｧ90709 0000 02o 000009 036ｦ0020003o apple03o04 fi020600o ｨB0ｷ36ｧ80ｹ0, 02o oappleo6ｧ9o 0ｸ7016ｧ803090200 02 0207 5 閨0209 040209 060703020006 02090ｹ0 020003000ｸ702 6ｧ9 0ｹ0 020306 02o0702 00026ｧ9 0ｹ0. ﾒ 0207 020907 6ｧ9 06 0403o0706026ｧ8 apple00036ｧ9o o 09 apple 06 06026ｧ8 030709040600fi020902 0000060603090200 040900 0702060207, apple000307060702 0ｹ0 0400 appleo04o0402fi 00060203fi020003o 02o0ｸ7 5 ｨｰ 000706 0100apple000307o6ｦ00400 02o 23 ｨｰ. 0307 0000090703o 00 閨03o0ｹ0 020ｷ307 00apple06020ｸ704060607 0ｸ7020607 00appleo03006ｧ9 07 appleo o03006ｧ9 0402 040ｸ704026ｧ800 02 0ｸ709006ｧ9 0ｹ0, 0906 026ｧ9 o08006ｧ9030002 06 04020907 apple03fi03096 709, 04020907 00010ｷ307o04o02o000006 026ｧ8 02 06 040209 07o04o02o000006 026ｧ8 apple00036ｧ903 036 709, 02 03060ｹ0 02 06 040209 04030900 02o fi0209046ｧ8 02o0ｸ70ｹ0 appleo0ｸ7 040209036ｧ9ｨB0002 06 04020907 000ｸ703006ｧ9 0207030ｸ76 709 02o0ｸ7 apple0309030ｸ70400o6ｦ0. ﾞappleo020003o6ｦ007 00appleo00 閨070ｷ30ｹ0 040ｸ70402 020602fi 0402o0604006ｧ9o 020ｷ307 06 030ｸ70206020607 03040607 02o0ｸ7 02o06070ｷ3070602o6ｦ0 00 0ｹ0 00o0702 閨03o0ｸ7. 6ｾ402o0604006ｧ9o 02o oappleo6ｧ9o 閨040006 07 09070ｷ303060402006ｧ9 applefi 02o 0407030209 020ｷ307 0300000003060ｷ3 0607 0602 060ｷ30007020ｷ307 appleo0ｸ7 000902036ｧ90309-0200 02o 040002 閨006 50306o 02o0ｸ7 2000, fiappleo0ｸ7 06 0209036ｦ004040002 06 fi0206 fi03o06, 0700010703020902 applefi 02o 00apple6ｧ9apple00 o 000604o 6ｧ8-00 02o0ｹ0, 閨04o0ｸ707 0602 6ｧ90ｷ300 apple03fi046 5 04090ｹ0 0400 appleo06o020602 閨0ｹ0 0ｸ7apple090300046ｧ9000ｹ0 apple03fi03096 7090ｹ0 02 06 apple00036ｧ903 036 7090ｹ0. 03040006 07 09070ｷ303060402006ｧ9 00apple6ｧ904090ｹ0 applefi 0209 6ｾ40ｸ707036ｧ80209, 09 oappleo6ｧ9 07 09070ｷ3036ｧ9ｨB0006 020907 apple030ｷ302 030406026ｧ8 0300o 06fi020902 020ｷ307 0203 020607 0000030607 fi04o07 08o0307 020907 o030907070ｷ30409 02 06 0209 04030900 02o fi02090409 020ｷ307 040ｸ70402090007020ｷ307 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 02o06070ｷ30706026ｧ80ｹ0 apple03o0402 046ｧ9 0ｹ0. O06 040ｸ700appleo036ｧ902000ｹ0 00 0ｹ0, 00 閨040ｷ3 020ｷ307 0002apple03o0406apple0ｷ307 02o0ｸ70ｹ0 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ｾ40ｸ707 閨03000ｸ70409, 0002080307ｨBo0ｸ707 0209 04 086ｧ8 00apple06030ｸ7006ｧ9 02o0ｸ70ｹ0 07 06 0209030903006ｧ9 0ｸ7026ｧ8 09 0ｸ7apple0003o046ｧ8 02090ｹ0 03046ｧ80ｹ0 02090ｹ0 00apple0602o0ｸ7030602fi020902 0ｹ0 0402o 00000303o07020602fi 046ｦ00702 0900. 00apple0ｷ30ｹ0 fi000ｷ30ｹ0 00apple06030ｸ700o6ｦ007 02 06 020907 0707apple020ｸ70109 0006 apple03 0900 0206026ｧ80ｹ0 6ﾑ80ｸ70306apple090ｹ0 02090ｹ0 0ｸ709006ｧ9 0ｹ0. ﾞ07020600 閨020ｷ3apple09 0000 02060ｹ0 apple03o02036ｧ80400060ｹ0 0ｸ702 閨0ｹ0, 0000 02 06026ｧ800 02 0ｸ70207, appleo0ｸ7 appleo0303 閨0ｹ0 08o03 閨0ｹ0 006ｧ907 06 07020608 0206-0207, 09 03070ｷ30409 apple03o040ｷ303006ｧ9 0000 046ｦ007000409 030307 02 06 080603o o016ｧ9. 09o03006ｦ00002 06 0000 6 5070409 6ｦ0o 0701o07000ｹ0: 02o07 0002040ｸ7090403o07060400fi 02o0ｸ7 0602 6ｧ9o0ｸ7, 0000 0402oapplefi 020907 apple0003 0602 閨030ｷ3 apple03o0603090409 02090ｹ0 0003006ｦ0030003090ｹ0 020ｸ70203o08o036ｧ9 0ｹ0 020ｷ307 02fi000ｷ307, 02 06 020907 0707apple020ｸ70109 0007fi0ｹ0 000ｸ7030ｷ3apple 0ｸ802o6ｦ0 040ｸ70702o07060400o6ｦ0 020ｷ307 appleo03060206020607 0906 020907 02o06070ｷ3-0706026ｧ8 apple03o0402 046ｧ9, 06040200 o06 apple03o02036ｧ80400060ｹ0 07 0702060000020ｷ3apple060402o6ｦ007 applefi 02o0607o6ｦ0 閨04o0702 0ｹ0 0ｷ30ｹ0 6 5070409 020907 0000apple0006036ｧ9 02 06 02060ｹ0 6 5 閨0302060402000ｹ0 apple03 02020602 閨0ｹ0 02o0ｸ7 02 030007fi0ｹ0. 14 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

1308090006o07o0006026ｧ8 apple00036ｧ903 036 709 02 06 0003006ｦ003000309 020ｸ70203o08o036ｧ9 : 09 07o00o03o096ｧ9 ﾇ 07o00o03o096ｧ9 02o0ｸ7 040602 040209036ｧ9o0ｸ7, applefi 02o 1998, 02o076ｧ9ｨB0006 0006 apple03 0900 020602fi020902 : 04 ｯ 閨07 07 0007oappleo060900 閨07o 040603o fiapple0ｷ30ｹ0 006ｧ907 06 09 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409, fiappleo0ｸ7 0ｸ7apple070304o0ｸ707 o06 03000000030606 00060ｹ0 0003000ｸ70300036ｧ9000ｹ0 020ｸ70203o08o036ｧ9 0ｹ0ｨC 02fi000ｷ307, 0ｸ7apple09030004060607, apple03o0ｸ8fi- 07020ｷ307, 02 0203070209 o08006ｧ903o0ｸ707 07 04 閨6 5o0702 06 02o 02o0607o020602fi 6ｧ9-02 06o, 06 6ｧ90ｷ30ｹ0 02060ｹ0 0304 閨0ｹ0 02o0ｸ7 0702 090ｷ307060400o6ｦ0 02 06 02090ｹ0 0003006ｦ00300-03090ｹ0 020ｸ70203o08o036ｧ9 0ｹ0, 02 0207 020907 070402090409 020ｷ307 0300o 06o026ｧ8020ｷ307 02o0ｸ70ｹ0 0402o07 02o00 陦 02090ｹ0 0ｸ709006ｧ9 0ｹ0, 02 06 0900070602fi020003 02090ｹ0 02o06070ｷ30706-026ｧ80ｹ0 apple03o0402 046ｧ9 0ｹ0. ﾒ 06 0203066 5060ｹ0 00apple0006 6ｧ8 09 o03o02036ｧ8030ｷ30409 apple03o040ｷ303006ｧ9 026ｧ903000702 06 02 ｨB09026ｧ800 02 02 oappleo6ｧ9 02 03o6ｦ00702 06 07 036ｦ004o0ｸ707 o06 0602 0402 閨0ｹ0, 02 06 fi0406 07026ｧ9040203o08. 030402fi04o o06 0003000ｸ70300036ｧ9000ｹ0 0ｸ702 閨0ｹ0 0007 006ｧ907 06 applefi030ｸ702000ｹ0. 6ﾑ86ｧ907 06 0ｸ707 02fi07 07 apple000306o03060402o6ｦ007 000707 apple000603006ｧ902 06 09 0602 07fi020902 020ｷ307 0203 020607 07 o0309 070604o0ｸ707 閨07 appleo06o020602fi 046ｦ004020900 apple00036ｧ903 03-6 7090ｹ0 0000 apple03fi046 5 0409 0906 fi03o0ｸ70ｹ0 6ｧ8 09 o0602o07o0006026ｧ8 0604o0303oapple6ｧ9 020ｷ307 040ｸ70402090007020ｷ307. O apple030ｷ302 03040602fi0ｹ0 03fi09o0ｹ0 6ｦ0apple 0301090ｹ0 0007fi0ｹ0 040ｸ704026ｧ800 02o0ｹ0 apple00036ｧ903 036 7090ｹ0 006ｧ907 06, 0203066 5060ｹ0, 07 apple03o0408 閨030006 ﾇ 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 ﾒ070302 ﾞ040807030604090ｹ0 0809006ｧ9 0ｹ0 0402o07 apple0309030ｸ70400fi appleo06o0206026ｧ8 apple00036ｧ903 036 709 04020907 oappleo6ｧ9 03 閨04o0ｸ707 apple03fi046 5 0409 fi03o06 02 06 09 oappleo6ｧ9 03 006ｧ907 06 o0602o07o00060207 6 5060604060009. ﾞ0ｸ702fi 040900 6ｧ9070006 fi0206 o06 0ｸ7apple006ｦ0030ｸ707o06 0906 02o 046ｦ004020900 apple03 鐶pple0006 07 06 03 閨02o0ｸ707 020907 0602 07fi020902 07 apple03o0903 0000 026ｧ9ｨBo0ｸ707 020907 apple 03o046ｧ8 0ｸ7apple09030004060607 apple00036ｧ903 036 7090ｹ0, 006ｧ90200 apple03fi02000602 06 0906 020907 06 020306026ｧ8 0900o0903 086ｧ9 006ｧ90200 0906 02 0203006 5070206 0402 07o04o02o00006ｧ9 006ｧ90200 0906 02o07 0001oapple03060400fi. ﾇ 020ｸ70203o08o036ｧ9 020ｷ307 040300070607 0906 03fi09o0ｸ70ｹ0 apple00036ｧ903 036 7090ｹ0 0400 閨07 070303o 02030702o0ｹ0 00 閨03o0ｹ0 0007 00appleo03006ｧ9 07 006ｧ907 06 0003006ｦ003000309 02 06 040ｷ3036ｧ90ｹ0 apple000306o0306-0400o6ｦ00ｹ0, 00apple0006 6ｧ8 apple03 鐶pple0006 07 06 0209030903006ｧ9 09 0602 07fi020902 o030907070ｷ3-04090ｹ0 02 06 apple03o0903 0000 02060400o6ｦ0 020ｷ307 0ｸ7apple09030004060607 apple00036ｧ903 036 7090ｹ0 0402060ｹ0 040603000ｹ0 0ｸ7appleo o046ｧ80ｹ0 020ｷ307 040300070607. 縺06 ｯ 0ｸ702fi07 0203066 5060ｹ0 02o 03fi09o 006ｧ907 06 07 0902 6ｧ9o o06 0206076ｧ80400060ｹ0 020ｷ307 040300070607 07 06 鐶ppleo0702 06 applefi 06000003006ｧ90ｹ0 040ｸ7006 5070400060ｹ0, 08o6ｦ0 09 0300o 06fi020902 0906 020907 o030907070ｷ30409 02090ｹ0 apple00036ｧ903 036 7090ｹ0 076ｧ8020006 0402 6ｧ9 06 02 0203070209 00 閨0309, fiapple0ｷ30ｹ0 0ｸ7026ｧ8 appleo0ｸ7 0ｸ7apple000903070809 apple03fi0408 02 000002 016ｦ0 ﾇ070ｷ300 閨07o0ｸ7 08 040603006ｧ9o0ｸ7 02 06 080003096ｧ9o0ｸ7. 01030006 ｨBfi02 07 閨07 0404 陦06o-o03fi040900o 0906 07 090006o0ｸ703090903006ｧ9 0006 0ｸ707 0006026ｧ8 0ｸ7apple 閨03 0006 0ｹ0 6ﾑ80ｸ70306apple090ｹ0 02090ｹ0 0ｸ709006ｧ9 0ｹ0 0906 02o0ｸ70ｹ0 6ﾑ80ｸ7030ｷ3apple 6ｧ9o0ｸ70ｹ0 appleo0ｸ7 020607o6ｦ00702 06 0906 03fi09o0ｸ70ｹ0 00apple 0909000300 020602o6ｦ00ｹ0, 04appleo0ｸ7 0607 6ｧ8 07 6 70ｸ7046ｧ80ｹ0. 縺06 02o 03fi09o 0ｸ702fi apple03fi02000607 0402o 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi 6ｾ40ｸ7006 5o6ｦ00306o 0209 090006o0ｸ703096ｧ9, apple030607 applefi 02o 02 閨03o0ｹ0 02o0ｸ7 2004, 0006 0ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02070302 0ｹ0 040807030604090ｹ0 0ｸ709006ｧ9 0ｹ0 09 oappleo6ｧ9 03 07020602 02 04026ｧ8040006 fi03 02 閨07020ｸ7apple appleo0ｸ7 040309040600oappleo06o6ｦ00702 06 046ｧ8000003 02 0207 0209 060703020006 0006 0ｹ0 046ｦ00702o00090ｹ0 apple 03 00o076ｧ80ｹ0. ﾒ 06 0000 020907 000ｸ702 06036ｧ9 07 0002040ｸ7090403o076ｧ904o0ｸ70000 02o07 02 07o07060400fi 0402o07 oappleo6ｧ9o 6 5 046ｧ9ｨB0002 06 o 000ｸ7030ｷ3apple 0ｸ802fi0ｹ0 040ｸ70702o07060400fi0ｹ0, 000ｸ7030ｸ70903 00006ｧ9ｨBo0702 0ｹ0 apple03o0ｹ0 02 00apple07070ｷ3 02 0602 060600 02 0906 020907 0ｸ7090006o07o0006026ｧ8 apple00036ｧ903 036 709 02 06 apple03oappleo06060702 0ｹ0 02060ｹ0 06 0602 046ｧ9000ｹ0. O 0200030602fi0ｹ0 0402fi04o0ｹ0 006ｧ907 06 09 090006o0ｸ703096ｧ9 0006 0ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 00 閨010ｸ7apple07090ｹ0 02070302 0ｹ003, 07 02 06 0003apple6ｧ9ｨB0ｷ3 fi0206, 04070309 0402o 0404 陦06o NetC@rds, 040209 060703020006 020ｷ307 O030ｸ700apple06 020607 ﾞ0906070ｷ307 appleo0ｸ7 03 096ｧ907o0ｸ707 04020907 ﾞ036ｧ807 02o0ｸ7 0403fi07o0ｸ7, 03 o6ｦ00000 07 apple 03 閨040002 06 0400 09000300 07o6ｦ00ｹ0, 0ｸ704020306 02o6ｦ00ｹ0, 09070303o0ｸ70ｹ0, 6ｧ9040ｷ30ｹ0 02 06 6 5 閨0309o0ｸ70ｹ0 02 06 0602 03o6ｦ00ｹ0 00apple060402 鐶pple02000ｹ0, 06 020306026ｧ8 apple00036ｧ903 036 709 00 06 04020907 6ﾑ8030307 04070309 04020907 00030706026ｧ8 02o0ｸ70ｹ0 02070302 040807030604090ｹ0 0ｸ709006ｧ9 0ｹ0 09 oappleo6ｧ9 03 096ｧ9070006 00000ｸ7030ｷ3apple 0ｸ8026ｧ8 02070302 03. 03020406, 09 6ﾑ80ｸ70306apple09 02090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 09 6ﾑ80ｸ70306apple09 020ｷ307 appleo0306020607 03 apple0909 6ｧ907o0ｸ707 04 閨0306 04 閨0306, 0000 0ｸ702fi 02o 006ｦ0020003o 00apple6ｧ902000ｸ70900, 036ｧ909o 02 0603fi 00000207 020907 000604 090ｷ3096ｧ8 02o0ｸ7 000ｸ70306. 09fi07o 09 02060709020602fi020902 fi000ｷ30ｹ0 0007 appleo020003006ｧ9 apple070702090409 0402060ｹ0 02o0607 閨0ｹ0 apple03o02036ｧ80400060ｹ0 appleo0ｸ7 0702060000020ｷ3apple6ｧ9ｨBo0ｸ707 02 040ｸ704026ｧ800 02 0ｸ709006ｧ9 0ｹ0. 0903o02036ｧ80400060ｹ0 0402060ｹ0 oappleo6ｧ9000ｹ0 0001070303o0ｸ7 apple030ｷ302 090ｷ307060402006ｧ90200, 06 6ｧ90ｷ30ｹ0 00 閨040ｷ3 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 07o00o0300046ｧ9 0ｹ0 02 06 020ｷ307 06 0602 04060607 0906 0209 060703000409 020ｷ307 apple03o0ｸ8fi07020ｷ307 04020907 09o0307, appleo0ｸ7 020707o0ｸ707 02 000ｸ7030ｷ3apple 0ｸ80207 apple03fi020ｸ7apple 02 apple 060209020602fi020003 0402o07 02fi0400o. 09060402006ｦ00ｷ3 apple0ｷ30ｹ0 046ｧ8000003 apple03 鐶pple0006 07 020707o0ｸ70000 02o 6 56ｧ800 02 06 07 040ｸ700080ｷ3076ｧ804o0ｸ70000 04040002060207 0000 02o07 000ｸ7030ｷ3apple 0ｸ802fi 040ｸ70702o07060400fi 0906 07 0702060000020ｷ3apple6ｧ904o0ｸ70000 02060ｹ0 06 0302060ｹ0 0ｸ701 07fi000007000ｹ0 apple03o02036ｧ80400060ｹ0. O 000ｸ7030ｷ3apple 0ｸ802fi0ｹ0 040ｸ70702o07060400fi0ｹ0 020ｷ307 appleo03060206020607 0906 020907 02o06070ｷ30706026ｧ8 apple03o0402 046ｧ9 090703060402, 02 040ｸ704026ｧ800 02 0ｸ709006ｧ9 0ｹ0 020ｷ307 040ｷ3030607 00 0ｹ0 0007 03 00appleo03 閨04o0ｸ707 07 0702 appleo02030603o6ｦ007 0402060ｹ0 apple03o02036ｧ80400060ｹ0 0ｸ702 閨0ｹ0 apple 0307 00fi07o 000707 fi03o06 o06 040ｸ707020003000402 閨0ｹ0 02o0ｸ7 040ｸ704026ｧ800 02o0ｹ0 00070604o0ｸ707 02060ｹ0 0ｸ707070000060ｹ0 02o0ｸ70ｹ0 0400 040ｸ700apple03070100060ｹ0 000002 03036ｦ003000604090ｹ0. 0903 鐶pple0006 07 02 02 6 5030903o6ｦ007 apple03o04apple07030006000ｹ0 040ｸ7006 5066 5 0400o6ｦ0 020ｷ307 040ｸ700080003fi07020ｷ307 020ｷ307 0900fi04060ｷ307 03040607, 020ｷ307 00apple 0909000300 02060607, 020ｷ307 000309 040209036ｧ90ｷ307, 020ｷ307 0900fi04060ｷ307 06 030ｸ70007020ｷ307 0ｸ7090006o07o0006026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0, 020ｷ307 06 030ｸ70007020ｷ307 040ｸ700apple0309030ｷ300 0206026ｧ80ｹ0 040807030604090ｹ0. 010ｷ3036ｧ90ｹ0 07 01000407070000 02o0ｸ70ｹ0 04036ｧ80402000ｹ0 02 06 02o0ｸ70ｹ0 04030007006ｧ90ｹ0, appleo0ｸ7 apple 0602o6ｦ007 apple0003060404fi02000309 06 0807070006 applefi 02 040ｸ704026ｧ800 02 02 06 000009 036ｦ002000309 040ｸ700000002o046ｧ8 040209 03000602o0ｸ703096ｧ9 02o0ｸ70ｹ0. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 15

