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1 Teru Ogura, Tomoko Yamada-Inagawa, [email protected] AAA family ATPases : ring-shaped chaperones which catalyze energy-dependent conformational changes of proteins

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7 29) Braun, S., Matuschewski, K., Rape, M., Thorns, S., Jentsch, 2) Patel, S., Latterich, M. : Trends Cell Biol., 8, 65-71(1998) S. : EMBO J., 21, (2002) 30) Singleton, M. R., Sawaya, M. R., Ellenberger, T., Wigley, D. 4) Ogura, T., Wilkinson, A. J.: Genes Cells, 6, (2001) 5) Neuwald. A. F., Aravind, L., Spouge, J. L., Koonin, E. V. : Genome Res., 9, (1999) 6) Keiler, K. C., Waller, P. R., Sauer, R. T. : Science, 271, (1996) 8) Reid, B. G., Fenton, W. A., Horwich, A. L., Weber-Ban, E. U.: Proc. Natl. Acad. Sci. USA, 98, (2001) 9) Lee, C., Schwartz, M. P., Prakash, S., Iwakura, M., Matouschek, A.: Mol. Cell, 7, (2001) 10) Kihara, A., Akiyama, Y., Ito, K. : EMBO J., 18, (1999) 11) Weber-Ban, E. U., Reid, B. G., Miranker, A. D., Horwich, A. L.: Nature,401,90-93(1999) 12) Kim, Y.-I., Burton, R. E., Burton, B. M., Sauer, R. T., Baker, T. A. : Mol. Cell, 5, (2000) 13) Ortega, J., Singh, S. K., Ishikawa, T., Maurizi, M. R., Steven, A. C. : Mol. Cell, 6, (2000) 14) Karata, K., Verma, C., Wilkinson, A. J., Ogura, T. : Mol. Microbiol., 39, (200 1) 15) Seong, I. S., Oh, J. Y., Yoo, S. J., Seol, J. H., Chung, C. H. FEBS Lett., 456, (1999) 16) Wang, J., Song, J. J., Franklin, M. C., Kamtekar, S., Im, Y. J., Seong, I. S., Lee, C. S., Chung, C. H., Eom, S. H. : Structure, 9, (2001) 17) Song, H. K., Hartmann, C., Ramachandran, R., Bochtler, M., Behrendt, R., Moroder, L., Huber, R. : Proc. Natl. Acad. Sci. USA, 97, (2000) 18) Navon, A., Goldberg, A. L. : Mol. Cell, 8, (2001) 19) Smith, C. K., Baker, T. A., Sauer, R. T.: Proc. Natl. Acad. Sci. USA, 96, (1999) 20) Karata, K., Inagawa, T., Wilkinson, A. J., Tatsuta, T., Ogura, T. : J. Biol. Chem., 274, (1999) 22) Matveeva, E. A., May, A. P., He, P., Whiteheart, S. W. : Biochemistry, 41, (2002) 23) Wang, J., Song, J. J., Seong, I. S., Franklin, M. C., Kamtekar, S., Eom, S. H., Chung, C. H.: Structure, 9, (2001) 24) Meyer, H. H., Shorter, J. G., Seemann, J., Pappin, D., Warren, G.: EMBO J., 15, (2000) 25) Hetzer, M., Meyer, H. H., Walther, T. C., Bilbao-Cortes, D., Warren, G., Mattaj, I. W. : Nature. Cell Biol., 3, (2001) 26) Ye, Y., Meyer, H. H., Rapoport, T. A. : Nature, 414, (2001) 27) Rabinovich, E., Kerem, A., Frohlich, K. U., Diamant, N., Bar- Nun, S. : Mol. Cell. Biol., 22, (2002) 28) Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D. H., Sommer, T. : Nattre. Cell Biol., 4, (2002) B.: Cell, 101, (2000) 31) Vale, R. D. : Trends Cell Biol., 9, M38-M42 (1999) 32) Hirabayashi, M., Inoue, K., Tanaka, K., Nakadate, K., Ohsawa, Y., Kamei, Y., Popiel, A. H., Sinohara, A., Iwamatsu, A., Kimura, Y., Uchiyama, Y., Hori, S., Kakizuka, A.: Cell Death Differ., 8, (2001) 33) Motohashi, K., Watanabe, Y., Yohda, M., Yoshida, M. Proc. Natl. Acad. Sci. USA, 96, (1999) 34) Goloubinoff, P., Mogk, A., Zvi, A. P., Tomoyasu, T., Bukau, B.: Proc. Natl. Acad. Sci. USA, 96, (1999)

Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie

Database Center for Life Science Online Service Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie Matthias P. Mayer*, Toshifumi Tomoyasu* *, Bernd Bukau*, Institut fiir Biochemie and Molekularbiologie Universitat Freiburg Zentrum fur Molekulare Biologie (ZMBH) Universitat Heidelberg E-mail : [email protected]

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