13EFPIA ANNUAL MEETINGS ATHENS 2003 O06 040ｸ700apple03070100060ｹ0 0ｸ702 閨0ｹ0 08o03o6ｦ007 0ｸ7appleo0403000ｷ302060207 fi03 02 00apple6ｧ9- apple00 00 06 020ｸ76 5 閨03070904090ｹ003, applefi 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409 閨0ｷ30ｹ0 02o0ｸ70ｹ0 02oapple0602o6ｦ00ｹ0 08o03006ｧ90ｹ0. O 02 03 閨07 0ｹ0 閨040006 閨07 03fi03o 07 06-03 00 026ｧ9040006 02 06 apple03 鐶pple0006 07 閨040006 040ｸ707006ｧ9 090409 020ｷ307 000ｸ7030ｸ7070607 02o0ｸ7. ﾇ 03070ｷ30409 00appleo03006ｧ9 閨020406 07 040ｸ7006 507030006 040209 040ｸ707000309 046ｧ9 040ｷ3030607 appleo0ｸ7 閨04o0ｸ707 apple03070900 02 07 appleo0ｸ707 02 06 07 000703o0ｸ707 09 006ｧ9 applefi 020907 07030309, 08o6ｦ0 0702060000020ｷ3apple6ｧ9ｨBo0ｸ707 070703o09000ｹ0 apple03o02036ｧ80400060ｹ0. ﾇ 040ｸ707000309 046ｧ9 0ｸ7026ｧ8, 09 oappleo6ｧ9 03 08 閨030006 0400 00apple 086ｧ8 02060ｹ0 0300fi 06000ｹ0 0906 03 閨00 02 0ｸ709006ｧ9 0ｹ0 0304 閨0ｹ0, 00appleo03006ｧ9 07 appleo020003 閨040006 閨07 02 02 030ｸ7020602fi 00 閨04o 0906 02060ｹ0 000002 03030ｸ703006ｧ90400060ｹ0 0400 0003070602fi 00apple6ｧ9apple00 o. 縺06 026ｧ9 040ｸ7040707 o06 06026ｧ9000ｹ0 020ｷ307 apple03o6 503090007-020ｷ307 6ｧ8 02090ｹ0 000002 02fiapple0604090ｹ0 020ｷ307 apple 070607 6 5036ｧ90402o0702 06 00 閨04 0402 6ｧ9 06 02 000307060207 040ｸ704026ｧ800 02 02 06 00fi07o o06 040ｸ707020003000402 閨0ｹ0 020ｷ307 040ｸ70402090007020ｷ307 0ｸ7020607 00appleo03o6ｦ007 07 0604o0ｸ707 036ｦ00400060ｹ0. 縺06 02o0ｸ70ｹ0 03fi09o0ｸ70ｹ0 0ｸ702o6ｦ00ｹ0, 09 6ﾑ8apple060203oapple6ｧ8 閨040006 apple03o02006ｧ9070006 020300060ｹ0 00 0203oapple03fi03000400o0ｸ70ｹ0 0402fi04o0ｸ70ｹ0 0906 02 040ｸ704026ｧ800 02 0ｸ7090006o07o0006-026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0, 06 6ｧ90ｷ30ｹ0 0400 0404 閨0409 0000 0209 096ｧ803 070409: 09030602o07, apple03 鐶pple0006 07 0001 0408 03060402006ｧ9 09 apple03o046 5 040600fi020902 04020907 apple00036ｧ903 036 709, 06 6ｧ90ｷ30ｹ0 0906 02o0ｸ70ｹ0 07appleo03o0ｸ70ｹ0, 0906 026ｧ9 appleo020003006ｧ9 03000000030606 000ｹ0 0602 6ｧ90ｷ300. 6ﾑ8apple066 50703030006 fi000ｷ30ｹ0 00apple6ｧ904090ｹ0 07 00000300026ｧ804o0ｸ70000 04 08006ｧ90ｹ0 02 06 appleo020003000400 020602o6ｦ00ｹ0 000904 07060400o6ｦ00ｹ0 0106o03fi090904090ｹ0 020ｷ307 07 閨0ｷ307 apple03o0ｸ8fi07020ｷ307 6ｧ8 030003 apple00060607, 0000 0402oapplefi 07 apple03o0408 閨03o0ｸ70000 apple03fi046 5 0409 04020907 06 020306026ｧ8 apple03fio o appleo0ｸ7 040ｸ707 0ｸ707ｨB0006 02 07 000007fi000007 o08 閨0309 0906 020907 0ｸ709006ｧ9 02 06 02o0ｸ70ｹ0 06 03 閨040600o0ｸ70ｹ0 applefi03o0ｸ70ｹ0. ﾞ0ｸ702fi0ｹ0 o 0909006ｧ9 0402o0ｸ70ｹ0 6ｦ0o 070303o0ｸ70ｹ0 0402fi04o0ｸ70ｹ0, 020907 appleo06fi020902 02 06 020907 o0602o07o0006026ｧ8 6 5060ｷ3040600fi020902. 040007 006ｧ907 06 00fi07o fi0206 09 6ﾑ80ｸ70306apple09 06 03 閨020006 06 08o030002060207 040ｸ704026ｧ800 02 apple00036ｧ903 036 7090ｹ0, 030307 fi0206 09070ｷ3036ｧ9ｨB0006 02 06 0006 appleo060206036ｧ9 apple03 020206020607 02 06 appleo02000300040007020ｷ307, 0906 020907 6ｧ9 06 0403 閨070006, appleo0303 閨0ｹ0 08o03 閨0ｹ0 02 06 00 閨04 04020907 6ｧ9 06 040603. ﾞapple 閨04o0ｸ70000 appleo036ｦ0 applefi 02o 07 06 03 閨02o0ｸ70000 06 02030602 閨0ｹ0 07 08o03 閨0ｹ0, 6ｧ8 apple03060ｹ0 040ｸ70902036ｧ9040600 00 o00 閨07, appleo0ｸ7 03 00apple 閨020300apple 07 07 apple03o04 06o03060402o6ｦ007 o06 06026ｧ9000ｹ0 020ｷ307 06 08o030607 0ｸ7020607 02 06 07 02030603006ｧ9 09 apple03 0900 0206026ｧ8 appleo06fi020902 020ｷ307 apple03 020206020607. 030402fi04o, 09 "0009 appleo06fi020902 " 0402 07o04o02o00006ｧ9 閨040006 000702oapple060402006ｧ9 00 06 02 06 appleo036ｦ0 02 0603fi 0ｷ30ｹ0 apple 030709o0702 0ｹ0 6ｦ0010904090ｹ0 020ｷ307 apple - 070607. 05 鐶pple0300apple00 03o06applefi07 07 096ｧ907o0ｸ707 000ｸ7030ｷ3apple 0ｸ802 閨0ｹ0 0702 0303-09 閨0ｹ0 0906 07 apple03o04 06o03060402006ｧ9 0206 006ｧ907 06 0ｸ702fi appleo0ｸ7 04 03 020209036ｧ9ｨB0006 0006 030003 apple006ｧ9 appleo06fi020902 0ｹ0, 0006 030003 apple006ｧ9 appleo0ｸ7 0ｷ3080003006ｧ9 020907 07030306apple060709 0ｸ709006ｧ9 apple 03 00 閨07o0702 0ｹ0 02 0ｸ702fi0403o07 00 閨04 0402 fi0306 02o0ｸ7 apple03o00appleo03o09060400o6ｦ0 appleo0ｸ7 02 03o036ｧ9ｨBo0702 06 applefi 020907 03-00fi 06 03046ｧ8. 05 鐶pple0300apple00 00apple6ｧ904090ｹ0 07 0402000802o6ｦ00000 020907 apple03o04 0300o096ｧ8 o03060400 閨070ｷ307 02o0607o0206020607 02 07fi070ｷ307, 02 06 00060306 06 6ｧ90ｷ30ｹ0 0906 02o0ｸ70ｹ0 02 07fi07000ｹ0 0002006ｧ907o0ｸ70ｹ0 appleo0ｸ7 02 03o036ｧ9ｨBo0ｸ707 02060ｹ0 apple 06026ｧ80400060ｹ0 0906 020907 030406026ｧ8 02 02070302060409 020ｷ307 00apple 0909000300 02060607 02090ｹ0 0ｸ709006ｧ9 0ｹ0, 030307 0007 07 08 閨03o0ｸ707 appleo0ｸ703000707 0209 040ｸ707000406ｨBfi- 00000709 06 020306026ｧ8 02 02070302060409, 0209 04020609006ｧ8 appleo0ｸ7 fi03o06 00 0ｹ0 09070ｷ3-036ｧ9ｨBo0ｸ70000 fi0206 o06 06 02030602 閨0ｹ0 0907060400060ｹ0 046ｧ8000003 0100apple00030706o6ｦ00702 06 00 閨04 0400 036ｧ909 0403fi0706. 09000207 02o 2000, 02 06 02o 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi 6ｾ40ｸ7006 5o6ｦ00306o 02090ｹ0 060404-6 50607 0ｹ0, 04090000060603090200 apple03 0900 0206026ｧ8 apple03fio o0ｹ0 fi04o07 08o0307 02o07 000ｸ7030ｷ3apple 0ｸ802fi 040ｸ70702o07060400fi 020ｷ307 appleo03060206020607 0906 020907 02o06070ｷ30706026ｧ8 apple03o0402 046ｧ9. 09030602o07 fi04o07 08o0307 020907 02 02 appleo03 閨00090409 02o0ｸ7 appleo020300060400o6ｦ0 02 06 006ｦ0020003o07 fi04o07 08o0307 0209 000002 03036ｦ00300060409 020ｷ307 040ｸ70702 0106o o0206020607 040ｸ70402090007-020ｷ307. 0900 07 02o6ｧ9070ｷ30409 02090ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0, 09 oappleo6ｧ9 03 0ｸ7appleo6 5030903006ｧ9 apple030607 applefi 02o 02 閨03o0ｹ0 02o0ｸ7 閨02o0ｸ70ｹ0, 03 096ｧ907o0ｸ707 apple03o02070400060ｹ0 04040002060207 0000 020907 0ｸ7090006o07o0006026ｧ8 apple00036ｧ903 036 709, 06 6ｧ90ｷ30ｹ0 0000 6 5070409 02060ｹ0 appleo0306020602 閨0ｹ0 020ｷ307 0203 020607 0000030607 00 閨04 0402o apple03 6ｧ90406o 020ｷ307 0000-0907030ｷ307 0402fi040ｷ307 appleo0ｸ7 apple000306 閨0903 6 7 apple03o0909o0ｸ700 閨070ｷ30ｹ0. 05 apple03 鐶pple0006 020ｸ7036ｧ90ｷ30ｹ0 07 0402000802o6ｦ00000 02o0607o6ｦ00ｹ0 006ｧ90202000ｹ0, appleo0ｸ7 03 00apple06-0203 鐶ppleo0ｸ707 020907 appleo020003000400 0206026ｧ8 00 閨0203090409 02090ｹ0 apple03ofi o0ｸ7, 07 02 06 0400 000ｸ7030ｷ3apple 0ｸ802fi 00apple6ｧ9apple00 o 0ｸ702fi appleo0303 閨0ｹ0 08o03 閨0ｹ0 08 閨03070006 04020907 00apple060807070006 02o apple03fi6 5030900 02090ｹ0 閨030300066 7090ｹ0 apple03fi0408 020ｷ307, 0106fiapple0604020ｷ307 02 06 040ｸ70902036ｧ90406000ｷ307 00 o00 閨070ｷ307. 16 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13 ﾇ 06 040ｸ707o0306 026ｧ8 0007oappleo6ｧ9090409 020ｷ307 040ｸ70402090007020ｷ307 0ｸ7090006o07o0006026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0 6ﾑ86ｧ90200 apple03fi02000602 06 0906 020907 02060709020602fi020902 006ｧ90200 0906 0900070602fi020003 03 閨00 02 appleo0ｸ7 08o03o6ｦ007 02 040ｸ704026ｧ800 02 0ｸ709006ｧ9 0ｹ0, 006ｧ900 06 apple00060400 閨0709 fi0206 09 06 040ｸ707o0306 026ｧ8 040ｸ707000309 046ｧ9 00appleo03006ｧ9 07 06040006 040ｸ709020002030600 閨07000ｹ0 apple 07026ｧ80400060ｹ0 0402060ｹ0 040ｸ707 鐶pple0006000ｹ0 02090ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 o03o02036ｧ8-030ｷ304090ｹ0. 03020406, 02 ｨB09026ｧ800 02 appleo0ｸ7 apple03o 閨020ｸ76 7 07 applefi 02o0ｸ70ｹ0 000003o0306 02o6ｦ00ｹ0 000309 ｨBfi000007o0ｸ70ｹ0 閨02 07 07 02o 000ｸ7030ｷ3apple 0ｸ802fi 6ｧ902 06o 0906 020907 02o06070ｷ30706026ｧ8 apple03o0402 046ｧ9 07 apple03o040ｷ3036ｧ8040006. ﾞ0ｸ702fi 02o 06 040ｸ707o0306 02fi, 06 apple0003060800030006 02fi apple03 6ｧ90406o 006ｧ907 06 02o 02 02 03030903fi020003o 0906 07 00000300026ｧ804o0ｸ70000 036ｦ00400060ｹ0 02 06 07 0001 0408 036ｧ904o0ｸ70000 020907 070703096 709 020ｷ307 apple 070607 apple00036ｧ903 036 7090ｹ0 applefi 020907 07030309 apple03000ｸ70307 020ｷ307 040ｸ707fi030ｷ307, 030307 appleo0303 閨0ｹ0 08o03 閨0ｹ0 036ｧ909 00fi03060ｹ0 04060306fi00000203 applefi 020907 02 02o06026ｧ9 0007fi0ｹ0 02fi00o0ｸ7. ﾞ0ｸ702fi 0408 03060ｹ0 040900 6ｧ9070006 07 00000300026ｧ804o0ｸ70000 00 閨04 0402o apple03 6ｧ90406o 0ｸ702fi 020907 o030907070ｷ30409 02 06 02o 040400 06 0400fi 02090ｹ0 apple00036ｧ903 036 7090ｹ0, apple.04. 020907 02 02 07o006ｧ8 02o0ｸ7 0001oapple03060400o6ｦ0, 6ｧ8 02fi0009 02 06 0209 6 50003026ｧ90ｷ30409 020ｷ307 07o04o02o000006 020607 000902 02 04020704000ｷ307, 0100020607060702 0ｹ0 applefi 02 02006ｧ800 02 00apple000609fi07020ｷ307 apple0003060402 0206020607 02 06 02 00 06000ｸ7026ｧ80306, 0ｸ7apple090300046ｧ9000ｹ0 06 06 6ｧ9020003 000ｸ7 6ｧ904030902000ｹ0 02 06 040203 02090906026ｧ80ｹ0 040900 046ｧ9 0ｹ0. 6ﾒ2o 02 閨03 o0ｹ0 0906 02o0ｸ70ｹ0 02 02o6ｧ902o0ｸ70ｹ0 020ｷ307 apple000306o040607 0ｸ7020607 03 006ｧ907 06 apple03o08 07 閨0ｹ0, fiapple0ｷ30ｹ0 02 06 0906 02 o0602o07o00060207 020ｷ307 040ｸ709020002030600 閨070ｷ307 040ｷ3030607, appleo0ｸ7 03 00appleo03o6ｦ004 07 閨020406 07 00o0603 0402o6ｦ007 02o07 0203066 5fi 0001oapple03060400fi, fiapple0ｷ30ｹ0 006ｧ907 06 02 040ｸ704026ｧ800 02 06 020306026ｧ80ｹ0 apple000602fi070604090ｹ0, 0600o020703 0304090ｹ0 6ｧ8 02fi0009 02 06 00 06000ｸ70206026ｧ80ｹ0 6ｧ8 0700o0907o03o096ｧ9 0ｹ0. 6ｾ40ｸ700apple 閨03 0400 縺070ｷ3036ｧ9ｨB0ｷ3 fi0206 09 0ｸ709006ｧ9 006ｧ907 06 閨07 0ｹ0 02o00 陦 0ｹ0 0000 appleo036ｦ0apple03o02 02 06 04o6 5 0307 ｨB09026ｧ800 02, 0906 02 oappleo6ｧ9 0007 0ｸ7apple070304o0ｸ707 006ｦ002o03000ｹ0 02 06 appleo036ｦ0 apple0003060404fi020003o 03000ｷ30309020602 閨0ｹ0 apple 07026ｧ80400060ｹ0, 0209 04020609006ｧ8 000703060402 appleo0ｸ7 0402fi04o0ｹ0 020ｷ307 apple0306020ｷ307 00o03080607 02o06070ｷ30706026ｧ80ｹ0 apple03o0402 046ｧ9 0ｹ0 6ｧ802 07 09 00006ｧ90ｷ30409 02090ｹ0 030709040600fi020902 0ｹ0 02 06 09 0ｸ7090006o07o0006026ｧ8 apple00036ｧ903 036 709 apple 03 00 閨070006 閨07 applefi 02 040900 07020602fi020003 046ｦ0006 5o03 020ｷ307 00030706020607 00 0ｹ0 02o06070ｷ30706020607 040ｸ70402090007020ｷ307. 6ﾒ2 040ｸ704026ｧ800 02 0ｸ7090006o07o0006026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0 fi000ｷ30ｹ0 appleo0202o6ｦ007 fi03o 02 06 apple0003060404fi020003o 000ｸ7030ｷ3apple 0ｸ8026ｧ8 06070402-0409. 6ｾ402fi04o0ｹ0 02090ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 006ｧ907 06 fi0406 00fi07o 07 0207070006 0ｸ7026ｧ8 0209 06070402 0409 apple03 0900 020602fi020902 09 oappleo6ｧ9 07 0702 07 02030702 06 040209 07o00o03o096ｧ9 02o0ｸ7 040602 040209036ｧ9o0ｸ7, 030307 02 06 000309 03006ｧ9o 04020907 0ｸ7apple090300046ｧ9 02o0ｸ7 0002040ｸ7090403o07060400o6ｦ0, 02090ｹ0 appleo06fi020902 0ｹ0 02 06 02090ｹ0 o0602o07o0006026ｧ80ｹ0 6 5060ｷ3040600fi020902 0ｹ0. * fi090ｷ3 000202070202o0ｸ7 020ｷ3036ｦ000 02o0ｹ0 02090ｹ0 02 0ｹ0. 0406 00 0702oappleo6ｦ003o0ｸ7 09 o0006036ｧ9 閨09060700 applefi 02o07 02.. 09 0302oappleo0ｸ70306060209, 04/ 07026ｧ8 02090ｹ0 ﾞ070206apple03o040ｷ3apple006ｧ9 0ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 04020907 6ﾑ8030307 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 17

13EFPIA ANNUAL MEETINGS ATHENS 2003 6ｾ40ｸ707 0ｸ707ｨB080702 0ｹ0 0ｷ308 閨030006 0906 02080ｸ70ｹ0 04030007006ｧ90ｹ0 02 06 0806020807080006026ｧ8 000ｸ7030ｷ304026ｧ9 0906 020907 6ﾑ80ｸ70306apple09 O 0903fi00 03o0ｹ0 02090ｹ0 EFPIA, Sir Tom McKillop, 00apple06040900 6ｧ9070006 0209 ｨB0ｷ30206026ｧ8 0707090209 0906 09036ｧ809o0309 02 06 0604o0000036ｧ8 apple03fi046 5 0409 04020907 09o0307 020ｷ307 02 03apple0607 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 0303000ｸ707 0ｹ0 02 06 ﾞ0707apple020ｸ701090ｹ0 apple03o0ｹ0 fi080003o0ｹ0 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02090ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 08 0300 02o6 506o000904 076ｧ9 0ｹ0 030307 020ｷ307 0406030607 0ｷ307 6ﾑ80ｸ7030ｷ3apple 6ｧ90ｷ307 040300070607. ANNUAL MEETINGS 2003 ﾇ 0900fi0406 0ｸ709006ｧ9 6 5036ｧ904020002 06 04020907 02o030ｸ7086ｧ8 02090ｹ0 036ｧ90402 0ｹ0 apple03o020003 06o026ｧ8020ｷ307 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02ｨB 閨0702 0ｹ0, 000706 02 08070300 02 apple 03 00 閨07o0ｸ707 6 5 040602fi0ｹ0 apple 030709o0702 0ｹ0 0906 0209 6 50003026ｧ90ｷ30409 020ｷ307 apple03o04080003fi- 0000070ｷ307 0ｸ7apple09030004060607 0809006ｧ9 0ｹ0 0402o0ｸ70ｹ0 appleo036ｧ902000ｹ0. 6ﾑ86ｧ907 06 090009o07fi0ｹ0 fi0206 09 6ﾑ80ｸ70306apple09 6 5 046ｧ9ｨB0002 06 040209 08 0300 02o6 506o000904 076ｧ9 0906 00apple0007 6ｦ00400060ｹ0 0400 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109 06040200 07 0001 0408 03060403006ｧ9 09 03o6ｧ8 apple 03 090ｷ3096ｧ80ｹ0 07 閨0ｷ307 00010003060900 閨070ｷ307 08 0300 02000ｸ70206020607 apple03o0ｸ8fi07020ｷ307 0402o 00 閨0303o07. 6ﾑ8 06, 04020907 ﾞ036ｧ807, 040209 040ｸ707070702090409 0906 02 25 0403fi0706 02090ｹ0 EFPIA, 0906o030207ｨBo0ｸ70000 0000030602 閨0ｹ0 applefi 02060ｹ0 000009 036ｦ0020003000ｹ0 040ｸ70700060408o03 閨0ｹ0 appleo0ｸ7 閨090607 07 0402o apple 03000303fi07 040209 08 0300 02000ｸ70206026ｧ8 閨03000ｸ707 02 06 03 000100020704o0ｸ70000 02060ｹ0 apple06o 0007 06 08 閨03o0ｸ704000ｹ0 000100036ｧ90100060ｹ0 02o0ｸ7 00 閨0303o0702o0ｹ0. 00 ﾞ0ｸ7026ｧ8 09 apple00036ｧ9o o0ｹ0 006ｧ907 06 appleo036ｦ0 0007 06 08 閨03o0ｸ704 0906 fi04o0ｸ70ｹ0 0404o03o6ｦ00702 06 0000 0209 08 0300 02000ｸ70206026ｧ8 閨03000ｸ707 03 00apple06040900 6ｧ9070006 o Sir Tom McKillop, apple03fi00 03o0ｹ0 02090ｹ0 EFPIA. 006ﾒ2 00apple0604020900o07060207 02 06 02000407o03o09060207 00apple0602006ｦ00900 02 6ｧ907o0ｸ707 0209 0ｸ707 02fi020902 0402o0ｸ70ｹ0 0003000ｸ7070902 閨0ｹ0 07 0402o04006ｦ0o0ｸ707 0400 fi03o 02 06 apple06o appleo036ｦ0apple03o02000ｹ0 030306040206000ｹ0. ﾇ apple03 0900 0206026ｧ8, fi000ｷ30ｹ0, 040ｸ70700060408o0307 020ｷ307 08 0300 02000ｸ70206020607 0002 060300060607 04020907 06 020306026ｧ8 apple03fio o, 03 006ｧ907 06 07 000002 0203 閨6 7o0ｸ707 02060ｹ0 07 02 036ｦ06 700060ｹ0 020ｷ307 0003000ｸ7070607 0400 apple030ｷ302oappleo0306 02 閨0ｹ0 030003 apple006ｧ9000ｹ0 appleo0ｸ7 03 006ｧ907 06 000ｸ703 閨0ｷ30ｹ0 06 03 閨040600000ｹ0 0402o 02o0607fi03. 0906 apple030ｷ302oappleo0306 026ｧ8 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9 0007 03 apple 6ｧ9ｨB0006, apple0307, 040900 07020602fi 03fi03o 040209 6 50003026ｧ90ｷ30409 020ｷ307 000ｸ7030ｷ3apple 0ｸ8020607 apple03o 06 0903 080607 0ｸ709006ｧ9 0ｹ0, 030307 02 06 03 040ｸ70700060408 閨030006 02 00 閨09060402 04020907 000ｸ7030ｷ3apple 0ｸ8026ｧ8 o0602o07o006ｧ9, 000ｸ7090000036ｧ9 02 06 0402 030003fi020902 020ｷ307 020ｸ76 50003076ｧ804000ｷ307 02 06 020ｷ307 appleo0306020607. 030402fi04o, 03 apple03 鐶pple0006 07 020003o6ｦ007 0207appleo06o06 apple03o6 5030900 02060400o6ｧ9 04040002060207 0000 02o 000707 閨04o0ｸ707 03090803006ｧ9 o06 040ｷ30402 閨0ｹ0 appleo08070400060ｹ0 0906 00000303o07020602 閨0ｹ0 00apple0007 6ｦ00400060ｹ0 0402o07 02o00 陦 apple 03o046ｧ80ｹ0 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 08 0300 02o6 506o000904 076ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09. ﾇ 08 0300 02000ｸ70206026ｧ8 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109 006ｧ907 06 0006 03 0402090306fi020902 0000 0000090703o 02fi0402o0ｹ0 02 06 036ｧ90402o. 6ﾑ80706 o 00 閨04o0ｹ0 fi03o0ｹ0 0707apple020ｸ701090ｹ0 08 030007020ｷ307 006ｧ907 06 10-12 0403fi0706 0000 02fi0402o0ｹ0 895 0002 02. 6ﾑ80ｸ70306, 0007 0ｸ7apple0703040006 apple03 0900 0206026ｧ8 0009096ｦ0090409 0906 00apple06020ｸ7046ｧ9. 006ﾒ2 閨02o06 02fi040209 00appleo03o6ｦ007 07 06 0209030903o6ｦ00703, 03 閨0006 o Sir Tom, 0000fi07o 0400 閨07 02036ｧ900 appleo0ｸ7 03 000ｸ707o006ｧ9 020907 02 0607o02o006ｧ9, apple 03 閨04o0702 0ｹ0 026ｧ907090203 02 06 0ｸ7appleo04026ｧ8-03060109 0906 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109, 000706 02 0ｸ702fi0403o07 03 090006o0ｸ70309006ｧ9 04020907 09o0307 閨07 apple0003066 5070303o07 appleo0ｸ7 03 00apple060203 鐶pple0006 0209 09036ｧ809o0309 02 06 0604o0000036ｧ8 apple03fi046 5 0409 0402 apple03o0ｸ8fi0702 0ｸ7026ｧ80ｹ0 02090ｹ0 閨03000ｸ707 0ｹ0. 6ﾑ86ｧ907 06 030ｸ7apple0903fi 02o 090009o07fi0ｹ0 fi0206 09 6ﾑ80ｸ70306apple09 006ｧ907 06 020003000ｸ702 6ｧ9 030609fi020003o 0003020ｸ7040206026ｧ8 09o0307 0906 00apple0007 6ｦ00400060ｹ0 0400 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109, 0400 0404 閨0409 0000 02060ｹ0 ﾇ09 ﾞ, 000706 09 6ｦ007 0009 02090ｹ0 000ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6 50704090ｹ0 0303000ｸ707 0ｹ0 02 06 ﾞ0707apple020ｸ701090ｹ0 0402 06 0207 06 6 50306070002 06. ﾇ 08 0300 02o6 506o000904 076ｧ9 02 030ｷ304o036ｧ9ｨB0006 18 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13020907 000ｸ702 06036ｧ9 0906 00appleo0602o o0009020602fi 060703o09o appleo0ｸ7 090006o0ｸ703096ｧ803090200 applefi 02o G10, 0ｷ30ｹ0 apple070702090409 040209 09000706026ｧ8 0709040ｸ7046ｧ9 appleo0ｸ7 apple03o02036ｧ803090200 applefi 020907 0207006 709 02090ｹ0 0702 090ｷ3070604020602fi020902070ｹ0 02090ｹ0. 6ﾒ20603 006ｧ907 06 09 04020609006ｧ8 0906 fi03o0ｸ70ｹ0 02o0ｸ70ｹ0 0000apple030002fi000007o0ｸ70ｹ0 07 040ｸ70700046ｧ904o0ｸ707 02o 060703o09o 06040200 o06 040ｸ70402070400060ｹ0 02o0ｸ7 G10 07 000002 0203 appleo6ｦ007 0400 apple0307010903, 03 閨0006 o Sir Tom. ﾇ 07 02o6ｧ9070ｷ30409 02090ｹ0 ﾒo00060406fi07, appleo0ｸ7 07 00 閨070002 06 0000 02fi04o 0007 06 08 閨03o07, 03 006ｧ9010006 applefi04o 02 0307 apple03o0002o0600 0400 閨0709 006ｧ907 06 09 6ﾑ80ｸ70306apple09 07 07 0207006 70006 applefi 020907 6ｦ008000409 02 06-040ｸ709020002030600 閨07-000707 006ｧ907 06 閨02o060009 07 0702060000020ｷ3apple6ｧ9040006 02060ｹ0 07020601ofi020902000ｹ0 02090ｹ0 09o03070ｹ0 02 06 020907 070604o0000036ｧ8 apple03fi046 5 0409 0400 07 陦 08070300 02 appleo0ｸ7 apple03o02 03006ｧ902 06 applefi 020907 閨030300066 709 0006 0ｹ0 000706 6ｧ9 0ｹ0 09o03070ｹ0 0402 08070300 02. ﾇ 08 0300 02o6 506o000904 076ｧ9 0403000607ｨB0002 06 閨07 030004000602fi apple03 6ｧ90406o apple 0902fi040006o0ｸ7 6 5000309070002o6ｦ00ｹ0 apple03o02000600 閨07o0ｸ7 07 apple 03 閨040006 0402060ｹ0 00apple06040006036ｧ80400060ｹ0 02o0ｸ7 020307 o0ｸ7 0402 030003fi020902 02 06 09036ｧ809o0309 apple03fi046 5 0409 04020907 09o0307. ﾞ030307 02o 6ｧ9 06o 0604046ｦ00006 02 06 0906 02o07 040300076ｧ8, 02 03060ｹ0, fi04o apple06o appleo020003000400 020602o6ｧ9 006ｧ907 06 o06 02 07fi07000ｹ0, 02fi04o 000009 036ｦ002000309 0ｸ707 02fi020902 閨040006 o 040300076ｧ80ｹ0 0906 apple06o 09036ｧ809o0309 02 06 0002020002 00 閨0709 apple03fi046 5 0409 0402 o08 閨0309 07 閨0ｷ307 030003 apple00060607. ﾞapplefi 020907 1 09 0ｹ1o0ｸ7 2004 03 006ｧ907 06 apple0003060404fi020003o 040900 07020602fi applefi appleo02 07 06 0408 036ｧ904o0ｸ70000 fi0206 o06 02 03appleo6ｧ9 020ｷ307 00apple0007 6ｦ004000ｷ307 02090ｹ0 08 0300 02o6 506o000904 076ｧ9 0ｹ0 03 06 00o060307ｨBo0702 06 6ｧ902 06 0400 0006 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 ﾒo0607fi020902 25 0000030607, 0000 appleo036ｦ0 040900 07020602 閨0ｹ0 06 08o03 閨0ｹ0 0ｷ30ｹ0 apple03o0ｹ0 020907 o0602o07o0006026ｧ8 02o0ｸ70ｹ0 02 02070402 040903. 6ﾒ2 閨03o0ｹ0, o Sir Tom McKillop 02 02 036ｧ8090006: 000906 0604040ｸ7036ｧ8 08 0300 02o6 506o000904 076ｧ9 0906 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409 appleo020003006ｧ9 02030006 6ｧ9 0906 020907 o0602o07o0006026ｧ8 00apple06020ｸ7046ｧ9 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 046ｧ8000003 02 06 030000 閨0306o 0906 0006 02 036ｦ002000309 0ｸ709006ｧ9 0906 fi03o0ｸ70ｹ0 02o0ｸ70ｹ0 6ﾑ80ｸ7030ｷ3apple 6ｧ9o0ｸ70ｹ0 6ｦ00306o. 6ﾑ86ｧ907 06 0402o 04 閨0306 fi030ｷ307 00 0ｹ0-020ｸ76 50003076ｧ804000ｷ307, 07o00o0300020607, 6 506o000904 076ｧ9 0ｹ0, 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0 02 06, apple07070ｷ3 applefi fi03, 040300070607-07 o0ｸ703 閨6 7o0ｸ70000 00 ｨB6ｧ9 06040200 07 apple03 0900 020604o0ｸ70000 0006 0ｸ709066ｧ8 08 0300 02o6 506o000904 076ｧ9 apple03o0ｹ0 fi080003o0ｹ0 020ｷ307 450 0002 02o00000ｸ7036ｧ90ｷ307 appleo0306020607 02090ｹ0 06000ｸ7030ｸ700 閨07090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ003. 006ﾒ2o 02030006 6ｧ9 02090ｹ0 040ｸ70700060408o03070ｹ0 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 006ｧ907 06 07 000002o0ｸ7040606070006 02 040900 0702060207 000ｸ7036ｧ800 02 02090ｹ0 閨03000ｸ707 0ｹ0 0400 apple030ｷ302oappleo0306 02 閨0ｹ0 030003 apple006ｧ9000ｹ0 appleo0ｸ7 03 00appleo03o6ｦ007 07 006ｧ907 06 02 06 000ｸ703 閨0ｷ30ｹ0 06 00 o00 閨07000ｹ003 ﾞapplefi 080409 02000600 閨07080ｸ7 09. 09 03020002070209 Public Relations Officer (Roche) 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 19

13EFPIA ANNUAL MEETINGS ATHENS 2003 G-10 ﾌ0007 086 70903086ｦ0 6ﾑ8apple06apple 陦080ｸ7 G-10 ﾌ0007 086 70903086ｦ0 6ﾑ8apple06apple 陦080ｸ7 0906 020907 02 0607080208006ｧ9 02 06 02 08070300 02 0906 020907 02 0607080208006ｧ9 02 06 02 08070300 02 ﾇ O0007 086 70903o6ｦ0 6ﾑ8apple06apple 陦o0ｸ7 0906 020907 02 0607o02o006ｧ9 02 06 02 08070300 02 09 00appleo07o00 ｨBfi- 00000709 G-10 appleo020003006ｧ9 020907 apple070702090409 04020907 09000706026ｧ8 0709040ｸ7046ｧ9 0906 020907 appleo 0ｸ70707000ｷ30409 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 08 0300 02o6 506o000904 076ｧ9 0ｹ0. ﾇ o0007 G-10 appleo020003006ｧ902 06 applefi 02o0ｸ70ｹ0 00apple6ｧ90203oappleo0ｸ70ｹ0 Erkii Liikanen 縺0007. 04/07046ｧ8 6ﾑ8apple06040006036ｧ804000ｷ307 02 06 09030903o08fi030904090ｹ0 02 06 David Byrne 縺0007. 04/070409 0809006ｧ9 0ｹ0 02 06 0903o0402 046ｧ9 0ｹ0 ﾒ 02 07 030ｷ3020607, 02o0ｸ70ｹ0 08appleo0ｸ70309o6ｦ00ｹ0 apple 閨070200 ﾒ03 020607-0900030607 ( 罍 03036ｧ9, 縺000300 076ｧ9, 09o0302o09 036ｧ9, 6ｾ4o0ｸ709 6ｧ9, ﾇ07. 08 046ｧ9030006o) 0002apple03o0406appleo0ｸ70ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 02 06 0703030ｷ307 0007 06 080003fi0000070ｷ307 0000030607. ﾇ o0007 apple 03o0ｸ7046ｧ9 0400 020907 000003 閨0209 02090ｹ0 0402o07 0903fi00 03o 02090ｹ0 Commission Romano Prodi (090706o0ｹ0 2002) 02 06 0402o 6ｾ40ｸ7006 5o6ｦ00306o 08appleo0ｸ703090607 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0 (ｦﾐo6ｦ00706o0ｹ0 2002). ﾇ 000003 閨0209 appleo020003006ｧ902 06 applefi 14 040ｸ70402070400060ｹ0 (recommendations) 0000030602 閨0ｹ0 applefi 02060ｹ0 oappleo6ｧ9000ｹ0 apple 03o0ｸ7040607ｨBo0ｸ707 0000090703o 0007 06 08 閨03o07 0906 0209 6 506o000904 076ｧ9. O06 14 040ｸ70402070400060ｹ0 006ｧ907 06: 09 H 6ｾ46ｦ00402 0409 I ｨB0902006ｧ9 020907 02 020206026ｧ8 apple 03 02o03o6ｦ003090409 020ｷ307 04000602020607 6ｾ40ｸ7090203060206026ｧ80ｹ0 ﾞ0106o03fi090904090ｹ0 (benchmarking and performance indicators) 02090ｹ0 applefi o04090ｹ0 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 0400 0404 閨0409 0000 02o0ｸ70ｹ0 006ｧ90202000ｹ0 6 506o000904 0706026ｧ80ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 020907 apple03fi03096 709 02 06 030003 apple006ｧ9 07fi040ｷ307 02 06 020607 6ｦ0070ｷ307 appleo0ｸ7 apple000603o6ｦ007 020907 0ｸ709006ｧ9 0000 07 08o0307 0400 00 o00 閨07 07o040903fi020902 0ｹ0, 040ｸ700apple00030603 006 50707o0702 0ｹ0 020907 appleo020003000400 020602fi020902 020ｷ307 08 0300 02000ｸ70206020607 apple03o0ｸ8fi07020ｷ307 0209 0404 閨0409 000002 016ｦ0 02090ｹ0 o006ｧ80ｹ0 020ｷ307 O0309 070604000607 6ﾑ80902036ｧ904000ｷ307 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 02 06 020ｷ307 ﾒ03 020607-0900030607 (0906 0209 04o036ｧ809090409 07 0006 0ｹ0 020ｸ70203o08o036ｧ9 0ｹ0, 02o07 02 03o03060400fi 0206006ｧ80ｹ0 02 06 020907 0207030ｸ76 709 applefi 020907 02o06070ｷ30706026ｧ8 040807-03060409) 02 06 02090ｹ0 apple03fi046 5 04090ｹ0 020ｷ307 040300070607 0402 07 陦 08070300 02 (0403fi07o0ｹ0 appleo0ｸ7 apple 0602006ｧ902 06 0906 020907 閨090203060409, 0403fi07o0ｹ0 appleo0ｸ7 apple 0602006ｧ902 06 0906 020907 020ｸ70203o08o036ｧ9 04020907 09o0307). 09 ﾇ 6ｾ46ｦ00402 0409 ｦﾐｦﾐ ｨB0902006ｧ9 02 046ｦ0020003000ｹ0 06 0602 046ｧ9000ｹ0 閨0902030604090ｹ0 0906 07 6 5000302060ｷ303006ｧ9 09 006ｧ904o o0ｹ0 020ｷ307 07 閨0ｷ307 08 030007020ｷ307 04020907 09o0307. 04090006o0ｸ703096ｧ9 02 04006ｧ9 0ｹ0 06 0602 046ｧ9 0ｹ0 閨0902030604090ｹ0 0906 08070300 02 appleo0ｸ7 006ｧ907 06 040900 0702060207 applefi 07appleo6 709 040900fi0406 0ｹ0 0809006ｧ9 0ｹ0. 6ｾ40ｸ70702fi00000ｸ70409 02090ｹ0 06 0602 046ｧ9 0ｹ0 036ｧ86 7090ｹ0 appleo080704000ｷ307 (decision making process) 0903 6ｧ8 02o0ｸ7 0403fi07o0ｸ7 appleo0ｸ7 apple 0602006ｧ902 06 (02 0207 020907 閨090203060409 020ｷ307 08 030007020ｷ307 0000 020007020306026ｧ8 06 0602 046ｧ9 ) applefi 020907 09070ｷ300o fi02090409 02090ｹ0 CPMP (02o0607o0206026ｧ8 00apple060203oapple6ｧ8 閨0902030604090ｹ0 08 030007-020ｷ307) 00 閨040306 020907 閨02 o0409 02090ｹ0 07 0006 0ｹ0 020ｸ70203o08o036ｧ9 0ｹ0 applefi 020907 Commission. 09 ﾇ 6ｾ46ｦ00402 0409 ｦﾐｦﾐｦﾐ ｨB0902006ｧ9 applefi 02 ﾒ03070209-09 閨0309 07 040ｸ70702o00006ｦ004o0ｸ707 02o 0403fi07o appleo0ｸ7 000004o03 6 5006ｧ9 applefi 020907 04o036ｧ809090409 02090ｹ0 07 0006 0ｹ0 020ｸ70203o08o036ｧ9 0ｹ0 0007fi0ｹ0 08 03000702o0ｸ7 00 閨040306 07 02 03o03060402006ｧ9 09 0206006ｧ8 02o0ｸ7 02 06 07 000702 0403006ｧ9 04020907 036ｧ90402 020ｷ307 08 030007020ｷ307 appleo0ｸ7 02 036ｦ0apple02o0702 06 applefi 020907 02o06070ｷ30706026ｧ8 04080703060409. ﾇ O 09096ｧ9 89/105 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 apple03o6 503 鐶pple0006 fi0206 o06 06 0602 046ｧ9000ｹ0 02 03o03060400o6ｦ0 0206006ｧ80ｹ0 02 06 閨0702 01090ｹ0 020ｷ307 08 030007020ｷ307 040209 036ｧ90402 apple03 鐶pple0006 07 o03o020309030607o0702 06 000702fi0ｹ0 180 090000030607. 09 H 6ｾ46ｦ00402 0409 ｦﾐV apple00030603 006 507070006, 0007030703030ｸ7070409 0906 020907 040ｸ70702 09o09030708090409 generics 0906 07 0ｸ7010903006ｧ9 09 06006ｧ904 0ｸ70409 generics 04020907 09o0307. ﾌ6ﾑ8apple6ｧ9020308apple080ｹ0 Erkii Liikanen 20 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13 ﾌ6ﾑ8apple6ｧ9020308apple080ｹ0 David Byrne 09 ﾇ 6ｾ46ｦ00402 0409 VI appleo020003006ｧ9 02o apple030602o 6 56ｧ800 0906 0006 000706 6ｧ9 09o0307 08 030007020ｷ307 0000 6 5070409 02o07 0702 090ｷ307060400fi (competition based). To 040200apple020602fi 02090ｹ0 046ｦ00402 04090ｹ0 006ｧ907 06 fi0206 09 0300o 06fi020902 0007fi0ｹ0 ﾒ030702o0ｸ70ｹ0/09 閨03o0ｸ70ｹ0 0906 02o07 02 03o03060400fi 02090ｹ0 0206006ｧ80ｹ0 020ｷ307 08 030007-020ｷ307 apple03 鐶pple0006 07 08o0307 00fi07o 02 08070300 02 appleo0ｸ7 02 036ｦ0apple02o0702 06 applefi 02o06070ｷ30706026ｧ8 04080703060409 6ｧ8 appleoｨb0900060607o0702 06 applefi 02o ﾒ030702o0ｹ0. ﾞ0ｸ702fi 040900 6ｧ9070006 02 02070309090409 02o0ｸ7 0003 閨0904o0ｸ7 0206000607 0906 : 09 6ﾒ2 OTC 09 6ﾒ2 08070300 02 appleo0ｸ7 0007 02 036ｦ0apple02o0702 06 applefi 020907 02o06070ｷ30706026ｧ8 04080703060409 09 6ﾒ2060ｹ0 apple0ｷ3036ｧ80400060ｹ0 08 030007020ｷ307 0402o07 06 060ｷ3020602fi 02o00 陦 09 ﾇ 6ｾ46ｦ00402 0409 VII 07 08 閨030002 06 040209 0404 閨0409 02fi0402o0ｸ70ｹ0- appleo020003000400 020602fi020902 0ｹ0 02 06 apple03o6 503 鐶pple0006 020907 0707apple020ｸ70109 02090ｹ0 0106o03fi090904090ｹ0 02090ｹ0 02000407o03o096ｧ9 0ｹ0 0ｸ709006ｧ9 0ｹ0 (health technology assessment). 09 O06 6ｾ40ｸ70402070400060ｹ0 VIII 02 06 IX 07 08 閨03o0702 06 04020907 0707apple020ｸ70109 02090ｹ0 閨03000ｸ707 0ｹ0 02 06 04020907 0707090209 07 040ｸ70402 03006ｧ9 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi0ｹ0 O0309 07060400fi0ｹ0 070703o09o0ｹ0 02o0ｸ7 National Institute of Health 020ｷ307 ﾇ09 ﾞ, 0906 020907 0ｸ7appleo04026ｧ803060109 02090ｹ0 0707apple020ｸ701090ｹ0 o0308 070607 08 030007020ｷ307, 08 030007020ｷ307 0906 apple 06 06 020306026ｧ8 04036ｧ80409 02 06 0906 020907 0707apple020ｸ70109 04020907 6ﾑ80ｸ70306apple09 6ｾ40203 02090906026ｧ80ｹ0 0906 0209 0806o02000407o03o096ｧ9. 09 ﾇ 6ｾ46ｦ00402 0409 X 07 08 閨030002 06 04020907 apple 03o046ｧ8 apple030903o08o03060607 0402o0ｸ70ｹ0 04030007006ｧ90ｹ0. ﾆ0902006ｧ9 07 040ｸ7070004060402006ｧ9 09 apple 09fi03000ｸ70409 02090ｹ0 06 086ｧ8000604090ｹ0 020ｷ307 08 030007020ｷ307 appleo0ｸ7 04o030909o6ｦ00702 06 0000 06 020306026ｧ8 040ｸ70702 096ｧ8 02 06 07 040ｸ700080ｷ3070903006ｧ9 apple03 020206026ｧ8 06070203060409 000002 016ｦ0 06 086ｧ8000604090ｹ0 02 06 apple030903o08fi030904090ｹ0. 09 ﾇ 6ｾ46ｦ00402 0409 XIV 07 08 閨030002 06 040209 06006ｦ0030ｸ7070409 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 02 06 ｨB0902006ｧ9 07 apple00-030603090803006ｧ9 0402060ｹ0 6ｾ40ｸ707036ｧ802000ｹ0 閨0702 01090ｹ0 020ｷ307 07 閨0ｷ307 ﾒ03 020607-0900030607 0006 06026ｧ8 0007006ｧ9 06040200 02 0207 apple 03 閨020203060409 020ｷ307 06 020701000ｷ307 07 000907 096ｧ907o0702 06 apple 030703030903000ｹ0 000604 090ｷ309 閨0ｹ0 applefi 02 ﾒ03070209 0ｸ70207. O06 06 apple03 0900 02006ｦ00400060ｹ0 appleo0ｸ7 閨04o0ｸ707 096ｧ9070006 00 閨040306 046ｧ8000003 02 036ｦ0apple02o0ｸ707 00fi07o 02 08070300 02 0906 02 oappleo6ｧ9 09 apple00036ｧ9o o0ｹ0 apple03o0402 046ｧ9 0ｹ0 02090ｹ0 apple07000ｸ700 0206026ｧ80ｹ0 06 06o020209046ｧ9 0ｹ0 (apple 02 閨0702 ) 0402060ｹ0 0ｸ7applefi 閨0702 0109 040603000ｹ0 006ｧ907 06 06 08o03000206026ｧ8 applefi 0ｸ7026ｧ8 appleo0ｸ7 0604046ｦ00006 0402 ﾒ03070209-09 閨0309 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0. O06 0ｸ7applefi03o06apple000ｹ0 040ｸ70402070400060ｹ0 08o03o6ｦ007 020907 0ｸ702o030003 apple006ｧ9 (OTC) 6ｾ46ｦ00402 0409 V, 02 086ｦ00303 o 0909060607 04036ｧ804000ｷ30ｹ0 0906 02o0ｸ7 04030007006ｧ90ｹ0 6ｾ46ｦ00402 0409 01I, 020907 apple 03 02o03o6ｦ003090409 020ｷ307 08 030007020ｷ307 00000207 020907 020ｸ70203o08o036ｧ9 02o0ｸ70ｹ0 (post marketing surveillance), 6ｾ46ｦ00402 0409 01II 02 06 020907 apple 03o046ｧ8 6 5 0406026ｧ80ｹ0 00apple0604o036ｧ8090904090ｹ0 (core- funding) 0400 o0007 000ｹ0 040300070607 6ｾ46ｦ00402 0409 01III. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 21

13EFPIA ANNUAL MEETINGS ATHENS 2003 6ｾ404 陦06o 000700030900060607 02090ｹ0 Commission 02090ｹ0 Commission H 000003 閨0209 02090ｹ0 O0007 0ｹ0 086 70903o6ｦ0 6ﾑ8apple06apple 陦o0ｸ7 0906 020907 02 0607o02o006ｧ9 02 06 02 08070300 02 (G10) appleo020003006ｧ9 00 閨03o0ｹ0 0007fi0ｹ0 000ｸ7036ｦ0020003o0ｸ7 040400 6ｧ9o0ｸ7 000700030900060607 02090ｹ0 Commission 0906 020907 6 50003026ｧ90ｷ30409 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09. O06 08appleo0ｸ70309o6ｧ9 0806o000904 076ｧ9 0ｹ0 ｨB6ｧ8020904 07 applefi 020907 Commission 07 apple03o040ｷ3036ｧ8040006 04020907 000003 閨0209 020ｷ307 04000602020607 ﾞ0106o03fi090904090ｹ0 (Benchmarking indicators) 0304o0ｸ707 6ｧ8 09 03o00o03o090903006ｧ9 applefi 020907 Commission o06 00016ｧ80ｹ0 apple030ｷ302o6 5o0ｸ7036ｧ9000ｹ0: 09 6ｾ402060ｹ0 26 03o00006 5036ｧ9o0ｸ7 2002 02o 6ｾ40ｸ7006 5o6ｦ00306o 020ｷ307 08appleo0ｸ703090607 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 0906 020907 00 ﾞ0702 090ｷ3070604020602fi020902 03 0ｸ706o03 閨02090400 02o 0404 陦06o 030704090ｹ0 appleo0ｸ7 0002applefi07090400 09 Commission 0906 020907 0ｸ7appleo04026ｧ803060109 02090ｹ0 0707apple020ｸ701090ｹ0 02090ｹ0 6 506o02000407o03o096ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09 (Commission Communication on Life Sciences and Biotechnology in Europe). 09 ﾇ 07 03000603090409 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 07o00o0300046ｧ9 0ｹ0-O06 apple03o02070400060ｹ0 02090ｹ0 Commission 040ｸ7ｨB0902o6ｦ00702 06 0402o 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi ﾒo0607o6 5o6ｦ00306o 02 06 02o 6ｾ40ｸ7006 5o6ｦ00306o 08appleo0ｸ703090607. 09 ﾇ Commission 6 503 鐶pple0006 0209 000003 閨0209 G10 fi0406 04 07 000000o070ｷ300 閨0709 apple030ｷ302o6 5o0ｸ7036ｧ9 030307 04 07 閨07 appleo0306020602fi forum 0906 020907 046ｦ0090203060409 020ｷ307 03 閨04000ｷ307 020ｷ307 0007 06 080003o00 閨070ｷ307 0000030607 046ｦ000080ｷ307 0000 020907 040203 02090906026ｧ8 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0 (Lisbon strategy). ﾞ0106o03fi09090409 02090ｹ0 EFPIA ﾞ0106o03fi09090409 02090ｹ0 EFPIA ﾇ EFPIA apple060402006ｦ00006 fi0206 02o G10 appleo020003006ｧ9 閨07 forum 040ｸ7ｨB09026ｧ804000ｷ307 0402o oappleo6ｧ9o o06 040ｸ700000002 閨04o0702000ｹ0 000400006ｦ0o0702 06 0906 02o 046ｦ007o03o 020ｷ307 040ｸ704020704000ｷ307. O06 040ｸ70402070400060ｹ0 0ｸ702 閨0ｹ0 0007 00appleo03o6ｦ007 07 0008 0300o0403o6ｦ007 appleo04apple 0400 02060207. O06 040ｸ70402070400060ｹ0 6ｧ9 o0ｸ707 閨0008 0409 04020907 00076ｧ904040ｸ70409 02090ｹ0 0702 090ｷ3070604020602fi020902 0ｹ0 02 06 00appleo03006ｧ9 07 6 5000302060604o0ｸ707 02o apple0003066 5070303o07 00 閨04 0402o oappleo6ｧ9o 03000602o0ｸ70309006ｧ9 09 6 506o000904 076ｧ9. 縺06 07 000703 03030ｸ70703006ｧ9 09 閨03000ｸ707 02 06 0707apple020ｸ70109 07 閨0ｷ307 08 030007020ｷ307 apple 0602006ｧ902 06 apple03o0402 046ｧ9 02090ｹ0 apple07000ｸ700 0206026ｧ80ｹ0 06 06o020209046ｧ9 0ｹ0 02 06 020ｸ70203o08o036ｧ9 020ｷ307 07 閨0ｷ307 08 030007020ｷ307 0400 fi0309 020907 6ﾑ80ｸ7-0306apple09 0000 020907 apple03 鐶ppleo0ｸ704 0206006ｧ8 (equitable price). 09 03 00 閨070006 fi000ｷ30ｹ0 02o 026ｦ00306o apple03fi6 5030900, o 02 02 02000300 02060400fi0ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 09o03070ｹ0 appleo0ｸ7 o 0909006ｧ9 0402o apple 030703030903o 0000applefi0306o. ﾇ 02 02070402 0409 00apple06 00060706070002 06 0000 02060ｹ0 000006060400060ｹ0 0206000607 appleo0ｸ7 00o07o000003060ｹ0 00apple066 5070303o0ｸ707 ﾒ03070209-09 閨0309 02 06 0000 020907 00apple0602006ｧ900000709 06006ｦ0030ｸ7070409 02090ｹ0 6ﾑ8. 03070ｷ304090ｹ0. ﾇ 0702 090ｷ3070604020602fi0209-02 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 03 00070604040ｸ703006ｧ9 00fi07o 000707 030ｸ703o6ｦ007 02 apple03o6 5036ｧ800 02 appleo0ｸ7 090006o0ｸ70309006ｧ9 09 07020608 0206026ｧ8 appleo03060206026ｧ8 appleo0ｸ7 02o03o0ｸ703o6ｦ007 09 6ﾑ8. 03070ｷ30409 02 06 02 ﾒ03070209-09 閨0309 0400 0003070602fi 00apple6ｧ9apple00 o. ﾇ 000003 閨0209 G10 appleo020003006ｧ9 閨07 6 56ｧ800 0906 020907 02 0306 閨030ｷ30409 6 506o000904 0706026ｧ80ｹ0 appleo03060206026ｧ80ｹ0 04020907 6ﾑ80ｸ70306apple09. 0903fi0903 0000 000700030900060607 000700030900060607 G10 G10 6ﾒ2o07 ｦﾐo6ｦ00706o 2003 03 0002 o03006ｧ9 00 ﾞ07 02o6ｧ9070ｷ30409 02090ｹ0 Commission03 (Communication) 09 oappleo6ｧ9 03 appleo020003006ｧ9 020907 00apple6ｧ904090009 apple07070209046ｧ8 02090ｹ0 0402060ｹ0 040ｸ70402070400060ｹ0 G10. ﾇ EFPIA 07 00-070006 020907 07 02o6ｧ9070ｷ30409 02090ｹ0 Commission 06040200 o06 00040ｸ70402070400060ｹ003 07 apple0703o0ｸ707 020907 00o03086ｧ8 apple03 020206020607 00 閨02030ｷ307 appleo0ｸ7 03 040ｸ7006 5070303o0ｸ707 030002060207 040209 090006o0ｸ703096ｧ9 apple0003066 5070303o0702o0ｹ0 appleo0ｸ7 03 000ｸ707o006ｧ9 020907 閨03000ｸ707 04020907 6ﾑ80ｸ70306apple09. 6ﾒ2o07 ｦﾐo6ｦ00306o 2003 09 Commission 03 o0309 0706040006 6ｾ40ｸ707 陦0306o 0400 040ｸ707000309 046ｧ9 0000 020907 ｦﾐ02 0306026ｧ8 0903o00 036ｧ9 080600030ｷ300 閨07o 0402o G-10. ﾞapplefi o0409 02090ｹ0 apple 03o0ｸ7046ｧ9 04090ｹ0 02o0ｸ7 6ﾑ8apple060203fiappleo0ｸ7 Liikanen, 6ｾ4. 09000307 04/07020306 6ﾑ8apple0604020900080706020607 03000007020ｷ307 22 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13 ﾞ070604fi020902000ｹ0 04020907 0903fi046 5 0409 020ｷ307 6ﾑ80ｸ7030ｷ3 ﾞ070604fi020902000ｹ0 04020907 0903fi046 5 0409 020ｷ307 6ﾑ80ｸ7030ｷ3apple 6ｧ90ｷ307 ﾞ040300070607 0402 0402 07 陦 08070300 02 07 陦 08070300 02 ﾞapplefi04apple 0400 applefi 020907 apple 03o0ｸ7046ｧ9 0409 02o0ｸ7 ﾞ070206apple03o 陦03o0ｸ7 02090ｹ0 EFPIA Jean-Fran04ois Dehecq Belgium Greece Portugal France Austria Finland Italy Norway Spain Netherlands Switzerland Sweden Denmark Ireland UK ﾒ ﾞ05086ｾ46ﾒ26ﾑ806 ﾇ6ｾ4 ﾇ ﾞ09O 6ﾒ2 ﾇ03 ﾇ096ﾑ806O09 ﾇ03ｦﾐ ﾞ ﾞｦﾐ6ﾒ2 ﾇ6ｾ4 ﾇ6ｾ4 罔ﾐ ﾞ ﾒ ﾞ05O06ｦﾐ6ｾ409O 6ﾒ2ｦﾐ09 ﾇ6ｾ4 096ﾑ80106ｦﾐ 6ﾒ2 ﾇ03 6ﾑ8036ﾒ2 ﾞ6ｦ1 ﾇ 6ｾ46ﾒ2 ﾇ ｦﾐ6ｾ46ﾒ2 ﾞ 90 days 180 days 100 Prising P&R Reimbursement Publication 200 300 400 500 600 700 800 00 ﾇ 0ｸ709006ｧ9 0007 閨040006 0206006ｧ8 030307 閨040006 02fi0402o0ｹ003, 03000006 o ﾞ070206apple03fi00 03o0ｹ0 02090ｹ0 EFPIA Jean- Francois Dehecq. ﾇ 016ｧ9 02090ｹ0 030003 apple006ｧ9 0ｹ0 000002030702 06 0000 o0602o07o00060207 000009 閨0309 030307 02 06 applefi 02o appleo02 閨03000400. ﾇ 016ｧ9 03o06applefi07 apple03o04000002030702 06 06 08o030002060207 070703o09 0000 02 040ｸ70008 閨03o0702 020ｷ307 0007 06 080003o00 閨070ｷ307 0000030607. O06 04030007006ｧ90ｹ0 03 閨03o0ｸ707 07 閨04o0ｸ707 040209 06070300046ｧ8 02o0ｸ70ｹ0 02 036ｦ0020003000ｹ0 030003 apple006ｧ9000ｹ0, o06 oappleo6ｧ9000ｹ0 03 apple 03 02006ｧ907o0ｸ707 020907 ｨB0ｷ36ｧ8 02o0ｸ70ｹ0 02 06 03 02o0ｸ70ｹ0 0001 0408 036ｧ9ｨBo0ｸ707 02 036ｦ002000309 appleo06fi020902 ｨB0ｷ36ｧ80ｹ0. 縺06 02o 03fi09o 0ｸ702fi 0007 06 08 閨03o0702 06 fi03o 02 06 apple0003060404fi020003o 07 040ｸ700000002 閨04o0ｸ707 04020907 036ｧ86 709 appleo080704000ｷ307 0906 020907 0ｸ7090006o07o0006026ｧ8 apple00036ｧ903 036 709 02 06 0007 appleo 閨04o0702 06 020907 apple0003060402o036ｧ8 apple 070607 appleo0ｸ7 0ｸ706o030002o6ｦ007 o06 020ｸ76 50003076ｧ80400060ｹ0. ﾇ 閨03000ｸ707 006ｧ904070006 fi0206 09 apple03fi046 5 0409 020ｷ307 040300070607 0402 07 陦 08070300-02 apple 030000appleo 6ｧ9ｨB0002 06 applefi 02060ｹ0 02 030ｸ7040200036ｧ80400060ｹ0 04020907 閨090203060409, 0402o07 02 03o03060400fi 0206006ｧ80ｹ0 02 06 020907 0207030ｸ76 709 applefi 020907 02o06070ｷ30706026ｧ8 04080703060409. O06 04030007006ｧ90ｹ0 03 閨03o0ｸ707 02 040ｸ704026ｧ800 02 02o06070ｷ30706026ｧ80ｹ0 040807030604090ｹ0 07 0702 appleo02036ｧ907o0702 06 0402060ｹ0 07070902000ｹ0 02o0ｸ70ｹ0. ﾇ 000706 6ｧ9 09o0307 08 030007020ｷ307 0007 閨040006 00apple0602000ｸ70403006ｧ9. 09 030703030903 09 0007020ｸ7apple0ｷ30406 026ｧ8 0707apple020ｸ70109 02o0ｸ7 apple 03 03036ｧ803o0ｸ7 0000appleo036ｧ9o0ｸ7 appleo 0ｸ70707000ｷ30400 020907 0702 090ｷ3070604020602fi020902 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 02 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 040ｷ3036ｧ90ｹ0 07 apple 03 閨040006 apple0300o070002026ｧ800 02 0402o0ｸ70ｹ0 04030007006ｧ90ｹ0. 05000ｷ3030902060207 o06 04030007006ｧ90ｹ0 04020907 6ﾑ8030307 00apple0ｷ3080003o6ｦ00702 06 06fi0206 02 08070300 02 閨04o0ｸ707 020907 04 000903fi02000309 0206006ｧ8 04020907 6ﾑ80ｸ70306apple09. 6ｾ4020907 apple03070109 fi000ｷ30ｹ0 o06 07 閨000ｹ0 030003 apple006ｧ9000ｹ0 08030707o0ｸ707 04020907 6ﾑ8030307 15 006ｧ807000ｹ0 0309fi020003 0400 0404 閨0409 0000 020907 ﾞ0909036ｧ9 6ｧ8 020907 縺000300 076ｧ9. 6ﾑ8apple6ｧ9 apple03 鑰07 03fi090ｷ3 020ｷ307 apple 03 03036ｧ8030ｷ307 0001 090ｷ3090607 o06 0303030907000ｹ0 040300-07006ｧ90ｹ0 04020003o6ｦ00702 06 02 07 陦 08070300 02 00apple0006 6ｧ8 0906 o03060400 閨07 applefi 0ｸ70207 00 閨040306 02 06 02o 90% 00apple 07000107090002 06 applefi 00000407ｨBo0702000ｹ0 0400 ﾒ03070209-09 閨0309 appleo0ｸ7 閨04o0ｸ707 0ｸ76 70903fi02000309 0206006ｧ8. 6ｾ402o apple0003066 5070303o07 0ｸ702fi 09 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9 0003006ｦ007090ｹ0 apple 03006ｦ00006 07 appleo02 02 04026ｧ8040006 020907 0702 090ｷ3070604020602fi02090207 02090ｹ0. O06 020600 閨0ｹ0 020ｷ307 08 030007020ｷ307 02 03o036ｧ9ｨBo0702 06 0000 6 5070409 0209 04 000903fi02000309 0206006ｧ8 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0, appleo0ｸ7 006ｧ907 06 09 000303090706026ｧ8 046ｧ8000003, 09 6 5o0ｸ70309 0306026ｧ8 02 06 03o0ｸ700 0706026ｧ8 6ｦ00306o. ﾇ 02 02070402 0409 0ｸ7026ｧ8 006ｧ904070006 020907 appleo0ｸ7046ｧ9 00 0203oapple03fi03000400o0ｸ7 o0307-00 02o0ｹ0 0906 020907 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9 04020907 6ﾑ80ｸ70306apple09. O06 040ｸ70402070400060ｹ0 02o0ｸ7 G-10* 02 06 06 06 6ｧ9020003 09 046ｦ00402 0409 VI 6ｧ907o0ｸ707 020603 0207appleo06 0003apple6ｧ9 02 06 00appleo03006ｧ9 07 040ｸ7006 5070303o0ｸ707 040209 090006o0ｸ703-096ｧ9 02 036ｦ0020003o0ｸ7 apple0003066 5070303o0702o0ｹ0 appleo0ｸ7 03 00apple060203 閨6 70006 0402o0ｸ70ｹ0 04030007006ｧ90ｹ0 07 03 閨6 7o0ｸ707 09036ｧ809o03 02o0ｸ70ｹ0 02 03appleo6ｦ00ｹ0 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0. ﾇ 6ｾ46ｦ00402 0409 VI 02o0ｸ7 G10 07 08 閨030006 02 0001 ﾇ 6ｾ46ｦ00402 0409 VI 02o0ｸ7 G10 07 08 閨030006 02 00016ｧ80ｹ0: 00 ﾇ 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 (Commission) 02 06 02 ﾒ03070209 09 閨0309 apple03 鐶pple0006 07 06 0408 036ｧ904o0ｸ707 020907 03046ｧ8 fi0206 09 0300o 06fi020902 020ｷ307 ﾒ03 020607-0900030607 07 030ｸ703006ｧ9ｨBo0ｸ707 02060ｹ0 020600 閨0ｹ0, 08o0307 00fi07o 02 08070300 02 appleo0ｸ7 02 036ｦ0apple02o0702 06 applefi 020907 02o06070ｷ30706026ｧ8 04080703060409. 縺06 08070300 02 appleo0ｸ7 0007 02 036ｦ0apple02o0702 06 applefi 020907 02o06070ｷ30706026ｧ8 04080703060409 6ｧ8 06 026ｧ903000702 06 applefi 06 060ｷ3020602 閨0ｹ0 09o03 閨0ｹ0 apple03 鐶pple0006 07 00apple06-0203 鐶pple0002 06 o 0003006ｦ0030003o0ｹ0 0702 090ｷ307060400fi0ｹ003. ﾇ 6ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ0 0007 閨040006 07 020003 6ｧ9040006 026ｧ9appleo0200 appleo 0ｸ707 000607o0702 0ｹ0 020907 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9. 6ﾑ80707 09 閨03000ｸ707 0906 07 陦 08070300 02 appleo0ｸ7 096ｧ9070002 06 04020907 6ﾑ80ｸ70306apple09 appleo 0ｸ707 000ｷ303006ｧ9 02fi0009 apple0003060404fi020003o 09 6ﾑ80ｸ70306apple09 03 0407040006 0400 fi03 02 00apple6ｧ9apple00 : 05 appleo 0ｸ707 000ｷ303006ｧ9 09 apple 0404fi03090409, o06 o0602o07o000602 閨0ｹ0 03 0402090306fi020902000ｹ0 02 06 02 閨03o0ｹ0 09 00030706026ｧ8 o0602o07o006ｧ9. ﾞapplefi o0409 6ｾ4. 09000307 04/07020306 6ﾑ8apple0604020900080706020607 03000007020ｷ307 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 23

13EFPIA ANNUAL MEETINGS ATHENS 2003 02070300 02 0906 020907 0703030ｷ3applefi020902 "MEDICINES FOR MANKIND" 0307 07 060607 apple030607 02 06 04020907 apple03 0900 020602fi020902 25 0403fi0706 apple030607, 09 07026ｧ903096 76ｧ8 00 0ｹ0 0906 02060ｹ0 06-026ｧ9000ｹ0 020ｷ307 0403000700060607 6ｧ802 07 00070303o07 apple000306o03060400 閨0709. ﾇ applefi08 0409 02090ｹ0 06000307o6ｦ00ｹ0 00apple06-04020900o0706026ｧ80ｹ0 02o0607fi020902 0ｹ0 07 040ｸ707000309 0403006ｧ9 0906 07 07 02 036ｦ06 70006 02o0ｸ70ｹ0 000904 07060400o6ｦ00ｹ0 appleo0ｸ7 00apple09030007ｨBo0ｸ707 0209 6 506o03o096ｧ9 02o0ｸ7 07030306appleo0ｸ7, 020ｷ307 ｨB060ｷ307 02 06 020ｷ307 00060203oo0309 070604000607, 閨040006 040ｸ707020003 閨040006 02 020003000ｸ702 6ｧ9 0403fi0706, 00 閨040ｷ3 apple03o0903 000007020ｷ307 fiapple0ｷ30ｹ0 09 04 0302o09030708090409 02o0ｸ7 09o0706 060600 02o0ｹ0, 04020907 apple 03046ｧ8 0ｸ702o6ｦ0 appleo0ｸ7 o07o0007ｨbo0ｸ70000 090007o0006026ｧ8 00apple 07070402 0409. 6ﾒ2 08070300 02 appleo0ｸ7 020ｸ70203o08fi030904 07 02 020003000ｸ702 6ｧ9 25 0403fi0706 6 5 046ｧ9ｨBo0702 06 04020907 00apple0604026ｧ80009 02090ｹ0 00o0306 026ｧ80ｹ0 6 506o03o096ｧ9 0ｹ0 00 閨040ｷ3 02090ｹ0 oappleo6ｧ9 0ｹ0 o06 00apple0604026ｧ800o07000ｹ0 6 5036ｧ802 07 0203fiappleo0ｸ70ｹ0 07 0600-09006ｧ903o0ｸ707 6ｧ8 07 apple 030000appleo 6ｧ904o0ｸ707 0209 03070409 030ｸ7030006040206020607 apple 03 09fi07020ｷ307 appleo0ｸ7 0000apple03 閨02o0702 06 0402 060708o03 040207 06 02090ｹ0 07fi04o0ｸ7, fiapple0ｷ30ｹ0 o06 6ｧ9 0ｸ703o06 06fi07020ｷ307, o06 0ｸ7appleo o04006ｧ90ｹ0, 6ｧ8 02 閨07ｨB0ｸ700. ﾇ 0ｸ7096ｧ8 02o0ｸ7 21o0ｸ7 060607 apple 03o0ｸ7040607ｨB0006 閨07 0007020003060ｹ0 07 鑰 02oapple6ｧ9o 0000 02060ｹ0 000100036ｧ90100060ｹ0 02090ｹ0 090007o0006026ｧ80ｹ0 6ｧ8 02fi0009 040900 07020602fi020003, 02090ｹ0 apple030ｷ30200o0006026ｧ80ｹ0 (0000 020907 oappleo6ｧ9 apple03o04apple 03o6ｦ00000 07 02 02 07o6ｧ804o0ｸ70000 02 036ｦ0020003 02060ｹ0 03000602o0ｸ703096ｧ9000ｹ0 020ｷ307 apple030ｷ302000ｸ8070607). ﾇ 0303 096ｧ8 0ｸ7026ｧ8 00 0ｹ0 apple03o0408 閨030006 0006 0007020003060ｹ0 02 0607o6ｦ00306 apple03o04 閨0909060409 0906 0403 閨070006000ｹ0 02o0ｸ7 07 apple020ｸ70900 閨07o0ｸ7 6ｧ8 02o0ｸ7 0ｸ7applefi 0707apple020ｸ70109 02fi0400o0ｸ7. 09 030703030903, 000100036ｧ90100060ｹ0 040209 6 506o02000407o03o096ｧ9 o 0909o6ｦ007 0400 08070300 02 appleo0ｸ7 0402o04006ｦ0o0ｸ707 0000 000009 036ｦ002000309 02036ｧ96 50006 0400 026ｦ00306000ｹ0 03000602o0ｸ703096ｧ9000ｹ0 appleo0ｸ7 00apple09030007ｨBo0ｸ707 020907 0001 閨03060109 020ｷ307 07o04090007020ｷ307. 6ﾒ2o6ｦ002o 閨040006 0ｷ30ｹ0 appleo02 閨03000400 0209 090006o0ｸ703096ｧ9 02 06 020ｸ70203o08o036ｧ9 00006 5o036ｧ90ｷ307 0906 0403 閨070006000ｹ0 0009 0702060000020ｷ3apple06ｨBfi000007000ｹ0 00 閨040306 046ｧ8000003. ﾇ 07 陦 0ｸ7026ｧ8 00apple0604026ｧ80009 020ｷ307 0000-6 5o036ｧ90ｷ307 0906 030003 apple000ｸ70206026ｧ8 04036ｧ80409 006ｧ907 06 0007020003060ｹ0 06 08o03000206026ｧ8 applefi 020907 apple 03 o0406 026ｧ8 00 閨040306 046ｧ8000003 04036ｧ80409 020ｷ307 00006 5o036ｧ90ｷ307 0906 apple03o086ｦ003 0109. ﾇ 07 0207030ｸ76 709 02 06 09 0707apple020ｸ70109 07 閨0ｷ307 08 030007020ｷ307 006ｧ907 06 0006 00 020307 02 06 apple00036ｧ9apple03o0209 06 0602 046ｧ9. ﾒ 07o07060207, 06 0302006ｧ9 apple0003060404fi020003o applefi 10 0403fi0706 applefi 0209 04020609006ｧ8 02090ｹ0 07 0207030ｸ76 7090ｹ0 02o0ｸ7 07 鑰0ｸ7 00o036ｧ9o0ｸ7 00 閨040306 020907 020ｸ70203o08o036ｧ9 02o0ｸ7 07 鑰0ｸ7 08 03000702o0ｸ7. ﾇ 06 0602 046ｧ9 apple00030603 006 507070006 0006 0400060307 apple 0307030309030ｷ307 03 0402090306o026ｧ8020ｷ307 apple03o02000600 閨07o0ｸ7 07 06 0408 03060403006ｧ9 fi0206 02o 07 鑰 00fi0306o appleo0ｸ7 07 02 036ｦ00803090200 apple 03 閨040006 00apple 03026ｧ8 040807030006 02 06 appleo020003000400 020602fi020902 閨07 070206 02090ｹ0 0403 閨070006 0ｹ0 appleo0ｸ7 apple03oo036ｧ9ｨb0002 06 07 030003 apple006ｦ00006 000009070309 appleo060206036ｧ9 apple0309030ｸ704000607 040300070607. ﾞ02fi0009 02 06 00000207 applefi 020907 閨090203060409 02o0ｸ7 07 鑰0ｸ7 08 03000702o0ｸ7, 09 閨03000ｸ707 03 040ｸ7070004060403006ｧ9 0906 07 0200020009030606040006 020907 appleo020003000400 020602fi020902 02o0ｸ7 07 鑰0ｸ7 00010003060900 閨07o0ｸ7 08 03000702o0ｸ7 0400 000ｸ7036ｦ0020003o0ｸ70ｹ0 apple0309030ｸ70400o6ｦ00ｹ0 040300070607. ﾇ fi0309 03 0402090306fi020902 0007 閨040006 0ｸ76 70903fi02 02o 02fi0402o0ｹ0, apple0003060404fi020003o applefi 750 0002 02o00006ｦ00306 02 06 appleo0303 閨0ｹ0 08o03 閨0ｹ0 080307070006 02o 1 06040002 02o00006ｦ00306o, 00 閨040306 02o 07 鑰 08070300 02o 07 020003006ｧ9 040209 060703000409 02o0ｸ7 04030007o6ｦ00ｹ0. 24 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

136ﾒ2 00apple0602006ｦ00900 02 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0 apple 03080ｸ7040607ｨB080702 06 040208 000ｸ7036ｦ002000308 02080607fi 0900 020907 000ｸ702 06036ｧ9 02090ｹ0 25090ｹ0 00apple0002006ｧ9o0ｸ7 (1978-2003) applefi 02090ｹ0 06 036ｦ004000ｷ30ｹ0 02090ｹ0 EFPIA (European Federation of Pharmaceutical Industries and Association) apple 03o0ｸ7040607-0403090200 0006 0006 06026ｧ8 閨0203000409 09 oappleo6ｧ9 apple03fi02000602 06 07 02 0106 閨6 70006 0400 fi0309 020907 6ﾑ80ｸ70306apple09 apple03o02000600 閨07o0ｸ7 07 07 006ｧ9010006 02 o08 閨0309 02 06 02060ｹ0 apple03ooapple020602 閨0ｹ0 02090ｹ0 apple030ｷ302oappleo0306 026ｧ80ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0. ﾇ 閨0203000409 0002070300 02 0906 020907 ﾞ0703030ｷ3applefi020902 03 apple03o6 507030006 0209 040900 07020602fi02 0209 040ｸ70700060408o0307 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0 04020907 06 020306026ｧ8 apple03fio o apple 03o0ｸ7040607ｨBo0702 0ｹ0 0006 appleo03036ｧ8 046ｦ00702o0009 07 03o006ｧ8 0402 00apple0602006ｦ00900 02 02090ｹ0 閨03000ｸ707 0ｹ0 0400 apple00036ｧ9appleo0ｸ7 25 030003 apple000ｸ7020602o6ｦ00ｹ0 02o00006ｧ90ｹ0. ﾇ 閨0203000409 07 08 閨030002 06 0402 00apple0602006ｦ00900 02 02o0ｸ7 apple 03000303fi0702o0ｹ0 02 06, 0402060ｹ0 000ｸ702 06036ｧ9000ｹ0 02o0ｸ7 00 閨0303o0702o0ｹ0 0906 07 陦 08070300 02 appleo0ｸ7 03 040ｸ707020003 閨04o0ｸ707 04020907 02fi0009 000009 036ｦ002000309 6 50003026ｧ90ｷ30409 02090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 000ｸ7090000036ｧ9 0ｹ0 02o0ｸ7 07030306appleo0ｸ7. 09 030703030903, 0402 apple03 6ｧ90406 02090ｹ0 EFPIA 03000602o0ｸ70309006ｧ9 09 O0007 020ｷ307 0406000ｸ7030ｸ707020607 0303000ｸ707 0ｹ0 (Research Directors Group ｨC RDG). H RDG 006ｧ907 06 0006 o0007 0ｸ76 70903o6ｦ0 00apple06apple 陦o0ｸ7 0006 06020607 0402 03 閨00 02 閨03000ｸ707 0ｹ0, appleo0ｸ7 00030907ｨBo0702 06 0402060ｹ0 0002 06036ｧ9000ｹ0-00 閨0309 02090ｹ0 EFPIA 02 06 006ｧ907 06 0002006ｧ907 02 04020003 閨0409 appleo0ｸ7 006ｧ907 06 0ｸ7apple006ｦ0030ｸ7-07 0906 020907 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109 020ｷ307 08 0300 02000ｸ70206020607 apple03o0ｸ8fi07020ｷ307 04020907 apple000306o046ｧ8 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0. O 0402oapplefi0ｹ0 02090ｹ0 RDG 006ｧ907 06 07 07 006ｧ9010006 0209 04appleo0ｸ7 06fi020902 02090ｹ0 閨03000ｸ707 0ｹ0 0906 0209 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9 02 06 07 06 0408 036ｧ9040006 fi0206 o06 applefi6 700060ｹ0 02090ｹ0 08 0300 02o6 506o000904 076ｧ9 0ｹ0 03 006 50707o0702 06 0ｸ7applefi6 709 0402060ｹ0 040ｸ7ｨB09026ｧ80400060ｹ0 0906 020907 apple03o 090ｷ3096ｧ8 02090ｹ0 0702 090ｷ3070604020602fi0209-02 0ｹ0 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 0402o07 02o00 陦 02090ｹ0 6 506o0ｸ8 020306026ｧ80ｹ0/08 0300 02000ｸ7-0206026ｧ80ｹ0 0303000ｸ707 0ｹ0. O06 07000004o06 0402fi04o06 02090ｹ0 RDG 閨04o0ｸ707 020003006ｧ9 04020907 apple03060209 040ｸ70707-0702090409 02090ｹ0 o0007 0ｹ0 0402060ｹ0 14 02006 503o0ｸ7 036ｧ9o0ｸ7 2003. 1. 0903o0002o0600 046ｧ9 apple030903o08o0306 02o6ｦ0 0ｸ7030602o6ｦ0/0002apple 06 000ｸ70206020607 080ｸ70303 6ｧ90ｷ307. 6ｾ402fi04o0ｹ0 02o0ｸ7 0ｸ7030602o6ｦ0 0ｸ702o6ｦ0 006ｧ907 06 07 07-006ｧ9010006 0209 040900 046ｧ9 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ707 0ｹ0 & 0707- apple020ｸ701090ｹ0 04020907 6ﾑ80ｸ70306apple09. 05 apple 03o0ｸ70406 0403o6ｦ007 02 07 陦 080703-00 02 appleo0ｸ7 000902036ｧ9030902 07/020ｸ70203o08fi030904 07 04020907 6ﾑ80ｸ70306apple09 02o 2001/2002. 6ﾑ8apple6ｧ904090ｹ0, 03 apple0003060903 08006ｧ9 0000 apple03fi 0203fiappleo 02o 09060ｹ0 ﾞ07 02 036ｦ0apple02o0702 06 02 06 ﾞ07 apple026ｦ00404o0702 06 02 02070300 02. 2. 0903o0002o0600 046ｧ9 "Position Papers" 0906 04036ｧ80409 020ｷ307 0000030607 02090ｹ0 EFPIA/EBE/EVM 04040002060207 0000 ｨB09026ｧ800 02 fiapple0ｷ30ｹ0 09 閨03000ｸ707 0400 apple000603 00 02fiｨB0ｷ3, o06 07 閨000ｹ0 02000407o03o096ｧ9000ｹ0 fiapple0ｷ30ｹ0 02o010602o090007o0006026ｧ8 02 06 o06 000100036ｧ90100060ｹ0 040209 08 0300 02000ｸ70206026ｧ8 閨03000ｸ707 & 0707apple020ｸ70109. 3. 6ﾑ8apple0602o06070ｷ3076ｧ9 0000 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 0906 020907 0702 0303 096ｧ8 applefi6 7000ｷ307 0000 0402oapplefi 020907 0707apple020ｸ70109 0602026ｦ0o0ｸ7 02 閨0702030ｷ307 ﾞ03060402006ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09, 02 03060ｹ0 02 06 0209 04030900 02o fi02090409 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 0906 ｨB09026ｧ800 02 6ﾑ8apple06040209000607 0809006ｧ9 0ｹ0. 0903fi00 03o0ｹ0 02090ｹ0 RDG 006ｧ907 06 o ﾒ 03090909026ｧ80ｹ0 6ﾒ2revor Jones, 縺00070602fi0ｹ0 04/0702090ｹ0 02o0ｸ7 08030002 070602o6ｦ0 6ｾ40ｸ707 閨0400o0ｸ7 02 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0 (ABPI). 6ﾒ2 00apple0602006ｦ00900 02 02o0ｸ7 apple 03000303fi0702o0ｹ0 02 06 o06 02 02 02026ｧ80400060ｹ0 02090ｹ0 00apple0604026ｧ800090ｹ0 appleo0ｸ7 040ｸ707020003o6ｦ00702 06 02 020003000ｸ702 6ｧ9 0403fi0706 閨04o0ｸ707 06040006 0006 0604040ｸ7036ｧ8 0603090409 04020907 0707apple020ｸ70109 0000090703o0ｸ7 03060300o6ｦ0 07 閨0ｷ307 08 030007020ｷ307, apple06o 00010003060900 閨070ｷ307, 02fi04o 0ｷ30ｹ0 apple03o0ｹ0 020907 00010006-6ｧ902000ｸ70409 fi04o 02 06 0ｷ30ｹ0 apple03o0ｹ0 020907 040807030006 02 06 020907 appleo02000300-0400 020602fi020902. ﾇ 0303000ｸ707 02 06 ﾞ0707apple020ｸ70109 03 040ｸ70700046ｧ904o0ｸ707 07 000100036ｧ90404o0702 06, 02 03060ｹ0 07 閨000ｹ0 apple03o02036ｧ80400060ｹ0 000008 076ｧ9ｨBo0702 06, fiapple0ｷ30ｹ0 apple03fi0408 02 02o SARS (04o6 5 03fi o016ｦ0 07 apple07000ｸ704020602fi 046ｦ007 03o00o). ﾇ 08 0300 02000ｸ70206026ｧ8 閨03000ｸ707 0007 apple03fi02000602 06 07 0402 00 026ｧ8040006 00 06, 6ｧ8 fiapple0ｷ30ｹ0 006ｧ9apple00 o Prof. Trevor Jones "we cannot stop now". ﾇ 02 0300 02000ｸ70206026ｧ8 0806o000904 076ｧ9 006ｧ907 06 0402 03000307 apple03o04 07 02o0306-0400 閨0709 04020907 07 0207030ｸ76 709 02 06 060703000409 07 閨0ｷ307 appleo020003000400 0206-02fi0200030ｷ307, 0408 03 閨040200030ｷ307 02 06 0106fiapple0604020ｷ307 08 030007020ｷ307 04020907 0ｸ7apple090300046ｧ9 02090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 000ｸ7090000036ｧ9 0ｹ0 02090ｹ0 0703030ｷ3applefi020902 0ｹ0. ﾞapplefi 080409: ﾞ0602 0200036ｧ90709 09 apple 030ｷ30007 04/07020306 ｦﾐ 02030602086ｦ0 6ﾒ2006ｧ800 02080ｹ0, Janssen-Cilag 02 0300 02000ｸ70206026ｧ8 ﾞ6ﾑ8086ﾑ8 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 25

13EFPIA ANNUAL MEETINGS ATHENS 2003 ﾒ 036ｦ0020003 08070300 02 0906 02 apple 06 0607 6ﾒ2 08070300 02 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409 0007 apple00030603 006 50707o0ｸ707 apple070702 apple030903o08o036ｧ9000ｹ0 04040002060207 0000 020907 0408 036ｧ8 02 06 appleo020003000400 0206026ｧ8 04036ｧ80409 02o0ｸ70ｹ0 0400 apple 06 0607, apple 03 ｯ fi03o appleo0ｸ7 0ｸ70207 070206apple03o040ｷ3apple006ｦ0o0ｸ707 閨07 02o0607fi 75 0002 02o00000ｸ7036ｧ90ｷ307 04020907 6ﾑ8.6ﾑ8. 6ﾒ2o 07030303o appleo0ｸ7 02o03o0ｸ703006ｧ9 040206 0903 08006ｧ9 02o ｨB6ｧ8020900 00 閨040306 02 06 020907 apple03fi0408 0209 apple03fi02 0409 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 00 ﾒ 036ｦ0020003 02070300 02 0906 02 09 06 060703 09 oappleo6ｧ9 0001000207ｨB0006 03020002 閨0ｹ0 apple0603 07 閨0ｹ0 036ｦ00400060ｹ0 apple03o02000600 閨07o0ｸ7 07 6 5000302060ｷ303006ｧ9 09 06 0300040600fi020902 02 0207030309030ｷ307 0906 02 apple 06 0607 08 030007020ｷ307. O06 00076ｧ8030602000ｹ0 04030007006ｧ90ｹ0, apple030607 apple0703o0ｸ707 0207appleo06o 08070300 02o, 00appleo03o6ｦ007 07 006ｧ907 06 046ｧ909o0ｸ703o06 fi0206 0ｸ702fi 閨040006 000300090403006ｧ9 00apple060402 00 閨07 0906 07 0001 0408 03060402006ｧ9 09 040807030006, 09 appleo0200-03000400 020602fi020902 02 06 09 0ｸ76 709036ｧ8 02o0ｸ7 appleo06fi020902. 040ｸ704020ｸ704060ｹ0 02o 6ｧ9 06o 0007 00appleo03006ｧ9 07 0006apple0ｷ303006ｧ9 02 06 0906 fi03 02 08070300 02 appleo0ｸ7 apple 6ｧ90307o0ｸ707 02 apple 06 0607. 6ﾑ8020206000702 06 fi0206 apple00036ｧ9appleo0ｸ7 02o 50% 020ｷ307 08 030007020ｷ307 appleo0ｸ7 040309040600oappleo06o6ｦ00702 06 0400 apple 06 0607, 020ｸ7036ｧ90ｷ30ｹ0 0ｸ70207 appleo0ｸ7 040309040600oappleo06o6ｦ00702 06 0400 0006 0602 閨0ｹ0 apple0003060402070400060ｹ0, fiapple0ｷ30ｹ0 0400 00o0707 000ｹ0 000702 0206026ｧ80ｹ0 apple 03 02o03o6ｦ0030904090ｹ0, 0400 0700o090707 6ｧ8 0400 apple03fi0ｷ303 000ｷ30307, 0007 閨040006 00000300020903006ｧ9 02 06 appleo 00060402006ｧ9 02 020703030903o 0906 04036ｧ80409 0400 000ｷ30307. 6ﾒ2 08070300 02 appleo0ｸ7 020ｸ70203o08o03o6ｦ007 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409 0007 apple00030603 006 50707o0ｸ707 apple070702 apple030903o08o036ｧ9000ｹ0 04040002060207 0000 020907 0408 036ｧ8 02 06 appleo020003000400 0206026ｧ8 04036ｧ80409 02o0ｸ70ｹ0 0400 apple 06 0607. ﾞ0ｸ702fi 閨040006 0ｷ30ｹ0 appleo02 閨03000400 0209 04o036ｧ809090409 08 0300 02000ｸ70206020607 apple03o0ｸ8fi07020ｷ307 appleo0ｸ7 0007 閨04o0ｸ707 020907 apple 0602o6ｦ000000709 閨090203060409 0906 04036ｧ80409 0400 apple 06 0607, 0000 apple0603 0707 0ｸ704000007006ｧ90ｹ0 00apple06apple02060400060ｹ0. ﾇ 0ｸ7080604020700000709 02 02070402 0409: 6ｾ4020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 03070ｷ30409, 09 0903060206 026ｧ8 o0007 applefi 0 閨0ｷ30ｹ0 16 00020607 070206apple03o040ｷ3apple006ｦ00006 apple00036ｧ9 02 75 0002 02o00006ｦ00306. 09 03 ｯ fi03o appleo0ｸ7 0ｸ702fi0ｹ0 o 03060300fi0ｹ0 006ｧ907 06 0007020ｸ7apple0ｷ30406 02fi0ｹ0, 09 apple030006o6 709086ｧ9 020ｷ307 08 030007020ｷ307 02fi00 000100036ｧ904040002 06 02 06 0402o04006ｦ00006 04036ｧ80409 applefi 00076ｧ8030602o0ｸ70ｹ0 o06 oappleo6ｧ9o06 03060300o6ｦ007 apple00036ｧ9appleo0ｸ7 300 0002 02o00006ｦ00306. 6ﾒ2o ｨB6ｧ8020900 096ｧ9070002 06 02fi00 apple06o 046ｦ007030002o applefi 02o 090009o07fi0ｹ0 fi0206 09 0903060206 026ｧ8 o0007 020ｷ307 0-16 00020607 00appleo03006ｧ9 07 06 040ｷ303060402006ｧ9 apple0003 0602 閨030ｷ3 0400 040ｸ709020002030600 閨07000ｹ0 0ｸ7appleoo0007 000ｹ0 appleo0ｸ7 apple00030603 00-6 50707o0ｸ707 applefi 0700o090707 00 閨040306 00086ｧ86 5o0ｸ70ｹ0, 0000 06 08o030002060207 04 03 02020903060402060207 0707apple020ｸ701090ｹ0 02 06 040ｸ700apple00030608o03070ｹ0. 縺06 026ｧ9 09 08 0300 02o6 506o000904 076ｧ9 6ｧ802 07 060402 020206026ｧ8; O06 03fi09o06 0906 02o0ｸ70ｹ0 oappleo6ｧ9o0ｸ70ｹ0 09 08 0300 02o6 506o000904 076ｧ9 0ｸ7apple6ｧ8030100 0402o apple 03000303fi07 060402 02020602 閨0ｹ0 07 0207070006 02060ｹ0 apple 03 6ｧ9020902000ｹ0 o020600 閨0ｹ0 02 06 07 apple03o04 0300fi040006 02 apple03o0ｸ8fi0702 02o0ｸ70ｹ0 0402060ｹ0 07070902000ｹ0 020ｷ307 apple 06 060607 006ｧ907 06 appleo0303 apple03o6ｧ9. ﾇ apple 0602o6ｦ000000709 apple03o04apple07030006 04040002060207 0000 0209 030003 apple006ｧ9 apple 06 06020607 0403000700060607 006ｧ907 06 0001 06030002060207 000009070309, 00apple0006 6ｧ8 apple00030603 006 507070006 00 0203oapple03fi0300-040009 apple 03 02o03o6ｦ003090409 020ｷ307 0303090300apple06 030704000ｷ307 000002 016ｦ0 020ｷ307 08 030007020ｷ307 02 06 02o07 000702oapple060400fi apple 03000700030900060607. O06 020306070602 閨0ｹ0 000003 閨02000ｹ0 apple 0602o6ｦ007 6ｦ00402o03o 040400 06 0400fi 02 06 00appleo03006ｧ9 07 閨04o0ｸ707 appleo036ｦ0 0ｸ76 70903fi 02fi0402o0ｹ0. 縺06 ｯ 0ｸ702fi 02 閨04o applefi 020907 0001 閨03060109 02o0ｸ7 08 03000702o0ｸ7 00appleo03006ｧ9 07 000907 02 036ｦ0- apple02o0ｸ707 02o 6ｦ06 7o0ｹ0 02090ｹ0 apple 0602o6ｦ0000007090ｹ0 00apple 閨07 0ｸ704090ｹ0. 6ﾑ8apple6ｧ904090ｹ0 0403000607ｨB0002 06 040400 06 0400fi0ｹ0 0006 06020607 0402000ｸ7 040007020ｷ307 0906 00060203o6ｦ00ｹ0 04030007006ｧ90ｹ0 fiapple0ｷ30ｹ0 apple.04. 0402000ｸ7070400 02 0400 0ｸ709036ｧ8 00o03086ｧ8 6ｧ8 0400 00o03086ｧ8 04apple03 閨06. 0903o0909o6ｦ0000007000ｹ0 030ｸ703000604020602 閨0ｹ0 apple 0300006 5070400060ｹ0 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8-026ｧ8 03070ｷ30409: 6ﾒ2o 1997, 06o0309 070603090200 060703o09o0ｹ0 040203o09090ｸ7-036ｧ80ｹ0 0203 apple 險B090ｹ0 applefi 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 04040002060207 0000 02o ｨB6ｧ8020900. 0307 applefi 02 040ｸ700apple0003070400 02 6ｧ802 07 02 06 09 0707-090209 07 00070604040ｸ703006ｧ9 09 07o00o0300046ｧ9, 02 06 apple06o 040ｸ709020002030600 閨07 07 090006o0ｸ703090903006ｧ9 0207appleo06o 046ｦ004020900 0206076ｧ802030ｷ307 apple03o0ｹ0 0ｸ7026ｧ8 020907 02 02006ｦ0030ｸ7070409. 6ﾒ2o 1998, 09 6ﾑ8apple060203oapple6ｧ8 0ｸ7appleo04026ｧ803060100 020907 0707-090209 0906 060003076ｧ8 060703o09o 04040002060207 0000 0209 060001 090ｷ3096ｧ8 o0206-000607 0400 apple 06 0607 02 06 02o07 ｦﾐo6ｦ00306o 02o0ｸ7 2000 0ｸ706o0300026ｧ803090200 040400-0206026ｧ8 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 O 09096ｧ9. ﾇ O 09096ｧ9 2001/20/EC 04040002060207 0000 02060ｹ0 O0303 閨0ｹ0 ﾒ0306070602 閨0ｹ0 0903 02020602 閨0ｹ0 (Good Clinical Practices: GCP) 03 006 507070006 0ｸ7applefi6 709 0207appleo06000ｹ0 0006 0602 閨0ｹ0 0709040ｸ7046ｧ9000ｹ0 04040002060207 0000 020907 000202 閨03000409 0203060706020607 o0206000607 0400 apple 06 0607. O06 02 07o07060400o6ｧ9 appleo0ｸ7 08o03o6ｦ007 o0308 0707 08 0300 02000ｸ702060207 apple03o0ｸ8fi0702 (Orphan medicinal products): 08apple070304o0ｸ707 o00o06fi020902000ｹ0 000002 016ｦ0 02090ｹ0 閨030300066 7090ｹ0 閨03000ｸ707 0ｹ0 0906 08 0300-02000ｸ702060207 apple03o0ｸ8fi0702 appleo0ｸ7 apple03oo036ｧ9ｨbo0702 06 0906 apple 06 0607 02 06 08 03-00 02000ｸ702060207 apple03o0ｸ8fi0702 0906 04apple070706000ｹ0 0403 閨070006000ｹ0 (Orphan medicinal products). O06 o00o06fi020902000ｹ0 0ｸ702 閨0ｹ0 o 6ｧ8090904 07 020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 07 apple03o02006ｧ9070006 02o07 ﾒ 07o07060400fi 0404000206-0207 0000 02 o0308 0707 08 0300 02000ｸ702060207 apple03o0ｸ8fi0702, o oappleo6ｧ9o0ｹ0 0ｸ706o0300026ｧ803090200 02o 1999. 0903o08 07060ｹ0 0400 0ｸ702fi07 02o07 ﾒ 07o0706-0400fi 0ｸ7apple070304o0ｸ707 0402o0604006ｧ9 appleo0ｸ7 03 00appleo03o6ｦ004 07 07 040309-040600oappleo060903o6ｦ007 0ｷ30ｹ0 00o0702 閨03o 0906 00000303o07020602 閨0ｹ0 0007 閨03090006000ｹ0. 04060003076ｧ8 apple 03 006ｧ90900 02 : 6ｾ402060ｹ0 ﾇ09 ﾞ, 6ｦ0o 040ｸ700apple0309030ｷ300 02060207 000002 016ｦ0 02o0ｸ70ｹ0, 07o00o030002060207 07030303 0ｸ706o0300026ｧ8030902 07 apple03o020006-26 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

1300 閨07o0ｸ7 07 000703 03030ｸ70703o6ｦ007 o06 020306070602 閨0ｹ0 o020600 閨0ｹ0 0400 apple 06 0607 02o 1997 02 06 02o 1998 07026ｧ90402o0604. O 0009 06 06 02030602fi0ｹ0 ﾒ 07fi07 0ｹ003 00apple060203 鐶pple0006 0402o FDA (Food and Drug Administration) 07 apple 0602006ｧ9 applefi 0002 0603006ｧ9000ｹ0 07 0600010709o0ｸ707 02 閨02o06o0ｸ7 006ｧ9 o0ｸ70ｹ0 閨03000ｸ7-07000ｹ0 02 06/ 6ｧ8 07 07 apple026ｦ00404o0ｸ707 08070300 02 0400 00o03086ｧ8 apple03fi- 0408o0309 0906 apple 06 06 020306026ｧ8 04036ｧ80409 02fi04o 0906 07 陦, fi04o 02 06 0906 6ｧ8 09 020ｸ70203o08o03o6ｦ00702 08070300 02, 0400 apple000306apple02060400060ｹ0 appleo0ｸ7 0ｸ70207 00appleo03o6ｦ007 07 040309040600oappleo060903o6ｦ007 0400 0602 07fi 03060300fi apple 06 060607. O fi03o0ｹ0 appleo0ｸ7 apple03o6 503 鐶pple0006 020907 00apple 06 06 020306026ｧ8 appleo02030006040206026ｧ8 04036ｧ8040903 6ｧ9070006 026ｧ907090203 appleo0ｸ7 apple00030603 006 50707o0ｸ707 6 00apple06apple03 鑰07 006ｧ8-07000ｹ0 apple03o0402 046ｧ9 0ｹ0 02090ｹ0 000ｸ703000406020004076ｧ9 0ｹ0 0402060ｹ0 0002 0603006ｧ9000ｹ0 appleo0ｸ7 0600-07000309o6ｦ007 閨03000ｸ707000ｹ0 0400 apple 06 0607, 0ｸ7applefi 02o07 fi03o fi0206 o06 閨03000ｸ707000ｹ0 0ｸ702 閨0ｹ0 040ｸ7006 5 6ｧ9ｨBo0ｸ707 0000 02 020306026ｧ80306 02o0ｸ7 FDA, fiapple0ｷ30ｹ0 0ｸ702 閨0ｹ0 06 00o03080607o0702 06 6 507040006 020ｷ307 07 09020607 02090ｹ0 0900fi0406 0ｹ0 0ｸ709006ｧ9 0ｹ0. 6ﾑ8apple06apple03fi04030002, o06 07o00o0300020602 閨0ｹ0 030ｸ703006ｧ90400060ｹ0 00apple 閨6 5 03 07 0209 09-0006o0ｸ703096ｧ9 applefi 02o FDA 0006 0ｹ0 00apple 06 06 020306026ｧ80ｹ0 036ｧ90402 0ｹ003, 0903 6ｧ8 0006 0ｹ0 036ｧ90402 0ｹ0 08 030007020ｷ307, 0906 02 oappleo6ｧ9 apple0003 0602 閨030ｷ3 apple 06 06 020306-026ｧ8 apple030903o08fi03090409 03 6ｧ802 07 04036ｧ804060009. 0903fi0408 02 02o ﾒo090203 閨04o 07 03000603090400 02o07 fi03o 02090ｹ0 00apple 06 06 020306026ｧ80ｹ0 appleo02030006040206026ｧ80ｹ0 04036ｧ804090ｹ003. 6ﾑ801 06026ｧ9 0ｹ0 02090ｹ0 00apple06020ｸ7046ｧ9 0ｹ0 02o0ｸ7 040209 090006o0ｸ703096ｧ9 07 閨0ｷ307 apple03o0903 000007020ｷ307 08 0300 02000ｸ70206026ｧ80ｹ0 閨03000ｸ7-07 0ｹ0 0000 0402oapplefi 0209 030003 apple006ｧ9 06 08o03000206020607 0903060206 020607 o0007-0ｷ307 ｨC 0000 21 000002o07o00 046ｧ9000ｹ0 apple03o0ｸ8fi07020ｷ307 02 06 apple0003060404fi020003000ｹ0 applefi 400 000707030100060ｹ0 0003000ｸ7070607 0400 3 0403fi0706 ｨC 07 07000603090200 0003 0803060ｹ0 06 08o03oappleo060900 閨0709. ﾇ apple 06 06 020306026ｧ8 036ｧ90402 03000ｷ3036ｧ8-03090200 0700apple06020ｸ7046ｧ80ｹ0 02 06 000902 02 03006ｧ90803090200. 6ｾ40209 03 閨0409 02090ｹ0 0300-04apple6ｧ90402090200 閨07 02o07 6ｦ00306 080600030ｷ300 閨07o appleo020300060402060207 04020907 閨03000ｸ707 08 0300 02000ｸ70206020607 apple03o0ｸ8fi07020ｷ307, 000202fi0ｹ0 06 0602 046ｧ9 0ｹ0 000ｸ703000406020004076ｧ9 0ｹ0, 0906 04036ｧ80409 0400 apple 06 0607. O 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi0ｹ0 o036ｧ9ｨbo0702 0ｹ0: 6ﾒ2o 040002 閨006 50306o 02o0ｸ7 2000, 02o 6ﾑ80ｸ7030ｷ3apple 0ｸ802fi 6ｾ40ｸ7006 5o6ｦ00306o 0809006ｧ9 0ｹ0 ｨB6ｧ802090400 applefi 020907 6ﾑ8apple060203oapple6ｧ8 07 apple07030006 040ｸ709020002030600 閨07 00 閨0203 apple03o02000600 閨07o0ｸ7 07 030ｸ703006ｧ9040006 020907 02 02070402 0409 00 閨04 04020907 03070ｷ30409. 6ｾ400 0006 apple03060209 apple03fi02-0409, 09 6ﾑ8apple060203oapple6ｧ8 02 02 090607fi02 07 0000 020907 閨030300066 709 02 0207030309030ｷ307 08 0300 02000ｸ70206020607 0402000ｸ7 040007020ｷ307 0906 apple 06 0607. ﾇ apple03fi02 0409, 0000 026ｧ90203o 00 ﾒ 036ｦ0020003 02070300 02 0906 02 09 06 060703 appleo0ｸ7 020ｸ70203o08fi- 03090400 02o 02006 503o0ｸ7070306o 02o0ｸ7 2002, 6ｧ802 07 02o appleo02 閨03000400 0006 0ｹ0 040ｸ7070707020904090ｹ0 020ｷ307 0203 020607 ｨC 0000030607 09 oappleo6ｧ9 apple03 0900 02oappleo066ｧ8-03090200 0402o apple03 6ｧ90406o 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 02 030007020ｷ307 02o 03o 閨006 50306o 02o0ｸ7 2001. ﾇ apple03fi02 0409 0001000207ｨB0006 03020002 閨0ｹ0 apple0603 07 閨0ｹ0 036ｦ00400060ｹ0 0906 020907 apple 03o046ｧ8 0206076ｧ802030ｷ307 0000 0209 00o03086ｧ8 02090ｹ0 apple03o0402 046ｧ9 0ｹ0 apple07000ｸ700 0206026ｧ80ｹ0 06 06o020209046ｧ9 0ｹ0 02 06 apple03o02006ｧ9070006 0209 090006o0ｸ703096ｧ9 0006 0ｹ0 00010006 0602000ｸ700 閨07090ｹ0 o0007 0ｹ0, 02 03060ｹ0 02 06 0209 090006o0ｸ703096ｧ9 0007fi0ｹ0 0602026ｦ0o0ｸ7 0203060706020607 apple 06 060702030ｷ307, o06 oappleo6ｧ9o06 03 閨04o0ｸ707 040ｸ709020002030600 閨0709 0602 07fi020902 060001 090ｷ3096ｧ80ｹ0 o0206000607 0400 apple 06 0607. 6ﾑ8apple06apple03 鑰07, 036ｧ909o0702 06 ｨB09026ｧ800 02 apple030903o08fi030904090ｹ0 02 06 06 0807070006 0ｹ0, 02 03060ｹ0 02 06 09 0707090209 07 06 0408 03060402006ｧ9 閨07 0ｹ0 0ｸ704020903fi0ｹ0 0206 0602 0ｹ0 00o0702o03o096ｧ9 0ｹ0, fiapple0ｷ30ｹ0 apple0003060903070800-02 06 04020907 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 O 09096ｧ9 04040002060207 0000 02060ｹ0 O0303 閨0ｹ0 ﾒ03060706-02 閨0ｹ0 0903 02020602 閨0ｹ0 fi02 07 096ｧ907o0702 06 o020600 閨0ｹ0 0400 apple 06 0607. ﾞapplefi 02o07 ｦﾐo6ｦ00706o 02o0ｸ7 2002, 09 6ﾑ8apple060203oapple6ｧ8 閨040006 03076 50006 apple00036ｧ9 02 60 0404fi0306 04040002060207 0000 0209 040ｸ7006 5o0ｸ703000ｸ70206026ｧ8 02090ｹ0 apple03fi02 0409. 0003o06 fi04o06 apple0707020904 07 07 09070ｷ3036ｧ9ｨBo0ｸ707 020907 0707090209 07 03090803o6ｦ007 040ｸ709020002030600 閨07 000300090202060207 00 閨0203 0000 0402oapplefi 07 6 5000302060ｷ303006ｧ9 09 06 0300040600fi020902 02 0207030309030ｷ307 08 030007020ｷ307 0906 apple 06 0607. 6ｾ40209 000009070309 02o0ｸ70ｹ0 apple030006o6 709086ｧ9, 07 09070ｷ3036ｧ9ｨBo0ｸ707 02o07 00apple006ｧ909o0702 04 03 02026ｧ803 02o0ｸ7 03 閨00 02o0ｹ0 02 06 020907 0707090209 0906 060703000409 040900-070206020607 00 閨040ｷ307 02 06 02o07 0ｸ7036ｧ90ｷ307 apple03o0ｹ0 0ｸ702fi 02o 0402oapplefi. ﾞapplefi 080409 02000600 閨07080ｸ7 09. 09 03020002070209 Public Relations Officer (Roche) 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 27

13EFPIA ANNUAL MEETINGS ATHENS 2003 09 06 06 0203060207 08070300 02 O06 03 閨0400060ｹ0 02090ｹ0 EFPIA 00apple6ｧ9 02o0ｸ7 03 閨00 02o0ｹ0 006ｧ907 06: ｦﾐ02 07oappleo6ｧ9090409 020ｷ307 0006 06020607 07 09020607 0ｸ709006ｧ9 0ｹ0 02o0ｸ7 0007fi0ｹ0 apple 閨00apple02o0ｸ7 02o0ｸ7 apple0309030ｸ70400o6ｦ0 02090ｹ0 6ﾑ86ﾑ8 ﾇ 08 0300 02o6 506o000904 076ｧ9 0003006ｦ007090ｹ0 040ｸ7006 507030006 000700030907 040209 6 50003026ｧ90ｷ30409 02090ｹ0 0ｸ709006ｧ9 0ｹ0 02 06 02090ｹ0 000ｸ7090000036ｧ9 0ｹ0 020ｷ307 apple 06 060607. 01070309 0400 07 陦 08070300 02 02 06 030003 apple006ｧ9000ｹ0, 閨04o0ｸ707 00apple0602000ｸ70403006ｧ9 apple03fio o06 02090ｹ0 06 020306026ｧ80ｹ0 0400 appleo0303o6ｦ00ｹ0 02o00006ｧ90ｹ0 02090ｹ0 apple 06 06 020306026ｧ80ｹ0, fiapple0ｷ30ｹ0 006ｧ907 06 09 0600 02o03o096ｧ9, 09 o0902o03o096ｧ9, 09 000002 00fi0404000ｸ70409 02 03 06070ｹ0 6ｧ8 070008030607, o06 00006 5o0306 0400o6ｧ9. 6ｾ40900 07020602 閨0ｹ0 apple03fio o06 閨04o0ｸ707 00apple6ｧ904090ｹ0 096ｧ9070006 0906 020907 030003 apple006ｧ9 02o0ｸ7 07040300 02o0ｹ0, 020ｷ307 03o06000ｷ3 0607 07fi040ｷ307, 020ｷ307 07 apple07000ｸ7040206020607 apple03o6 503090007020ｷ307 020ｷ307 0700o09070607, 02o0ｸ7 AIDS, 02o0ｸ7 06 6 56ｧ80209, 020ｷ307 07000ｸ703o6 70ｸ704o03o0906020607 06 02 03 040607, 02090ｹ0 020ｸ7040206026ｧ80ｹ0 6ｧ9070ｷ304090ｹ0 6ｧ8 0906 020907 07 02o6ｦ008060409 02o0ｸ7 applefi07o0ｸ7. 030402fi04o, appleo030307 apple03 鐶pple0006 02fi0009 07 096ｧ907o0ｸ707 0906 07 06 0408 03060403006ｧ9 fi0206 02 apple 06 0607 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 03 00apple0ｷ30800030903o6ｦ007 applefi 02 07 陦 08070300 02. 0400 o00 閨07o0ｸ7 fi0206 02 apple 06 0607 0007 006ｧ907 06 0000060203o6ｧ9 00076ｧ8030602000ｹ003, apple03 鐶pple0006 07 060001 0403o6ｦ007 0006 0602 閨0ｹ0 000003 閨02000ｹ0 0906 07 0001 0408 03060403006ｧ9 fi0206 02 08070300 02 appleo0ｸ7 040ｸ70702 09o0903 08o6ｦ00702 06 006ｧ907 06 02 020703030903 0906 apple 06 0607 02 06 0702 appleo02036ｧ907o0702 06 0402060ｹ0 07070902000ｹ0 02o0ｸ70ｹ0. 縺06 apple 0307 00060900, 閨07 08070300 02o appleo0ｸ7 apple03oo036ｧ9ｨb0002 06 0906 apple 06 0607 apple03 鐶pple0006 07 閨040006 02 02070303090309 o04o03o096ｧ9 02 06 00o03086ｧ8 apple03o02000600 閨07o0ｸ7 07 04o0309090903006ｧ9 0000 040807030006 02 06 000ｸ702o036ｧ9. 030402fi04o, 04020907 08 0300 02000ｸ70206026ｧ8 閨03000ｸ707 026ｧ903000702 06 040ｸ709020002030600 閨07 00030ｷ3026ｧ800 02, 000002 016ｦ0 020ｷ307 oappleo6ｧ90ｷ307 006ｧ907 06 o 0403fi07o0ｹ0 02090ｹ0 0707apple020ｸ701090ｹ0 020ｷ307 apple 06 06 020306020607 08 030007020ｷ307, 09 08 0300 02o0200040706026ｧ8 00o03086ｧ8 appleo0ｸ7 006ｧ907 06 02 020703-03090309 0906 02 apple 06 0607, 09 0ｸ70402o036ｧ9 040209 060001 090ｷ3096ｧ8 00000300020607 08 0300 02o020607090206026ｧ80ｹ0, 09 060001 090ｷ3096ｧ8 00000300020607 appleo020003000400 020602fi020902 0ｹ0 02 06 09 0707090209 0906 020907 0003 04060402oappleo6ｧ9090409 02o0ｸ7 020607 6ｦ007o0ｸ7 02 06 02090ｹ0 apple03fi02030904090ｹ0 0ｸ70408o036ｧ9 0ｹ0 0402 apple 06 0607. 0307 00apple06apple03 鑰07 apple03fi6 5030900 006ｧ907 06 09 06 06 06020003fi020902 020ｷ307 o0007 0ｷ307 09030602060607 020ｷ307 apple 06 060607 ( applefi 02 0700o090707 0402o0ｸ70ｹ0 00086ｧ86 5o0ｸ70ｹ0) 02 03060ｹ0 02 06 o06 0ｸ704020903 閨0ｹ0 00o0702o03o090602 閨0ｹ0 apple 06026ｧ80400060ｹ0 appleo0ｸ7 06 鐶ppleo0ｸ707 02060ｹ0 020306070602 閨0ｹ0 000003 閨02000ｹ0. ﾇ 0002 0603006ｧ9 0003006ｦ007090ｹ0 07 03 006 507070006 000009 036ｦ0020003o 036ｧ90402o 02 0207 020907 0707- apple020ｸ70109 08 030007020ｷ307 0906 apple 06 0607. O06 03 0402090306fi020902000ｹ0 0303000ｸ707 0ｹ0 & ﾞ0707apple020ｸ701090ｹ0 006ｧ907 06 0001 06030002060207 040900 07020602 閨0ｹ0, 02 03060ｹ0 0ｸ7apple0703040006 0709040ｸ7046ｧ9 04040002060207 0000 0209 04036ｧ80409 08 030007020ｷ307 0400 apple 06 0607, 000202fi0ｹ0 020ｷ307 0009020002030600 閨070ｷ307 0007 006ｧ901000ｷ307 appleo0ｸ7 07 08 閨03o0702 06 0402o 026ｦ00303o0ｸ7 O 0909060607 01036ｧ804000ｷ30ｹ0. O06 ﾞ0300fi 06000ｹ0 ﾞ0304 閨0ｹ0, 09 00apple0604020900o0706026ｧ8 02o0607fi020902, o06 00apple 0909000300 026ｧ9000ｹ0 02090ｹ0 0ｸ709006ｧ9 0ｹ0, o06 04030007006ｧ90ｹ0, o06 09o07006ｧ90ｹ0 02 03060ｹ0 02 06 o06 08 0300 02000ｸ7020602 閨0ｹ0 00apple06040006036ｧ80400060ｹ0 0003006ｦ007090ｹ0, 040ｸ700080ｷ307o6ｦ007 fi0206 apple 0602006ｧ902 06 00apple000609fi07020ｷ30ｹ0 07 03090803o6ｦ007 00 閨0203 06040200 06 0408 03060403o6ｦ007 o06 02 036ｦ0020003000ｹ0 030003 apple006ｧ9000ｹ0 0906 apple 06 0607. ﾞapplefi030ｸ70209 0707090209: 03 0ｸ7appleo04020903060403006ｧ9 02 06 07 000703 03030ｸ70703006ｧ9 0000 026ｧ907090203 09 0707apple020ｸ70109 0006 06020607 apple 06 06 020306020607 08 030007020ｷ307 ﾇ 0707090209 07 000703 03030ｸ70703006ｧ9 09 閨03000ｸ707 0906 apple 06 06 0203060207 08070300 02 02o076ｧ90403090200 02 06 apple070306 02o07 090706o 02o0ｸ7 2002, 0402 apple03 6ｧ90406 02090ｹ0 O0007 0ｹ0 086 70903o6ｦ0 6ﾑ8apple06apple 陦o0ｸ7 0906 020907 ﾒ 0607o02o006ｧ9 02 06 02 08070300 02 G-10, 09 oappleo6ｧ9 陦0ｷ30400 閨0008 0409 04020907 0707090209 09 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ8 6ﾑ8apple060203oapple6ｧ8 02 06 02 ﾒ03070209 09 閨0309 07 00030004apple6ｧ904o0ｸ707 0006 appleo020003000400 0206026ｧ8 appleo03060206026ｧ8 0206076ｧ802030ｷ307 0906 020907 閨03000ｸ707, 020907 0707apple020ｸ70109 02 06 020ｸ70203o08o036ｧ9 o0308 070607 02 06 apple 06 06 020306020607 08 030007020ｷ30703. 0900 020907 07 02o6ｧ9070ｷ30409 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 02o07 02006 503o0ｸ7070306o 02o0ｸ7 2002, 07 apple02000306030902 07 o06 0003apple6ｧ9 000ｹ0 0402 0007 06 080003fi000007 00 閨0309. 030402fi04o, 09 08 0300 02o6 506o000904 076ｧ9 0003006ｦ007090ｹ0 04020907 6ﾑ80ｸ70306apple09 0001 02o03o0ｸ703006ｧ9 07 apple00030600 閨070006 040ｸ709020002030600 閨07, 04 086ｧ8 00 閨0203 appleo0ｸ7 03 apple 03 閨04o0ｸ707 020907 apple 03 6ｧ902090209 0ｸ7appleo04026ｧ8-03060109 02 06 026ｧ907090203 0906 0303000ｸ707 & ﾞ0707apple020ｸ70109 apple 06 06 020306020607 08070300 020ｷ307 04020907 ﾒo0607fi020902. 6ﾑ86ｧ907 06 02 0603fi0ｹ0 07 06 0408 03060403006ｧ9 09 040900 070206026ｧ8 02 06 0ｸ7010900 閨0709 040ｸ7006 5o036ｧ8 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 0402o apple 0902fi040006o 096ｧ90907000403 06 06040200 02 apple 06 0607 07 閨04o0ｸ707 040209 06070300046ｧ8 02o0ｸ70ｹ0 02 036ｦ0020003 08070300 02. 28 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13006ﾒ2 02 06070802fi00 08070300 02 00apple0803086ｦ007 07 6 5000302060604080ｸ707 040900 0702060207 020907 06 02030808 0300 02000ｸ70206026ｧ8 apple00036ｧ903 036 709 0402060ｹ0 0ｸ7applefi 閨0702 0109 040603000ｹ003, 0208076ｧ9ｨB0006 09 6ﾑ8FPIA ﾒ 0207 0209 060703020006 02090ｹ0 縺000706026ｧ80ｹ0 6ｾ40ｸ707 閨03000ｸ704090ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8-026ｧ80ｹ0 O00o04appleo07 6ｧ9 0ｹ0 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 02 06 6ｾ40ｸ707 閨04000ｷ307 (EFPIA) appleo0ｸ7 apple03 0900 02oappleo066ｧ803090200 04020907 ﾞ036ｧ807 0402060ｹ0 26-28 09 6ｧ9o0ｸ7 2003, 06o0309 070603090200 workshop 0000 03 閨00 000406006ｦ0030ｸ7070409 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0: 09 03o046ｧ8 08apple09030004060607 0809006ｧ9 0ｹ0 04020907 6ﾑ80ｸ70306apple09 02o 201003. 6ｾ402o workshop 040ｸ700000002006ｧ904 07 apple0003060404fi020003o06 applefi 180 046ｦ00700 03o06, 0300fi 06o06 0906 02o 040400 06 0400fi appleo03060206026ｧ80ｹ0 02090ｹ0 0ｸ709006ｧ9 0ｹ0 020ｷ307 0ｸ7applefi 閨0702 0109 040ｷ3030607 02 03060ｹ0 02 06 070602 02o06 0002apple03fi040ｷ3appleo06 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0. 09 0307 02o 090009o07fi0ｹ0 fi0206 09 0406006ｦ0030ｸ7070409 02090ｹ0 6ﾑ8.6ﾑ8. 07 00 閨070002 06 07 apple03 0900 02oappleo060903006ｧ9 046ｦ00702o00 - 閨02 040603000ｹ0 03 000702 0403o6ｦ007 020907 109 09 0ｹ1o0ｸ7 2004 ｨC o Brian Ager, 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 02090ｹ0 EFPIA, 0ｸ7appleo0903070000060400 fi0206 o06 0ｸ7applefi 閨0702 0109 040603000ｹ0 0702060000020ｷ3apple6ｧ9ｨBo0ｸ707 02fi0009 appleo036ｦ0 0000090703 apple03o6 5036ｧ800 02 04020907 apple 03o046ｧ8 06 0203o08 0300 02000ｸ70206026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0 02 06 fi0206 02 apple 0602o6ｦ00000-07 00standards03 0007 閨04o0ｸ707 appleo020003 閨040006 00 閨03o0ｹ0 020ｷ307 06 apple03 0900 02006ｦ004000ｷ307 02090ｹ0 閨0702 01090ｹ0, 06fi0206 o06 040ｸ7ｨB09026ｧ80400060ｹ0 閨04o0ｸ707 00apple0602000702030ｷ303006ｧ9 00fi07o07 04020907 0602 07fi020902 020ｷ307 0ｸ7appleo6 76ｧ8-08060ｷ307 040ｷ3030607 07 0008 0300fi04o0ｸ707 02o 02o0607o020602fi 020002020900 閨07o. 6ｾ402o workshop 09 040ｸ7ｨB6ｧ802090409 00apple0602000702030603090200 0402 ｨB09026ｧ800-02, appleo0ｸ7 閨04o0ｸ707 000009 036ｦ002000309 040900 046ｧ9 0906 02o0ｸ70ｹ0 appleo036ｧ902000ｹ0 020ｷ307 07 閨0ｷ307 0000030607-0203 020607: 020907 6ｦ001090409 020ｷ307 07 09020607 06 0203o08 0300 02000ｸ70206026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0 0402o07 02o00 陦 02090ｹ0 0900fi0406 0ｹ0 0ｸ709006ｧ9 0ｹ0, 0209 000002 03036ｦ00300060409 020ｷ307 040ｸ70402090007020ｷ307 0ｸ709006ｧ9 0ｹ0, 020907 0007 0ｸ70707000ｷ30409 02090ｹ0 040ｸ700000002o046ｧ80ｹ0 020ｷ307 040300070607 02 06 02o0ｸ7 03fi03o0ｸ7 02090ｹ0 6ﾑ8.6ﾑ8. 6ｾ46ｦ000080ｷ307 0000 apple03fi0408 0209 000003 閨0209 02090ｹ0 6ﾑ8apple060203oapple6ｧ80ｹ0 apple03o6 503 鐶pple0002 06 fi0206 02 07 陦 00 閨0309 6ｧ9040ｷ30ｹ0 04030006 0403o6ｦ007 40 0403fi0706 0906 07 02 036ｦ06 7o0ｸ707 0209 06 08o0307 0000 02 0ｸ7apple070304o0702 0203070209-00 閨0309 02fi04o fi04o07 08o0307 02o ﾞ6ﾑ809 fi04o 02 06 02060ｹ0 00apple0007 6ｦ00400060ｹ0 04020907 apple 03o046ｧ8 06 0203o08 0300 02000ｸ70206-026ｧ80ｹ0 apple00036ｧ903 036 7090ｹ0. O 02. Ager 0600030ｷ3026ｧ803090200 00 07 03 00appleo03o6ｦ004 07 07 096ｧ907o0ｸ707 apple0003060404fi020003, 06040200 07 0900080ｸ7030ｷ303006ｧ9 02o 04070400 0402o07 02o00 陦 02090ｹ0 0ｸ709006ｧ9 0ｹ0. ﾞ07 080003fi000007o0ｹ0 04020907 02070409, appleo0ｸ7 apple 03 0209036ｧ803090200 apple03fi0408-02 0400 o03060400 閨07000ｹ0 0ｸ7applefi 閨0702 0109 040603000ｹ0 0906 apple0003060402o036ｧ8 020ｷ307 apple 070607 0ｸ709006ｧ9 0ｹ0, o Friedrich Breitenstein, 0903fi00 03o0ｹ0 02090ｹ0 O0007 0ｹ0 04030704090ｹ0 02090ｹ0 EFPIA 0906 0209 0406006ｦ0030ｸ7070409, 02fi07060400 fi0206 09 6ｦ001090409 020ｷ307 00apple0007 6ｦ004000ｷ307 04020907 06 0203o08 03-00 02000ｸ70206026ｧ8 apple00036ｧ903 036 709 006ｧ907 06 03000000030606 090ｹ0 0906 0209 00 0203oapple03fi0300040009 00apple06020ｸ7046ｧ9 02090ｹ0 06006ｦ0030ｸ70704090ｹ0. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 29

13EFPIA ANNUAL MEETINGS ATHENS 2003 0809006ｧ9 02 06 0406006ｦ0030ｸ7070409-06fi03o0ｹ0 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 05 apple03 鐶pple0006 07 096ｧ9070006 04 08 閨0ｹ0 fi0206 02 02 0607o02fi00 08070300 02 00appleo03o6ｦ007 07 apple 6ｧ901o0ｸ707 040900 07020602fi 03fi03o 040209 6 50003026ｧ90ｷ30409 02090ｹ0 appleo06fi020902 0ｹ0 02 06 02090ｹ0 appleo020003000400 020602fi020902 0ｹ0 020ｷ307 0ｸ7apple09030004060607 02090ｹ0 apple 03o046ｧ80ｹ0 0ｸ709006ｧ9 0ｹ0 02 03060ｹ0 02 06 040209 040ｸ707o0306026ｧ8 02o06070ｷ30706026ｧ8 000ｸ7090000036ｧ9. 006ｾ40ｸ70700apple060ｹ0, apple03o020003 06fi020902 00 0ｹ0 006ｧ907 06 07 07-09070ｷ303060403006ｧ9 09 08 0300 02000ｸ70206026ｧ8 6 506o000904 076ｧ9 閨03000ｸ707 0ｹ0 0ｷ30ｹ0 040ｸ7-070200030004026ｧ80ｹ0 04020907 apple 03o046ｧ8 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0 040209 06000ｸ7030ｸ7-00 閨0709 6ﾑ80ｸ70306apple0903, 006ｧ9apple00 o 02. Breitenstein. 00 ﾇ 00apple06020ｸ7046ｧ9 02o0ｸ7 040400 6ｧ9o0ｸ7 06006ｦ0030ｸ70704090ｹ0 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 0402o 08 0300 02000ｸ7020602fi 02o00 陦 03 0001 03020903006ｧ9 applefi 0209 06 04080703060409 02090ｹ0 06 0300040600fi020902 0ｹ0 020ｷ307 02 0607o02fi000ｷ307 08 030007020ｷ307 0402060ｹ0 07 閨000ｹ0 0ｸ7applefi 閨0702 0109 040603000ｹ0, 040ｷ3036ｧ90ｹ0 07 06 02 03 0403o6ｦ007 02 030000 閨0306 02 06 02 07fi000600 0602 060600 02 020ｷ307 6ﾑ80ｸ7030ｷ3apple 0ｸ8020607 0002 060300060607, appleo0ｸ7 6 5 046ｧ9ｨBo0702 06 04020907 閨03000ｸ707 03 6ｧ8030ｷ30400 o 02. Breitenstein. 09 03 03 閨02o0ｸ70000 02o0ｸ70ｹ0 026ｦ00306o0ｸ70ｹ0 0701o07000ｹ0 02o0ｸ7 apple03o6 5030900 0206-0400o6ｦ0 appleo0ｸ7 07 apple026ｦ00403090200: 09 ﾇ appleo0ｸ7046ｧ9 030ｸ703006ｧ904000ｷ307 0906 020907 0ｸ709006ｧ9 0ｷ30ｹ0 閨07 0100040ｷ303060402fi ｨB6ｧ8020900 apple03060ｹ0 0702 07 020307 02o 090009o07fi0ｹ0 fi0206 09 0ｸ709006ｧ9 03000ｷ303006ｧ902 06 apple000306o046ｧ8 00030706026ｧ80ｹ0 appleo03060206026ｧ80ｹ0. 09 030402fi04o, 06 06 6ｧ9020003 09 040ｸ709020002030600 閨0709 06006ｦ0030ｸ7070409 02090ｹ0 6ﾑ8.6ﾑ8., 03 閨020006 06 040ｸ707o0306 0207 03 閨00 02 0ｸ709006ｧ9 0ｹ0 fi04o 02 006ｧ9 07030309 06006ｦ0030ｸ7070409 0402o apple 03000303fi07. 09 00 ﾞ0700apple06036ｦ0000902000ｹ0 0007 閨03090006000ｹ003 02090ｹ0 000002 6 5 0206026ｧ80ｹ0 apple000306fi o0ｸ7 04 ｯ 0ｸ702 閨0ｹ0 02060ｹ0 02o06070ｷ3076ｧ9000ｹ0 006ｧ907 06 09 o0602o07o0006026ｧ8 02036ｧ90409, 02o06070ｷ3070602 閨0ｹ0 070604fi020902000ｹ0, 06006ｦ0030ｸ7070409 020ｷ307 06 08o030607 000604o 6ｧ800 02o0ｹ0, 04 000903fi0ｹ0 6 5 0300fi0ｹ0 070001 030209046ｧ9 0ｹ0 02 06 000902030900 020602fi020902. 6ﾒ2o 090009o07fi0ｹ0 fi0206 o06 040603000ｹ0 02090ｹ0 6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 03070ｷ304090ｹ0 6 5036ｧ90402o0702 06 0ｸ7026ｧ8 0209 04020609006ｧ8 0007 00 閨040ｷ3 00apple 07 06 00fi03080ｷ3-04090ｹ0 020ｷ307 06020607 02o0ｸ70ｹ0 040ｸ70402090007020ｷ307 0ｸ709006ｧ9 0ｹ0 0007 00apple060203 鐶pple0006 apple036ｧ8 000002 08o0307 0007fi0ｹ0 apple03o026ｦ0appleo0ｸ7 02 020703030903o0ｸ7 0906 0008 0300o096ｧ8 0400 fi03 02 00o0702 閨03. 09 ﾇ 0ｸ709006ｧ9 070206apple03o040ｷ3apple006ｦ00006 apple00036ｧ9appleo0ｸ7 02o 4,5% 02o0ｸ7 ﾞ6ﾑ809 0402060ｹ0 0ｸ7applefi 閨0702 0109 040603000ｹ0 02 06 02o 06apple03070406o 0ｸ702o6ｦ0 02o0ｸ7 appleo04o0402o6ｦ0 0402060ｹ0 apple0003060404fi020003000ｹ0 010603000ｹ0 09 閨0309. 08applefi 020907 apple03o00applefi03000409, fi0206 o06 apple 03o04 閨0ｹ0 03 00appleo03 閨04o0ｸ707 07 0702 appleo02030603o6ｦ007 0402060ｹ0 0ｸ701 07fi000007000ｹ0 apple 06026ｧ80400060ｹ0, o 02o00 陦 0ｹ0 0ｸ7apple09030004060607 0ｸ709006ｧ9 0ｹ0 07 00 閨070002 06 07 閨040006 030ｸ70300o6ｦ00ｹ0 0707apple020ｸ701090ｹ0 07070ｷ3 02o0ｸ7 00 閨04o0ｸ7 fi03o0ｸ7. 030402fi04o 02 02o07 6ｦ00306 appleo0ｸ7 03 06 026ｧ903000702 06 applefi 02o 0900fi0406o 02o00 陦 03 006ｧ907 06 apple000306o03060400 閨07 02 06 03 apple 0602006ｧ9-02 06 applefi030ｸ70209 060003070304090409 020ｷ307 applefi030ｷ307. 09 6ﾒ2o 020007fi 000002 016ｦ0 080603o o016ｧ9 0ｹ0 02 06 apple03 0900 020602fi020902 0ｹ0 02fi04o 02o06070ｷ307060207 fi04o 02 06 appleo030602060207 006ｧ907 06 040900 07020602fi fi04o07 08o0307 04020907 ﾞ07 02o0306026ｧ8 06006ｦ0030ｸ7070409. 6ﾒ2o 07 apple0002070006 02 07006ｧ90ｹ0 04036ｧ800 02 0402o apple03fi6 5030900 0007 006ｧ907 06 09 00fi0709 036ｦ00409. 030402fi04o, 00appleo03o6ｦ007 07 04030900 02o o020903o6ｦ007 apple03o0903070000 02 00apple0600fi03080ｷ304090ｹ0 02 06 07 096ｧ907o0ｸ707 00apple0007 6ｦ00400060ｹ0 04020907 06 020306026ｧ8 02 06 06 0400060306040206026ｧ8 00040ｷ302000306026ｧ8 o006ｧ8, apple0003000ｸ70300030607o0702 0ｹ0 02oapple0602o6ｦ00ｹ0 applefi03o0ｸ70ｹ0 0906 020907 apple0309030ｷ3006ｧ8 6 5000302060ｷ300 閨070ｷ307 09 030607 02 06 09000003o000604036ｧ90ｷ307. 6ｾ402060ｹ0 apple03o0909o6ｦ0000007000ｹ0 06000ｸ7036ｦ0070400060ｹ0 02090ｹ0 6ﾑ86ﾑ8 09 04030900 02o fi- 02090409 02090ｹ0 046ｦ00902030604090ｹ0 0402fi04000ｸ700 0402060ｹ0 000002 08o03 閨0ｹ0 02 06 02o apple0003066 5070303o07. 05 apple03 鐶pple0006 6ｧ9040ｷ30ｹ0 07 0402000802o6ｦ00000 07 09 0ｸ709006ｧ9 03 閨040006 6ｧ8 fi0406 00apple6ｧ904090009 07 09070603060409 0906 020907 02oappleo03 閨02090409 apple0003060800-030006 020607 02o07 0ｸ7036ｧ90ｷ307. ﾞapplefi 080409 02000600 閨07080ｸ7 09. 09 04020803070209 Head of Regulatory Affairs Pfizer Hellas 30 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13096ｧ8070ｸ700 applefi 0208 縺00070602fi 04/07026ｧ8 096ｧ8070ｸ700 applefi 0208 縺00070602fi 04/07026ｧ8 02090ｹ0 EFPIA 02. Brian Ager ﾞ036ｧ807 26-28 09 0ｹ1080ｸ7 2003 26-28 09 0ｹ1080ｸ7 2004 04080ｸ76 5036ｧ90708 02090ｹ0 EFPIA 02. Brian Ager ﾞ036ｧ807 26-28 09 0ｹ1080ｸ7 2003 26-28 09 0ｹ1080ｸ7 2004 04080ｸ76 5036ｧ90708 ﾞapplefi 080409 02080ｸ7 02000600 閨07080ｸ7 6ｾ4. 09000307 04/07020306 6ﾑ8apple0604020900080706020607 05000007020ｷ307 ﾇ 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ70409 02090ｹ0 EFPIA 04020907 ﾞ036ｧ807 陦0ｷ30400 020907 000ｸ702 06036ｧ9 0400 0ｸ7apple006ｦ0030ｸ707o0ｸ70ｹ0 036ｧ86 7090ｹ0 appleo080704000ｷ307 0203 020602o6ｦ00ｹ0 03000602o0ｸ70309o6ｦ00ｹ0, 0002apple03o0406appleo0ｸ70ｹ0 020ｷ307 040300070607, 02 0900 0ｸ802o6ｦ00ｹ0, 0900o0406o09030708o0ｸ70ｹ0 02 06 070602 02 04020003 閨0409 02090ｹ0 08 0300 02000ｸ70206026ｧ80ｹ0 6 506o000904 076ｧ9 0ｹ0 0003006ｦ007090ｹ0 07 040ｸ707 07020903o6ｦ007 02 06 07 0702 03030701o0ｸ707 applefi6 700060ｹ0 0400 apple0309030603 03000007020ｷ307. 0900 020907 000ｸ702 06036ｧ9 02o0ｸ7 00o0302 0400o6ｦ0 020ｷ307 25 0403fi070ｷ307 applefi 020907 6ｧ9 030ｸ70409 02090ｹ0 EFPIA 040209 040603 02o0ｸ7 ﾞ04020309apple06o6ｦ0, 02090ｹ0 0809006ｧ9 0ｹ0 02 06 02o0ｸ7 ｦﾐappleappleo0203070209 07-0203 閨01 0000 0402 00apple0602006ｦ00900 02 25 0403fi070ｷ307 閨03000ｸ707 0ｹ0 0906 020907 07 0207030ｸ76 709 07 閨0ｷ307 08 030007020ｷ307 02 06 0402060ｹ0 000ｸ702 06036ｧ9000ｹ0 0906 020907 apple0003 0602 閨030ｷ3 0707apple020ｸ70109 08 030007020ｷ307 0906 020907 0703030ｷ3applefi020902. O06 040ｸ707036ｧ802000ｹ0 6ｧ802 07 06 0006 00060ｹ0 0906 ｨB0ｷ30702 07 閨0ｹ0 040ｸ7ｨB09026ｧ80400060ｹ0 02 06 040703060ｹ0 04020907 000303090706026ｧ8 080603o0100076ｧ9 02 06 02o07 02 03fi 02 0603fi. 6ﾑ8apple0603 閨01 0000 0ｷ30ｹ0 03 閨00 02o0ｸ7 040ｸ70700 036ｧ9o0ｸ7 020907 006ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ003 046ｦ000080ｷ3-07 02 06 0000 02o 07026ｧ90402o0604o apple03fi0903 0000 02090ｹ0 Commission 0906 02o 2003. 6ｾ402 workshops 02 06 02o 040ｸ707 陦0306o 閨09060700 0707030ｸ70409 020ｷ307 apple03o6 503090007020ｷ307 appleo0ｸ7 0ｸ7apple070304o0ｸ707 04020907 apple03fi046 5 0409 020ｷ307 040300070607 0402 07 陦 08070300 02 02 06 04020907 0602 07fi020902 02090ｹ0 02o06070ｷ3076ｧ9 0ｹ0 07 apple 03 閨040006 6ｧ904000ｹ0 000ｸ702 06036ｧ9000ｹ0 apple03fi046 5 04090ｹ0 0402060ｹ0 0ｸ7apple090300046ｧ9000ｹ0 0809006ｧ9 0ｹ0 0400 fi03o0ｸ70ｹ0 02o0ｸ70ｹ0 04030007006ｧ90ｹ0. 6ﾒ2 00 閨0309 02090ｹ0 EFPIA 006ｧ904 07 020907 000ｸ702 06036ｧ9 07 040ｸ7006 5070303o0ｸ707 030002060207 0402060ｹ0 040ｸ7ｨB09026ｧ80400060ｹ0. 05 閨030ｷ3 07 000ｸ704 030604026ｧ8040ｷ3 02o07 6ｾ4026ﾑ86ﾑ8 0906 020907 030003006ｧ8 0ｸ7appleo o046ｧ8 appleo0ｸ7 00 0ｹ0 00apple00086ｦ003 0100 02 06 020907 040900 070206026ｧ8 040ｸ7006 5o036ｧ8 02o0ｸ7 04020907 o030907070ｷ30409 02090ｹ0 0002 6ｧ8030ｷ304090ｹ0. 7002 07 000009070309 04 0307 0906 00 0ｹ0 07 閨0303o0ｸ70000 0402o 036ｧ90207o 02o0ｸ7 6ﾑ80ｸ7030ｷ3apple 0ｸ802o6ｦ0 09o030602060400o6ｦ0. ﾒo0602060702 0ｹ0 0402o 00 閨0303o07 03 6ｧ8030003 07 04 0ｹ0 07 02o060706040ｷ3 fi0206 09 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ70409 02090ｹ0 EFPIA 0906 02o 2004 03 096ｧ9070006 26-28 09 6ｧ9o0ｸ7 0402o 04o0ｸ76 5036ｧ907o 0400 040ｸ707000309 046ｧ9 0000 020907 IPHA, 02o07 ｦﾐ0303 07 0602fi 6ｾ46ｦ007 000400o 02 0300 02000ｸ70206026ｧ80ｹ0 0806o000904 076ｧ9 0ｹ0. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 31

13EFPIA ANNUAL MEETINGS ATHENS 2003 00036ｦ00402000ｹ0 ﾞ0609 6ｧ9080ｸ7 0900030709080ｸ70ｹ003 ﾞ036ｧ807, 30 09 0ｹ1o0ｸ7 2003 ｨC 00036ｦ00402000ｹ0 02o0ｸ7 ﾞ0609 6ｧ9o0ｸ7 0900030709o0ｸ70ｹ003 險B0904 07 apple0003060404fi020003o06 applefi 500 6ﾑ80ｸ7030ｷ3apple 6ｧ9o06 0903fi00 03o06, 縺00070602o6ｧ9 0406000ｸ7030ｸ70702 閨0ｹ0 02 06 070602 02 04020003 閨0409 020ｷ307 000009 036ｦ00200030ｷ307 08 0300 02000ｸ70206020607 00apple06040006036ｧ804000ｷ307 02 06 6ｾ40ｸ707 閨04000ｷ307 02090ｹ0 6ﾑ80ｸ70306apple090ｹ0 appleo03 006 50707o0702 0ｹ0 0006 01 閨04 040209 6 503 0607 appleo0ｸ7 apple03o04 閨08000300 o 6ｾ4026ﾑ86ﾑ8 090000070209 applefi 6ﾑ8030307. H 0002 6ｧ8030ｷ30409 apple03 0900 02oappleo066ｧ803090200 0000 08o03006ｧ8 0209 040900 070206-02fi02000309 00026ｧ80406 040ｸ707070702090409 02o0ｸ7 08 0300 02000ｸ7020602o6ｦ0 020307 o0ｸ7 04020907 6ﾑ80ｸ70306apple09, appleo0ｸ7 080603o01 閨07090400 apple03fi0408 02 0906 apple03060209 08o0307 09 040603 00 0ｹ0: 020907 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ70409 02090ｹ0 EFPIA (6ﾑ80ｸ7030ｷ3apple 0ｸ8026ｧ80ｹ0 O00o04appleo07 6ｧ9 0ｹ0 6ｾ40ｸ707 閨04000ｷ307 02 06 02 0300 02000ｸ70206-020607 6ﾑ8apple06040006036ｧ804000ｷ307) 09 oappleo6ｧ9 06o0309 070603090200 0400 040ｸ707000309-046ｧ9 0000 02o07 6ｾ46ｦ007 000400o 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 6ﾑ8030307 o0ｹ0 (6ｾ4.02.6ﾑ8.6ﾑ8.). O 0903fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02. 縺0006030906o0ｹ0 6ｾ40ｸ70206 070702090ｹ0 02 030ｷ304fi- 03060400 02o0ｸ70ｹ0 apple 03000ｸ703060402o00 閨07o0ｸ70ｹ0 02 06 000ｸ704 036ｧ90402090400 06 06 6ｧ9020003 02o07 0903fi00 03o 02 06 02o 04.6ｾ4. 02090ｹ0 EFPIA appleo0ｸ7 apple03 0900 02oappleo6ｧ909-04 07 04020907 6ﾑ8030307 020907 6ﾑ8026ｧ80406 縺000706026ｧ8 6ｾ40ｸ707 閨03000ｸ7046ｧ8 02o0ｸ70ｹ0. 08apple006ｦ0030ｸ707o0ｹ0 0906 020907 02fi04o 00apple06020ｸ7040900 閨0709 06o030907070ｷ30409 02090ｹ0 6 503 06070ｹ0 6ｧ802 07 o ﾞ070206apple03fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02. 6ｾ4apple6ｦ003o0ｹ0 08 03030703090ｹ0. 6ﾒ209 6 503 0607 026ｧ9000904 07 0000 020907 apple 03o0ｸ7046ｧ9 02o0ｸ70ｹ0 o 0903fi00 03o0ｹ0 02090ｹ0 EFPIA Sir Tom McKillop, o 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 02090ｹ0 EFPIA 02. Brian Ager, 02 03060ｹ0 02 06 09 02 Marie Claire Pickaert 07 apple03090306020306 縺000706026ｧ8 0406000ｸ7036ｦ007020306 02090ｹ0 EFPIA. 09 03000ｸ703 閨030904 07 00apple6ｧ904090ｹ0 o ﾞ070206apple03fi00 03o0ｹ0 02o0ｸ7 6ﾑ8O02 02. 05. ﾒ0008 03070ｹ0, o 0903fi00 03o0ｹ0 02o0ｸ7 09 0700030309076ｧ9o0ｸ7 02 0300 02000ｸ7020602o6ｦ0 6ｾ40ｸ70303fi09o0ｸ7 02. 0409006ｧ80203090ｹ0 08 09060ｷ307070ｹ0, o 0903fi00 03o0ｹ0 6ｾ4 ﾞ026ﾑ86ﾑ8 02. 09 6ｦ003o0ｹ0 縺06 0707 02fiappleo0ｸ703o0ｹ0, o 0903fi00 03o0ｹ0 02090ｹ0 09 070003036ｧ80706 0ｹ0 03070ｷ304090ｹ0 02 0300 02oappleo060607 ﾞ07020604020307020909o0ｹ0 ﾞ0702. ﾞ0ｸ70900030607fi0ｹ0, o 0903fi00 03o0ｹ0 02090ｹ0 09 070003036ｧ80706 0ｹ0 03070ｷ304090ｹ0 02 0300 02o6 506o0009-04 076ｧ9 0ｹ0 05. 6ﾒ2036ｦ0080ｷ307, o 00apple6ｧ9020600o0ｹ0 0903fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 0403. 000ｷ3076ｧ9 0ｹ0 ﾒ03 04040703090ｹ0, 02 03060ｹ0 02 06 縺00070602o6ｧ9 0406000ｸ7030ｸ70702 閨0ｹ0 020ｷ307 040900 07020602fi0200030ｷ307 08 0300 02000ｸ70206020607 0002 060300060607 04020907 6ﾑ8030307. O0602o 0004applefi02000ｹ0 6ｧ802 07 02o 0406o060209020602fi 6ｾ40ｸ7006 5o6ｦ00306o 02o0ｸ7 6ｾ4026ﾑ86ﾑ8, o 0903fi00 03o0ｹ0 02. 縺0006030906o0ｹ0 6ｾ40ｸ70206 070702090ｹ0 o06 02. 6ﾒ20704o0ｹ0 ﾒ0ｸ70306 02o6ｦ0, 08 046ｧ903090ｹ0 03000607 0ｹ0, o06 ﾞ070206apple03fi00 03o06 02. 6ｾ4apple6ｦ003o0ｹ0 08 03030703090ｹ0, 030602fi03 o0ｹ0 09 07 04040702090ｹ0, ﾒ0ｷ3070402 07026ｧ907o0ｹ0 09apple 0702ｨB6ｧ80ｹ0, 020602090ｹ0 6ｾ4 02000303 036ｧ9 090ｹ0, 6ｾ402 閨08 07o0ｹ0 6ｾ4020008 076ｧ9 090ｹ0, 0406o076ｦ004090ｹ0 020603060602090ｹ0, 02 06 02 09 閨0309 02o0ｸ7 046ｾ4 o06 02. 09 04040703090ｹ0 ﾞappleo0402o036ｧ9 090ｹ0, ﾞ07020607090ｹ0 08o0906 02ｨB6ｧ80ｹ0, 09 07 09060602090ｹ0 縺0003o030ｸ7000702o0ｹ0, ﾒ060402 0ｹ0 6ﾑ80ｸ70306apple6ｧ9 090ｹ0, 09070306o0ｹ0 ﾒ0702040602 0ｹ0, o 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 02o0ｸ7 6ｾ40ｸ707 閨0400o0ｸ7 02. 020602090ｹ0 09 0909 03o6ｦ004090ｹ0 02 06 09 02. 6ｾ4. 09000307. 32 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13O 0903fi00 03o0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02.. 6ｾ40ｸ70206 070702090ｹ0 (Menarini) O 縺00070602fi0ｹ0 04/07026ｧ80ｹ0 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02. 02. 09 0909 03o6ｦ004090ｹ0 O 06o0309 070ｷ3026ｧ80ｹ0 02090ｹ0 0002 6ｧ8030ｷ304090ｹ0 02 06 ﾞ070206apple03fi00 03080ｹ0 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02. 6ｾ4apple. 08 03030703090ｹ0 (NOVARTIS) ( applefi 00010607) 08 02.. 6ｾ40ｸ70206 070702090ｹ0 0000 020807 Sir Tom McKillop 02 06 020807 02. C. Timelin (AstraZeneca) O 6ｾ402. 6ｾ4020008 076ｧ9 090ｹ0 (Boehringer Ingelheim), A070206apple03fi00 03080ｹ0 6ｾ4026ﾑ86ﾑ8 0000 020807 0903fi00 0308 02.. 6ｾ40ｸ70206 07070209 02 06 0209 046ｦ0ｨB0ｸ709fi 02080ｸ7 O 縺00070602fi0ｹ0 04/07026ｧ80ｹ0 02090ｹ0 EFPIA 02. 08rian Ager O 02. 02. 6ｾ4 020003 036ｧ9 090ｹ0 A070206apple03fi00 03080ｹ0 6ｾ4026ﾑ86ﾑ8 (Janssen-Cilag), 0000 020807 0903fi00 0308 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02.. 6ｾ40ｸ70206 07070209 02 06 020807 6ﾑ8apple6ｧ902060008 0903fi00 0308 0403.. ﾒ03 04070309 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 33

13EFPIA ANNUAL MEETINGS ATHENS 2003 ﾇ ﾞ07 apple03090306020306 縺000706026ｧ8 04/07020306 02090ｹ0 EFPIA 02 Marie-Claire Pickaert 0000 020807 02. 6ｾ4apple. 08 0303070309 02 06 020907 02 6ｾ4. 09000307 O 02. 04. 08 09060ｷ307070ｹ0, 0903fi00 03o0ｹ0 02o0ｸ7 09026ｾ4 02 06 o06 ﾞ070206apple03fi00 03o06 02o0ｸ7 6ｾ4026ﾑ86ﾑ8 02. 02. 09. 縺0003o030ｸ7000702o0ｹ0 (09.03. 縺6ﾑ806O 0809 ﾞ6ﾒ2O6ｾ4) 02 06 02. 03. 09 07 04040702090ｹ0 (GSK) (Aapplefi 00010607) 08 02. 04. 020603060602090ｹ0 (Farmaserv Lilly), 08 ﾞ070206apple03fi00 03080ｹ0 02080ｸ7 6ｾ4026ﾑ86ﾑ8 6ﾒ2. ﾒ0ｸ70306 02o6ｦ0 (Organon) 縺00070602fi0ｹ0 縺03 0000 02 陦 0ｹ0 02o0ｸ7 6ｾ4026ﾑ86ﾑ8, o 02. 086ｧ9 03 0ｹ0 (Famar) 02 06 o 05. ﾞ00apple 02ｨBfi0903o0ｸ7 (09.6ｾ4.02.) O 02. 04. 09 0ｸ70308000702090ｹ0 (Pharmanel), o 02. ﾆ00036 5 020702090ｹ0 (Wyeth) 02 06 08 02. 09 07 04040702090ｹ0 (GSK) O 02. 09. ﾞapple08040208036ｧ9 090ｹ0 (Abbott) 00 閨03080ｹ0 02080ｸ7 046ｾ4 02080ｸ7 6ｾ4026ﾑ86ﾑ8 0000 020907 02 ﾞapple08040208036ｧ9 09, 020807 02. 03. ﾒ080ｸ7020406 0707 0903fi00 0308 02080ｸ7 096ｾ408 ﾞ ﾒ, 020807 02. Dirckx (Roche) 02 06 020807 02. ﾒ. 0302fi0302 (Roche) O 0903fi00 03o0ｹ0 02090ｹ0 096ﾑ802 ﾞ07020604020307020909o0ｹ0 ﾞ0702. ﾞ0ｸ70900030607fi0ｹ0 34 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13O 02. 05. ﾒ0008 03070ｹ0, 09 閨03080ｹ0 02080ｸ7 046ｾ4 02o0ｸ7 6ﾑ8O02 ﾇ 02 6ﾑ8. 06000204 閨0009 04/07020306-08apple. ﾞ0707apple020ｸ701090ｹ0, 08 02. 09. 縺06 0707 02fiapple080ｸ703080ｹ0 (Vianex) 02 06 09 02 ｦﾐ. 01 02ｨB08apple086ｦ003080ｸ7 縺0007. 04/07020306 02080ｸ7 08apple. ﾞ0707apple020ｸ701090ｹ0 ﾌ 02. Trevor Jones (ABPI) 02 06 08 02.Roger Bolton O 02. ｦﾐ. 04036ｧ90204 0ｹ0 0000 0209 046ｦ0ｨB0ｸ709fi 02080ｸ7 O 02. 04. 020603060602090ｹ0 0000 02060ｹ0 020ｸ7036ｧ9000ｹ0 09. ﾒ0702040602 (Faran), 02. 6ｾ4 02000303 036ｧ9 09 02 06 03. 09 07 0404070209 O 02. 02. 6ｾ4 020003 036ｧ9 090ｹ0 A070206apple03fi00 03080ｹ0 6ｾ4026ﾑ86ﾑ8 (Janssen-Cilag), 08 02. 09. ﾒ0702040602 0ｹ0 00 閨03080ｹ0 02080ｸ7 046ｾ4 (FARAN), 09 02 09. 6ｾ402080ｸ7030803060702080ｸ7 02 06 08 02. 05. 6ﾒ2036ｦ0080ｷ307 (Elpen) 0903fi00 03080ｹ0 02090ｹ0 096ﾑ802 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 35

13O 02. 09. Pluess (Novartis) 0000 0209 046ｦ0ｨB0ｸ709fi 02080ｸ7 EFPIA ANNUAL MEETINGS ATHENS 2003 ﾌ 02.. 04fi0206080ｹ0 (0809S) 0000 020807 0903fi00 0308 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02.. 6ｾ40ｸ70206 07070209, 020807 02. ﾒ. 09apple 0702ｨB6ｧ8 (UCB pharma) 00 閨03080ｹ0 02080ｸ7 046ｾ4 02080ｸ7 6ｾ4026ﾑ86ﾑ8 02 06 08 02. 09. 6ｾ402 040607fi0ｹ0 (0809S) O A070206apple03fi00 03080ｹ0 02090ｹ0 EFPIA Jean Francois Deheq 0000 0209 046ｦ0ｨB0ｸ70908 02080ｸ7, 08 Michel Labie, (Sanofi-Synthelabo) A070206apple03fi00 03080ｹ0, 08 02. ﾞ0702. 08080906 02ｨB6ｧ80ｹ0 (Sanofi-Synthelabo) 00 閨03080ｹ0 02080ｸ7 046ｾ4 02080ｸ7 6ｾ4026ﾑ86ﾑ8 ﾇ 02 Maria Teresa Rico (shering Plough) 0000 02o 046ｦ0ｨB0ｸ709fi 02090ｹ0, 09 02 Aracelia Vila 02 06 o 02. O ｯNeil (Wyeth) 36 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13This SFEE Newsletter includes the main presentations covered in the four Newsletters issued by EFPIA on the occasion of the EFPIA Annual Assembly. The English addendum of this SFEE Newsletter includes the five EFPIA press releases issued during the Annual Meetings. "EUROPE MUST DO MORE TO ENCOURAGE INNOVATION FOR THE BENEFIT OF PATIENTS" SAYS SIR TOM MCKILLOP Athens (Greece), 27 May 2003 ｨC At the Annual Meetings of the European Federation of Pharmaceutical Industries and Associations (EFPIA), Sir Tom McKillop, EFPIA President and Chief Executive of AstraZeneca, reviewed progress on priority issues for the pharmaceutical industry in Europe. Sir Tom stressed the need to strike the right balance between Health, Social and Industrial Policies: "Patients in Europe today have increasingly come to expect new and better medicines that will help them live longer, better quality and more productive lives than ever before. Through our intensive research, the pharmaceutical industry can offer them tremendous opportunities and choices in their personal healthcare and well-being. As the European Commission acknowledged in 1994, the legitimate concern to limit public expenditure and healthcare costs ｨC of which it must be remembered that medicines represent only a small fraction ｨC must not be allowed to jeopardize the future of pharmaceutical research in Europe. Public health and health care systems have nothing to gain from a weakening of Europe ｯs research-based industry. On the contrary, as one of the key contributors to scientific and medical progress, Europe ｯs economy and society, the success of the pharmaceuticals sector is crucial to the wealth and health of Europe". " ﾇ 6ﾑ80ｸ70306apple09 02090ｹ0 0809006ｧ9 0ｹ0: 03 閨000ｹ0 0ｸ707 02fi020902000ｹ0 0906 02o0ｸ70ｹ0 04030007006ｧ90ｹ0 046ｧ8000003 " 6ﾒ2o 070ｷ302 閨030ｷ3 040ｸ707 陦0306o 06o0309 070603090200 0402 apple03 6ｧ90406 02090ｹ0 縺000706026ｧ80ｹ0 6ｾ40ｸ707 閨03000ｸ704090ｹ0 02090ｹ0 EFPIA appleo0ｸ7 閨096ｧ90700 04020907 ﾞ036ｧ807 0402060ｹ0 26 ｨC 28 09 0ｸ8o0ｸ7 2003 0400 040ｸ707000309 046ｧ9 0000 02o07 6ｾ4026ﾑ86ﾑ8 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 37

13EFPIA ANNUAL MEETINGS ATHENS 2003 Competitiveness: European Competitiveness: European pharmaceutical industry at risk pharmaceutical industry at risk Data for 2002 confirm that the European pharmaceutical industry remains one of Europe ｯs best high-technology sectors. It performs well on most standard measures such as employment (with 582.500 qualified people), production (worth 160bn at exfactory prices), R&D (19.8bn invested) and trade surplus (with a positive balance of 40bn). However, key benchmarking indicators also highlight the vulnerability of the pharmaceutical industry in Europe and its steady decline in competitiveness compared to the US, which has increased its dominance as an attractive site for R&D and a ｮlocus of innovation ｯ. The European pharmaceutical industry, which has for many years been the world ｯs leading inventor of new medicines, seems to be marking time as its share of R&D investment declines under economic and regulatory pressure. High failure rates, the significant cost of clinical trials and the amount of time needed to get approval by the regulatory authorities are the primary reasons for the exponential increase in pharmaceutical R&D costs. G10 and Review of the EU pharmaceutical Legislation: the way forward As a response to the general concern caused by the deterioration of the industry ｯs competitiveness, the G10 process marks an important first step by establishing a discussion platform that involves and commits the various interested parties (Commission, Member States, Industry, Patients, Mutualities) to a set of 14 recommendations. EFPIA now expects the upcoming Communication from the European Commission to convert these recommendations into practical steps that will positively contribute to a pro-research environment in Europe. "G10 gives us a foundation for the way forward to improve the European market environment and address issues raised by the enlargement of the European Union. The review of medicines legislation offers the chance to consolidate progress towards a world class European regulatory framework", declared Sir Tom. It would be too simplistic to attribute the deterioration of the European pharmaceutical environment to a single factor. As a whole, Europe remains less attractive for R&D investments than other regions, the US in particular. The economic and healthcare environments, the science base, the investment conditions, the regulatory framework, and societal attitudes towards new technologies all contribute. "US patients are willing to embrace innovation ｨC they want to be informed and to have the benefits of new approaches to healthcare", said Sir Tom. "In Europe, research shows that patients seek increased access to healthcare information - people also want greater participation in health care policies. But Europe ｯs healthcare systems are reluctant to adopt new technologies - they do not seem prepared for the current and future healthcare needs of a European ageing population". G10 and Review of the EU pharmaceutical Legislation: the way forward For any further information, please visit the EFPIA website www.efpia.org "For the first time in many years, there is a glimmer of hope that the issues really affecting the pharmaceutical industry are being discussed openly and constructively". "We need to maintain a high level of intellectual property protection, as well as an efficient and worldclass regulatory system in Europe allowing patients to reap the benefits of therapeutic progress more quickly. We need less bureaucratic government intervention which stifles competition, discourages innovation and creates significant inequity among European patients' access to new therapies. All of us - governments, regulators, industry, healthcare providers, and above all patients - have an opportunity to work together to deliver a vibrant pharmaceutical industry for the benefit of the 450 million citizens in an enlarged Europe", concluded Sir Tom. 38 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13REVIEW OF EU PHARMACEUTICAL LEGISLATION: EFPIA CALLS ON MEMBER STATES TO ADOPT WORLD CLASS REGULATORY FRAMEWORK FOR INNOVATIVE MEDICINES Ahead of the EU Health Council (2-3 June), the European Federation of Pharmaceutical Industries and Associations (EFPIA) reminds EU Member States that a key objective for the review is to help the pharmaceutical industry find new and better treatments for the benefit of patients. "EU Member States have an opportunity to set a more favourable legal framework for research and patients for the next 10-15 years", said Brian Ager, EFPIA Director General. "The Commission ｯs initial proposal presented a balanced package. There is growing evidence of the relative decline of European industry ｯs competitiveness in the pharmaceutical sector. This review is an opportunity to contribute to improving the situation". Key priorities for EFPIA are: 09 Regulatory Data Protection ｨC Industry supports 10+1 years data protection as endorsed by G10 ｨC This will be an essential driving force for research in Europe. 09 Regulatory Procedures - Industry supports improvements to ensure a strong and effective EMEA/Centralised Procedure, together with improvements to facilitate business operations. 09 Business Flexibility - Industry supports legislation to facilitate business operations. Commission Commission welcomes agreement by Member States on Pharmaceuticals Reform welcomes agreement by Member States on Pharmaceuticals 09 Pharmacovigilance ｨC Industry strongly supports the strengthening of the EU market surveillance and pharmacovigilance system. 09 Added Therapeutic Value ｨC Industry believes that introduction of the concept of "added therapeutic value" as a criterion for product registration would have a negative impact on public health. 09 Information to Patients - EFPIA welcomes steps that allow patients and consumers better access to medicines information. "If these points are not addressed, Europe will take a serious step backwards. We support the Commission ｯs initial proposal on regulatory data protection (10+1 years), a strong and effective EMEA, and improvements in the Centralised Procedure to allow business flexibility", declared Sir Tom McKillop, EFPIA President and CEO of AstraZeneca. "We call on EU Member States to encourage pharmaceutical innovation. In the light of current and future disease threats (e.g. SARS), it is clear that patients and Europe in general can only benefit from industry ｯs capacity to innovate to defeat disease. In any event, the future of Europe will not be secured by its ability to copy". Brussels, 2 June 2003: Today, the EU Health Ministers reached an agreement with qualified majority on the proposals by the European Commission to modernise the current pharmaceutical legislation in Europe. These proposals consist of a package of proposals for three legislative acts: a Regulation on the European Medicines Evaluation Agency and its marketing authorization procedure and two Directives on human medicines and on veterinary medicines respectively. Erkki Liikanen, European Commissioner for Enterprise said: "with today's agreement, we have taken an important step towards ensuring that Europe gets a more robust, modern, effective and competitive regulatory framework for pharmaceuticals. Despite the fact that Reform For any further information, please visit the EFPIA website www.efpia.org 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 39

13EFPIA ANNUAL MEETINGS ATHENS 2003 the Member States on some issues did not follow our proposal, this is a well balanced compromise. We are now looking forward to discussing these issues with the European Parliament with a view to hopefully formally adopt this regulatory package by the end of the year." At today's meeting of the Health Council, the Member States focused their discussions on two points of particular importance, namely the scope of the mandatory centralised marketing authorization procedure and the so-called data protection scheme. These two issues have been, from the very beginning of the Council discussions, the more sensitive ones. Regarding the scope of the mandatory centralised marketing authorisation scheme, the Member States agreed that this should cover medicines for the treatment of cancer, aids, neuro-degenerative diseases and diabetes. In addition, the Member States agreed that the industry would have the choice between the centralised procedure and a de-centralised marketing authorisation procedure (at Member State level coupled with a scheme of mutual recognition) for medicines for other types of diseases. The Commission had initially proposed that all medicines containing new substances would be covered by the centralised procedure. Erkki Liikanen said: "the reinforcement of the centralised procedure will help speed up the marketing authorisations in Europe. This will mean faster access to market for the pharmaceutical industry and quicker access to newer and better medicines for patients for these types of illnesses. This is a genuine win-win situation." Regarding the period of data protection for medicines, authorisied under the mandatory centralised procedure, the Member States agreed that this should be ten years with the possibility to extend this by one year if the producer can demonstrate that the medicine in question can be used for a new treatment. For medicines authorised under the de-centralised procedure or under the optional centralised procedure, the period would also be ten years with the possibility of generic medicines to launch their application for marketing authorisation two years before the expiry of this ten years period. Erkki Liikanen said: "this agreement represents a good balance between keeping the necessary incentives for innovation in Europe whilst ensuring a better access for Europe's patients to generic medicines". EU Council Gives Mixed Signal on Innovation and Research in Political Agreement on EU Pharmaceutical Legislation Brussels, 3 June - The Employment, Social Policy, Health and Consumer Affairs EU Council yesterday reached a 'political agreement' on proposals designed by the Commission to improve the regulatory framework for human medicines in Europe1. 09 While EFPIA welcomes some aspects of these wide-ranging proposals, it regrets that the Council has missed an important opportunity by not fully supporting the Commission's proposal to provide 10 years of regulatory data protection for all new products, across the board. Agreement on full 10 years data protection in mandatory Centralised Procedure is positive for innovation. However, the agreement to provide a weaker level of protection for all products registered through the Decentralised Procedure2, and optional Centralised, misses the opportunity to boost For any further information, please visit the EFPIA website www.efpia.org 40 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13the competitiveness and innovative capacity of the European pharmaceutical industry, and the research that patients need and expect. 09 The agreement on one additional year of data protection for significant new indications for mandatory products in the Centralised Procedure is welcomed. However, the Council's decision not to provide similar data protection for significant new indications in other disease areas is illogical, provides no support for research and innovation, and is ultimately detrimental to the interests of patients with these diseases. 09 EFPIA welcomes the agreement to build the EMEA 3/Centralised Procedure into a truly world class regulatory system for the registration of all new pharmaceutical products in Europe. 09 Finally, in view of the lack of agreement on the draft Veterinary Directive (also part of the legislative package), EFPIA remains concerned over the extremely tight timetable for completion of this crucial legislation prior to Enlargement in 2004. Unless a 'Common Position' is reached in Council on the whole package by October 2003, the Commission's legislative objectives - to guarantee a high level of health protection for EU citizens, to boost the competitiveness of the EU pharmaceutical industry and to simplify/rationalise the European regulatory system in order to prepare for enlargement - may not be achieved. 1. Amended Proposal for a Directive of the European Parliament and of the EU Council amending Directive 2001/83/EC on the Community Code relating to medicinal products for human use 2. For certain products (biotech products and medicines to treat AIDS, cancer, neurodegenerative diseases and diabetes) authorisation would be mandatory through the Centralised Procedure 3. European Agency for the Evaluation of Medicinal Products THE ROLE OF 6ﾒ2HE ROLE OF REGULATORY DATA PROTECTION FOR PATIENTS AND INNOVATION REGULATORY DATA PROTECTION FOR PATIENTS AND INNOVATION 09 Regulatory data protection encourages the development of new medicines for patients. Regulatory Data Protection plays a vital role when patent protection is weak or does not exist. This is the case for about 5 to 10% of medicinal products. The role of Data Protection is crucial in these cases as it gives the necessary incentive to develop important and life-saving treatments for patients. 09 Regulatory data protection refers to the protection of the clinical and pre-clinical data aimed at proving that a new compound is safe and effective and which pharmaceutical companies submit to regulatory authorities when they seek marketing authorisation for a new medicine. This is a massive undertaking involving patients, doctors and scientists in collecting and analysing huge amounts of information. These tests generally take between 10-12 years to conduct and represent a considerable investment (up to 500 million euros) for innovative pharmaceutical companies that complete them. 09 The purpose of data protection is to protect this investment against unfair commercial use. During the data protection period, a generic manufacturer cannot refer to the data collected by a research-based company to register and launch a generic version of the same product. For any further information, please visit the EFPIA website www.efpia.org 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 41

13EFPIA ANNUAL MEETINGS ATHENS 2003 EFPIA COMMEMORATES 25 YEARS OF MEDICINE RESEARCH "WE CAN ｯT STOP NOW", DECLARES PROF. TREVOR JONES Athens (Greece), 26 May 2003 ｨC To mark its 25th anniversary (1978-2003), the European Federation of Pharmaceutical Industries and Associations (EFPIA) today inaugurated a special exhibition that will travel around Europe to illustrate the benefits and prospects of pharmaceutical innovation for patients. "Medicines for Mankind" celebrates the key contribution of pharmaceutical research to medical progress by presenting a snapshot overview of what research is happening in some 25 therapeutic areas ｨC It looks back on achievements and forward to opportunities for future medicines that are expected to further improve human health and well-being. The supporting booklet and accompanying documentation complement the exhibit by providing factual information accessible to anyone with an interest in a particular disease area. The aim is to provide a source of general information which is by no means comprehensive, but which should help European publics better understand a range of conditions, the nature of treatments available, as well as current and future research prospects. Prof. Trevor Jones, Director General of the Association of the British Pharmaceutical Industry (ABPI) and Chairman of EFPIA ｯs Group of Research Directors, declared: "Medical care has undergone a total transformation over the past decades. Indeed, 25 years ago, our understanding of the cause of illness was very limited. Through our intensive, lengthy, highly complex and dedicated research effort, new generations of therapies have been introduced that have revolutionised medicine, making once life-threatening diseases uncommon, and allowing millions of people to be treated and lead better or more normal lives. Major achievements have been made in the treatment of infectious diseases (like diphtheria, tuberculosis) and childhood illnesses, some forms of cancer, nervous disorders, stomach ulcers, asthma, hypertension and diabetes, to name but a few. Today, over 90,000 pharmaceutical industry scientists in Europe are researching new cures and innovative therapies for cancer, heart disease, HIV/AIDS, Alzheimer ｯs, Parkinson ｯs, arthritis, osteoporosis, cystic fibrosis and many other diseases. Researching the medicines of the future holds an alluring promise of answers to many of the universal problems of disease and old age. There may not be miracle cures yet, but ｮMedicines for Mankind ｯ points the way towards a brighter future for patients in Europe and all over the world. We cannot stop now!" 42 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13EFPIA CALLS FOR EU ACTION TO ENCOURAGE THE DEVELOPMENT OF BETTER MEDICINES FOR CHILDREN Athens (Greece), 26 May 2003 ｨC In the context of its Annual Meetings, the European Federation of Pharmaceutical Industries and Associations (EFPIA) today organised a workshop on "Medicines for Children in the European Union" with the aim to assess and discuss the current and future scientific, regulatory, and legal frameworks, to respond to the needs for optimal medications for children. Keynote speakers included representatives from public authorities, regulators, paediatricians, patients organisations, and executives of the pharmaceutical industry: Mrs Frｨｦdｨｦrique Ries, Member of European Parliament, Dr Philippe Brunet, European Commission, Enterprise Directorate-General (Pharmaceuticals Unit: Legislative Framework and Market Authorisations), Dr Daniel Brasseur, Committee for Proprietary Medicinal Products (CPMP) and Paediatrics Expert Group at EMEA, Mr Ijsbrand Poortman, European Alliance of Neuromuscular Disease Associations and European Platform for Patients' Organisations, Science and Industry (EPPOSI), Dr Josｨｦ Ramet, Confederation of European Specialists in Paediatrics, and Dr Roger Bickerstaffe, European Forum for Good Clinical Practice. On behalf of the research-based pharmaceutical industry, Dr Daniel Vasmant, Chairman of EFPIA ｯs specialised working group on paediatrics, underlined the urgent need for Community measures to: 09 Encourage paediatric research and the development of specific medicines to treat diseases in children 09 Ensure a substantial and increased European contribution to the worldwide process of providing better medicines for children. Dr Vasmant called on all interested parties to make this their priority goal, and to foster open dialogue and exchanges in its achievement. In this line of thought, EFPIA released a new position paper, which provides detailed considerations in support of an effective proposal for medicinal products for paediatric use. MEDICINES FOR CHILDREN FOR CHILDREN The issue: Meeting the specific health needs of a fifth of the EU population In the European Union, 75 million individuals are younger than 16 years of age, a number that will reach almost 100 million in a Community enlarged to 25 Member States. The research-based pharmaceutical industry is actively contributing to improving their health and welfare. Thanks to new medicines and treatments, medical progress has been achieved in numerous paediatric therapeutic fields, including haematology, oncology, cardiac or renal transplantation, vaccination. Major improvements are also reported in the treatment of asthma, infectious diseases, neonatal respiratory distress, HIV, diabetes, neuropsychological dysfunctions, cystic fibrosis, or in the relief from pain. However, there is a lot to be done still to ensure that European children benefit from adapted medicines. As children are not "small adults", specific studies must be conducted to ensure that medicines prescribed in paediatric populations are suitable to their characteristics and needs. For example, a medicinal product intended for children requires appropriate dosage and presentation to ensure that it can be administered safely and easily. However, such pharmaceutical research involve specific considerations among which, timing of paediatric development, identification of appropriate paediatric formulations, difficulty in conducting pharmacokinetic studies, For any further information, please visit the EFPIA website www.efpia.org 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 43

13EFPIA ANNUAL MEETINGS ATHENS 2003 conduct of tailored efficacy studies, and need to minimise risk and distress for children. This is made more complex by the specificity of various paediatric age groups (ranging from neonates to adolescents), as well as stringent ethical requirements surrounding clinical studies. The development of medicines in paediatric populations involves greater risk-taking by the originator. These R&D activities are nevertheless paramount as there is concern over the use of medicines in children outside the conditions under which the products have been approved (or "off-label use"). Government officials, the scientific community, health professionals, patients and their parents, and the research-based pharmaceutical sector are all in agreement that measures are urgently needed to ensure optimal treatments for children. Crucial need: Support and stimulus for the development of medicines for children ｯs use The need to encourage paediatric research was already highlighted in December 2000 in a Resolution of the European Health Council. It was reiterated in May 2002 in the framework of the G-10 High Level Group on Innovation and Provision of Medicines, which highlighted the need for Commission and Member States to "put in place an effective policy in terms of incentives to research and support the development and marketing of orphan and paediatric medicines". The announcement of a European Commission ｯs initiative in February 2002, with the release of a consultation paper outlining some suggested approaches, raised hopes among relevant interested parties. However, the research-based pharmaceutical industry in Europe is still expecting specific, concrete measures to provide the necessary support and stimulus to R&D activities for paediatrics in the Community. It is time to ensure a substantial and increased European contribution to the worldwide process of providing better medicines for children. 44 6ｾ4f6ﾑ86ﾑ8 02006ｦ004080ｹ0 47

13INNOVATIVE MEDICINES CAN SIGNIFICANT INNOVATIVE MEDICINES CAN SIGNIFICANTLY IMPROVE PUBLIC HEALTH IN ACCESSION COUNTRIES, STRESSES EFPIA IMPROVE PUBLIC HEALTH IN ACCESSION COUNTRIES, STRESSES EFP Health and Enlargement Role of the pharmaceutical industry Athens (Greece), 28 May 2003 ｨC On the occasion of its Annual Meetings, the European Federation of Pharmaceutical Industries and Associations (EFPIA) organised a workshop on EU enlargement entitled "European Healthcare in 2010", bringing together over 180 EU and accession countries ｯ policy-makers as well as senior pharmaceutical industry delegates. Although EU Enlargement is just around the corner ｨC with ten countries set to join the EU on 1 May 2004 ｨC EFPIA Director-General Brian Ager pointed out that accession countries still face enormous public health and health care challenges and that the standard of healthcare provision in accession countries have actually not been part of the accession negotiations, which concentrated on candidate countries capability to implement the acquis communautaire. The Workshop had instead focused on the issues that would matter most for the citizens of the new members ｨC the evolution of healthcare needs, the reform of healthcare systems, the empowerment of patients and the role of the EU. Recent Commission analysis had suggested that it might take the new members 40 years to "catch up" with the existing members, both in GDP and in healthcare investment. Mr Ager questioned whether more could be done to bridge the "health gap". Referring to a recently observed trend of some accession countries to respond to external financial disciplines by reducing the share of their budget dedicated to healthcare, Friedrich Breitenstein, chair of EFPIA ｯs Enlargement Action Team, challenged the assumption that this was cost-free, arguing that increased investment in healthcare is absolutely critical to the longer-term success of enlargement. It must be clear that innovative medicines can play a significant role in improving the quality and efficiency of healthcare delivery as well as improving overall socio-economic welfare. "Our priority therefore is to ensure that our research-based industry is rightly seen and valued in the Enlarged Europe as an important and positive contributor to public health", said Mr Breitenstein. "The success of the EU enlargement project in the pharmaceutical area will depend on guaranteeing the flow and availability of innovative medicines in newly acceding EU states, without jeopardising the foundations and legitimate interests of European research-based companies", stated Mr Breitenstein. 02006ｦ004080ｹ0 47 6ｾ4f6ﾑ86ﾑ8 45

132003 To 04.6ｾ4. 02o0ｸ7 0903fi00 03o0ｹ0: A070206apple03fi00 03o06:. 6ｾ40ｸ70206 070702090ｹ0 (Menarini) 6ｾ4apple. 08 03030703090ｹ0 (Novartis Hellas), 03. 09 07 04040702090ｹ0 (GlaxoSmithKline), ﾒ. 09apple 0702ｨB6ｧ80ｹ0 (UCB Pharma), 02. 6ｾ4 02000303 036ｧ9 090ｹ0 (Janssen-Cilag Pharmaceutical), 6ｾ402. 6ｾ4020008 076ｧ9 090ｹ0 (Boehringer Ingelheim), 04. 020603060602090ｹ0 (02 0300 0400036 5 6ｧ903030ｸ7).. 縺03 0000 02 陦 0ｹ0: T. K0ｸ70306 02o6ｦ0 (Organon Hellas) T 006ｧ9 0ｹ0: B. N000607 0ｹ0 (Cana) M 閨0309: 09. ﾞappleo0402o036ｧ9 090ｹ0 (Abbott Laboratories), ﾞ0702. 08o0906 02ｨB6ｧ80ｹ0 (Sanofi Synthelabo), 09. 縺0003o030ｸ7000702o0ｹ0 (09. 03. 縺0003o030ｸ7000702o0ｹ0), ﾒ. 6ﾑ80ｸ70306apple6ｧ9 090ｹ0 (Genesis Pharma), 09. ﾒ0702040602 0ｹ0 (Faran), 09. 09appleo0402fiappleo0ｸ703o0ｹ0 (Pfizer Hellas). 6ﾑ802 06036ｧ9000ｹ0-09 閨0309 02080ｸ7 Member Companies 1. ABBOTT LABORATORIES E A6ｾ4 ABEE 2. ADELCO A.E. 3. ALCON LABORATORIES E A6ｾ4 A.E. 4. ALLEN 02 0300 02000ｸ70206026ｧ8 A. E. 5. ALVIA A.E. 6. AMERSHAM Health A.E. 7. ASTRAZENECA A.E. 8. AVENTIS Pharma AEBE 9. BAXTER HELLAS E09E 10. BAYER E A6ｾ4 ABEE 11. VIAN A.E. 12. VIANEX A.E. 13. VIOSER A.E. 14. BOEHRINGER INGELHEIM E A6ｾ4 A.E. 15. BRISTOL MYERS SQUIBB A.E.B.E. 16. CANA A.E. 17. CHIESI HELLAS AEBE 18. P.N. GEROLYMATOS A.E.B.E. 19. GALDERMA 6ﾑ8 ﾞ6ｾ4 ﾞ.6ﾑ8. 20. ELPEN A. E. 21. GALENICA A.E. 22. GENESIS Pharma A. E. 23 GEROMEDICA A.E. 24. GLAXOSMITHKLINE AEBE 25. HELP A.B.E.E. 26. I.T.F. Hellas A.E. 27. JANSSEN - CILAG PHARMACEUTICAL AEBE 28. KOPER A.E. 29. LAVIPHARM A.E. 30. LAPAPHARM A.E. 31. LEO HELLAS 02 0300 02000ｸ702060207 0903o0ｸ8fi0702 E.09.E. 32. LUNDBECK HELLAS A.E. 33. MEAD JOHNSON AEBE 34. MEDEXIS AEBE 35. MENARINI E A6ｾ4 A.E. 36. MINERVA A.E. 37. NEO02APAN 38. B. NEIADAS & SONS A.E. 39. NOVEXAL HELLAS E09E 40. NOVARTIS HELLAS A.E. 41. NOVO NORDISK E A6ｾ4 E09E 42. NYCOMED HELLAS A.E. 43. ORGANON HELLAS A.E.E. 44. OCTAPHARMA HELLAS ﾞ.6ﾑ8. 45. PHARMA FABRE A.E. 46. PHARMACIA HELLAS A.E. 47. PIERRE FABRE 02070300 02 A. E. 48. PFIZER HELLAS A.E. 49. REMEK 02 0300 02000ｸ702060207 A.E. 50. ROCHE HELLAS A.E. 51. SANOFI SYNTHELABO A.E. 52. SANTA ABEE 53. SERONO Hellas A.E. 54. SERVIER HELLAS E09E 55. SCHEPA O.E. 56. SCHERING PLOUGH A02BEE 57. SOLVAY PHARMA M.E09E 58. FAMAR A.E. 59. FARAN ABEE 60. FARMANEL A.E. 61. FARMASERV LILLY A.E.B.E. 62. FARMEX AE. 63. FRESENIUS KABI Hellas A.E. 64. FOURNIER Hellas A.E. 65. UCB PHARMA A.E. 66. WYETH HELLAS A.E.B.E.

13Eapple060203oapple 閨0ｹ0 04.6ｾ4. 6ﾑ8apple060203oapple6ｧ8 05000007020ｷ307 08appleo0ｸ70309006ｧ9o0ｸ7 0809006ｧ9 0ｹ0 0903fi00 03o0ｹ0 : 04. 020603060602090ｹ0 (FARMASERV-LILLY ﾞ.6ﾑ8.) 09. ﾞappleo0402o036ｧ9 090ｹ0 ( ﾞ0808O6ﾒ26ﾒ2 Labor. A.E.) 0103. 08 07 0603o0ｸ7 (JANSSEN CILAG A.E.) ﾞ0702. 08o0906 02ｨB6ｧ80ｹ0 (SANOFI SYNTHELABO A.E.). 08o0906 02ｨB6ｧ80ｹ0 (GLAXOSMITHKLINE A.E.) ﾆ. 08o04020602040707o0ｸ7 (GENESIS Pharma A.E.) 6ﾑ8. 罍 0300 070209 (SERVIER Hellas) 09. 縺0003 04fiappleo0ｸ703o0ｹ0 (AVENTIS Pharma) E. Z6ｧ803090ｹ0 (BOEHRINGER ING.) 09. ﾒ0702040602 0ｹ0 (FARAN A.E.) 09. ﾒo04006ｧ9 090ｹ0 (BAYER HELLAS A.E.) 6ﾒ2. ﾒ0ｸ70306 02o6ｦ0 (ORGANON A.E.) 09. 09 0302oappleo6ｦ003o0ｸ7 ( ﾞ0808O6ﾒ26ﾒ2 Labor. A.E.) 09. 09 0402o03070209 (PFIZER A.E.) 04. 09 0ｸ703o00000702090ｹ0 (F ﾞR09 ﾞ036ﾑ8L ﾞ.6ﾑ8.) A0602. 09090306060709 (PHARMACIA Hellas) 03. 09o0ｸ702ｨBo6ｦ003090ｹ0 (WYETH Hellas) 09. 09applefi0402o6 506020ｹ0 (09ｦﾐ036ﾑ80608 ﾞ ﾞ.6ﾑ8.) 09. 09appleo0402fiappleo0ｸ703o0ｹ0 (PFIZER A.E.) A. 090ｷ300046ｧ9 o0ｸ7 ( ﾞSTRA ZENECA) ﾒ. 0302fi0302 0ｹ0 (ROCHE Pharmaceuticals) 03. 6ｦ10007o o046ｧ9 o0ｸ7 (GENESIS Pharma) ﾒ. 09 apple 030ｷ30007 (JANSSEN CILAG A.E.). 0903o 03fi00o0ｸ7 ( ﾞ0808O6ﾒ26ﾒ2 Labor. A.E.) 6ｾ4. 6ｾ402 040607fi0ｹ0 (BRISTOL-MYERS SQUIBB) 05. 6ﾒ2 0402 02ｨB6ｧ80ｹ0 (SERONO Hellas) M. 6ﾒ2ｨB 閨07 (09ｦﾐ036ﾑ8RV ﾞ ﾞ.6ﾑ8.) 05. 6ﾒ2036ｦ0080ｷ307 (6ﾑ8LP6ﾑ803 ﾞ.6ﾑ8.) 08. 09000702 0803070902 0ｹ0 (6ﾑ8LP6ﾑ803 ﾞ.6ﾑ8.) 07 apple030903. 00 閨03o0ｹ0 B. T040002o6ｦ003 0ｹ0 (UCB Hellas) M. 0303o03o0907 (09ｦﾐ036ﾑ8RV ﾞ ﾞ.6ﾑ8.) 6ｾ4. 09000307 6ﾑ8apple060203oapple6ｧ8 05000007020ｷ307 08appleo0ｸ70309006ｧ9o0ｸ7 6ﾑ8030706026ｧ80ｹ0 O0602o07o006ｧ9 0ｹ0 02 06 O0602o07o0006020607 ｨC 6ﾑ80309 0406 0207 05 閨00 02 0903fi00 03o0ｹ0 : 02. 6ｾ4 02000303 036ｧ9 090ｹ0 (JANSSEN CILAG A.E.) 6ｾ4apple. 08 03030703090ｹ0 (NOVARTIS Hellas A.E.) N. B6ｧ9 03 0ｹ0 (FAMAR). 0803fi0702ｨBo0ｹ0 (SERONO Hellas) ﾞ0702. 08o0906 02ｨB6ｧ80ｹ0 (SANOFI SYNTHELABO A.E.) M. Bo030007 09 (PHARMACIA Hellas) 09. 縺0003o030ｸ7000702o0ｹ0 (09.03. 縺6ﾑ806O 0809 ﾞ6ﾒ2O6ｾ4 ﾞ.6ﾑ8.) H. 縺000ｷ30309 0702ｨB070ｹ0 (BRISTOL-MYERS SQUIBB) ﾒ. 04 6ｧ902o0ｹ0 (GALDERMA 6ﾑ80303070ｹ0) T. ﾆ00036 5 020702090ｹ0 (WYETH Hellas) 03. 09 07 04040702090ｹ0 (GLAXOSMITHKLINE A.E.). 09apple6ｧ903 0ｹ0 ( ﾞ0808O6ﾒ26ﾒ2 Laboratories) 04. 09 030702 0ｹ0 (ROCHE Pharmaceuticals) E. 09 apple fi0906 0707090ｹ0 (FOURNIER Hellas) ﾆ. 09 apple 0ｸ80ｷ3070707o0ｸ7 (FRESENIUS KABI) 09. 06 000702090ｹ0 (GENESIS Pharma). 01030ｸ704o04apple0703090ｹ0 6ﾑ8apple060203oapple6ｧ8 040900o046ｧ90ｷ307 08appleo03 閨04000ｷ307 0903fi00 03o0ｹ0 : 6ｾ4apple. 08 03030703090ｹ0 (NOVARTIS A.E.). ﾞ03006 506ｨBfiappleo0ｸ703o0ｹ0 (NYCOMED A.E.) 09. 縺06 04076ｧ8 (WYETH Hellas). ﾒ 03 0702ｨB0702090ｹ0 (FRESENIUS KABI) 09. ﾒ 04 0302ｨB060707 (LAVIPHARM A.E.) 6ｾ4. ﾒfi030306 0ｹ0 (ASTRAZENECA) 09. 09 03020002070209 (ROCHE Pharmaceuticals) 01. 09apple 030707o0ｹ0 (GEROMEDICA A.E.) ﾒ. 09apple 0702ｨB6ｧ80ｹ0 (UCB Pharma A.E.) 09. 09appleo0402fiappleo0ｸ703o0ｹ0 (PFIZER A.E.) 6ｾ4. 6ｾ402 040607fi0ｹ0 (BRISTOL-MYERS SQUIBB) ﾒ. 01 02ｨB090906 07070702o0ｹ0 (JANSSEN CILAG A.E.) 6ｾ4. 09000307 ﾆ. 09 0902030703 6ﾑ8apple060203oapple6ｧ8 6ﾑ80ｸ7030ｷ3apple 0ｸ8020607 08appleo03 閨04000ｷ307 0903fi00 03o0ｹ0 : 6ｾ402. 6ｾ4020008 076ｧ9 090ｹ0 (BOEHRINGER ING.) 09. 縺06 04076ｧ8 (WYETH Hellas). 040003000002ｨBfi0903o0ｸ7 (6ﾑ8LP6ﾑ803 ﾞ.6ﾑ8.) ﾒ. 6ﾑ80ｸ70306apple6ｧ9 090ｹ0 (GENESIS Pharma A.E.) 09. 09appleo0402fiappleo0ｸ703o0ｹ0 (PFIZER A.E.) B. 090ｷ300046ｧ9 o0ｸ7 ( ﾞSTRA ZENECA) 08. 03000607 0ｹ0 (CANA A.E.) 08. O0602o07fi00o0ｸ7 (JANSSEN CILAG A.E.). 09o 0900 02070ｹ0 (FOURNIER Hellas) 6ｾ4. 6ｾ402 040607fi0ｹ0 (BRISTOL-MYERS SQUIBB) 6ｾ4. 09000307. 01030ｸ704o04apple0703090ｹ0 6ﾑ8apple060203oapple6ｧ8 05000007020ｷ307 08appleo0ｸ70309006ｧ9o0ｸ7 ﾞ0707apple020ｸ701090ｹ0 0903fi00 03o0ｹ0 : 03. 09 07 04040702090ｹ0 (GSK A.E.). 縺02o0ｸ7ｨBo6ｦ003090ｹ0 (NYCOMED A.E.) 09. 04 0402 03oappleo6ｦ003o0ｸ7 (ROCHE Pharmaceuticals) 09. ﾒ0702040602 0ｹ0 (FARAN A.E.) 09. ﾒo04006ｧ9 090ｹ0 (BAYER HELLAS A.E.). ﾒ03 04oappleo0ｸ7030702o0ｹ0 (FRESENIUS KABI) A. 000202fi0ｹ0 (SERVIER Hellas) 03. 09o0ｸ702ｨBo6ｦ003090ｹ0 (WYETH Hellas) ﾒ. 09apple000300apple0003060707 (GENESIS Pharma) 08. 09 07fiappleo0ｸ703o0ｹ0 ( ﾞ0808O6ﾒ26ﾒ2 Laboratories) B. 09000702 0803070902 0ｹ0 (6ﾑ8 096ﾑ803 ﾞ.6ﾑ8.) 02. 6ｾ4 02000303 036ｧ9 090ｹ0 (JANSSEN CILAG A.E.) 6ｾ4. 6ｾ402 040607fi0ｹ0 (BRISTOL-MYERS SQUIBB) 6ｾ402. 6ｾ4020008 076ｧ9 090ｹ0 (BOEHRINGER ING. A.E.) 05. 6ﾒ2 0402 02ｨB6ｧ80ｹ0 (SERONO Hellas) 04. 020603060602090ｹ0 (F ﾞR09 ﾞS6ﾑ8RV LｦﾐLL08 ﾞ.6ﾑ8.) ﾒ. 0103o07fiappleo0ｸ703o0ｹ0 (FOURNIER Hellas) M. 0303o03o0907 (09ｦﾐ036ﾑ8RV ﾞ ﾞ.6ﾑ8.). 01030ｸ704o04apple0703090ｹ0 6ﾑ8apple060203oapple6ｧ8 6ﾒ200020009036ｧ90ｷ304090ｹ0 0903fi00 03o0ｹ0 : ﾒ. 09apple 02ｨB6ｧ80ｹ0 (UCB Pharma A.E.). 040003000002ｨBfi0903o0ｸ7 (6ﾑ8 096ﾑ803 ﾞ.6ﾑ8.) ﾒ. 6ﾑ80ｸ70306apple6ｧ9 090ｹ0 (GENESIS Pharma A.E.) A. ﾒ 03fi02090ｹ0 ( ﾞSTRA ZENECA) 6ﾒ2. ﾒ0ｸ70306 02o6ｦ0 (ORGANON A.E.) B. 03000607 0ｹ0 (CANA A.E.) 02. 09000203070209 (PFIZER A.E.) 03. 6ｾ4 03 0702fiappleo0ｸ703o0ｹ0 (JANSSEN CILAG A.E.) 6ｾ400 fi03000ｹ0 02060ｹ0 Eapple060203oapple 閨0ｹ0 000002 閨04o0ｸ707 ex officio o 0903fi00 03o0ｹ0 02.. K03 040703090ｹ0 02 06 o 縺00070602fi0ｹ0 0406000ｸ7030ｸ707026ｧ80ｹ0 02. 02. M 0909 03o6ｦ004090ｹ0.

136ﾑ8 ﾒ04 ﾌ6ｾ46ﾑ8ｦﾐ6ｾ4 6ｾ4.02.6ﾑ8.6ﾑ8. 6ｾ46ｦ007 000400o0ｹ0 02 0300 02000ｸ70206020607 6ﾑ8apple06040006036ｧ804000ｷ307 6ﾑ8030307 o0ｹ0 000ｷ308. 08 040603 閨0ｷ30ｹ0 縺000ｷ303096ｧ9o0ｸ7 30 & 09060203070ｹ0 ﾞ046ｧ9 0ｹ0, 15233 01 030707 0306 6ﾒ20903.: 68 91 101 Fax: 68 91 060, 68 21 040 ｦﾐnternet: www.sfee.gr- e- mail: sfee@otenet.gr 00 閨03080ｹ0 08006ｧ903080ｸ7